Traits in the Panel: any

An alternative view of the table is available here with all significant tissues.

Trait Name Trait Full Name Panel Author Year Cases* Controls # TAG Sets Top 3 Tissues (GTEx): p (chi2)
G54Diagnoses - main ICD10: G54 Nerve root and plexus disordersUK Biobank (UKBB)Neale Lab20181433610513Esophagus - Mucosa: p = 1.55E-5
Vagina: p = 0.01
Ovary: p = 0.02
C21Diagnoses - main ICD10: C21 Malignant neoplasm of anus and anal canalUK Biobank (UKBB)Neale Lab20181393610554Lung: p = 1.91E-6
Spleen: p = 4.22E-4
Skin - Sun Exposed (Lower leg): p = 0.00868
F45Diagnoses - main ICD10: F45 Somatoform disordersUK Biobank (UKBB)Neale Lab20182413609533Esophagus - Muscularis: p = 0.0081
Adrenal Gland: p = 0.00874
Vagina: p = 0.02
I35Diagnoses - main ICD10: I35 Nonrheumatic aortic valve disordersUK Biobank (UKBB)Neale Lab20189013602933Colon - Sigmoid: p = 0.00262
Esophagus - Gastroesophageal Junction: p = 0.00262
Esophagus - Muscularis: p = 0.00578
D38Diagnoses - main ICD10: D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organsUK Biobank (UKBB)Neale Lab20181073610872Vagina: p = 0.05
Esophagus - Gastroesophageal Junction: p = 0.07
Heart - Left Ventricle: p = 0.07
C49Diagnoses - main ICD10: C49 Malignant neoplasm of other connective and soft tissueUK Biobank (UKBB)Neale Lab20182223609723Brain - Hippocampus: p = 0.00124
Artery - Tibial: p = 0.00269
Brain - Amygdala: p = 0.00308
M05Diagnoses - main ICD10: M05 Seropositive rheumatoid arthritisUK Biobank (UKBB)Neale Lab20182883609065Lung: p = 1.17E-7
Spleen: p = 3.52E-6
Ovary: p = 0.02
N97Diagnoses - main ICD10: N97 Female infertilityUK Biobank (UKBB)Neale Lab20186963604983Brain - Spinal cord (cervical c-1): p = 0.00696
Pancreas: p = 0.02
Spleen: p = 0.03
N64Diagnoses - main ICD10: N64 Other disorders of breastUK Biobank (UKBB)Neale Lab20188443603502Uterus: p = 0.00761
Colon - Transverse: p = 0.02
Breast - Mammary Tissue: p = 0.04
G35Diagnoses - main ICD10: G35 Multiple sclerosisUK Biobank (UKBB)Neale Lab20185663606285Spleen: p = 9.14E-9
Lung: p = 1.11E-6
Whole Blood: p = 4.73E-5
K09Diagnoses - main ICD10: K09 Cysts of oral region, not elsewhere classifiedUK Biobank (UKBB)Neale Lab20182873609073Prostate: p = 0.0018
Breast - Mammary Tissue: p = 0.02
Colon - Transverse: p = 0.02
J84Diagnoses - main ICD10: J84 Other interstitial pulmonary diseasesUK Biobank (UKBB)Neale Lab20183423608523Esophagus - Mucosa: p = 0.02
Liver: p = 0.02
Pancreas: p = 0.03
R49Diagnoses - main ICD10: R49 Voice disturbancesUK Biobank (UKBB)Neale Lab20185653606293Ovary: p = 0.00328
Nerve - Tibial: p = 0.03
Adrenal Gland: p = 0.03
H53Diagnoses - main ICD10: H53 Visual disturbancesUK Biobank (UKBB)Neale Lab20185603606343Lung: p = 0.00415
Small Intestine - Terminal Ileum: p = 0.03
Esophagus - Muscularis: p = 0.05
N47Diagnoses - main ICD10: N47 Redundant prepuce, phimosis and paraphimosisUK Biobank (UKBB)Neale Lab201815433596513Lung: p = 3.31E-5
Pancreas: p = 0.02
Nerve - Tibial: p = 0.03
Z31Diagnoses - main ICD10: Z31 Procreative managementUK Biobank (UKBB)Neale Lab20181873610073Heart - Atrial Appendage: p = 0.02
Thyroid: p = 0.02
Spleen: p = 0.02
N72Diagnoses - main ICD10: N72 Inflammatory disease of cervix uteriUK Biobank (UKBB)Neale Lab20183703608243Lung: p = 0.00153
Brain - Cortex: p = 0.00303
Brain - Frontal Cortex (BA9): p = 0.00495
R56Diagnoses - main ICD10: R56 Convulsions, not elsewhere classifiedUK Biobank (UKBB)Neale Lab201810773601173Vagina: p = 0.01
Brain - Hippocampus: p = 0.01
Muscle - Skeletal: p = 0.02
N63Diagnoses - main ICD10: N63 Unspecified lump in breastUK Biobank (UKBB)Neale Lab201811993599952Small Intestine - Terminal Ileum: p = 9.13E-4
Skin - Not Sun Exposed (Suprapubic): p = 0.00567
Colon - Sigmoid: p = 0.00688
R86Diagnoses - main ICD10: R86 Abnormal findings in specimens from male genital organsUK Biobank (UKBB)Neale Lab20181143610803Spleen: p = 0.0074
Vagina: p = 0.01
Minor Salivary Gland: p = 0.02
T14Diagnoses - main ICD10: T14 Injury of unspecified body regionUK Biobank (UKBB)Neale Lab20181343610603Esophagus - Mucosa: p = 0.01
Small Intestine - Terminal Ileum: p = 0.05
Kidney - Cortex: p = 0.06
Q66Diagnoses - main ICD10: Q66 Congenital deformities of feetUK Biobank (UKBB)Neale Lab20181003610943Small Intestine - Terminal Ileum: p = 0.02
Lung: p = 0.02
Adipose - Visceral (Omentum): p = 0.02
T42Diagnoses - main ICD10: T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugsUK Biobank (UKBB)Neale Lab20185383606563Brain - Hypothalamus: p = 0.0017
Brain - Cerebellar Hemisphere: p = 0.00434
Brain - Anterior cingulate cortex (BA24): p = 0.00674
I95Diagnoses - main ICD10: I95 HypotensionUK Biobank (UKBB)Neale Lab20185663606283Whole Blood: p = 0.00146
Skin - Not Sun Exposed (Suprapubic): p = 0.00385
Skin - Sun Exposed (Lower leg): p = 0.00385
N89Diagnoses - main ICD10: N89 Other noninflammatory disorders of vaginaUK Biobank (UKBB)Neale Lab20187643604302Whole Blood: p = 0.01
Skin - Sun Exposed (Lower leg): p = 0.04
Skin - Not Sun Exposed (Suprapubic): p = 0.06
G81Diagnoses - main ICD10: G81 HemiplegiaUK Biobank (UKBB)Neale Lab20182913609033Brain - Cortex: p = 0.00342
Brain - Hypothalamus: p = 0.00342
Brain - Substantia nigra: p = 0.00823
M65Diagnoses - main ICD10: M65 Synovitis and tenosynovitisUK Biobank (UKBB)Neale Lab201828123583823Artery - Tibial: p = 0.00708
Artery - Aorta: p = 0.02
Artery - Coronary: p = 0.02
L71Diagnoses - main ICD10: L71 RosaceaUK Biobank (UKBB)Neale Lab20181093610853Spleen: p = 0.00352
Nerve - Tibial: p = 0.00696
Artery - Tibial: p = 0.04
Z03Diagnoses - main ICD10: Z03 Medical observation and evaluation for suspected diseases and conditionsUK Biobank (UKBB)Neale Lab201849513562432Skin - Sun Exposed (Lower leg): p = 6.73E-4
Skin - Not Sun Exposed (Suprapubic): p = 0.00189
Spleen: p = 0.0032
N81Diagnoses - main ICD10: N81 Female genital prolapseUK Biobank (UKBB)Neale Lab201875113536834Colon - Sigmoid: p = 0.00137
Artery - Aorta: p = 0.00818
Artery - Tibial: p = 0.00843
D05Diagnoses - main ICD10: D05 Carcinoma in situ of breastUK Biobank (UKBB)Neale Lab201814543597403Breast - Mammary Tissue: p = 9.48E-4
Brain - Cerebellum: p = 0.00259
Minor Salivary Gland: p = 0.00592
N02Diagnoses - main ICD10: N02 Recurrent and persistent haematuriaUK Biobank (UKBB)Neale Lab20184693607253Esophagus - Muscularis: p = 3.74E-4
Colon - Sigmoid: p = 7.8E-4
Esophagus - Gastroesophageal Junction: p = 0.00111
J13Diagnoses - main ICD10: J13 Pneumonia due to Streptococcus pneumoniaeUK Biobank (UKBB)Neale Lab20181693610253Skin - Sun Exposed (Lower leg): p = 2.52E-4
Skin - Not Sun Exposed (Suprapubic): p = 4.48E-4
Prostate: p = 0.03
O46Diagnoses - main ICD10: O46 Antepartum haemorrhage, not elsewhere classifiedUK Biobank (UKBB)Neale Lab20184533607412Minor Salivary Gland: p = 0.00669
Brain - Caudate (basal ganglia): p = 0.03
Ovary: p = 0.03
L28Diagnoses - main ICD10: L28 Lichen simplex chronicus and prurigoUK Biobank (UKBB)Neale Lab20181223610723Artery - Aorta: p = 2.36E-4
Adipose - Subcutaneous: p = 0.00169
Artery - Coronary: p = 0.00396
T17Diagnoses - main ICD10: T17 Foreign body in respiratory tractUK Biobank (UKBB)Neale Lab20182373609573Brain - Spinal cord (cervical c-1): p = 9.97E-4
Brain - Frontal Cortex (BA9): p = 0.0026
Brain - Anterior cingulate cortex (BA24): p = 0.00637
J96Diagnoses - main ICD10: J96 Respiratory failure, not elsewhere classifiedUK Biobank (UKBB)Neale Lab20181943610003Brain - Anterior cingulate cortex (BA24): p = 2.35E-5
Brain - Cortex: p = 4.35E-5
Brain - Amygdala: p = 7.91E-5
Z40Diagnoses - main ICD10: Z40 Prophylactic surgeryUK Biobank (UKBB)Neale Lab20185253606693Muscle - Skeletal: p = 0.00534
Vagina: p = 0.02
Pituitary: p = 0.02
K70Diagnoses - main ICD10: K70 Alcoholic liver diseaseUK Biobank (UKBB)Neale Lab20183443608503Skin - Not Sun Exposed (Suprapubic): p = 0.01
Skin - Sun Exposed (Lower leg): p = 0.02
Artery - Coronary: p = 0.02
I26Diagnoses - main ICD10: I26 Pulmonary embolismUK Biobank (UKBB)Neale Lab201821183590764Liver: p = 1.73E-6
Colon - Transverse: p = 8.95E-4
Stomach: p = 0.0017
A09Diagnoses - main ICD10: A09 Diarrhoea and gastro-enteritis of presumed infectious originUK Biobank (UKBB)Neale Lab201821613590333Breast - Mammary Tissue: p = 0.00443
Esophagus - Muscularis: p = 0.00912
Adipose - Subcutaneous: p = 0.01
J47Diagnoses - main ICD10: J47 BronchiectasisUK Biobank (UKBB)Neale Lab20183933608013Adipose - Subcutaneous: p = 0.00765
Lung: p = 0.02
Brain - Hypothalamus: p = 0.06
B37Diagnoses - main ICD10: B37 CandidiasisUK Biobank (UKBB)Neale Lab20182523609423Ovary: p = 2.14E-4
Vagina: p = 0.00298
Spleen: p = 0.00446
M94Diagnoses - main ICD10: M94 Other disorders of cartilageUK Biobank (UKBB)Neale Lab20183333608613Brain - Hippocampus: p = 3.56E-4
Brain - Hypothalamus: p = 3.56E-4
Brain - Amygdala: p = 6.33E-4
O35Diagnoses - main ICD10: O35 Maternal care for known or suspected foetal abnormality and damageUK Biobank (UKBB)Neale Lab20181063610883Heart - Left Ventricle: p = 0.01
Thyroid: p = 0.01
Kidney - Cortex: p = 0.02
H65Diagnoses - main ICD10: H65 Nonsuppurative otitis mediaUK Biobank (UKBB)Neale Lab20187813604133Heart - Left Ventricle: p = 0.00312
Heart - Atrial Appendage: p = 0.02
Ovary: p = 0.06
Z04Diagnoses - main ICD10: Z04 Examination and observation for other reasonsUK Biobank (UKBB)Neale Lab20184993606953Skin - Not Sun Exposed (Suprapubic): p = 0.02
Skin - Sun Exposed (Lower leg): p = 0.04
Whole Blood: p = 0.07
R11Diagnoses - main ICD10: R11 Nausea and vomitingUK Biobank (UKBB)Neale Lab201822713589233Liver: p = 0.06
Skin - Sun Exposed (Lower leg): p = 0.06
Stomach: p = 0.08
F43Diagnoses - main ICD10: F43 Reaction to severe stress, and adjustment disordersUK Biobank (UKBB)Neale Lab20182273609673Esophagus - Mucosa: p = 0.00864
Skin - Not Sun Exposed (Suprapubic): p = 0.00864
Spleen: p = 0.02
Z53Diagnoses - main ICD10: Z53 Persons encountering health services for specifie procedures, not carried outUK Biobank (UKBB)Neale Lab201817543594403Esophagus - Gastroesophageal Junction: p = 9.92E-4
Heart - Atrial Appendage: p = 0.00396
Esophagus - Muscularis: p = 0.00606
N13Diagnoses - main ICD10: N13 Obstructive and reflux uropathyUK Biobank (UKBB)Neale Lab201813593598353Minor Salivary Gland: p = 0.00287
Whole Blood: p = 0.00562
Muscle - Skeletal: p = 0.02
O36Diagnoses - main ICD10: O36 Maternal care for other known or suspected foetal problemsUK Biobank (UKBB)Neale Lab201811493600453Brain - Cerebellar Hemisphere: p = 0.00671
Brain - Cerebellum: p = 0.01
Colon - Sigmoid: p = 0.01
D24Diagnoses - main ICD10: D24 Benign neoplasm of breastUK Biobank (UKBB)Neale Lab201810893601052Artery - Tibial: p = 0.00211
Colon - Sigmoid: p = 0.02
Prostate: p = 0.02
K57Diagnoses - main ICD10: K57 Diverticular disease of intestineUK Biobank (UKBB)Neale Lab2018126623485325Colon - Sigmoid: p = 8.02E-5
Liver: p = 4.84E-4
Esophagus - Gastroesophageal Junction: p = 5.09E-4
S76Diagnoses - main ICD10: S76 Injury of muscle and tendon at hip and thigh levelUK Biobank (UKBB)Neale Lab20182803609143Brain - Hippocampus: p = 1.42E-4
Brain - Amygdala: p = 4.23E-4
Brain - Substantia nigra: p = 4.23E-4
I46Diagnoses - main ICD10: I46 Cardiac arrestUK Biobank (UKBB)Neale Lab20181673610273Breast - Mammary Tissue: p = 0.00696
Adrenal Gland: p = 0.01
Ovary: p = 0.02
I65Diagnoses - main ICD10: I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarctionUK Biobank (UKBB)Neale Lab20184603607343Whole Blood: p = 0.00887
Spleen: p = 0.01
Lung: p = 0.02
T83Diagnoses - main ICD10: T83 Complications of genito-urinary prosthetic devices, implants and graftsUK Biobank (UKBB)Neale Lab20187263604682Heart - Atrial Appendage: p = 0.03
Kidney - Cortex: p = 0.05
Spleen: p = 0.05
K06Diagnoses - main ICD10: K06 Other disorders of gingiva and edentulous alveolar ridgeUK Biobank (UKBB)Neale Lab20182173609773Kidney - Cortex: p = 3.39E-4
Colon - Transverse: p = 5.83E-4
Prostate: p = 0.00353
H83Diagnoses - main ICD10: H83 Other diseases of inner earUK Biobank (UKBB)Neale Lab20185183606763Esophagus - Gastroesophageal Junction: p = 1.69E-4
Vagina: p = 0.00153
Brain - Amygdala: p = 0.00431
D33Diagnoses - main ICD10: D33 Benign neoplasm of brain and other parts of central nervous systemUK Biobank (UKBB)Neale Lab20182533609413Vagina: p = 0.00224
Brain - Nucleus accumbens (basal ganglia): p = 0.00243
Whole Blood: p = 0.01
N20Diagnoses - main ICD10: N20 Calculus of kidney and ureterUK Biobank (UKBB)Neale Lab201835403576545Whole Blood: p = 0.00647
Kidney - Cortex: p = 0.01
Lung: p = 0.01
J02Diagnoses - main ICD10: J02 Acute pharyngitisUK Biobank (UKBB)Neale Lab20183413608533Muscle - Skeletal: p = 0.002
Artery - Coronary: p = 0.01
Colon - Transverse: p = 0.02
R26Diagnoses - main ICD10: R26 Abnormalities of gait and mobilityUK Biobank (UKBB)Neale Lab20183303608643Minor Salivary Gland: p = 0.03
Adrenal Gland: p = 0.03
Pancreas: p = 0.06
N17Diagnoses - main ICD10: N17 Acute renal failureUK Biobank (UKBB)Neale Lab20187943604003Kidney - Cortex: p = 0.04
Small Intestine - Terminal Ileum: p = 0.05
Brain - Substantia nigra: p = 0.05
S89Diagnoses - main ICD10: S89 Other and unspecified injuries of lower legUK Biobank (UKBB)Neale Lab20181243610702Small Intestine - Terminal Ileum: p = 0.02
Lung: p = 0.02
Pancreas: p = 0.06
F31Diagnoses - main ICD10: F31 Bipolar affective disorderUK Biobank (UKBB)Neale Lab20183713608233Colon - Sigmoid: p = 0.00708
Whole Blood: p = 0.01
Muscle - Skeletal: p = 0.02
K02Diagnoses - main ICD10: K02 Dental cariesUK Biobank (UKBB)Neale Lab201821103590842Muscle - Skeletal: p = 0.04
Brain - Amygdala: p = 0.08
Brain - Anterior cingulate cortex (BA24): p = 0.10
A04Diagnoses - main ICD10: A04 Other bacterial intestinal infectionsUK Biobank (UKBB)Neale Lab20187623604323Heart - Atrial Appendage: p = 0.00559
Muscle - Skeletal: p = 0.00599
Liver: p = 0.00874
I30Diagnoses - main ICD10: I30 Acute pericarditisUK Biobank (UKBB)Neale Lab20181363610583Pituitary: p = 0.00488
Spleen: p = 0.06
Brain - Caudate (basal ganglia): p = 0.10
L50Diagnoses - main ICD10: L50 UrticariaUK Biobank (UKBB)Neale Lab20181433610512Lung: p = 4.79E-4
Adipose - Visceral (Omentum): p = 0.02
Skin - Not Sun Exposed (Suprapubic): p = 0.04
T40Diagnoses - main ICD10: T40 Poisoning by narcotics and psychodysleptics [hallucinogens]UK Biobank (UKBB)Neale Lab20182763609182Prostate: p = 0.00137
Pancreas: p = 0.00387
Adipose - Visceral (Omentum): p = 0.00651
K90Diagnoses - main ICD10: K90 Intestinal malabsorptionUK Biobank (UKBB)Neale Lab20189223602725Spleen: p = 6.24E-9
Lung: p = 2.5E-5
Whole Blood: p = 2.08E-4
C50Diagnoses - main ICD10: C50 Malignant neoplasm of breastUK Biobank (UKBB)Neale Lab201883043528905Breast - Mammary Tissue: p = 4.1E-4
Artery - Tibial: p = 0.00355
Colon - Sigmoid: p = 0.0052
K10Diagnoses - main ICD10: K10 Other diseases of jawsUK Biobank (UKBB)Neale Lab20181883610062Spleen: p = 0.00813
Adipose - Subcutaneous: p = 0.01
Skin - Not Sun Exposed (Suprapubic): p = 0.09
K46Diagnoses - main ICD10: K46 Unspecified abdominal herniaUK Biobank (UKBB)Neale Lab20181063610883Liver: p = 9.93E-4
Artery - Coronary: p = 0.00269
Small Intestine - Terminal Ileum: p = 0.00655
C02Diagnoses - main ICD10: C02 Malignant neoplasm of other and unspecified parts of tongueUK Biobank (UKBB)Neale Lab20181523610423Small Intestine - Terminal Ileum: p = 0.00712
Brain - Cerebellum: p = 0.02
Brain - Cerebellar Hemisphere: p = 0.03
M25Diagnoses - main ICD10: M25 Other joint disorders, not elsewhere classifiedUK Biobank (UKBB)Neale Lab201872183539763Brain - Nucleus accumbens (basal ganglia): p = 0.01
Pituitary: p = 0.01
Skin - Not Sun Exposed (Suprapubic): p = 0.02
S93Diagnoses - main ICD10: S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot levelUK Biobank (UKBB)Neale Lab20181183610763Skin - Sun Exposed (Lower leg): p = 0.00561
Minor Salivary Gland: p = 0.00678
Stomach: p = 0.02
E10Diagnoses - main ICD10: E10 Insulin-dependent diabetes mellitusUK Biobank (UKBB)Neale Lab20184703607245Spleen: p = 1.36E-8
Lung: p = 4.99E-5
Whole Blood: p = 4.41E-4
C22Diagnoses - main ICD10: C22 Malignant neoplasm of liver and intrahepatic bile ductsUK Biobank (UKBB)Neale Lab20181893610053Kidney - Cortex: p = 0.00261
Stomach: p = 0.00761
Thyroid: p = 0.00761
M75Diagnoses - main ICD10: M75 Shoulder lesionsUK Biobank (UKBB)Neale Lab201870403541543Prostate: p = 0.00831
Muscle - Skeletal: p = 0.01
Pituitary: p = 0.02
N23Diagnoses - main ICD10: N23 Unspecified renal colicUK Biobank (UKBB)Neale Lab201814083597863Testis: p = 0.00692
Artery - Tibial: p = 0.00831
Kidney - Cortex: p = 0.01
Z51Diagnoses - main ICD10: Z51 Other medical careUK Biobank (UKBB)Neale Lab20182113609832Thyroid: p = 0.00358
Small Intestine - Terminal Ileum: p = 0.02
Minor Salivary Gland: p = 0.03
R21Diagnoses - main ICD10: R21 Rash and other nonspecific skin eruptionUK Biobank (UKBB)Neale Lab20183783608163Adipose - Visceral (Omentum): p = 0.01
Spleen: p = 0.01
Whole Blood: p = 0.01
K80Diagnoses - main ICD10: K80 CholelithiasisUK Biobank (UKBB)Neale Lab2018105203506745Liver: p = 1.33E-6
Whole Blood: p = 0.00143
Pancreas: p = 0.00215
T81Diagnoses - main ICD10: T81 Complications of procedures, not elsewhere classifiedUK Biobank (UKBB)Neale Lab201855503556443Brain - Anterior cingulate cortex (BA24): p = 0.003
Brain - Frontal Cortex (BA9): p = 0.00471
Brain - Hippocampus: p = 0.00471
E16Diagnoses - main ICD10: E16 Other disorders of pancreatic internal secretionUK Biobank (UKBB)Neale Lab20182953608994Spleen: p = 2.34E-7
Lung: p = 9.36E-6
Pituitary: p = 0.00843
L72Diagnoses - main ICD10: L72 Follicular cysts of skin and subcutaneous tissueUK Biobank (UKBB)Neale Lab201866443545504Nerve - Tibial: p = 6.58E-4
Spleen: p = 9.73E-4
Lung: p = 0.00153
H93Diagnoses - main ICD10: H93 Other disorders of ear, not elsewhere classifiedUK Biobank (UKBB)Neale Lab20181253610693Nerve - Tibial: p = 0.00597
Esophagus - Muscularis: p = 0.02
Brain - Nucleus accumbens (basal ganglia): p = 0.03
M18Diagnoses - main ICD10: M18 Arthrosis of first carpometacarpal jointUK Biobank (UKBB)Neale Lab20188983602963Whole Blood: p = 0.00427
Muscle - Skeletal: p = 0.00655
Adipose - Subcutaneous: p = 0.06
B18Diagnoses - main ICD10: B18 Chronic viral hepatitisUK Biobank (UKBB)Neale Lab20181343610603Brain - Spinal cord (cervical c-1): p = 0.02
Nerve - Tibial: p = 0.02
Testis: p = 0.02
M06Diagnoses - main ICD10: M06 Other rheumatoid arthritisUK Biobank (UKBB)Neale Lab201814013597935Spleen: p = 2.87E-9
Lung: p = 8.01E-7
Small Intestine - Terminal Ileum: p = 4.38E-5
J33Diagnoses - main ICD10: J33 Nasal polypUK Biobank (UKBB)Neale Lab201822073589875Lung: p = 6.41E-8
Whole Blood: p = 4.9E-4
Spleen: p = 0.00108
G95Diagnoses - main ICD10: G95 Other diseases of spinal cordUK Biobank (UKBB)Neale Lab20182223609723Skin - Not Sun Exposed (Suprapubic): p = 0.00158
Skin - Sun Exposed (Lower leg): p = 0.00374
Lung: p = 0.02
R29Diagnoses - main ICD10: R29 Other symptoms and signs involving the nervous and musculoskeletal systemsUK Biobank (UKBB)Neale Lab20188863603083Minor Salivary Gland: p = 6.95E-4
Pituitary: p = 0.00475
Prostate: p = 0.02
K52Diagnoses - main ICD10: K52 Other non-infective gastro-enteritis and colitisUK Biobank (UKBB)Neale Lab201887573524373Uterus: p = 0.01
Brain - Cerebellar Hemisphere: p = 0.04
Brain - Cerebellum: p = 0.07
N87Diagnoses - main ICD10: N87 Dysplasia of cervix uteriUK Biobank (UKBB)Neale Lab201811023600923Whole Blood: p = 0.02
Thyroid: p = 0.04
Brain - Frontal Cortex (BA9): p = 0.07
M35Diagnoses - main ICD10: M35 Other systemic involvement of connective tissueUK Biobank (UKBB)Neale Lab20182113609833Vagina: p = 0.01
Whole Blood: p = 0.01
Liver: p = 0.02
C17Diagnoses - main ICD10: C17 Malignant neoplasm of small intestineUK Biobank (UKBB)Neale Lab20181143610803Brain - Cerebellum: p = 4.76E-4
Brain - Cerebellar Hemisphere: p = 0.0051
Small Intestine - Terminal Ileum: p = 0.00756
I74Diagnoses - main ICD10: I74 Arterial embolism and thrombosisUK Biobank (UKBB)Neale Lab20185103606843Thyroid: p = 5.72E-4
Esophagus - Mucosa: p = 0.00243
Pituitary: p = 0.00243
I27Diagnoses - main ICD10: I27 Other pulmonary heart diseasesUK Biobank (UKBB)Neale Lab20181173610772Artery - Coronary: p = 0.00862
Minor Salivary Gland: p = 0.00862
Muscle - Skeletal: p = 0.00983
R63Diagnoses - main ICD10: R63 Symptoms and signs concerning food and fluid intakeUK Biobank (UKBB)Neale Lab201812793599153Whole Blood: p = 0.0026
Thyroid: p = 0.02
Artery - Tibial: p = 0.03
M72Diagnoses - main ICD10: M72 Fibroblastic disordersUK Biobank (UKBB)Neale Lab201831933580015Colon - Sigmoid: p = 3.44E-4
Esophagus - Muscularis: p = 0.00127
Artery - Tibial: p = 0.00177
M76Diagnoses - main ICD10: M76 Enthesopathies of lower limb, excluding footUK Biobank (UKBB)Neale Lab20182893609053Esophagus - Mucosa: p = 7.34E-6
Vagina: p = 2.28E-5
Brain - Cortex: p = 6.09E-4
O34Diagnoses - main ICD10: O34 Maternal care for known or suspected abnormality of pelvic organsUK Biobank (UKBB)Neale Lab20187913604033Adipose - Visceral (Omentum): p = 0.03
Ovary: p = 0.07
Whole Blood: p = 0.07
H57Diagnoses - main ICD10: H57 Other disorders of eye and adnexaUK Biobank (UKBB)Neale Lab20181903610043Brain - Substantia nigra: p = 0.00135
Artery - Tibial: p = 0.00308
Brain - Amygdala: p = 0.00342
H18Diagnoses - main ICD10: H18 Other disorders of corneaUK Biobank (UKBB)Neale Lab20182953608993Adipose - Subcutaneous: p = 0.00917
Adipose - Visceral (Omentum): p = 0.04
Thyroid: p = 0.05
F41Diagnoses - main ICD10: F41 Other anxiety disordersUK Biobank (UKBB)Neale Lab20184163607783Artery - Coronary: p = 0.00862
Esophagus - Gastroesophageal Junction: p = 0.00862
Minor Salivary Gland: p = 0.00862
K51Diagnoses - main ICD10: K51 Ulcerative colitisUK Biobank (UKBB)Neale Lab201821433590515Spleen: p = 9.93E-8
Lung: p = 5.98E-6
Small Intestine - Terminal Ileum: p = 6.46E-4
R35Diagnoses - main ICD10: R35 PolyuriaUK Biobank (UKBB)Neale Lab201817733594212Colon - Sigmoid: p = 0.00326
Esophagus - Gastroesophageal Junction: p = 0.00599
Esophagus - Muscularis: p = 0.01
K59Diagnoses - main ICD10: K59 Other functional intestinal disordersUK Biobank (UKBB)Neale Lab201837123574823Brain - Cerebellar Hemisphere: p = 8.51E-4
Esophagus - Gastroesophageal Junction: p = 0.00332
Brain - Cerebellum: p = 0.00454
G57Diagnoses - main ICD10: G57 Mononeuropathies of lower limbUK Biobank (UKBB)Neale Lab201811113600832Spleen: p = 0.02
Brain - Cerebellar Hemisphere: p = 0.04
Adipose - Visceral (Omentum): p = 0.04
C80Diagnoses - main ICD10: C80 Malignant neoplasm without specification of siteUK Biobank (UKBB)Neale Lab20183983607963Liver: p = 0.00398
Adipose - Visceral (Omentum): p = 0.00901
Breast - Mammary Tissue: p = 0.00901
I89Diagnoses - main ICD10: I89 Other non-infective disorders of lymphatic vessels and lymph nodesUK Biobank (UKBB)Neale Lab20181253610693Colon - Sigmoid: p = 0.00561
Esophagus - Gastroesophageal Junction: p = 0.02
Minor Salivary Gland: p = 0.04
R25Diagnoses - main ICD10: R25 Abnormal involuntary movementsUK Biobank (UKBB)Neale Lab20182333609613Nerve - Tibial: p = 0.00623
Artery - Aorta: p = 0.00957
Colon - Transverse: p = 0.03
C79Diagnoses - main ICD10: C79 Secondary malignant neoplasm of other sitesUK Biobank (UKBB)Neale Lab201810993600953Pancreas: p = 4.01E-4
Small Intestine - Terminal Ileum: p = 0.00435
Esophagus - Muscularis: p = 0.02
N88Diagnoses - main ICD10: N88 Other noninflammatory disorders of cervix uteriUK Biobank (UKBB)Neale Lab20184353607592Esophagus - Mucosa: p = 0.01
Skin - Not Sun Exposed (Suprapubic): p = 0.02
Skin - Sun Exposed (Lower leg): p = 0.02
C82Diagnoses - main ICD10: C82 Follicular [nodular] non-Hodgkin's lymphomaUK Biobank (UKBB)Neale Lab20183203608743Lung: p = 1.03E-5
Spleen: p = 1.03E-5
Adipose - Visceral (Omentum): p = 0.00323
K08Diagnoses - main ICD10: K08 Other disorders of teeth and supporting structuresUK Biobank (UKBB)Neale Lab201818383593563Small Intestine - Terminal Ileum: p = 5.6E-4
Kidney - Cortex: p = 0.00404
Esophagus - Gastroesophageal Junction: p = 0.02
R51Diagnoses - main ICD10: R51 HeadacheUK Biobank (UKBB)Neale Lab201842713569233Vagina: p = 0.02
Adipose - Visceral (Omentum): p = 0.02
Pancreas: p = 0.03
G62Diagnoses - main ICD10: G62 Other polyneuropathiesUK Biobank (UKBB)Neale Lab20182923609023Testis: p = 0.00105
Artery - Coronary: p = 0.03
Liver: p = 0.03
M17Diagnoses - main ICD10: M17 Gonarthrosis [arthrosis of knee]UK Biobank (UKBB)Neale Lab2018114973496975Muscle - Skeletal: p = 0.02
Heart - Left Ventricle: p = 0.03
Uterus: p = 0.03
R52Diagnoses - main ICD10: R52 Pain, not elsewhere classifiedUK Biobank (UKBB)Neale Lab20183103608843Adipose - Visceral (Omentum): p = 1.79E-4
Breast - Mammary Tissue: p = 0.00258
Brain - Cerebellum: p = 0.00414
H92Diagnoses - main ICD10: H92 Otalgia and effusion of earUK Biobank (UKBB)Neale Lab20182513609433Liver: p = 0.00444
Stomach: p = 0.02
Pancreas: p = 0.02
R09Diagnoses - main ICD10: R09 Other symptoms and signs involving the circulatory and respiratory systemsUK Biobank (UKBB)Neale Lab20183743608203Spleen: p = 3.08E-6
Whole Blood: p = 0.00719
Lung: p = 0.03
F52Diagnoses - main ICD10: F52 Sexual dysfunction, not caused by organic disorder or diseaseUK Biobank (UKBB)Neale Lab20181213610733Whole Blood: p = 0.0071
Testis: p = 0.01
Small Intestine - Terminal Ileum: p = 0.02
S39Diagnoses - main ICD10: S39 Other and unspecified injuries of abdomen, lower back and pelvisUK Biobank (UKBB)Neale Lab20181953609993Spleen: p = 0.01
Thyroid: p = 0.02
Adipose - Visceral (Omentum): p = 0.02
Z76Diagnoses - main ICD10: Z76 Persons encountering health services in other circumstancesUK Biobank (UKBB)Neale Lab20181183610763Colon - Sigmoid: p = 0.03
Artery - Tibial: p = 0.04
Brain - Caudate (basal ganglia): p = 0.07
H16Diagnoses - main ICD10: H16 KeratitisUK Biobank (UKBB)Neale Lab20181543610403Liver: p = 0.00279
Small Intestine - Terminal Ileum: p = 0.01
Brain - Caudate (basal ganglia): p = 0.01
D89Diagnoses - main ICD10: D89 Other disorders involving the immune mechanism, not elsewhere classifiedUK Biobank (UKBB)Neale Lab20181513610433Lung: p = 0.00154
Liver: p = 0.01
Colon - Transverse: p = 0.02
G56Diagnoses - main ICD10: G56 Mononeuropathies of upper limbUK Biobank (UKBB)Neale Lab201881303530645Lung: p = 1.52E-4
Whole Blood: p = 3.51E-4
Spleen: p = 7.16E-4
K04Diagnoses - main ICD10: K04 Diseases of pulp and periapical tissuesUK Biobank (UKBB)Neale Lab201816093595853Vagina: p = 0.00914
Pituitary: p = 0.01
Kidney - Cortex: p = 0.02
J32Diagnoses - main ICD10: J32 Chronic sinusitisUK Biobank (UKBB)Neale Lab201811793600152Brain - Cerebellar Hemisphere: p = 0.05
Brain - Cerebellum: p = 0.07
Whole Blood: p = 0.08
S46Diagnoses - main ICD10: S46 Injury of muscle and tendon at shoulder and upper arm levelUK Biobank (UKBB)Neale Lab20181413610532Brain - Cerebellum: p = 0.00534
Brain - Putamen (basal ganglia): p = 0.00534
Brain - Caudate (basal ganglia): p = 0.01
C69Diagnoses - main ICD10: C69 Malignant neoplasm of eye and adnexaUK Biobank (UKBB)Neale Lab20181373610572Pancreas: p = 0.02
Minor Salivary Gland: p = 0.04
Brain - Frontal Cortex (BA9): p = 0.05
R32Diagnoses - main ICD10: R32 Unspecified urinary incontinenceUK Biobank (UKBB)Neale Lab20188713603232Brain - Cerebellar Hemisphere: p = 0.0014
Brain - Cerebellum: p = 0.0014
Esophagus - Mucosa: p = 0.00511
D48Diagnoses - main ICD10: D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sitesUK Biobank (UKBB)Neale Lab20185443606503Spleen: p = 0.00228
Brain - Cerebellar Hemisphere: p = 0.03
Brain - Cerebellum: p = 0.03
C73Diagnoses - main ICD10: C73 Malignant neoplasm of thyroid glandUK Biobank (UKBB)Neale Lab20182783609163Lung: p = 0.00153
Adrenal Gland: p = 0.00404
Small Intestine - Terminal Ileum: p = 0.04
Z12Diagnoses - main ICD10: Z12 Special screening examination for neoplasmsUK Biobank (UKBB)Neale Lab201841523570423Pancreas: p = 0.03
Skin - Sun Exposed (Lower leg): p = 0.03
Colon - Sigmoid: p = 0.04
R07Diagnoses - main ICD10: R07 Pain in throat and chestUK Biobank (UKBB)Neale Lab2018245303366644Kidney - Cortex: p = 8.04E-4
Nerve - Tibial: p = 0.00872
Whole Blood: p = 0.01
L60Diagnoses - main ICD10: L60 Nail disordersUK Biobank (UKBB)Neale Lab20188863603083Colon - Sigmoid: p = 0.02
Vagina: p = 0.04
Brain - Frontal Cortex (BA9): p = 0.04
L08Diagnoses - main ICD10: L08 Other local infections of skin and subcutaneous tissueUK Biobank (UKBB)Neale Lab20184623607322Artery - Tibial: p = 0.02
Testis: p = 0.02
Stomach: p = 0.04
I51Diagnoses - main ICD10: I51 Complications and ill-defined descriptions of heart diseaseUK Biobank (UKBB)Neale Lab20182703609243Prostate: p = 5.0E-4
Lung: p = 0.00135
Artery - Aorta: p = 0.00342
K20Diagnoses - main ICD10: K20 OesophagitisUK Biobank (UKBB)Neale Lab201847993563953Adipose - Visceral (Omentum): p = 0.02
Skin - Sun Exposed (Lower leg): p = 0.02
Brain - Cerebellar Hemisphere: p = 0.03
C64Diagnoses - main ICD10: C64 Malignant neoplasm of kidney, except renal pelvisUK Biobank (UKBB)Neale Lab20187013604933Esophagus - Muscularis: p = 0.00983
Adrenal Gland: p = 0.04
Testis: p = 0.04
S60Diagnoses - main ICD10: S60 Superficial injury of wrist and handUK Biobank (UKBB)Neale Lab20181593610353Pituitary: p = 0.00864
Heart - Atrial Appendage: p = 0.01
Thyroid: p = 0.01
Z30Diagnoses - main ICD10: Z30 Contraceptive managementUK Biobank (UKBB)Neale Lab201863923548023Whole Blood: p = 0.005
Skin - Not Sun Exposed (Suprapubic): p = 0.00795
Stomach: p = 0.00874
R30Diagnoses - main ICD10: R30 Pain associated with micturitionUK Biobank (UKBB)Neale Lab20183593608352Skin - Not Sun Exposed (Suprapubic): p = 0.00262
Muscle - Skeletal: p = 0.00668
Skin - Sun Exposed (Lower leg): p = 0.01
I60Diagnoses - main ICD10: I60 Subarachnoid haemorrhageUK Biobank (UKBB)Neale Lab20186423605523Artery - Tibial: p = 5.08E-4
Artery - Coronary: p = 0.00887
Colon - Transverse: p = 0.02
S06Diagnoses - main ICD10: S06 Intracranial injuryUK Biobank (UKBB)Neale Lab20188053603893Artery - Tibial: p = 0.00562
Spleen: p = 0.00833
Esophagus - Gastroesophageal Junction: p = 0.02
K37Diagnoses - main ICD10: K37 Unspecified appendicitisUK Biobank (UKBB)Neale Lab20183553608393Lung: p = 0.00936
Adipose - Subcutaneous: p = 0.01
Esophagus - Gastroesophageal Junction: p = 0.01
H73Diagnoses - main ICD10: H73 Other disorders of tympanic membraneUK Biobank (UKBB)Neale Lab20181623610323Liver: p = 0.00115
Brain - Substantia nigra: p = 0.00471
Brain - Spinal cord (cervical c-1): p = 0.01
B34Diagnoses - main ICD10: B34 Viral infection of unspecified siteUK Biobank (UKBB)Neale Lab20189333602613Esophagus - Mucosa: p = 2.97E-6
Vagina: p = 1.71E-4
Ovary: p = 0.00447
Z85Diagnoses - main ICD10: Z85 Personal history of malignant neoplasmUK Biobank (UKBB)Neale Lab20182383609563Ovary: p = 0.01
Colon - Sigmoid: p = 0.02
Skin - Sun Exposed (Lower leg): p = 0.02
I22Diagnoses - main ICD10: I22 Subsequent myocardial infarctionUK Biobank (UKBB)Neale Lab20184643607303Artery - Coronary: p = 4.09E-4
Artery - Aorta: p = 0.00559
Heart - Atrial Appendage: p = 0.00563
D69Diagnoses - main ICD10: D69 Purpura and other haemorrhagic conditionsUK Biobank (UKBB)Neale Lab20184103607842Liver: p = 0.00267
Brain - Cerebellar Hemisphere: p = 0.01
Muscle - Skeletal: p = 0.01
S81Diagnoses - main ICD10: S81 Open wound of lower legUK Biobank (UKBB)Neale Lab20182873609073Adipose - Subcutaneous: p = 0.00513
Brain - Cerebellum: p = 0.00795
Nerve - Tibial: p = 0.02
J69Diagnoses - main ICD10: J69 Pneumonitis due to solids and liquidsUK Biobank (UKBB)Neale Lab20181433610513Brain - Nucleus accumbens (basal ganglia): p = 0.02
Artery - Tibial: p = 0.02
Skin - Not Sun Exposed (Suprapubic): p = 0.06
J31Diagnoses - main ICD10: J31 Chronic rhinitis, nasopharyngitis and pharyngitisUK Biobank (UKBB)Neale Lab20182913609033Vagina: p = 2.83E-4
Esophagus - Mucosa: p = 0.00308
Whole Blood: p = 0.02
F33Diagnoses - main ICD10: F33 Recurrent depressive disorderUK Biobank (UKBB)Neale Lab20182933609013Pancreas: p = 0.0071
Spleen: p = 0.02
Lung: p = 0.04
Z80Diagnoses - main ICD10: Z80 Family history of malignant neoplasmUK Biobank (UKBB)Neale Lab20183773608172Brain - Caudate (basal ganglia): p = 0.0013
Brain - Putamen (basal ganglia): p = 0.0035
Brain - Anterior cingulate cortex (BA24): p = 0.01
C16Diagnoses - main ICD10: C16 Malignant neoplasm of stomachUK Biobank (UKBB)Neale Lab20183883608062Colon - Sigmoid: p = 0.02
Lung: p = 0.03
Breast - Mammary Tissue: p = 0.07
M53Diagnoses - main ICD10: M53 Other dorsopathies, not elsewhere classifiedUK Biobank (UKBB)Neale Lab20183423608523Heart - Left Ventricle: p = 0.01
Kidney - Cortex: p = 0.02
Heart - Atrial Appendage: p = 0.03
Z50Diagnoses - main ICD10: Z50 Care involving use of rehabilitation proceduresUK Biobank (UKBB)Neale Lab20182183609763Brain - Cortex: p = 0.04
Brain - Frontal Cortex (BA9): p = 0.07
Muscle - Skeletal: p = 0.07
Z34Diagnoses - main ICD10: Z34 Supervision of normal pregnancyUK Biobank (UKBB)Neale Lab20187313604633Kidney - Cortex: p = 0.01
Liver: p = 0.02
Lung: p = 0.02
D50Diagnoses - main ICD10: D50 Iron deficiency anaemiaUK Biobank (UKBB)Neale Lab201832223579724Spleen: p = 3.43E-6
Lung: p = 5.18E-5
Colon - Sigmoid: p = 0.02
M77Diagnoses - main ICD10: M77 Other enthesopathiesUK Biobank (UKBB)Neale Lab20189953601993Whole Blood: p = 0.00308
Pancreas: p = 0.01
Small Intestine - Terminal Ileum: p = 0.03
I10Diagnoses - main ICD10: I10 Essential (primary) hypertensionUK Biobank (UKBB)Neale Lab20187873604073Spleen: p = 0.01
Lung: p = 0.02
Adipose - Subcutaneous: p = 0.02
I78Diagnoses - main ICD10: I78 Diseases of capillariesUK Biobank (UKBB)Neale Lab20182903609043Brain - Spinal cord (cervical c-1): p = 0.00277
Adipose - Visceral (Omentum): p = 0.00671
Brain - Amygdala: p = 0.00843
H01Diagnoses - main ICD10: H01 Other inflammation of eyelidUK Biobank (UKBB)Neale Lab20181523610423Esophagus - Mucosa: p = 2.24E-4
Small Intestine - Terminal Ileum: p = 0.0087
Stomach: p = 0.00874
K00Diagnoses - main ICD10: K00 Disorders of tooth development and eruptionUK Biobank (UKBB)Neale Lab20181233610713Artery - Tibial: p = 0.00255
Muscle - Skeletal: p = 0.00913
Heart - Left Ventricle: p = 0.02
T84Diagnoses - main ICD10: T84 Complications of internal orthopaedic prosthetic devices, implants and graftsUK Biobank (UKBB)Neale Lab201837193574753Esophagus - Mucosa: p = 0.00811
Minor Salivary Gland: p = 0.02
Brain - Spinal cord (cervical c-1): p = 0.02
S02Diagnoses - main ICD10: S02 Fracture of skull and facial bonesUK Biobank (UKBB)Neale Lab201813513598432Esophagus - Gastroesophageal Junction: p = 0.00564
Stomach: p = 0.00603
Pancreas: p = 0.01
K60Diagnoses - main ICD10: K60 Fissure and fistula of anal and rectal regionsUK Biobank (UKBB)Neale Lab201821093590853Brain - Substantia nigra: p = 0.01
Adipose - Subcutaneous: p = 0.03
Breast - Mammary Tissue: p = 0.03
S66Diagnoses - main ICD10: S66 Injury of muscle and tendon at wrist and hand levelUK Biobank (UKBB)Neale Lab20187893604053Ovary: p = 1.65E-4
Uterus: p = 1.65E-4
Heart - Left Ventricle: p = 0.03
S70Diagnoses - main ICD10: S70 Superficial injury of hip and thighUK Biobank (UKBB)Neale Lab20181293610652Skin - Not Sun Exposed (Suprapubic): p = 0.00561
Skin - Sun Exposed (Lower leg): p = 0.02
Colon - Sigmoid: p = 0.04
R10Diagnoses - main ICD10: R10 Abdominal and pelvic painUK Biobank (UKBB)Neale Lab2018202403409544Brain - Substantia nigra: p = 0.00382
Brain - Frontal Cortex (BA9): p = 0.00708
Lung: p = 0.00708
Z87Diagnoses - main ICD10: Z87 Personal history of other diseases and conditionsUK Biobank (UKBB)Neale Lab20182343609602Esophagus - Mucosa: p = 0.00705
Skin - Not Sun Exposed (Suprapubic): p = 0.00705
Adipose - Subcutaneous: p = 0.02
R15Diagnoses - main ICD10: R15 Faecal incontinenceUK Biobank (UKBB)Neale Lab20189103602843Skin - Not Sun Exposed (Suprapubic): p = 0.00563
Skin - Sun Exposed (Lower leg): p = 0.02
Colon - Transverse: p = 0.03
N28Diagnoses - main ICD10: N28 Other disorders of kidney and ureter, not elsewhere classifiedUK Biobank (UKBB)Neale Lab20184523607422Liver: p = 0.01
Colon - Sigmoid: p = 0.04
Adipose - Subcutaneous: p = 0.05
D39Diagnoses - main ICD10: D39 Neoplasm of uncertain or unknown behaviour of female genital organsUK Biobank (UKBB)Neale Lab20181253610693Colon - Transverse: p = 0.00509
Brain - Caudate (basal ganglia): p = 0.00907
Prostate: p = 0.01
O26Diagnoses - main ICD10: O26 Maternal care for other conditions predominantly related to pregnancyUK Biobank (UKBB)Neale Lab201812893599052Esophagus - Mucosa: p = 0.00511
Whole Blood: p = 0.02
Colon - Transverse: p = 0.06
L03Diagnoses - main ICD10: L03 CellulitisUK Biobank (UKBB)Neale Lab201842473569473Pancreas: p = 0.00523
Thyroid: p = 0.01
Prostate: p = 0.02
I73Diagnoses - main ICD10: I73 Other peripheral vascular diseasesUK Biobank (UKBB)Neale Lab20186663605283Esophagus - Mucosa: p = 0.00978
Whole Blood: p = 0.01
Nerve - Tibial: p = 0.02
H74Diagnoses - main ICD10: H74 Other disorders of middle ear and mastoidUK Biobank (UKBB)Neale Lab20182333609613Small Intestine - Terminal Ileum: p = 0.00649
Spleen: p = 0.03
Brain - Caudate (basal ganglia): p = 0.07
D07Diagnoses - main ICD10: D07 Carcinoma in situ of other and unspecified genital organsUK Biobank (UKBB)Neale Lab20183363608583Skin - Sun Exposed (Lower leg): p = 0.00107
Whole Blood: p = 0.00242
Skin - Not Sun Exposed (Suprapubic): p = 0.0027
I83Diagnoses - main ICD10: I83 Varicose veins of lower extremitiesUK Biobank (UKBB)Neale Lab201887633524315Esophagus - Gastroesophageal Junction: p = 3.69E-4
Whole Blood: p = 0.00131
Lung: p = 0.00547
M20Diagnoses - main ICD10: M20 Acquired deformities of fingers and toesUK Biobank (UKBB)Neale Lab201877733534215Artery - Tibial: p = 0.00597
Muscle - Skeletal: p = 0.00849
Brain - Cerebellar Hemisphere: p = 0.02
R17Diagnoses - main ICD10: R17 Unspecified jaundiceUK Biobank (UKBB)Neale Lab20183323608623Pituitary: p = 2.92E-4
Lung: p = 6.8E-4
Stomach: p = 0.00662
M87Diagnoses - main ICD10: M87 OsteonecrosisUK Biobank (UKBB)Neale Lab20181913610033Small Intestine - Terminal Ileum: p = 0.0083
Brain - Cortex: p = 0.00984
Brain - Putamen (basal ganglia): p = 0.00984
B07Diagnoses - main ICD10: B07 Viral wartsUK Biobank (UKBB)Neale Lab20184373607572Brain - Spinal cord (cervical c-1): p = 0.00259
Brain - Caudate (basal ganglia): p = 0.00356
Brain - Nucleus accumbens (basal ganglia): p = 0.00356
D37Diagnoses - main ICD10: D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organsUK Biobank (UKBB)Neale Lab20187363604582Brain - Nucleus accumbens (basal ganglia): p = 3.06E-4
Brain - Cortex: p = 8.85E-4
Brain - Frontal Cortex (BA9): p = 8.85E-4
T43Diagnoses - main ICD10: T43 Poisoning by psychotropic drugs, not elsewhere classifiedUK Biobank (UKBB)Neale Lab20186923605023Adipose - Subcutaneous: p = 0.00299
Esophagus - Mucosa: p = 0.00308
Pancreas: p = 0.03
L92Diagnoses - main ICD10: L92 Granulomatous disorders of skin and subcutaneous tissueUK Biobank (UKBB)Neale Lab20183383608563Prostate: p = 7.42E-4
Skin - Sun Exposed (Lower leg): p = 0.00678
Skin - Not Sun Exposed (Suprapubic): p = 0.03
R60Diagnoses - main ICD10: R60 Oedema, not elsewhere classifiedUK Biobank (UKBB)Neale Lab20182273609672Lung: p = 0.01
Uterus: p = 0.02
Muscle - Skeletal: p = 0.05
C43Diagnoses - main ICD10: C43 Malignant melanoma of skinUK Biobank (UKBB)Neale Lab201816723595225Pituitary: p = 0.00153
Adipose - Subcutaneous: p = 0.02
Colon - Sigmoid: p = 0.02
G37Diagnoses - main ICD10: G37 Other demyelinating diseases of central nervous systemUK Biobank (UKBB)Neale Lab20182003609943Brain - Hypothalamus: p = 0.0012
Brain - Substantia nigra: p = 0.0012
Spleen: p = 0.00324
E11Diagnoses - main ICD10: E11 Non-insulin-dependent diabetes mellitusUK Biobank (UKBB)Neale Lab20187053604893Lung: p = 3.26E-4
Adipose - Subcutaneous: p = 0.03
Breast - Mammary Tissue: p = 0.03
Z09Diagnoses - main ICD10: Z09 Follow-up examination after treatment for conditions other than malignant neoplasmsUK Biobank (UKBB)Neale Lab201884643527303Uterus: p = 0.00574
Artery - Tibial: p = 0.02
Artery - Aorta: p = 0.03
K21Diagnoses - main ICD10: K21 Gastro-oesophageal reflux diseaseUK Biobank (UKBB)Neale Lab2018107433504513Vagina: p = 0.01
Uterus: p = 0.02
Colon - Sigmoid: p = 0.05
N61Diagnoses - main ICD10: N61 Inflammatory disorders of breastUK Biobank (UKBB)Neale Lab20183433608513Skin - Sun Exposed (Lower leg): p = 0.00453
Muscle - Skeletal: p = 0.00502
Vagina: p = 0.01
D44Diagnoses - main ICD10: D44 Neoplasm of uncertain or unknown behaviour of endocrine glandsUK Biobank (UKBB)Neale Lab20181133610813Brain - Cerebellar Hemisphere: p = 0.00243
Artery - Aorta: p = 0.00265
Brain - Cerebellum: p = 0.00599
M31Diagnoses - main ICD10: M31 Other necrotising vasculopathiesUK Biobank (UKBB)Neale Lab20183263608683Brain - Cortex: p = 0.0012
Spleen: p = 0.00199
Brain - Caudate (basal ganglia): p = 0.00319
D12Diagnoses - main ICD10: D12 Benign neoplasm of colon, rectum, anus and anal canalUK Biobank (UKBB)Neale Lab201888773523175Esophagus - Gastroesophageal Junction: p = 0.00121
Vagina: p = 0.00121
Esophagus - Mucosa: p = 0.00231
H91Diagnoses - main ICD10: H91 Other hearing lossUK Biobank (UKBB)Neale Lab20183903608043Heart - Left Ventricle: p = 0.00843
Skin - Not Sun Exposed (Suprapubic): p = 0.03
Colon - Transverse: p = 0.05
H71Diagnoses - main ICD10: H71 Cholesteatoma of middle earUK Biobank (UKBB)Neale Lab20183303608643Whole Blood: p = 1.65E-4
Artery - Aorta: p = 0.00182
Colon - Sigmoid: p = 0.00453
G51Diagnoses - main ICD10: G51 Facial nerve disordersUK Biobank (UKBB)Neale Lab20183753608193Minor Salivary Gland: p = 0.01
Colon - Sigmoid: p = 0.02
Testis: p = 0.03
M43Diagnoses - main ICD10: M43 Other deforming dorsopathiesUK Biobank (UKBB)Neale Lab20186173605773Prostate: p = 0.00885
Esophagus - Gastroesophageal Junction: p = 0.01
Pituitary: p = 0.01
M84Diagnoses - main ICD10: M84 Disorders of continuity of boneUK Biobank (UKBB)Neale Lab201810653601293Whole Blood: p = 0.02
Muscle - Skeletal: p = 0.03
Pancreas: p = 0.03
N43Diagnoses - main ICD10: N43 Hydrocele and spermatoceleUK Biobank (UKBB)Neale Lab20188843603103Spleen: p = 0.01
Small Intestine - Terminal Ileum: p = 0.05
Stomach: p = 0.08
K74Diagnoses - main ICD10: K74 Fibrosis and cirrhosis of liverUK Biobank (UKBB)Neale Lab20182523609423Artery - Tibial: p = 0.00534
Liver: p = 0.03
Uterus: p = 0.03
S61Diagnoses - main ICD10: S61 Open wound of wrist and handUK Biobank (UKBB)Neale Lab201818653593293Stomach: p = 0.00671
Testis: p = 0.02
Liver: p = 0.03
H60Diagnoses - main ICD10: H60 Otitis externaUK Biobank (UKBB)Neale Lab20183023608922Artery - Aorta: p = 0.01
Whole Blood: p = 0.02
Spleen: p = 0.05
Z46Diagnoses - main ICD10: Z46 Fitting and adjustment of other devicesUK Biobank (UKBB)Neale Lab201836143575803Liver: p = 0.03
Minor Salivary Gland: p = 0.03
Kidney - Cortex: p = 0.06
K75Diagnoses - main ICD10: K75 Other inflammatory liver diseasesUK Biobank (UKBB)Neale Lab20183023608923Lung: p = 0.00214
Whole Blood: p = 0.00845
Spleen: p = 0.03
M67Diagnoses - main ICD10: M67 Other disorders of synovium and tendonUK Biobank (UKBB)Neale Lab201826133585813Colon - Transverse: p = 0.00207
Kidney - Cortex: p = 0.00995
Uterus: p = 0.00995
M70Diagnoses - main ICD10: M70 Soft tissue disorders related to use, overuse and pressureUK Biobank (UKBB)Neale Lab201810793601153Artery - Aorta: p = 0.00143
Artery - Coronary: p = 0.00349
Artery - Tibial: p = 0.00349
K92Diagnoses - main ICD10: K92 Other diseases of digestive systemUK Biobank (UKBB)Neale Lab201850193561752Skin - Sun Exposed (Lower leg): p = 0.01
Small Intestine - Terminal Ileum: p = 0.02
Skin - Not Sun Exposed (Suprapubic): p = 0.02
O70Diagnoses - main ICD10: O70 Perineal laceration during deliveryUK Biobank (UKBB)Neale Lab201830773581173Prostate: p = 0.00766
Testis: p = 0.02
Colon - Sigmoid: p = 0.07
J46Diagnoses - main ICD10: J46 Status asthmaticusUK Biobank (UKBB)Neale Lab20181803610143Muscle - Skeletal: p = 0.00978
Whole Blood: p = 0.02
Lung: p = 0.06
Z01Diagnoses - main ICD10: Z01 Other special examinations and investigations of persons without complaint or reported diagnosisUK Biobank (UKBB)Neale Lab201813703598242Esophagus - Mucosa: p = 0.02
Brain - Cerebellar Hemisphere: p = 0.02
Esophagus - Gastroesophageal Junction: p = 0.02
C67Diagnoses - main ICD10: C67 Malignant neoplasm of bladderUK Biobank (UKBB)Neale Lab201815543596403Muscle - Skeletal: p = 0.00816
Esophagus - Mucosa: p = 0.02
Skin - Not Sun Exposed (Suprapubic): p = 0.02
K07Diagnoses - main ICD10: K07 Dentofacial anomalies [including malocclusion]UK Biobank (UKBB)Neale Lab20184103607843Whole Blood: p = 0.02
Muscle - Skeletal: p = 0.03
Pituitary: p = 0.06
E83Diagnoses - main ICD10: E83 Disorders of mineral metabolismUK Biobank (UKBB)Neale Lab20187583604365Spleen: p = 1.03E-4
Whole Blood: p = 5.71E-4
Uterus: p = 0.00339
E23Diagnoses - main ICD10: E23 Hypofunction and other disorders of pituitary glandUK Biobank (UKBB)Neale Lab20181733610212Adipose - Subcutaneous: p = 0.00932
Uterus: p = 0.02
Adipose - Visceral (Omentum): p = 0.03
K86Diagnoses - main ICD10: K86 Other diseases of pancreasUK Biobank (UKBB)Neale Lab20185213606733Adipose - Visceral (Omentum): p = 0.00569
Nerve - Tibial: p = 0.00889
Breast - Mammary Tissue: p = 0.01
R47Diagnoses - main ICD10: R47 Speech disturbances, not elsewhere classifiedUK Biobank (UKBB)Neale Lab20182993608953Spleen: p = 6.07E-4
Breast - Mammary Tissue: p = 0.00318
Adipose - Subcutaneous: p = 0.00515
K61Diagnoses - main ICD10: K61 Abscess of anal and rectal regionsUK Biobank (UKBB)Neale Lab201810533601413Liver: p = 0.00279
Ovary: p = 0.00696
Pancreas: p = 0.03
O75Diagnoses - main ICD10: O75 Other complications of labour and delivery, not elsewhere classifiedUK Biobank (UKBB)Neale Lab20182083609863Pancreas: p = 0.00765
Breast - Mammary Tissue: p = 0.02
Kidney - Cortex: p = 0.03
O63Diagnoses - main ICD10: O63 Long labourUK Biobank (UKBB)Neale Lab201810603601342Testis: p = 0.00743
Brain - Hypothalamus: p = 0.02
Stomach: p = 0.04
M89Diagnoses - main ICD10: M89 Other disorders of boneUK Biobank (UKBB)Neale Lab20187923604023Heart - Atrial Appendage: p = 1.46E-4
Heart - Left Ventricle: p = 0.00721
Lung: p = 0.02
C90Diagnoses - main ICD10: C90 Multiple myeloma and malignant plasma cell neoplasmsUK Biobank (UKBB)Neale Lab20184013607933Adrenal Gland: p = 0.00874
Minor Salivary Gland: p = 0.00874
Colon - Transverse: p = 0.01
O62Diagnoses - main ICD10: O62 Abnormalities of forces of labourUK Biobank (UKBB)Neale Lab20181803610142Artery - Aorta: p = 0.00562
Artery - Tibial: p = 0.00562
Muscle - Skeletal: p = 0.00597
N71Diagnoses - main ICD10: N71 Inflammatory disease of uterus, except cervixUK Biobank (UKBB)Neale Lab20181263610683Esophagus - Gastroesophageal Junction: p = 0.03
Adipose - Subcutaneous: p = 0.06
Adipose - Visceral (Omentum): p = 0.06
S86Diagnoses - main ICD10: S86 Injury of muscle and tendon at lower leg levelUK Biobank (UKBB)Neale Lab20186673605273Adipose - Subcutaneous: p = 0.00926
Artery - Coronary: p = 0.00926
Heart - Atrial Appendage: p = 0.02
C01Diagnoses - main ICD10: C01 Malignant neoplasm of base of tongueUK Biobank (UKBB)Neale Lab20181023610923Ovary: p = 0.02
Esophagus - Mucosa: p = 0.06
Skin - Not Sun Exposed (Suprapubic): p = 0.06
L29Diagnoses - main ICD10: L29 PruritusUK Biobank (UKBB)Neale Lab20182523609422Pancreas: p = 0.00106
Pituitary: p = 0.0018
Liver: p = 0.02
Z11Diagnoses - main ICD10: Z11 Special screening examination for infectious and parasitic diseasesUK Biobank (UKBB)Neale Lab20182513609433Artery - Tibial: p = 0.01
Minor Salivary Gland: p = 0.03
Breast - Mammary Tissue: p = 0.05
S52Diagnoses - main ICD10: S52 Fracture of forearmUK Biobank (UKBB)Neale Lab201850803561143Uterus: p = 0.00726
Adipose - Visceral (Omentum): p = 0.02
Breast - Mammary Tissue: p = 0.03
O99Diagnoses - main ICD10: O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperiumUK Biobank (UKBB)Neale Lab20185673606273Small Intestine - Terminal Ileum: p = 0.02
Brain - Amygdala: p = 0.03
Whole Blood: p = 0.03
D41Diagnoses - main ICD10: D41 Neoplasm of uncertain or unknown behaviour of urinary organsUK Biobank (UKBB)Neale Lab20185243606703Lung: p = 0.0039
Colon - Sigmoid: p = 0.02
Esophagus - Gastroesophageal Junction: p = 0.02
C61Diagnoses - main ICD10: C61 Malignant neoplasm of prostateUK Biobank (UKBB)Neale Lab201843423568525Colon - Transverse: p = 9.3E-4
Minor Salivary Gland: p = 0.00112
Pancreas: p = 0.00112
D06Diagnoses - main ICD10: D06 Carcinoma in situ of cervix uteriUK Biobank (UKBB)Neale Lab20184503607443Minor Salivary Gland: p = 0.00384
Colon - Transverse: p = 0.00935
Brain - Amygdala: p = 0.02
M86Diagnoses - main ICD10: M86 OsteomyelitisUK Biobank (UKBB)Neale Lab20182483609463Esophagus - Mucosa: p = 0.02
Spleen: p = 0.02
Esophagus - Gastroesophageal Junction: p = 0.04
I84Diagnoses - main ICD10: I84 HaemorrhoidsUK Biobank (UKBB)Neale Lab2018121023490924Artery - Coronary: p = 4.94E-4
Artery - Tibial: p = 0.00122
Artery - Aorta: p = 0.00286
R87Diagnoses - main ICD10: R87 Abnormal findings in specimens from female genital organsUK Biobank (UKBB)Neale Lab201810843601102Stomach: p = 0.00929
Lung: p = 0.03
Testis: p = 0.03
N19Diagnoses - main ICD10: N19 Unspecified renal failureUK Biobank (UKBB)Neale Lab20181643610303Adipose - Visceral (Omentum): p = 0.00236
Breast - Mammary Tissue: p = 0.01
Skin - Not Sun Exposed (Suprapubic): p = 0.02
C62Diagnoses - main ICD10: C62 Malignant neoplasm of testisUK Biobank (UKBB)Neale Lab20182213609733Vagina: p = 0.02
Adipose - Visceral (Omentum): p = 0.03
Esophagus - Mucosa: p = 0.03
I08Diagnoses - main ICD10: I08 Multiple valve diseasesUK Biobank (UKBB)Neale Lab20182503609443Heart - Atrial Appendage: p = 0.00478
Kidney - Cortex: p = 0.01
Heart - Left Ventricle: p = 0.02
Z36Diagnoses - main ICD10: Z36 Antenatal screeningUK Biobank (UKBB)Neale Lab20188413603533Minor Salivary Gland: p = 0.00385
Whole Blood: p = 0.03
Vagina: p = 0.03
G44Diagnoses - main ICD10: G44 Other headache syndromesUK Biobank (UKBB)Neale Lab20183073608873Artery - Aorta: p = 0.00222
Small Intestine - Terminal Ileum: p = 0.00223
Brain - Substantia nigra: p = 0.03
M66Diagnoses - main ICD10: M66 Spontaneous rupture of synovium and tendonUK Biobank (UKBB)Neale Lab20183883608063Muscle - Skeletal: p = 0.00543
Liver: p = 0.02
Small Intestine - Terminal Ileum: p = 0.05
Z00Diagnoses - main ICD10: Z00 General examination and investigation of persons without complaint or reported diagnosisUK Biobank (UKBB)Neale Lab20182493609453Vagina: p = 0.01
Liver: p = 0.02
Esophagus - Mucosa: p = 0.03
N84Diagnoses - main ICD10: N84 Polyp of female genital tractUK Biobank (UKBB)Neale Lab201869863542084Esophagus - Gastroesophageal Junction: p = 3.57E-4
Esophagus - Muscularis: p = 0.00224
Colon - Sigmoid: p = 0.01
J38Diagnoses - main ICD10: J38 Diseases of vocal cords and larynx, not elsewhere classifiedUK Biobank (UKBB)Neale Lab201811683600263Esophagus - Gastroesophageal Junction: p = 0.00396
Breast - Mammary Tissue: p = 0.01
Artery - Coronary: p = 0.02
L57Diagnoses - main ICD10: L57 Skin changes due to chronic exposure to nonionising radiationUK Biobank (UKBB)Neale Lab201814473597474Kidney - Cortex: p = 0.00414
Esophagus - Mucosa: p = 0.02
Pituitary: p = 0.03
D28Diagnoses - main ICD10: D28 Benign neoplasm of other and unspecified female genital organsUK Biobank (UKBB)Neale Lab20181323610622Heart - Atrial Appendage: p = 0.01
Minor Salivary Gland: p = 0.04
Artery - Coronary: p = 0.04
N42Diagnoses - main ICD10: N42 Other disorders of prostateUK Biobank (UKBB)Neale Lab20186233605713Spleen: p = 1.7E-4
Brain - Amygdala: p = 0.01
Breast - Mammary Tissue: p = 0.01
M45Diagnoses - main ICD10: M45 Ankylosing spondylitisUK Biobank (UKBB)Neale Lab20181463610485Whole Blood: p = 2.19E-5
Spleen: p = 3.57E-4
Lung: p = 6.07E-4
T79Diagnoses - main ICD10: T79 Certain early complications of trauma, not elsewhere classifiedUK Biobank (UKBB)Neale Lab20182053609893Pancreas: p = 0.02
Stomach: p = 0.07
Small Intestine - Terminal Ileum: p = 0.08
N90Diagnoses - main ICD10: N90 Other noninflammatory disorders of vulva and perineumUK Biobank (UKBB)Neale Lab201810773601173Spleen: p = 0.01
Breast - Mammary Tissue: p = 0.06
Adipose - Subcutaneous: p = 0.11
C53Diagnoses - main ICD10: C53 Malignant neoplasm of cervix uteriUK Biobank (UKBB)Neale Lab20181923610023Brain - Amygdala: p = 0.00626
Brain - Substantia nigra: p = 0.00626
Thyroid: p = 0.01
R22Diagnoses - main ICD10: R22 Localised swelling, mass and lump of skin and subcutaneous tissueUK Biobank (UKBB)Neale Lab201813583598363Esophagus - Gastroesophageal Junction: p = 0.00109
Esophagus - Muscularis: p = 0.00482
Nerve - Tibial: p = 0.01
D16Diagnoses - main ICD10: D16 Benign neoplasm of bone and articular cartilageUK Biobank (UKBB)Neale Lab20182113609832Adipose - Subcutaneous: p = 0.03
Colon - Sigmoid: p = 0.04
Adrenal Gland: p = 0.04
D13Diagnoses - main ICD10: D13 Benign neoplasm of other and ill-defined parts of digestive systemUK Biobank (UKBB)Neale Lab20186223605722Uterus: p = 0.00366
Pituitary: p = 0.01
Artery - Coronary: p = 0.01
A87Diagnoses - main ICD10: A87 Viral meningitisUK Biobank (UKBB)Neale Lab20181163610783Artery - Tibial: p = 0.02
Adipose - Visceral (Omentum): p = 0.04
Artery - Aorta: p = 0.05
D61Diagnoses - main ICD10: D61 Other aplastic anaemiasUK Biobank (UKBB)Neale Lab20181273610672Pancreas: p = 8.29E-4
Esophagus - Gastroesophageal Junction: p = 0.00299
Ovary: p = 0.00486
O72Diagnoses - main ICD10: O72 Postpartum haemorrhageUK Biobank (UKBB)Neale Lab20183073608873Brain - Frontal Cortex (BA9): p = 0.01
Brain - Cortex: p = 0.02
Adrenal Gland: p = 0.02
S27Diagnoses - main ICD10: S27 Injury of other and unspecified intrathoracic organsUK Biobank (UKBB)Neale Lab20182433609513Liver: p = 0.03
Adipose - Visceral (Omentum): p = 0.03
Brain - Hippocampus: p = 0.03
I20Diagnoses - main ICD10: I20 Angina pectorisUK Biobank (UKBB)Neale Lab201862463549484Heart - Atrial Appendage: p = 1.06E-5
Artery - Coronary: p = 0.00139
Artery - Aorta: p = 0.00419
E14Diagnoses - main ICD10: E14 Unspecified diabetes mellitusUK Biobank (UKBB)Neale Lab20182243609705Lung: p = 1.84E-5
Spleen: p = 0.00401
Liver: p = 0.00841
M21Diagnoses - main ICD10: M21 Other acquired deformities of limbsUK Biobank (UKBB)Neale Lab20185883606063Skin - Sun Exposed (Lower leg): p = 0.00745
Colon - Sigmoid: p = 0.04
Skin - Not Sun Exposed (Suprapubic): p = 0.04
C85Diagnoses - main ICD10: C85 Other and unspecified types of non-Hodgkin's lymphomaUK Biobank (UKBB)Neale Lab20187623604323Whole Blood: p = 0.00284
Spleen: p = 0.03
Muscle - Skeletal: p = 0.05
J98Diagnoses - main ICD10: J98 Other respiratory disordersUK Biobank (UKBB)Neale Lab20185653606293Liver: p = 1.61E-4
Small Intestine - Terminal Ileum: p = 0.01
Spleen: p = 0.02
R14Diagnoses - main ICD10: R14 Flatulence and related conditionsUK Biobank (UKBB)Neale Lab20183313608633Skin - Not Sun Exposed (Suprapubic): p = 0.00296
Skin - Sun Exposed (Lower leg): p = 0.00296
Brain - Spinal cord (cervical c-1): p = 0.02
S72Diagnoses - main ICD10: S72 Fracture of femurUK Biobank (UKBB)Neale Lab201818033593913Adrenal Gland: p = 0.00246
Testis: p = 0.00591
Vagina: p = 0.02
S69Diagnoses - main ICD10: S69 Other and unspecified injuries of wrist and handUK Biobank (UKBB)Neale Lab20181063610883Breast - Mammary Tissue: p = 0.00744
Colon - Transverse: p = 0.04
Pituitary: p = 0.04
L82Diagnoses - main ICD10: L82 Seborrhoeic keratosisUK Biobank (UKBB)Neale Lab201820313591633Skin - Not Sun Exposed (Suprapubic): p = 0.03
Spleen: p = 0.03
Kidney - Cortex: p = 0.03
I82Diagnoses - main ICD10: I82 Other venous embolism and thrombosisUK Biobank (UKBB)Neale Lab20181453610493Adipose - Visceral (Omentum): p = 0.07
Pancreas: p = 0.07
Whole Blood: p = 0.07
H05Diagnoses - main ICD10: H05 Disorders of orbitUK Biobank (UKBB)Neale Lab20181423610522Adrenal Gland: p = 0.02
Brain - Cerebellar Hemisphere: p = 0.04
Stomach: p = 0.04
G40Diagnoses - main ICD10: G40 EpilepsyUK Biobank (UKBB)Neale Lab20187953603993Colon - Transverse: p = 0.00167
Muscle - Skeletal: p = 0.00968
Minor Salivary Gland: p = 0.02
M95Diagnoses - main ICD10: M95 Other acquired deformities of musculoskeletal system and connective tissueUK Biobank (UKBB)Neale Lab20181983609963Brain - Caudate (basal ganglia): p = 0.00158
Brain - Nucleus accumbens (basal ganglia): p = 0.00409
Brain - Putamen (basal ganglia): p = 0.0064
S09Diagnoses - main ICD10: S09 Other and unspecified injuries of headUK Biobank (UKBB)Neale Lab201813333598613Pituitary: p = 0.02
Colon - Transverse: p = 0.02
Breast - Mammary Tissue: p = 0.03
T82Diagnoses - main ICD10: T82 Complications of cardiac and vascular prosthetic devices, implants and graftsUK Biobank (UKBB)Neale Lab201811333600613Breast - Mammary Tissue: p = 4.22E-4
Artery - Aorta: p = 0.00864
Artery - Tibial: p = 0.01
J20Diagnoses - main ICD10: J20 Acute bronchitisUK Biobank (UKBB)Neale Lab20181023610923Esophagus - Mucosa: p = 0.00281
Minor Salivary Gland: p = 0.00707
Small Intestine - Terminal Ileum: p = 0.01
H26Diagnoses - main ICD10: H26 Other cataractUK Biobank (UKBB)Neale Lab2018113063498884Artery - Aorta: p = 0.00105
Colon - Sigmoid: p = 0.00574
Spleen: p = 0.00574
S42Diagnoses - main ICD10: S42 Fracture of shoulder and upper armUK Biobank (UKBB)Neale Lab201817913594033Vagina: p = 0.03
Skin - Sun Exposed (Lower leg): p = 0.04
Skin - Not Sun Exposed (Suprapubic): p = 0.09
H04Diagnoses - main ICD10: H04 Disorders of lachrymal systemUK Biobank (UKBB)Neale Lab201814763597183Uterus: p = 0.00332
Pituitary: p = 0.0051
Adrenal Gland: p = 0.03
K31Diagnoses - main ICD10: K31 Other diseases of stomach and duodenumUK Biobank (UKBB)Neale Lab201823743588202Small Intestine - Terminal Ileum: p = 5.19E-5
Brain - Putamen (basal ganglia): p = 0.003
Brain - Anterior cingulate cortex (BA24): p = 0.00471
E05Diagnoses - main ICD10: E05 Thyrotoxicosis [hyperthyroidism]UK Biobank (UKBB)Neale Lab20183923608025Lung: p = 1.51E-5
Spleen: p = 1.51E-5
Whole Blood: p = 1.88E-4
N93Diagnoses - main ICD10: N93 Other abnormal uterine and vaginal bleedingUK Biobank (UKBB)Neale Lab201824553587393Esophagus - Muscularis: p = 8.45E-5
Esophagus - Gastroesophageal Junction: p = 7.8E-4
Adipose - Visceral (Omentum): p = 0.0034
E21Diagnoses - main ICD10: E21 Hyperparathyroidism and other disorders of parathyroid glandUK Biobank (UKBB)Neale Lab20183083608863Muscle - Skeletal: p = 0.05
Minor Salivary Gland: p = 0.06
Small Intestine - Terminal Ileum: p = 0.07
I31Diagnoses - main ICD10: I31 Other diseases of pericardiumUK Biobank (UKBB)Neale Lab20183823608123Lung: p = 8.41E-4
Brain - Spinal cord (cervical c-1): p = 0.00363
Stomach: p = 0.02
Z45Diagnoses - main ICD10: Z45 Adjustment and management of implanted deviceUK Biobank (UKBB)Neale Lab201822093589853Thyroid: p = 0.00721
Heart - Atrial Appendage: p = 0.02
Small Intestine - Terminal Ileum: p = 0.03
R93Diagnoses - main ICD10: R93 Abnormal findings on diagnostic imaging of other body structuresUK Biobank (UKBB)Neale Lab201812173599773Small Intestine - Terminal Ileum: p = 0.00228
Liver: p = 0.02
Kidney - Cortex: p = 0.04
J34Diagnoses - main ICD10: J34 Other disorders of nose and nasal sinusesUK Biobank (UKBB)Neale Lab201844383567563Adrenal Gland: p = 2.37E-4
Esophagus - Gastroesophageal Junction: p = 3.12E-4
Esophagus - Muscularis: p = 8.8E-4
K38Diagnoses - main ICD10: K38 Other diseases of appendixUK Biobank (UKBB)Neale Lab20181023610923Adipose - Visceral (Omentum): p = 5.86E-4
Breast - Mammary Tissue: p = 0.00429
Nerve - Tibial: p = 0.01
K25Diagnoses - main ICD10: K25 Gastric ulcerUK Biobank (UKBB)Neale Lab201818343593603Uterus: p = 0.00874
Ovary: p = 0.02
Testis: p = 0.05
H90Diagnoses - main ICD10: H90 Conductive and sensorineural hearing lossUK Biobank (UKBB)Neale Lab20182823609122Whole Blood: p = 0.0025
Testis: p = 0.07
Brain - Amygdala: p = 0.08
K82Diagnoses - main ICD10: K82 Other diseases of gallbladderUK Biobank (UKBB)Neale Lab20182933609013Testis: p = 0.00678
Adipose - Visceral (Omentum): p = 0.02
Nerve - Tibial: p = 0.02
R39Diagnoses - main ICD10: R39 Other symptoms and signs involving the urinary systemUK Biobank (UKBB)Neale Lab201826983584963Artery - Tibial: p = 0.00228
Pancreas: p = 0.01
Artery - Coronary: p = 0.05
I72Diagnoses - main ICD10: I72 Other aneurysmUK Biobank (UKBB)Neale Lab20182193609753Uterus: p = 0.04
Thyroid: p = 0.09
Vagina: p = 0.11
I62Diagnoses - main ICD10: I62 Other nontraumatic intracranial haemorrhageUK Biobank (UKBB)Neale Lab20182363609583Esophagus - Gastroesophageal Junction: p = 0.02
Whole Blood: p = 0.02
Colon - Transverse: p = 0.03
C48Diagnoses - main ICD10: C48 Malignant neoplasm of retroperitoneum and peritoneumUK Biobank (UKBB)Neale Lab20181223610722Muscle - Skeletal: p = 0.00502
Liver: p = 0.05
Pituitary: p = 0.05
L73Diagnoses - main ICD10: L73 Other follicular disordersUK Biobank (UKBB)Neale Lab20182463609483Adipose - Visceral (Omentum): p = 8.61E-4
Brain - Spinal cord (cervical c-1): p = 0.00222
Adipose - Subcutaneous: p = 0.00534
R05Diagnoses - main ICD10: R05 CoughUK Biobank (UKBB)Neale Lab20189843602103Whole Blood: p = 0.00543
Esophagus - Muscularis: p = 0.01
Heart - Atrial Appendage: p = 0.04
N95Diagnoses - main ICD10: N95 Menopausal and other perimenopausal disordersUK Biobank (UKBB)Neale Lab201864963546983Artery - Aorta: p = 0.02
Artery - Coronary: p = 0.02
Colon - Sigmoid: p = 0.03
R59Diagnoses - main ICD10: R59 Enlarged lymph nodesUK Biobank (UKBB)Neale Lab201810113601833Esophagus - Mucosa: p = 5.16E-6
Skin - Sun Exposed (Lower leg): p = 0.00115
Vagina: p = 0.00288
T87Diagnoses - main ICD10: T87 Complications peculiar to reattachment and amputationUK Biobank (UKBB)Neale Lab20181083610863Muscle - Skeletal: p = 0.00968
Prostate: p = 0.02
Pituitary: p = 0.03
L91Diagnoses - main ICD10: L91 Hypertrophic disorders of skinUK Biobank (UKBB)Neale Lab20186153605793Artery - Tibial: p = 0.01
Artery - Aorta: p = 0.03
Brain - Spinal cord (cervical c-1): p = 0.03
S63Diagnoses - main ICD10: S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand levelUK Biobank (UKBB)Neale Lab20184113607833Brain - Frontal Cortex (BA9): p = 0.00707
Artery - Coronary: p = 0.01
Artery - Tibial: p = 0.02
C44Diagnoses - main ICD10: C44 Other malignant neoplasms of skinUK Biobank (UKBB)Neale Lab201890863521085Spleen: p = 0.00228
Testis: p = 0.00834
Esophagus - Mucosa: p = 0.00894
M50Diagnoses - main ICD10: M50 Cervical disk disordersUK Biobank (UKBB)Neale Lab20188753603192Prostate: p = 0.00121
Esophagus - Muscularis: p = 0.00315
Esophagus - Gastroesophageal Junction: p = 0.00495
N30Diagnoses - main ICD10: N30 CystitisUK Biobank (UKBB)Neale Lab201815753596192Prostate: p = 0.00352
Kidney - Cortex: p = 0.02
Liver: p = 0.02
I42Diagnoses - main ICD10: I42 CardiomyopathyUK Biobank (UKBB)Neale Lab20184793607153Muscle - Skeletal: p = 0.03
Liver: p = 0.06
Nerve - Tibial: p = 0.06
N10Diagnoses - main ICD10: N10 Acute tubulo-interstitial nephritisUK Biobank (UKBB)Neale Lab20181243610703Pituitary: p = 0.00259
Small Intestine - Terminal Ileum: p = 0.00624
Skin - Sun Exposed (Lower leg): p = 0.00952
N73Diagnoses - main ICD10: N73 Other female pelvic inflammatory diseasesUK Biobank (UKBB)Neale Lab20186213605733Pituitary: p = 0.00183
Thyroid: p = 0.00468
Esophagus - Mucosa: p = 0.02
Z35Diagnoses - main ICD10: Z35 Supervision of high-risk pregnancyUK Biobank (UKBB)Neale Lab20181263610683Prostate: p = 0.05
Brain - Caudate (basal ganglia): p = 0.10
Skin - Not Sun Exposed (Suprapubic): p = 0.10
R73Diagnoses - main ICD10: R73 Elevated blood glucose levelUK Biobank (UKBB)Neale Lab20181693610253Minor Salivary Gland: p = 0.00103
Colon - Transverse: p = 0.00172
Colon - Sigmoid: p = 0.04
E03Diagnoses - main ICD10: E03 Other hypothyroidismUK Biobank (UKBB)Neale Lab20181183610763Whole Blood: p = 0.03
Artery - Coronary: p = 0.04
Brain - Frontal Cortex (BA9): p = 0.06
T85Diagnoses - main ICD10: T85 Complications of other internal prosthetic devices, implants and graftsUK Biobank (UKBB)Neale Lab201815013596932Breast - Mammary Tissue: p = 0.02
Minor Salivary Gland: p = 0.03
Brain - Spinal cord (cervical c-1): p = 0.04
C81Diagnoses - main ICD10: C81 Hodgkin's diseaseUK Biobank (UKBB)Neale Lab20181503610443Lung: p = 1.06E-4
Spleen: p = 0.00414
Colon - Transverse: p = 0.00929
D64Diagnoses - main ICD10: D64 Other anaemiasUK Biobank (UKBB)Neale Lab201837023574925Lung: p = 9.08E-5
Spleen: p = 1.0E-4
Liver: p = 0.00122
M60Diagnoses - main ICD10: M60 MyositisUK Biobank (UKBB)Neale Lab20181083610862Kidney - Cortex: p = 0.0051
Small Intestine - Terminal Ileum: p = 0.01
Spleen: p = 0.02
K44Diagnoses - main ICD10: K44 Diaphragmatic herniaUK Biobank (UKBB)Neale Lab201880423531523Lung: p = 4.69E-5
Pancreas: p = 0.00183
Spleen: p = 0.0048
R06Diagnoses - main ICD10: R06 Abnormalities of breathingUK Biobank (UKBB)Neale Lab201841263570683Whole Blood: p = 0.00208
Pancreas: p = 0.02
Esophagus - Muscularis: p = 0.02
K01Diagnoses - main ICD10: K01 Embedded and impacted teethUK Biobank (UKBB)Neale Lab201814433597513Adipose - Subcutaneous: p = 0.00211
Esophagus - Gastroesophageal Junction: p = 0.01
Artery - Aorta: p = 0.02
G61Diagnoses - main ICD10: G61 Inflammatory polyneuropathyUK Biobank (UKBB)Neale Lab20182063609883Skin - Sun Exposed (Lower leg): p = 0.02
Spleen: p = 0.03
Artery - Aorta: p = 0.05
J03Diagnoses - main ICD10: J03 Acute tonsillitisUK Biobank (UKBB)Neale Lab20184053607893Minor Salivary Gland: p = 0.01
Artery - Aorta: p = 0.06
Colon - Transverse: p = 0.06
K42Diagnoses - main ICD10: K42 Umbilical herniaUK Biobank (UKBB)Neale Lab201825283586663Artery - Aorta: p = 0.04
Nerve - Tibial: p = 0.04
Brain - Cerebellum: p = 0.05
M80Diagnoses - main ICD10: M80 Osteoporosis with pathological fractureUK Biobank (UKBB)Neale Lab20181753610193Whole Blood: p = 4.34E-4
Heart - Left Ventricle: p = 0.02
Adipose - Visceral (Omentum): p = 0.03
N39Diagnoses - main ICD10: N39 Other disorders of urinary systemUK Biobank (UKBB)Neale Lab2018105513506434Esophagus - Gastroesophageal Junction: p = 3.33E-4
Esophagus - Muscularis: p = 0.00436
Nerve - Tibial: p = 0.00996
K56Diagnoses - main ICD10: K56 Paralytic ileus and intestinal obstruction without herniaUK Biobank (UKBB)Neale Lab201818513593433Adrenal Gland: p = 0.00411
Brain - Substantia nigra: p = 0.01
Liver: p = 0.01
C20Diagnoses - main ICD10: C20 Malignant neoplasm of rectumUK Biobank (UKBB)Neale Lab201811183600763Skin - Not Sun Exposed (Suprapubic): p = 0.00281
Skin - Sun Exposed (Lower leg): p = 0.0067
Colon - Transverse: p = 0.01
O13Diagnoses - main ICD10: O13 Gestational [pregnancy-induced] hypertension without significant proteinuriaUK Biobank (UKBB)Neale Lab20182623609323Nerve - Tibial: p = 9.63E-4
Ovary: p = 0.02
Pituitary: p = 0.02
I33Diagnoses - main ICD10: I33 Acute and subacute endocarditisUK Biobank (UKBB)Neale Lab20181333610613Ovary: p = 0.02
Esophagus - Gastroesophageal Junction: p = 0.03
Testis: p = 0.04
H80Diagnoses - main ICD10: H80 OtosclerosisUK Biobank (UKBB)Neale Lab20182213609734Esophagus - Gastroesophageal Junction: p = 4.42E-4
Liver: p = 0.00128
Colon - Sigmoid: p = 0.00414
Q38Diagnoses - main ICD10: Q38 Other congenital malformations of tongue, mouth and pharynxUK Biobank (UKBB)Neale Lab20181493610453Colon - Sigmoid: p = 0.00304
Stomach: p = 0.01
Esophagus - Muscularis: p = 0.02
R31Diagnoses - main ICD10: R31 Unspecified haematuriaUK Biobank (UKBB)Neale Lab2018112833499115Spleen: p = 1.4E-7
Lung: p = 4.78E-6
Whole Blood: p = 1.99E-4
O00Diagnoses - main ICD10: O00 Ectopic pregnancyUK Biobank (UKBB)Neale Lab20182443609503Muscle - Skeletal: p = 0.02
Testis: p = 0.02
Whole Blood: p = 0.04
M71Diagnoses - main ICD10: M71 Other bursopathiesUK Biobank (UKBB)Neale Lab20184283607662Esophagus - Muscularis: p = 0.04
Whole Blood: p = 0.07
Esophagus - Gastroesophageal Junction: p = 0.07
M15Diagnoses - main ICD10: M15 PolyarthrosisUK Biobank (UKBB)Neale Lab201812643599303Artery - Aorta: p = 2.79E-4
Artery - Tibial: p = 0.00183
Muscle - Skeletal: p = 0.00475
H69Diagnoses - main ICD10: H69 Other disorders of Eustachian tubeUK Biobank (UKBB)Neale Lab20181193610753Ovary: p = 0.0096
Skin - Sun Exposed (Lower leg): p = 0.0096
Skin - Not Sun Exposed (Suprapubic): p = 0.01
G20Diagnoses - main ICD10: G20 Parkinson's diseaseUK Biobank (UKBB)Neale Lab20182063609883Skin - Not Sun Exposed (Suprapubic): p = 0.00592
Skin - Sun Exposed (Lower leg): p = 0.00592
Kidney - Cortex: p = 0.03
I25Diagnoses - main ICD10: I25 Chronic ischaemic heart diseaseUK Biobank (UKBB)Neale Lab2018127693484255Artery - Coronary: p = 6.93E-6
Artery - Tibial: p = 2.83E-5
Colon - Sigmoid: p = 0.00112
D32Diagnoses - main ICD10: D32 Benign neoplasm of meningesUK Biobank (UKBB)Neale Lab20183273608673Lung: p = 0.02
Stomach: p = 0.04
Nerve - Tibial: p = 0.04
O02Diagnoses - main ICD10: O02 Other abnormal products of conceptionUK Biobank (UKBB)Neale Lab201811063600882Esophagus - Mucosa: p = 0.01
Skin - Not Sun Exposed (Suprapubic): p = 0.01
Adrenal Gland: p = 0.03
N80Diagnoses - main ICD10: N80 EndometriosisUK Biobank (UKBB)Neale Lab201814963596983Adrenal Gland: p = 2.44E-4
Lung: p = 0.00225
Pituitary: p = 0.00333
N50Diagnoses - main ICD10: N50 Other disorders of male genital organsUK Biobank (UKBB)Neale Lab201818293593653Small Intestine - Terminal Ileum: p = 0.00319
Colon - Transverse: p = 0.00321
Vagina: p = 0.00416
S05Diagnoses - main ICD10: S05 Injury of eye and orbitUK Biobank (UKBB)Neale Lab20181593610353Stomach: p = 0.02
Pancreas: p = 0.02
Spleen: p = 0.03
D21Diagnoses - main ICD10: D21 Other benign neoplasms of connective and other soft tissueUK Biobank (UKBB)Neale Lab20183793608153Spleen: p = 0.02
Heart - Atrial Appendage: p = 0.02
Whole Blood: p = 0.03
H66Diagnoses - main ICD10: H66 Suppurative and unspecified otitis mediaUK Biobank (UKBB)Neale Lab20184473607473Brain - Cerebellar Hemisphere: p = 0.02
Brain - Cerebellum: p = 0.02
Brain - Substantia nigra: p = 0.02
F05Diagnoses - main ICD10: F05 Delirium, not induced by alcohol and other psychoactive substancesUK Biobank (UKBB)Neale Lab20181063610882Artery - Coronary: p = 0.00259
Uterus: p = 0.01
Artery - Aorta: p = 0.01
K63Diagnoses - main ICD10: K63 Other diseases of intestineUK Biobank (UKBB)Neale Lab201880413531533Breast - Mammary Tissue: p = 0.00674
Pituitary: p = 0.01
Brain - Spinal cord (cervical c-1): p = 0.02
R12Diagnoses - main ICD10: R12 HeartburnUK Biobank (UKBB)Neale Lab20188913603033Spleen: p = 0.00192
Artery - Aorta: p = 0.02
Pancreas: p = 0.04
K76Diagnoses - main ICD10: K76 Other diseases of liverUK Biobank (UKBB)Neale Lab20185763606183Colon - Sigmoid: p = 1.57E-4
Esophagus - Gastroesophageal Junction: p = 0.00236
Kidney - Cortex: p = 0.00548
T50Diagnoses - main ICD10: T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substancesUK Biobank (UKBB)Neale Lab20182313609633Uterus: p = 0.00488
Lung: p = 0.00719
Whole Blood: p = 0.00719
D25Diagnoses - main ICD10: D25 Leiomyoma of uterusUK Biobank (UKBB)Neale Lab201855073556874Pancreas: p = 0.00312
Skin - Not Sun Exposed (Suprapubic): p = 0.01
Uterus: p = 0.01
D35Diagnoses - main ICD10: D35 Benign neoplasm of other and unspecified endocrine glandsUK Biobank (UKBB)Neale Lab20185703606242Breast - Mammary Tissue: p = 0.02
Adipose - Subcutaneous: p = 0.02
Kidney - Cortex: p = 0.07
D30Diagnoses - main ICD10: D30 Benign neoplasm of urinary organsUK Biobank (UKBB)Neale Lab20181153610792Uterus: p = 0.03
Brain - Cerebellum: p = 0.05
Muscle - Skeletal: p = 0.06
D23Diagnoses - main ICD10: D23 Other benign neoplasms of skinUK Biobank (UKBB)Neale Lab201830853581093Vagina: p = 0.0075
Kidney - Cortex: p = 0.03
Skin - Not Sun Exposed (Suprapubic): p = 0.03
R68Diagnoses - main ICD10: R68 Other general symptoms and signsUK Biobank (UKBB)Neale Lab20181053610893Colon - Sigmoid: p = 0.03
Lung: p = 0.04
Colon - Transverse: p = 0.05
J36Diagnoses - main ICD10: J36 Peritonsillar abscessUK Biobank (UKBB)Neale Lab20183383608563Nerve - Tibial: p = 0.03
Ovary: p = 0.03
Spleen: p = 0.04
E66Diagnoses - main ICD10: E66 ObesityUK Biobank (UKBB)Neale Lab20183533608413Liver: p = 0.01
Kidney - Cortex: p = 0.02
Pituitary: p = 0.03
N41Diagnoses - main ICD10: N41 Inflammatory diseases of prostateUK Biobank (UKBB)Neale Lab20188433603513Prostate: p = 0.00488
Stomach: p = 0.01
Ovary: p = 0.02
J93Diagnoses - main ICD10: J93 PneumothoraxUK Biobank (UKBB)Neale Lab20183083608862Esophagus - Muscularis: p = 0.00409
Artery - Aorta: p = 0.00981
Artery - Coronary: p = 0.00981
I61Diagnoses - main ICD10: I61 Intracerebral haemorrhageUK Biobank (UKBB)Neale Lab20184933607013Skin - Not Sun Exposed (Suprapubic): p = 9.99E-4
Skin - Sun Exposed (Lower leg): p = 0.00253
Adipose - Visceral (Omentum): p = 0.04
R54Diagnoses - main ICD10: R54 SenilityUK Biobank (UKBB)Neale Lab20181213610733Kidney - Cortex: p = 0.02
Lung: p = 0.02
Vagina: p = 0.05
H02Diagnoses - main ICD10: H02 Other disorders of eyelidUK Biobank (UKBB)Neale Lab201842943569003Brain - Caudate (basal ganglia): p = 0.02
Stomach: p = 0.02
Prostate: p = 0.05
C25Diagnoses - main ICD10: C25 Malignant neoplasm of pancreasUK Biobank (UKBB)Neale Lab20184033607913Liver: p = 0.02
Stomach: p = 0.02
Prostate: p = 0.02
M24Diagnoses - main ICD10: M24 Other specific joint derangementsUK Biobank (UKBB)Neale Lab201812683599263Whole Blood: p = 0.00974
Esophagus - Muscularis: p = 0.02
Uterus: p = 0.03
S31Diagnoses - main ICD10: S31 Open wound of abdomen, lower back and pelvisUK Biobank (UKBB)Neale Lab20181003610942Artery - Aorta: p = 0.02
Stomach: p = 0.04
Artery - Tibial: p = 0.04
K26Diagnoses - main ICD10: K26 Duodenal ulcerUK Biobank (UKBB)Neale Lab201812913599033Esophagus - Mucosa: p = 0.04
Testis: p = 0.04
Skin - Sun Exposed (Lower leg): p = 0.04
T88Diagnoses - main ICD10: T88 Other complications of surgical and medical care, not elsewhere classifiedUK Biobank (UKBB)Neale Lab20182043609903Colon - Sigmoid: p = 0.0053
Heart - Atrial Appendage: p = 0.02
Stomach: p = 0.03
F99Diagnoses - main ICD10: F99 Mental disorder, not otherwise specifiedUK Biobank (UKBB)Neale Lab20181183610763Skin - Not Sun Exposed (Suprapubic): p = 1.15E-10
Skin - Sun Exposed (Lower leg): p = 1.15E-10
Adrenal Gland: p = 0.05
D36Diagnoses - main ICD10: D36 Benign neoplasm of other and unspecified sitesUK Biobank (UKBB)Neale Lab20185043606903Prostate: p = 0.00175
Vagina: p = 0.00952
Lung: p = 0.01
J01Diagnoses - main ICD10: J01 Acute sinusitisUK Biobank (UKBB)Neale Lab20181123610823Pancreas: p = 0.00783
Brain - Caudate (basal ganglia): p = 0.09
Brain - Nucleus accumbens (basal ganglia): p = 0.09
G93Diagnoses - main ICD10: G93 Other disorders of brainUK Biobank (UKBB)Neale Lab20182933609013Kidney - Cortex: p = 1.69E-4
Testis: p = 0.00254
Brain - Cerebellar Hemisphere: p = 0.01
F10Diagnoses - main ICD10: F10 Mental and behavioural disorders due to use of alcoholUK Biobank (UKBB)Neale Lab20187863604083Esophagus - Muscularis: p = 0.06
Artery - Coronary: p = 0.06
Esophagus - Gastroesophageal Junction: p = 0.08
M19Diagnoses - main ICD10: M19 Other arthrosisUK Biobank (UKBB)Neale Lab201841653570293Breast - Mammary Tissue: p = 0.00594
Minor Salivary Gland: p = 0.00594
Esophagus - Gastroesophageal Junction: p = 0.02
O32Diagnoses - main ICD10: O32 Maternal care for known or suspected malpresentation of foetusUK Biobank (UKBB)Neale Lab20186703605243Skin - Not Sun Exposed (Suprapubic): p = 0.05
Skin - Sun Exposed (Lower leg): p = 0.05
Esophagus - Mucosa: p = 0.08
G50Diagnoses - main ICD10: G50 Disorders of trigeminal nerveUK Biobank (UKBB)Neale Lab20182123609823Muscle - Skeletal: p = 0.02
Prostate: p = 0.02
Brain - Amygdala: p = 0.04
R53Diagnoses - main ICD10: R53 Malaise and fatigueUK Biobank (UKBB)Neale Lab20188183603763Artery - Tibial: p = 0.03
Uterus: p = 0.03
Colon - Transverse: p = 0.03
C45Diagnoses - main ICD10: C45 MesotheliomaUK Biobank (UKBB)Neale Lab20181503610442Colon - Sigmoid: p = 0.00352
Stomach: p = 0.00352
Artery - Tibial: p = 0.00862
M93Diagnoses - main ICD10: M93 Other osteochondropathiesUK Biobank (UKBB)Neale Lab20181033610913Artery - Coronary: p = 0.02
Colon - Sigmoid: p = 0.02
Vagina: p = 0.04
C15Diagnoses - main ICD10: C15 Malignant neoplasm of oesophagusUK Biobank (UKBB)Neale Lab20185193606753Liver: p = 5.62E-4
Brain - Spinal cord (cervical c-1): p = 0.02
Pituitary: p = 0.06
K22Diagnoses - main ICD10: K22 Other diseases of oesophagusUK Biobank (UKBB)Neale Lab201854943557003Whole Blood: p = 0.01
Spleen: p = 0.02
Brain - Caudate (basal ganglia): p = 0.02
N85Diagnoses - main ICD10: N85 Other noninflammatory disorders of uterus, except cervixUK Biobank (UKBB)Neale Lab201814893597053Brain - Cerebellar Hemisphere: p = 0.00599
Small Intestine - Terminal Ileum: p = 0.01
Prostate: p = 0.02
M96Diagnoses - main ICD10: M96 Postprocedural musculoskeletal disorders, not elsewhere classifiedUK Biobank (UKBB)Neale Lab20182513609432Colon - Sigmoid: p = 0.00742
Adipose - Visceral (Omentum): p = 0.02
Artery - Aorta: p = 0.02
T18Diagnoses - main ICD10: T18 Foreign body in alimentary tractUK Biobank (UKBB)Neale Lab20183223608723Colon - Sigmoid: p = 0.00151
Whole Blood: p = 0.02
Esophagus - Gastroesophageal Junction: p = 0.03
H27Diagnoses - main ICD10: H27 Other disorders of lensUK Biobank (UKBB)Neale Lab20181283610662Adrenal Gland: p = 0.00523
Liver: p = 0.01
Spleen: p = 0.01
L05Diagnoses - main ICD10: L05 Pilonidal cystUK Biobank (UKBB)Neale Lab20183943608002Skin - Sun Exposed (Lower leg): p = 0.00502
Heart - Atrial Appendage: p = 0.01
Skin - Not Sun Exposed (Suprapubic): p = 0.01
D22Diagnoses - main ICD10: D22 Melanocytic naeviUK Biobank (UKBB)Neale Lab201835013576933Thyroid: p = 0.00971
Esophagus - Mucosa: p = 0.01
Pituitary: p = 0.02
J22Diagnoses - main ICD10: J22 Unspecified acute lower respiratory infectionUK Biobank (UKBB)Neale Lab201831403580543Skin - Not Sun Exposed (Suprapubic): p = 0.02
Skin - Sun Exposed (Lower leg): p = 0.02
Vagina: p = 0.02
G43Diagnoses - main ICD10: G43 MigraineUK Biobank (UKBB)Neale Lab201810723601222Esophagus - Gastroesophageal Junction: p = 1.71E-4
Esophagus - Muscularis: p = 0.00154
Brain - Anterior cingulate cortex (BA24): p = 0.00651
F20Diagnoses - main ICD10: F20 SchizophreniaUK Biobank (UKBB)Neale Lab20181983609963Brain - Cortex: p = 0.01
Uterus: p = 0.02
Brain - Hippocampus: p = 0.04
J40Diagnoses - main ICD10: J40 Bronchitis, not specified as acute or chronicUK Biobank (UKBB)Neale Lab20181543610403Skin - Sun Exposed (Lower leg): p = 9.0E-4
Whole Blood: p = 0.00218
Skin - Not Sun Exposed (Suprapubic): p = 0.005
M41Diagnoses - main ICD10: M41 ScoliosisUK Biobank (UKBB)Neale Lab20181823610123Testis: p = 0.02
Pituitary: p = 0.04
Minor Salivary Gland: p = 0.06
R04Diagnoses - main ICD10: R04 Haemorrhage from respiratory passagesUK Biobank (UKBB)Neale Lab201828363583584Whole Blood: p = 6.94E-4
Uterus: p = 0.00115
Brain - Cerebellum: p = 0.00292
M54Diagnoses - main ICD10: M54 DorsalgiaUK Biobank (UKBB)Neale Lab201883613528334Pituitary: p = 0.00533
Pancreas: p = 0.02
Brain - Nucleus accumbens (basal ganglia): p = 0.03
M47Diagnoses - main ICD10: M47 SpondylosisUK Biobank (UKBB)Neale Lab201820043591903Brain - Cerebellum: p = 0.02
Colon - Sigmoid: p = 0.03
Testis: p = 0.03
N76Diagnoses - main ICD10: N76 Other inflammation of vagina and vulvaUK Biobank (UKBB)Neale Lab20184633607313Liver: p = 3.76E-4
Artery - Aorta: p = 0.04
Minor Salivary Gland: p = 0.04
H52Diagnoses - main ICD10: H52 Disorders of refraction and accommodationUK Biobank (UKBB)Neale Lab20181863610083Vagina: p = 1.94E-5
Lung: p = 0.01
Minor Salivary Gland: p = 0.02
I34Diagnoses - main ICD10: I34 Nonrheumatic mitral valve disordersUK Biobank (UKBB)Neale Lab20185523606423Brain - Substantia nigra: p = 0.0011
Brain - Cortex: p = 0.00298
Brain - Spinal cord (cervical c-1): p = 0.00744
R90Diagnoses - main ICD10: R90 Abnormal findings on diagnostic imaging of central nervous systemUK Biobank (UKBB)Neale Lab20181273610673Skin - Sun Exposed (Lower leg): p = 0.00686
Brain - Substantia nigra: p = 0.01
Skin - Not Sun Exposed (Suprapubic): p = 0.01
I87Diagnoses - main ICD10: I87 Other disorders of veinsUK Biobank (UKBB)Neale Lab20181233610713Whole Blood: p = 0.00416
Stomach: p = 0.05
Pancreas: p = 0.08
C92Diagnoses - main ICD10: C92 Myeloid leukaemiaUK Biobank (UKBB)Neale Lab20183283608663Esophagus - Mucosa: p = 0.00846
Prostate: p = 0.01
Muscle - Skeletal: p = 0.02
D47Diagnoses - main ICD10: D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissueUK Biobank (UKBB)Neale Lab20182573609374Liver: p = 0.00294
Thyroid: p = 0.00385
Kidney - Cortex: p = 0.00671
H11Diagnoses - main ICD10: H11 Other disorders of conjunctivaUK Biobank (UKBB)Neale Lab20184283607663Heart - Atrial Appendage: p = 0.03
Pancreas: p = 0.03
Prostate: p = 0.04
N62Diagnoses - main ICD10: N62 Hypertrophy of breastUK Biobank (UKBB)Neale Lab20185493606453Brain - Nucleus accumbens (basal ganglia): p = 0.00825
Brain - Hypothalamus: p = 0.01
Brain - Cerebellum: p = 0.02
H00Diagnoses - main ICD10: H00 Hordeolum and chalazionUK Biobank (UKBB)Neale Lab201814673597274Lung: p = 3.43E-5
Whole Blood: p = 1.81E-4
Spleen: p = 0.00354
N45Diagnoses - main ICD10: N45 Orchitis and epididymitisUK Biobank (UKBB)Neale Lab20186053605893Muscle - Skeletal: p = 0.00102
Minor Salivary Gland: p = 0.00282
Nerve - Tibial: p = 0.01
I48Diagnoses - main ICD10: I48 Atrial fibrillation and flutterUK Biobank (UKBB)Neale Lab201863563548385Heart - Atrial Appendage: p = 4.99E-9
Heart - Left Ventricle: p = 7.98E-7
Muscle - Skeletal: p = 1.29E-6
N83Diagnoses - main ICD10: N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligamentUK Biobank (UKBB)Neale Lab201822153589793Artery - Coronary: p = 4.22E-4
Artery - Tibial: p = 0.00232
Artery - Aorta: p = 0.01
R61Diagnoses - main ICD10: R61 HyperhidrosisUK Biobank (UKBB)Neale Lab20181203610743Vagina: p = 0.00398
Brain - Hippocampus: p = 0.01
Brain - Hypothalamus: p = 0.01
J43Diagnoses - main ICD10: J43 EmphysemaUK Biobank (UKBB)Neale Lab20181293610653Stomach: p = 0.0036
Small Intestine - Terminal Ileum: p = 0.00839
Ovary: p = 0.02
C18Diagnoses - main ICD10: C18 Malignant neoplasm of colonUK Biobank (UKBB)Neale Lab201822263589683Pancreas: p = 1.51E-4
Colon - Transverse: p = 0.00449
Stomach: p = 0.00449
D86Diagnoses - main ICD10: D86 SarcoidosisUK Biobank (UKBB)Neale Lab20181703610243Testis: p = 0.00162
Brain - Caudate (basal ganglia): p = 0.02
Esophagus - Mucosa: p = 0.03
D75Diagnoses - main ICD10: D75 Other diseases of blood and blood-forming organsUK Biobank (UKBB)Neale Lab20182963608982Vagina: p = 0.04
Artery - Coronary: p = 0.06
Artery - Tibial: p = 0.08
J35Diagnoses - main ICD10: J35 Chronic diseases of tonsils and adenoidsUK Biobank (UKBB)Neale Lab20186943605002Whole Blood: p = 0.00709
Colon - Sigmoid: p = 0.02
Prostate: p = 0.02
L30Diagnoses - main ICD10: L30 Other dermatitisUK Biobank (UKBB)Neale Lab20183343608602Skin - Sun Exposed (Lower leg): p = 0.05
Muscle - Skeletal: p = 0.09
Kidney - Cortex: p = 0.09
K35Diagnoses - main ICD10: K35 Acute appendicitisUK Biobank (UKBB)Neale Lab201824043587903Prostate: p = 0.00562
Colon - Sigmoid: p = 0.02
Esophagus - Muscularis: p = 0.02
D03Diagnoses - main ICD10: D03 Melanoma in situUK Biobank (UKBB)Neale Lab20185773606173Esophagus - Gastroesophageal Junction: p = 0.0029
Nerve - Tibial: p = 0.02
Vagina: p = 0.02
R19Diagnoses - main ICD10: R19 Other symptoms and signs involving the digestive system and abdomenUK Biobank (UKBB)Neale Lab201887963523983Skin - Not Sun Exposed (Suprapubic): p = 0.00675
Whole Blood: p = 0.04
Esophagus - Mucosa: p = 0.05
L27Diagnoses - main ICD10: L27 Dermatitis due to substances taken internallyUK Biobank (UKBB)Neale Lab20181193610753Esophagus - Gastroesophageal Junction: p = 0.00696
Esophagus - Muscularis: p = 0.00696
Brain - Spinal cord (cervical c-1): p = 0.02
Z13Diagnoses - main ICD10: Z13 Special screening examination for other diseases and disordersUK Biobank (UKBB)Neale Lab201822363589583Stomach: p = 0.01
Lung: p = 0.03
Artery - Coronary: p = 0.03
S22Diagnoses - main ICD10: S22 Fracture of rib(s), sternum and thoracic spineUK Biobank (UKBB)Neale Lab20189473602473Esophagus - Mucosa: p = 0.00103
Vagina: p = 0.00103
Nerve - Tibial: p = 0.01
S67Diagnoses - main ICD10: S67 Crushing injury of wrist and handUK Biobank (UKBB)Neale Lab20181043610903Colon - Transverse: p = 4.41E-4
Small Intestine - Terminal Ileum: p = 0.00801
Esophagus - Mucosa: p = 0.02
C83Diagnoses - main ICD10: C83 Diffuse non-Hodgkin's lymphomaUK Biobank (UKBB)Neale Lab20185873606073Adipose - Visceral (Omentum): p = 0.02
Thyroid: p = 0.02
Kidney - Cortex: p = 0.03
T78Diagnoses - main ICD10: T78 Adverse effects, not elsewhere classifiedUK Biobank (UKBB)Neale Lab20186473605473Heart - Atrial Appendage: p = 0.00153
Brain - Anterior cingulate cortex (BA24): p = 0.01
Brain - Frontal Cortex (BA9): p = 0.01
I24Diagnoses - main ICD10: I24 Other acute ischaemic heart diseasesUK Biobank (UKBB)Neale Lab20184873607073Liver: p = 0.00936
Small Intestine - Terminal Ileum: p = 0.01
Adipose - Subcutaneous: p = 0.02
J39Diagnoses - main ICD10: J39 Other diseases of upper respiratory tractUK Biobank (UKBB)Neale Lab20183703608243Pituitary: p = 0.03
Ovary: p = 0.07
Brain - Cerebellar Hemisphere: p = 0.10
H40Diagnoses - main ICD10: H40 GlaucomaUK Biobank (UKBB)Neale Lab201817153594794Adipose - Visceral (Omentum): p = 0.00149
Artery - Aorta: p = 0.00553
Kidney - Cortex: p = 0.00716
J15Diagnoses - main ICD10: J15 Bacterial pneumonia, not elsewhere classifiedUK Biobank (UKBB)Neale Lab20182263609683Adipose - Subcutaneous: p = 0.01
Prostate: p = 0.01
Artery - Tibial: p = 0.06
S80Diagnoses - main ICD10: S80 Superficial injury of lower legUK Biobank (UKBB)Neale Lab20182313609633Adipose - Subcutaneous: p = 0.00874
Adipose - Visceral (Omentum): p = 0.03
Artery - Tibial: p = 0.03
S20Diagnoses - main ICD10: S20 Superficial injury of thoraxUK Biobank (UKBB)Neale Lab20181523610423Prostate: p = 4.22E-4
Esophagus - Mucosa: p = 0.02
Thyroid: p = 0.02
H81Diagnoses - main ICD10: H81 Disorders of vestibular functionUK Biobank (UKBB)Neale Lab20183413608532Liver: p = 0.00527
Muscle - Skeletal: p = 0.03
Ovary: p = 0.03
O82Diagnoses - main ICD10: O82 Single delivery by Caesarean sectionUK Biobank (UKBB)Neale Lab20183393608553Skin - Not Sun Exposed (Suprapubic): p = 9.02E-5
Skin - Sun Exposed (Lower leg): p = 0.00149
Small Intestine - Terminal Ileum: p = 0.02
S30Diagnoses - main ICD10: S30 Superficial injury of abdomen, lower back and pelvisUK Biobank (UKBB)Neale Lab20182463609483Brain - Amygdala: p = 0.02
Brain - Anterior cingulate cortex (BA24): p = 0.02
Brain - Caudate (basal ganglia): p = 0.02
D46Diagnoses - main ICD10: D46 Myelodysplastic syndromesUK Biobank (UKBB)Neale Lab20181553610392Whole Blood: p = 0.02
Uterus: p = 0.04
Adipose - Visceral (Omentum): p = 0.07
A63Diagnoses - main ICD10: A63 Other predominantly sexually transmitted diseases, not elsewhere classifiedUK Biobank (UKBB)Neale Lab20181013610934Whole Blood: p = 0.00532
Colon - Transverse: p = 0.01
Brain - Cerebellum: p = 0.06
O47Diagnoses - main ICD10: O47 False labourUK Biobank (UKBB)Neale Lab20188613603333Esophagus - Gastroesophageal Junction: p = 0.00134
Esophagus - Muscularis: p = 0.00134
Uterus: p = 0.00835
I49Diagnoses - main ICD10: I49 Other cardiac arrhythmiasUK Biobank (UKBB)Neale Lab20188033603913Breast - Mammary Tissue: p = 0.00957
Adipose - Subcutaneous: p = 0.01
Adipose - Visceral (Omentum): p = 0.02
D27Diagnoses - main ICD10: D27 Benign neoplasm of ovaryUK Biobank (UKBB)Neale Lab20189463602483Brain - Hypothalamus: p = 0.00281
Kidney - Cortex: p = 0.00438
Brain - Cerebellar Hemisphere: p = 0.02
A08Diagnoses - main ICD10: A08 Viral and other specified intestinal infectionsUK Biobank (UKBB)Neale Lab20184633607313Artery - Tibial: p = 0.0027
Brain - Spinal cord (cervical c-1): p = 0.00289
Skin - Not Sun Exposed (Suprapubic): p = 0.00449
S51Diagnoses - main ICD10: S51 Open wound of forearmUK Biobank (UKBB)Neale Lab20181933610012Brain - Amygdala: p = 0.03
Brain - Hippocampus: p = 0.03
Brain - Hypothalamus: p = 0.04
R20Diagnoses - main ICD10: R20 Disturbances of skin sensationUK Biobank (UKBB)Neale Lab20189463602482Brain - Frontal Cortex (BA9): p = 0.05
Brain - Anterior cingulate cortex (BA24): p = 0.07
Brain - Cortex: p = 0.10
K05Diagnoses - main ICD10: K05 Gingivitis and periodontal diseasesUK Biobank (UKBB)Neale Lab20184583607363Colon - Sigmoid: p = 0.03
Esophagus - Gastroesophageal Junction: p = 0.03
Testis: p = 0.03
K40Diagnoses - main ICD10: K40 Inguinal herniaUK Biobank (UKBB)Neale Lab2018131473480475Spleen: p = 3.48E-5
Whole Blood: p = 0.00653
Uterus: p = 0.00739
N12Diagnoses - main ICD10: N12 Tubulo-interstitial nephritis, not specified as acute or chronicUK Biobank (UKBB)Neale Lab20185833606112Brain - Spinal cord (cervical c-1): p = 0.00566
Ovary: p = 0.05
Brain - Substantia nigra: p = 0.09
J45Diagnoses - main ICD10: J45 AsthmaUK Biobank (UKBB)Neale Lab201816933595015Lung: p = 3.6E-6
Spleen: p = 2.8E-5
Whole Blood: p = 0.00385
R41Diagnoses - main ICD10: R41 Other symptoms and signs involving cognitive functions and awarenessUK Biobank (UKBB)Neale Lab20188763603182Muscle - Skeletal: p = 0.02
Artery - Aorta: p = 0.03
Artery - Coronary: p = 0.05
R42Diagnoses - main ICD10: R42 Dizziness and giddinessUK Biobank (UKBB)Neale Lab201816803595143Uterus: p = 0.00853
Nerve - Tibial: p = 0.03
Heart - Left Ventricle: p = 0.04
D14Diagnoses - main ICD10: D14 Benign neoplasm of middle ear and respiratory systemUK Biobank (UKBB)Neale Lab20182033609912Brain - Substantia nigra: p = 0.00626
Whole Blood: p = 0.02
Brain - Amygdala: p = 0.02
M62Diagnoses - main ICD10: M62 Other disorders of muscleUK Biobank (UKBB)Neale Lab20183433608512Stomach: p = 2.0E-5
Spleen: p = 6.73E-4
Pancreas: p = 0.00862
I80Diagnoses - main ICD10: I80 Phlebitis and thrombophlebitisUK Biobank (UKBB)Neale Lab201822893589055Liver: p = 2.42E-5
Kidney - Cortex: p = 0.00171
Stomach: p = 0.00262
D10Diagnoses - main ICD10: D10 Benign neoplasm of mouth and pharynxUK Biobank (UKBB)Neale Lab20183713608232Heart - Left Ventricle: p = 0.04
Adrenal Gland: p = 0.05
Brain - Cerebellar Hemisphere: p = 0.08
M22Diagnoses - main ICD10: M22 Disorders of patellaUK Biobank (UKBB)Neale Lab20184023607923Brain - Caudate (basal ganglia): p = 0.00108
Brain - Putamen (basal ganglia): p = 0.0018
Brain - Nucleus accumbens (basal ganglia): p = 0.00294
H33Diagnoses - main ICD10: H33 Retinal detachments and breaksUK Biobank (UKBB)Neale Lab201826713585234Artery - Aorta: p = 1.16E-5
Artery - Coronary: p = 2.86E-5
Brain - Hippocampus: p = 0.02
D43Diagnoses - main ICD10: D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous systemUK Biobank (UKBB)Neale Lab20181153610793Esophagus - Mucosa: p = 2.54E-4
Vagina: p = 7.27E-4
Lung: p = 0.00406
N86Diagnoses - main ICD10: N86 Erosion and ectropion of cervix uteriUK Biobank (UKBB)Neale Lab20183563608383Adrenal Gland: p = 0.00324
Brain - Cerebellar Hemisphere: p = 0.05
Brain - Spinal cord (cervical c-1): p = 0.05
O42Diagnoses - main ICD10: O42 Premature rupture of membranesUK Biobank (UKBB)Neale Lab20186573605373Prostate: p = 0.00673
Stomach: p = 0.02
Brain - Caudate (basal ganglia): p = 0.02
R50Diagnoses - main ICD10: R50 Fever of unknown originUK Biobank (UKBB)Neale Lab201811563600383Heart - Left Ventricle: p = 0.03
Brain - Hypothalamus: p = 0.04
Brain - Cerebellar Hemisphere: p = 0.05
C77Diagnoses - main ICD10: C77 Secondary and unspecified malignant neoplasm of lymph nodesUK Biobank (UKBB)Neale Lab20186583605363Muscle - Skeletal: p = 0.00843
Pituitary: p = 0.00929
Small Intestine - Terminal Ileum: p = 0.03
S56Diagnoses - main ICD10: S56 Injury of muscle and tendon at forearm levelUK Biobank (UKBB)Neale Lab20181553610393Artery - Tibial: p = 0.0063
Colon - Sigmoid: p = 0.0063
Esophagus - Gastroesophageal Junction: p = 0.0063
L43Diagnoses - main ICD10: L43 Lichen planusUK Biobank (UKBB)Neale Lab20183743608203Pituitary: p = 0.00193
Whole Blood: p = 0.00484
Uterus: p = 0.07
S92Diagnoses - main ICD10: S92 Fracture of foot, except ankleUK Biobank (UKBB)Neale Lab20186813605133Pancreas: p = 0.0075
Liver: p = 0.02
Adipose - Subcutaneous: p = 0.03
G47Diagnoses - main ICD10: G47 Sleep disordersUK Biobank (UKBB)Neale Lab201827233584713Kidney - Cortex: p = 7.88E-4
Adipose - Subcutaneous: p = 0.00153
Artery - Coronary: p = 0.00184
S32Diagnoses - main ICD10: S32 Fracture of lumbar spine and pelvisUK Biobank (UKBB)Neale Lab20188743603203Esophagus - Gastroesophageal Junction: p = 0.00174
Esophagus - Muscularis: p = 0.02
Pituitary: p = 0.02
R69Diagnoses - main ICD10: R69 Unknown and unspecified causes of morbidityUK Biobank (UKBB)Neale Lab201882803529143Ovary: p = 0.00592
Pituitary: p = 0.00592
Colon - Transverse: p = 0.02
S43Diagnoses - main ICD10: S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdleUK Biobank (UKBB)Neale Lab20183253608692Liver: p = 0.01
Muscle - Skeletal: p = 0.06
Vagina: p = 0.08
I21Diagnoses - main ICD10: I21 Acute myocardial infarctionUK Biobank (UKBB)Neale Lab201859483552465Adipose - Visceral (Omentum): p = 3.76E-4
Adipose - Subcutaneous: p = 6.83E-4
Kidney - Cortex: p = 7.31E-4
M13Diagnoses - main ICD10: M13 Other arthritisUK Biobank (UKBB)Neale Lab201811103600842Kidney - Cortex: p = 0.0082
Esophagus - Mucosa: p = 0.02
Artery - Coronary: p = 0.05
D17Diagnoses - main ICD10: D17 Benign lipomatous neoplasmUK Biobank (UKBB)Neale Lab201843143568803Esophagus - Gastroesophageal Junction: p = 0.00153
Small Intestine - Terminal Ileum: p = 0.00531
Stomach: p = 0.00547
J86Diagnoses - main ICD10: J86 PyothoraxUK Biobank (UKBB)Neale Lab20181613610333Stomach: p = 0.00537
Pancreas: p = 0.00815
Whole Blood: p = 0.01
I70Diagnoses - main ICD10: I70 AtherosclerosisUK Biobank (UKBB)Neale Lab20185663606283Kidney - Cortex: p = 0.00537
Esophagus - Mucosa: p = 0.02
Brain - Nucleus accumbens (basal ganglia): p = 0.03
S82Diagnoses - main ICD10: S82 Fracture of lower leg, including ankleUK Biobank (UKBB)Neale Lab201845573566373Whole Blood: p = 2.6E-4
Kidney - Cortex: p = 0.00218
Uterus: p = 0.01
O44Diagnoses - main ICD10: O44 Placenta praeviaUK Biobank (UKBB)Neale Lab20181323610622Adrenal Gland: p = 2.55E-4
Brain - Anterior cingulate cortex (BA24): p = 0.00603
Brain - Hypothalamus: p = 0.00603
Z08Diagnoses - main ICD10: Z08 Follow-up examination after treatment for malignant neoplasmUK Biobank (UKBB)Neale Lab201842143569803Adipose - Subcutaneous: p = 0.00162
Kidney - Cortex: p = 0.0071
Lung: p = 0.0071
C09Diagnoses - main ICD10: C09 Malignant neoplasm of tonsilUK Biobank (UKBB)Neale Lab20181623610323Esophagus - Gastroesophageal Junction: p = 0.00154
Lung: p = 0.00222
Vagina: p = 0.00411
H25Diagnoses - main ICD10: H25 Senile cataractUK Biobank (UKBB)Neale Lab201863323548624Thyroid: p = 0.04
Adipose - Subcutaneous: p = 0.04
Liver: p = 0.04
N21Diagnoses - main ICD10: N21 Calculus of lower urinary tractUK Biobank (UKBB)Neale Lab20184713607232Nerve - Tibial: p = 0.05
Brain - Substantia nigra: p = 0.07
Colon - Sigmoid: p = 0.07
S68Diagnoses - main ICD10: S68 Traumatic amputation of wrist and handUK Biobank (UKBB)Neale Lab20183573608373Skin - Not Sun Exposed (Suprapubic): p = 0.01
Skin - Sun Exposed (Lower leg): p = 0.03
Pituitary: p = 0.04
F32Diagnoses - main ICD10: F32 Depressive episodeUK Biobank (UKBB)Neale Lab20187763604183Brain - Anterior cingulate cortex (BA24): p = 3.52E-5
Brain - Frontal Cortex (BA9): p = 0.00173
Brain - Hypothalamus: p = 0.00173
Q21Diagnoses - main ICD10: Q21 Congenital malformations of cardiac septaUK Biobank (UKBB)Neale Lab20183133608813Breast - Mammary Tissue: p = 0.0081
Spleen: p = 0.0091
Adipose - Subcutaneous: p = 0.02
M79Diagnoses - main ICD10: M79 Other soft tissue disorders, not elsewhere classifiedUK Biobank (UKBB)Neale Lab201869463542483Adipose - Visceral (Omentum): p = 0.00775
Liver: p = 0.01
Colon - Transverse: p = 0.01
R55Diagnoses - main ICD10: R55 Syncope and collapseUK Biobank (UKBB)Neale Lab201851833560113Ovary: p = 0.0027
Pituitary: p = 0.00964
Adrenal Gland: p = 0.01
K13Diagnoses - main ICD10: K13 Other diseases of lip and oral mucosaUK Biobank (UKBB)Neale Lab201821573590373Brain - Caudate (basal ganglia): p = 0.02
Brain - Putamen (basal ganglia): p = 0.02
Brain - Amygdala: p = 0.02
C34Diagnoses - main ICD10: C34 Malignant neoplasm of bronchus and lungUK Biobank (UKBB)Neale Lab201814273597673Heart - Atrial Appendage: p = 0.00813
Brain - Amygdala: p = 0.02
Brain - Anterior cingulate cortex (BA24): p = 0.02
I86Diagnoses - main ICD10: I86 Varicose veins of other sitesUK Biobank (UKBB)Neale Lab20182223609723Esophagus - Gastroesophageal Junction: p = 0.00459
Esophagus - Muscularis: p = 0.00708
Kidney - Cortex: p = 0.01
O60Diagnoses - main ICD10: O60 Preterm deliveryUK Biobank (UKBB)Neale Lab20181773610172Small Intestine - Terminal Ileum: p = 0.00961
Adipose - Subcutaneous: p = 0.02
Thyroid: p = 0.07
I64Diagnoses - main ICD10: I64 Stroke, not specified as haemorrhage or infarctionUK Biobank (UKBB)Neale Lab20187423604522Colon - Sigmoid: p = 0.00733
Esophagus - Muscularis: p = 0.00733
Esophagus - Gastroesophageal Junction: p = 0.03
Z47Diagnoses - main ICD10: Z47 Other orthopaedic follow-up careUK Biobank (UKBB)Neale Lab201827743584203Artery - Coronary: p = 0.00255
Spleen: p = 0.0051
Adipose - Subcutaneous: p = 0.02
G12Diagnoses - main ICD10: G12 Spinal muscular atrophy and related syndromesUK Biobank (UKBB)Neale Lab20181203610743Artery - Coronary: p = 0.00545
Artery - Tibial: p = 0.00861
Brain - Cerebellar Hemisphere: p = 0.00862
K43Diagnoses - main ICD10: K43 Ventral herniaUK Biobank (UKBB)Neale Lab201822493589453Nerve - Tibial: p = 0.00824
Uterus: p = 0.02
Artery - Coronary: p = 0.02
I50Diagnoses - main ICD10: I50 Heart failureUK Biobank (UKBB)Neale Lab201810883601063Pancreas: p = 7.64E-4
Prostate: p = 0.00686
Muscle - Skeletal: p = 0.01
N40Diagnoses - main ICD10: N40 Hyperplasia of prostateUK Biobank (UKBB)Neale Lab201851093560855Lung: p = 4.72E-4
Spleen: p = 4.72E-4
Whole Blood: p = 4.72E-4
S64Diagnoses - main ICD10: S64 Injury of nerves at wrist and hand levelUK Biobank (UKBB)Neale Lab20183723608223Liver: p = 0.00761
Brain - Spinal cord (cervical c-1): p = 0.01
Brain - Cerebellum: p = 0.02
O20Diagnoses - main ICD10: O20 Haemorrhage in early pregnancyUK Biobank (UKBB)Neale Lab20187383604563Nerve - Tibial: p = 0.01
Testis: p = 0.02
Skin - Sun Exposed (Lower leg): p = 0.03
T39Diagnoses - main ICD10: T39 Poisoning by nonopioid analgesics, antipyretics and antirheumaticsUK Biobank (UKBB)Neale Lab201811613600333Muscle - Skeletal: p = 0.00398
Stomach: p = 0.00559
Nerve - Tibial: p = 0.02
K81Diagnoses - main ICD10: K81 CholecystitisUK Biobank (UKBB)Neale Lab201819303592643Kidney - Cortex: p = 0.0078
Liver: p = 0.00993
Whole Blood: p = 0.00993
K58Diagnoses - main ICD10: K58 Irritable bowel syndromeUK Biobank (UKBB)Neale Lab201811213600733Heart - Atrial Appendage: p = 0.02
Adipose - Subcutaneous: p = 0.06
Testis: p = 0.08
B02Diagnoses - main ICD10: B02 Zoster [herpes zoster]UK Biobank (UKBB)Neale Lab20181613610332Minor Salivary Gland: p = 0.00107
Stomach: p = 0.0027
Lung: p = 0.0027
M48Diagnoses - main ICD10: M48 Other spondylopathiesUK Biobank (UKBB)Neale Lab201818903593043Stomach: p = 2.16E-4
Artery - Aorta: p = 0.00843
Adipose - Visceral (Omentum): p = 0.02
E04Diagnoses - main ICD10: E04 Other non-toxic goitreUK Biobank (UKBB)Neale Lab201810523601423Lung: p = 0.01
Nerve - Tibial: p = 0.03
Thyroid: p = 0.03
D18Diagnoses - main ICD10: D18 Haemangioma and lymphangioma, any siteUK Biobank (UKBB)Neale Lab20189273602673Colon - Transverse: p = 0.03
Whole Blood: p = 0.03
Artery - Aorta: p = 0.05
C78Diagnoses - main ICD10: C78 Secondary malignant neoplasm of respiratory and digestive organsUK Biobank (UKBB)Neale Lab201813783598163Pancreas: p = 0.00279
Heart - Left Ventricle: p = 0.00609
Artery - Coronary: p = 0.00957
O23Diagnoses - main ICD10: O23 Infections of genito-urinary tract in pregnancyUK Biobank (UKBB)Neale Lab20181093610853Esophagus - Mucosa: p = 0.00142
Brain - Putamen (basal ganglia): p = 0.00374
Brain - Caudate (basal ganglia): p = 0.0059
H61Diagnoses - main ICD10: H61 Other disorders of external earUK Biobank (UKBB)Neale Lab20186073605873Lung: p = 0.00317
Adipose - Visceral (Omentum): p = 0.02
Nerve - Tibial: p = 0.04
M10Diagnoses - main ICD10: M10 GoutUK Biobank (UKBB)Neale Lab20183153608793Esophagus - Gastroesophageal Junction: p = 0.00377
Heart - Atrial Appendage: p = 0.00377
Colon - Sigmoid: p = 0.00592
N48Diagnoses - main ICD10: N48 Other disorders of penisUK Biobank (UKBB)Neale Lab201813173598773Lung: p = 0.00224
Esophagus - Mucosa: p = 0.02
Vagina: p = 0.02
Z39Diagnoses - main ICD10: Z39 Postpartum care and examinationUK Biobank (UKBB)Neale Lab20183073608873Esophagus - Mucosa: p = 0.01
Minor Salivary Gland: p = 0.01
Vagina: p = 0.01
M85Diagnoses - main ICD10: M85 Other disorders of bone density and structureUK Biobank (UKBB)Neale Lab20181213610733Liver: p = 5.69E-4
Brain - Cerebellar Hemisphere: p = 0.00155
Brain - Cerebellum: p = 0.00155
L53Diagnoses - main ICD10: L53 Other erythematous conditionsUK Biobank (UKBB)Neale Lab20181113610833Breast - Mammary Tissue: p = 0.00623
Prostate: p = 0.00917
Adipose - Visceral (Omentum): p = 0.01
I63Diagnoses - main ICD10: I63 Cerebral infarctionUK Biobank (UKBB)Neale Lab201823533588413Liver: p = 0.01
Brain - Cerebellum: p = 0.02
Brain - Spinal cord (cervical c-1): p = 0.02
R91Diagnoses - main ICD10: R91 Abnormal findings on diagnostic imaging of lungUK Biobank (UKBB)Neale Lab201811303600643Adrenal Gland: p = 8.51E-4
Colon - Transverse: p = 0.00719
Liver: p = 0.00719
L40Diagnoses - main ICD10: L40 PsoriasisUK Biobank (UKBB)Neale Lab20184743607205Lung: p = 7.14E-6
Whole Blood: p = 1.36E-4
Spleen: p = 5.22E-4
N82Diagnoses - main ICD10: N82 Fistulae involving female genital tractUK Biobank (UKBB)Neale Lab20181163610783Colon - Transverse: p = 0.00624
Liver: p = 0.00624
Pancreas: p = 0.00955
R33Diagnoses - main ICD10: R33 Retention of urineUK Biobank (UKBB)Neale Lab201823643588303Skin - Sun Exposed (Lower leg): p = 3.39E-5
Skin - Not Sun Exposed (Suprapubic): p = 1.86E-4
Muscle - Skeletal: p = 0.00228
L97Diagnoses - main ICD10: L97 Ulcer of lower limb, not elsewhere classifiedUK Biobank (UKBB)Neale Lab20182623609323Colon - Transverse: p = 0.00109
Spleen: p = 0.02
Pituitary: p = 0.02
Q82Diagnoses - main ICD10: Q82 Other congenital malformations of skinUK Biobank (UKBB)Neale Lab20181043610903Testis: p = 0.00874
Breast - Mammary Tissue: p = 0.02
Uterus: p = 0.02
N35Diagnoses - main ICD10: N35 Urethral strictureUK Biobank (UKBB)Neale Lab201820373591572Colon - Sigmoid: p = 1.94E-4
Esophagus - Gastroesophageal Junction: p = 0.00445
Esophagus - Muscularis: p = 0.00445
Z52Diagnoses - main ICD10: Z52 Donors of organs and tissuesUK Biobank (UKBB)Neale Lab20182773609173Prostate: p = 0.04
Spleen: p = 0.04
Vagina: p = 0.05
N31Diagnoses - main ICD10: N31 Neuromuscular dysfunction of bladder, not elsewhere classifiedUK Biobank (UKBB)Neale Lab201810143601802Minor Salivary Gland: p = 4.88E-4
Esophagus - Mucosa: p = 0.00761
Vagina: p = 0.00761
R76Diagnoses - main ICD10: R76 Other abnormal immunological findings in serumUK Biobank (UKBB)Neale Lab20181213610732Muscle - Skeletal: p = 0.01
Adipose - Subcutaneous: p = 0.01
Adrenal Gland: p = 0.03
O80Diagnoses - main ICD10: O80 Single spontaneous deliveryUK Biobank (UKBB)Neale Lab201816723595222Brain - Nucleus accumbens (basal ganglia): p = 0.00907
Ovary: p = 0.01
Brain - Caudate (basal ganglia): p = 0.04
K50Diagnoses - main ICD10: K50 Crohn's disease [regional enteritis]UK Biobank (UKBB)Neale Lab20189683602263Whole Blood: p = 1.14E-5
Lung: p = 0.00129
Skin - Not Sun Exposed (Suprapubic): p = 0.01
K66Diagnoses - main ICD10: K66 Other disorders of peritoneumUK Biobank (UKBB)Neale Lab20184053607893Adipose - Subcutaneous: p = 0.00696
Adipose - Visceral (Omentum): p = 0.04
Breast - Mammary Tissue: p = 0.04
E22Diagnoses - main ICD10: E22 Hyperfunction of pituitary glandUK Biobank (UKBB)Neale Lab20181133610813Brain - Caudate (basal ganglia): p = 0.02
Skin - Sun Exposed (Lower leg): p = 0.02
Nerve - Tibial: p = 0.03
N75Diagnoses - main ICD10: N75 Diseases of Bartholin's glandUK Biobank (UKBB)Neale Lab20185903606042Skin - Sun Exposed (Lower leg): p = 0.00225
Small Intestine - Terminal Ileum: p = 0.01
Skin - Not Sun Exposed (Suprapubic): p = 0.01
K65Diagnoses - main ICD10: K65 PeritonitisUK Biobank (UKBB)Neale Lab20182443609502Brain - Amygdala: p = 0.0096
Muscle - Skeletal: p = 0.01
Brain - Cortex: p = 0.03
H43Diagnoses - main ICD10: H43 Disorders of vitreous bodyUK Biobank (UKBB)Neale Lab20184483607463Liver: p = 0.04
Spleen: p = 0.05
Small Intestine - Terminal Ileum: p = 0.07
Q18Diagnoses - main ICD10: Q18 Other congenital malformations of face and neckUK Biobank (UKBB)Neale Lab20181023610923Breast - Mammary Tissue: p = 0.00499
Adipose - Visceral (Omentum): p = 0.02
Brain - Caudate (basal ganglia): p = 0.02
K91Diagnoses - main ICD10: K91 Postprocedural disorders of digestive system, not elsewhere classifiedUK Biobank (UKBB)Neale Lab20186943605003Skin - Not Sun Exposed (Suprapubic): p = 1.69E-4
Skin - Sun Exposed (Lower leg): p = 5.08E-4
Lung: p = 0.02
S01Diagnoses - main ICD10: S01 Open wound of headUK Biobank (UKBB)Neale Lab201816943595003Heart - Atrial Appendage: p = 2.85E-4
Liver: p = 0.00372
Heart - Left Ventricle: p = 0.00843
A41Diagnoses - main ICD10: A41 Other septicaemiaUK Biobank (UKBB)Neale Lab201810963600983Whole Blood: p = 4.85E-5
Colon - Sigmoid: p = 0.02
Breast - Mammary Tissue: p = 0.03
D34Diagnoses - main ICD10: D34 Benign neoplasm of thyroid glandUK Biobank (UKBB)Neale Lab20181963609983Breast - Mammary Tissue: p = 0.0081
Colon - Transverse: p = 0.02
Brain - Caudate (basal ganglia): p = 0.03
M46Diagnoses - main ICD10: M46 Other inflammatory spondylopathiesUK Biobank (UKBB)Neale Lab20182753609192Artery - Aorta: p = 6.47E-4
Pancreas: p = 0.00109
Artery - Coronary: p = 0.00466
H59Diagnoses - main ICD10: H59 Postprocedural disorders of eye and adnexa, not elsewhere classifiedUK Biobank (UKBB)Neale Lab20181273610673Whole Blood: p = 0.02
Testis: p = 0.02
Stomach: p = 0.04
I77Diagnoses - main ICD10: I77 Other disorders of arteries and arteriolesUK Biobank (UKBB)Neale Lab20186743605203Breast - Mammary Tissue: p = 9.19E-5
Liver: p = 4.04E-4
Adipose - Subcutaneous: p = 0.00527
K41Diagnoses - main ICD10: K41 Femoral herniaUK Biobank (UKBB)Neale Lab20184663607283Esophagus - Mucosa: p = 0.00156
Nerve - Tibial: p = 0.02
Pituitary: p = 0.02
J06Diagnoses - main ICD10: J06 Acute upper respiratory infections of multiple and unspecified sitesUK Biobank (UKBB)Neale Lab20183563608382Pancreas: p = 5.72E-4
Stomach: p = 0.00278
Adrenal Gland: p = 0.00717
N60Diagnoses - main ICD10: N60 Benign mammary dysplasiaUK Biobank (UKBB)Neale Lab201811573600373Minor Salivary Gland: p = 0.02
Adipose - Visceral (Omentum): p = 0.03
Adipose - Subcutaneous: p = 0.04
L02Diagnoses - main ICD10: L02 Cutaneous abscess, furuncle and carbuncleUK Biobank (UKBB)Neale Lab201816973594973Skin - Sun Exposed (Lower leg): p = 0.01
Muscle - Skeletal: p = 0.03
Pancreas: p = 0.04
E86Diagnoses - main ICD10: E86 Volume depletionUK Biobank (UKBB)Neale Lab20181903610042Brain - Cerebellar Hemisphere: p = 0.02
Brain - Cerebellum: p = 0.02
Kidney - Cortex: p = 0.03
H35Diagnoses - main ICD10: H35 Other retinal disordersUK Biobank (UKBB)Neale Lab201815513596433Muscle - Skeletal: p = 1.69E-4
Thyroid: p = 0.02
Artery - Aorta: p = 0.02
I67Diagnoses - main ICD10: I67 Other cerebrovascular diseasesUK Biobank (UKBB)Neale Lab20184043607903Artery - Aorta: p = 0.01
Liver: p = 0.01
Thyroid: p = 0.01
L81Diagnoses - main ICD10: L81 Other disorders of pigmentationUK Biobank (UKBB)Neale Lab20185113606833Nerve - Tibial: p = 0.01
Vagina: p = 0.01
Small Intestine - Terminal Ileum: p = 0.02
G58Diagnoses - main ICD10: G58 Other mononeuropathiesUK Biobank (UKBB)Neale Lab20181323610623Esophagus - Mucosa: p = 0.00443
Vagina: p = 0.01
Skin - Not Sun Exposed (Suprapubic): p = 0.01
J18Diagnoses - main ICD10: J18 Pneumonia, organism unspecifiedUK Biobank (UKBB)Neale Lab201846303565643Lung: p = 0.00126
Small Intestine - Terminal Ileum: p = 0.01
Spleen: p = 0.01
S12Diagnoses - main ICD10: S12 Fracture of neckUK Biobank (UKBB)Neale Lab20182093609853Brain - Substantia nigra: p = 0.00414
Brain - Spinal cord (cervical c-1): p = 0.02
Brain - Cerebellar Hemisphere: p = 0.02
L90Diagnoses - main ICD10: L90 Atrophic disorders of skinUK Biobank (UKBB)Neale Lab201816833595113Adrenal Gland: p = 0.00696
Uterus: p = 0.03
Adipose - Visceral (Omentum): p = 0.04
K29Diagnoses - main ICD10: K29 Gastritis and duodenitisUK Biobank (UKBB)Neale Lab2018126783485163Pituitary: p = 0.00174
Vagina: p = 0.0022
Spleen: p = 0.03
K14Diagnoses - main ICD10: K14 Diseases of tongueUK Biobank (UKBB)Neale Lab20188433603513Breast - Mammary Tissue: p = 0.00191
Brain - Caudate (basal ganglia): p = 0.00308
Brain - Hypothalamus: p = 0.00308
R23Diagnoses - main ICD10: R23 Other skin changesUK Biobank (UKBB)Neale Lab20181433610513Brain - Spinal cord (cervical c-1): p = 0.00639
Breast - Mammary Tissue: p = 0.02
Liver: p = 0.02
C56Diagnoses - main ICD10: C56 Malignant neoplasm of ovaryUK Biobank (UKBB)Neale Lab20186933605013Breast - Mammary Tissue: p = 0.02
Nerve - Tibial: p = 0.04
Lung: p = 0.05
C19Diagnoses - main ICD10: C19 Malignant neoplasm of rectosigmoid junctionUK Biobank (UKBB)Neale Lab20184983606962Muscle - Skeletal: p = 0.01
Skin - Not Sun Exposed (Suprapubic): p = 0.02
Skin - Sun Exposed (Lower leg): p = 0.02
K30Diagnoses - main ICD10: K30 DyspepsiaUK Biobank (UKBB)Neale Lab201875863536083Adrenal Gland: p = 0.00761
Brain - Anterior cingulate cortex (BA24): p = 0.04
Brain - Cortex: p = 0.04
D70Diagnoses - main ICD10: D70 AgranulocytosisUK Biobank (UKBB)Neale Lab20189823602123Brain - Frontal Cortex (BA9): p = 8.53E-4
Brain - Hippocampus: p = 0.00226
Whole Blood: p = 0.00431
E87Diagnoses - main ICD10: E87 Other disorders of fluid, electrolyte and acid-base balanceUK Biobank (UKBB)Neale Lab20185643606303Brain - Nucleus accumbens (basal ganglia): p = 0.00678
Liver: p = 0.01
Brain - Putamen (basal ganglia): p = 0.02
O04Diagnoses - main ICD10: O04 Medical abortionUK Biobank (UKBB)Neale Lab20189233602712Heart - Left Ventricle: p = 0.00475
Colon - Sigmoid: p = 0.02
Heart - Atrial Appendage: p = 0.02
M00Diagnoses - main ICD10: M00 Pyogenic arthritisUK Biobank (UKBB)Neale Lab20182563609383Spleen: p = 1.23E-6
Whole Blood: p = 1.24E-4
Pituitary: p = 0.01
D45Diagnoses - main ICD10: D45 Polycythaemia veraUK Biobank (UKBB)Neale Lab20182493609453Artery - Aorta: p = 0.01
Artery - Coronary: p = 0.01
Colon - Transverse: p = 0.01
K12Diagnoses - main ICD10: K12 Stomatitis and related lesionsUK Biobank (UKBB)Neale Lab20182713609233Artery - Aorta: p = 1.35E-5
Artery - Coronary: p = 1.24E-4
Uterus: p = 1.24E-4
S91Diagnoses - main ICD10: S91 Open wound of ankle and footUK Biobank (UKBB)Neale Lab20181463610483Uterus: p = 1.84E-5
Artery - Aorta: p = 8.51E-4
Artery - Coronary: p = 8.51E-4
R18Diagnoses - main ICD10: R18 AscitesUK Biobank (UKBB)Neale Lab20183593608353Artery - Aorta: p = 3.43E-6
Artery - Coronary: p = 3.43E-6
Uterus: p = 5.18E-5
L98Diagnoses - main ICD10: L98 Other disorders of skin and subcutaneous tissue, not elsewhere classifiedUK Biobank (UKBB)Neale Lab201840353571593Colon - Sigmoid: p = 0.00224
Heart - Left Ventricle: p = 0.00308
Pancreas: p = 0.02
G24Diagnoses - main ICD10: G24 DystoniaUK Biobank (UKBB)Neale Lab20181073610873Colon - Transverse: p = 0.01
Spleen: p = 0.02
Esophagus - Gastroesophageal Junction: p = 0.09
J44Diagnoses - main ICD10: J44 Other chronic obstructive pulmonary diseaseUK Biobank (UKBB)Neale Lab201815313596634Whole Blood: p = 7.97E-5
Spleen: p = 0.00141
Vagina: p = 0.00763
Z42Diagnoses - main ICD10: Z42 Follow-up care involving plastic surgeryUK Biobank (UKBB)Neale Lab201819633592313Kidney - Cortex: p = 0.02
Adrenal Gland: p = 0.04
Breast - Mammary Tissue: p = 0.05
O68Diagnoses - main ICD10: O68 Labour and delivery complicated by foetal stress [distress]UK Biobank (UKBB)Neale Lab201818823593123Adipose - Visceral (Omentum): p = 0.00387
Small Intestine - Terminal Ileum: p = 0.00591
Stomach: p = 0.03
R13Diagnoses - main ICD10: R13 DysphagiaUK Biobank (UKBB)Neale Lab201834713577233Liver: p = 0.00218
Nerve - Tibial: p = 0.00218
Small Intestine - Terminal Ileum: p = 0.02
D63Diagnoses - main ICD10: D63 Anaemia in chronic diseases classified elsewhereUK Biobank (UKBB)Neale Lab20181143610803Prostate: p = 0.00843
Breast - Mammary Tissue: p = 0.02
Adipose - Subcutaneous: p = 0.03
I44Diagnoses - main ICD10: I44 Atrioventricular and left bundle-branch blockUK Biobank (UKBB)Neale Lab20186513605433Stomach: p = 0.02
Colon - Transverse: p = 0.03
Skin - Sun Exposed (Lower leg): p = 0.04
I71Diagnoses - main ICD10: I71 Aortic aneurysm and dissectionUK Biobank (UKBB)Neale Lab20185643606303Colon - Transverse: p = 0.00117
Small Intestine - Terminal Ileum: p = 0.00288
Artery - Coronary: p = 0.00703
N94Diagnoses - main ICD10: N94 Pain and other conditions associated with female genital organs and menstrual cycleUK Biobank (UKBB)Neale Lab201812953598993Liver: p = 0.00164
Adrenal Gland: p = 0.00901
Prostate: p = 0.04
I45Diagnoses - main ICD10: I45 Other conduction disordersUK Biobank (UKBB)Neale Lab20182923609022Adipose - Visceral (Omentum): p = 0.00721
Heart - Atrial Appendage: p = 0.01
Adipose - Subcutaneous: p = 0.02
Z71Diagnoses - main ICD10: Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classifiedUK Biobank (UKBB)Neale Lab20182183609763Prostate: p = 0.00696
Nerve - Tibial: p = 0.03
Colon - Sigmoid: p = 0.04
N92Diagnoses - main ICD10: N92 Excessive, frequent and irregular menstruationUK Biobank (UKBB)Neale Lab201884753527193Nerve - Tibial: p = 0.01
Ovary: p = 0.01
Prostate: p = 0.02
I12Diagnoses - main ICD10: I12 Hypertensive renal diseaseUK Biobank (UKBB)Neale Lab20181763610183Kidney - Cortex: p = 1.69E-4
Colon - Sigmoid: p = 0.01
Colon - Transverse: p = 0.01
N36Diagnoses - main ICD10: N36 Other disorders of urethraUK Biobank (UKBB)Neale Lab20183723608223Vagina: p = 0.00342
Nerve - Tibial: p = 0.04
Esophagus - Mucosa: p = 0.04
N99Diagnoses - main ICD10: N99 Postprocedural disorders of genito-urinary system, not elsewhere classifiedUK Biobank (UKBB)Neale Lab20186013605933Pituitary: p = 0.00993
Artery - Aorta: p = 0.02
Vagina: p = 0.03
L85Diagnoses - main ICD10: L85 Other epidermal thickeningUK Biobank (UKBB)Neale Lab20184163607783Brain - Cerebellar Hemisphere: p = 0.03
Adipose - Visceral (Omentum): p = 0.05
Spleen: p = 0.05
J90Diagnoses - main ICD10: J90 Pleural effusion, not elsewhere classifiedUK Biobank (UKBB)Neale Lab201810333601613Spleen: p = 0.00443
Lung: p = 0.00843
Ovary: p = 0.02
O69Diagnoses - main ICD10: O69 Labour and delivery complicated by umbilical cord complicationsUK Biobank (UKBB)Neale Lab20181683610263Spleen: p = 3.02E-6
Whole Blood: p = 0.00374
Thyroid: p = 0.01
M81Diagnoses - main ICD10: M81 Osteoporosis without pathological fractureUK Biobank (UKBB)Neale Lab20187373604573Heart - Left Ventricle: p = 0.00516
Esophagus - Gastroesophageal Junction: p = 0.02
Lung: p = 0.02
O14Diagnoses - main ICD10: O14 Gestational [pregnancy-induced] hypertension with significant proteinuriaUK Biobank (UKBB)Neale Lab20181843610102Pancreas: p = 0.00358
Stomach: p = 0.02
Brain - Frontal Cortex (BA9): p = 0.05
H34Diagnoses - main ICD10: H34 Retinal vascular occlusionsUK Biobank (UKBB)Neale Lab20183033608912Brain - Cortex: p = 0.00145
Brain - Anterior cingulate cortex (BA24): p = 0.00917
Brain - Frontal Cortex (BA9): p = 0.00917
H72Diagnoses - main ICD10: H72 Perforation of tympanic membraneUK Biobank (UKBB)Neale Lab20186423605523Esophagus - Muscularis: p = 5.46E-4
Esophagus - Gastroesophageal Junction: p = 9.23E-4
Adrenal Gland: p = 0.02
R94Diagnoses - main ICD10: R94 Abnormal results of function studiesUK Biobank (UKBB)Neale Lab20187363604583Ovary: p = 0.01
Breast - Mammary Tissue: p = 0.02
Brain - Cortex: p = 0.03
Z43Diagnoses - main ICD10: Z43 Attention to artificial openingsUK Biobank (UKBB)Neale Lab201813563598382Thyroid: p = 0.06
Spleen: p = 0.07
Liver: p = 0.09
M23Diagnoses - main ICD10: M23 Internal derangement of kneeUK Biobank (UKBB)Neale Lab2018118313493634Skin - Not Sun Exposed (Suprapubic): p = 0.00323
Skin - Sun Exposed (Lower leg): p = 0.00323
Adrenal Gland: p = 0.00508
O16Diagnoses - main ICD10: O16 Unspecified maternal hypertensionUK Biobank (UKBB)Neale Lab20183643608303Esophagus - Muscularis: p = 0.02
Artery - Aorta: p = 0.06
Esophagus - Gastroesophageal Junction: p = 0.07
C32Diagnoses - main ICD10: C32 Malignant neoplasm of larynxUK Biobank (UKBB)Neale Lab20181593610353Heart - Left Ventricle: p = 0.02
Prostate: p = 0.02
Brain - Hypothalamus: p = 0.04
I85Diagnoses - main ICD10: I85 Oesophageal varicesUK Biobank (UKBB)Neale Lab20182813609133Skin - Not Sun Exposed (Suprapubic): p = 0.00199
Heart - Left Ventricle: p = 0.06
Esophagus - Mucosa: p = 0.07
Z41Diagnoses - main ICD10: Z41 Procedures for purposes other than remedying health stateUK Biobank (UKBB)Neale Lab20186003605943Pancreas: p = 0.00933
Heart - Left Ventricle: p = 0.11
Muscle - Skeletal: p = 0.11
R79Diagnoses - main ICD10: R79 Other abnormal findings of blood chemistryUK Biobank (UKBB)Neale Lab201826223585724Skin - Sun Exposed (Lower leg): p = 5.15E-4
Skin - Not Sun Exposed (Suprapubic): p = 0.00122
Prostate: p = 0.00287
K11Diagnoses - main ICD10: K11 Diseases of salivary glandsUK Biobank (UKBB)Neale Lab20187583604363Adipose - Visceral (Omentum): p = 0.00103
Adipose - Subcutaneous: p = 0.00472
Pituitary: p = 0.00637
D11Diagnoses - main ICD10: D11 Benign neoplasm of major salivary glandsUK Biobank (UKBB)Neale Lab20183763608183Whole Blood: p = 0.03
Brain - Cerebellar Hemisphere: p = 0.07
Heart - Atrial Appendage: p = 0.07
T86Diagnoses - main ICD10: T86 Failure and rejection of transplanted organs and tissuesUK Biobank (UKBB)Neale Lab20181633610313Prostate: p = 0.02
Nerve - Tibial: p = 0.07
Whole Blood: p = 0.07
M16Diagnoses - main ICD10: M16 Coxarthrosis [arthrosis of hip]UK Biobank (UKBB)Neale Lab201891363520585Colon - Sigmoid: p = 2.24E-4
Spleen: p = 2.24E-4
Artery - Coronary: p = 7.13E-4
N49Diagnoses - main ICD10: N49 Inflammatory disorders of male genital organs, not elsewhere classifiedUK Biobank (UKBB)Neale Lab20181213610733Testis: p = 0.00308
Whole Blood: p = 0.02
Colon - Transverse: p = 0.06
C91Diagnoses - main ICD10: C91 Lymphoid leukaemiaUK Biobank (UKBB)Neale Lab20183493608453Skin - Sun Exposed (Lower leg): p = 0.01
Adipose - Subcutaneous: p = 0.02
Thyroid: p = 0.02
S83Diagnoses - main ICD10: S83 Dislocation, sprain and strain of joints and ligaments of kneeUK Biobank (UKBB)Neale Lab20185803606142Whole Blood: p = 0.00678
Small Intestine - Terminal Ileum: p = 0.02
Lung: p = 0.03
C54Diagnoses - main ICD10: C54 Malignant neoplasm of corpus uteriUK Biobank (UKBB)Neale Lab20189883602063Whole Blood: p = 9.78E-4
Muscle - Skeletal: p = 0.03
Artery - Tibial: p = 0.04
O48Diagnoses - main ICD10: O48 Prolonged pregnancyUK Biobank (UKBB)Neale Lab20184593607352Lung: p = 0.03
Colon - Sigmoid: p = 0.03
Colon - Transverse: p = 0.04
O21Diagnoses - main ICD10: O21 Excessive vomiting in pregnancyUK Biobank (UKBB)Neale Lab20181653610293Spleen: p = 0.00438
Lung: p = 0.02
Pituitary: p = 0.02
H49Diagnoses - main ICD10: H49 Paralytic strabismusUK Biobank (UKBB)Neale Lab20181353610593Uterus: p = 1.65E-4
Spleen: p = 5.93E-4
Kidney - Cortex: p = 0.00119
H50Diagnoses - main ICD10: H50 Other strabismusUK Biobank (UKBB)Neale Lab20186413605533Brain - Spinal cord (cervical c-1): p = 0.00288
Colon - Sigmoid: p = 0.00288
Adipose - Visceral (Omentum): p = 0.00678
C71Diagnoses - main ICD10: C71 Malignant neoplasm of brainUK Biobank (UKBB)Neale Lab20183683608263Ovary: p = 0.00803
Brain - Hippocampus: p = 0.01
Liver: p = 0.02
R40Diagnoses - main ICD10: R40 Somnolence, stupor and comaUK Biobank (UKBB)Neale Lab20181373610573Vagina: p = 0.00304
Heart - Atrial Appendage: p = 0.00377
Spleen: p = 0.00491
S00Diagnoses - main ICD10: S00 Superficial injury of headUK Biobank (UKBB)Neale Lab20189043602902Skin - Not Sun Exposed (Suprapubic): p = 0.00462
Skin - Sun Exposed (Lower leg): p = 0.00462
Breast - Mammary Tissue: p = 0.00825
O03Diagnoses - main ICD10: O03 Spontaneous abortionUK Biobank (UKBB)Neale Lab201811503600442Pancreas: p = 0.00434
Pituitary: p = 0.00527
Nerve - Tibial: p = 0.05
D04Diagnoses - main ICD10: D04 Carcinoma in situ of skinUK Biobank (UKBB)Neale Lab20184023607923Vagina: p = 0.00671
Muscle - Skeletal: p = 0.09
Spleen: p = 0.09
I47Diagnoses - main ICD10: I47 Paroxysmal tachycardiaUK Biobank (UKBB)Neale Lab201816853595093Small Intestine - Terminal Ileum: p = 0.01
Heart - Left Ventricle: p = 0.01
Lung: p = 0.01
Z48Diagnoses - main ICD10: Z48 Other surgical follow-up careUK Biobank (UKBB)Neale Lab20187873604072Adipose - Visceral (Omentum): p = 0.00111
Brain - Caudate (basal ganglia): p = 0.01
Brain - Frontal Cortex (BA9): p = 0.01
N32Diagnoses - main ICD10: N32 Other disorders of bladderUK Biobank (UKBB)Neale Lab201842383569563Muscle - Skeletal: p = 0.00843
Esophagus - Mucosa: p = 0.04
Minor Salivary Gland: p = 0.04
K55Diagnoses - main ICD10: K55 Vascular disorders of intestineUK Biobank (UKBB)Neale Lab20183623608322Brain - Cortex: p = 0.00168
Brain - Caudate (basal ganglia): p = 0.00445
Brain - Hippocampus: p = 0.00445
N70Diagnoses - main ICD10: N70 Salpingitis and oophoritisUK Biobank (UKBB)Neale Lab20181913610032Prostate: p = 0.00721
Vagina: p = 0.00866
Brain - Frontal Cortex (BA9): p = 0.07
R00Diagnoses - main ICD10: R00 Abnormalities of heart beatUK Biobank (UKBB)Neale Lab201825423586523Vagina: p = 0.00259
Skin - Sun Exposed (Lower leg): p = 0.00707
Artery - Aorta: p = 0.01
S62Diagnoses - main ICD10: S62 Fracture at wrist and hand levelUK Biobank (UKBB)Neale Lab201817633594313Brain - Substantia nigra: p = 0.00881
Brain - Cerebellar Hemisphere: p = 0.02
Pancreas: p = 0.02
K83Diagnoses - main ICD10: K83 Other diseases of biliary tractUK Biobank (UKBB)Neale Lab20188823603123Artery - Aorta: p = 0.01
Lung: p = 0.02
Adipose - Subcutaneous: p = 0.02
M51Diagnoses - main ICD10: M51 Other intervertebral disk disordersUK Biobank (UKBB)Neale Lab201846903565044Brain - Cerebellum: p = 0.00225
Brain - Caudate (basal ganglia): p = 0.00458
Brain - Cerebellar Hemisphere: p = 0.00458
N18Diagnoses - main ICD10: N18 Chronic renal failureUK Biobank (UKBB)Neale Lab20185213606732Brain - Substantia nigra: p = 0.01
Vagina: p = 0.03
Brain - Nucleus accumbens (basal ganglia): p = 0.03
O64Diagnoses - main ICD10: O64 Obstructed labour due to malposition and malpresentation of foetusUK Biobank (UKBB)Neale Lab20182343609603Artery - Aorta: p = 0.00199
Artery - Coronary: p = 0.00593
Stomach: p = 0.01
K62Diagnoses - main ICD10: K62 Other diseases of anus and rectumUK Biobank (UKBB)Neale Lab2018138823473123Esophagus - Gastroesophageal Junction: p = 0.01
Esophagus - Muscularis: p = 0.03
Colon - Sigmoid: p = 0.05
E27Diagnoses - main ICD10: E27 Other disorders of adrenal glandUK Biobank (UKBB)Neale Lab20181933610013Skin - Sun Exposed (Lower leg): p = 0.04
Thyroid: p = 0.04
Heart - Atrial Appendage: p = 0.05
Z29Diagnoses - main ICD10: Z29 Need for other prophylactic measuresUK Biobank (UKBB)Neale Lab20181063610883Skin - Sun Exposed (Lower leg): p = 0.00438
Skin - Not Sun Exposed (Suprapubic): p = 0.05
Brain - Cerebellar Hemisphere: p = 0.06
D26Diagnoses - main ICD10: D26 Other benign neoplasms of uterusUK Biobank (UKBB)Neale Lab20181643610302Colon - Transverse: p = 0.02
Liver: p = 0.05
Heart - Atrial Appendage: p = 0.07
D09Diagnoses - main ICD10: D09 Carcinoma in situ of other and unspecified sitesUK Biobank (UKBB)Neale Lab20181413610533Liver: p = 0.00308
Prostate: p = 0.009
Brain - Putamen (basal ganglia): p = 0.02
G45Diagnoses - main ICD10: G45 Transient cerebral ischaemic attacks and related syndromesUK Biobank (UKBB)Neale Lab201817443594503Liver: p = 0.00761
Adipose - Visceral (Omentum): p = 0.01
Skin - Not Sun Exposed (Suprapubic): p = 0.01
K11_VOLVUVolvulusUK Biobank (UKBB)Neale Lab20182203609743Brain - Cerebellar Hemisphere: p = 3.81E-5
Brain - Cerebellum: p = 0.00111
Brain - Cortex: p = 0.00296
H7_ENTROPIONEntropion and trichiasis of eyelidUK Biobank (UKBB)Neale Lab20185523606423Brain - Spinal cord (cervical c-1): p = 0.03
Spleen: p = 0.06
Adipose - Visceral (Omentum): p = 0.10
G6_INTRACRATRAUMAIntracranial traumaUK Biobank (UKBB)Neale Lab20188263603683Artery - Tibial: p = 0.00562
Spleen: p = 0.00833
Esophagus - Gastroesophageal Junction: p = 0.02
K11_PERITONDiseases of peritoneumUK Biobank (UKBB)Neale Lab20187653604292Nerve - Tibial: p = 0.04
Adrenal Gland: p = 0.07
Lung: p = 0.10
M13_RHEUMATISMRheumatism, unspecifiedUK Biobank (UKBB)Neale Lab20181503610443Brain - Cortex: p = 0.03
Brain - Frontal Cortex (BA9): p = 0.03
Esophagus - Gastroesophageal Junction: p = 0.03
L12_ACTINKERAActinic keratosisUK Biobank (UKBB)Neale Lab201813493598454Pituitary: p = 0.00274
Testis: p = 0.01
Esophagus - Mucosa: p = 0.02
C_PROSTATEMalignant neoplasm of prostateUK Biobank (UKBB)Neale Lab201863213548735Prostate: p = 1.85E-4
Minor Salivary Gland: p = 3.02E-4
Colon - Transverse: p = 6.63E-4
H7_STRABNASOther specified and unspecified strabismusUK Biobank (UKBB)Neale Lab20182293609652Spleen: p = 0.00889
Adipose - Visceral (Omentum): p = 0.03
Adipose - Subcutaneous: p = 0.06
L12_ERYTH_NASOther and unspecified erythematous conditionsUK Biobank (UKBB)Neale Lab20181083610862Prostate: p = 0.00182
Breast - Mammary Tissue: p = 0.00603
Lung: p = 0.03
L12_NAILDISNail disordersUK Biobank (UKBB)Neale Lab20189193602753Colon - Sigmoid: p = 0.02
Vagina: p = 0.04
Brain - Frontal Cortex (BA9): p = 0.04
M13_RECUDISLOCATIORecurrent dislocation and subluxation of jointUK Biobank (UKBB)Neale Lab20182063609882Whole Blood: p = 3.46E-5
Vagina: p = 0.00795
Skin - Not Sun Exposed (Suprapubic): p = 0.02
M13_SACROCOGGSacrococcygeal disorders, not elsewhere classifiedUK Biobank (UKBB)Neale Lab20183003608943Heart - Atrial Appendage: p = 0.00603
Heart - Left Ventricle: p = 0.01
Kidney - Cortex: p = 0.01
M13_TRIGGERFINGERTrigger fingerUK Biobank (UKBB)Neale Lab201819993591953Artery - Coronary: p = 8.25E-4
Artery - Aorta: p = 0.00385
Colon - Transverse: p = 0.00481
I9_CARDMYOCardiomyopathyUK Biobank (UKBB)Neale Lab20184213607733Breast - Mammary Tissue: p = 0.00349
Esophagus - Muscularis: p = 0.0064
Testis: p = 0.01
K11_HERNIAHerniaUK Biobank (UKBB)Neale Lab2018261973349975Spleen: p = 0.00106
Esophagus - Gastroesophageal Junction: p = 0.00172
Prostate: p = 0.00172
M13_RHEUMARheumatoid arthritisUK Biobank (UKBB)Neale Lab201816053595895Spleen: p = 1.22E-8
Lung: p = 1.47E-6
Whole Blood: p = 0.00224
C3_PRIMARY_LYMPHOID_HEMATOPOIETICPrimary_lymphoid and hematopoietic malignant neoplasmsUK Biobank (UKBB)Neale Lab201827103584844Spleen: p = 7.18E-4
Lung: p = 0.00162
Whole Blood: p = 0.00351
C3_SECONDARY_WITHOUT_SITESPECMalignant neoplasm, without specification of siteUK Biobank (UKBB)Neale Lab20181453610492Muscle - Skeletal: p = 0.02
Liver: p = 0.07
Pituitary: p = 0.07
M13_BONEDISNASOther specified/unspecified disorders of bone/cartilageUK Biobank (UKBB)Neale Lab20188623603323Colon - Sigmoid: p = 0.00713
Thyroid: p = 0.01
Artery - Coronary: p = 0.02
H7_GLAUCCLOSEPRIMPrimary angle-closure glaucomaUK Biobank (UKBB)Neale Lab20184623607323Whole Blood: p = 0.00444
Colon - Transverse: p = 0.02
Stomach: p = 0.02
F5_ANXIETYOther anxiety disordersUK Biobank (UKBB)Neale Lab20183523608422Minor Salivary Gland: p = 5.39E-4
Esophagus - Mucosa: p = 0.00414
Stomach: p = 0.01
C_THYROID_GLANDMalignant neoplasm of thyroid glandUK Biobank (UKBB)Neale Lab20183943608003Colon - Transverse: p = 0.01
Vagina: p = 0.02
Minor Salivary Gland: p = 0.04
H8_OTHHEARINGLOSSOther hearing lossUK Biobank (UKBB)Neale Lab20184133607813Heart - Left Ventricle: p = 0.00843
Skin - Not Sun Exposed (Suprapubic): p = 0.03
Colon - Transverse: p = 0.05
M13_JOINTOTHOther specific joint derangements/joint disordersUK Biobank (UKBB)Neale Lab201879433532513Skin - Not Sun Exposed (Suprapubic): p = 0.02
Brain - Cortex: p = 0.06
Brain - Nucleus accumbens (basal ganglia): p = 0.06
I9_STRStroke, excluding SAHUK Biobank (UKBB)Neale Lab201838323573623Adipose - Subcutaneous: p = 0.00402
Adipose - Visceral (Omentum): p = 0.00402
Vagina: p = 0.00625
H8_MED_SUPPSuppurative and unspecified otitis mediaUK Biobank (UKBB)Neale Lab20184863607083Brain - Cerebellar Hemisphere: p = 0.02
Brain - Cerebellum: p = 0.02
Brain - Substantia nigra: p = 0.02
E4_NUTRIDEFOther nutritional deficienciesUK Biobank (UKBB)Neale Lab20182163609783Brain - Cerebellar Hemisphere: p = 0.002
Brain - Cerebellum: p = 0.00321
Muscle - Skeletal: p = 0.02
XIX_INJURY_POISONInjury, poisoning and certain other consequences of external causesUK Biobank (UKBB)Neale Lab2018447963163983Esophagus - Gastroesophageal Junction: p = 0.01
Brain - Cerebellum: p = 0.01
Brain - Frontal Cortex (BA9): p = 0.03
I9_CARDMPRICardiomyopathies, Primary/intrinsicUK Biobank (UKBB)Neale Lab20183603608343Nerve - Tibial: p = 0.00324
Pancreas: p = 0.00678
Kidney - Cortex: p = 0.03
XVIII_MISCFINDINGSSymptoms, signs and abnormal clinical and laboratory findings, not elsewhere classifiedUK Biobank (UKBB)Neale Lab2018976022635924Thyroid: p = 0.00363
Lung: p = 0.02
Brain - Cerebellum: p = 0.02
M13_DUPUTRYENPalmar fascial fibromatosis [Dupuytren]UK Biobank (UKBB)Neale Lab201829483582465Artery - Tibial: p = 0.00135
Colon - Sigmoid: p = 0.00138
Esophagus - Muscularis: p = 0.00249
C3_CONNECTIVE_SOFT_NASMalignant neoplasm of other connective and soft tissueUK Biobank (UKBB)Neale Lab20182373609573Adrenal Gland: p = 0.00176
Kidney - Cortex: p = 0.0074
Vagina: p = 0.01
H7_VITRBODYGLOBEDisorders of vitreous bodyUK Biobank (UKBB)Neale Lab20184773607173Liver: p = 0.03
Small Intestine - Terminal Ileum: p = 0.06
Prostate: p = 0.07
C_FOLLICULAR_LYMPHOMAFollicular lymphomaUK Biobank (UKBB)Neale Lab20183653608293Spleen: p = 1.53E-4
Lung: p = 0.00385
Skin - Sun Exposed (Lower leg): p = 0.02
C_BREAST_3Malignant neoplasm of breastUK Biobank (UKBB)Neale Lab201897213514735Breast - Mammary Tissue: p = 9.01E-6
Artery - Coronary: p = 1.42E-4
Artery - Tibial: p = 1.42E-4
C_TNK_LYMPHOMAMature T/NK-cell lymphomasUK Biobank (UKBB)Neale Lab20181343610603Thyroid: p = 0.02
Brain - Hippocampus: p = 0.03
Stomach: p = 0.04
M13_CERVICALGIACervicalgiaUK Biobank (UKBB)Neale Lab201810493601453Nerve - Tibial: p = 0.0032
Brain - Cerebellum: p = 0.00889
Esophagus - Gastroesophageal Junction: p = 0.03
C_HODGKIN_LYMPHOMAHodgkin lymphomaUK Biobank (UKBB)Neale Lab20182483609463Testis: p = 0.01
Brain - Cortex: p = 0.06
Brain - Anterior cingulate cortex (BA24): p = 0.08
ENDOMETRIOSIS_NOSUnsepcified/other endometriosisUK Biobank (UKBB)Neale Lab20184343607603Stomach: p = 0.03
Pituitary: p = 0.04
Brain - Spinal cord (cervical c-1): p = 0.07
H7_KERATITISKeratitisUK Biobank (UKBB)Neale Lab20181823610123Whole Blood: p = 0.02
Artery - Aorta: p = 0.02
Liver: p = 0.02
E4_DM1OPTHType 1 diabetes with ophthalmic complicationsUK Biobank (UKBB)Neale Lab20181663610285Spleen: p = 2.51E-8
Lung: p = 2.76E-6
Whole Blood: p = 5.37E-4
CHRONSMALLCrohn's disease of small interstineUK Biobank (UKBB)Neale Lab20182493609453Ovary: p = 0.00308
Skin - Not Sun Exposed (Suprapubic): p = 0.01
Skin - Sun Exposed (Lower leg): p = 0.01
RHEUMA_CHRYSTALChrystal arthropathies, rheuma endpointUK Biobank (UKBB)Neale Lab20181033610912Skin - Sun Exposed (Lower leg): p = 0.02
Skin - Not Sun Exposed (Suprapubic): p = 0.03
Kidney - Cortex: p = 0.06
DM_PERIPHATHEROPeripheral atherosclerosisUK Biobank (UKBB)Neale Lab20185043606903Uterus: p = 0.01
Brain - Nucleus accumbens (basal ganglia): p = 0.03
Heart - Atrial Appendage: p = 0.05
H7_CORNEALOTHOther disorders of corneaUK Biobank (UKBB)Neale Lab20183143608803Adipose - Subcutaneous: p = 0.00917
Adipose - Visceral (Omentum): p = 0.04
Thyroid: p = 0.05
C3_URINARY_TRACTMalignant neoplasm of urinary organsUK Biobank (UKBB)Neale Lab201818413593533Brain - Cerebellar Hemisphere: p = 0.02
Brain - Spinal cord (cervical c-1): p = 0.02
Colon - Transverse: p = 0.02
PNEUMOBACTKNOWNBacterial pneumonia (organism specified)UK Biobank (UKBB)Neale Lab20185293606653Kidney - Cortex: p = 0.00572
Skin - Not Sun Exposed (Suprapubic): p = 0.01
Esophagus - Mucosa: p = 0.02
K11_GASTRODUOULCGastroduodenal ulcerUK Biobank (UKBB)Neale Lab201834673577273Pituitary: p = 0.00466
Esophagus - Mucosa: p = 0.00943
Ovary: p = 0.02
COLITNONINFNASNoninfectious colitis NASUK Biobank (UKBB)Neale Lab201889453522493Uterus: p = 0.01
Brain - Cerebellar Hemisphere: p = 0.04
Brain - Cerebellum: p = 0.04
E4_DM2Type 2 diabetesUK Biobank (UKBB)Neale Lab20188883603063Lung: p = 8.25E-4
Whole Blood: p = 0.01
Breast - Mammary Tissue: p = 0.02
L12_HYPERTROPHICSKINHypertrophic disorders of skinUK Biobank (UKBB)Neale Lab20186293605653Artery - Tibial: p = 0.01
Artery - Aorta: p = 0.03
Brain - Spinal cord (cervical c-1): p = 0.03
H8_CERUMENImpacted cerumenUK Biobank (UKBB)Neale Lab20181613610333Ovary: p = 0.00421
Minor Salivary Gland: p = 0.01
Nerve - Tibial: p = 0.04
H7_LENSDisorders of lensUK Biobank (UKBB)Neale Lab2018170763441185Spleen: p = 6.24E-5
Nerve - Tibial: p = 0.00159
Whole Blood: p = 0.0033
E4_THYTOXGOITDIFThyrotoxicosis with diffuse goitrUK Biobank (UKBB)Neale Lab20181583610365Lung: p = 3.72E-6
Spleen: p = 7.52E-6
Small Intestine - Terminal Ileum: p = 0.00272
L12_OTHPIGMENTATIONOther disorders of pigmentationUK Biobank (UKBB)Neale Lab20185253606693Nerve - Tibial: p = 0.01
Vagina: p = 0.01
Small Intestine - Terminal Ileum: p = 0.02
K11_OESULCUlcer of oesophagusUK Biobank (UKBB)Neale Lab201830983580963Thyroid: p = 0.00619
Brain - Spinal cord (cervical c-1): p = 0.00751
Brain - Substantia nigra: p = 0.01
L12_FOLICULAROTHOther follicular disordersUK Biobank (UKBB)Neale Lab20182503609443Adipose - Visceral (Omentum): p = 8.61E-4
Brain - Spinal cord (cervical c-1): p = 0.00222
Adipose - Subcutaneous: p = 0.00534
M13_DORSALGIANASOther/unspecified dorsalgiaUK Biobank (UKBB)Neale Lab201821183590763Liver: p = 0.00312
Thyroid: p = 0.01
Minor Salivary Gland: p = 0.03
C_BRONCHUS_LUNGMalignant neoplasm of bronchus and lungUK Biobank (UKBB)Neale Lab201816813595133Colon - Transverse: p = 0.02
Artery - Aorta: p = 0.02
Esophagus - Gastroesophageal Junction: p = 0.02
G6_NEUINFLInflammatory diseases of the central nervous systemUK Biobank (UKBB)Neale Lab20183053608892Vagina: p = 0.02
Adipose - Visceral (Omentum): p = 0.08
Skin - Not Sun Exposed (Suprapubic): p = 0.08
C_OTHER_SKINOther malignant neoplasms of skinUK Biobank (UKBB)Neale Lab2018144023467925Spleen: p = 1.27E-5
Skin - Sun Exposed (Lower leg): p = 6.58E-4
Skin - Not Sun Exposed (Suprapubic): p = 0.00133
I9_CONDUCTIOConduction disordersUK Biobank (UKBB)Neale Lab201810553601393Colon - Transverse: p = 2.45E-4
Heart - Left Ventricle: p = 0.02
Stomach: p = 0.03
PULMONARYDGOther pulmonary diagnosisUK Biobank (UKBB)Neale Lab2018253813358134Lung: p = 8.22E-5
Whole Blood: p = 0.00177
Pituitary: p = 0.0096
C_RECTOISIGMOID_JUNCTIONMalignant neoplasm of rectosigmoid junctionUK Biobank (UKBB)Neale Lab20183333608613Muscle - Skeletal: p = 0.00212
Ovary: p = 0.01
Breast - Mammary Tissue: p = 0.03
H8_HL_SEN_NASSensorineural hearing lossUK Biobank (UKBB)Neale Lab20181043610903Pituitary: p = 0.00414
Pancreas: p = 0.01
Prostate: p = 0.01
F5_PERSONALITYSpecific personality disordersUK Biobank (UKBB)Neale Lab20181283610663Esophagus - Mucosa: p = 0.02
Adrenal Gland: p = 0.04
Muscle - Skeletal: p = 0.05
C3_BLADDERMalignant neoplasm of bladderUK Biobank (UKBB)Neale Lab20188903603043Spleen: p = 3.28E-5
Adipose - Visceral (Omentum): p = 0.00197
Whole Blood: p = 0.00385
K11_ACUTGASTRAcute gastritisUK Biobank (UKBB)Neale Lab20185943606002Minor Salivary Gland: p = 8.56E-4
Esophagus - Mucosa: p = 0.00708
Stomach: p = 0.01
C3_ENDOCRINEMalignant neoplasm of endocrine glandUK Biobank (UKBB)Neale Lab20184293607653Adipose - Subcutaneous: p = 0.01
Lung: p = 0.02
Vagina: p = 0.04
C3_KIDNEY_NOTRENALPELVISMalignant neoplasm of kidney, except renal pelvisUK Biobank (UKBB)Neale Lab20188713603233Uterus: p = 0.00106
Colon - Transverse: p = 0.00453
Muscle - Skeletal: p = 0.01
K11_IMPACTImpaction of intestinesUK Biobank (UKBB)Neale Lab20181253610692Pancreas: p = 0.0031
Small Intestine - Terminal Ileum: p = 0.01
Adipose - Subcutaneous: p = 0.03
C_STROKESTROKEUK Biobank (UKBB)Neale Lab201861463550483Brain - Cerebellum: p = 0.00978
Brain - Cerebellar Hemisphere: p = 0.02
Liver: p = 0.04
M13_CARTILAGEOther articular cartilage disordersUK Biobank (UKBB)Neale Lab20183533608412Skin - Sun Exposed (Lower leg): p = 0.00342
Skin - Not Sun Exposed (Suprapubic): p = 0.01
Adipose - Visceral (Omentum): p = 0.03
H8_PERCHRONDRPerichondritis of external earUK Biobank (UKBB)Neale Lab20182743609202Muscle - Skeletal: p = 0.04
Brain - Spinal cord (cervical c-1): p = 0.05
Pituitary: p = 0.10
C3_ANUS_ANALCANALMalignant neoplasm of anus and anal canalUK Biobank (UKBB)Neale Lab20181273610675Lung: p = 4.27E-6
Skin - Sun Exposed (Lower leg): p = 1.98E-4
Whole Blood: p = 5.8E-4
I9_STR_SAHStroke, including SAHUK Biobank (UKBB)Neale Lab201844843567103Brain - Cerebellum: p = 4.5E-5
Brain - Cerebellar Hemisphere: p = 0.00186
Pituitary: p = 0.02
H7_DIPLOPIADiplopiaUK Biobank (UKBB)Neale Lab20181833610113Lung: p = 0.01
Testis: p = 0.01
Esophagus - Muscularis: p = 0.03
PULM_ANXIETYAnxiety (asthma-related co-morbidities)UK Biobank (UKBB)Neale Lab20185323606623Adrenal Gland: p = 0.00196
Minor Salivary Gland: p = 0.00511
Uterus: p = 0.01
ILD_DIFF_DGILD differential diagnosisUK Biobank (UKBB)Neale Lab2018267103344844Whole Blood: p = 6.56E-4
Lung: p = 0.00192
Colon - Transverse: p = 0.00601
GOUTGout, FINNGENUK Biobank (UKBB)Neale Lab20183443608503Esophagus - Gastroesophageal Junction: p = 0.00377
Heart - Atrial Appendage: p = 0.00377
Colon - Sigmoid: p = 0.00592
C3_LARYNXMalignant neoplasm of larynxUK Biobank (UKBB)Neale Lab20182053609893Adrenal Gland: p = 0.01
Prostate: p = 0.03
Brain - Hypothalamus: p = 0.05
CHILDHOOD_ALLERGYChildhood allergy (age < 16)UK Biobank (UKBB)Neale Lab20181413610533Kidney - Cortex: p = 0.00209
Colon - Sigmoid: p = 0.00259
Esophagus - Muscularis: p = 0.00259
BACT_INTEST_INFECTION_NOSOther specified/unspecified bacterial intestinal infectionsUK Biobank (UKBB)Neale Lab20184533607412Brain - Putamen (basal ganglia): p = 0.02
Thyroid: p = 0.03
Brain - Caudate (basal ganglia): p = 0.03
M13_LOWBACKPAINLow back painUK Biobank (UKBB)Neale Lab201854233557713Uterus: p = 0.00321
Brain - Cerebellum: p = 0.00754
Brain - Cerebellar Hemisphere: p = 0.01
C_SECONDARY_WITHOUT_SITESPECMalignant neoplasm, without specification of siteUK Biobank (UKBB)Neale Lab20181453610492Muscle - Skeletal: p = 0.02
Liver: p = 0.07
Pituitary: p = 0.07
C_UNCERTAIN_SECONDARYNAUK Biobank (UKBB)Neale Lab20184233607713Vagina: p = 0.00222
Brain - Hypothalamus: p = 0.00974
Colon - Sigmoid: p = 0.00974
C3_TONSILMalignant neoplasm of tonsilUK Biobank (UKBB)Neale Lab20181753610193Lung: p = 0.00259
Spleen: p = 0.00599
Whole Blood: p = 0.00727
I9_CORATHERCoronary atherosclerosisUK Biobank (UKBB)Neale Lab2018143343468605Artery - Coronary: p = 3.31E-5
Adipose - Subcutaneous: p = 4.2E-4
Artery - Tibial: p = 6.56E-4
M13_OLECRANONBURSITISOlecranon bursitisUK Biobank (UKBB)Neale Lab20182853609093Colon - Transverse: p = 0.00678
Whole Blood: p = 0.01
Artery - Tibial: p = 0.02
XXI_HEALTHFACTORSFactors influencing health status and contact with health servicesUK Biobank (UKBB)Neale Lab2018459473152473Lung: p = 2.62E-5
Adipose - Subcutaneous: p = 0.01
Muscle - Skeletal: p = 0.01
H7_RETINALDETACHOTHOther, unspecified and serous retinal detachmentsUK Biobank (UKBB)Neale Lab20189233602713Small Intestine - Terminal Ileum: p = 0.00412
Spleen: p = 0.00414
Uterus: p = 0.03
L12_OTHERDISSKINANDSUBCUTISOther disorders of skin and subcutaneous tissue, not elsewhere classifiedUK Biobank (UKBB)Neale Lab201841473570473Colon - Sigmoid: p = 0.00224
Heart - Left Ventricle: p = 0.00308
Pancreas: p = 0.02
KRA_PSY_SUBSTANCESubstance abuseUK Biobank (UKBB)Neale Lab20188323603623Lung: p = 5.62E-4
Artery - Aorta: p = 0.02
Kidney - Cortex: p = 0.02
CONGEN_HEART_ARTERCongenital malformations of heart and great arteriesUK Biobank (UKBB)Neale Lab20184273607672Brain - Substantia nigra: p = 0.0089
Brain - Amygdala: p = 0.03
Brain - Cortex: p = 0.03
C_TONGUENASMalignant neoplasm of other and unspecified parts of tongueUK Biobank (UKBB)Neale Lab20181603610343Muscle - Skeletal: p = 0.01
Brain - Cerebellar Hemisphere: p = 0.02
Brain - Cerebellum: p = 0.03
C_LIVER_INTRAHEPATIC_BILE_DUCTSMalignant neoplasm of liver and intrahepatic bile ductsUK Biobank (UKBB)Neale Lab20182043609903Nerve - Tibial: p = 3.45E-5
Adrenal Gland: p = 0.00153
Ovary: p = 0.009
VIT_DEFVitamin deficiencyUK Biobank (UKBB)Neale Lab20181133610813Artery - Aorta: p = 0.02
Heart - Atrial Appendage: p = 0.04
Uterus: p = 0.05
C3_LIP_ORAL_PHARYNXMalignant neoplasm of lip, oral cavity and pharynxUK Biobank (UKBB)Neale Lab20187903604043Lung: p = 4.22E-4
Spleen: p = 0.01
Thyroid: p = 0.01
HEARTFAILHeart failureUK Biobank (UKBB)Neale Lab201814053597893Pancreas: p = 7.21E-4
Prostate: p = 0.00285
Stomach: p = 0.00492
M13_SPINSTENOSISSpinal stenosisUK Biobank (UKBB)Neale Lab201819103592843Brain - Substantia nigra: p = 0.02
Adipose - Visceral (Omentum): p = 0.03
Small Intestine - Terminal Ileum: p = 0.06
XX_EXTERNAL_MORB_MORTExternal causes of morbidity and mortalityUK Biobank (UKBB)Neale Lab20183503608443Small Intestine - Terminal Ileum: p = 0.02
Skin - Not Sun Exposed (Suprapubic): p = 0.04
Skin - Sun Exposed (Lower leg): p = 0.04
L12_FOLLICULARNASOther and unspecified follicular disordersUK Biobank (UKBB)Neale Lab20181073610873Adipose - Visceral (Omentum): p = 1.89E-4
Heart - Atrial Appendage: p = 0.03
Whole Blood: p = 0.03
M13_ARTHROSIS_OTHOther arthrosisUK Biobank (UKBB)Neale Lab201851683560263Ovary: p = 0.02
Breast - Mammary Tissue: p = 0.02
Stomach: p = 0.04
L12_ROSACEARosaceaUK Biobank (UKBB)Neale Lab20181113610833Spleen: p = 0.00352
Nerve - Tibial: p = 0.00696
Artery - Tibial: p = 0.04
H7_RETINALDETACHBREAKRetinal detachment with retinal breakUK Biobank (UKBB)Neale Lab201811983599963Adipose - Subcutaneous: p = 0.00299
Skin - Sun Exposed (Lower leg): p = 0.00824
Adipose - Visceral (Omentum): p = 0.01
M13_ENTESOPATHYNASOther/unspecified enthesopathies, not elsewhere classifiedUK Biobank (UKBB)Neale Lab20181533610412Artery - Coronary: p = 0.04
Pancreas: p = 0.04
Vagina: p = 0.07
C3_BRAINMalignant neoplasm of brainUK Biobank (UKBB)Neale Lab20183753608193Artery - Aorta: p = 0.02
Esophagus - Mucosa: p = 0.03
Lung: p = 0.03
XII_SKIN_SUBCUTANDiseases of the skin and subcutaneous tissueUK Biobank (UKBB)Neale Lab2018270743341203Thyroid: p = 0.00132
Colon - Sigmoid: p = 0.00691
Esophagus - Gastroesophageal Junction: p = 0.01
C3_RESPIRATORY_INTRATHORACICMalignant neoplasm of respiratory system and intrathoracic organsUK Biobank (UKBB)Neale Lab201819443592503Colon - Transverse: p = 0.00205
Testis: p = 0.02
Artery - Aorta: p = 0.04
K11_ADHEIntestinal adhesions without obstructionUK Biobank (UKBB)Neale Lab20186443605502Adrenal Gland: p = 0.00145
Muscle - Skeletal: p = 0.01
Whole Blood: p = 0.02
K11_ILEUSParalytic ileus and intestinal obstructionUK Biobank (UKBB)Neale Lab201821023590923Adrenal Gland: p = 0.006
Liver: p = 0.01
Brain - Substantia nigra: p = 0.02
KRA_PSY_ANYMENTAL_SUICIDAny mental disorder, or suicide (or attempt)UK Biobank (UKBB)Neale Lab20181233610713Artery - Aorta: p = 0.00243
Breast - Mammary Tissue: p = 0.06
Artery - Tibial: p = 0.06
M13_OSTEOPOROSISOsteoporosisUK Biobank (UKBB)Neale Lab20189333602613Lung: p = 0.00302
Heart - Left Ventricle: p = 0.00472
Pancreas: p = 0.00472
H7_CONJUVASCOther conjunctival vascular disorders and cystsUK Biobank (UKBB)Neale Lab20181533610412Liver: p = 0.04
Heart - Atrial Appendage: p = 0.05
Muscle - Skeletal: p = 0.05
H8_HL_CON_NASConductive hearing loss, unspecifiedUK Biobank (UKBB)Neale Lab20181573610373Artery - Tibial: p = 3.39E-4
Vagina: p = 0.00169
Esophagus - Mucosa: p = 0.01
H8_VERTIGODisorders of vestibular function (Vertigo)UK Biobank (UKBB)Neale Lab20183693608252Liver: p = 0.00527
Muscle - Skeletal: p = 0.03
Ovary: p = 0.03
C3_OESOPHAGUSMalignant neoplasm of oesophagusUK Biobank (UKBB)Neale Lab20184973606973Prostate: p = 0.02
Esophagus - Mucosa: p = 0.03
Liver: p = 0.03
KNEE_ARTHROSISGonarthrosis [arthrosis of knee](FG)UK Biobank (UKBB)Neale Lab2018119003492945Muscle - Skeletal: p = 0.02
Heart - Left Ventricle: p = 0.03
Uterus: p = 0.03
H7_RETINAVASCRetinal vascular disordersUK Biobank (UKBB)Neale Lab20183203608742Brain - Cortex: p = 0.00145
Brain - Anterior cingulate cortex (BA24): p = 0.00917
Brain - Frontal Cortex (BA9): p = 0.00917
ULCERPROCTUlcerative proctitisUK Biobank (UKBB)Neale Lab20182963608983Liver: p = 0.03
Whole Blood: p = 0.03
Kidney - Cortex: p = 0.07
G6_ALSMotor neuron diseaseUK Biobank (UKBB)Neale Lab20181673610273Small Intestine - Terminal Ileum: p = 0.00222
Brain - Cerebellum: p = 0.00229
Prostate: p = 0.00308
H7_RETVASCNASOther and unspecified vascular occlusionsUK Biobank (UKBB)Neale Lab20182623609322Lung: p = 0.0018
Brain - Cortex: p = 0.00761
Adrenal Gland: p = 0.02
K11_APPENDOTHOther appendicitisUK Biobank (UKBB)Neale Lab20184263607683Prostate: p = 0.00206
Pancreas: p = 0.00639
Ovary: p = 0.02
COPD_EARLYANDLATERCOPD, early/later onsetUK Biobank (UKBB)Neale Lab201818973592974Spleen: p = 1.16E-4
Whole Blood: p = 0.00115
Pituitary: p = 0.00278
XV_PREGNANCY_BIRTHPregnancy, childbirth and the puerperiumUK Biobank (UKBB)Neale Lab2018119593492353Thyroid: p = 0.02
Spleen: p = 0.02
Colon - Transverse: p = 0.03
G6_NERPLEXNerve, nerve root and plexus disordersUK Biobank (UKBB)Neale Lab2018108983502964Brain - Cerebellar Hemisphere: p = 0.00224
Brain - Cerebellum: p = 0.00224
Liver: p = 0.00318
G6_MONOLOWOTHUNSOther and unspecified mononeuropathies of lower limbUK Biobank (UKBB)Neale Lab20181303610643Brain - Frontal Cortex (BA9): p = 0.00845
Adipose - Visceral (Omentum): p = 0.01
Thyroid: p = 0.02
IBD_VIRAL_HEPATITISViral hepatitis, IBD co-morbidityUK Biobank (UKBB)Neale Lab20182243609703Pituitary: p = 0.01
Spleen: p = 0.01
Heart - Atrial Appendage: p = 0.03
K11_PANCOTHOther diseases of pancreasUK Biobank (UKBB)Neale Lab20183803608142Skin - Not Sun Exposed (Suprapubic): p = 0.00599
Esophagus - Gastroesophageal Junction: p = 0.01
Pituitary: p = 0.01
H7_REFRAACCOMMODISDisorders of refraction and accommodationUK Biobank (UKBB)Neale Lab20181923610022Lung: p = 0.03
Minor Salivary Gland: p = 0.05
Brain - Caudate (basal ganglia): p = 0.06
F5_DEMENTIADementiaUK Biobank (UKBB)Neale Lab20181573610373Whole Blood: p = 0.01
Esophagus - Mucosa: p = 0.02
Liver: p = 0.02
L12_URTICARIAUrticariaUK Biobank (UKBB)Neale Lab20181513610432Lung: p = 4.79E-4
Adipose - Visceral (Omentum): p = 0.02
Skin - Not Sun Exposed (Suprapubic): p = 0.04
L12_PSORIASISPsoriasisUK Biobank (UKBB)Neale Lab20184873607075Lung: p = 7.14E-6
Whole Blood: p = 1.36E-4
Spleen: p = 5.22E-4
G6_SDHTRAUTraumatic subdural haemorrhageUK Biobank (UKBB)Neale Lab20182383609563Artery - Tibial: p = 0.00622
Artery - Coronary: p = 0.02
Esophagus - Gastroesophageal Junction: p = 0.02
I9_DISVEINLYMPHDiseases of veins, lymphatic vessels and lymph nodes, not elsewhere classifiedUK Biobank (UKBB)Neale Lab2018118673493275Lung: p = 6.74E-6
Adipose - Subcutaneous: p = 3.53E-4
Esophagus - Gastroesophageal Junction: p = 7.62E-4
C_BRAINMalignant neoplasm of brainUK Biobank (UKBB)Neale Lab20183753608193Artery - Aorta: p = 0.02
Esophagus - Mucosa: p = 0.03
Lung: p = 0.03
M13_ARTHRITISNASOhter specific/unspecified arthritisUK Biobank (UKBB)Neale Lab201810823601123Heart - Left Ventricle: p = 0.02
Esophagus - Mucosa: p = 0.02
Nerve - Tibial: p = 0.03
M13_MUSCLEDISNASOther specified disorders of muscleUK Biobank (UKBB)Neale Lab20182573609372Whole Blood: p = 2.45E-4
Brain - Frontal Cortex (BA9): p = 0.00212
Spleen: p = 0.00404
M13_MYALGIAMyalgiaUK Biobank (UKBB)Neale Lab20182943609003Brain - Cortex: p = 6.09E-4
Brain - Anterior cingulate cortex (BA24): p = 0.00103
Brain - Frontal Cortex (BA9): p = 0.00103
M13_CALCIFICTENDCalcific tendinitis of shoulderUK Biobank (UKBB)Neale Lab20181733610213Muscle - Skeletal: p = 0.00192
Uterus: p = 0.00603
Pituitary: p = 0.04
E4_DM1KETOType 1 diabetes with ketoacidosisUK Biobank (UKBB)Neale Lab20181683610265Spleen: p = 7.01E-7
Lung: p = 5.35E-6
Whole Blood: p = 8.56E-5
M13_ANKLEFOOTOther acquired deformities of ankle and footUK Biobank (UKBB)Neale Lab20181183610763Liver: p = 0.02
Spleen: p = 0.02
Artery - Tibial: p = 0.03
M13_IMPINGEMENTImpingement syndrome of shoulderUK Biobank (UKBB)Neale Lab201834203577743Esophagus - Mucosa: p = 0.00172
Prostate: p = 0.00275
Thyroid: p = 0.01
G6_ROOTPLEXOTHUNSOther and unspecified nerve root and plexus disorders, also in other diseasesUK Biobank (UKBB)Neale Lab20181643610303Kidney - Cortex: p = 9.38E-5
Liver: p = 0.00154
Ovary: p = 0.00651
M13_FIBROBLASTICFibroblastic disordersUK Biobank (UKBB)Neale Lab201831903580045Uterus: p = 0.00131
Artery - Tibial: p = 0.0021
Colon - Sigmoid: p = 0.00407
VII_EYE_ADNEXADiseases of the eye and adnexaUK Biobank (UKBB)Neale Lab2018298783313165Esophagus - Muscularis: p = 0.00185
Lung: p = 0.00185
Spleen: p = 0.00218
I9_MIMyocardial infarctionUK Biobank (UKBB)Neale Lab201870183541765Adipose - Visceral (Omentum): p = 4.92E-5
Liver: p = 1.74E-4
Adipose - Subcutaneous: p = 0.00154
C3_DIGESTIVE_ORGANSMalignant neoplasm of digestive organsUK Biobank (UKBB)Neale Lab201856903555043Skin - Sun Exposed (Lower leg): p = 0.00412
Skin - Not Sun Exposed (Suprapubic): p = 0.00618
Adipose - Subcutaneous: p = 0.02
E4_DM2PERIPHType 2 diabetes with peripheral circulatory complicationsUK Biobank (UKBB)Neale Lab20181273610673Skin - Not Sun Exposed (Suprapubic): p = 0.00761
Skin - Sun Exposed (Lower leg): p = 0.02
Adipose - Subcutaneous: p = 0.04
M13_SPONDYLINFLAMNASOther specified/unspecified inflammatory spondylopathiesUK Biobank (UKBB)Neale Lab20181163610783Pancreas: p = 0.00115
Kidney - Cortex: p = 0.00874
Small Intestine - Terminal Ileum: p = 0.02
H7_VITROTHOther and unspecified disorders of vitreous bodyUK Biobank (UKBB)Neale Lab20181343610602Artery - Coronary: p = 0.00246
Lung: p = 0.00438
Spleen: p = 0.00698
L12_NAIL_INGROWIngrowing nailUK Biobank (UKBB)Neale Lab20186803605143Heart - Left Ventricle: p = 0.03
Esophagus - Mucosa: p = 0.05
Breast - Mammary Tissue: p = 0.07
C3_PROSTATEMalignant neoplasm of prostateUK Biobank (UKBB)Neale Lab201863213548735Prostate: p = 1.85E-4
Minor Salivary Gland: p = 3.02E-4
Colon - Transverse: p = 6.63E-4
SLEEPSleep disorders (combined)UK Biobank (UKBB)Neale Lab201829513582433Adipose - Subcutaneous: p = 0.00115
Artery - Coronary: p = 0.00154
Kidney - Cortex: p = 0.00154
C3_FEMALE_GENITALmalignant neoplasm of female genital organsUK Biobank (UKBB)Neale Lab201826033585913Heart - Atrial Appendage: p = 0.00294
Heart - Left Ventricle: p = 0.01
Kidney - Cortex: p = 0.02
H8_MENIEREMznire diseaseUK Biobank (UKBB)Neale Lab20181223610723Breast - Mammary Tissue: p = 0.05
Adrenal Gland: p = 0.05
Esophagus - Gastroesophageal Junction: p = 0.07
M13_FINGERDEFORMDeformity of finger(s)UK Biobank (UKBB)Neale Lab20181773610173Liver: p = 0.00674
Vagina: p = 0.00674
Whole Blood: p = 0.04
M13_CONTRACTUREJOINTContracture of jointUK Biobank (UKBB)Neale Lab20181383610562Thyroid: p = 0.00845
Colon - Sigmoid: p = 0.01
Esophagus - Muscularis: p = 0.02
M13_ACHILLESTENDAchilles tendinitisUK Biobank (UKBB)Neale Lab20181623610323Esophagus - Gastroesophageal Junction: p = 0.00507
Esophagus - Muscularis: p = 0.03
Small Intestine - Terminal Ileum: p = 0.05
ASTHMA_PNEUMONIAAsthma-related pneumoniaUK Biobank (UKBB)Neale Lab201859003552943Lung: p = 0.00879
Breast - Mammary Tissue: p = 0.01
Minor Salivary Gland: p = 0.02
IBD_ENDOMETRIOSISEndometriosis, IBD co-morbidityUK Biobank (UKBB)Neale Lab201815163596783Adrenal Gland: p = 2.44E-4
Lung: p = 0.00225
Pituitary: p = 0.00333
G6_DISBROTHUNSDisorders of brain, other and unspecifiedUK Biobank (UKBB)Neale Lab20181273610673Pancreas: p = 0.02
Brain - Cortex: p = 0.04
Brain - Frontal Cortex (BA9): p = 0.04
L12_GRANULOMATOUSSKINGranulomatous disorders of skin and subcutaneous tissueUK Biobank (UKBB)Neale Lab20183583608363Prostate: p = 7.42E-4
Skin - Sun Exposed (Lower leg): p = 0.00678
Skin - Not Sun Exposed (Suprapubic): p = 0.03
H8_CHRON_SUPOTITISChronic suppurative otitis mediaUK Biobank (UKBB)Neale Lab20182053609893Skin - Sun Exposed (Lower leg): p = 0.02
Esophagus - Mucosa: p = 0.02
Brain - Nucleus accumbens (basal ganglia): p = 0.03
K11_OESOBSTOesophageal obstructionUK Biobank (UKBB)Neale Lab20189943602003Pancreas: p = 0.00543
Prostate: p = 0.00543
Ovary: p = 0.02
N14_GLOMERULARGlomerular diseasesUK Biobank (UKBB)Neale Lab20187053604892Colon - Sigmoid: p = 0.00866
Spleen: p = 0.02
Artery - Coronary: p = 0.04
II_NEOPLASMNeoplasmsUK Biobank (UKBB)Neale Lab2018701782910165Pancreas: p = 0.00324
Ovary: p = 0.03
Breast - Mammary Tissue: p = 0.06
G6_CPETALCerebral palsy and other paralytic syndromesUK Biobank (UKBB)Neale Lab20185843606102Uterus: p = 0.01
Kidney - Cortex: p = 0.04
Whole Blood: p = 0.13
H8_EXT_NASOtitis externa, unspecifiedUK Biobank (UKBB)Neale Lab20181643610303Liver: p = 0.05
Uterus: p = 0.05
Muscle - Skeletal: p = 0.06
KRA_PSY_DEMENTIAAny dementiaUK Biobank (UKBB)Neale Lab20182433609513Pituitary: p = 0.02
Liver: p = 0.03
Vagina: p = 0.04
TRAUMBRAIN_NONCONCUSsevere traumatic brain injury, does not include concussionUK Biobank (UKBB)Neale Lab20185633606312Heart - Atrial Appendage: p = 1.72E-4
Pancreas: p = 0.0025
Artery - Tibial: p = 0.00502
L12_DERMATITISNASOther and unspecified dermatitisUK Biobank (UKBB)Neale Lab20183473608472Skin - Sun Exposed (Lower leg): p = 0.05
Muscle - Skeletal: p = 0.09
Kidney - Cortex: p = 0.09
ASTHMA_EOSINOPHIL_SUGGSuggestive for eosinophilic asthmaUK Biobank (UKBB)Neale Lab201823023588925Lung: p = 1.53E-7
Spleen: p = 0.00164
Skin - Sun Exposed (Lower leg): p = 0.0027
XIV_GENITOURINARYDiseases of the genitourinary systemUK Biobank (UKBB)Neale Lab2018716202895745Uterus: p = 7.36E-4
Whole Blood: p = 0.00321
Small Intestine - Terminal Ileum: p = 0.0041
L12_NONIONRADISKINSkin changes due to chronic exposure to nonionizing radiationUK Biobank (UKBB)Neale Lab201815013596934Kidney - Cortex: p = 0.00414
Esophagus - Mucosa: p = 0.02
Pituitary: p = 0.03
H7_BLEPHAROCHALASISBlepharochalasisUK Biobank (UKBB)Neale Lab20184983606963Brain - Substantia nigra: p = 0.02
Ovary: p = 0.02
Small Intestine - Terminal Ileum: p = 0.03
L12_EPIDERMTHICKNASOther and unspecified epidermal thickeningUK Biobank (UKBB)Neale Lab20184133607812Brain - Cerebellar Hemisphere: p = 8.74E-4
Pancreas: p = 0.02
Brain - Cerebellum: p = 0.02
C3_MALE_GENITALmalignant neoplasm of male genital organsUK Biobank (UKBB)Neale Lab201867953543995Prostate: p = 1.89E-5
Minor Salivary Gland: p = 3.78E-5
Colon - Transverse: p = 3.73E-4
CARDIAC_ARRHYTMCardiac arrhytmias, COPD co-morbiditiesUK Biobank (UKBB)Neale Lab201888013523935Heart - Atrial Appendage: p = 2.17E-7
Heart - Left Ventricle: p = 6.79E-6
Muscle - Skeletal: p = 1.37E-5
C3_EYE_ADNEXAMalignant neoplasm of eye and adnexaUK Biobank (UKBB)Neale Lab20181153610792Adrenal Gland: p = 0.00209
Brain - Cortex: p = 0.00524
Brain - Amygdala: p = 0.00835
C_FEMALE_GENITALNAUK Biobank (UKBB)Neale Lab201826033585913Heart - Atrial Appendage: p = 0.00294
Heart - Left Ventricle: p = 0.01
Kidney - Cortex: p = 0.02
F5_PANICPanic disorderUK Biobank (UKBB)Neale Lab20181123610823Testis: p = 0.04
Pituitary: p = 0.04
Thyroid: p = 0.07
ADAlzheimer's diseaseUK Biobank (UKBB)Neale Lab20181193610752Small Intestine - Terminal Ileum: p = 0.00735
Liver: p = 0.02
Pituitary: p = 0.08
PRE_OR_ECLAMPSIAPre-eclampsia or eclampsiaUK Biobank (UKBB)Neale Lab20181943610002Pancreas: p = 0.00795
Brain - Hypothalamus: p = 0.02
Brain - Amygdala: p = 0.03
III_BLOOD_IMMUNDiseases of the blood and blood-forming organs and certain disorders involving the immune mechanismUK Biobank (UKBB)Neale Lab2018100953510995Spleen: p = 1.81E-9
Lung: p = 1.05E-7
Whole Blood: p = 5.4E-4
H7_EPIPHORAEpiphoraUK Biobank (UKBB)Neale Lab20185923606023Artery - Aorta: p = 0.00743
Brain - Caudate (basal ganglia): p = 0.01
Brain - Nucleus accumbens (basal ganglia): p = 0.01
F5_MOODMood [affective] disordersUK Biobank (UKBB)Neale Lab201815463596483Brain - Anterior cingulate cortex (BA24): p = 9.88E-5
Brain - Hypothalamus: p = 5.21E-4
Brain - Frontal Cortex (BA9): p = 0.00234
NEURODEGOTHOther degenerative diseases of the nervous systemUK Biobank (UKBB)Neale Lab20182423609524Small Intestine - Terminal Ileum: p = 2.51E-4
Liver: p = 0.00874
Adrenal Gland: p = 0.02
K11_GIBLEEDINGGI-bleedingUK Biobank (UKBB)Neale Lab201852353559593Brain - Anterior cingulate cortex (BA24): p = 0.04
Brain - Hippocampus: p = 0.04
Esophagus - Mucosa: p = 0.04
M13_MEDIALEPICONDMedial epicondylitisUK Biobank (UKBB)Neale Lab20181223610723Small Intestine - Terminal Ileum: p = 0.02
Muscle - Skeletal: p = 0.02
Nerve - Tibial: p = 0.05
M13_HAMMERTOEOther hammer toe(s) (acquired)UK Biobank (UKBB)Neale Lab20188383603563Whole Blood: p = 3.9E-4
Brain - Substantia nigra: p = 0.02
Muscle - Skeletal: p = 0.02
H7_GLAUCSUSPGlaucoma suspectUK Biobank (UKBB)Neale Lab20183563608383Adrenal Gland: p = 0.09
Vagina: p = 0.09
Pituitary: p = 0.13
L12_DERM_NASOther and unspecified dermatitisUK Biobank (UKBB)Neale Lab20183203608742Spleen: p = 0.02
Brain - Frontal Cortex (BA9): p = 0.03
Brain - Anterior cingulate cortex (BA24): p = 0.07
K11_CHRONGASTRChronic gastritisUK Biobank (UKBB)Neale Lab201817903594043Whole Blood: p = 0.00824
Lung: p = 0.01
Brain - Cortex: p = 0.02
J10_ASTHMAAsthmaUK Biobank (UKBB)Neale Lab201819933592015Lung: p = 9.81E-7
Spleen: p = 8.56E-5
Whole Blood: p = 0.00385
K11_LIVERDiseases of liverUK Biobank (UKBB)Neale Lab201816633595313Stomach: p = 0.03
Small Intestine - Terminal Ileum: p = 0.04
Adipose - Visceral (Omentum): p = 0.04
E4_OBESITYNASObesity, other/unspecifiedUK Biobank (UKBB)Neale Lab20184333607613Colon - Sigmoid: p = 0.00952
Ovary: p = 0.02
Liver: p = 0.03
C3_EYE_BRAIN_NEUROMalignant neoplasm of eye, brain and central nervous systemUK Biobank (UKBB)Neale Lab20185173606773Heart - Atrial Appendage: p = 0.00352
Small Intestine - Terminal Ileum: p = 0.00706
Lung: p = 0.0071
VIII_EAR_MASTOIDDiseases of the ear and mastoid processUK Biobank (UKBB)Neale Lab201852523559423Esophagus - Mucosa: p = 0.001
Stomach: p = 0.00396
Muscle - Skeletal: p = 0.00906
DM_KETOACIDOSISDiabetic ketoacidosisUK Biobank (UKBB)Neale Lab20182343609605Spleen: p = 5.57E-7
Lung: p = 2.5E-6
Whole Blood: p = 6.64E-5
KRA_PSY_PERSONPersonality disordersUK Biobank (UKBB)Neale Lab20181363610583Skin - Sun Exposed (Lower leg): p = 0.00333
Esophagus - Mucosa: p = 0.03
Skin - Not Sun Exposed (Suprapubic): p = 0.03
M13_NECROVASC#Other necrotizing vasculopathiesUK Biobank (UKBB)Neale Lab20183513608433Brain - Cortex: p = 0.0012
Spleen: p = 0.00199
Brain - Caudate (basal ganglia): p = 0.00319
H8_OTORRHOEAOtorrhoeaUK Biobank (UKBB)Neale Lab20181423610523Adrenal Gland: p = 0.03
Colon - Sigmoid: p = 0.04
Esophagus - Muscularis: p = 0.04
AB1_SEXUAL_TRANSMISSIONInfections with a predominantly sexual mode of transmissionUK Biobank (UKBB)Neale Lab20181363610584Whole Blood: p = 0.00149
Lung: p = 0.00843
Spleen: p = 0.03
I9_HEARTFAIL_NSHeart failure, not strictUK Biobank (UKBB)Neale Lab201814053597893Pancreas: p = 7.21E-4
Prostate: p = 0.00285
Stomach: p = 0.00492
I9_ARTEMBTHRArterial embolism and thrombosisUK Biobank (UKBB)Neale Lab20185783606163Thyroid: p = 6.68E-5
Esophagus - Mucosa: p = 0.00121
Pituitary: p = 0.00294
C_LARYNXMalignant neoplasm of larynxUK Biobank (UKBB)Neale Lab20182053609893Adrenal Gland: p = 0.01
Prostate: p = 0.03
Brain - Hypothalamus: p = 0.05
THYROTOXICOSISThyrotoxicosisUK Biobank (UKBB)Neale Lab20184223607725Lung: p = 1.51E-5
Spleen: p = 1.51E-5
Whole Blood: p = 1.88E-4
M13_HALLUDEFORMOTHOther deformity of hallux (acquired)UK Biobank (UKBB)Neale Lab20181353610593Adrenal Gland: p = 0.00255
Vagina: p = 0.00274
Esophagus - Mucosa: p = 0.05
H7_GLAUCNASOther and unspecified glaucomaUK Biobank (UKBB)Neale Lab20185733606213Nerve - Tibial: p = 0.01
Thyroid: p = 0.01
Artery - Coronary: p = 0.01
GOUT_NOSGout, unspecifiedUK Biobank (UKBB)Neale Lab20182923609023Heart - Atrial Appendage: p = 9.61E-4
Esophagus - Gastroesophageal Junction: p = 0.00625
Colon - Sigmoid: p = 0.04
XVII_MALFORMAT_ABNORMALCongenital malformations, deformations and chromosomal abnormalitiesUK Biobank (UKBB)Neale Lab201821213590733Spleen: p = 0.00299
Adrenal Gland: p = 0.00691
Prostate: p = 0.00721
DM_RETINOPAT_NOSUnclassified diabetic retinopathyUK Biobank (UKBB)Neale Lab20184623607325Lung: p = 1.84E-5
Spleen: p = 1.88E-4
Whole Blood: p = 1.88E-4
I9_IHDIschaemic heart disease, wide definitionUK Biobank (UKBB)Neale Lab2018208573403374Adipose - Subcutaneous: p = 9.58E-5
Adipose - Visceral (Omentum): p = 1.69E-4
Artery - Coronary: p = 5.01E-4
M13_DISSYNOTENDNASOther specified/unspecified disorders of synovium and tendon +Other specified/unspecified bursopathiesUK Biobank (UKBB)Neale Lab20183433608513Stomach: p = 0.00279
Kidney - Cortex: p = 0.01
Prostate: p = 0.03
I9_PADPeripheral artery diseaseUK Biobank (UKBB)Neale Lab201812303599643Uterus: p = 0.00109
Nerve - Tibial: p = 0.00517
Skin - Sun Exposed (Lower leg): p = 0.02
C_RESPIRATORY_INTRATHORACICNAUK Biobank (UKBB)Neale Lab201819443592503Colon - Transverse: p = 0.00205
Testis: p = 0.02
Artery - Aorta: p = 0.04
I9_HYPERTENSIONHypertensive diseasesUK Biobank (UKBB)Neale Lab201813133598813Adipose - Subcutaneous: p = 7.32E-4
Breast - Mammary Tissue: p = 0.0018
Small Intestine - Terminal Ileum: p = 0.00412
H7_VISUDISTURBVisual disturbancesUK Biobank (UKBB)Neale Lab20186113605833Lung: p = 0.00415
Small Intestine - Terminal Ileum: p = 0.03
Esophagus - Muscularis: p = 0.05
M13_TENDOSYNOVITISNASOther/unspecified synovitis and tenosynovitisUK Biobank (UKBB)Neale Lab20186293605653Esophagus - Mucosa: p = 0.02
Minor Salivary Gland: p = 0.07
Nerve - Tibial: p = 0.07
D3_OTHERBLOODOher diseases of blood and blood-forming organsUK Biobank (UKBB)Neale Lab20182943609002Kidney - Cortex: p = 0.05
Adipose - Subcutaneous: p = 0.08
Adipose - Visceral (Omentum): p = 0.08
C3_COLONMalignant neoplasm of colonUK Biobank (UKBB)Neale Lab201824373587573Thyroid: p = 1.24E-4
Whole Blood: p = 0.00292
Heart - Atrial Appendage: p = 0.02
C3_CERVIX_UTERIMalignant neoplasm of cervix uteriUK Biobank (UKBB)Neale Lab20183683608263Kidney - Cortex: p = 0.03
Liver: p = 0.03
Muscle - Skeletal: p = 0.03
AB1_VIRAL_HEPATITISViral hepatitisUK Biobank (UKBB)Neale Lab20182433609513Esophagus - Muscularis: p = 0.03
Pancreas: p = 0.05
Brain - Anterior cingulate cortex (BA24): p = 0.07
I9_NONRHEVALVNon-rheumatic valve diseasesUK Biobank (UKBB)Neale Lab201816063595883Artery - Aorta: p = 1.33E-5
Artery - Coronary: p = 2.49E-5
Artery - Tibial: p = 2.57E-4
I9_VTEVenous thromboembolismUK Biobank (UKBB)Neale Lab201846203565745Stomach: p = 1.21E-5
Liver: p = 7.25E-5
Kidney - Cortex: p = 3.13E-4
X_RESPIRATORYDiseases of the respiratory systemUK Biobank (UKBB)Neale Lab2018253813358134Lung: p = 8.22E-5
Whole Blood: p = 0.00177
Pituitary: p = 0.0096
D3_ANAEMIANASOther and unspecified anaemiasUK Biobank (UKBB)Neale Lab201842913569035Lung: p = 1.06E-4
Spleen: p = 1.44E-4
Liver: p = 0.00197
M13_SHOULDERBURSITISBursitis of shoulderUK Biobank (UKBB)Neale Lab20181593610353Minor Salivary Gland: p = 0.02
Brain - Cerebellar Hemisphere: p = 0.03
Lung: p = 0.03
DM_PERIPH_ANGIOPATHYPeripheral angiopathyUK Biobank (UKBB)Neale Lab20181813610133Lung: p = 0.00523
Spleen: p = 0.00792
Heart - Atrial Appendage: p = 0.02
C_OVARYMalignant neoplasm of ovaryUK Biobank (UKBB)Neale Lab20188443603502Kidney - Cortex: p = 3.8E-4
Pancreas: p = 0.04
Lung: p = 0.06
H7_CONVERSTRABConvergent concomitant strabismusUK Biobank (UKBB)Neale Lab20181383610563Skin - Sun Exposed (Lower leg): p = 6.27E-4
Skin - Not Sun Exposed (Suprapubic): p = 0.00175
Colon - Transverse: p = 0.00453
I9_RHEUFEVRheumatic fever incl heart diseaseUK Biobank (UKBB)Neale Lab20184343607603Liver: p = 0.00843
Adipose - Visceral (Omentum): p = 0.01
Heart - Atrial Appendage: p = 0.03
G6_TRINEUTrigeminal neuralgiaUK Biobank (UKBB)Neale Lab20181893610052Kidney - Cortex: p = 0.02
Adipose - Subcutaneous: p = 0.02
Adipose - Visceral (Omentum): p = 0.05
H7_EYELIDFUNCOther disorders affecting eyelid functionUK Biobank (UKBB)Neale Lab20181343610603Lung: p = 0.00231
Esophagus - Gastroesophageal Junction: p = 0.01
Stomach: p = 0.01
K11_BARRETBarret oesophagusUK Biobank (UKBB)Neale Lab201817913594033Spleen: p = 3.02E-4
Esophagus - Gastroesophageal Junction: p = 0.00331
Nerve - Tibial: p = 0.00433
G6_XTRAPYRExtrapyramidal and movement disordersUK Biobank (UKBB)Neale Lab20184803607143Skin - Sun Exposed (Lower leg): p = 2.57E-4
Skin - Not Sun Exposed (Suprapubic): p = 4.43E-4
Minor Salivary Gland: p = 0.01
LUNG_CANCER_MESOTLung cancer and mesotheliomaUK Biobank (UKBB)Neale Lab201820073591873Colon - Transverse: p = 0.00321
Brain - Cortex: p = 0.04
Brain - Frontal Cortex (BA9): p = 0.06
C3_SKINMalignant neoplasm of skinUK Biobank (UKBB)Neale Lab2018165313446635Spleen: p = 5.75E-7
Vagina: p = 7.71E-4
Lung: p = 0.0011
I9_AORTDISDissection of aortaUK Biobank (UKBB)Neale Lab20181293610653Ovary: p = 5.37E-5
Breast - Mammary Tissue: p = 0.00136
Colon - Sigmoid: p = 0.00356
KRA_PSY_ANYMENTALAny mental disorderUK Biobank (UKBB)Neale Lab201843043568903Brain - Putamen (basal ganglia): p = 9.2E-4
Prostate: p = 0.00183
Brain - Nucleus accumbens (basal ganglia): p = 0.00235
C3_TONGUENASMalignant neoplasm of other and unspecified parts of tongueUK Biobank (UKBB)Neale Lab20181603610343Muscle - Skeletal: p = 0.01
Brain - Cerebellar Hemisphere: p = 0.02
Brain - Cerebellum: p = 0.03
L12_OTHERMELANINOther melanin hyperpigmentationUK Biobank (UKBB)Neale Lab20183183608763Breast - Mammary Tissue: p = 0.02
Adipose - Visceral (Omentum): p = 0.03
Artery - Aorta: p = 0.04
E4_DMNASOPTHUnspecified diabetes with ophthalmic complicationsUK Biobank (UKBB)Neale Lab20181533610414Skin - Not Sun Exposed (Suprapubic): p = 0.00472
Whole Blood: p = 0.02
Skin - Sun Exposed (Lower leg): p = 0.02
M13_ENTESOPATHYFOOTOher enthesopathy of foot (+metatarsalgia)UK Biobank (UKBB)Neale Lab20182323609623Pancreas: p = 0.02
Brain - Nucleus accumbens (basal ganglia): p = 0.02
Heart - Left Ventricle: p = 0.02
D3_ITPIdiopathic thrombocytopenic purpuraUK Biobank (UKBB)Neale Lab20182073609873Breast - Mammary Tissue: p = 0.05
Nerve - Tibial: p = 0.05
Liver: p = 0.05
ULCERRECTUlcerative rectosigmoiditisUK Biobank (UKBB)Neale Lab20181603610343Esophagus - Gastroesophageal Junction: p = 0.01
Colon - Sigmoid: p = 0.04
Esophagus - Muscularis: p = 0.04
ENDOMETRIOSIS_PELVICPERITONEUMEndometriosis of pelvic peritoneumUK Biobank (UKBB)Neale Lab20182883609063Pituitary: p = 8.35E-5
Lung: p = 0.01
Skin - Not Sun Exposed (Suprapubic): p = 0.03
M13_SPONDYLOLISTHESISSpondylolisthesis/SpondylolysisUK Biobank (UKBB)Neale Lab20186403605543Pituitary: p = 9.41E-6
Thyroid: p = 3.49E-5
Stomach: p = 0.00113
CHRONNASChron's disease NASUK Biobank (UKBB)Neale Lab20187643604303Spleen: p = 5.83E-4
Whole Blood: p = 0.00115
Esophagus - Gastroesophageal Junction: p = 0.00732
VI_NERVOUSDiseases of the nervous systemUK Biobank (UKBB)Neale Lab2018213233398713Artery - Aorta: p = 0.00529
Brain - Hippocampus: p = 0.02
Prostate: p = 0.03
K11_OTHDIGOther diseases of the digestive systemUK Biobank (UKBB)Neale Lab201870633541315Spleen: p = 5.09E-8
Lung: p = 2.45E-7
Whole Blood: p = 7.44E-4
OTHER_SYSTCON_FGOther systemic involvement of connective tissue (FG)UK Biobank (UKBB)Neale Lab20182283609663Whole Blood: p = 0.00332
Adrenal Gland: p = 0.00488
Lung: p = 0.0055
OTHER_ILD_CVD_COMORBOther ILD-related CVD-co-morbiditiesUK Biobank (UKBB)Neale Lab201825073586874Liver: p = 1.05E-6
Colon - Transverse: p = 0.00145
Stomach: p = 0.00302
M13_TOEDEFORMOTHOther deformities of toe(s)UK Biobank (UKBB)Neale Lab20189673602273Brain - Spinal cord (cervical c-1): p = 0.00226
Brain - Hypothalamus: p = 0.00364
Brain - Cortex: p = 0.00574
H7_RETINANASOther specified and unspecified retinal disordersUK Biobank (UKBB)Neale Lab20184703607242Adipose - Subcutaneous: p = 6.34E-4
Breast - Mammary Tissue: p = 6.34E-4
Adrenal Gland: p = 0.00108
M13_CHRONDROPATHIESChrondropathiesUK Biobank (UKBB)Neale Lab20182913609033Artery - Tibial: p = 0.0059
Artery - Aorta: p = 0.00912
Esophagus - Gastroesophageal Junction: p = 0.01
SNORINGSnoringUK Biobank (UKBB)Neale Lab201813053598893Skin - Sun Exposed (Lower leg): p = 0.01
Skin - Not Sun Exposed (Suprapubic): p = 0.03
Spleen: p = 0.03
C3_BRONCHUS_LUNGMalignant neoplasm of bronchus and lungUK Biobank (UKBB)Neale Lab201816813595133Colon - Transverse: p = 0.02
Artery - Aorta: p = 0.02
Esophagus - Gastroesophageal Junction: p = 0.02
C_LYMPHNODES_SECONDARY_NASSecondary and unspecified malignant neoplasm of lymph nodesUK Biobank (UKBB)Neale Lab20181073610872Brain - Hypothalamus: p = 0.02
Brain - Substantia nigra: p = 0.03
Ovary: p = 0.05
C3_MESTOTHEL_SOFTTISSUEMelignant neoplasm of mesothelium and soft tissueUK Biobank (UKBB)Neale Lab20185143606803Stomach: p = 0.01
Brain - Cerebellum: p = 0.02
Kidney - Cortex: p = 0.02
M13_ADHCAPSULITISAdhesive capsulitis of shoulderUK Biobank (UKBB)Neale Lab201811983599963Minor Salivary Gland: p = 0.00246
Esophagus - Mucosa: p = 0.01
Brain - Anterior cingulate cortex (BA24): p = 0.01
H7_PTOSISPtosis of eyelidUK Biobank (UKBB)Neale Lab20189193602753Heart - Atrial Appendage: p = 1.24E-4
Heart - Left Ventricle: p = 0.02
Skin - Sun Exposed (Lower leg): p = 0.02
H7_LACRIMALSYSTEMDisorders of lacrimal systemUK Biobank (UKBB)Neale Lab201815553596393Uterus: p = 0.00332
Pituitary: p = 0.0051
Adrenal Gland: p = 0.03
ASTHMA_MODEAsthma (mode)UK Biobank (UKBB)Neale Lab20181973609973Muscle - Skeletal: p = 0.00978
Whole Blood: p = 0.02
Lung: p = 0.06
H7_CONJUNASOther specified and unspecified disorders of conjunctivaUK Biobank (UKBB)Neale Lab20181083610863Adipose - Visceral (Omentum): p = 0.04
Thyroid: p = 0.06
Pituitary: p = 0.08
RHEUMA_NOSOther/unspecified rheumatoid arthritisUK Biobank (UKBB)Neale Lab201812813599135Spleen: p = 7.89E-9
Lung: p = 5.16E-8
Small Intestine - Terminal Ileum: p = 0.00118
H8_EXTOTITISOtitis externaUK Biobank (UKBB)Neale Lab20183333608612Artery - Aorta: p = 0.01
Whole Blood: p = 0.02
Spleen: p = 0.05
I9_MI_STRICTMyocardial infarction, strictUK Biobank (UKBB)Neale Lab201870183541765Adipose - Visceral (Omentum): p = 4.92E-5
Liver: p = 1.74E-4
Adipose - Subcutaneous: p = 0.00154
RHEUMA_SEROPOSSeropositive rheumatoid arthritisUK Biobank (UKBB)Neale Lab20183273608675Lung: p = 8.01E-7
Spleen: p = 7.23E-6
Uterus: p = 0.02
I_INFECT_PARASITCertain infectious and parasitic diseasesUK Biobank (UKBB)Neale Lab201892973518973Artery - Aorta: p = 3.0E-4
Artery - Coronary: p = 7.39E-4
Uterus: p = 7.39E-4
H7_RETINALDISOTHOther retinal disordersUK Biobank (UKBB)Neale Lab201816923595023Thyroid: p = 0.00178
Artery - Aorta: p = 0.00418
Skin - Not Sun Exposed (Suprapubic): p = 0.03
ASTHMA_CHILDChildhood asthma (age<16)UK Biobank (UKBB)Neale Lab201819933592015Lung: p = 9.81E-7
Spleen: p = 8.56E-5
Whole Blood: p = 0.00385
HYPTENSPREGPregnancy hypertensionUK Biobank (UKBB)Neale Lab20187433604513Prostate: p = 0.00333
Vagina: p = 0.00333
Esophagus - Mucosa: p = 0.03
C_SECONDARY_RESPIRATORY_DIGESTIVESecondary malignant neoplasm of respiratory and digestive organsUK Biobank (UKBB)Neale Lab20181093610853Stomach: p = 0.02
Heart - Atrial Appendage: p = 0.12
Nerve - Tibial: p = 0.12
C3_MELANOMA_SKINMalignant melanoma of skinUK Biobank (UKBB)Neale Lab201825343586605Pituitary: p = 3.24E-4
Skin - Not Sun Exposed (Suprapubic): p = 0.02
Small Intestine - Terminal Ileum: p = 0.03
C_OESOPHAGUSMalignant neoplasm of oesophagusUK Biobank (UKBB)Neale Lab20184973606973Prostate: p = 0.02
Esophagus - Mucosa: p = 0.03
Liver: p = 0.03
SPONDYLOPATHY_FGSpondylopathies (FG)UK Biobank (UKBB)Neale Lab20183363608585Whole Blood: p = 2.04E-5
Spleen: p = 0.00103
Lung: p = 0.00255
M13_FOREIGNBODYResidual foreign body in soft tissueUK Biobank (UKBB)Neale Lab20182213609732Pancreas: p = 0.01
Artery - Coronary: p = 0.02
Artery - Aorta: p = 0.03
COX_ARTHROSISCoxarthrosis [arthrosis of hip](FG)UK Biobank (UKBB)Neale Lab201894103517845Colon - Sigmoid: p = 2.24E-4
Spleen: p = 2.24E-4
Artery - Coronary: p = 7.13E-4
K11_COELIACCoeliac diseaseUK Biobank (UKBB)Neale Lab20188423603525Spleen: p = 3.73E-9
Lung: p = 1.73E-5
Whole Blood: p = 3.89E-5
L12_LICHENSCLERATROPHLichen sclerosus et atrophicusUK Biobank (UKBB)Neale Lab20182703609242Lung: p = 0.02
Esophagus - Gastroesophageal Junction: p = 0.06
Uterus: p = 0.06
M13_SYNOTENDDisorders of synovium and tendonUK Biobank (UKBB)Neale Lab201858943553003Vagina: p = 6.24E-5
Heart - Left Ventricle: p = 0.01
Kidney - Cortex: p = 0.01
M13_PYOGARTHPyogenic arthritisUK Biobank (UKBB)Neale Lab20182783609163Spleen: p = 1.84E-6
Whole Blood: p = 1.65E-4
Uterus: p = 0.01
C_CONNECTIVE_SOFT_NASMalignant neoplasm of other connective and soft tissueUK Biobank (UKBB)Neale Lab20182373609573Adrenal Gland: p = 0.00176
Kidney - Cortex: p = 0.0074
Vagina: p = 0.01
M13_NEURALGIANeuralgia and neuritis, unspecifiedUK Biobank (UKBB)Neale Lab20182103609843Liver: p = 0.0075
Vagina: p = 0.02
Spleen: p = 0.03
ICDMAIN_ANY_ENTRYAny ICDMAIN event in hilmo or causes of deathUK Biobank (UKBB)Neale Lab2018282009791854Skin - Sun Exposed (Lower leg): p = 2.42E-4
Skin - Not Sun Exposed (Suprapubic): p = 3.64E-4
Small Intestine - Terminal Ileum: p = 0.00786
J10_EXTERLUNGLung diseases due to external agentsUK Biobank (UKBB)Neale Lab20182813609133Adipose - Visceral (Omentum): p = 0.00398
Lung: p = 0.02
Whole Blood: p = 0.02
C3_BREAST_3Malignant neoplasm of breastUK Biobank (UKBB)Neale Lab201897213514735Breast - Mammary Tissue: p = 9.01E-6
Artery - Coronary: p = 1.42E-4
Artery - Tibial: p = 1.42E-4
C_MELANOMA_SKINMalignant melanoma of skinUK Biobank (UKBB)Neale Lab201825343586605Pituitary: p = 3.24E-4
Skin - Not Sun Exposed (Suprapubic): p = 0.02
Small Intestine - Terminal Ileum: p = 0.03
H8_HL_NASOther specified/unspecified hearing lossUK Biobank (UKBB)Neale Lab20183973607973Colon - Transverse: p = 0.02
Pancreas: p = 0.05
Small Intestine - Terminal Ileum: p = 0.07
H7_HORDEOLUMHordeolum and other deep inflammation of eyelidUK Biobank (UKBB)Neale Lab20181043610903Esophagus - Gastroesophageal Junction: p = 0.02
Adipose - Subcutaneous: p = 0.04
Esophagus - Muscularis: p = 0.08
KRA_PSY_MOODMood disordersUK Biobank (UKBB)Neale Lab201815463596483Brain - Anterior cingulate cortex (BA24): p = 9.88E-5
Brain - Hypothalamus: p = 5.21E-4
Brain - Frontal Cortex (BA9): p = 0.00234
IBD_PULMRespiratory diseases principally affecting the interstitium, IBD co-morbiditesUK Biobank (UKBB)Neale Lab20184813607133Pancreas: p = 0.02
Spleen: p = 0.04
Liver: p = 0.07
ENDOMETRIOSIS_OVARYEndometriosis of ovaryUK Biobank (UKBB)Neale Lab20183863608083Adipose - Visceral (Omentum): p = 0.04
Skin - Not Sun Exposed (Suprapubic): p = 0.11
Adipose - Subcutaneous: p = 0.17
H7_CORNULCERCorneal ulcerUK Biobank (UKBB)Neale Lab20181023610923Stomach: p = 0.00441
Minor Salivary Gland: p = 0.00532
Skin - Sun Exposed (Lower leg): p = 0.02
SPONDYLOARTHRITISSpondyloarthritisUK Biobank (UKBB)Neale Lab20184643607304Whole Blood: p = 0.00191
Lung: p = 0.00532
Spleen: p = 0.00745
L12_NAILNASOther and unspecified nail disordersUK Biobank (UKBB)Neale Lab20181913610033Brain - Substantia nigra: p = 0.00349
Brain - Anterior cingulate cortex (BA24): p = 0.02
Brain - Cerebellar Hemisphere: p = 0.02
I9_DVTANDPULMDVT of lower extremities and pulmonary embolismUK Biobank (UKBB)Neale Lab201843193568755Stomach: p = 7.61E-6
Liver: p = 4.83E-5
Esophagus - Gastroesophageal Junction: p = 7.79E-4
H7_RETINALDETACHRetinal detachments and breaksUK Biobank (UKBB)Neale Lab201830433581514Artery - Aorta: p = 0.00139
Artery - Coronary: p = 0.00213
Uterus: p = 0.01
I9_CHD_NOREVMajor coronary heart disease event excluding revascularizationsUK Biobank (UKBB)Neale Lab2018101573510375Artery - Coronary: p = 2.72E-4
Artery - Tibial: p = 0.00135
Adipose - Visceral (Omentum): p = 0.00147
L12_SCARCONDITIONSScar conditions and fibrosis of skinUK Biobank (UKBB)Neale Lab201814763597182Adipose - Visceral (Omentum): p = 0.03
Uterus: p = 0.03
Liver: p = 0.05
AB1_VIRAL_SKIN_MUCOUS_MEMBRANEViral infections characterized by skin and mucous membrane lesionsUK Biobank (UKBB)Neale Lab20188583603363Stomach: p = 0.00152
Kidney - Cortex: p = 0.00352
Liver: p = 0.02
C_MYELOID LEUKAEMIAMyeloid leukaemiaUK Biobank (UKBB)Neale Lab20183143608802Kidney - Cortex: p = 0.00306
Esophagus - Mucosa: p = 0.00761
Brain - Nucleus accumbens (basal ganglia): p = 0.07
H7_RETINALBREAKRetinal breaks without detachmentUK Biobank (UKBB)Neale Lab20188183603763Brain - Anterior cingulate cortex (BA24): p = 0.02
Brain - Caudate (basal ganglia): p = 0.02
Brain - Cortex: p = 0.02
E4_DM2NOCOMPType 2 diabetes without complicationsUK Biobank (UKBB)Neale Lab20184543607403Colon - Transverse: p = 0.02
Ovary: p = 0.02
Lung: p = 0.03
C_RECTUMMalignant neoplasm of rectumUK Biobank (UKBB)Neale Lab201811703600243Whole Blood: p = 0.00497
Adrenal Gland: p = 0.01
Heart - Atrial Appendage: p = 0.02
H7_GLAUCPRIMOPENPrimary open-angle glaucomaUK Biobank (UKBB)Neale Lab20185303606643Kidney - Cortex: p = 0.00534
Lung: p = 0.00534
Brain - Cerebellum: p = 0.01
RHEUMA_SEROPOS_OTHOther/unspecified seropositiverheumatoid arthritisUK Biobank (UKBB)Neale Lab20182993608955Lung: p = 3.43E-7
Spleen: p = 9.63E-6
Ovary: p = 0.00943
M13_TROCHANTERICBURSITISTrochanteric bursitisUK Biobank (UKBB)Neale Lab20184443607503Colon - Sigmoid: p = 0.00671
Thyroid: p = 0.01
Brain - Hypothalamus: p = 0.03
C_SKINNAUK Biobank (UKBB)Neale Lab2018165313446635Spleen: p = 5.75E-7
Vagina: p = 7.71E-4
Lung: p = 0.0011
M13_LIMBPAINPain in limbUK Biobank (UKBB)Neale Lab201836743575203Liver: p = 8.47E-4
Thyroid: p = 0.00696
Adipose - Subcutaneous: p = 0.03
L12_LICHSIMPANDPRURIGOLichen simplex chronicus and prurigoUK Biobank (UKBB)Neale Lab20181273610673Artery - Aorta: p = 2.36E-4
Adipose - Subcutaneous: p = 0.00169
Artery - Coronary: p = 0.00396
H7_EYEOTHOther disorders of eye and adnexaUK Biobank (UKBB)Neale Lab20182303609643Artery - Tibial: p = 6.37E-4
Artery - Aorta: p = 0.00833
Brain - Substantia nigra: p = 0.02
C_BLADDERMalignant neoplasm of bladderUK Biobank (UKBB)Neale Lab20188903603043Spleen: p = 3.28E-5
Adipose - Visceral (Omentum): p = 0.00197
Whole Blood: p = 0.00385
M13_DORSALGIADorsalgiaUK Biobank (UKBB)Neale Lab201887993523954Pituitary: p = 0.00533
Pancreas: p = 0.02
Brain - Nucleus accumbens (basal ganglia): p = 0.03
L12_PSORI_NASOther and unspecified psoriasisUK Biobank (UKBB)Neale Lab20182063609885Lung: p = 2.53E-4
Pancreas: p = 0.00427
Skin - Not Sun Exposed (Suprapubic): p = 0.04
AB1_MYCOSESMycosesUK Biobank (UKBB)Neale Lab20184433607513Spleen: p = 4.34E-4
Whole Blood: p = 4.34E-4
Vagina: p = 8.61E-4
F5_BEHAVEBehavioural syndromes associated with physiological disturbances and physical factorsUK Biobank (UKBB)Neale Lab20181833610113Skin - Sun Exposed (Lower leg): p = 0.00287
Uterus: p = 0.00603
Esophagus - Mucosa: p = 0.01
C3_MESOTHELIOMAMesotheliomaUK Biobank (UKBB)Neale Lab20181653610293Artery - Tibial: p = 1.62E-5
Artery - Coronary: p = 0.00125
Artery - Aorta: p = 0.0032
G6_HYDROCEPHHydrocephalusUK Biobank (UKBB)Neale Lab20181133610812Brain - Cerebellar Hemisphere: p = 0.00426
Brain - Cerebellum: p = 0.0068
Spleen: p = 0.02
M13_BURSOPATHYOther bursopathiesUK Biobank (UKBB)Neale Lab20184013607933Minor Salivary Gland: p = 0.00432
Brain - Cerebellum: p = 0.02
Whole Blood: p = 0.02
M13_MUSCLEDisorders of musclesUK Biobank (UKBB)Neale Lab20184873607073Colon - Transverse: p = 2.57E-4
Small Intestine - Terminal Ileum: p = 0.00196
Spleen: p = 0.00508
H7_VITRHAEMORRVitreous haemorrhageUK Biobank (UKBB)Neale Lab20182563609383Uterus: p = 0.00278
Lung: p = 0.00738
Spleen: p = 0.01
C_LIP_ORAL_PHARYNXNAUK Biobank (UKBB)Neale Lab20187903604043Lung: p = 4.22E-4
Spleen: p = 0.01
Thyroid: p = 0.01
E4_DM2OPTHType 2 diabetes with ophthalmic complicationsUK Biobank (UKBB)Neale Lab20182363609583Heart - Atrial Appendage: p = 0.00178
Heart - Left Ventricle: p = 0.00456
Liver: p = 0.01
K11_CHRONPANCChronic pancreatitisUK Biobank (UKBB)Neale Lab20182463609483Artery - Aorta: p = 0.00115
Brain - Frontal Cortex (BA9): p = 0.0047
Brain - Caudate (basal ganglia): p = 0.00727
G6_ICTRAUOTHUNSOther and unspecified intracranial injuriesUK Biobank (UKBB)Neale Lab20181353610593Brain - Hypothalamus: p = 0.00312
Brain - Cortex: p = 0.00782
Brain - Anterior cingulate cortex (BA24): p = 0.01
H7_EYELIDDISOther disorders of eyelidUK Biobank (UKBB)Neale Lab201845293566653Brain - Caudate (basal ganglia): p = 0.02
Prostate: p = 0.02
Kidney - Cortex: p = 0.04
KRA_PSY_ALCOHAlcohol abuse, main dgUK Biobank (UKBB)Neale Lab20183223608722Skin - Not Sun Exposed (Suprapubic): p = 0.02
Skin - Sun Exposed (Lower leg): p = 0.02
Whole Blood: p = 0.02
E4_THYTOXNASThyrotoxicosis, other and/or unspecifiedUK Biobank (UKBB)Neale Lab20182403609544Lung: p = 2.76E-6
Whole Blood: p = 0.01
Spleen: p = 0.03
M13_SHOULDERNASOther shoulder lesionsUK Biobank (UKBB)Neale Lab20187403604542Skin - Not Sun Exposed (Suprapubic): p = 0.01
Kidney - Cortex: p = 0.02
Uterus: p = 0.04
SFNSmall fibre neuropathyUK Biobank (UKBB)Neale Lab20181433610513Ovary: p = 0.01
Brain - Amygdala: p = 0.02
Brain - Hypothalamus: p = 0.02
M13_BAKERCYSTSynovial cyst of popliteal space [Baker]UK Biobank (UKBB)Neale Lab20182233609713Heart - Atrial Appendage: p = 0.00255
Heart - Left Ventricle: p = 0.00255
Stomach: p = 0.02
C3_CORPUS_UTERIMalignant neoplasm of corpus uteriUK Biobank (UKBB)Neale Lab201812223599723Whole Blood: p = 0.005
Pituitary: p = 0.02
Spleen: p = 0.02
AB1_VIRAL_CNSViral infections of the central nervous systemUK Biobank (UKBB)Neale Lab20181973609973Brain - Spinal cord (cervical c-1): p = 0.00171
Vagina: p = 0.02
Esophagus - Mucosa: p = 0.02
D3_OTHERANAEMIAOther anaemiasUK Biobank (UKBB)Neale Lab201842943569005Lung: p = 9.08E-5
Spleen: p = 1.0E-4
Liver: p = 0.00122
L12_ATROPHICSKINAtrophic disorders of skinUK Biobank (UKBB)Neale Lab201817573594373Adrenal Gland: p = 0.00696
Uterus: p = 0.03
Adipose - Visceral (Omentum): p = 0.04
C_MALE_GENITALNAUK Biobank (UKBB)Neale Lab201867953543995Prostate: p = 1.89E-5
Minor Salivary Gland: p = 3.78E-5
Colon - Transverse: p = 3.73E-4
I9_ENDOCARDEndocarditisUK Biobank (UKBB)Neale Lab20182153609793Lung: p = 0.01
Brain - Substantia nigra: p = 0.02
Colon - Sigmoid: p = 0.02
C3_LYMPHNODES_SECONDARY_NASSecondary and unspecified malignant neoplasm of lymph nodesUK Biobank (UKBB)Neale Lab20181073610872Brain - Hypothalamus: p = 0.02
Brain - Substantia nigra: p = 0.03
Ovary: p = 0.05
DM_BCKGRND_RETINOPATBackground diabetic retinopathyUK Biobank (UKBB)Neale Lab20181083610862Kidney - Cortex: p = 0.0012
Vagina: p = 0.0012
Uterus: p = 0.00155
C3_TESTISMalignant neoplasm of testisUK Biobank (UKBB)Neale Lab20184323607624Esophagus - Gastroesophageal Junction: p = 0.03
Artery - Tibial: p = 0.05
Pancreas: p = 0.06
C_DIFFICILE_ENTEROCOLITISEnterocolitis due to Clostridium difficileUK Biobank (UKBB)Neale Lab20181843610102Muscle - Skeletal: p = 0.00444
Lung: p = 0.09
Heart - Left Ventricle: p = 0.12
H8_OTIMEDNASOtitis media, unspecifiedUK Biobank (UKBB)Neale Lab20182663609283Artery - Aorta: p = 0.00446
Uterus: p = 0.02
Vagina: p = 0.03
COPD_OPPORTUNIST_INFECTIONSCOPD related to chronic (opportunist) infectionsUK Biobank (UKBB)Neale Lab20184773607173Lung: p = 0.00211
Pancreas: p = 0.00608
Adipose - Subcutaneous: p = 0.06
D3_IMMUNEMECHANISMOTHEROther disorders involving the immune mechanism, not elsewhere classifiedUK Biobank (UKBB)Neale Lab20181723610223Liver: p = 0.002
Lung: p = 0.00222
Pancreas: p = 0.02
I9_LBBBLeft bundle-branch blockUK Biobank (UKBB)Neale Lab20181383610562Kidney - Cortex: p = 6.71E-4
Lung: p = 0.00653
Small Intestine - Terminal Ileum: p = 0.00985
M13_OTHCONN#Other systemic involvement of connective tissueUK Biobank (UKBB)Neale Lab20182343609603Liver: p = 0.005
Lung: p = 0.02
Spleen: p = 0.02
C_ENDOCRINENAUK Biobank (UKBB)Neale Lab20184293607653Adipose - Subcutaneous: p = 0.01
Lung: p = 0.02
Vagina: p = 0.04
G6_MONOOTHUNSOther and unsepcified mononeuropathies, also in other diseasesUK Biobank (UKBB)Neale Lab20181443610503Thyroid: p = 0.02
Muscle - Skeletal: p = 0.04
Vagina: p = 0.04
I9_AVBLOCKAV-blockUK Biobank (UKBB)Neale Lab20186093605853Testis: p = 0.02
Kidney - Cortex: p = 0.06
Skin - Sun Exposed (Lower leg): p = 0.06
C3_RECTOISIGMOID_JUNCTIONMalignant neoplasm of rectosigmoid junctionUK Biobank (UKBB)Neale Lab20183333608613Muscle - Skeletal: p = 0.00212
Ovary: p = 0.01
Breast - Mammary Tissue: p = 0.03
D3_PURPURA_AND3_OTHER_HAEMORRHAGICPurpura and other haemorrhagic conditionsUK Biobank (UKBB)Neale Lab20184603607342Muscle - Skeletal: p = 0.00853
Liver: p = 0.02
Whole Blood: p = 0.02
H7_EYEPOSTOPPostprocedural disorders of eye and adnexa, not elsewhere classifiedUK Biobank (UKBB)Neale Lab20181343610603Whole Blood: p = 0.02
Testis: p = 0.02
Stomach: p = 0.04
M13_OTHERJOINT#Other joint disordersUK Biobank (UKBB)Neale Lab2018273473338475Brain - Cerebellar Hemisphere: p = 0.00125
Brain - Cerebellum: p = 0.00619
Adrenal Gland: p = 0.00688
AB1_OTHER_VIRALOther viral diseasesUK Biobank (UKBB)Neale Lab201811803600143Esophagus - Mucosa: p = 1.51E-7
Vagina: p = 1.9E-5
Whole Blood: p = 0.0071
G6_CONCUSConcussionUK Biobank (UKBB)Neale Lab20181373610572Brain - Caudate (basal ganglia): p = 0.02
Brain - Nucleus accumbens (basal ganglia): p = 0.02
Brain - Putamen (basal ganglia): p = 0.05
I9_PERICARDPericarditisUK Biobank (UKBB)Neale Lab20181553610393Pituitary: p = 0.03
Whole Blood: p = 0.07
Skin - Not Sun Exposed (Suprapubic): p = 0.13
PRIM_KNEEARTHROSISPrimary gonarthrosis, bilateralUK Biobank (UKBB)Neale Lab20188493603452Artery - Aorta: p = 8.98E-4
Artery - Coronary: p = 0.00225
Artery - Tibial: p = 0.00946
H7_VISDISTNASOther and unspecified visual disturbancesUK Biobank (UKBB)Neale Lab20183013608933Lung: p = 0.02
Artery - Aorta: p = 0.07
Colon - Transverse: p = 0.09
H8_BPVBenign paroxysmal vertigoUK Biobank (UKBB)Neale Lab20181483610463Esophagus - Mucosa: p = 1.91E-4
Skin - Not Sun Exposed (Suprapubic): p = 2.57E-4
Skin - Sun Exposed (Lower leg): p = 2.57E-4
M13_ENTESOPATHYOTHOther enthesopathiesUK Biobank (UKBB)Neale Lab201810243601703Whole Blood: p = 0.00308
Pancreas: p = 0.02
Spleen: p = 0.03
H7_STRABOTHOther strabismusUK Biobank (UKBB)Neale Lab20186713605233Brain - Spinal cord (cervical c-1): p = 0.00288
Colon - Sigmoid: p = 0.00288
Adipose - Visceral (Omentum): p = 0.00678
I9_ARTOTHOther diseases of arteries and capillariesUK Biobank (UKBB)Neale Lab201810833601113Breast - Mammary Tissue: p = 0.00157
Lung: p = 0.00258
Adipose - Subcutaneous: p = 0.00414
IX_CIRCULATORYDiseases of the circulatory systemUK Biobank (UKBB)Neale Lab2018605043006905Heart - Atrial Appendage: p = 8.97E-5
Artery - Coronary: p = 4.1E-4
Artery - Tibial: p = 6.66E-4
VOCALCORDDYSVocal cord dysfunctionUK Biobank (UKBB)Neale Lab20184613607333Breast - Mammary Tissue: p = 0.00115
Nerve - Tibial: p = 0.03
Vagina: p = 0.03
C_NONFOLLICULAR_LYMPHOMANon-follicular lymphomaUK Biobank (UKBB)Neale Lab20187013604933Adipose - Visceral (Omentum): p = 0.03
Whole Blood: p = 0.03
Lung: p = 0.04
G6_SLEEPAPNOSleep apnoeaUK Biobank (UKBB)Neale Lab201822493589453Kidney - Cortex: p = 0.00128
Stomach: p = 0.00521
Adrenal Gland: p = 0.00592
I9_OTHOTHOther other unspecified disorders of the circulatory systemUK Biobank (UKBB)Neale Lab20181413610533Brain - Cortex: p = 0.01
Liver: p = 0.01
Kidney - Cortex: p = 0.03
K11_CHOLANGICholangitis (sclerosing)UK Biobank (UKBB)Neale Lab20182873609072Esophagus - Mucosa: p = 0.03
Artery - Coronary: p = 0.05
Skin - Sun Exposed (Lower leg): p = 0.07
L12_PYOGENGRANULPyogenic granulomaUK Biobank (UKBB)Neale Lab20182593609353Muscle - Skeletal: p = 0.02
Breast - Mammary Tissue: p = 0.04
Thyroid: p = 0.04
CHIRHEP_NASChirrosis of liver, NASUK Biobank (UKBB)Neale Lab20181843610103Uterus: p = 0.00426
Prostate: p = 0.00671
Colon - Sigmoid: p = 0.00843
M13_SOFTTISSUENASOther specified/unspecified soft tissue disordersUK Biobank (UKBB)Neale Lab201829303582643Pancreas: p = 0.02
Adipose - Visceral (Omentum): p = 0.02
Heart - Atrial Appendage: p = 0.02
GLOMER_NEPHRITISGlomerulonephritisUK Biobank (UKBB)Neale Lab20186293605652Brain - Substantia nigra: p = 0.00359
Brain - Hypothalamus: p = 0.01
Brain - Amygdala: p = 0.03
MENINGITISMeningitisUK Biobank (UKBB)Neale Lab20181343610602Lung: p = 4.54E-4
Brain - Cerebellar Hemisphere: p = 0.02
Brain - Cerebellum: p = 0.02
H7_LACRIGLANDOther disorders of lacrimal glandUK Biobank (UKBB)Neale Lab20181313610632Brain - Hypothalamus: p = 0.00307
Vagina: p = 0.00307
Brain - Anterior cingulate cortex (BA24): p = 0.02
M13_SOFTOVERUSESoft tissue disorders related to use, overuse and pressureUK Biobank (UKBB)Neale Lab201811323600623Artery - Aorta: p = 0.00124
Artery - Coronary: p = 0.00308
Artery - Tibial: p = 0.00308
H8_EXTDISNASOther specified disorders of external earUK Biobank (UKBB)Neale Lab20181103610842Breast - Mammary Tissue: p = 4.5E-4
Adipose - Subcutaneous: p = 0.02
Esophagus - Gastroesophageal Junction: p = 0.03
RHEU_ARTHRITIS_OTHOther arthritis (FG)UK Biobank (UKBB)Neale Lab201812123599822Kidney - Cortex: p = 0.0082
Esophagus - Mucosa: p = 0.02
Artery - Coronary: p = 0.05
L12_PIGMENTNASOther and unspecified disorders of pigmentationUK Biobank (UKBB)Neale Lab20181773610173Adipose - Subcutaneous: p = 0.00983
Adrenal Gland: p = 0.00983
Adipose - Visceral (Omentum): p = 0.01
D3_SCNDPOLYCYTHAEMIASecondary polycythaemiaUK Biobank (UKBB)Neale Lab20181593610353Ovary: p = 0.03
Minor Salivary Gland: p = 0.05
Uterus: p = 0.15
L12_PSORI_ARTHROArthropathic psoriasisUK Biobank (UKBB)Neale Lab20182403609544Lung: p = 4.3E-5
Spleen: p = 0.00183
Uterus: p = 0.02
M13_ENTESOPATHYLOWEnthesopathies of lower limb, excluding footUK Biobank (UKBB)Neale Lab20183023608923Esophagus - Mucosa: p = 7.34E-6
Vagina: p = 2.28E-5
Brain - Cortex: p = 6.09E-4
L12_NONIONRADISKINNASOther and unspecified skin changes due to chronic exposure to nonionizing radiationUK Biobank (UKBB)Neale Lab20181263610683Kidney - Cortex: p = 2.77E-4
Vagina: p = 0.00674
Prostate: p = 0.01
D3_ANAEMIA_IRONDEFIron deficiency anaemiaUK Biobank (UKBB)Neale Lab201837863574084Spleen: p = 3.43E-6
Lung: p = 5.18E-5
Colon - Sigmoid: p = 0.02
E4_HYTHYNASHypothyroidism,other/unspecifiedUK Biobank (UKBB)Neale Lab20181283610663Esophagus - Gastroesophageal Junction: p = 0.00151
Liver: p = 0.00151
Esophagus - Muscularis: p = 0.00395
I9_INTRACRANontraumatic intracranial haemmorrhageUK Biobank (UKBB)Neale Lab201812533599413Nerve - Tibial: p = 0.00507
Skin - Not Sun Exposed (Suprapubic): p = 0.01
Skin - Sun Exposed (Lower leg): p = 0.01
F5_ALCOHOLACAcute alcohol intoxicationUK Biobank (UKBB)Neale Lab20181313610633Heart - Atrial Appendage: p = 9.92E-4
Heart - Left Ventricle: p = 0.00733
Nerve - Tibial: p = 0.03
CHRONLARGECrohn's disease of large intestineUK Biobank (UKBB)Neale Lab20183363608583Artery - Tibial: p = 0.00874
Brain - Spinal cord (cervical c-1): p = 0.03
Spleen: p = 0.03
H7_STENOLACRIStenosis and insufficiency of lacrimal passagesUK Biobank (UKBB)Neale Lab20188223603723Stomach: p = 0.00559
Adipose - Visceral (Omentum): p = 0.02
Brain - Anterior cingulate cortex (BA24): p = 0.02
G6_DEMYELDemyelenating diseases of the central nervous systemUK Biobank (UKBB)Neale Lab20187883604065Spleen: p = 8.25E-7
Lung: p = 1.81E-6
Small Intestine - Terminal Ileum: p = 2.85E-4
NECROVASC_FG#Other necrotizing vasculopathies (FG)UK Biobank (UKBB)Neale Lab20181183610763Spleen: p = 0.00874
Brain - Cortex: p = 0.02
Skin - Sun Exposed (Lower leg): p = 0.03
INFLUENZAAll influenza (not pneumonia)UK Biobank (UKBB)Neale Lab20181473610473Lung: p = 0.00155
Artery - Aorta: p = 0.03
Artery - Coronary: p = 0.03
HYPOTHYROIDISMHypothyroidism (congenital or acquired)UK Biobank (UKBB)Neale Lab20181373610573Liver: p = 2.57E-4
Small Intestine - Terminal Ileum: p = 0.03
Colon - Sigmoid: p = 0.03
ASTHMA_MEDICATIO_COMORBMedication related adverse effectsUK Biobank (UKBB)Neale Lab2018200943411005Whole Blood: p = 1.63E-4
Spleen: p = 8.61E-4
Artery - Aorta: p = 0.00974
H7_OTHERCONJOther disorders of conjunctivaUK Biobank (UKBB)Neale Lab20184523607422Prostate: p = 0.02
Heart - Atrial Appendage: p = 0.02
Brain - Substantia nigra: p = 0.05
E4_OBESITYObesityUK Biobank (UKBB)Neale Lab20184483607463Colon - Sigmoid: p = 0.01
Skin - Not Sun Exposed (Suprapubic): p = 0.02
Heart - Atrial Appendage: p = 0.04
M13_POLYARTHROPATHIES#PolyarthropathiesUK Biobank (UKBB)Neale Lab201832753579195Spleen: p = 3.94E-8
Lung: p = 4.0E-7
Small Intestine - Terminal Ileum: p = 0.00689
D3_HYPERGAMMAGLONASHypergammalglobulinemia, unspecifiedUK Biobank (UKBB)Neale Lab20181423610522Pancreas: p = 5.89E-4
Small Intestine - Terminal Ileum: p = 0.02
Whole Blood: p = 0.03
M13_DEQUERVAINRadial styloid tenosynovitis [de Quervain]UK Biobank (UKBB)Neale Lab20182423609523Thyroid: p = 0.01
Brain - Hippocampus: p = 0.02
Pituitary: p = 0.03
C_EYE_BRAIN_NEURONAUK Biobank (UKBB)Neale Lab20185173606773Heart - Atrial Appendage: p = 0.00352
Small Intestine - Terminal Ileum: p = 0.00706
Lung: p = 0.0071
G6_MYONEUDiseases of the myoneural junction and muscleUK Biobank (UKBB)Neale Lab20182343609603Vagina: p = 0.00519
Thyroid: p = 0.00804
Muscle - Skeletal: p = 0.04
H7_ECTROPIONEctropion of eyelidUK Biobank (UKBB)Neale Lab20183173608773Uterus: p = 2.77E-6
Artery - Coronary: p = 1.04E-5
Artery - Aorta: p = 6.62E-5
I9_HYPTENSHypertensionUK Biobank (UKBB)Neale Lab201812373599573Esophagus - Gastroesophageal Junction: p = 0.00232
Small Intestine - Terminal Ileum: p = 0.0054
Esophagus - Muscularis: p = 0.01
IBD_BACT_INTEST_INFECTIONSBacterial intestinal infections, IBD co-morbiditiesUK Biobank (UKBB)Neale Lab20189243602703Skin - Sun Exposed (Lower leg): p = 0.00744
Heart - Left Ventricle: p = 0.01
Muscle - Skeletal: p = 0.02
I9_VASCINTVascular diseases of the intestineUK Biobank (UKBB)Neale Lab20182723609223Minor Salivary Gland: p = 3.24E-4
Skin - Not Sun Exposed (Suprapubic): p = 0.0062
Skin - Sun Exposed (Lower leg): p = 0.05
C3_LIVER_INTRAHEPATIC_BILE_DUCTSMalignant neoplasm of liver and intrahepatic bile ductsUK Biobank (UKBB)Neale Lab20182043609903Nerve - Tibial: p = 3.45E-5
Adrenal Gland: p = 0.00153
Ovary: p = 0.009
IV_ENDOCRIN_NUTRITEndocrine, nutritional and metabolic diseasesUK Biobank (UKBB)Neale Lab201872183539765Lung: p = 1.61E-5
Uterus: p = 5.59E-5
Spleen: p = 5.45E-4
F5_SCHIZOSchizophrenia, schizotypal and delusional disordersUK Biobank (UKBB)Neale Lab20184613607333Artery - Aorta: p = 0.00206
Artery - Coronary: p = 0.00206
Uterus: p = 0.00804
G6_ULLNLELesion of ulnar nerveUK Biobank (UKBB)Neale Lab20188213603733Colon - Sigmoid: p = 0.00339
Pancreas: p = 0.02
Brain - Substantia nigra: p = 0.03
I9_AORTANEURAortic aneurysmUK Biobank (UKBB)Neale Lab20185893606053Artery - Coronary: p = 0.00254
Artery - Tibial: p = 0.00254
Minor Salivary Gland: p = 0.00952
L12_FOREIGNBODYGRANULOMAForeign body granuloma of skin and subcutaneous tissueUK Biobank (UKBB)Neale Lab20181043610903Lung: p = 0.00537
Adipose - Visceral (Omentum): p = 0.03
Nerve - Tibial: p = 0.03
K11_APPENDIXDiseases of appendixUK Biobank (UKBB)Neale Lab201829533582413Colon - Sigmoid: p = 1.55E-5
Prostate: p = 1.02E-4
Vagina: p = 1.02E-4
ENDOMETRIOSIS_UTERUSEndometriosis of uterusUK Biobank (UKBB)Neale Lab20185053606893Stomach: p = 0.00199
Artery - Aorta: p = 0.00421
Artery - Tibial: p = 0.00421
C3_SMALL_INTESTINEMalignant neoplasm of small intestineUK Biobank (UKBB)Neale Lab20181413610532Brain - Cerebellum: p = 1.07E-5
Brain - Cerebellar Hemisphere: p = 3.62E-5
Heart - Left Ventricle: p = 0.00901
M13_ALGONEUROAlogoneurodystrophyUK Biobank (UKBB)Neale Lab20181233610713Uterus: p = 0.00983
Skin - Sun Exposed (Lower leg): p = 0.02
Brain - Hypothalamus: p = 0.02
IPFIdiopathic pulmonary fibrosis (attempt to specificity)UK Biobank (UKBB)Neale Lab20183383608563Esophagus - Gastroesophageal Junction: p = 0.00164
Kidney - Cortex: p = 0.02
Brain - Cortex: p = 0.02
L12_HYPETROPHICSCARHypertrophic scarUK Biobank (UKBB)Neale Lab20181533610413Nerve - Tibial: p = 0.00761
Brain - Cerebellar Hemisphere: p = 0.00874
Brain - Cerebellum: p = 0.00874
M13_PREPATELLARBURSITISPrepatellar bursitisUK Biobank (UKBB)Neale Lab20182223609723Esophagus - Gastroesophageal Junction: p = 0.00657
Esophagus - Muscularis: p = 0.01
Colon - Sigmoid: p = 0.02
K11_OTHGASTROther gastritis (incl. Duodenitis)UK Biobank (UKBB)Neale Lab2018105183506763Heart - Atrial Appendage: p = 0.01
Heart - Left Ventricle: p = 0.02
Nerve - Tibial: p = 0.02
J10_ASTHMA_MAINAsthmaUK Biobank (UKBB)Neale Lab201819933592015Lung: p = 9.81E-7
Spleen: p = 8.56E-5
Whole Blood: p = 0.00385
H7_MACULADEGENDegeneration of macula and posterior poleUK Biobank (UKBB)Neale Lab201810133601813Esophagus - Mucosa: p = 0.01
Artery - Aorta: p = 0.04
Small Intestine - Terminal Ileum: p = 0.07
M13_DORSOPATHYOTHOther dorsopathies, not elsewhere classifiedUK Biobank (UKBB)Neale Lab20183603608343Heart - Left Ventricle: p = 0.01
Kidney - Cortex: p = 0.02
Heart - Atrial Appendage: p = 0.03
C_CORPUS_UTERIMalignant neoplasm of corpus uteriUK Biobank (UKBB)Neale Lab201812223599723Whole Blood: p = 0.005
Pituitary: p = 0.02
Spleen: p = 0.02
C_PRIMARY_LYMPHOID_HEMATOPOIETICNAUK Biobank (UKBB)Neale Lab201830303581644Spleen: p = 3.72E-5
Whole Blood: p = 0.00255
Lung: p = 0.00467
L12_GRANULOMASKINNASOther and unspecified granulomatous disorders of skin and subcutaneous tissueUK Biobank (UKBB)Neale Lab20181963609982Adipose - Subcutaneous: p = 5.45E-4
Skin - Not Sun Exposed (Suprapubic): p = 0.03
Skin - Sun Exposed (Lower leg): p = 0.03
C_TESTISMalignant neoplasm of testisUK Biobank (UKBB)Neale Lab20184323607624Esophagus - Gastroesophageal Junction: p = 0.03
Artery - Tibial: p = 0.05
Pancreas: p = 0.06
M13_MUSCULOSKELEOTHOther disorders of the musculoskeletal system and connective tissueUK Biobank (UKBB)Neale Lab20184993606953Minor Salivary Gland: p = 0.04
Thyroid: p = 0.04
Whole Blood: p = 0.04
STILL_ADULTAdult-onset Still diseaseUK Biobank (UKBB)Neale Lab201814863597085Spleen: p = 1.68E-9
Lung: p = 5.27E-7
Small Intestine - Terminal Ileum: p = 5.29E-5
M13_SPONDYLOPATHY#SpondylopathiesUK Biobank (UKBB)Neale Lab201843933568013Pituitary: p = 0.00246
Artery - Coronary: p = 0.00405
Heart - Atrial Appendage: p = 0.00571
C_LYMPHOID_LEUKAEMIALymphoid leukaemiaUK Biobank (UKBB)Neale Lab20185183606763Spleen: p = 1.16E-4
Lung: p = 4.5E-4
Small Intestine - Terminal Ileum: p = 0.03
MEMLOSSMemory lossUK Biobank (UKBB)Neale Lab20182023609923Kidney - Cortex: p = 0.00968
Minor Salivary Gland: p = 0.02
Nerve - Tibial: p = 0.04
C3_OVARYMalignant neoplasm of ovaryUK Biobank (UKBB)Neale Lab20188443603502Kidney - Cortex: p = 3.8E-4
Pancreas: p = 0.04
Lung: p = 0.06
F5_ALLANXIOUSAll anxiety disordersUK Biobank (UKBB)Neale Lab20185323606623Adrenal Gland: p = 0.00196
Minor Salivary Gland: p = 0.00511
Uterus: p = 0.01
H8_CONSENHEARINGLOSSConductive and sensorineural hearing lossUK Biobank (UKBB)Neale Lab20182993608952Whole Blood: p = 0.0025
Testis: p = 0.07
Brain - Amygdala: p = 0.08
AB1_INTESTINAL_INFECTIONSIntestinal infectious diseasesUK Biobank (UKBB)Neale Lab201843043568903Ovary: p = 0.00222
Breast - Mammary Tissue: p = 0.00561
Uterus: p = 0.00813
XIII_MUSCULOSKELETDiseases of the musculoskeletal system and connective tissueUK Biobank (UKBB)Neale Lab2018770992840954Brain - Nucleus accumbens (basal ganglia): p = 3.98E-4
Brain - Amygdala: p = 0.00225
Brain - Caudate (basal ganglia): p = 0.00427
C_NONHODGKIN_NASOther and unspecified types of non-Hodgkin lymphomaUK Biobank (UKBB)Neale Lab20183933608015Lung: p = 0.00122
Uterus: p = 0.00414
Skin - Not Sun Exposed (Suprapubic): p = 0.02
C_ANUS_ANALCANALMalignant neoplasm of anus and anal canalUK Biobank (UKBB)Neale Lab20181273610675Lung: p = 4.27E-6
Skin - Sun Exposed (Lower leg): p = 1.98E-4
Whole Blood: p = 5.8E-4
H7_PTERYGIUMPterygiumUK Biobank (UKBB)Neale Lab20181243610703Lung: p = 0.03
Heart - Left Ventricle: p = 0.05
Artery - Tibial: p = 0.05
SCND_OTH_COXARTHROSISOther secondary coxarthrosisUK Biobank (UKBB)Neale Lab20181083610863Heart - Atrial Appendage: p = 0.00106
Heart - Left Ventricle: p = 0.01
Muscle - Skeletal: p = 0.02
I9_ANEURYSMCerebral aneurysm, nonrupturedUK Biobank (UKBB)Neale Lab20182253609693Liver: p = 0.03
Brain - Spinal cord (cervical c-1): p = 0.05
Thyroid: p = 0.06
I9_HEARTFAILHeart failure,strictUK Biobank (UKBB)Neale Lab201814053597893Pancreas: p = 7.21E-4
Prostate: p = 0.00285
Stomach: p = 0.00492
C_SMALL_INTESTINEMalignant neoplasm of small intestineUK Biobank (UKBB)Neale Lab20181413610532Brain - Cerebellum: p = 1.07E-5
Brain - Cerebellar Hemisphere: p = 3.62E-5
Heart - Left Ventricle: p = 0.00901
COPD_EXCLCOPD differential diagnosisUK Biobank (UKBB)Neale Lab2018267103344844Whole Blood: p = 6.56E-4
Lung: p = 0.00192
Colon - Transverse: p = 0.00601
G6_DEGENOTHOther and unspecified degenerative diseases of nervous systemUK Biobank (UKBB)Neale Lab20181063610883Pituitary: p = 0.00447
Brain - Frontal Cortex (BA9): p = 0.02
Brain - Cortex: p = 0.04
C_EYE_ADNEXAMalignant neoplasm of eye and adnexaUK Biobank (UKBB)Neale Lab20181153610792Adrenal Gland: p = 0.00209
Brain - Cortex: p = 0.00524
Brain - Amygdala: p = 0.00835
H7_BCKRNDRETINOPATBackground retinopathy and retinal vascular changesUK Biobank (UKBB)Neale Lab20181083610862Kidney - Cortex: p = 0.0012
Vagina: p = 0.0012
Uterus: p = 0.00155
H7_PARASTRABParalytic strabismusUK Biobank (UKBB)Neale Lab20181403610543Uterus: p = 4.76E-5
Kidney - Cortex: p = 4.34E-4
Heart - Atrial Appendage: p = 0.00321
I9_ARTEMBTHRLOWArterial embolism and thrombosis of lower extremity arteryUK Biobank (UKBB)Neale Lab20183623608323Esophagus - Gastroesophageal Junction: p = 0.00719
Esophagus - Muscularis: p = 0.00719
Testis: p = 0.02
C_CERVIX_UTERIMalignant neoplasm of cervix uteriUK Biobank (UKBB)Neale Lab20183683608263Kidney - Cortex: p = 0.03
Liver: p = 0.03
Muscle - Skeletal: p = 0.03
H7_EYEADNEXOTHOther specified and unspecified disorders of eye and adnexaUK Biobank (UKBB)Neale Lab20181303610642Spleen: p = 0.05
Esophagus - Mucosa: p = 0.05
Colon - Transverse: p = 0.08
I9_OTHILLHEARTOther or ill-defined heart diseasesUK Biobank (UKBB)Neale Lab20183353608593Artery - Aorta: p = 9.62E-4
Artery - Coronary: p = 0.02
Prostate: p = 0.02
H7_CHALAZIONChalazionUK Biobank (UKBB)Neale Lab201814183597764Whole Blood: p = 1.18E-4
Lung: p = 1.28E-4
Uterus: p = 6.68E-4
PNEUMONIAPneumonias (Asthma/COPD co-morbidities)UK Biobank (UKBB)Neale Lab201859003552943Lung: p = 0.00879
Breast - Mammary Tissue: p = 0.01
Minor Salivary Gland: p = 0.02
M13_RADICULOPATHYRadiculopathyUK Biobank (UKBB)Neale Lab20185323606623Brain - Cortex: p = 4.45E-4
Brain - Nucleus accumbens (basal ganglia): p = 7.56E-4
Brain - Anterior cingulate cortex (BA24): p = 0.00331
L12_URTICA_NASOther and unspecified urticariaUK Biobank (UKBB)Neale Lab20181063610883Brain - Spinal cord (cervical c-1): p = 0.02
Nerve - Tibial: p = 0.07
Lung: p = 0.09
C3_RECTUMMalignant neoplasm of rectumUK Biobank (UKBB)Neale Lab201811703600243Whole Blood: p = 0.00497
Adrenal Gland: p = 0.01
Heart - Atrial Appendage: p = 0.02
M13_THORACISPINEPAINPain in thoracic spineUK Biobank (UKBB)Neale Lab20181643610302Whole Blood: p = 0.02
Colon - Transverse: p = 0.06
Thyroid: p = 0.07
C3_PANCREASMalignant neoplasm of pancreasUK Biobank (UKBB)Neale Lab20184403607542Lung: p = 4.19E-4
Ovary: p = 0.0021
Adrenal Gland: p = 0.00331
C3_THYROID_GLANDMalignant neoplasm of thyroid glandUK Biobank (UKBB)Neale Lab20183943608003Colon - Transverse: p = 0.01
Vagina: p = 0.02
Minor Salivary Gland: p = 0.04
C3_SECONDARY_RESPIRATORY_DIGESTIVESecondary malignant neoplasm of respiratory and digestive organsUK Biobank (UKBB)Neale Lab20181093610853Stomach: p = 0.02
Heart - Atrial Appendage: p = 0.12
Nerve - Tibial: p = 0.12
L12_HYPERTROPHICNASOther and unspecified hypertrophic disorders of skinUK Biobank (UKBB)Neale Lab20184783607163Liver: p = 0.00874
Stomach: p = 0.05
Prostate: p = 0.05
V_MENTAL_BEHAVMental and behavioural disordersUK Biobank (UKBB)Neale Lab201843023568923Brain - Anterior cingulate cortex (BA24): p = 0.04
Brain - Spinal cord (cervical c-1): p = 0.04
Brain - Hypothalamus: p = 0.04
M13_HALLUXRIGIDUSHallux rigidusUK Biobank (UKBB)Neale Lab201811303600643Ovary: p = 5.49E-4
Adrenal Gland: p = 0.01
Esophagus - Muscularis: p = 0.02
M13_DEFORMDORSO#Deforming dorsopathiesUK Biobank (UKBB)Neale Lab20189093602853Pituitary: p = 0.00139
Thyroid: p = 0.00163
Colon - Sigmoid: p = 0.04
ULCERNASUlcerative colitis, NASUK Biobank (UKBB)Neale Lab201819033592915Lung: p = 2.09E-6
Spleen: p = 4.27E-6
Whole Blood: p = 0.00239
I9_CEREBDOTHOther specified cerebrovascular diseases, other cerebrovascular disorders in diseases classified elsewhereUK Biobank (UKBB)Neale Lab20181773610172Colon - Transverse: p = 0.03
Whole Blood: p = 0.03
Esophagus - Gastroesophageal Junction: p = 0.04
H7_EYELIDNASOther specified and unspecified disorders of eyelidUK Biobank (UKBB)Neale Lab201821863590082Ovary: p = 0.02
Lung: p = 0.03
Adipose - Visceral (Omentum): p = 0.04
H8_OTALGIAOtalgiaUK Biobank (UKBB)Neale Lab20181353610593Muscle - Skeletal: p = 0.00411
Spleen: p = 0.00592
Small Intestine - Terminal Ileum: p = 0.03
D3_THROMBOCYTOPENIANASThrombocytopenia, unspecifiedUK Biobank (UKBB)Neale Lab20182303609643Heart - Atrial Appendage: p = 0.01
Muscle - Skeletal: p = 0.02
Brain - Cerebellar Hemisphere: p = 0.04
F5_DEPRESSIODepressionUK Biobank (UKBB)Neale Lab201811453600493Brain - Anterior cingulate cortex (BA24): p = 2.4E-4
Brain - Frontal Cortex (BA9): p = 0.00191
Brain - Hippocampus: p = 0.00191
M13_LATERALEPICONDLateral epicondylitisUK Biobank (UKBB)Neale Lab20185253606693Brain - Caudate (basal ganglia): p = 0.01
Whole Blood: p = 0.01
Brain - Amygdala: p = 0.03
M13_SHOULDERShoulder lesionsUK Biobank (UKBB)Neale Lab201872433539513Prostate: p = 0.01
Muscle - Skeletal: p = 0.02
Skin - Not Sun Exposed (Suprapubic): p = 0.02
PRIM_COXARTHROSISPrimary coxarthrosis, bilateralUK Biobank (UKBB)Neale Lab20185793606153Skin - Not Sun Exposed (Suprapubic): p = 0.03
Skin - Sun Exposed (Lower leg): p = 0.03
Adrenal Gland: p = 0.04
AMN2Transient global amnesiaUK Biobank (UKBB)Neale Lab20182833609113Pancreas: p = 1.1E-4
Brain - Substantia nigra: p = 3.38E-4
Stomach: p = 0.00265
ULCEROTHOther ulcerative colitisUK Biobank (UKBB)Neale Lab20181593610353Pancreas: p = 6.88E-4
Esophagus - Gastroesophageal Junction: p = 0.00874
Esophagus - Muscularis: p = 0.00874
CAMPYLOENTERITISCampylobacter enteritisUK Biobank (UKBB)Neale Lab20182893609053Lung: p = 0.00119
Thyroid: p = 0.00287
Minor Salivary Gland: p = 0.00456
DM_HYPOGLYCDiabetic hypoglycemiaUK Biobank (UKBB)Neale Lab20183853608094Spleen: p = 2.34E-7
Lung: p = 9.36E-6
Pituitary: p = 0.00149
G6_EPIPAROXEpisodal and paroxysmal disordersUK Biobank (UKBB)Neale Lab201854183557763Colon - Transverse: p = 0.01
Artery - Coronary: p = 0.02
Brain - Anterior cingulate cortex (BA24): p = 0.04
M13_HALLUXVALGUSHallux valgus (acquired)UK Biobank (UKBB)Neale Lab201853703558244Uterus: p = 0.00294
Esophagus - Gastroesophageal Junction: p = 0.0086
Spleen: p = 0.01
L12_HIDRADENITISSUPHidradenitis suppurativaUK Biobank (UKBB)Neale Lab20181353610592Spleen: p = 0.002
Adipose - Subcutaneous: p = 0.00804
Colon - Transverse: p = 0.00804
I9_STR_EXHIschaemic Stroke, excluding all haemorrhagesUK Biobank (UKBB)Neale Lab201833143578803Skin - Sun Exposed (Lower leg): p = 0.00707
Vagina: p = 0.01
Muscle - Skeletal: p = 0.02
C_DIGESTIVE_ORGANSNAUK Biobank (UKBB)Neale Lab201856903555043Skin - Sun Exposed (Lower leg): p = 0.00412
Skin - Not Sun Exposed (Suprapubic): p = 0.00618
Adipose - Subcutaneous: p = 0.02
C3_STOMACHMalignant neoplasm of stomachUK Biobank (UKBB)Neale Lab20183513608433Adrenal Gland: p = 0.01
Lung: p = 0.02
Prostate: p = 0.02
I9_K_CARDIACDeath due to cardiac causesUK Biobank (UKBB)Neale Lab201815973595973Whole Blood: p = 0.02
Ovary: p = 0.02
Breast - Mammary Tissue: p = 0.04
G6_DIFBRAININJDiffuse brain injuryUK Biobank (UKBB)Neale Lab20181153610794Skin - Sun Exposed (Lower leg): p = 8.22E-5
Esophagus - Mucosa: p = 0.00324
Skin - Not Sun Exposed (Suprapubic): p = 0.00324
I9_HYPTENSPREGHypertension complicating pregnancy, childbirth, and the puerperiumUK Biobank (UKBB)Neale Lab20187433604513Prostate: p = 0.00333
Vagina: p = 0.00333
Esophagus - Mucosa: p = 0.03
M13_SCIATICASiatica+with lumbagoUK Biobank (UKBB)Neale Lab201811533600413Spleen: p = 0.02
Thyroid: p = 0.03
Nerve - Tibial: p = 0.06
H7_XANTHELASMAXanthelasma of eyelidUK Biobank (UKBB)Neale Lab20181533610413Pancreas: p = 7.72E-4
Liver: p = 0.01
Nerve - Tibial: p = 0.02
C_MESTOTHEL_SOFTTISSUENAUK Biobank (UKBB)Neale Lab20185143606803Stomach: p = 0.01
Brain - Cerebellum: p = 0.02
Kidney - Cortex: p = 0.02
G6_SAHTRAUTraumatic subarachnoid haemorrhageUK Biobank (UKBB)Neale Lab20181243610703Nerve - Tibial: p = 0.00196
Heart - Left Ventricle: p = 0.00862
Adipose - Visceral (Omentum): p = 0.02
C_URINARY_TRACTNAUK Biobank (UKBB)Neale Lab201818413593533Brain - Cerebellar Hemisphere: p = 0.02
Brain - Spinal cord (cervical c-1): p = 0.02
Colon - Transverse: p = 0.02
G6_PLANTARLesion of plantar nerveUK Biobank (UKBB)Neale Lab20189793602153Spleen: p = 7.4E-4
Prostate: p = 0.02
Small Intestine - Terminal Ileum: p = 0.05
PULM_MEDICATIO_COMORBMedication related adverse effects (Asthma/COPD)UK Biobank (UKBB)Neale Lab2018217063394885Spleen: p = 7.01E-4
Esophagus - Gastroesophageal Junction: p = 0.00437
Artery - Coronary: p = 0.00743
C_LYMPHOMALymphomasUK Biobank (UKBB)Neale Lab201817523594425Lung: p = 8.8E-5
Spleen: p = 1.29E-4
Small Intestine - Terminal Ileum: p = 0.00157
C_COLONMalignant neoplasm of colonUK Biobank (UKBB)Neale Lab201824373587573Thyroid: p = 1.24E-4
Whole Blood: p = 0.00292
Heart - Atrial Appendage: p = 0.02
KRA_PSY_ANXIETYAnxiety disordersUK Biobank (UKBB)Neale Lab201810923601023Skin - Not Sun Exposed (Suprapubic): p = 0.01
Skin - Sun Exposed (Lower leg): p = 0.01
Brain - Cortex: p = 0.02
M13_GIANTCELLGiant cell arteritisUK Biobank (UKBB)Neale Lab20182313609633Lung: p = 6.29E-5
Brain - Caudate (basal ganglia): p = 0.00477
Brain - Cortex: p = 0.00477
E4_DM1NOCOMPType 1 diabetes without complicationsUK Biobank (UKBB)Neale Lab20182473609475Spleen: p = 1.3E-7
Lung: p = 1.8E-6
Skin - Not Sun Exposed (Suprapubic): p = 3.82E-4
AB1_OTHER_BACTERIALOther bacterial diseasesUK Biobank (UKBB)Neale Lab201819623592323Whole Blood: p = 5.86E-4
Ovary: p = 0.01
Nerve - Tibial: p = 0.03
C_PANCREASMalignant neoplasm of pancreasUK Biobank (UKBB)Neale Lab20184403607542Lung: p = 4.19E-4
Ovary: p = 0.0021
Adrenal Gland: p = 0.00331
LUNG_CANCERLung cancer and mesotheliomaUK Biobank (UKBB)Neale Lab201820073591873Colon - Transverse: p = 0.00321
Brain - Cortex: p = 0.04
Brain - Frontal Cortex (BA9): p = 0.06
C_MULTIPLE_MYELOMA_PLASMA_CELLMultiple myeloma and malignant plasma cell neoplasmsUK Biobank (UKBB)Neale Lab20184283607663Colon - Transverse: p = 0.00569
Brain - Spinal cord (cervical c-1): p = 0.00696
Nerve - Tibial: p = 0.04
G6_POLYNEUPolyneuropathies and other disorders of the peripheral nervous systemUK Biobank (UKBB)Neale Lab20185603606343Skin - Sun Exposed (Lower leg): p = 0.00239
Skin - Not Sun Exposed (Suprapubic): p = 0.00935
Vagina: p = 0.04
G6_CARPTUCarpal tunnel syndromeUK Biobank (UKBB)Neale Lab201879733532215Lung: p = 1.06E-4
Artery - Aorta: p = 3.07E-4
Artery - Tibial: p = 0.00592
G6_POLYOTHUNSOther and unspecified polyneuropathies, also in other diseasesUK Biobank (UKBB)Neale Lab20183793608153Testis: p = 6.32E-4
Vagina: p = 0.02
Heart - Atrial Appendage: p = 0.03
C_STOMACHMalignant neoplasm of stomachUK Biobank (UKBB)Neale Lab20183513608433Adrenal Gland: p = 0.01
Lung: p = 0.02
Prostate: p = 0.02
M13_MENISCUSDERANGEMENTSMeniscus derangementUK Biobank (UKBB)Neale Lab2018108313503634Adipose - Subcutaneous: p = 0.02
Nerve - Tibial: p = 0.02
Ovary: p = 0.03
C_MESOTHELIOMAMesotheliomaUK Biobank (UKBB)Neale Lab20181653610293Artery - Tibial: p = 1.62E-5
Artery - Coronary: p = 0.00125
Artery - Aorta: p = 0.0032
M13_ROTATORCUFFRotator cuff syndromeUK Biobank (UKBB)Neale Lab201822853589093Heart - Left Ventricle: p = 0.02
Pancreas: p = 0.04
Skin - Not Sun Exposed (Suprapubic): p = 0.04
M13_GANGLIONGanglionUK Biobank (UKBB)Neale Lab201822393589553Kidney - Cortex: p = 0.00232
Colon - Transverse: p = 0.02
Whole Blood: p = 0.04
BRONCHITISBronchitisUK Biobank (UKBB)Neale Lab201842833569113Skin - Sun Exposed (Lower leg): p = 0.00594
Skin - Not Sun Exposed (Suprapubic): p = 0.02
Brain - Anterior cingulate cortex (BA24): p = 0.04
XI_DIGESTIVEDiseases of the digestive systemUK Biobank (UKBB)Neale Lab20181158932453014Brain - Anterior cingulate cortex (BA24): p = 0.00303
Brain - Cerebellar Hemisphere: p = 0.00303
Brain - Cerebellum: p = 0.0042
K11_ACHALAchalasia of cardiaUK Biobank (UKBB)Neale Lab20181193610753Artery - Coronary: p = 0.03
Breast - Mammary Tissue: p = 0.03
Artery - Aorta: p = 0.03
G6_NEUATRSystemic atrophies primarly affecting the central nervous systemUK Biobank (UKBB)Neale Lab20182123609822Testis: p = 0.01
Skin - Not Sun Exposed (Suprapubic): p = 0.01
Skin - Sun Exposed (Lower leg): p = 0.01
ASTHMA_OPPORTUNIST_INFECTIONSNAUK Biobank (UKBB)Neale Lab20185093606853Lung: p = 0.02
Adipose - Subcutaneous: p = 0.03
Esophagus - Gastroesophageal Junction: p = 0.03
M13_ARTHROSIS#ArthrosisUK Biobank (UKBB)Neale Lab2018249773362174Artery - Tibial: p = 0.00553
Artery - Aorta: p = 0.01
Artery - Coronary: p = 0.01
H8_LABYRINTHITISLabyrinthitisUK Biobank (UKBB)Neale Lab20185173606773Brain - Amygdala: p = 3.26E-4
Brain - Cerebellar Hemisphere: p = 0.00274
Brain - Hypothalamus: p = 0.00274
D3_COAGOTHEROther coagulation defectsUK Biobank (UKBB)Neale Lab20181143610802Testis: p = 0.00228
Liver: p = 0.01
Artery - Tibial: p = 0.03
AB1_INFECTIONSCertain infectious and parasitic diseasesUK Biobank (UKBB)Neale Lab201875303536643Uterus: p = 0.00548
Brain - Amygdala: p = 0.00835
Artery - Coronary: p = 0.01
NAFLDNonalcoholic fatty liver diseaseUK Biobank (UKBB)Neale Lab20182753609193Liver: p = 0.00421
Skin - Not Sun Exposed (Suprapubic): p = 0.01
Skin - Sun Exposed (Lower leg): p = 0.01
I9_PULMOTHHDOther pulmonary heart/vessel diseaseUK Biobank (UKBB)Neale Lab20181673610273Esophagus - Gastroesophageal Junction: p = 0.00221
Esophagus - Muscularis: p = 0.00221
Artery - Coronary: p = 0.00534
ASTHMA_HOSPITAL1Asthma, hospital admissions 1UK Biobank (UKBB)Neale Lab201819863592085Lung: p = 8.14E-7
Spleen: p = 3.91E-5
Whole Blood: p = 0.00115
L12_EPIDERMALTHICKOTHOther epidermal thickeningUK Biobank (UKBB)Neale Lab20184283607663Brain - Cerebellar Hemisphere: p = 0.03
Adipose - Visceral (Omentum): p = 0.05
Spleen: p = 0.05
FIBRO_COMORBFibromyalgia related co-morbiditiesUK Biobank (UKBB)Neale Lab201823053588893Whole Blood: p = 5.62E-4
Lung: p = 0.00264
Adrenal Gland: p = 0.00907
H8_MYRINGNASOther specified/unspecified disorders of tympanic membraneUK Biobank (UKBB)Neale Lab20181623610323Pituitary: p = 8.58E-4
Liver: p = 0.00599
Adipose - Visceral (Omentum): p = 0.01
H7_POSTOPEYENASOher and unspecified postprocedural disorders of eye and adnexaUK Biobank (UKBB)Neale Lab20181253610693Testis: p = 0.00606
Whole Blood: p = 0.01
Colon - Transverse: p = 0.03
L12_ERYTHEMATOUSOTHOther erythematous conditionsUK Biobank (UKBB)Neale Lab20181183610763Breast - Mammary Tissue: p = 0.00623
Prostate: p = 0.00917
Adipose - Visceral (Omentum): p = 0.01
C3_UNCERTAIN_SECONDARYSecondary uncertain malignant neoplasmUK Biobank (UKBB)Neale Lab20184233607713Vagina: p = 0.00222
Brain - Hypothalamus: p = 0.00974
Colon - Sigmoid: p = 0.00974
M13_PLANTARFASCPlantar fascial fibromatosisUK Biobank (UKBB)Neale Lab20182003609943Skin - Sun Exposed (Lower leg): p = 0.00222
Skin - Not Sun Exposed (Suprapubic): p = 0.00362
Brain - Nucleus accumbens (basal ganglia): p = 0.00874
C_TONSILMalignant neoplasm of tonsilUK Biobank (UKBB)Neale Lab20181753610193Lung: p = 0.00259
Spleen: p = 0.00599
Whole Blood: p = 0.00727
I9_RHEUVALVRheumatic valve diseasesUK Biobank (UKBB)Neale Lab20184273607673Heart - Atrial Appendage: p = 0.00855
Adipose - Visceral (Omentum): p = 0.02
Kidney - Cortex: p = 0.02
K11_OTHDISOESOther diseases of oesophagusUK Biobank (UKBB)Neale Lab201811853600093Brain - Substantia nigra: p = 0.02
Breast - Mammary Tissue: p = 0.03
Skin - Not Sun Exposed (Suprapubic): p = 0.03
I9_HYPTENSHRHypertensive heart and/or renal diseaseUK Biobank (UKBB)Neale Lab20183763608183Kidney - Cortex: p = 4.61E-4
Colon - Transverse: p = 0.0032
Colon - Sigmoid: p = 0.00766
M13_PATELLAOTHOther disorders of patellaUK Biobank (UKBB)Neale Lab20183753608193Brain - Anterior cingulate cortex (BA24): p = 0.00488
Brain - Frontal Cortex (BA9): p = 0.00488
Brain - Caudate (basal ganglia): p = 0.00495
L12_SKINSUBCUTISNASOther and unspecified disorders of skin and subcutaneous tissueUK Biobank (UKBB)Neale Lab201838013573933Colon - Sigmoid: p = 2.26E-4
Artery - Tibial: p = 0.00179
Esophagus - Gastroesophageal Junction: p = 0.00675
G6_BELLPABell's palsyUK Biobank (UKBB)Neale Lab20183383608562Colon - Sigmoid: p = 0.00328
Artery - Coronary: p = 0.02
Testis: p = 0.03
H7_DIVERGSTRABDivergent concomitant strabismusUK Biobank (UKBB)Neale Lab20182763609182Uterus: p = 4.41E-4
Artery - Aorta: p = 0.00124
Liver: p = 0.00584
M13_PATHODISLOCATIOPathological/recurrent dislocation and subluxation of joint, not elsewhere classifiedUK Biobank (UKBB)Neale Lab20182233609712Whole Blood: p = 4.41E-4
Uterus: p = 0.00496
Vagina: p = 0.00763
M13_METATARSALGIAMetatarsalgiaUK Biobank (UKBB)Neale Lab20181763610183Heart - Left Ventricle: p = 0.01
Pancreas: p = 0.02
Artery - Tibial: p = 0.02
E4_DM1Type 1 diabetesUK Biobank (UKBB)Neale Lab20185833606115Spleen: p = 2.94E-9
Lung: p = 4.99E-5
Whole Blood: p = 4.41E-4
I9_UAPUnstable angina pectorisUK Biobank (UKBB)Neale Lab201834393577553Artery - Coronary: p = 3.57E-4
Artery - Aorta: p = 8.05E-4
Heart - Atrial Appendage: p = 0.00174
G6_NEURODEGOther degenerative diseases of the nervous systemUK Biobank (UKBB)Neale Lab20182423609524Small Intestine - Terminal Ileum: p = 2.51E-4
Liver: p = 0.00874
Adrenal Gland: p = 0.02
C3_OTHER_SKINOther malignant neoplasms of skinUK Biobank (UKBB)Neale Lab2018144023467925Spleen: p = 1.27E-5
Skin - Sun Exposed (Lower leg): p = 6.58E-4
Skin - Not Sun Exposed (Suprapubic): p = 0.00133
M13_FLEXIONFlexion deformityUK Biobank (UKBB)Neale Lab20181173610773Pituitary: p = 0.03
Muscle - Skeletal: p = 0.09
Brain - Cerebellar Hemisphere: p = 0.12
I9_CARDMYOOTHCardiomyopathy, other and unspecifiedUK Biobank (UKBB)Neale Lab20181643610303Spleen: p = 0.0011
Adipose - Subcutaneous: p = 0.00255
Breast - Mammary Tissue: p = 0.0069
K11_OTHILEUSOther or unspecified ileus, impaction or obstructionUK Biobank (UKBB)Neale Lab201813503598443Adipose - Subcutaneous: p = 0.04
Adipose - Visceral (Omentum): p = 0.04
Liver: p = 0.04
K11_GALLBILPANCDisorders of gallbladder, biliary tract and pancreasUK Biobank (UKBB)Neale Lab2018139223472725Liver: p = 1.21E-6
Stomach: p = 0.00125
Pancreas: p = 0.00703
M13_LOOSEJOINTLoose body in jointUK Biobank (UKBB)Neale Lab20181573610372Brain - Cerebellar Hemisphere: p = 0.00447
Pancreas: p = 0.00917
Brain - Cerebellum: p = 0.02
I9_PHLETHROMBDVTLOWDVT of lower extremitiesUK Biobank (UKBB)Neale Lab201821163590785Liver: p = 3.85E-6
Stomach: p = 7.41E-5
Colon - Sigmoid: p = 7.0E-4
G6_GUILBARGuillain-Barre syndromeUK Biobank (UKBB)Neale Lab20181553610393Breast - Mammary Tissue: p = 0.05
Minor Salivary Gland: p = 0.09
Spleen: p = 0.09
KRA_PSY_SCHIZODELSchizophrenia or delusionUK Biobank (UKBB)Neale Lab20184613607333Artery - Aorta: p = 0.00206
Artery - Coronary: p = 0.00206
Uterus: p = 0.00804
D3_BLOODNASOther and unspecified diseases of blood and blood-forming organsUK Biobank (UKBB)Neale Lab20181233610713Whole Blood: p = 8.66E-4
Prostate: p = 0.02
Liver: p = 0.03
C_KIDNEY_NOTRENALPELVISMalignant neoplasm of kidney, except renal pelvisUK Biobank (UKBB)Neale Lab20188713603233Uterus: p = 0.00106
Colon - Transverse: p = 0.00453
Muscle - Skeletal: p = 0.01
L12_INFECT_SKIN_OTHEROther local infections of skin and subcutaneous tissueUK Biobank (UKBB)Neale Lab20184933607012Testis: p = 0.02
Artery - Tibial: p = 0.03
Artery - Aorta: p = 0.07
I9_CHDMajor coronary heart disease eventUK Biobank (UKBB)Neale Lab2018101573510375Artery - Coronary: p = 2.72E-4
Artery - Tibial: p = 0.00135
Adipose - Visceral (Omentum): p = 0.00147
M13_SOFTTISSUEOTHOther soft tissue disorders, not elsewhere classifiedUK Biobank (UKBB)Neale Lab201872333539613Adipose - Visceral (Omentum): p = 0.00775
Liver: p = 0.01
Colon - Transverse: p = 0.01
134Number of self-reported cancersUK Biobank (UKBB)Neale Lab201803611365Kidney - Cortex: p = 0.02
Pituitary: p = 0.02
Spleen: p = 0.02
136Number of operations, self-reportedUK Biobank (UKBB)Neale Lab201803611415Prostate: p = 9.46E-4
Spleen: p = 0.00262
Skin - Not Sun Exposed (Suprapubic): p = 0.02
398Number of correct matches in roundUK Biobank (UKBB)Neale Lab201803606864Skin - Sun Exposed (Lower leg): p = 8.21E-4
Skin - Not Sun Exposed (Suprapubic): p = 0.00628
Brain - Cortex: p = 0.00786
403Number of times snap-button pressedUK Biobank (UKBB)Neale Lab201803596783Liver: p = 5.83E-4
Brain - Hippocampus: p = 0.00395
Brain - Amygdala: p = 0.00489
709Number in householdUK Biobank (UKBB)Neale Lab201803589633Ovary: p = 0.00156
Brain - Frontal Cortex (BA9): p = 0.00318
Pituitary: p = 0.00318
728Number of vehicles in householdUK Biobank (UKBB)Neale Lab201803587545Brain - Anterior cingulate cortex (BA24): p = 7.93E-7
Brain - Frontal Cortex (BA9): p = 6.37E-6
Brain - Hippocampus: p = 1.05E-5
738Average total household income before taxUK Biobank (UKBB)Neale Lab201803110284Uterus: p = 7.17E-7
Brain - Putamen (basal ganglia): p = 2.64E-5
Brain - Caudate (basal ganglia): p = 6.71E-5
777Frequency of travelling from home to job workplaceUK Biobank (UKBB)Neale Lab201802012673Lung: p = 3.26E-4
Artery - Aorta: p = 0.01
Muscle - Skeletal: p = 0.01
806Job involves mainly walking or standingUK Biobank (UKBB)Neale Lab201802049564Brain - Hippocampus: p = 4.57E-6
Brain - Putamen (basal ganglia): p = 1.63E-5
Brain - Caudate (basal ganglia): p = 2.99E-5
816Job involves heavy manual or physical workUK Biobank (UKBB)Neale Lab201802050004Brain - Nucleus accumbens (basal ganglia): p = 1.19E-6
Brain - Caudate (basal ganglia): p = 8.07E-6
Brain - Putamen (basal ganglia): p = 2.68E-5
826Job involves shift workUK Biobank (UKBB)Neale Lab201802047833Brain - Cortex: p = 3.98E-4
Brain - Nucleus accumbens (basal ganglia): p = 3.98E-4
Brain - Putamen (basal ganglia): p = 8.11E-4
845Age completed full time educationUK Biobank (UKBB)Neale Lab201802405474Brain - Putamen (basal ganglia): p = 1.96E-6
Brain - Frontal Cortex (BA9): p = 3.28E-6
Brain - Caudate (basal ganglia): p = 4.3E-6
864Number of days/week walked 10+ minutesUK Biobank (UKBB)Neale Lab201803550304Brain - Cortex: p = 6.59E-4
Brain - Frontal Cortex (BA9): p = 6.59E-4
Brain - Cerebellum: p = 0.00109
884Number of days/week of moderate physical activity 10+ minutesUK Biobank (UKBB)Neale Lab201803439434Brain - Cerebellar Hemisphere: p = 9.94E-6
Brain - Cerebellum: p = 9.94E-6
Brain - Caudate (basal ganglia): p = 1.78E-4
894Duration of moderate activityUK Biobank (UKBB)Neale Lab201802688264Adrenal Gland: p = 0.03
Brain - Cortex: p = 0.04
Brain - Caudate (basal ganglia): p = 0.06
904Number of days/week of vigorous physical activity 10+ minutesUK Biobank (UKBB)Neale Lab201803440844Brain - Cerebellum: p = 4.33E-4
Brain - Cortex: p = 4.33E-4
Brain - Frontal Cortex (BA9): p = 7.47E-4
924Usual walking paceUK Biobank (UKBB)Neale Lab201803589744Brain - Cerebellum: p = 2.07E-7
Brain - Cerebellar Hemisphere: p = 7.75E-6
Brain - Cortex: p = 1.9E-5
943Frequency of stair climbing in last 4 weeksUK Biobank (UKBB)Neale Lab201803577204Brain - Cerebellar Hemisphere: p = 1.2E-5
Brain - Cerebellum: p = 1.2E-5
Brain - Frontal Cortex (BA9): p = 4.13E-5
971Frequency of walking for pleasure in last 4 weeksUK Biobank (UKBB)Neale Lab201802574784Esophagus - Gastroesophageal Junction: p = 5.5E-5
Esophagus - Muscularis: p = 5.71E-4
Brain - Substantia nigra: p = 0.00127
981Duration walking for pleasureUK Biobank (UKBB)Neale Lab201802573304Brain - Caudate (basal ganglia): p = 2.28E-4
Brain - Putamen (basal ganglia): p = 3.6E-4
Brain - Nucleus accumbens (basal ganglia): p = 0.00879
991Frequency of strenuous sports in last 4 weeksUK Biobank (UKBB)Neale Lab20180368913Skin - Not Sun Exposed (Suprapubic): p = 0.00153
Esophagus - Mucosa: p = 0.00564
Esophagus - Muscularis: p = 0.00564
1001Duration of strenuous sportsUK Biobank (UKBB)Neale Lab20180369192Colon - Transverse: p = 0.00115
Liver: p = 0.00524
Adipose - Visceral (Omentum): p = 0.02
1011Frequency of light DIY in last 4 weeksUK Biobank (UKBB)Neale Lab201801804944Uterus: p = 9.3E-4
Whole Blood: p = 0.03
Artery - Coronary: p = 0.03
1021Duration of light DIYUK Biobank (UKBB)Neale Lab201801795484Pancreas: p = 0.0021
Artery - Tibial: p = 0.01
Brain - Putamen (basal ganglia): p = 0.02
1031Frequency of friend/family visitsUK Biobank (UKBB)Neale Lab201803588215Brain - Hippocampus: p = 2.07E-6
Brain - Amygdala: p = 1.42E-5
Brain - Spinal cord (cervical c-1): p = 1.42E-5
1050Time spend outdoors in summerUK Biobank (UKBB)Neale Lab201803277174Brain - Cortex: p = 9.09E-7
Brain - Amygdala: p = 1.61E-6
Brain - Anterior cingulate cortex (BA24): p = 1.61E-6
1060Time spent outdoors in winterUK Biobank (UKBB)Neale Lab201802848895Brain - Anterior cingulate cortex (BA24): p = 2.27E-5
Brain - Putamen (basal ganglia): p = 5.55E-5
Brain - Caudate (basal ganglia): p = 8.54E-5
1070Time spent watching television (TV)UK Biobank (UKBB)Neale Lab201803418593Brain - Caudate (basal ganglia): p = 1.39E-6
Brain - Putamen (basal ganglia): p = 1.39E-6
Brain - Hippocampus: p = 9.18E-6
1080Time spent using computerUK Biobank (UKBB)Neale Lab201802807504Brain - Amygdala: p = 1.8E-6
Brain - Caudate (basal ganglia): p = 3.06E-6
Brain - Putamen (basal ganglia): p = 6.69E-6
1090Time spent drivingUK Biobank (UKBB)Neale Lab201802413575Brain - Caudate (basal ganglia): p = 0.01
Adrenal Gland: p = 0.01
Brain - Frontal Cortex (BA9): p = 0.01
1100Drive faster than motorway speed limitUK Biobank (UKBB)Neale Lab201803271924Brain - Cortex: p = 1.53E-4
Brain - Frontal Cortex (BA9): p = 1.53E-4
Brain - Putamen (basal ganglia): p = 2.03E-4
1110Length of mobile phone useUK Biobank (UKBB)Neale Lab201803566184Brain - Caudate (basal ganglia): p = 1.04E-4
Brain - Nucleus accumbens (basal ganglia): p = 3.12E-4
Brain - Anterior cingulate cortex (BA24): p = 5.37E-4
1120Weekly usage of mobile phone in last 3 monthsUK Biobank (UKBB)Neale Lab201803011575Brain - Nucleus accumbens (basal ganglia): p = 3.91E-4
Brain - Hypothalamus: p = 6.73E-4
Brain - Cerebellar Hemisphere: p = 7.38E-4
1130Hands-free device/speakerphone use with mobile phone in last 3 monthUK Biobank (UKBB)Neale Lab201803027335Brain - Anterior cingulate cortex (BA24): p = 2.42E-4
Brain - Cortex: p = 3.75E-4
Brain - Hippocampus: p = 3.75E-4
1140Difference in mobile phone use compared to two years previouslyUK Biobank (UKBB)Neale Lab201802982393Artery - Tibial: p = 0.00723
Artery - Aorta: p = 0.00739
Artery - Coronary: p = 0.02
1160Sleep durationUK Biobank (UKBB)Neale Lab201803590204Brain - Frontal Cortex (BA9): p = 5.35E-7
Brain - Caudate (basal ganglia): p = 1.66E-6
Brain - Hippocampus: p = 2.87E-6
1170Getting up in morningUK Biobank (UKBB)Neale Lab201803602314Brain - Cortex: p = 5.31E-12
Brain - Frontal Cortex (BA9): p = 5.31E-12
Brain - Hippocampus: p = 1.02E-10
1180Morning/evening person (chronotype)UK Biobank (UKBB)Neale Lab201803224883Brain - Substantia nigra: p = 7.4E-5
Brain - Nucleus accumbens (basal ganglia): p = 1.26E-4
Brain - Caudate (basal ganglia): p = 2.12E-4
1190Nap during dayUK Biobank (UKBB)Neale Lab201803608554Brain - Cortex: p = 5.53E-8
Brain - Frontal Cortex (BA9): p = 8.06E-8
Brain - Caudate (basal ganglia): p = 9.97E-8
1200Sleeplessness / insomniaUK Biobank (UKBB)Neale Lab201803607384Brain - Substantia nigra: p = 7.83E-4
Artery - Tibial: p = 0.00171
Muscle - Skeletal: p = 0.00176
1220Daytime dozing / sleeping (narcolepsy)UK Biobank (UKBB)Neale Lab201803597524Brain - Cerebellar Hemisphere: p = 1.51E-4
Brain - Hypothalamus: p = 2.57E-4
Brain - Substantia nigra: p = 2.57E-4
1239Current tobacco smokingUK Biobank (UKBB)Neale Lab201803607974Heart - Atrial Appendage: p = 1.81E-4
Brain - Nucleus accumbens (basal ganglia): p = 3.16E-4
Esophagus - Muscularis: p = 3.16E-4
1249Past tobacco smokingUK Biobank (UKBB)Neale Lab201803321414Brain - Caudate (basal ganglia): p = 6.57E-7
Brain - Frontal Cortex (BA9): p = 6.57E-7
Brain - Nucleus accumbens (basal ganglia): p = 6.57E-7
1259Smoking/smokers in householdUK Biobank (UKBB)Neale Lab201803325734Brain - Cerebellar Hemisphere: p = 0.01
Brain - Putamen (basal ganglia): p = 0.01
Brain - Substantia nigra: p = 0.01
1269Exposure to tobacco smoke at homeUK Biobank (UKBB)Neale Lab201803266763Brain - Nucleus accumbens (basal ganglia): p = 0.00137
Brain - Caudate (basal ganglia): p = 0.00307
Brain - Putamen (basal ganglia): p = 0.00653
1279Exposure to tobacco smoke outside homeUK Biobank (UKBB)Neale Lab201803061915Brain - Cerebellum: p = 7.41E-4
Brain - Nucleus accumbens (basal ganglia): p = 0.00118
Brain - Putamen (basal ganglia): p = 0.0017
1289Cooked vegetable intakeUK Biobank (UKBB)Neale Lab201803504044Brain - Cerebellar Hemisphere: p = 2.75E-4
Brain - Amygdala: p = 8.19E-4
Brain - Anterior cingulate cortex (BA24): p = 8.19E-4
1299Salad / raw vegetable intakeUK Biobank (UKBB)Neale Lab201803396014Whole Blood: p = 0.00226
Uterus: p = 0.00625
Esophagus - Gastroesophageal Junction: p = 0.00928
1309Fresh fruit intakeUK Biobank (UKBB)Neale Lab201803482844Brain - Cerebellar Hemisphere: p = 3.59E-4
Adrenal Gland: p = 0.00135
Brain - Cerebellum: p = 0.00172
1319Dried fruit intakeUK Biobank (UKBB)Neale Lab201803291344Spleen: p = 3.0E-4
Brain - Cortex: p = 0.00109
Brain - Cerebellar Hemisphere: p = 0.00154
1329Oily fish intakeUK Biobank (UKBB)Neale Lab201803593404Spleen: p = 5.44E-6
Brain - Cerebellum: p = 0.00143
Brain - Frontal Cortex (BA9): p = 0.00143
1339Non-oily fish intakeUK Biobank (UKBB)Neale Lab201803596825Skin - Sun Exposed (Lower leg): p = 1.78E-6
Skin - Not Sun Exposed (Suprapubic): p = 1.35E-5
Brain - Caudate (basal ganglia): p = 1.34E-4
1349Processed meat intakeUK Biobank (UKBB)Neale Lab201803604684Brain - Cerebellar Hemisphere: p = 2.86E-6
Brain - Cerebellum: p = 2.86E-6
Brain - Cortex: p = 4.14E-4
1359Poultry intakeUK Biobank (UKBB)Neale Lab201803603905Brain - Hypothalamus: p = 1.81E-4
Brain - Cortex: p = 6.07E-4
Brain - Amygdala: p = 6.16E-4
1369Beef intakeUK Biobank (UKBB)Neale Lab201803597844Brain - Cortex: p = 2.26E-5
Brain - Anterior cingulate cortex (BA24): p = 0.00136
Brain - Frontal Cortex (BA9): p = 0.00136
1379Lamb/mutton intakeUK Biobank (UKBB)Neale Lab201803590024Brain - Cortex: p = 3.2E-6
Brain - Frontal Cortex (BA9): p = 4.19E-5
Brain - Anterior cingulate cortex (BA24): p = 2.4E-4
1389Pork intakeUK Biobank (UKBB)Neale Lab201803591155Brain - Substantia nigra: p = 6.76E-5
Brain - Putamen (basal ganglia): p = 0.00131
Brain - Hypothalamus: p = 0.0016
1408Cheese intakeUK Biobank (UKBB)Neale Lab201803524584Brain - Frontal Cortex (BA9): p = 2.13E-5
Brain - Cortex: p = 3.52E-5
Brain - Caudate (basal ganglia): p = 9.21E-5
1458Cereal intakeUK Biobank (UKBB)Neale Lab201803450194Brain - Amygdala: p = 1.63E-5
Brain - Anterior cingulate cortex (BA24): p = 1.37E-4
Brain - Cerebellum: p = 3.65E-4
1478Salt added to foodUK Biobank (UKBB)Neale Lab201803609544Brain - Hippocampus: p = 4.28E-4
Brain - Hypothalamus: p = 9.68E-4
Brain - Spinal cord (cervical c-1): p = 9.68E-4
1498Coffee intakeUK Biobank (UKBB)Neale Lab201803346594Liver: p = 0.0082
Adrenal Gland: p = 0.00956
Nerve - Tibial: p = 0.00956
1518Hot drink temperatureUK Biobank (UKBB)Neale Lab201803572564Brain - Caudate (basal ganglia): p = 4.98E-5
Brain - Putamen (basal ganglia): p = 7.86E-5
Brain - Frontal Cortex (BA9): p = 1.23E-4
1528Water intakeUK Biobank (UKBB)Neale Lab201803333634Brain - Cerebellar Hemisphere: p = 8.47E-7
Brain - Cortex: p = 4.95E-6
Brain - Frontal Cortex (BA9): p = 4.95E-6
1548Variation in dietUK Biobank (UKBB)Neale Lab201803597524Brain - Nucleus accumbens (basal ganglia): p = 1.06E-6
Brain - Anterior cingulate cortex (BA24): p = 3.05E-6
Brain - Frontal Cortex (BA9): p = 3.05E-6
1558Alcohol intake frequency.UK Biobank (UKBB)Neale Lab201803607264Brain - Cerebellum: p = 2.55E-7
Brain - Cerebellar Hemisphere: p = 2.13E-6
Brain - Cortex: p = 2.13E-6
1568Average weekly red wine intakeUK Biobank (UKBB)Neale Lab201802577735Brain - Frontal Cortex (BA9): p = 2.61E-4
Brain - Cerebellar Hemisphere: p = 6.82E-4
Brain - Cerebellum: p = 6.82E-4
1578Average weekly champagne plus white wine intakeUK Biobank (UKBB)Neale Lab201802576235Brain - Cerebellum: p = 2.54E-7
Brain - Hippocampus: p = 3.73E-6
Brain - Cerebellar Hemisphere: p = 6.18E-6
1588Average weekly beer plus cider intakeUK Biobank (UKBB)Neale Lab201802582565Brain - Frontal Cortex (BA9): p = 0.00281
Brain - Spinal cord (cervical c-1): p = 0.00404
Heart - Atrial Appendage: p = 0.00518
1598Average weekly spirits intakeUK Biobank (UKBB)Neale Lab201802574265Brain - Frontal Cortex (BA9): p = 1.47E-4
Brain - Amygdala: p = 2.29E-4
Brain - Anterior cingulate cortex (BA24): p = 2.29E-4
1608Average weekly fortified wine intakeUK Biobank (UKBB)Neale Lab201802581913Whole Blood: p = 0.02
Artery - Aorta: p = 0.02
Brain - Cerebellum: p = 0.04
1628Alcohol intake versus 10 years previouslyUK Biobank (UKBB)Neale Lab201803349895Liver: p = 0.00193
Pancreas: p = 0.00229
Brain - Frontal Cortex (BA9): p = 0.00818
1687Comparative body size at age 10UK Biobank (UKBB)Neale Lab201803549963Colon - Sigmoid: p = 9.77E-4
Brain - Hippocampus: p = 0.00212
Brain - Cerebellum: p = 0.00306
1717Skin colourUK Biobank (UKBB)Neale Lab201803565304Skin - Sun Exposed (Lower leg): p = 1.49E-5
Skin - Not Sun Exposed (Suprapubic): p = 6.19E-5
Colon - Sigmoid: p = 0.00184
1727Ease of skin tanningUK Biobank (UKBB)Neale Lab201803536974Adipose - Subcutaneous: p = 0.01
Colon - Sigmoid: p = 0.02
Esophagus - Muscularis: p = 0.02
1737Childhood sunburn occasionsUK Biobank (UKBB)Neale Lab201802697344Spleen: p = 1.17E-5
Lung: p = 0.00778
Uterus: p = 0.02
1757Facial ageingUK Biobank (UKBB)Neale Lab201803304094Artery - Coronary: p = 1.18E-4
Artery - Aorta: p = 2.91E-4
Artery - Tibial: p = 2.91E-4
1873Number of full brothersUK Biobank (UKBB)Neale Lab201803553263Brain - Cerebellar Hemisphere: p = 2.31E-4
Brain - Cerebellum: p = 2.31E-4
Esophagus - Muscularis: p = 2.58E-4
1883Number of full sistersUK Biobank (UKBB)Neale Lab201803553904Muscle - Skeletal: p = 0.00219
Small Intestine - Terminal Ileum: p = 0.00597
Brain - Nucleus accumbens (basal ganglia): p = 0.00601
2050Frequency of depressed mood in last 2 weeksUK Biobank (UKBB)Neale Lab201803459575Brain - Cortex: p = 3.15E-6
Brain - Frontal Cortex (BA9): p = 5.64E-6
Brain - Amygdala: p = 1.41E-4
2060Frequency of unenthusiasm / disinterest in last 2 weeksUK Biobank (UKBB)Neale Lab201803496315Brain - Nucleus accumbens (basal ganglia): p = 1.54E-4
Brain - Caudate (basal ganglia): p = 2.31E-4
Brain - Frontal Cortex (BA9): p = 8.33E-4
2070Frequency of tenseness / restlessness in last 2 weeksUK Biobank (UKBB)Neale Lab201803479654Liver: p = 0.00458
Brain - Nucleus accumbens (basal ganglia): p = 0.00654
Brain - Putamen (basal ganglia): p = 0.00654
2080Frequency of tiredness / lethargy in last 2 weeksUK Biobank (UKBB)Neale Lab201803505804Brain - Frontal Cortex (BA9): p = 3.04E-5
Brain - Amygdala: p = 8.47E-5
Brain - Cortex: p = 2.24E-4
2110Able to confideUK Biobank (UKBB)Neale Lab201803506184Brain - Caudate (basal ganglia): p = 1.13E-6
Brain - Putamen (basal ganglia): p = 4.68E-6
Brain - Amygdala: p = 2.13E-4
2149Lifetime number of sexual partnersUK Biobank (UKBB)Neale Lab201802966094Brain - Cerebellar Hemisphere: p = 0.0052
Brain - Caudate (basal ganglia): p = 0.00599
Brain - Putamen (basal ganglia): p = 0.00599
2178Overall health ratingUK Biobank (UKBB)Neale Lab201803596814Brain - Amygdala: p = 2.24E-7
Brain - Caudate (basal ganglia): p = 2.24E-7
Brain - Putamen (basal ganglia): p = 1.06E-6
2237Plays computer gamesUK Biobank (UKBB)Neale Lab201803608174Brain - Amygdala: p = 4.63E-9
Brain - Putamen (basal ganglia): p = 8.79E-9
Brain - Caudate (basal ganglia): p = 1.65E-8
2267Use of sun/uv protectionUK Biobank (UKBB)Neale Lab201803585594Brain - Caudate (basal ganglia): p = 3.76E-4
Brain - Amygdala: p = 5.92E-4
Brain - Cortex: p = 5.92E-4
2277Frequency of solarium/sunlamp useUK Biobank (UKBB)Neale Lab201803406433Brain - Caudate (basal ganglia): p = 2.81E-4
Brain - Hippocampus: p = 4.5E-4
Brain - Putamen (basal ganglia): p = 7.09E-4
2296Falls in the last yearUK Biobank (UKBB)Neale Lab201803603444Kidney - Cortex: p = 1.27E-4
Adrenal Gland: p = 0.00261
Brain - Amygdala: p = 0.00308
2306Weight change compared with 1 year agoUK Biobank (UKBB)Neale Lab201803551294Adrenal Gland: p = 0.00308
Liver: p = 0.01
Brain - Spinal cord (cervical c-1): p = 0.03
2355Most recent bowel cancer screeningUK Biobank (UKBB)Neale Lab20180814083Adipose - Visceral (Omentum): p = 4.03E-4
Adipose - Subcutaneous: p = 0.00639
Breast - Mammary Tissue: p = 0.00639
2375Relative age of first facial hairUK Biobank (UKBB)Neale Lab201801614704Pituitary: p = 0.00161
Skin - Sun Exposed (Lower leg): p = 0.00279
Uterus: p = 0.00279
2385Relative age voice brokeUK Biobank (UKBB)Neale Lab201801544595Colon - Sigmoid: p = 0.00632
Pituitary: p = 0.00632
Uterus: p = 0.00967
2405Number of children fatheredUK Biobank (UKBB)Neale Lab201801654923Brain - Hippocampus: p = 8.53E-4
Brain - Frontal Cortex (BA9): p = 0.00354
Brain - Nucleus accumbens (basal ganglia): p = 0.00354
2624Frequency of heavy DIY in last 4 weeksUK Biobank (UKBB)Neale Lab201801451903Small Intestine - Terminal Ileum: p = 0.0012
Liver: p = 0.00571
Uterus: p = 0.00571
2634Duration of heavy DIYUK Biobank (UKBB)Neale Lab201801453734Brain - Cerebellar Hemisphere: p = 0.01
Adrenal Gland: p = 0.02
Brain - Cerebellum: p = 0.03
2684Years since last breast cancer screening / mammogramUK Biobank (UKBB)Neale Lab201801156703Thyroid: p = 0.01
Colon - Sigmoid: p = 0.02
Colon - Transverse: p = 0.05
2704Years since last cervical smear testUK Biobank (UKBB)Neale Lab201801491963Lung: p = 0.00294
Uterus: p = 0.00641
Skin - Sun Exposed (Lower leg): p = 0.03
2714Age when periods started (menarche)UK Biobank (UKBB)Neale Lab201801886443Brain - Cerebellar Hemisphere: p = 9.56E-5
Brain - Cerebellum: p = 9.56E-5
Pituitary: p = 9.86E-4
2744Birth weight of first childUK Biobank (UKBB)Neale Lab201801552024Artery - Tibial: p = 3.76E-7
Artery - Aorta: p = 1.97E-4
Liver: p = 3.4E-4
2887Number of cigarettes previously smoked dailyUK Biobank (UKBB)Neale Lab20180844565Artery - Coronary: p = 1.38E-4
Uterus: p = 2.74E-4
Brain - Hypothalamus: p = 0.00254
2926Number of unsuccessful stop-smoking attemptsUK Biobank (UKBB)Neale Lab20180810265Testis: p = 8.82E-5
Colon - Sigmoid: p = 0.00119
Heart - Atrial Appendage: p = 0.00801
2936Likelihood of resuming smokingUK Biobank (UKBB)Neale Lab20180872333Brain - Hypothalamus: p = 0.00738
Brain - Substantia nigra: p = 0.02
Adrenal Gland: p = 0.03
3426Job involve night shift workUK Biobank (UKBB)Neale Lab20180333732Brain - Cerebellum: p = 4.78E-4
Brain - Cerebellar Hemisphere: p = 0.00222
Adipose - Subcutaneous: p = 0.02
3456Number of cigarettes currently smoked daily (current cigarette smokers)UK Biobank (UKBB)Neale Lab20180253485Brain - Cerebellum: p = 0.00322
Brain - Spinal cord (cervical c-1): p = 0.00322
Spleen: p = 0.00401
3466Time from waking to first cigaretteUK Biobank (UKBB)Neale Lab20180254144Liver: p = 6.29E-4
Prostate: p = 0.00551
Brain - Cerebellum: p = 0.00856
3476Difficulty not smoking for 1 dayUK Biobank (UKBB)Neale Lab20180254873Spleen: p = 3.99E-4
Heart - Atrial Appendage: p = 0.00993
Colon - Sigmoid: p = 0.01
3486Ever tried to stop smokingUK Biobank (UKBB)Neale Lab20180274673Skin - Sun Exposed (Lower leg): p = 7.25E-4
Brain - Substantia nigra: p = 0.00153
Skin - Not Sun Exposed (Suprapubic): p = 0.00315
3496Wants to stop smokingUK Biobank (UKBB)Neale Lab20180271783Testis: p = 0.00321
Colon - Sigmoid: p = 0.00416
Lung: p = 0.04
3637Frequency of other exercises in last 4 weeksUK Biobank (UKBB)Neale Lab201801725053Artery - Tibial: p = 0.04
Prostate: p = 0.04
Vagina: p = 0.04
3647Duration of other exercisesUK Biobank (UKBB)Neale Lab201801726503Prostate: p = 0.00454
Thyroid: p = 0.01
Pancreas: p = 0.03
3669Lifetime number of same-sex sexual partnersUK Biobank (UKBB)Neale Lab2018093873Whole Blood: p = 0.00592
Lung: p = 0.01
Liver: p = 0.02
3710Length of menstrual cycleUK Biobank (UKBB)Neale Lab20180328473Thyroid: p = 1.21E-5
Vagina: p = 0.00311
Pituitary: p = 0.00458
3829Number of stillbirthsUK Biobank (UKBB)Neale Lab20180604533Whole Blood: p = 0.0051
Spleen: p = 0.03
Thyroid: p = 0.04
3839Number of spontaneous miscarriagesUK Biobank (UKBB)Neale Lab20180603003Lung: p = 2.93E-4
Spleen: p = 0.00164
Adipose - Subcutaneous: p = 0.05
3849Number of pregnancy terminationsUK Biobank (UKBB)Neale Lab20180600993Brain - Cerebellar Hemisphere: p = 0.00731
Adipose - Subcutaneous: p = 0.02
Stomach: p = 0.02
4260Round of numeric memory testUK Biobank (UKBB)Neale Lab20180375753Pancreas: p = 1.06E-4
Brain - Cerebellar Hemisphere: p = 0.0059
Brain - Cerebellum: p = 0.0059
4269Number of triplets attempted (left)UK Biobank (UKBB)Neale Lab201801178523Ovary: p = 2.14E-4
Adipose - Visceral (Omentum): p = 0.01
Nerve - Tibial: p = 0.01
4270Volume level set by participant (left)UK Biobank (UKBB)Neale Lab201801167903Muscle - Skeletal: p = 0.0022
Brain - Cerebellum: p = 0.02
Skin - Not Sun Exposed (Suprapubic): p = 0.04
4276Number of triplets attempted (right)UK Biobank (UKBB)Neale Lab201801179032Ovary: p = 0.00974
Pancreas: p = 0.01
Colon - Sigmoid: p = 0.02
4277Volume level set by participant (right)UK Biobank (UKBB)Neale Lab201801167553Breast - Mammary Tissue: p = 0.00321
Brain - Hypothalamus: p = 0.04
Adipose - Visceral (Omentum): p = 0.04
4282Maximum digits remembered correctlyUK Biobank (UKBB)Neale Lab20180368843Pancreas: p = 0.00126
Brain - Cerebellum: p = 0.00455
Brain - Cerebellar Hemisphere: p = 0.01
4283Number of rounds of numeric memory test performedUK Biobank (UKBB)Neale Lab20180376463Pancreas: p = 1.06E-4
Brain - Cerebellar Hemisphere: p = 0.00171
Brain - Cerebellum: p = 0.00171
4407Average monthly red wine intakeUK Biobank (UKBB)Neale Lab20180262293Pituitary: p = 7.97E-4
Spleen: p = 0.00219
Whole Blood: p = 0.08
4418Average monthly champagne plus white wine intakeUK Biobank (UKBB)Neale Lab20180261983Heart - Atrial Appendage: p = 0.00416
Heart - Left Ventricle: p = 0.00416
Brain - Cerebellar Hemisphere: p = 0.00968
4429Average monthly beer plus cider intakeUK Biobank (UKBB)Neale Lab20180262853Ovary: p = 0.00337
Brain - Spinal cord (cervical c-1): p = 0.01
Nerve - Tibial: p = 0.02
4440Average monthly spirits intakeUK Biobank (UKBB)Neale Lab20180261933Pancreas: p = 0.00169
Skin - Not Sun Exposed (Suprapubic): p = 0.00321
Skin - Sun Exposed (Lower leg): p = 0.00321
4451Average monthly fortified wine intakeUK Biobank (UKBB)Neale Lab20180263282Testis: p = 0.02
Esophagus - Muscularis: p = 0.03
Liver: p = 0.05
4462Average monthly intake of other alcoholic drinksUK Biobank (UKBB)Neale Lab20180263593Whole Blood: p = 0.0076
Brain - Hypothalamus: p = 0.01
Brain - Substantia nigra: p = 0.01
4526HappinessUK Biobank (UKBB)Neale Lab201801195354Brain - Anterior cingulate cortex (BA24): p = 6.6E-5
Brain - Hypothalamus: p = 6.6E-5
Brain - Amygdala: p = 1.68E-4
4537Work/job satisfactionUK Biobank (UKBB)Neale Lab20180821903Skin - Sun Exposed (Lower leg): p = 0.02
Testis: p = 0.02
Skin - Not Sun Exposed (Suprapubic): p = 0.05
4548Health satisfactionUK Biobank (UKBB)Neale Lab201801195674Minor Salivary Gland: p = 0.00626
Skin - Not Sun Exposed (Suprapubic): p = 0.01
Brain - Amygdala: p = 0.01
4559Family relationship satisfactionUK Biobank (UKBB)Neale Lab201801188183Esophagus - Gastroesophageal Junction: p = 0.00522
Muscle - Skeletal: p = 0.00522
Esophagus - Muscularis: p = 0.00732
4570Friendships satisfactionUK Biobank (UKBB)Neale Lab201801186494Esophagus - Muscularis: p = 0.0038
Lung: p = 0.00888
Esophagus - Gastroesophageal Junction: p = 0.01
4581Financial situation satisfactionUK Biobank (UKBB)Neale Lab201801193944Brain - Frontal Cortex (BA9): p = 0.02
Nerve - Tibial: p = 0.02
Prostate: p = 0.02
4620Number of depression episodesUK Biobank (UKBB)Neale Lab20180456953Ovary: p = 0.00224
Brain - Anterior cingulate cortex (BA24): p = 0.00367
Brain - Frontal Cortex (BA9): p = 0.00367
4674Private healthcareUK Biobank (UKBB)Neale Lab201801193004Skin - Not Sun Exposed (Suprapubic): p = 0.00539
Colon - Sigmoid: p = 0.00739
Uterus: p = 0.00739
4814Tinnitus severity/nuisanceUK Biobank (UKBB)Neale Lab20180340183Lung: p = 0.00126
Colon - Sigmoid: p = 0.00543
Heart - Left Ventricle: p = 0.00678
4825Noisy workplaceUK Biobank (UKBB)Neale Lab201801189724Pancreas: p = 1.96E-4
Brain - Cerebellum: p = 4.78E-4
Brain - Caudate (basal ganglia): p = 0.00512
4836Loud music exposure frequencyUK Biobank (UKBB)Neale Lab201801183993Minor Salivary Gland: p = 1.56E-4
Brain - Cerebellar Hemisphere: p = 0.00498
Brain - Cerebellum: p = 0.00498
5057Number of older siblingsUK Biobank (UKBB)Neale Lab201801034533Adipose - Visceral (Omentum): p = 9.02E-4
Adipose - Subcutaneous: p = 0.00959
Brain - Spinal cord (cervical c-1): p = 0.00968
5221Index of best refractometry result (right)UK Biobank (UKBB)Neale Lab20180779834Pituitary: p = 0.002
Small Intestine - Terminal Ileum: p = 0.01
Spleen: p = 0.02
52373mm index of best keratometry results (right)UK Biobank (UKBB)Neale Lab20180754102Colon - Sigmoid: p = 0.00637
Ovary: p = 0.04
Adrenal Gland: p = 0.05
52516mm index of best keratometry results (right)UK Biobank (UKBB)Neale Lab20180662563Esophagus - Gastroesophageal Junction: p = 0.01
Small Intestine - Terminal Ileum: p = 0.01
Prostate: p = 0.02
5276Index of best refractometry result (left)UK Biobank (UKBB)Neale Lab20180777393Skin - Not Sun Exposed (Suprapubic): p = 0.03
Colon - Transverse: p = 0.04
Adipose - Subcutaneous: p = 0.09
52923mm index of best keratometry results (left)UK Biobank (UKBB)Neale Lab20180753982Whole Blood: p = 6.39E-4
Brain - Spinal cord (cervical c-1): p = 0.02
Thyroid: p = 0.02
53066mm index of best keratometry results (left)UK Biobank (UKBB)Neale Lab20180655513Artery - Coronary: p = 0.005
Brain - Amygdala: p = 0.00672
Esophagus - Gastroesophageal Junction: p = 0.01
5364Average weekly intake of other alcoholic drinksUK Biobank (UKBB)Neale Lab20180854202Pancreas: p = 0.02
Esophagus - Muscularis: p = 0.05
Brain - Spinal cord (cervical c-1): p = 0.07
5386Number of unenthusiastic/disinterested episodesUK Biobank (UKBB)Neale Lab20180300013Brain - Hippocampus: p = 0.00492
Brain - Frontal Cortex (BA9): p = 0.00952
Brain - Anterior cingulate cortex (BA24): p = 0.01
5507Leg pain on walking : action takenUK Biobank (UKBB)Neale Lab20180255693Pancreas: p = 1.69E-5
Artery - Aorta: p = 4.64E-4
Artery - Coronary: p = 7.81E-4
670_1Type of accommodation lived in: A house or bungalowUK Biobank (UKBB)Neale Lab2018326854332344Brain - Hippocampus: p = 1.12E-4
Brain - Hypothalamus: p = 2.98E-4
Brain - Amygdala: p = 4.75E-4
670_2Type of accommodation lived in: A flat, maisonette or apartmentUK Biobank (UKBB)Neale Lab2018318513282374Brain - Hippocampus: p = 0.00679
Brain - Spinal cord (cervical c-1): p = 0.01
Brain - Amygdala: p = 0.02
670_3Type of accommodation lived in: Mobile or temporary structure (i.e. caravan)UK Biobank (UKBB)Neale Lab20184843596043Kidney - Cortex: p = 0.00566
Brain - Substantia nigra: p = 0.01
Brain - Hypothalamus: p = 0.03
670_4Type of accommodation lived in: Sheltered accommodationUK Biobank (UKBB)Neale Lab20188593592293Adrenal Gland: p = 0.00167
Colon - Sigmoid: p = 0.00519
Skin - Sun Exposed (Lower leg): p = 0.04
680_1Own or rent accommodation lived in: Own outright (by you or someone in your household)UK Biobank (UKBB)Neale Lab20181933581629824Brain - Anterior cingulate cortex (BA24): p = 2.91E-7
Brain - Cortex: p = 5.01E-7
Brain - Cerebellar Hemisphere: p = 8.54E-7
680_2Own or rent accommodation lived in: Own with a mortgageUK Biobank (UKBB)Neale Lab20181312332251073Brain - Hypothalamus: p = 0.03
Brain - Cerebellar Hemisphere: p = 0.03
Brain - Cerebellum: p = 0.03
680_3Own or rent accommodation lived in: Rent - from local authority, local council, housing associationUK Biobank (UKBB)Neale Lab2018189683373723Brain - Caudate (basal ganglia): p = 2.07E-4
Brain - Putamen (basal ganglia): p = 2.07E-4
Brain - Nucleus accumbens (basal ganglia): p = 0.00107
680_4Own or rent accommodation lived in: Rent - from private landlord or letting agencyUK Biobank (UKBB)Neale Lab201894533468873Muscle - Skeletal: p = 0.00299
Brain - Caudate (basal ganglia): p = 0.04
Ovary: p = 0.05
680_5Own or rent accommodation lived in: Pay part rent and part mortgage (shared ownership)UK Biobank (UKBB)Neale Lab20189193554212Lung: p = 0.03
Adrenal Gland: p = 0.06
Colon - Transverse: p = 0.06
680_6Own or rent accommodation lived in: Live in accommodation rent freeUK Biobank (UKBB)Neale Lab201824093539313Stomach: p = 2.54E-4
Minor Salivary Gland: p = 0.00356
Adipose - Subcutaneous: p = 0.02
1150_2Usual side of head for mobile phone use: RightUK Biobank (UKBB)Neale Lab20181753551276545Brain - Cerebellum: p = 0.00235
Esophagus - Gastroesophageal Junction: p = 0.00567
Brain - Cerebellar Hemisphere: p = 0.00735
1150_1Usual side of head for mobile phone use: LeftUK Biobank (UKBB)Neale Lab20181078021952075Brain - Cerebellum: p = 0.00652
Brain - Cerebellar Hemisphere: p = 0.00907
Brain - Substantia nigra: p = 0.04
1150_3Usual side of head for mobile phone use: Equally left and rightUK Biobank (UKBB)Neale Lab2018198522831573Brain - Nucleus accumbens (basal ganglia): p = 6.21E-4
Brain - Amygdala: p = 0.0015
Brain - Caudate (basal ganglia): p = 0.00227
1210SnoringUK Biobank (UKBB)Neale Lab20181256562106644Kidney - Cortex: p = 8.56E-5
Artery - Tibial: p = 0.0017
Colon - Transverse: p = 0.00361
1418_2Milk type used: Semi-skimmedUK Biobank (UKBB)Neale Lab20182348701259363Brain - Amygdala: p = 0.01
Brain - Anterior cingulate cortex (BA24): p = 0.01
Brain - Cortex: p = 0.01
1418_1Milk type used: Full creamUK Biobank (UKBB)Neale Lab2018229023379044Liver: p = 0.00376
Stomach: p = 0.02
Artery - Aorta: p = 0.02
1418_3Milk type used: SkimmedUK Biobank (UKBB)Neale Lab2018740872867195Brain - Hippocampus: p = 9.48E-4
Brain - Substantia nigra: p = 9.48E-4
Brain - Amygdala: p = 0.00652
1418_4Milk type used: SoyaUK Biobank (UKBB)Neale Lab2018131473476593Whole Blood: p = 0.02
Stomach: p = 0.03
Minor Salivary Gland: p = 0.03
1418_5Milk type used: Other type of milkUK Biobank (UKBB)Neale Lab201842133565933Adipose - Subcutaneous: p = 0.02
Adipose - Visceral (Omentum): p = 0.02
Pancreas: p = 0.02
1418_6Milk type used: Never/rarely have milkUK Biobank (UKBB)Neale Lab2018115873492194Esophagus - Mucosa: p = 0.00134
Vagina: p = 0.00523
Brain - Amygdala: p = 0.0065
1428_3Spread type: Other type of spread/margarineUK Biobank (UKBB)Neale Lab20181905931696985Adrenal Gland: p = 2.65E-4
Skin - Sun Exposed (Lower leg): p = 0.00451
Brain - Putamen (basal ganglia): p = 0.00625
1428_0Spread type: Never/rarely use spreadUK Biobank (UKBB)Neale Lab2018365793237124Artery - Tibial: p = 8.37E-4
Artery - Aorta: p = 0.00121
Adrenal Gland: p = 0.02
1428_1Spread type: Butter/spreadable butterUK Biobank (UKBB)Neale Lab20181311902291015Adrenal Gland: p = 4.99E-5
Nerve - Tibial: p = 0.00111
Colon - Sigmoid: p = 0.00185
1428_2Spread type: Flora Pro-Active/BenecolUK Biobank (UKBB)Neale Lab201819293583622Artery - Coronary: p = 0.0018
Artery - Aorta: p = 0.01
Artery - Tibial: p = 0.02
1448_3Bread type: Wholemeal or wholegrainUK Biobank (UKBB)Neale Lab20182010131474114Brain - Hippocampus: p = 1.35E-7
Brain - Hypothalamus: p = 2.62E-7
Brain - Amygdala: p = 5.02E-7
1448_1Bread type: WhiteUK Biobank (UKBB)Neale Lab2018914522569724Brain - Cerebellar Hemisphere: p = 1.34E-5
Brain - Hippocampus: p = 2.31E-5
Brain - Caudate (basal ganglia): p = 1.1E-4
1448_2Bread type: BrownUK Biobank (UKBB)Neale Lab2018415183069064Brain - Frontal Cortex (BA9): p = 4.02E-4
Whole Blood: p = 4.97E-4
Brain - Anterior cingulate cortex (BA24): p = 8.85E-4
1448_4Bread type: Other type of breadUK Biobank (UKBB)Neale Lab2018144413339835Spleen: p = 2.13E-10
Lung: p = 5.14E-8
Whole Blood: p = 3.6E-5
1468_3Cereal type: Oat cereal (e.g. Ready Brek, porridge)UK Biobank (UKBB)Neale Lab2018763512235474Lung: p = 2.03E-4
Spleen: p = 2.03E-4
Adipose - Subcutaneous: p = 0.02
1468_1Cereal type: Bran cereal (e.g. All Bran, Branflakes)UK Biobank (UKBB)Neale Lab2018506092492893Pancreas: p = 8.5E-5
Whole Blood: p = 0.0055
Colon - Transverse: p = 0.00787
1468_2Cereal type: Biscuit cereal (e.g. Weetabix)UK Biobank (UKBB)Neale Lab2018533102465884Brain - Frontal Cortex (BA9): p = 0.0015
Colon - Sigmoid: p = 0.00321
Esophagus - Gastroesophageal Junction: p = 0.00321
1468_4Cereal type: MuesliUK Biobank (UKBB)Neale Lab2018615232383754Liver: p = 0.00481
Artery - Tibial: p = 0.00662
Colon - Sigmoid: p = 0.01
1468_5Cereal type: Other (e.g. Cornflakes, Frosties)UK Biobank (UKBB)Neale Lab2018581052417935Spleen: p = 9.64E-8
Lung: p = 4.23E-5
Brain - Putamen (basal ganglia): p = 3.49E-4
1508_2Coffee type: Instant coffeeUK Biobank (UKBB)Neale Lab20181583861250634Esophagus - Gastroesophageal Junction: p = 3.09E-4
Brain - Cortex: p = 0.00162
Brain - Anterior cingulate cortex (BA24): p = 0.00328
1508_1Coffee type: Decaffeinated coffee (any type)UK Biobank (UKBB)Neale Lab2018553102281393Pancreas: p = 0.02
Esophagus - Gastroesophageal Junction: p = 0.02
Esophagus - Muscularis: p = 0.02
1508_3Coffee type: Ground coffee (include espresso, filter etc)UK Biobank (UKBB)Neale Lab2018649622184874Brain - Anterior cingulate cortex (BA24): p = 5.86E-5
Brain - Frontal Cortex (BA9): p = 1.28E-4
Brain - Cortex: p = 2.72E-4
1508_4Coffee type: Other type of coffeeUK Biobank (UKBB)Neale Lab201847912786583Liver: p = 3.95E-4
Pancreas: p = 0.00219
Adrenal Gland: p = 0.02
1538_0Major dietary changes in the last 5 years: NoUK Biobank (UKBB)Neale Lab20182213681389264Colon - Sigmoid: p = 0.0021
Esophagus - Muscularis: p = 0.00521
Spleen: p = 0.00746
1538_1Major dietary changes in the last 5 years: Yes, because of illnessUK Biobank (UKBB)Neale Lab2018380513222435Spleen: p = 4.83E-5
Whole Blood: p = 4.83E-5
Uterus: p = 1.91E-4
1538_2Major dietary changes in the last 5 years: Yes, because of other reasonsUK Biobank (UKBB)Neale Lab20181008752594195Brain - Cerebellar Hemisphere: p = 5.8E-4
Brain - Cerebellum: p = 5.8E-4
Artery - Tibial: p = 9.72E-4
1618Alcohol usually taken with mealsUK Biobank (UKBB)Neale Lab2018125164595524Artery - Tibial: p = 0.00184
Brain - Cortex: p = 0.00754
Brain - Frontal Cortex (BA9): p = 0.00754
1677Breastfed as a babyUK Biobank (UKBB)Neale Lab2018193838799054Prostate: p = 3.62E-4
Brain - Cortex: p = 0.00204
Brain - Frontal Cortex (BA9): p = 0.00626
1707_1Handedness (chirality/laterality): Right-handedUK Biobank (UKBB)Neale Lab2018320242406714Brain - Cerebellar Hemisphere: p = 6.58E-4
Brain - Cerebellum: p = 0.0024
Brain - Amygdala: p = 0.00786
1707_2Handedness (chirality/laterality): Left-handedUK Biobank (UKBB)Neale Lab2018345853263284Brain - Cerebellar Hemisphere: p = 0.00215
Brain - Cerebellum: p = 0.00716
Brain - Anterior cingulate cortex (BA24): p = 0.02
1707_3Handedness (chirality/laterality): Use both right and left hands equallyUK Biobank (UKBB)Neale Lab201860863548273Esophagus - Mucosa: p = 0.00634
Nerve - Tibial: p = 0.01
Adrenal Gland: p = 0.03
1747_3Hair colour (natural, before greying): Light brownUK Biobank (UKBB)Neale Lab20181475602127105Colon - Sigmoid: p = 5.34E-5
Esophagus - Gastroesophageal Junction: p = 8.32E-5
Esophagus - Muscularis: p = 0.00139
1747_1Hair colour (natural, before greying): BlondeUK Biobank (UKBB)Neale Lab2018411783190924Skin - Sun Exposed (Lower leg): p = 1.76E-10
Skin - Not Sun Exposed (Suprapubic): p = 6.64E-10
Esophagus - Mucosa: p = 1.71E-4
1747_2Hair colour (natural, before greying): RedUK Biobank (UKBB)Neale Lab2018166153436555Kidney - Cortex: p = 0.00288
Testis: p = 0.00869
Esophagus - Gastroesophageal Junction: p = 0.0094
1747_4Hair colour (natural, before greying): Dark brownUK Biobank (UKBB)Neale Lab20181346272256434Skin - Sun Exposed (Lower leg): p = 8.8E-5
Skin - Not Sun Exposed (Suprapubic): p = 2.13E-4
Esophagus - Mucosa: p = 4.95E-4
1747_5Hair colour (natural, before greying): BlackUK Biobank (UKBB)Neale Lab2018158093444615Skin - Not Sun Exposed (Suprapubic): p = 4.1E-4
Skin - Sun Exposed (Lower leg): p = 4.1E-4
Esophagus - Muscularis: p = 0.00132
1747_6Hair colour (natural, before greying): OtherUK Biobank (UKBB)Neale Lab201844813557895Pituitary: p = 4.34E-4
Pancreas: p = 0.02
Spleen: p = 0.02
1767Adopted as a childUK Biobank (UKBB)Neale Lab201851583552923Breast - Mammary Tissue: p = 0.00239
Adipose - Subcutaneous: p = 0.00368
Pituitary: p = 0.00993
1777Part of a multiple birthUK Biobank (UKBB)Neale Lab201879193475483Kidney - Cortex: p = 5.23E-4
Thyroid: p = 0.00917
Minor Salivary Gland: p = 0.04
1787Maternal smoking around birthUK Biobank (UKBB)Neale Lab2018951822147604Colon - Sigmoid: p = 8.17E-5
Brain - Anterior cingulate cortex (BA24): p = 8.45E-5
Brain - Frontal Cortex (BA9): p = 8.45E-5
1797Father still aliveUK Biobank (UKBB)Neale Lab2018812292703094Skin - Sun Exposed (Lower leg): p = 0.00199
Adrenal Gland: p = 0.00287
Skin - Not Sun Exposed (Suprapubic): p = 0.01
1835Mother still aliveUK Biobank (UKBB)Neale Lab20181402462147834Adrenal Gland: p = 0.02
Liver: p = 0.02
Lung: p = 0.02
1920Mood swingsUK Biobank (UKBB)Neale Lab20181589821936224Brain - Caudate (basal ganglia): p = 1.01E-7
Brain - Putamen (basal ganglia): p = 2.15E-6
Brain - Substantia nigra: p = 2.15E-6
1930MiserablenessUK Biobank (UKBB)Neale Lab20181517522034304Brain - Frontal Cortex (BA9): p = 1.61E-7
Brain - Nucleus accumbens (basal ganglia): p = 3.08E-7
Brain - Substantia nigra: p = 1.08E-6
1940IrritabilityUK Biobank (UKBB)Neale Lab2018968622483694Brain - Substantia nigra: p = 3.06E-4
Brain - Frontal Cortex (BA9): p = 4.97E-4
Esophagus - Muscularis: p = 4.97E-4
1950Sensitivity / hurt feelingsUK Biobank (UKBB)Neale Lab20181947551560664Brain - Frontal Cortex (BA9): p = 6.96E-5
Brain - Cerebellar Hemisphere: p = 2.02E-4
Brain - Cerebellum: p = 2.02E-4
1960Fed-up feelingsUK Biobank (UKBB)Neale Lab20181433322104324Brain - Cortex: p = 8.46E-7
Brain - Nucleus accumbens (basal ganglia): p = 8.46E-7
Brain - Caudate (basal ganglia): p = 1.5E-6
1970Nervous feelingsUK Biobank (UKBB)Neale Lab2018831202687094Brain - Cortex: p = 1.69E-8
Brain - Cerebellum: p = 6.05E-8
Brain - Cerebellar Hemisphere: p = 2.07E-7
1980Worrier / anxious feelingsUK Biobank (UKBB)Neale Lab20181994631523704Brain - Nucleus accumbens (basal ganglia): p = 1.21E-10
Brain - Anterior cingulate cortex (BA24): p = 5.15E-10
Brain - Caudate (basal ganglia): p = 5.15E-10
1990Tense / 'highly strung'UK Biobank (UKBB)Neale Lab2018605132896464Brain - Cerebellar Hemisphere: p = 1.02E-4
Brain - Cerebellum: p = 1.7E-4
Brain - Frontal Cortex (BA9): p = 1.7E-4
2000Worry too long after embarrassmentUK Biobank (UKBB)Neale Lab20181653101812174Brain - Caudate (basal ganglia): p = 7.36E-8
Brain - Hypothalamus: p = 7.36E-8
Brain - Putamen (basal ganglia): p = 2.79E-7
2010Suffer from 'nerves'UK Biobank (UKBB)Neale Lab2018739382741444Brain - Frontal Cortex (BA9): p = 3.97E-5
Brain - Amygdala: p = 1.23E-4
Brain - Anterior cingulate cortex (BA24): p = 1.23E-4
2020Loneliness, isolationUK Biobank (UKBB)Neale Lab2018635082920755Brain - Nucleus accumbens (basal ganglia): p = 1.32E-5
Brain - Caudate (basal ganglia): p = 2.71E-4
Brain - Frontal Cortex (BA9): p = 4.02E-4
2030Guilty feelingsUK Biobank (UKBB)Neale Lab20181001282517794Brain - Hypothalamus: p = 3.83E-7
Brain - Amygdala: p = 7.5E-7
Brain - Caudate (basal ganglia): p = 7.5E-7
2040Risk takingUK Biobank (UKBB)Neale Lab2018905002580494Brain - Frontal Cortex (BA9): p = 7.36E-4
Brain - Anterior cingulate cortex (BA24): p = 0.0046
Brain - Hippocampus: p = 0.0046
2090Seen doctor (GP) for nerves, anxiety, tension or depressionUK Biobank (UKBB)Neale Lab20181235282351654Brain - Frontal Cortex (BA9): p = 3.82E-5
Brain - Substantia nigra: p = 3.82E-5
Brain - Cortex: p = 3.11E-4
2100Seen a psychiatrist for nerves, anxiety, tension or depressionUK Biobank (UKBB)Neale Lab2018412333183025Colon - Sigmoid: p = 4.1E-4
Spleen: p = 5.35E-4
Adrenal Gland: p = 0.00185
2129Answered sexual history questionsUK Biobank (UKBB)Neale Lab2018331404296115Muscle - Skeletal: p = 1.52E-4
Pituitary: p = 5.04E-4
Nerve - Tibial: p = 0.01
2159Ever had same-sex intercourseUK Biobank (UKBB)Neale Lab2018111093157403Brain - Frontal Cortex (BA9): p = 0.00436
Brain - Anterior cingulate cortex (BA24): p = 0.00646
Lung: p = 0.00716
2188Long-standing illness, disability or infirmityUK Biobank (UKBB)Neale Lab20181147982380004Lung: p = 2.3E-5
Whole Blood: p = 2.42E-4
Spleen: p = 3.18E-4
2207Wears glasses or contact lensesUK Biobank (UKBB)Neale Lab2018321768389094Esophagus - Gastroesophageal Junction: p = 2.35E-4
Esophagus - Muscularis: p = 0.00211
Small Intestine - Terminal Ileum: p = 0.00752
2227Other eye problemsUK Biobank (UKBB)Neale Lab2018517203084144Colon - Transverse: p = 0.00265
Colon - Sigmoid: p = 0.00518
Adrenal Gland: p = 0.00518
2247_0Hearing difficulty/problems: NoUK Biobank (UKBB)Neale Lab2018255838907974Artery - Tibial: p = 0.02
Thyroid: p = 0.02
Esophagus - Muscularis: p = 0.03
2247_1Hearing difficulty/problems: YesUK Biobank (UKBB)Neale Lab2018907102559254Thyroid: p = 0.0069
Esophagus - Muscularis: p = 0.01
Artery - Tibial: p = 0.02
2257Hearing difficulty/problems with background noiseUK Biobank (UKBB)Neale Lab20181341412198424Spleen: p = 7.86E-5
Uterus: p = 0.00142
Whole Blood: p = 0.00294
2316Wheeze or whistling in the chest in last yearUK Biobank (UKBB)Neale Lab2018738282806954Whole Blood: p = 8.19E-8
Lung: p = 1.11E-4
Spleen: p = 8.59E-4
2335Chest pain or discomfortUK Biobank (UKBB)Neale Lab2018562333012745Brain - Putamen (basal ganglia): p = 1.31E-5
Brain - Hippocampus: p = 3.92E-5
Brain - Amygdala: p = 1.12E-4
2345Ever had bowel cancer screeningUK Biobank (UKBB)Neale Lab20181144752408783Brain - Nucleus accumbens (basal ganglia): p = 0.00471
Brain - Anterior cingulate cortex (BA24): p = 0.0098
Stomach: p = 0.01
2365Ever had prostate specific antigen (PSA) testUK Biobank (UKBB)Neale Lab2018494591086494Colon - Transverse: p = 0.0042
Colon - Sigmoid: p = 0.04
Esophagus - Gastroesophageal Junction: p = 0.04
2395_1Hair/balding pattern: Pattern 1UK Biobank (UKBB)Neale Lab2018530761125734Vagina: p = 1.06E-9
Esophagus - Mucosa: p = 2.02E-5
Uterus: p = 1.29E-4
2395_2Hair/balding pattern: Pattern 2UK Biobank (UKBB)Neale Lab2018380441276055Vagina: p = 0.00242
Esophagus - Gastroesophageal Junction: p = 0.00512
Adipose - Subcutaneous: p = 0.00548
2395_3Hair/balding pattern: Pattern 3UK Biobank (UKBB)Neale Lab2018443041213455Adipose - Subcutaneous: p = 8.34E-5
Breast - Mammary Tissue: p = 3.17E-4
Artery - Tibial: p = 0.00259
2395_4Hair/balding pattern: Pattern 4UK Biobank (UKBB)Neale Lab2018302251354244Vagina: p = 2.85E-9
Adipose - Subcutaneous: p = 3.49E-5
Uterus: p = 1.46E-4
2415Had major operationsUK Biobank (UKBB)Neale Lab2018106506592313Artery - Tibial: p = 6.64E-4
Esophagus - Gastroesophageal Junction: p = 0.03
Esophagus - Muscularis: p = 0.03
2443Diabetes diagnosed by doctorUK Biobank (UKBB)Neale Lab2018172753429174Uterus: p = 8.83E-5
Lung: p = 1.31E-4
Artery - Aorta: p = 0.00205
2453Cancer diagnosed by doctorUK Biobank (UKBB)Neale Lab2018285093314724Artery - Coronary: p = 0.01
Small Intestine - Terminal Ileum: p = 0.01
Kidney - Cortex: p = 0.01
2463Fractured/broken bones in last 5 yearsUK Biobank (UKBB)Neale Lab2018347803244615Vagina: p = 2.02E-4
Artery - Aorta: p = 4.89E-4
Artery - Tibial: p = 7.47E-4
2473Other serious medical condition/disability diagnosed by doctorUK Biobank (UKBB)Neale Lab2018729652816235Spleen: p = 4.16E-5
Whole Blood: p = 1.91E-4
Brain - Cerebellum: p = 4.73E-4
2492Taking other prescription medicationsUK Biobank (UKBB)Neale Lab20181689931910344Spleen: p = 1.8E-8
Lung: p = 5.72E-5
Whole Blood: p = 1.76E-4
2644Light smokers, at least 100 smokes in lifetimeUK Biobank (UKBB)Neale Lab201844253527685Brain - Frontal Cortex (BA9): p = 0.00165
Brain - Anterior cingulate cortex (BA24): p = 0.00364
Brain - Cortex: p = 0.00364
2654_7Non-butter spread type details: Polyunsaturated/sunflower oil based spread (eg: Flora)UK Biobank (UKBB)Neale Lab2018643251257694Uterus: p = 0.00577
Vagina: p = 0.02
Colon - Sigmoid: p = 0.03
2654_2Non-butter spread type details: Flora Pro-Active or BenecolUK Biobank (UKBB)Neale Lab2018290481610464Liver: p = 1.69E-5
Small Intestine - Terminal Ileum: p = 0.02
Adrenal Gland: p = 0.03
2654_4Non-butter spread type details: Soft (tub) margarineUK Biobank (UKBB)Neale Lab2018236251664693Skin - Sun Exposed (Lower leg): p = 0.00104
Skin - Not Sun Exposed (Suprapubic): p = 0.00239
Brain - Putamen (basal ganglia): p = 0.0075
2654_5Non-butter spread type details: Hard (block) margarineUK Biobank (UKBB)Neale Lab20182211898733Pancreas: p = 0.01
Esophagus - Mucosa: p = 0.02
Minor Salivary Gland: p = 0.03
2654_6Non-butter spread type details: Olive oil based spread (eg: Bertolli)UK Biobank (UKBB)Neale Lab2018470301430643Brain - Cerebellar Hemisphere: p = 0.00943
Brain - Cerebellum: p = 0.00943
Brain - Substantia nigra: p = 0.01
2654_8Non-butter spread type details: Other low or reduced fat spreadUK Biobank (UKBB)Neale Lab2018190351710593Uterus: p = 0.00385
Colon - Sigmoid: p = 0.03
Spleen: p = 0.04
2654_9Non-butter spread type details: Other type of spread/margarineUK Biobank (UKBB)Neale Lab201868101832842Brain - Amygdala: p = 0.04
Adrenal Gland: p = 0.04
Esophagus - Gastroesophageal Junction: p = 0.06
2664_5Reason for reducing amount of alcohol drunk: Other reasonUK Biobank (UKBB)Neale Lab201870609634244Brain - Cerebellar Hemisphere: p = 7.4E-5
Brain - Cerebellum: p = 3.19E-4
Brain - Amygdala: p = 7.89E-4
2664_1Reason for reducing amount of alcohol drunk: Illness or ill healthUK Biobank (UKBB)Neale Lab201895121245213Spleen: p = 0.00855
Adipose - Subcutaneous: p = 0.009
Small Intestine - Terminal Ileum: p = 0.03
2664_2Reason for reducing amount of alcohol drunk: Doctor's adviceUK Biobank (UKBB)Neale Lab201829901310433Esophagus - Gastroesophageal Junction: p = 0.02
Esophagus - Muscularis: p = 0.05
Brain - Cortex: p = 0.06
2664_3Reason for reducing amount of alcohol drunk: Health precautionUK Biobank (UKBB)Neale Lab201843868901654Brain - Spinal cord (cervical c-1): p = 0.01
Colon - Transverse: p = 0.01
Liver: p = 0.02
2664_4Reason for reducing amount of alcohol drunk: Financial reasonsUK Biobank (UKBB)Neale Lab201870541269792Ovary: p = 0.00312
Artery - Coronary: p = 0.01
Nerve - Tibial: p = 0.02
2724Had menopauseUK Biobank (UKBB)Neale Lab2018119355438295Testis: p = 0.00285
Prostate: p = 0.00453
Spleen: p = 0.02
2814Ever used hormone-replacement therapy (HRT)UK Biobank (UKBB)Neale Lab2018761791174275Ovary: p = 0.00377
Uterus: p = 0.00821
Testis: p = 0.00917
2834Bilateral oophorectomy (both ovaries removed)UK Biobank (UKBB)Neale Lab2018156291758864Kidney - Cortex: p = 0.0013
Pancreas: p = 0.0046
Thyroid: p = 0.03
2844Had other major operationsUK Biobank (UKBB)Neale Lab2018129435630354Muscle - Skeletal: p = 1.79E-4
Brain - Cerebellar Hemisphere: p = 6.88E-4
Liver: p = 0.0071
2877_1Type of tobacco previously smoked: Manufactured cigarettesUK Biobank (UKBB)Neale Lab201879113101113Uterus: p = 1.69E-4
Vagina: p = 0.0043
Adipose - Subcutaneous: p = 0.00739
2877_2Type of tobacco previously smoked: Hand-rolled cigarettesUK Biobank (UKBB)Neale Lab20185978832463Whole Blood: p = 8.89E-4
Uterus: p = 0.00141
Artery - Coronary: p = 0.03
2877_3Type of tobacco previously smoked: Cigars or pipesUK Biobank (UKBB)Neale Lab20184133850912Artery - Coronary: p = 0.02
Pituitary: p = 0.02
Brain - Cortex: p = 0.04
2907Ever stopped smoking for 6+ monthsUK Biobank (UKBB)Neale Lab201837903500343Esophagus - Mucosa: p = 0.00376
Artery - Tibial: p = 0.02
Heart - Atrial Appendage: p = 0.02
2956General pain for 3+ monthsUK Biobank (UKBB)Neale Lab201845709033Pancreas: p = 0.03
Minor Salivary Gland: p = 0.06
Uterus: p = 0.06
2986Started insulin within one year diagnosis of diabetesUK Biobank (UKBB)Neale Lab20181999144165Spleen: p = 1.56E-7
Lung: p = 4.41E-5
Whole Blood: p = 8.74E-5
3005Fracture resulting from simple fallUK Biobank (UKBB)Neale Lab201820384139263Heart - Atrial Appendage: p = 0.00349
Stomach: p = 0.01
Colon - Transverse: p = 0.02
3079Pace-makerUK Biobank (UKBB)Neale Lab201811393597273Liver: p = 6.95E-4
Artery - Tibial: p = 0.03
Heart - Atrial Appendage: p = 0.04
3082Fractured heelUK Biobank (UKBB)Neale Lab20182380861403Esophagus - Gastroesophageal Junction: p = 0.01
Esophagus - Muscularis: p = 0.03
Skin - Not Sun Exposed (Suprapubic): p = 0.08
3089Caffeine drink within last hourUK Biobank (UKBB)Neale Lab201869243247013Heart - Atrial Appendage: p = 0.04
Vagina: p = 0.08
Brain - Amygdala: p = 0.11
3090Used an inhaler for chest within last hourUK Biobank (UKBB)Neale Lab201824243292013Whole Blood: p = 7.8E-5
Lung: p = 3.98E-4
Colon - Sigmoid: p = 0.03
3159Smoked cigarette or pipe within last hourUK Biobank (UKBB)Neale Lab20184238289723Adipose - Subcutaneous: p = 0.04
Whole Blood: p = 0.04
Nerve - Tibial: p = 0.04
3393Hearing aid userUK Biobank (UKBB)Neale Lab2018109422084163Brain - Cerebellum: p = 0.03
Heart - Atrial Appendage: p = 0.06
Thyroid: p = 0.06
3404Neck/shoulder pain for 3+ monthsUK Biobank (UKBB)Neale Lab201856156251203Liver: p = 0.01
Lung: p = 0.01
Adipose - Visceral (Omentum): p = 0.04
3414Hip pain for 3+ monthsUK Biobank (UKBB)Neale Lab20183130387583Stomach: p = 0.0046
Colon - Transverse: p = 0.00678
Kidney - Cortex: p = 0.02
3446_1Type of tobacco currently smoked: Manufactured cigarettesUK Biobank (UKBB)Neale Lab20181910384803Adrenal Gland: p = 0.0018
Whole Blood: p = 0.02
Kidney - Cortex: p = 0.05
3446_2Type of tobacco currently smoked: Hand-rolled cigarettesUK Biobank (UKBB)Neale Lab20186469211143Pituitary: p = 0.02
Adipose - Visceral (Omentum): p = 0.06
Brain - Cortex: p = 0.06
3446_3Type of tobacco currently smoked: Cigars or pipesUK Biobank (UKBB)Neale Lab20182011255723Liver: p = 0.00543
Brain - Frontal Cortex (BA9): p = 0.00727
Brain - Anterior cingulate cortex (BA24): p = 0.02
3571Back pain for 3+ monthsUK Biobank (UKBB)Neale Lab201862055285003Small Intestine - Terminal Ileum: p = 0.00451
Esophagus - Mucosa: p = 0.02
Vagina: p = 0.02
3591Ever had hysterectomy (womb removed)UK Biobank (UKBB)Neale Lab2018139731574404Artery - Tibial: p = 0.00443
Heart - Atrial Appendage: p = 0.00916
Colon - Sigmoid: p = 0.02
3606Chest pain or discomfort walking normallyUK Biobank (UKBB)Neale Lab20189617461203Brain - Amygdala: p = 0.00396
Brain - Spinal cord (cervical c-1): p = 0.00396
Brain - Caudate (basal ganglia): p = 0.00847
3616Chest pain due to walking ceases when standing stillUK Biobank (UKBB)Neale Lab20181644337792Brain - Frontal Cortex (BA9): p = 0.00146
Brain - Anterior cingulate cortex (BA24): p = 0.00379
Brain - Cortex: p = 0.00379
3731Former alcohol drinkerUK Biobank (UKBB)Neale Lab201812564111813Skin - Not Sun Exposed (Suprapubic): p = 0.00775
Small Intestine - Terminal Ileum: p = 0.00785
Muscle - Skeletal: p = 0.01
3741Stomach/abdominal pain for 3+ monthsUK Biobank (UKBB)Neale Lab201816580131673Thyroid: p = 8.47E-4
Prostate: p = 0.00766
Brain - Cerebellum: p = 0.02
3751Chest pain or discomfort when walking uphill or hurryingUK Biobank (UKBB)Neale Lab201811938329293Lung: p = 8.58E-4
Esophagus - Gastroesophageal Junction: p = 0.00551
Brain - Anterior cingulate cortex (BA24): p = 0.02
3773Knee pain for 3+ monthsUK Biobank (UKBB)Neale Lab201859814161863Nerve - Tibial: p = 0.00617
Ovary: p = 0.00843
Skin - Not Sun Exposed (Suprapubic): p = 0.04
3799Headaches for 3+ monthsUK Biobank (UKBB)Neale Lab201832075381063Artery - Aorta: p = 0.02
Liver: p = 0.02
Adrenal Gland: p = 0.02
3859_5Reason former drinker stopped drinking alcohol: Other reasonUK Biobank (UKBB)Neale Lab2018552865822Brain - Substantia nigra: p = 0.07
Muscle - Skeletal: p = 0.09
Esophagus - Gastroesophageal Junction: p = 0.15
3859_1Reason former drinker stopped drinking alcohol: Illness or ill healthUK Biobank (UKBB)Neale Lab2018317989312Nerve - Tibial: p = 0.01
Testis: p = 0.02
Colon - Sigmoid: p = 0.08
3859_2Reason former drinker stopped drinking alcohol: Doctor's adviceUK Biobank (UKBB)Neale Lab2018700114103Pituitary: p = 6.07E-4
Lung: p = 0.01
Spleen: p = 0.05
3859_3Reason former drinker stopped drinking alcohol: Health precautionUK Biobank (UKBB)Neale Lab2018247096402Thyroid: p = 0.00342
Vagina: p = 0.02
Brain - Hypothalamus: p = 0.03
3859_4Reason former drinker stopped drinking alcohol: Financial reasonsUK Biobank (UKBB)Neale Lab2018233118773Colon - Sigmoid: p = 0.01
Kidney - Cortex: p = 0.03
Minor Salivary Gland: p = 0.03
3912Adopted father still aliveUK Biobank (UKBB)Neale Lab201854429633Pancreas: p = 0.00421
Small Intestine - Terminal Ileum: p = 0.00941
Esophagus - Mucosa: p = 0.00993
3942Adopted mother still aliveUK Biobank (UKBB)Neale Lab2018107827342Brain - Anterior cingulate cortex (BA24): p = 0.02
Lung: p = 0.02
Brain - Amygdala: p = 0.02
4041Gestational diabetes onlyUK Biobank (UKBB)Neale Lab201869154283Artery - Coronary: p = 3.24E-4
Artery - Tibial: p = 3.24E-4
Muscle - Skeletal: p = 0.00135
4067Facial pains for 3+ monthsUK Biobank (UKBB)Neale Lab2018310734032Muscle - Skeletal: p = 0.10
Nerve - Tibial: p = 0.12
Colon - Transverse: p = 0.16
4291Number of attemptsUK Biobank (UKBB)Neale Lab201895738239914Lung: p = 0.0027
Pituitary: p = 0.00516
Spleen: p = 0.00662
4294_1Final attempt correct: yesUK Biobank (UKBB)Neale Lab201811500747223Skin - Sun Exposed (Lower leg): p = 6.33E-4
Skin - Not Sun Exposed (Suprapubic): p = 0.00256
Brain - Caudate (basal ganglia): p = 0.03
4294_0Final attempt correct: noUK Biobank (UKBB)Neale Lab201845811151483Skin - Sun Exposed (Lower leg): p = 0.00358
Brain - Caudate (basal ganglia): p = 0.00826
Brain - Putamen (basal ganglia): p = 0.00826
4294_9Final attempt correct: abandonUK Biobank (UKBB)Neale Lab20181411195882Brain - Cerebellum: p = 0.03
Liver: p = 0.03
Skin - Sun Exposed (Lower leg): p = 0.04
4501Non-accidental death in close genetic familyUK Biobank (UKBB)Neale Lab201831044826613Colon - Transverse: p = 0.00398
Liver: p = 0.01
Adipose - Subcutaneous: p = 0.02
4598Ever depressed for a whole weekUK Biobank (UKBB)Neale Lab201863119545865Kidney - Cortex: p = 0.00439
Colon - Sigmoid: p = 0.02
Prostate: p = 0.02
4631Ever unenthusiastic/disinterested for a whole weekUK Biobank (UKBB)Neale Lab201842374727715Brain - Cerebellar Hemisphere: p = 1.71E-4
Brain - Cerebellum: p = 1.71E-4
Whole Blood: p = 0.00151
4642Ever manic/hyper for 2 daysUK Biobank (UKBB)Neale Lab201865691105863Brain - Cerebellar Hemisphere: p = 5.28E-4
Heart - Atrial Appendage: p = 0.00122
Brain - Cerebellum: p = 0.00571
4653Ever highly irritable/argumentative for 2 daysUK Biobank (UKBB)Neale Lab201820930964294Skin - Not Sun Exposed (Suprapubic): p = 0.0013
Skin - Sun Exposed (Lower leg): p = 0.00265
Stomach: p = 0.00532
4717Shortness of breath walking on level groundUK Biobank (UKBB)Neale Lab2018124181055883Artery - Aorta: p = 0.00148
Colon - Sigmoid: p = 0.00668
Esophagus - Gastroesophageal Junction: p = 0.01
4728Leg pain on walkingUK Biobank (UKBB)Neale Lab201825997929085Stomach: p = 0.00812
Brain - Frontal Cortex (BA9): p = 0.02
Skin - Not Sun Exposed (Suprapubic): p = 0.03
4803_0Tinnitus: No, neverUK Biobank (UKBB)Neale Lab201883615342673Whole Blood: p = 2.03E-4
Pituitary: p = 0.0022
Brain - Cerebellar Hemisphere: p = 0.01
4803_11Tinnitus: Yes, now most or all of the timeUK Biobank (UKBB)Neale Lab201877391101433Esophagus - Muscularis: p = 0.00542
Esophagus - Gastroesophageal Junction: p = 0.00781
Uterus: p = 0.01
4803_12Tinnitus: Yes, now a lot of the timeUK Biobank (UKBB)Neale Lab201829591149233Ovary: p = 0.00398
Kidney - Cortex: p = 0.02
Pituitary: p = 0.03
4803_13Tinnitus: Yes, now some of the timeUK Biobank (UKBB)Neale Lab2018104891073933Pituitary: p = 0.0017
Uterus: p = 0.02
Brain - Cerebellar Hemisphere: p = 0.04
4803_14Tinnitus: Yes, but not now, but have in the pastUK Biobank (UKBB)Neale Lab2018130801048023Esophagus - Gastroesophageal Junction: p = 0.00843
Esophagus - Muscularis: p = 0.00843
Minor Salivary Gland: p = 0.01
4849_1Hearing test done: YesUK Biobank (UKBB)Neale Lab201811720526753Artery - Aorta: p = 0.03
Artery - Coronary: p = 0.03
Artery - Tibial: p = 0.06
4849_0Hearing test done: No, I am unable to do thisUK Biobank (UKBB)Neale Lab201813301185503Artery - Aorta: p = 0.00744
Artery - Coronary: p = 0.02
Artery - Tibial: p = 0.04
4849_11Hearing test done: I can only hear on the right sideUK Biobank (UKBB)Neale Lab20186981191823Brain - Anterior cingulate cortex (BA24): p = 0.04
Brain - Frontal Cortex (BA9): p = 0.04
Colon - Sigmoid: p = 0.04
4849_12Hearing test done: I can only hear on the left sideUK Biobank (UKBB)Neale Lab20186471192333Pancreas: p = 7.3E-6
Spleen: p = 9.28E-4
Thyroid: p = 0.01
4924Attempted fluid intelligence (FI) test.UK Biobank (UKBB)Neale Lab201811713115263Artery - Aorta: p = 3.38E-4
Artery - Coronary: p = 3.38E-4
Artery - Tibial: p = 3.38E-4
4935FI1 : numeric addition testUK Biobank (UKBB)Neale Lab201811196547582Skin - Sun Exposed (Lower leg): p = 0.01
Skin - Not Sun Exposed (Suprapubic): p = 0.02
Uterus: p = 0.03
4946FI2 : identify largest numberUK Biobank (UKBB)Neale Lab20181159199503Uterus: p = 8.73E-5
Artery - Aorta: p = 0.00453
Pancreas: p = 0.00824
4957FI3 : word interpolationUK Biobank (UKBB)Neale Lab201898753180624Brain - Caudate (basal ganglia): p = 2.49E-5
Brain - Hippocampus: p = 4.0E-5
Brain - Putamen (basal ganglia): p = 4.0E-5
4968FI4 : positional arithmeticUK Biobank (UKBB)Neale Lab201898344173465Artery - Aorta: p = 5.45E-4
Brain - Nucleus accumbens (basal ganglia): p = 0.00218
Brain - Cerebellar Hemisphere: p = 0.00266
4979FI5 : family relationship calculationUK Biobank (UKBB)Neale Lab201855922574343Esophagus - Muscularis: p = 0.02
Testis: p = 0.02
Muscle - Skeletal: p = 0.04
4990FI6 : conditional arithmeticUK Biobank (UKBB)Neale Lab201869944322375Brain - Cerebellar Hemisphere: p = 8.3E-5
Brain - Nucleus accumbens (basal ganglia): p = 8.3E-5
Brain - Cerebellum: p = 2.53E-4
5001FI7 : synonymUK Biobank (UKBB)Neale Lab201874026105344Artery - Aorta: p = 0.00871
Nerve - Tibial: p = 0.00871
Artery - Coronary: p = 0.02
5012FI8 : chained arithmeticUK Biobank (UKBB)Neale Lab201849086266065Heart - Atrial Appendage: p = 0.00924
Small Intestine - Terminal Ileum: p = 0.01
Prostate: p = 0.01
5181Ever had eye surgeryUK Biobank (UKBB)Neale Lab20185825740873Prostate: p = 0.00321
Skin - Not Sun Exposed (Suprapubic): p = 0.04
Skin - Sun Exposed (Lower leg): p = 0.04
5182_1Both eyes present: YesUK Biobank (UKBB)Neale Lab2018802831033Brain - Cortex: p = 3.63E-4
Brain - Caudate (basal ganglia): p = 6.23E-4
Brain - Hypothalamus: p = 0.00105
5183Current eye infectionUK Biobank (UKBB)Neale Lab2018838795483Artery - Aorta: p = 2.34E-4
Brain - Hypothalamus: p = 7.0E-4
Artery - Coronary: p = 0.00426
5324_0Ever had cataract surgery: NoUK Biobank (UKBB)Neale Lab2018413716623Brain - Hypothalamus: p = 0.00806
Brain - Substantia nigra: p = 0.00806
Brain - Amygdala: p = 0.02
5324_2Ever had cataract surgery: Right eye onlyUK Biobank (UKBB)Neale Lab201837954203Testis: p = 0.00825
Skin - Not Sun Exposed (Suprapubic): p = 0.02
Brain - Hypothalamus: p = 0.02
5324_3Ever had cataract surgery: Left eye onlyUK Biobank (UKBB)Neale Lab201830654933Heart - Atrial Appendage: p = 0.01
Vagina: p = 0.02
Colon - Sigmoid: p = 0.03
5324_4Ever had cataract surgery: Both eyesUK Biobank (UKBB)Neale Lab201897748223Colon - Transverse: p = 1.95E-4
Prostate: p = 5.74E-4
Esophagus - Gastroesophageal Junction: p = 0.01
5325_0Ever had refractive laser eye surgery: NoUK Biobank (UKBB)Neale Lab2018408516343Testis: p = 0.00352
Pancreas: p = 0.02
Stomach: p = 0.03
5325_2Ever had refractive laser eye surgery: Right eye onlyUK Biobank (UKBB)Neale Lab201820755123Esophagus - Mucosa: p = 0.01
Pancreas: p = 0.03
Kidney - Cortex: p = 0.11
5325_3Ever had refractive laser eye surgery: Left eye onlyUK Biobank (UKBB)Neale Lab201816955502Nerve - Tibial: p = 0.00333
Pituitary: p = 0.00522
Heart - Atrial Appendage: p = 0.05
5325_4Ever had refractive laser eye surgery: Both eyesUK Biobank (UKBB)Neale Lab2018125844613Nerve - Tibial: p = 0.02
Pancreas: p = 0.02
Whole Blood: p = 0.02
5327_0Ever had laser treatment for glaucoma or high eye pressure: NoUK Biobank (UKBB)Neale Lab201855971913Artery - Aorta: p = 0.00105
Artery - Tibial: p = 0.00176
Artery - Coronary: p = 0.00222
5327_4Ever had laser treatment for glaucoma or high eye pressure: Both eyesUK Biobank (UKBB)Neale Lab201813856503Artery - Tibial: p = 5.72E-4
Artery - Aorta: p = 0.00398
Artery - Coronary: p = 0.02
5328_0Ever had corneal graft surgery: NoUK Biobank (UKBB)Neale Lab201856441422Brain - Amygdala: p = 0.0089
Brain - Substantia nigra: p = 0.02
Brain - Nucleus accumbens (basal ganglia): p = 0.02
5452Leg pain when standing still or sittingUK Biobank (UKBB)Neale Lab20181600991483Liver: p = 0.02
Spleen: p = 0.02
Colon - Transverse: p = 0.06
5463Leg pain in calf/calvesUK Biobank (UKBB)Neale Lab20188462171053Esophagus - Gastroesophageal Junction: p = 0.00331
Esophagus - Muscularis: p = 0.02
Muscle - Skeletal: p = 0.02
5474Leg pain when walking uphill or hurryingUK Biobank (UKBB)Neale Lab20181725077473Vagina: p = 4.37E-5
Pituitary: p = 2.85E-4
Adipose - Visceral (Omentum): p = 0.00603
5485Leg pain when walking normallyUK Biobank (UKBB)Neale Lab201814312109933Esophagus - Muscularis: p = 0.04
Spleen: p = 0.11
Whole Blood: p = 0.18
5496Leg pain when walking ever disappears while walkingUK Biobank (UKBB)Neale Lab2018483890073Esophagus - Muscularis: p = 0.00438
Colon - Sigmoid: p = 0.00637
Colon - Transverse: p = 0.03
5518Leg pain on walking : effect of standing stillUK Biobank (UKBB)Neale Lab20188800136953Ovary: p = 0.05
Whole Blood: p = 0.05
Esophagus - Gastroesophageal Junction: p = 0.06
5529Surgery on leg arteries (other than for varicose veins)UK Biobank (UKBB)Neale Lab2018969249213Minor Salivary Gland: p = 6.09E-4
Esophagus - Mucosa: p = 0.0045
Vagina: p = 0.02
5540_0Surgery/amputation of toe or leg: NoUK Biobank (UKBB)Neale Lab2018256042873Testis: p = 0.01
Esophagus - Mucosa: p = 0.01
Ovary: p = 0.04
5540_1Surgery/amputation of toe or leg: Yes, toesUK Biobank (UKBB)Neale Lab2018149257423Heart - Left Ventricle: p = 0.02
Muscle - Skeletal: p = 0.02
Heart - Atrial Appendage: p = 0.03
5556FI9 : concept interpolationUK Biobank (UKBB)Neale Lab201819701154464Esophagus - Muscularis: p = 1.57E-5
Esophagus - Gastroesophageal Junction: p = 0.00166
Brain - Putamen (basal ganglia): p = 0.00246
5610_3Which eye(s) affected by presbyopia: Both eyesUK Biobank (UKBB)Neale Lab20182800934853Testis: p = 6.07E-4
Skin - Not Sun Exposed (Suprapubic): p = 0.00363
Skin - Sun Exposed (Lower leg): p = 0.00564
5610_1Which eye(s) affected by presbyopia: Right eyeUK Biobank (UKBB)Neale Lab20181735297593Skin - Sun Exposed (Lower leg): p = 0.00564
Brain - Substantia nigra: p = 0.03
Skin - Not Sun Exposed (Suprapubic): p = 0.03
5610_2Which eye(s) affected by presbyopia: Left eyeUK Biobank (UKBB)Neale Lab20181750297443Artery - Coronary: p = 0.00162
Skin - Sun Exposed (Lower leg): p = 0.01
Heart - Atrial Appendage: p = 0.02
5663Length of longest manic/irritable episodeUK Biobank (UKBB)Neale Lab20181538240922Kidney - Cortex: p = 2.07E-4
Pancreas: p = 0.00564
Pituitary: p = 0.04
5674Severity of manic/irritable episodesUK Biobank (UKBB)Neale Lab20181521657683Prostate: p = 0.00224
Minor Salivary Gland: p = 0.00288
Small Intestine - Terminal Ileum: p = 0.01
5699FI10 : arithmetic sequence recognitionUK Biobank (UKBB)Neale Lab20181672141593Esophagus - Gastroesophageal Junction: p = 0.0025
Lung: p = 0.01
Esophagus - Muscularis: p = 0.01
5779FI11 : antonymUK Biobank (UKBB)Neale Lab2018894335503Small Intestine - Terminal Ileum: p = 0.00202
Whole Blood: p = 0.02
Artery - Aorta: p = 0.03
5832_3Which eye(s) affected by hypermetropia (long sight): Both eyesUK Biobank (UKBB)Neale Lab20181290621843Thyroid: p = 0.00978
Muscle - Skeletal: p = 0.05
Uterus: p = 0.05
5832_1Which eye(s) affected by hypermetropia (long sight): Right eyeUK Biobank (UKBB)Neale Lab20181126139642Thyroid: p = 0.00365
Whole Blood: p = 0.00366
Esophagus - Gastroesophageal Junction: p = 0.03
5832_2Which eye(s) affected by hypermetropia (long sight): Left eyeUK Biobank (UKBB)Neale Lab20181058140323Lung: p = 0.00321
Pituitary: p = 0.02
Thyroid: p = 0.02
5843_3Which eye(s) affected by myopia (short sight): Both eyesUK Biobank (UKBB)Neale Lab20182618431333Whole Blood: p = 0.00205
Brain - Anterior cingulate cortex (BA24): p = 0.04
Stomach: p = 0.04
5843_1Which eye(s) affected by myopia (short sight): Right eyeUK Biobank (UKBB)Neale Lab20181607277103Heart - Left Ventricle: p = 0.00115
Heart - Atrial Appendage: p = 0.00189
Lung: p = 0.00511
5843_2Which eye(s) affected by myopia (short sight): Left eyeUK Biobank (UKBB)Neale Lab20181526277913Whole Blood: p = 0.00746
Stomach: p = 0.02
Brain - Cortex: p = 0.04
5855_3Which eye(s) affected by astigmatism: Both eyesUK Biobank (UKBB)Neale Lab2018670430452Adipose - Visceral (Omentum): p = 0.02
Stomach: p = 0.02
Lung: p = 0.04
5855_1Which eye(s) affected by astigmatism: Right eyeUK Biobank (UKBB)Neale Lab2018145182983Uterus: p = 0.01
Lung: p = 0.06
Muscle - Skeletal: p = 0.06
5855_2Which eye(s) affected by astigmatism: Left eyeUK Biobank (UKBB)Neale Lab2018159481553Liver: p = 0.01
Small Intestine - Terminal Ileum: p = 0.02
Skin - Not Sun Exposed (Suprapubic): p = 0.02
5866FI13 : subset inclusion logicUK Biobank (UKBB)Neale Lab201864723173Spleen: p = 4.5E-4
Prostate: p = 0.0027
Thyroid: p = 0.00956
5959Previously smoked cigarettes on most/all daysUK Biobank (UKBB)Neale Lab201813456603Brain - Hippocampus: p = 0.00609
Brain - Spinal cord (cervical c-1): p = 0.00609
Brain - Cortex: p = 0.00957
22642Usual length of each night shift during mixed shift periodsUK Biobank (UKBB)Neale Lab20180199983Pancreas: p = 0.01
Adrenal Gland: p = 0.02
Thyroid: p = 0.05
22645Rest days during mixed shift periodsUK Biobank (UKBB)Neale Lab20180172483Pituitary: p = 0.01
Thyroid: p = 0.01
Prostate: p = 0.03
24009Traffic intensity on the nearest roadUK Biobank (UKBB)Neale Lab201803560783Colon - Sigmoid: p = 0.02
Whole Blood: p = 0.03
Esophagus - Muscularis: p = 0.06
24013Total traffic load on major roadsUK Biobank (UKBB)Neale Lab201803560783Thyroid: p = 0.00511
Brain - Nucleus accumbens (basal ganglia): p = 0.02
Colon - Transverse: p = 0.02
24015Sum of road length of major roads within 100mUK Biobank (UKBB)Neale Lab201803560783Whole Blood: p = 0.01
Muscle - Skeletal: p = 0.02
Minor Salivary Gland: p = 0.02
30150Eosinophill countUK Biobank (UKBB)Neale Lab201803498562Whole Blood: p = 6.68E-20
Spleen: p = 5.45E-13
Small Intestine - Terminal Ileum: p = 2.49E-4
30160Basophill countUK Biobank (UKBB)Neale Lab201803498564Whole Blood: p = 5.05E-7
Spleen: p = 0.00216
Skin - Sun Exposed (Lower leg): p = 0.02
30170Nucleated red blood cell countUK Biobank (UKBB)Neale Lab201803498483Artery - Tibial: p = 0.00224
Breast - Mammary Tissue: p = 0.00393
Lung: p = 0.02
30230Nucleated red blood cell percentageUK Biobank (UKBB)Neale Lab201803498453Artery - Aorta: p = 0.00385
Artery - Coronary: p = 0.00385
Whole Blood: p = 0.00709
40009Reported occurrences of cancerUK Biobank (UKBB)Neale Lab20180586073Pituitary: p = 9.48E-4
Small Intestine - Terminal Ileum: p = 0.03
Thyroid: p = 0.03
22604_3Work hours - lumped category: 30 to 40 hoursUK Biobank (UKBB)Neale Lab201852138230393Brain - Substantia nigra: p = 0.00295
Brain - Cerebellar Hemisphere: p = 0.00658
Adrenal Gland: p = 0.00658
22604_4Work hours - lumped category: Over 40 hoursUK Biobank (UKBB)Neale Lab201837201379763Whole Blood: p = 0.0066
Thyroid: p = 0.00811
Adrenal Gland: p = 0.02
22604_2Work hours - lumped category: 20 to less-than-30 hoursUK Biobank (UKBB)Neale Lab201815156600213Artery - Tibial: p = 0.00294
Artery - Coronary: p = 0.00671
Artery - Aorta: p = 0.01
22604_1Work hours - lumped category: 15 to less-than-20 hoursUK Biobank (UKBB)Neale Lab201810086650913Colon - Transverse: p = 0.03
Brain - Hippocampus: p = 0.04
Brain - Amygdala: p = 0.07
22606_1Workplace very noisy: SometimesUK Biobank (UKBB)Neale Lab201851689390883Thyroid: p = 0.00107
Nerve - Tibial: p = 0.02
Pancreas: p = 0.02
22606_0Workplace very noisy: Rarely/neverUK Biobank (UKBB)Neale Lab201869515213823Brain - Nucleus accumbens (basal ganglia): p = 0.02
Prostate: p = 0.02
Brain - Caudate (basal ganglia): p = 0.03
22606_2Workplace very noisy: OftenUK Biobank (UKBB)Neale Lab201817469731843Brain - Cerebellar Hemisphere: p = 0.00149
Brain - Cerebellum: p = 0.00355
Brain - Substantia nigra: p = 0.01
22607_0Workplace very cold: Rarely/neverUK Biobank (UKBB)Neale Lab201877053136433Muscle - Skeletal: p = 0.00149
Heart - Atrial Appendage: p = 0.04
Heart - Left Ventricle: p = 0.04
22607_1Workplace very cold: SometimesUK Biobank (UKBB)Neale Lab201842823476773Pituitary: p = 0.00164
Vagina: p = 0.01
Uterus: p = 0.02
22607_2Workplace very cold: OftenUK Biobank (UKBB)Neale Lab20187881823073Colon - Transverse: p = 0.00219
Nerve - Tibial: p = 0.00224
Brain - Cerebellum: p = 0.02
22608_0Workplace very hot: Rarely/neverUK Biobank (UKBB)Neale Lab201868705219393Skin - Sun Exposed (Lower leg): p = 0.00924
Small Intestine - Terminal Ileum: p = 0.02
Brain - Cerebellum: p = 0.02
22608_1Workplace very hot: SometimesUK Biobank (UKBB)Neale Lab201852209383353Brain - Nucleus accumbens (basal ganglia): p = 0.00304
Brain - Putamen (basal ganglia): p = 0.00457
Muscle - Skeletal: p = 0.00812
22608_2Workplace very hot: OftenUK Biobank (UKBB)Neale Lab201810169799963Pituitary: p = 4.98E-4
Muscle - Skeletal: p = 0.00744
Thyroid: p = 0.01
22609_0Workplace very dusty: Rarely/neverUK Biobank (UKBB)Neale Lab20188146290813Heart - Atrial Appendage: p = 0.00263
Esophagus - Gastroesophageal Junction: p = 0.00914
Testis: p = 0.01
22609_2Workplace very dusty: OftenUK Biobank (UKBB)Neale Lab20189561800703Brain - Cerebellar Hemisphere: p = 8.25E-4
Brain - Cerebellum: p = 8.25E-4
Heart - Atrial Appendage: p = 0.00385
22609_1Workplace very dusty: SometimesUK Biobank (UKBB)Neale Lab201831586583793Adrenal Gland: p = 0.02
Brain - Cerebellar Hemisphere: p = 0.05
Brain - Cerebellum: p = 0.05
22610_0Workplace full of chemical or other fumes: Rarely/neverUK Biobank (UKBB)Neale Lab20188535849863Heart - Atrial Appendage: p = 0.01
Stomach: p = 0.01
Heart - Left Ventricle: p = 0.02
22610_1Workplace full of chemical or other fumes: SometimesUK Biobank (UKBB)Neale Lab201821709673513Skin - Sun Exposed (Lower leg): p = 0.00236
Skin - Not Sun Exposed (Suprapubic): p = 0.0056
Brain - Cerebellar Hemisphere: p = 0.00873
22610_2Workplace full of chemical or other fumes: OftenUK Biobank (UKBB)Neale Lab20185872828633Skin - Sun Exposed (Lower leg): p = 0.00454
Heart - Left Ventricle: p = 0.04
Muscle - Skeletal: p = 0.06
22611_0Workplace had a lot of cigarette smoke from other people smoking: Rarely/neverUK Biobank (UKBB)Neale Lab201877294134223Colon - Sigmoid: p = 0.00824
Heart - Atrial Appendage: p = 0.01
Muscle - Skeletal: p = 0.02
22611_1Workplace had a lot of cigarette smoke from other people smoking: SometimesUK Biobank (UKBB)Neale Lab201845053451153Brain - Substantia nigra: p = 0.00599
Colon - Transverse: p = 0.03
Brain - Spinal cord (cervical c-1): p = 0.03
22611_2Workplace had a lot of cigarette smoke from other people smoking: OftenUK Biobank (UKBB)Neale Lab201814941748623Brain - Cerebellar Hemisphere: p = 0.00312
Brain - Cerebellum: p = 0.00312
Brain - Cortex: p = 0.00312
22612_0Worked with materials containing asbestos: Rarely/neverUK Biobank (UKBB)Neale Lab20188350621622Colon - Sigmoid: p = 0.02
Brain - Spinal cord (cervical c-1): p = 0.05
Minor Salivary Gland: p = 0.05
22612_1Worked with materials containing asbestos: SometimesUK Biobank (UKBB)Neale Lab20188397689643Liver: p = 0.01
Heart - Atrial Appendage: p = 0.07
Ovary: p = 0.07
22612_2Worked with materials containing asbestos: OftenUK Biobank (UKBB)Neale Lab20181262751953Adrenal Gland: p = 0.00293
Nerve - Tibial: p = 0.01
Brain - Frontal Cortex (BA9): p = 0.03
22613_0Worked with paints, thinners or glues: Rarely/neverUK Biobank (UKBB)Neale Lab20188679635933Muscle - Skeletal: p = 0.03
Brain - Cortex: p = 0.05
Prostate: p = 0.06
22613_2Worked with paints, thinners or glues: OftenUK Biobank (UKBB)Neale Lab20183723849953Brain - Cortex: p = 0.00143
Brain - Frontal Cortex (BA9): p = 0.00143
Brain - Anterior cingulate cortex (BA24): p = 0.00732
22613_1Worked with paints, thinners or glues: SometimesUK Biobank (UKBB)Neale Lab201814095749083Brain - Cerebellum: p = 0.00607
Testis: p = 0.01
Brain - Cerebellar Hemisphere: p = 0.01
22614_0Worked with pesticides: Rarely/neverUK Biobank (UKBB)Neale Lab2018896115342Skin - Not Sun Exposed (Suprapubic): p = 0.00387
Skin - Sun Exposed (Lower leg): p = 0.01
Adipose - Visceral (Omentum): p = 0.02
22614_1Worked with pesticides: SometimesUK Biobank (UKBB)Neale Lab20183385847563Brain - Spinal cord (cervical c-1): p = 0.00321
Brain - Substantia nigra: p = 0.00846
Brain - Cerebellar Hemisphere: p = 0.01
22614_2Worked with pesticides: OftenUK Biobank (UKBB)Neale Lab2018524874953Pancreas: p = 0.02
Spleen: p = 0.05
Colon - Sigmoid: p = 0.07
22615_0Workplace had a lot of diesel exhaust: Rarely/neverUK Biobank (UKBB)Neale Lab20188769826783Liver: p = 0.03
Skin - Sun Exposed (Lower leg): p = 0.04
Minor Salivary Gland: p = 0.04
22615_1Workplace had a lot of diesel exhaust: SometimesUK Biobank (UKBB)Neale Lab201813038762723Artery - Aorta: p = 0.00966
Brain - Nucleus accumbens (basal ganglia): p = 0.02
Brain - Caudate (basal ganglia): p = 0.03
22615_2Workplace had a lot of diesel exhaust: OftenUK Biobank (UKBB)Neale Lab20183483856213Pituitary: p = 0.01
Muscle - Skeletal: p = 0.03
Esophagus - Mucosa: p = 0.06
22616_0Breathing problems during period of job: NoUK Biobank (UKBB)Neale Lab20188959115583Vagina: p = 5.0E-4
Esophagus - Mucosa: p = 0.00342
Minor Salivary Gland: p = 0.01
22616_1Breathing problems during period of job: YesUK Biobank (UKBB)Neale Lab20186697844523Adrenal Gland: p = 0.02
Vagina: p = 0.02
Lung: p = 0.03
22617_2315Job SOC coding: Primary and nursery education teaching professionalsUK Biobank (UKBB)Neale Lab20185625855242Adipose - Visceral (Omentum): p = 0.0069
Muscle - Skeletal: p = 0.0069
Heart - Left Ventricle: p = 0.04
22617_2451Job SOC coding: LibrariansUK Biobank (UKBB)Neale Lab20181248899013Artery - Coronary: p = 0.07
Artery - Tibial: p = 0.07
Nerve - Tibial: p = 0.07
22617_3113Job SOC coding: Engineering techniciansUK Biobank (UKBB)Neale Lab20181043901063Whole Blood: p = 0.04
Colon - Transverse: p = 0.07
Lung: p = 0.07
22617_1173Job SOC coding: Senior officers in fire, ambulance, prison and related servicesUK Biobank (UKBB)Neale Lab2018236909133Pancreas: p = 0.00957
Brain - Cerebellar Hemisphere: p = 0.02
Brain - Anterior cingulate cortex (BA24): p = 0.03
22617_4111Job SOC coding: Civil Service executive officersUK Biobank (UKBB)Neale Lab20183475876743Nerve - Tibial: p = 0.00114
Heart - Atrial Appendage: p = 0.00504
Esophagus - Muscularis: p = 0.02
22617_4215Job SOC coding: Personal assistants and other secretariesUK Biobank (UKBB)Neale Lab20185418857313Vagina: p = 0.00401
Whole Blood: p = 0.02
Brain - Cortex: p = 0.04
22617_2132Job SOC coding: Software professionalsUK Biobank (UKBB)Neale Lab20183519876303Kidney - Cortex: p = 0.00558
Pancreas: p = 0.00558
Adrenal Gland: p = 0.01
22617_3539Job SOC coding: Business and related associate professionals n.e.c.UK Biobank (UKBB)Neale Lab20181980891693Muscle - Skeletal: p = 5.72E-4
Brain - Amygdala: p = 0.04
Small Intestine - Terminal Ileum: p = 0.06
22617_2421Job SOC coding: Chartered and certified accountantsUK Biobank (UKBB)Neale Lab20181972891773Skin - Sun Exposed (Lower leg): p = 8.26E-5
Skin - Not Sun Exposed (Suprapubic): p = 1.06E-4
Liver: p = 0.00534
22617_5421Job SOC coding: Originators, compositors and print preparersUK Biobank (UKBB)Neale Lab2018184909652Adipose - Visceral (Omentum): p = 0.03
Liver: p = 0.03
Artery - Tibial: p = 0.04
22617_2121Job SOC coding: Civil engineersUK Biobank (UKBB)Neale Lab2018935902143Skin - Not Sun Exposed (Suprapubic): p = 0.00254
Skin - Sun Exposed (Lower leg): p = 0.00625
Pituitary: p = 0.02
22617_4123Job SOC coding: Counter clerksUK Biobank (UKBB)Neale Lab20183157879923Muscle - Skeletal: p = 0.00396
Small Intestine - Terminal Ileum: p = 0.00692
Adipose - Subcutaneous: p = 0.03
22617_4132Job SOC coding: Pensions and insurance clerksUK Biobank (UKBB)Neale Lab20181270898793Colon - Sigmoid: p = 0.00307
Prostate: p = 0.05
Heart - Left Ventricle: p = 0.10
22617_3533Job SOC coding: Insurance underwritersUK Biobank (UKBB)Neale Lab2018513906363Kidney - Cortex: p = 0.00359
Liver: p = 0.00359
Spleen: p = 0.04
22617_9119Job SOC coding: Fishing and agriculture related occupations n.e.c.UK Biobank (UKBB)Neale Lab2018182909673Testis: p = 0.00342
Ovary: p = 0.01
Muscle - Skeletal: p = 0.02
22617_5434Job SOC coding: Chefs, cooksUK Biobank (UKBB)Neale Lab2018806903433Pituitary: p = 0.00978
Kidney - Cortex: p = 0.03
Skin - Not Sun Exposed (Suprapubic): p = 0.03
22617_3119Job SOC coding: Science and engineering technicians n.e.c.UK Biobank (UKBB)Neale Lab20182018891313Nerve - Tibial: p = 0.00489
Kidney - Cortex: p = 0.03
Brain - Cortex: p = 0.04
22617_2211Job SOC coding: Medical practitionersUK Biobank (UKBB)Neale Lab20181500896493Artery - Coronary: p = 0.00741
Uterus: p = 0.00843
Artery - Tibial: p = 0.02
22617_2112Job SOC coding: Biological scientists and biochemistsUK Biobank (UKBB)Neale Lab20181067900823Vagina: p = 0.00349
Adipose - Subcutaneous: p = 0.04
Breast - Mammary Tissue: p = 0.07
22617_7111Job SOC coding: Sales and retail assistantsUK Biobank (UKBB)Neale Lab20184672864773Whole Blood: p = 0.00415
Ovary: p = 0.06
Uterus: p = 0.06
22617_2312Job SOC coding: Further education teaching professionalsUK Biobank (UKBB)Neale Lab20182520886293Colon - Transverse: p = 0.00593
Adrenal Gland: p = 0.02
Artery - Aorta: p = 0.04
22617_4150Job SOC coding: General office assistants/clerksUK Biobank (UKBB)Neale Lab20184022871273Brain - Cortex: p = 0.03
Uterus: p = 0.03
Pancreas: p = 0.06
22617_3211Job SOC coding: NursesUK Biobank (UKBB)Neale Lab20185062860873Adrenal Gland: p = 0.00528
Minor Salivary Gland: p = 0.02
Liver: p = 0.08
22617_9139Job SOC coding: Labourers in process and plant operations n.e.c.UK Biobank (UKBB)Neale Lab2018989901603Pituitary: p = 0.02
Esophagus - Mucosa: p = 0.04
Minor Salivary Gland: p = 0.04
22617_3543Job SOC coding: Marketing associate professionalsUK Biobank (UKBB)Neale Lab2018671904783Esophagus - Mucosa: p = 0.02
Heart - Left Ventricle: p = 0.03
Vagina: p = 0.08
22617_2314Job SOC coding: Secondary education teaching professionalsUK Biobank (UKBB)Neale Lab20187682834673Pituitary: p = 0.02
Muscle - Skeletal: p = 0.07
Heart - Left Ventricle: p = 0.10
22617_5231Job SOC coding: Motor mechanics, auto engineersUK Biobank (UKBB)Neale Lab2018779903703Breast - Mammary Tissue: p = 0.02
Esophagus - Gastroesophageal Junction: p = 0.04
Adipose - Subcutaneous: p = 0.07
22617_8137Job SOC coding: Sewing machinistsUK Biobank (UKBB)Neale Lab2018445907043Lung: p = 0.00219
Vagina: p = 0.00219
Liver: p = 0.00868
22617_3311Job SOC coding: NCOs and other ranksUK Biobank (UKBB)Neale Lab20182058890912Esophagus - Gastroesophageal Junction: p = 0.00162
Colon - Sigmoid: p = 0.0074
Esophagus - Muscularis: p = 0.00813
22617_5315Job SOC coding: Carpenters and joinersUK Biobank (UKBB)Neale Lab2018590905593Brain - Anterior cingulate cortex (BA24): p = 0.00259
Brain - Putamen (basal ganglia): p = 0.00441
Thyroid: p = 0.01
22617_6221Job SOC coding: Hairdressers, barbersUK Biobank (UKBB)Neale Lab2018427907222Vagina: p = 0.00868
Esophagus - Mucosa: p = 0.03
Spleen: p = 0.03
22617_3431Job SOC coding: Journalists, newspaper and periodical editorsUK Biobank (UKBB)Neale Lab2018507906423Adipose - Subcutaneous: p = 0.00484
Brain - Cortex: p = 0.00634
Heart - Left Ventricle: p = 0.01
22617_3221Job SOC coding: PhysiotherapistsUK Biobank (UKBB)Neale Lab2018485906643Prostate: p = 0.00862
Brain - Caudate (basal ganglia): p = 0.00874
Brain - Cerebellar Hemisphere: p = 0.00874
22617_9219Job SOC coding: Elementary office occupations n.e.c.UK Biobank (UKBB)Neale Lab20183340878093Adipose - Subcutaneous: p = 0.01
Heart - Atrial Appendage: p = 0.08
Brain - Cerebellar Hemisphere: p = 0.08
22617_3312Job SOC coding: Police officers (sergeant and below)UK Biobank (UKBB)Neale Lab20181168899813Muscle - Skeletal: p = 0.00929
Small Intestine - Terminal Ileum: p = 0.02
Brain - Cerebellar Hemisphere: p = 0.02
22617_2123Job SOC coding: Electrical engineersUK Biobank (UKBB)Neale Lab2018667904823Ovary: p = 0.00534
Uterus: p = 0.00534
Lung: p = 0.01
22617_7211Job SOC coding: Call centre agents/operatorsUK Biobank (UKBB)Neale Lab2018776903732Prostate: p = 0.00404
Vagina: p = 0.02
Stomach: p = 0.09
22617_3541Job SOC coding: Buyers and purchasing officersUK Biobank (UKBB)Neale Lab2018404907453Small Intestine - Terminal Ileum: p = 0.00119
Adrenal Gland: p = 0.00365
Artery - Aorta: p = 0.0071
22617_3132Job SOC coding: IT user support techniciansUK Biobank (UKBB)Neale Lab2018707904423Minor Salivary Gland: p = 0.00153
Prostate: p = 0.01
Heart - Left Ventricle: p = 0.03
22617_4217Job SOC coding: TypistsUK Biobank (UKBB)Neale Lab20183020881293Brain - Spinal cord (cervical c-1): p = 0.01
Spleen: p = 0.01
Colon - Sigmoid: p = 0.04
22617_2442Job SOC coding: Social workersUK Biobank (UKBB)Neale Lab20181509896403Stomach: p = 0.00264
Breast - Mammary Tissue: p = 0.00592
Adipose - Visceral (Omentum): p = 0.02
22617_5216Job SOC coding: Pipe fittersUK Biobank (UKBB)Neale Lab2018223909263Brain - Cerebellar Hemisphere: p = 0.02
Muscle - Skeletal: p = 0.04
Brain - Cerebellum: p = 0.04
22617_4113Job SOC coding: Local government clerical officers and assistantsUK Biobank (UKBB)Neale Lab20184823863262Artery - Coronary: p = 0.02
Colon - Transverse: p = 0.02
Artery - Aorta: p = 0.05
22617_1136Job SOC coding: Information and communication technology managersUK Biobank (UKBB)Neale Lab20181634895153Brain - Anterior cingulate cortex (BA24): p = 0.00246
Artery - Tibial: p = 0.00414
Brain - Amygdala: p = 0.01
22617_3534Job SOC coding: Finance and investment analysts/advisersUK Biobank (UKBB)Neale Lab2018868902813Brain - Spinal cord (cervical c-1): p = 0.00527
Adipose - Visceral (Omentum): p = 0.00874
Esophagus - Mucosa: p = 0.05
22617_2129Job SOC coding: Engineering professionals n.e.c.UK Biobank (UKBB)Neale Lab2018756903933Artery - Tibial: p = 0.00385
Esophagus - Gastroesophageal Junction: p = 0.01
Brain - Spinal cord (cervical c-1): p = 0.02
22617_3563Job SOC coding: Vocational and industrial trainers and instructorsUK Biobank (UKBB)Neale Lab20181015901343Kidney - Cortex: p = 8.46E-4
Pancreas: p = 0.01
Prostate: p = 0.01
22617_7125Job SOC coding: Merchandisers and window dressersUK Biobank (UKBB)Neale Lab2018192909573Whole Blood: p = 0.00414
Spleen: p = 0.00671
Small Intestine - Terminal Ileum: p = 0.01
22617_3422Job SOC coding: Product, clothing and related designersUK Biobank (UKBB)Neale Lab2018235909143Uterus: p = 9.19E-5
Brain - Spinal cord (cervical c-1): p = 3.77E-4
Ovary: p = 7.42E-4
22617_4122Job SOC coding: Accounts and wages clerks, book-keepers, other financial clerksUK Biobank (UKBB)Neale Lab20182752883973Colon - Sigmoid: p = 0.00622
Ovary: p = 0.00959
Esophagus - Muscularis: p = 0.02
22617_1151Job SOC coding: Financial institution managersUK Biobank (UKBB)Neale Lab20181320898292Breast - Mammary Tissue: p = 0.05
Adipose - Visceral (Omentum): p = 0.06
Liver: p = 0.06
22617_1234Job SOC coding: Shopkeepers and wholesale/retail dealersUK Biobank (UKBB)Neale Lab20181467896823Artery - Aorta: p = 0.00206
Artery - Coronary: p = 0.00543
Esophagus - Gastroesophageal Junction: p = 0.00543
22617_4216Job SOC coding: ReceptionistsUK Biobank (UKBB)Neale Lab20181407897423Colon - Transverse: p = 0.02
Nerve - Tibial: p = 0.02
Esophagus - Mucosa: p = 0.04
22617_6214Job SOC coding: Air travel assistantsUK Biobank (UKBB)Neale Lab2018354907953Pituitary: p = 0.00744
Muscle - Skeletal: p = 0.00993
Artery - Coronary: p = 0.04
22617_2321Job SOC coding: Scientific researchersUK Biobank (UKBB)Neale Lab20181190899593Thyroid: p = 7.64E-4
Brain - Caudate (basal ganglia): p = 0.02
Brain - Nucleus accumbens (basal ganglia): p = 0.02
22617_2411Job SOC coding: Solicitors and lawyers, judges and coronersUK Biobank (UKBB)Neale Lab20181088900613Colon - Transverse: p = 6.88E-5
Breast - Mammary Tissue: p = 0.00169
Pituitary: p = 0.00414
22617_1134Job SOC coding: Advertising and public relations managersUK Biobank (UKBB)Neale Lab2018608905413Ovary: p = 0.03
Heart - Atrial Appendage: p = 0.04
Pituitary: p = 0.04
22617_9233Job SOC coding: Cleaners, domesticsUK Biobank (UKBB)Neale Lab2018662904873Liver: p = 0.05
Heart - Atrial Appendage: p = 0.06
Heart - Left Ventricle: p = 0.14
22617_2111Job SOC coding: ChemistsUK Biobank (UKBB)Neale Lab20181080900693Colon - Sigmoid: p = 1.18E-4
Artery - Coronary: p = 6.78E-4
Artery - Tibial: p = 0.00801
22617_5223Job SOC coding: Metal working production and maintenance fittersUK Biobank (UKBB)Neale Lab20181208899413Brain - Hypothalamus: p = 0.00368
Brain - Amygdala: p = 0.00511
Brain - Substantia nigra: p = 0.00511
22617_2131Job SOC coding: IT strategy and planning professionalsUK Biobank (UKBB)Neale Lab20181863892863Liver: p = 0.00116
Brain - Spinal cord (cervical c-1): p = 0.00192
Adipose - Visceral (Omentum): p = 0.00678
22617_6139Job SOC coding: Animal care occupations n.e.c.UK Biobank (UKBB)Neale Lab2018158909913Artery - Coronary: p = 0.02
Adrenal Gland: p = 0.02
Breast - Mammary Tissue: p = 0.03
22617_6231Job SOC coding: Housekeepers and related occupationsUK Biobank (UKBB)Neale Lab2018323908262Small Intestine - Terminal Ileum: p = 0.00699
Colon - Transverse: p = 0.04
Skin - Sun Exposed (Lower leg): p = 0.05
22617_2434Job SOC coding: Chartered surveyors (not quantity surveyors)UK Biobank (UKBB)Neale Lab2018793903563Testis: p = 0.00721
Ovary: p = 0.01
Brain - Spinal cord (cervical c-1): p = 0.03
22617_4135Job SOC coding: Library assistants/clerksUK Biobank (UKBB)Neale Lab2018752903973Colon - Sigmoid: p = 0.00108
Breast - Mammary Tissue: p = 0.01
Esophagus - Gastroesophageal Junction: p = 0.02
22617_6123Job SOC coding: Playgroup leaders/assistantsUK Biobank (UKBB)Neale Lab2018459906902Testis: p = 0.02
Nerve - Tibial: p = 0.02
Brain - Substantia nigra: p = 0.03
22617_5241Job SOC coding: Electricians, electrical fittersUK Biobank (UKBB)Neale Lab20181061900882Brain - Caudate (basal ganglia): p = 0.00155
Brain - Putamen (basal ganglia): p = 0.00155
Brain - Hippocampus: p = 0.00414
22617_1231Job SOC coding: Property, housing and land managersUK Biobank (UKBB)Neale Lab2018348908013Brain - Caudate (basal ganglia): p = 0.03
Brain - Putamen (basal ganglia): p = 0.04
Minor Salivary Gland: p = 0.04
22617_2317Job SOC coding: Registrars and senior administrators of educational establishmentsUK Biobank (UKBB)Neale Lab20181447897022Small Intestine - Terminal Ileum: p = 0.03
Brain - Spinal cord (cervical c-1): p = 0.05
Brain - Caudate (basal ganglia): p = 0.06
22617_2423Job SOC coding: Management consultants, actuaries, economists and statisticiansUK Biobank (UKBB)Neale Lab20181070900793Pituitary: p = 0.00156
Thyroid: p = 0.00914
Prostate: p = 0.04
22617_4141Job SOC coding: TelephonistsUK Biobank (UKBB)Neale Lab2018660904893Adipose - Subcutaneous: p = 0.03
Artery - Aorta: p = 0.03
Nerve - Tibial: p = 0.04
22617_6111Job SOC coding: Nursing auxiliaries and assistantsUK Biobank (UKBB)Neale Lab20181301898483Adrenal Gland: p = 0.01
Brain - Cerebellar Hemisphere: p = 0.03
Brain - Cerebellum: p = 0.03
22617_3111Job SOC coding: Laboratory techniciansUK Biobank (UKBB)Neale Lab20182602885473Prostate: p = 0.01
Whole Blood: p = 0.05
Lung: p = 0.06
22617_3433Job SOC coding: Public relations officersUK Biobank (UKBB)Neale Lab2018517906323Adipose - Visceral (Omentum): p = 0.00252
Brain - Substantia nigra: p = 0.004
Lung: p = 0.00955
22617_3131Job SOC coding: IT operations techniciansUK Biobank (UKBB)Neale Lab20181102900473Colon - Transverse: p = 0.00496
Brain - Substantia nigra: p = 0.00849
Artery - Aorta: p = 0.01
22617_3413Job SOC coding: Actors, entertainersUK Biobank (UKBB)Neale Lab2018192909573Colon - Transverse: p = 5.15E-4
Esophagus - Muscularis: p = 0.00222
Small Intestine - Terminal Ileum: p = 0.00986
22617_4131Job SOC coding: Filing and other records assistants/clerksUK Biobank (UKBB)Neale Lab20181537896122Breast - Mammary Tissue: p = 0.02
Pituitary: p = 0.05
Thyroid: p = 0.06
22617_3217Job SOC coding: Pharmaceutical dispensersUK Biobank (UKBB)Neale Lab2018169909803Colon - Sigmoid: p = 0.0027
Esophagus - Gastroesophageal Junction: p = 0.00639
Esophagus - Muscularis: p = 0.01
22617_3411Job SOC coding: ArtistsUK Biobank (UKBB)Neale Lab2018191909583Adipose - Subcutaneous: p = 0.02
Breast - Mammary Tissue: p = 0.03
Stomach: p = 0.03
22617_1223Job SOC coding: Restaurant and catering managersUK Biobank (UKBB)Neale Lab2018570905793Brain - Hypothalamus: p = 0.02
Artery - Coronary: p = 0.05
Brain - Spinal cord (cervical c-1): p = 0.05
22617_2443Job SOC coding: Probation officersUK Biobank (UKBB)Neale Lab2018240909093Heart - Atrial Appendage: p = 0.00874
Artery - Tibial: p = 0.01
Spleen: p = 0.01
22617_4112Job SOC coding: Civil Service administrative officers and assistantsUK Biobank (UKBB)Neale Lab20184090870593Thyroid: p = 0.00671
Brain - Cerebellar Hemisphere: p = 0.00917
Brain - Cerebellum: p = 0.03
22617_2311Job SOC coding: Higher education teaching professionalsUK Biobank (UKBB)Neale Lab20183100880493Spleen: p = 2.79E-4
Artery - Tibial: p = 0.00183
Testis: p = 0.00352
22617_5111Job SOC coding: FarmersUK Biobank (UKBB)Neale Lab2018170909793Muscle - Skeletal: p = 0.00122
Skin - Not Sun Exposed (Suprapubic): p = 0.02
Adipose - Visceral (Omentum): p = 0.03
22617_3421Job SOC coding: Graphic designersUK Biobank (UKBB)Neale Lab2018320908293Muscle - Skeletal: p = 0.00255
Vagina: p = 0.00978
Adrenal Gland: p = 0.03
22617_7112Job SOC coding: Retail cashiers and check-out operatorsUK Biobank (UKBB)Neale Lab2018924902253Uterus: p = 2.7E-4
Liver: p = 0.00149
Ovary: p = 0.02
22617_9111Job SOC coding: Farm workersUK Biobank (UKBB)Neale Lab2018381907683Lung: p = 0.00636
Whole Blood: p = 0.01
Spleen: p = 0.03
22617_3112Job SOC coding: Electrical/electronics techniciansUK Biobank (UKBB)Neale Lab2018953901962Muscle - Skeletal: p = 0.01
Adipose - Subcutaneous: p = 0.02
Kidney - Cortex: p = 0.02
22617_8139Job SOC coding: Assemblers and routine operatives n.e.c.UK Biobank (UKBB)Neale Lab20181230899193Lung: p = 0.02
Colon - Sigmoid: p = 0.02
Skin - Sun Exposed (Lower leg): p = 0.02
22617_5221Job SOC coding: Metal machining setters and setter-operatorsUK Biobank (UKBB)Neale Lab2018316908333Whole Blood: p = 1.9E-5
Lung: p = 0.02
Brain - Hippocampus: p = 0.03
22617_2113Job SOC coding: Physicists, geologists and meteorologistsUK Biobank (UKBB)Neale Lab2018733904163Prostate: p = 0.03
Lung: p = 0.04
Pituitary: p = 0.05
22617_3532Job SOC coding: BrokersUK Biobank (UKBB)Neale Lab2018665904843Brain - Cortex: p = 0.00288
Brain - Amygdala: p = 0.02
Brain - Caudate (basal ganglia): p = 0.02
22617_6124Job SOC coding: Educational assistantsUK Biobank (UKBB)Neale Lab20182304888453Esophagus - Gastroesophageal Junction: p = 0.00451
Esophagus - Muscularis: p = 0.00451
Brain - Putamen (basal ganglia): p = 0.01
22617_2124Job SOC coding: Electronics engineersUK Biobank (UKBB)Neale Lab2018931902183Pancreas: p = 6.38E-5
Adrenal Gland: p = 0.00261
Stomach: p = 0.01
22617_3542Job SOC coding: Sales representativesUK Biobank (UKBB)Neale Lab20181142900073Artery - Coronary: p = 0.00194
Heart - Atrial Appendage: p = 0.00509
Pituitary: p = 0.00801
22617_6219Job SOC coding: Leisure and travel service occupations n.e.c.UK Biobank (UKBB)Neale Lab2018202909473Heart - Left Ventricle: p = 0.04
Brain - Cerebellar Hemisphere: p = 0.05
Brain - Cerebellum: p = 0.05
22617_2122Job SOC coding: Mechanical engineersUK Biobank (UKBB)Neale Lab20181595895543Nerve - Tibial: p = 0.00592
Prostate: p = 0.02
Brain - Amygdala: p = 0.03
22617_2316Job SOC coding: Special needs education teaching professionalsUK Biobank (UKBB)Neale Lab20181209899403Prostate: p = 0.01
Artery - Tibial: p = 0.02
Muscle - Skeletal: p = 0.02
22617_2422Job SOC coding: Management accountantsUK Biobank (UKBB)Neale Lab2018769903803Esophagus - Gastroesophageal Junction: p = 8.02E-4
Esophagus - Muscularis: p = 0.00367
Adipose - Subcutaneous: p = 0.00584
22617_1122Job SOC coding: Managers in constructionUK Biobank (UKBB)Neale Lab20181060900893Heart - Atrial Appendage: p = 0.00115
Heart - Left Ventricle: p = 0.00189
Muscle - Skeletal: p = 0.00599
22617_9134Job SOC coding: Packers, bottlers, canners, fillersUK Biobank (UKBB)Neale Lab2018565905843Muscle - Skeletal: p = 0.04
Liver: p = 0.05
Adrenal Gland: p = 0.07
22617_2128Job SOC coding: Planning and quality control engineersUK Biobank (UKBB)Neale Lab2018333908163Lung: p = 0.01
Skin - Sun Exposed (Lower leg): p = 0.01
Skin - Not Sun Exposed (Suprapubic): p = 0.02
22617_1161Job SOC coding: Transport and distribution managersUK Biobank (UKBB)Neale Lab2018507906423Heart - Atrial Appendage: p = 0.00914
Adrenal Gland: p = 0.03
Ovary: p = 0.03
22617_2329Job SOC coding: Researchers n.e.c.UK Biobank (UKBB)Neale Lab20181028901213Adipose - Visceral (Omentum): p = 0.03
Brain - Nucleus accumbens (basal ganglia): p = 0.05
Adrenal Gland: p = 0.05
22617_6113Job SOC coding: Dental nursesUK Biobank (UKBB)Neale Lab2018237909123Brain - Anterior cingulate cortex (BA24): p = 1.61E-4
Brain - Amygdala: p = 4.8E-4
Esophagus - Mucosa: p = 8.25E-4
22617_4121Job SOC coding: Credit controllersUK Biobank (UKBB)Neale Lab2018406907432Adipose - Subcutaneous: p = 0.05
Liver: p = 0.07
Adipose - Visceral (Omentum): p = 0.10
22617_5323Job SOC coding: Painters and decoratorsUK Biobank (UKBB)Neale Lab2018366907833Nerve - Tibial: p = 0.05
Brain - Hippocampus: p = 0.05
Heart - Left Ventricle: p = 0.05
22617_2432Job SOC coding: Town plannersUK Biobank (UKBB)Neale Lab2018221909283Brain - Spinal cord (cervical c-1): p = 0.06
Thyroid: p = 0.07
Brain - Hippocampus: p = 0.09
22617_5222Job SOC coding: Tool makers, tool fitters and markers-outUK Biobank (UKBB)Neale Lab2018310908393Pituitary: p = 0.04
Artery - Aorta: p = 0.04
Pancreas: p = 0.05
22617_1183Job SOC coding: Healthcare practice managersUK Biobank (UKBB)Neale Lab2018191909583Liver: p = 0.00286
Spleen: p = 0.0046
Brain - Cortex: p = 0.02
22617_3562Job SOC coding: Personnel and industrial relations officersUK Biobank (UKBB)Neale Lab20181446897033Brain - Frontal Cortex (BA9): p = 0.01
Brain - Cortex: p = 0.03
Esophagus - Mucosa: p = 0.06
22617_2444Job SOC coding: ClergyUK Biobank (UKBB)Neale Lab2018533906163Testis: p = 0.00845
Ovary: p = 0.02
Skin - Not Sun Exposed (Suprapubic): p = 0.02
22617_5244Job SOC coding: TV, video and audio engineersUK Biobank (UKBB)Neale Lab2018231909183Testis: p = 0.07
Liver: p = 0.12
Brain - Amygdala: p = 0.15
22617_3319Job SOC coding: Protective service associate professionals n.e.c.UK Biobank (UKBB)Neale Lab2018138910113Small Intestine - Terminal Ileum: p = 0.00712
Whole Blood: p = 0.02
Brain - Nucleus accumbens (basal ganglia): p = 0.05
22617_1163Job SOC coding: Retail and wholesale managersUK Biobank (UKBB)Neale Lab20181753893962Pituitary: p = 0.00233
Thyroid: p = 0.00299
Esophagus - Mucosa: p = 0.02
22617_8133Job SOC coding: Routine inspectors and testersUK Biobank (UKBB)Neale Lab2018400907493Nerve - Tibial: p = 0.00398
Muscle - Skeletal: p = 0.06
Adipose - Subcutaneous: p = 0.09
22617_1233Job SOC coding: Hairdressing and beauty salon managers and proprietorsUK Biobank (UKBB)Neale Lab2018270908792Adrenal Gland: p = 0.00912
Vagina: p = 0.04
Minor Salivary Gland: p = 0.06
22617_3222Job SOC coding: Occupational therapistsUK Biobank (UKBB)Neale Lab2018299908504Pituitary: p = 0.04
Adipose - Subcutaneous: p = 0.05
Esophagus - Mucosa: p = 0.05
22617_2433Job SOC coding: Quantity surveyorsUK Biobank (UKBB)Neale Lab2018430907193Whole Blood: p = 0.00398
Stomach: p = 0.02
Spleen: p = 0.02
22617_9225Job SOC coding: Bar staffUK Biobank (UKBB)Neale Lab2018607905423Esophagus - Muscularis: p = 0.00868
Artery - Coronary: p = 0.02
Artery - Aorta: p = 0.03
22617_3215Job SOC coding: ChiropodistsUK Biobank (UKBB)Neale Lab2018132910173Heart - Atrial Appendage: p = 3.91E-4
Thyroid: p = 0.00221
Adipose - Visceral (Omentum): p = 0.01
22617_2127Job SOC coding: Production and process engineersUK Biobank (UKBB)Neale Lab2018470906793Esophagus - Mucosa: p = 3.59E-4
Kidney - Cortex: p = 9.97E-4
Colon - Transverse: p = 0.0026
22617_4136Job SOC coding: Database assistants/clerksUK Biobank (UKBB)Neale Lab2018640905093Esophagus - Muscularis: p = 9.97E-4
Esophagus - Gastroesophageal Junction: p = 0.02
Heart - Left Ventricle: p = 0.02
22617_3442Job SOC coding: Sports coaches, instructors and officialsUK Biobank (UKBB)Neale Lab2018242909073Adipose - Visceral (Omentum): p = 0.08
Esophagus - Mucosa: p = 0.08
Minor Salivary Gland: p = 0.11
22617_7212Job SOC coding: Customer care occupationsUK Biobank (UKBB)Neale Lab20181683894662Esophagus - Gastroesophageal Junction: p = 0.03
Adipose - Visceral (Omentum): p = 0.03
Artery - Tibial: p = 0.05
22617_7129Job SOC coding: Sales related occupations n.e.c.UK Biobank (UKBB)Neale Lab20181078900713Liver: p = 0.00388
Colon - Transverse: p = 0.01
Artery - Coronary: p = 0.02
22617_5215Job SOC coding: Welding tradesUK Biobank (UKBB)Neale Lab2018266908833Liver: p = 0.00219
Stomach: p = 0.01
Esophagus - Mucosa: p = 0.02
22617_7121Job SOC coding: Collector salespersons and credit agentsUK Biobank (UKBB)Neale Lab2018831903182Pituitary: p = 0.00678
Esophagus - Mucosa: p = 0.01
Skin - Sun Exposed (Lower leg): p = 0.02
22617_6114Job SOC coding: Houseparents and residential wardensUK Biobank (UKBB)Neale Lab2018646905033Brain - Spinal cord (cervical c-1): p = 0.00842
Brain - Hippocampus: p = 0.03
Brain - Amygdala: p = 0.05
22617_8122Job SOC coding: Coal mine operativesUK Biobank (UKBB)Neale Lab2018280908693Uterus: p = 2.91E-5
Artery - Coronary: p = 5.71E-4
Artery - Aorta: p = 0.0027
22617_6122Job SOC coding: Childminders and related occupationsUK Biobank (UKBB)Neale Lab2018892902573Muscle - Skeletal: p = 0.0071
Testis: p = 0.01
Artery - Tibial: p = 0.01
22617_5249Job SOC coding: Electrical/electronics engineers n.e.c.UK Biobank (UKBB)Neale Lab2018546906033Esophagus - Mucosa: p = 0.02
Adrenal Gland: p = 0.03
Uterus: p = 0.03
22617_2441Job SOC coding: Public service administrative professionalsUK Biobank (UKBB)Neale Lab20181352897973Liver: p = 0.03
Pituitary: p = 0.04
Kidney - Cortex: p = 0.05
22617_5113Job SOC coding: Gardeners and groundsmen/groundswomenUK Biobank (UKBB)Neale Lab2018580905692Esophagus - Gastroesophageal Junction: p = 0.00607
Esophagus - Muscularis: p = 0.01
Vagina: p = 0.01
22617_6212Job SOC coding: Travel agentsUK Biobank (UKBB)Neale Lab2018402907473Esophagus - Mucosa: p = 0.00232
Minor Salivary Gland: p = 0.006
Kidney - Cortex: p = 0.01
22617_2216Job SOC coding: VeterinariansUK Biobank (UKBB)Neale Lab2018102910473Kidney - Cortex: p = 0.10
Adrenal Gland: p = 0.17
Prostate: p = 0.17
22617_3561Job SOC coding: Public service associate professionalsUK Biobank (UKBB)Neale Lab20183281878683Whole Blood: p = 0.00221
Liver: p = 0.01
Spleen: p = 0.07
22617_3531Job SOC coding: Estimators, valuers and assessorsUK Biobank (UKBB)Neale Lab2018467906822Brain - Amygdala: p = 0.09
Brain - Cortex: p = 0.09
Adrenal Gland: p = 0.09
22617_5314Job SOC coding: Plumbers, heating and ventilating engineersUK Biobank (UKBB)Neale Lab2018428907212Breast - Mammary Tissue: p = 0.01
Heart - Atrial Appendage: p = 0.04
Adipose - Visceral (Omentum): p = 0.06
22617_6115Job SOC coding: Care assistants and home carersUK Biobank (UKBB)Neale Lab20181172899772Brain - Cerebellum: p = 0.00496
Brain - Cerebellar Hemisphere: p = 0.00763
Uterus: p = 0.01
22617_8216Job SOC coding: Rail transport operativesUK Biobank (UKBB)Neale Lab2018172909773Prostate: p = 0.02
Colon - Transverse: p = 0.02
Nerve - Tibial: p = 0.03
22617_1141Job SOC coding: Quality assurance managersUK Biobank (UKBB)Neale Lab2018395907543Liver: p = 0.00135
Artery - Coronary: p = 0.00416
Artery - Tibial: p = 0.00968
22617_2214Job SOC coding: Ophthalmic opticiansUK Biobank (UKBB)Neale Lab2018107910423Spleen: p = 0.0078
Muscle - Skeletal: p = 0.03
Small Intestine - Terminal Ileum: p = 0.03
22617_2213Job SOC coding: Pharmacists/pharmacologistsUK Biobank (UKBB)Neale Lab2018410907393Brain - Substantia nigra: p = 0.02
Minor Salivary Gland: p = 0.02
Kidney - Cortex: p = 0.02
22617_2319Job SOC coding: Teaching professionals n.e.c.UK Biobank (UKBB)Neale Lab20181627895223Ovary: p = 0.01
Testis: p = 0.02
Breast - Mammary Tissue: p = 0.03
22617_1112Job SOC coding: Directors and chief executives of major organisationsUK Biobank (UKBB)Neale Lab20182789883603Skin - Not Sun Exposed (Suprapubic): p = 0.00325
Skin - Sun Exposed (Lower leg): p = 0.00325
Heart - Left Ventricle: p = 0.00968
22617_3432Job SOC coding: Broadcasting associate professionalsUK Biobank (UKBB)Neale Lab2018396907533Spleen: p = 0.00696
Lung: p = 0.00917
Muscle - Skeletal: p = 0.02
22617_2212Job SOC coding: PsychologistsUK Biobank (UKBB)Neale Lab2018284908652Testis: p = 2.77E-4
Spleen: p = 0.07
Brain - Cerebellum: p = 0.10
22617_2431Job SOC coding: ArchitectsUK Biobank (UKBB)Neale Lab2018773903763Stomach: p = 0.01
Kidney - Cortex: p = 0.01
Skin - Not Sun Exposed (Suprapubic): p = 0.01
22617_6121Job SOC coding: Nursery nursesUK Biobank (UKBB)Neale Lab2018322908272Colon - Sigmoid: p = 0.02
Spleen: p = 0.02
Esophagus - Muscularis: p = 0.06
22617_2126Job SOC coding: Design and development engineersUK Biobank (UKBB)Neale Lab2018606905433Vagina: p = 6.18E-4
Artery - Tibial: p = 0.00432
Lung: p = 0.02
22617_1225Job SOC coding: Leisure and sports managersUK Biobank (UKBB)Neale Lab2018358907913Brain - Cerebellar Hemisphere: p = 0.03
Brain - Cerebellum: p = 0.03
Muscle - Skeletal: p = 0.05
22617_8117Job SOC coding: Metal making and treating process operativesUK Biobank (UKBB)Neale Lab2018120910293Brain - Cerebellum: p = 0.00637
Esophagus - Gastroesophageal Junction: p = 0.00843
Brain - Cerebellar Hemisphere: p = 0.01
22617_3115Job SOC coding: Quality assurance techniciansUK Biobank (UKBB)Neale Lab2018354907953Testis: p = 0.03
Esophagus - Gastroesophageal Junction: p = 0.05
Esophagus - Muscularis: p = 0.13
22617_5213Job SOC coding: Sheet metal workersUK Biobank (UKBB)Neale Lab2018128910213Stomach: p = 0.00472
Uterus: p = 0.01
Esophagus - Mucosa: p = 0.04
22617_9223Job SOC coding: Kitchen and catering assistantsUK Biobank (UKBB)Neale Lab2018511906383Whole Blood: p = 0.0071
Esophagus - Gastroesophageal Junction: p = 0.01
Minor Salivary Gland: p = 0.03
22617_3231Job SOC coding: Youth and community workersUK Biobank (UKBB)Neale Lab20181062900873Artery - Coronary: p = 0.01
Heart - Atrial Appendage: p = 0.01
Esophagus - Gastroesophageal Junction: p = 0.06
22617_5414Job SOC coding: Tailors and dressmakersUK Biobank (UKBB)Neale Lab2018163909863Artery - Coronary: p = 0.02
Uterus: p = 0.02
Lung: p = 0.03
22617_1171Job SOC coding: Officers in armed forcesUK Biobank (UKBB)Neale Lab2018579905703Brain - Hypothalamus: p = 5.41E-4
Brain - Cerebellar Hemisphere: p = 0.00145
Brain - Cerebellum: p = 0.00145
22617_3218Job SOC coding: Medical and dental techniciansUK Biobank (UKBB)Neale Lab2018374907752Minor Salivary Gland: p = 0.00294
Liver: p = 0.04
Heart - Atrial Appendage: p = 0.07
22617_3537Job SOC coding: Financial and accounting techniciansUK Biobank (UKBB)Neale Lab20181526896233Esophagus - Gastroesophageal Junction: p = 0.00115
Esophagus - Muscularis: p = 0.00115
Whole Blood: p = 0.02
22617_1152Job SOC coding: Office managersUK Biobank (UKBB)Neale Lab20181121900283Minor Salivary Gland: p = 4.31E-5
Esophagus - Mucosa: p = 1.67E-4
Stomach: p = 0.00108
22617_8149Job SOC coding: Construction operatives n.e.c.UK Biobank (UKBB)Neale Lab2018372907772Skin - Not Sun Exposed (Suprapubic): p = 0.01
Skin - Sun Exposed (Lower leg): p = 0.01
Nerve - Tibial: p = 0.02
22617_3512Job SOC coding: Aircraft pilots and flight engineersUK Biobank (UKBB)Neale Lab2018116910332Esophagus - Gastroesophageal Junction: p = 0.00396
Esophagus - Muscularis: p = 0.00901
Spleen: p = 0.04
22617_3513Job SOC coding: Ship and hovercraft officersUK Biobank (UKBB)Neale Lab2018342908073Nerve - Tibial: p = 0.00562
Spleen: p = 0.01
Brain - Substantia nigra: p = 0.02
22617_5492Job SOC coding: Furniture makers, other craft woodworkersUK Biobank (UKBB)Neale Lab2018197909522Skin - Not Sun Exposed (Suprapubic): p = 5.51E-4
Skin - Sun Exposed (Lower leg): p = 9.59E-4
Brain - Spinal cord (cervical c-1): p = 0.00273
22617_2322Job SOC coding: Social science researchersUK Biobank (UKBB)Neale Lab2018471906783Artery - Tibial: p = 0.04
Pancreas: p = 0.04
Skin - Not Sun Exposed (Suprapubic): p = 0.04
22617_9226Job SOC coding: Leisure and theme park attendantsUK Biobank (UKBB)Neale Lab2018156909933Artery - Coronary: p = 0.00696
Lung: p = 0.00696
Pituitary: p = 0.00862
22617_8132Job SOC coding: Assemblers (vehicles and metal goods)UK Biobank (UKBB)Neale Lab2018539906103Whole Blood: p = 0.00935
Colon - Transverse: p = 0.01
Prostate: p = 0.01
22617_1221Job SOC coding: Hotel and accommodation managersUK Biobank (UKBB)Neale Lab2018402907473Adrenal Gland: p = 0.00853
Kidney - Cortex: p = 0.00853
Vagina: p = 0.03
22617_8131Job SOC coding: Assemblers (electrical products)UK Biobank (UKBB)Neale Lab2018424907253Kidney - Cortex: p = 0.02
Prostate: p = 0.02
Muscle - Skeletal: p = 0.03
22617_1137Job SOC coding: Research and development managersUK Biobank (UKBB)Neale Lab20181276898733Pituitary: p = 0.01
Skin - Sun Exposed (Lower leg): p = 0.02
Nerve - Tibial: p = 0.04
22617_3214Job SOC coding: Medical radiographersUK Biobank (UKBB)Neale Lab2018142910073Colon - Transverse: p = 7.24E-5
Prostate: p = 0.00122
Small Intestine - Terminal Ileum: p = 0.00197
22617_4114Job SOC coding: Officers of non-governmental organisationsUK Biobank (UKBB)Neale Lab20181579895703Esophagus - Gastroesophageal Junction: p = 0.01
Colon - Sigmoid: p = 0.03
Thyroid: p = 0.04
22617_4212Job SOC coding: Legal secretariesUK Biobank (UKBB)Neale Lab20181046901033Brain - Hypothalamus: p = 5.32E-4
Brain - Anterior cingulate cortex (BA24): p = 0.00433
Brain - Cerebellum: p = 0.00433
22617_8211Job SOC coding: Heavy goods vehicle driversUK Biobank (UKBB)Neale Lab2018701904483Breast - Mammary Tissue: p = 0.00494
Uterus: p = 0.02
Muscle - Skeletal: p = 0.03
22617_5214Job SOC coding: Metal plate workers, shipwrights, rivetersUK Biobank (UKBB)Neale Lab2018263908862Liver: p = 0.02
Adrenal Gland: p = 0.02
Skin - Not Sun Exposed (Suprapubic): p = 0.04
22617_1135Job SOC coding: Personnel, training and industrial relations managersUK Biobank (UKBB)Neale Lab20181169899803Esophagus - Mucosa: p = 0.00543
Breast - Mammary Tissue: p = 0.02
Artery - Coronary: p = 0.04
22617_4211Job SOC coding: Medical secretariesUK Biobank (UKBB)Neale Lab20181040901093Minor Salivary Gland: p = 0.01
Brain - Amygdala: p = 0.06
Colon - Sigmoid: p = 0.06
22617_9121Job SOC coding: Labourers in building and woodworking tradesUK Biobank (UKBB)Neale Lab2018540906093Colon - Transverse: p = 2.0E-5
Kidney - Cortex: p = 1.91E-4
Breast - Mammary Tissue: p = 0.00216
22617_7123Job SOC coding: Roundsmen/women and van salespersonsUK Biobank (UKBB)Neale Lab2018276908733Whole Blood: p = 8.47E-4
Pancreas: p = 0.02
Uterus: p = 0.04
22617_6232Job SOC coding: CaretakersUK Biobank (UKBB)Neale Lab2018289908603Muscle - Skeletal: p = 0.02
Pituitary: p = 0.03
Esophagus - Mucosa: p = 0.04
22617_3412Job SOC coding: Authors, writersUK Biobank (UKBB)Neale Lab2018313908363Spleen: p = 0.01
Brain - Cerebellum: p = 0.03
Prostate: p = 0.05
22617_1113Job SOC coding: Senior officials in local governmentUK Biobank (UKBB)Neale Lab20181277898723Artery - Coronary: p = 0.00186
Artery - Tibial: p = 0.01
Colon - Sigmoid: p = 0.01
22617_3122Job SOC coding: DraughtspersonsUK Biobank (UKBB)Neale Lab2018290908592Brain - Nucleus accumbens (basal ganglia): p = 0.00206
Brain - Caudate (basal ganglia): p = 0.01
Muscle - Skeletal: p = 0.01
22617_4213Job SOC coding: School secretariesUK Biobank (UKBB)Neale Lab20181242899073Lung: p = 0.03
Brain - Spinal cord (cervical c-1): p = 0.04
Heart - Atrial Appendage: p = 0.04
22617_2125Job SOC coding: Chemical engineersUK Biobank (UKBB)Neale Lab2018258908913Brain - Substantia nigra: p = 0.0027
Artery - Tibial: p = 0.08
Esophagus - Mucosa: p = 0.10
22617_3520Job SOC coding: Legal associate professionalsUK Biobank (UKBB)Neale Lab2018140910093Kidney - Cortex: p = 0.00326
Spleen: p = 0.03
Adipose - Subcutaneous: p = 0.04
22617_1111Job SOC coding: Senior officials in national governmentUK Biobank (UKBB)Neale Lab2018853902963Esophagus - Mucosa: p = 3.79E-4
Vagina: p = 0.00243
Adipose - Subcutaneous: p = 0.00414
22617_9224Job SOC coding: Waiters, waitressesUK Biobank (UKBB)Neale Lab2018502906473Pituitary: p = 0.01
Heart - Atrial Appendage: p = 0.04
Lung: p = 0.04
22617_3121Job SOC coding: Architectural technologists and town planning techniciansUK Biobank (UKBB)Neale Lab2018181909683Brain - Nucleus accumbens (basal ganglia): p = 0.02
Prostate: p = 0.02
Vagina: p = 0.02
22617_1132Job SOC coding: Marketing and sales managersUK Biobank (UKBB)Neale Lab20182249889002Adipose - Visceral (Omentum): p = 0.01
Brain - Spinal cord (cervical c-1): p = 0.03
Brain - Substantia nigra: p = 0.11
22617_9221Job SOC coding: Hospital portersUK Biobank (UKBB)Neale Lab2018129910202Whole Blood: p = 0.07
Ovary: p = 0.10
Stomach: p = 0.10
22617_1181Job SOC coding: Hospital and health service managersUK Biobank (UKBB)Neale Lab2018970901793Esophagus - Gastroesophageal Junction: p = 4.81E-4
Esophagus - Muscularis: p = 4.81E-4
Colon - Sigmoid: p = 8.03E-4
22617_3434Job SOC coding: Photographers and audio-visual equipment operatorsUK Biobank (UKBB)Neale Lab2018420907293Pituitary: p = 1.67E-4
Skin - Sun Exposed (Lower leg): p = 0.00606
Prostate: p = 0.01
22617_8212Job SOC coding: Van driversUK Biobank (UKBB)Neale Lab2018801903483Adipose - Subcutaneous: p = 2.91E-4
Vagina: p = 0.02
Thyroid: p = 0.02
22617_4133Job SOC coding: Stock control clerksUK Biobank (UKBB)Neale Lab2018313908362Lung: p = 0.00496
Kidney - Cortex: p = 0.03
Colon - Transverse: p = 0.04
22617_1114Job SOC coding: Senior officials of special interest organisationsUK Biobank (UKBB)Neale Lab20182125890242Thyroid: p = 0.02
Heart - Atrial Appendage: p = 0.05
Nerve - Tibial: p = 0.05
22617_5412Job SOC coding: UpholsterersUK Biobank (UKBB)Neale Lab2018107910423Heart - Left Ventricle: p = 0.00385
Colon - Sigmoid: p = 0.00737
Heart - Atrial Appendage: p = 0.00968
22617_5245Job SOC coding: Computer engineers, installation and maintenanceUK Biobank (UKBB)Neale Lab2018424907252Nerve - Tibial: p = 0.00168
Ovary: p = 0.00168
Vagina: p = 0.02
22617_3229Job SOC coding: Therapists n.e.c.UK Biobank (UKBB)Neale Lab2018884902653Small Intestine - Terminal Ileum: p = 4.67E-5
Colon - Transverse: p = 0.00119
Kidney - Cortex: p = 0.00119
22617_8113Job SOC coding: Textile process operativesUK Biobank (UKBB)Neale Lab2018259908903Adrenal Gland: p = 0.00299
Brain - Spinal cord (cervical c-1): p = 0.00981
Brain - Hippocampus: p = 0.03
22617_5242Job SOC coding: Telecommunications engineersUK Biobank (UKBB)Neale Lab2018394907553Colon - Sigmoid: p = 0.01
Thyroid: p = 0.02
Heart - Atrial Appendage: p = 0.08
22617_8134Job SOC coding: Weighers, graders, sortersUK Biobank (UKBB)Neale Lab2018163909863Brain - Hypothalamus: p = 0.00379
Esophagus - Gastroesophageal Junction: p = 0.00488
Brain - Amygdala: p = 0.00593
22617_8124Job SOC coding: Energy plant operativesUK Biobank (UKBB)Neale Lab2018101910482Brain - Spinal cord (cervical c-1): p = 0.00812
Brain - Anterior cingulate cortex (BA24): p = 0.01
Small Intestine - Terminal Ileum: p = 0.03
22617_9251Job SOC coding: Shelf fillersUK Biobank (UKBB)Neale Lab2018435907143Adrenal Gland: p = 0.04
Pancreas: p = 0.04
Breast - Mammary Tissue: p = 0.04
22617_8111Job SOC coding: Food, drink and tobacco process operativesUK Biobank (UKBB)Neale Lab2018247909022Vagina: p = 0.02
Esophagus - Gastroesophageal Junction: p = 0.03
Spleen: p = 0.06
22617_1172Job SOC coding: Police officers (inspectors and above)UK Biobank (UKBB)Neale Lab2018369907803Artery - Coronary: p = 0.00269
Prostate: p = 0.00567
Breast - Mammary Tissue: p = 0.01
22617_3416Job SOC coding: Arts officers, producers and directorsUK Biobank (UKBB)Neale Lab2018265908843Brain - Spinal cord (cervical c-1): p = 0.04
Skin - Not Sun Exposed (Suprapubic): p = 0.04
Kidney - Cortex: p = 0.06
22617_5499Job SOC coding: Hand craft occupations n.e.c.UK Biobank (UKBB)Neale Lab2018115910343Adrenal Gland: p = 0.03
Breast - Mammary Tissue: p = 0.04
Spleen: p = 0.05
22617_3223Job SOC coding: Speech and language therapistsUK Biobank (UKBB)Neale Lab2018152909973Brain - Cortex: p = 0.01
Vagina: p = 0.01
Adrenal Gland: p = 0.02
22617_9149Job SOC coding: Other goods handling and storage occupations n.e.c.UK Biobank (UKBB)Neale Lab20181279898703Skin - Not Sun Exposed (Suprapubic): p = 0.00171
Skin - Sun Exposed (Lower leg): p = 0.00171
Whole Blood: p = 0.02
22617_9132Job SOC coding: Industrial cleaning process occupationsUK Biobank (UKBB)Neale Lab2018213909362Muscle - Skeletal: p = 0.00225
Heart - Left Ventricle: p = 0.02
Uterus: p = 0.02
22617_5232Job SOC coding: Vehicle body builders and repairersUK Biobank (UKBB)Neale Lab2018143910063Whole Blood: p = 0.00637
Esophagus - Mucosa: p = 0.04
Vagina: p = 0.07
22617_5432Job SOC coding: Bakers, flour confectionersUK Biobank (UKBB)Neale Lab2018189909602Brain - Spinal cord (cervical c-1): p = 0.00705
Brain - Putamen (basal ganglia): p = 0.00907
Brain - Hypothalamus: p = 0.01
22617_5312Job SOC coding: Bricklayers, masonsUK Biobank (UKBB)Neale Lab2018157909923Skin - Not Sun Exposed (Suprapubic): p = 0.00599
Skin - Sun Exposed (Lower leg): p = 0.00708
Minor Salivary Gland: p = 0.02
22617_5422Job SOC coding: PrintersUK Biobank (UKBB)Neale Lab2018123910263Esophagus - Muscularis: p = 0.00936
Testis: p = 0.01
Thyroid: p = 0.02
22617_2215Job SOC coding: Dental practitionersUK Biobank (UKBB)Neale Lab2018291908583Spleen: p = 0.00371
Small Intestine - Terminal Ileum: p = 0.0089
Whole Blood: p = 0.01
22617_9222Job SOC coding: Hotel portersUK Biobank (UKBB)Neale Lab2018117910323Colon - Sigmoid: p = 0.01
Heart - Atrial Appendage: p = 0.02
Heart - Left Ventricle: p = 0.03
22617_5319Job SOC coding: Construction trades n.e.c.UK Biobank (UKBB)Neale Lab2018290908592Kidney - Cortex: p = 0.00238
Colon - Transverse: p = 0.00909
Colon - Sigmoid: p = 0.03
22617_3212Job SOC coding: MidwivesUK Biobank (UKBB)Neale Lab2018726904233Nerve - Tibial: p = 0.00696
Small Intestine - Terminal Ileum: p = 0.02
Thyroid: p = 0.02
22617_9211Job SOC coding: Postal workers, mail sorters, messengers, couriersUK Biobank (UKBB)Neale Lab2018662904873Vagina: p = 0.01
Brain - Amygdala: p = 0.07
Brain - Cerebellar Hemisphere: p = 0.07
22617_8229Job SOC coding: Mobile machine drivers and operatives n.e.c.UK Biobank (UKBB)Neale Lab2018106910433Muscle - Skeletal: p = 0.00968
Artery - Aorta: p = 0.02
Artery - Tibial: p = 0.02
22617_8125Job SOC coding: Metal working machine operativesUK Biobank (UKBB)Neale Lab2018135910143Colon - Transverse: p = 0.06
Esophagus - Muscularis: p = 0.06
Adrenal Gland: p = 0.08
22617_2313Job SOC coding: Education officers, school inspectorsUK Biobank (UKBB)Neale Lab20181080900693Adrenal Gland: p = 0.00213
Pituitary: p = 0.00321
Minor Salivary Gland: p = 0.00626
22617_4214Job SOC coding: Company secretariesUK Biobank (UKBB)Neale Lab2018174909753Esophagus - Gastroesophageal Junction: p = 0.04
Lung: p = 0.04
Testis: p = 0.04
22617_3114Job SOC coding: Building and civil engineering techniciansUK Biobank (UKBB)Neale Lab2018129910203Skin - Not Sun Exposed (Suprapubic): p = 0.00194
Nerve - Tibial: p = 0.00502
Vagina: p = 0.00502
22617_8138Job SOC coding: Routine laboratory testersUK Biobank (UKBB)Neale Lab2018226909233Muscle - Skeletal: p = 8.47E-4
Brain - Hypothalamus: p = 0.00192
Brain - Nucleus accumbens (basal ganglia): p = 0.00515
22617_3564Job SOC coding: Careers advisers and vocational guidance specialistsUK Biobank (UKBB)Neale Lab2018390907593Liver: p = 0.00543
Artery - Aorta: p = 0.00599
Artery - Coronary: p = 0.01
22617_9133Job SOC coding: Printing machine minders and assistantsUK Biobank (UKBB)Neale Lab2018123910263Liver: p = 0.00745
Whole Blood: p = 0.00745
Lung: p = 0.01
22617_8213Job SOC coding: Bus and coach driversUK Biobank (UKBB)Neale Lab2018457906923Minor Salivary Gland: p = 0.02
Brain - Amygdala: p = 0.03
Brain - Hippocampus: p = 0.03
22617_3544Job SOC coding: Estate agents, auctioneersUK Biobank (UKBB)Neale Lab2018288908613Brain - Cerebellar Hemisphere: p = 0.02
Brain - Cerebellum: p = 0.02
Stomach: p = 0.02
22617_1224Job SOC coding: Publicans and managers of licensed premisesUK Biobank (UKBB)Neale Lab2018421907283Adrenal Gland: p = 0.00426
Artery - Aorta: p = 0.02
Brain - Caudate (basal ganglia): p = 0.02
22617_3232Job SOC coding: Housing and welfare officersUK Biobank (UKBB)Neale Lab2018509906403Breast - Mammary Tissue: p = 8.33E-4
Adipose - Visceral (Omentum): p = 0.00236
Adipose - Subcutaneous: p = 0.01
22617_2452Job SOC coding: Archivists and curatorsUK Biobank (UKBB)Neale Lab2018283908662Colon - Transverse: p = 0.01
Stomach: p = 0.03
Minor Salivary Gland: p = 0.03
22617_4134Job SOC coding: Transport and distribution clerksUK Biobank (UKBB)Neale Lab2018440907093Adipose - Subcutaneous: p = 0.02
Brain - Anterior cingulate cortex (BA24): p = 0.03
Brain - Frontal Cortex (BA9): p = 0.03
22617_1142Job SOC coding: Customer care managersUK Biobank (UKBB)Neale Lab2018535906143Pancreas: p = 0.01
Artery - Aorta: p = 0.01
Artery - Tibial: p = 0.03
22617_9259Job SOC coding: Elementary sales occupations n.e.c.UK Biobank (UKBB)Neale Lab2018228909213Skin - Not Sun Exposed (Suprapubic): p = 0.00993
Skin - Sun Exposed (Lower leg): p = 0.00993
Uterus: p = 0.01
22617_1133Job SOC coding: Purchasing managersUK Biobank (UKBB)Neale Lab2018273908763Liver: p = 0.03
Small Intestine - Terminal Ileum: p = 0.03
Pituitary: p = 0.04
22617_3535Job SOC coding: Taxation expertsUK Biobank (UKBB)Neale Lab2018260908893Liver: p = 0.02
Brain - Spinal cord (cervical c-1): p = 0.02
Muscle - Skeletal: p = 0.02
22617_1184Job SOC coding: Social services managersUK Biobank (UKBB)Neale Lab2018746904032Artery - Aorta: p = 0.00862
Artery - Tibial: p = 0.00862
Brain - Anterior cingulate cortex (BA24): p = 0.04
22617_1211Job SOC coding: Farm managersUK Biobank (UKBB)Neale Lab2018169909802Stomach: p = 0.00586
Colon - Transverse: p = 0.01
Esophagus - Gastroesophageal Junction: p = 0.04
22617_5112Job SOC coding: Horticultural tradesUK Biobank (UKBB)Neale Lab2018154909953Esophagus - Mucosa: p = 0.00523
Vagina: p = 0.00799
Brain - Spinal cord (cervical c-1): p = 0.03
22617_4142Job SOC coding: Communication operatorsUK Biobank (UKBB)Neale Lab2018412907373Skin - Sun Exposed (Lower leg): p = 0.02
Adipose - Subcutaneous: p = 0.02
Adipose - Visceral (Omentum): p = 0.02
22617_1162Job SOC coding: Storage and warehouse managersUK Biobank (UKBB)Neale Lab2018186909633Esophagus - Mucosa: p = 0.00119
Vagina: p = 0.00119
Ovary: p = 0.0071
22617_2419Job SOC coding: Legal professionals n.e.c.UK Biobank (UKBB)Neale Lab2018176909733Thyroid: p = 0.04
Adipose - Subcutaneous: p = 0.05
Adipose - Visceral (Omentum): p = 0.05
22617_8116Job SOC coding: Plastics process operativesUK Biobank (UKBB)Neale Lab2018192909573Brain - Caudate (basal ganglia): p = 0.05
Brain - Nucleus accumbens (basal ganglia): p = 0.05
Colon - Sigmoid: p = 0.05
22617_1131Job SOC coding: Financial managers and chartered secretariesUK Biobank (UKBB)Neale Lab2018255908943Brain - Spinal cord (cervical c-1): p = 0.00966
Small Intestine - Terminal Ileum: p = 0.07
Adipose - Subcutaneous: p = 0.07
22617_1232Job SOC coding: Garage managers and proprietorsUK Biobank (UKBB)Neale Lab2018213909363Skin - Not Sun Exposed (Suprapubic): p = 0.00222
Skin - Sun Exposed (Lower leg): p = 0.00222
Adrenal Gland: p = 0.01
22617_6211Job SOC coding: Sports and leisure assistantsUK Biobank (UKBB)Neale Lab2018207909423Small Intestine - Terminal Ileum: p = 0.0054
Nerve - Tibial: p = 0.01
Muscle - Skeletal: p = 0.02
22617_3536Job SOC coding: Importers, exportersUK Biobank (UKBB)Neale Lab2018146910032Esophagus - Mucosa: p = 0.01
Whole Blood: p = 0.01
Artery - Aorta: p = 0.02
22617_8114Job SOC coding: Chemical and related process operativesUK Biobank (UKBB)Neale Lab2018160909893Breast - Mammary Tissue: p = 0.02
Spleen: p = 0.02
Colon - Sigmoid: p = 0.02
22617_3415Job SOC coding: MusiciansUK Biobank (UKBB)Neale Lab2018165909842Nerve - Tibial: p = 0.00626
Liver: p = 0.02
Adrenal Gland: p = 0.03
22617_6131Job SOC coding: Veterinary nurses and assistantsUK Biobank (UKBB)Neale Lab2018145910043Stomach: p = 0.00162
Brain - Frontal Cortex (BA9): p = 0.00974
Whole Blood: p = 0.02
22617_1185Job SOC coding: Residential and day care managersUK Biobank (UKBB)Neale Lab2018374907753Prostate: p = 4.22E-4
Ovary: p = 0.00984
Small Intestine - Terminal Ileum: p = 0.06
22617_3313Job SOC coding: Fire service officers (leading fire officer and below)UK Biobank (UKBB)Neale Lab2018197909523Thyroid: p = 0.0062
Kidney - Cortex: p = 0.05
Stomach: p = 0.06
22617_9244Job SOC coding: School mid-day assistantsUK Biobank (UKBB)Neale Lab2018183909663Esophagus - Mucosa: p = 0.0018
Skin - Sun Exposed (Lower leg): p = 0.00207
Skin - Not Sun Exposed (Suprapubic): p = 0.0078
22617_8214Job SOC coding: Taxi, cab drivers and chauffeursUK Biobank (UKBB)Neale Lab2018252908973Nerve - Tibial: p = 0.01
Artery - Coronary: p = 0.04
Artery - Tibial: p = 0.04
22617_3567Job SOC coding: Occupational hygienists and safety officers (health and safety)UK Biobank (UKBB)Neale Lab2018348908013Esophagus - Gastroesophageal Junction: p = 0.02
Ovary: p = 0.02
Uterus: p = 0.02
22617_8215Job SOC coding: Driving instructorsUK Biobank (UKBB)Neale Lab2018128910213Skin - Sun Exposed (Lower leg): p = 0.02
Esophagus - Gastroesophageal Junction: p = 0.05
Kidney - Cortex: p = 0.05
22617_9241Job SOC coding: Security guards and related occupationsUK Biobank (UKBB)Neale Lab2018300908493Adrenal Gland: p = 8.38E-5
Kidney - Cortex: p = 0.02
Liver: p = 0.02
22617_3213Job SOC coding: ParamedicsUK Biobank (UKBB)Neale Lab2018101910483Skin - Not Sun Exposed (Suprapubic): p = 0.00709
Skin - Sun Exposed (Lower leg): p = 0.00709
Colon - Sigmoid: p = 0.03
22617_9249Job SOC coding: Elementary security occupations n.e.c.UK Biobank (UKBB)Neale Lab2018151909983Liver: p = 6.39E-4
Pancreas: p = 0.00494
Kidney - Cortex: p = 0.00696
22617_6213Job SOC coding: Travel and tour guidesUK Biobank (UKBB)Neale Lab2018201909483Colon - Transverse: p = 0.00592
Lung: p = 0.01
Minor Salivary Gland: p = 0.04
22617_9229Job SOC coding: Elementary personal services occupations n.e.c.UK Biobank (UKBB)Neale Lab2018112910373Uterus: p = 0.01
Artery - Tibial: p = 0.05
Heart - Atrial Appendage: p = 0.05
22617_1226Job SOC coding: Travel agency managersUK Biobank (UKBB)Neale Lab2018176909733Brain - Hypothalamus: p = 0.00257
Liver: p = 0.00257
Pituitary: p = 0.00321
22617_1123Job SOC coding: Managers in mining and energyUK Biobank (UKBB)Neale Lab2018318908312Brain - Spinal cord (cervical c-1): p = 0.00352
Brain - Hypothalamus: p = 0.00446
Brain - Nucleus accumbens (basal ganglia): p = 0.00713
22617_3314Job SOC coding: Prison service officers (below principal officer)UK Biobank (UKBB)Neale Lab2018111910383Whole Blood: p = 7.47E-4
Brain - Cerebellum: p = 0.04
Thyroid: p = 0.04
22617_1222Job SOC coding: Conference and exhibition managersUK Biobank (UKBB)Neale Lab2018104910453Liver: p = 1.65E-4
Pancreas: p = 0.00262
Ovary: p = 0.0071
22618_0Breathing problems improved/stopped away from workplace or on holiday: NoUK Biobank (UKBB)Neale Lab20184382867673Lung: p = 0.00492
Esophagus - Mucosa: p = 0.01
Uterus: p = 0.01
22618_1Breathing problems improved/stopped away from workplace or on holiday: YesUK Biobank (UKBB)Neale Lab20182688884613Whole Blood: p = 0.02
Adipose - Visceral (Omentum): p = 0.03
Nerve - Tibial: p = 0.03
22619_0Breathing problems responsible for leaving job: NoUK Biobank (UKBB)Neale Lab20185412857373Lung: p = 8.51E-4
Artery - Coronary: p = 0.02
Adipose - Visceral (Omentum): p = 0.02
22619_1Breathing problems responsible for leaving job: YesUK Biobank (UKBB)Neale Lab2018412907373Small Intestine - Terminal Ileum: p = 0.00303
Colon - Sigmoid: p = 0.01
Muscle - Skeletal: p = 0.01
22620_0Job involved shift work: NoUK Biobank (UKBB)Neale Lab20188620649432Brain - Spinal cord (cervical c-1): p = 0.0014
Lung: p = 0.00374
Brain - Cerebellar Hemisphere: p = 0.02
22620_1Job involved shift work: YesUK Biobank (UKBB)Neale Lab201825698654513Brain - Spinal cord (cervical c-1): p = 0.02
Adrenal Gland: p = 0.02
Muscle - Skeletal: p = 0.04
22630_0Day shifts worked: Shift pattern was worked for some (but not all) of jobUK Biobank (UKBB)Neale Lab20181756239413Skin - Not Sun Exposed (Suprapubic): p = 0.00935
Skin - Sun Exposed (Lower leg): p = 0.02
Brain - Cerebellum: p = 0.03
22630_9Day shifts worked: This type of shift pattern was not worked during jobUK Biobank (UKBB)Neale Lab20182069050073Artery - Coronary: p = 0.01
Muscle - Skeletal: p = 0.02
Vagina: p = 0.04
22630_1Day shifts worked: Shift pattern was worked for whole of jobUK Biobank (UKBB)Neale Lab20186046196513Pituitary: p = 0.00124
Skin - Not Sun Exposed (Suprapubic): p = 0.01
Skin - Sun Exposed (Lower leg): p = 0.02
22640_0Mixture of day and night shifts worked: Shift pattern was worked for some (but not all) of jobUK Biobank (UKBB)Neale Lab20189229164682Liver: p = 0.01
Skin - Sun Exposed (Lower leg): p = 0.03
Brain - Cerebellum: p = 0.04
22640_1Mixture of day and night shifts worked: Shift pattern was worked for whole of jobUK Biobank (UKBB)Neale Lab201812718129793Uterus: p = 0.0068
Thyroid: p = 0.02
Artery - Aorta: p = 0.10
22640_9Mixture of day and night shifts worked: This type of shift pattern was not worked during jobUK Biobank (UKBB)Neale Lab20188764169333Vagina: p = 0.03
Artery - Aorta: p = 0.04
Kidney - Cortex: p = 0.04
22650_9Night shifts worked: This type of shift pattern was not worked during jobUK Biobank (UKBB)Neale Lab2018247809173Colon - Sigmoid: p = 0.01
Heart - Atrial Appendage: p = 0.03
Brain - Hippocampus: p = 0.04
22650_0Night shifts worked: Shift pattern was worked for some (but not all) of jobUK Biobank (UKBB)Neale Lab2018799248983Prostate: p = 0.00799
Adipose - Subcutaneous: p = 0.00824
Brain - Putamen (basal ganglia): p = 0.01
22650_1Night shifts worked: Shift pattern was worked for whole of jobUK Biobank (UKBB)Neale Lab20181314243833Small Intestine - Terminal Ileum: p = 0.00354
Nerve - Tibial: p = 0.01
Artery - Aorta: p = 0.07
22660_108Gap coding: RetiredUK Biobank (UKBB)Neale Lab201853542165773Brain - Substantia nigra: p = 6.91E-4
Brain - Caudate (basal ganglia): p = 0.00116
Brain - Putamen (basal ganglia): p = 0.00116
22660_103Gap coding: Full-time or part-time educationUK Biobank (UKBB)Neale Lab201812489564103Adipose - Visceral (Omentum): p = 0.03
Artery - Tibial: p = 0.03
Colon - Transverse: p = 0.03
22660_105Gap coding: Looking after the home and/or familyUK Biobank (UKBB)Neale Lab201824577447933Minor Salivary Gland: p = 6.35E-4
Thyroid: p = 0.00158
Lung: p = 0.00835
22660_101Gap coding: Paid work for less than 15 hours per week on average or lasting less than 6 monthsUK Biobank (UKBB)Neale Lab201815086536653Uterus: p = 6.19E-4
Artery - Aorta: p = 0.02
Kidney - Cortex: p = 0.02
22660_102Gap coding: Unpaid or voluntary workUK Biobank (UKBB)Neale Lab20182521654352Muscle - Skeletal: p = 0.02
Heart - Left Ventricle: p = 0.05
Brain - Spinal cord (cervical c-1): p = 0.06
22660_106Gap coding: Unable to work due to sickness or disabilityUK Biobank (UKBB)Neale Lab20182028658642Adrenal Gland: p = 0.00404
Ovary: p = 0.02
Liver: p = 0.05
22660_107Gap coding: UnemployedUK Biobank (UKBB)Neale Lab20183610644323Pituitary: p = 1.71E-4
Prostate: p = 0.00103
Liver: p = 0.02
24014Close to major roadUK Biobank (UKBB)Neale Lab2018245563315223Adipose - Visceral (Omentum): p = 3.16E-4
Testis: p = 0.06
Brain - Putamen (basal ganglia): p = 0.09
40001_C349Underlying (primary) cause of death: ICD10: C34.9 Bronchus or lung, unspecifiedUK Biobank (UKBB)Neale Lab2018110079923Heart - Atrial Appendage: p = 0.00421
Adipose - Subcutaneous: p = 0.02
Heart - Left Ventricle: p = 0.02
40001_C159Underlying (primary) cause of death: ICD10: C15.9 Oesophagus, unspecifiedUK Biobank (UKBB)Neale Lab201829687963Brain - Cortex: p = 0.0031
Brain - Frontal Cortex (BA9): p = 0.01
Brain - Amygdala: p = 0.04
40001_C169Underlying (primary) cause of death: ICD10: C16.9 Stomach, unspecifiedUK Biobank (UKBB)Neale Lab201812589673Artery - Tibial: p = 0.01
Brain - Spinal cord (cervical c-1): p = 0.02
Nerve - Tibial: p = 0.02
40001_C189Underlying (primary) cause of death: ICD10: C18.9 Colon, unspecifiedUK Biobank (UKBB)Neale Lab201824388492Minor Salivary Gland: p = 0.00803
Artery - Coronary: p = 0.04
Skin - Sun Exposed (Lower leg): p = 0.06
40001_C19Underlying (primary) cause of death: ICD10: C19 Malignant neoplasm of rectosigmoid junctionUK Biobank (UKBB)Neale Lab201811889743Brain - Cerebellum: p = 0.01
Brain - Cerebellar Hemisphere: p = 0.02
Muscle - Skeletal: p = 0.04
40001_C20Underlying (primary) cause of death: ICD10: C20 Malignant neoplasm of rectumUK Biobank (UKBB)Neale Lab201812489682Nerve - Tibial: p = 0.00571
Heart - Left Ventricle: p = 0.00905
Heart - Atrial Appendage: p = 0.01
40001_C221Underlying (primary) cause of death: ICD10: C22.1 Intrahepatic bile duct carcinomaUK Biobank (UKBB)Neale Lab201812289702Adipose - Subcutaneous: p = 0.00397
Breast - Mammary Tissue: p = 0.01
Adipose - Visceral (Omentum): p = 0.02
40001_C259Underlying (primary) cause of death: ICD10: C25.9 Pancreas, unspecifiedUK Biobank (UKBB)Neale Lab201839686962Spleen: p = 0.00867
Colon - Transverse: p = 0.00968
Lung: p = 0.02
40001_C439Underlying (primary) cause of death: ICD10: C43.9 Malignant melanoma of skin, unspecifiedUK Biobank (UKBB)Neale Lab201811689763Esophagus - Gastroesophageal Junction: p = 0.00866
Adipose - Subcutaneous: p = 0.01
Esophagus - Muscularis: p = 0.02
40001_C459Underlying (primary) cause of death: ICD10: C45.9 Mesothelioma, unspecifiedUK Biobank (UKBB)Neale Lab201810989833Kidney - Cortex: p = 1.18E-4
Spleen: p = 0.00119
Pituitary: p = 0.00762
40001_C509Underlying (primary) cause of death: ICD10: C50.9 Breast, unspecifiedUK Biobank (UKBB)Neale Lab201851185813Pancreas: p = 0.00222
Pituitary: p = 0.02
Small Intestine - Terminal Ileum: p = 0.03
40001_C56Underlying (primary) cause of death: ICD10: C56 Malignant neoplasm of ovaryUK Biobank (UKBB)Neale Lab201822688663Colon - Sigmoid: p = 6.88E-4
Colon - Transverse: p = 0.00398
Artery - Aorta: p = 0.00952
40001_C64Underlying (primary) cause of death: ICD10: C64 Malignant neoplasm of kidney, except renal pelvisUK Biobank (UKBB)Neale Lab201817889143Pituitary: p = 0.00745
Esophagus - Mucosa: p = 0.01
Liver: p = 0.03
40001_C679Underlying (primary) cause of death: ICD10: C67.9 Bladder, unspecifiedUK Biobank (UKBB)Neale Lab201811589773Prostate: p = 0.00199
Stomach: p = 0.00579
Minor Salivary Gland: p = 0.02
40001_C719Underlying (primary) cause of death: ICD10: C71.9 Brain, unspecifiedUK Biobank (UKBB)Neale Lab201827088223Artery - Tibial: p = 0.00577
Artery - Coronary: p = 0.02
Colon - Sigmoid: p = 0.03
40001_C80Underlying (primary) cause of death: ICD10: C80 Malignant neoplasm without specification of siteUK Biobank (UKBB)Neale Lab201817989133Colon - Sigmoid: p = 0.02
Heart - Atrial Appendage: p = 0.02
Prostate: p = 0.02
40001_C900Underlying (primary) cause of death: ICD10: C90.0 Multiple myelomaUK Biobank (UKBB)Neale Lab201810489883Whole Blood: p = 0.00874
Nerve - Tibial: p = 0.03
Spleen: p = 0.03
40001_C920Underlying (primary) cause of death: ICD10: C92.0 Acute myeloid leukaemiaUK Biobank (UKBB)Neale Lab201811389793Kidney - Cortex: p = 4.04E-4
Small Intestine - Terminal Ileum: p = 0.00186
Adipose - Subcutaneous: p = 0.00591
40001_G122Underlying (primary) cause of death: ICD10: G12.2 Motor neuron diseaseUK Biobank (UKBB)Neale Lab201812289702Brain - Cerebellar Hemisphere: p = 4.12E-5
Brain - Cerebellum: p = 1.36E-4
Prostate: p = 1.36E-4
40001_I219Underlying (primary) cause of death: ICD10: I21.9 Acute myocardial infarction, unspecifiedUK Biobank (UKBB)Neale Lab201848386092Skin - Sun Exposed (Lower leg): p = 0.00496
Uterus: p = 0.0078
Skin - Not Sun Exposed (Suprapubic): p = 0.00914
40001_I251Underlying (primary) cause of death: ICD10: I25.1 Atherosclerotic heart diseaseUK Biobank (UKBB)Neale Lab201835687363Ovary: p = 0.00835
Brain - Caudate (basal ganglia): p = 0.03
Brain - Cerebellar Hemisphere: p = 0.03
40001_I259Underlying (primary) cause of death: ICD10: I25.9 Chronic ischaemic heart disease, unspecifiedUK Biobank (UKBB)Neale Lab201832887642Esophagus - Gastroesophageal Junction: p = 0.04
Heart - Left Ventricle: p = 0.05
Uterus: p = 0.06
40001_I64Underlying (primary) cause of death: ICD10: I64 Stroke, not specified as haemorrhage or infarctionUK Biobank (UKBB)Neale Lab201810389893Heart - Atrial Appendage: p = 0.00365
Brain - Cerebellar Hemisphere: p = 0.01
Brain - Spinal cord (cervical c-1): p = 0.02
40001_J841Underlying (primary) cause of death: ICD10: J84.1 Other interstitial pulmonary diseases with fibrosisUK Biobank (UKBB)Neale Lab201812089722Uterus: p = 0.00165
Brain - Hypothalamus: p = 0.02
Brain - Hippocampus: p = 0.02
5993ECG, number of stages in a phaseUK Biobank (UKBB)Neale Lab20180539984Uterus: p = 0.00676
Spleen: p = 0.00896
Liver: p = 0.03
6039Duration of fitness testUK Biobank (UKBB)Neale Lab20180539983Spleen: p = 0.00811
Colon - Transverse: p = 0.02
Kidney - Cortex: p = 0.02
20018Prospective memory resultUK Biobank (UKBB)Neale Lab201801197294Pituitary: p = 5.83E-4
Brain - Caudate (basal ganglia): p = 0.00577
Brain - Putamen (basal ganglia): p = 0.00577
20077Number of diet questionnaires completedUK Biobank (UKBB)Neale Lab201801564013Brain - Frontal Cortex (BA9): p = 4.45E-4
Brain - Hypothalamus: p = 6.91E-4
Brain - Cortex: p = 0.0016
20128Number of fluid intelligence questions attempted within time limitUK Biobank (UKBB)Neale Lab201801171315Brain - Putamen (basal ganglia): p = 0.00149
Spleen: p = 0.00149
Prostate: p = 0.00294
20403Amount of alcohol drunk on a typical drinking dayUK Biobank (UKBB)Neale Lab201801082564Brain - Frontal Cortex (BA9): p = 0.00702
Vagina: p = 0.00997
Brain - Cerebellum: p = 0.01
20407Frequency of failure to fulfil normal expectations due to drinking alcohol in last yearUK Biobank (UKBB)Neale Lab20180650543Colon - Transverse: p = 0.00349
Brain - Hypothalamus: p = 0.00725
Esophagus - Gastroesophageal Junction: p = 0.00806
20408Frequency of memory loss due to drinking alcohol in last yearUK Biobank (UKBB)Neale Lab20180650293Skin - Sun Exposed (Lower leg): p = 4.75E-4
Skin - Not Sun Exposed (Suprapubic): p = 0.00294
Esophagus - Mucosa: p = 0.01
20409Frequency of feeling guilt or remorse after drinking alcohol in last yearUK Biobank (UKBB)Neale Lab20180650093Artery - Coronary: p = 0.00454
Brain - Cortex: p = 0.01
Brain - Frontal Cortex (BA9): p = 0.01
20412Frequency of needing morning drink of alcohol after heavy drinking session in last yearUK Biobank (UKBB)Neale Lab20180650993Liver: p = 0.0045
Stomach: p = 0.02
Colon - Transverse: p = 0.05
20413Frequency of inability to cease drinking in last yearUK Biobank (UKBB)Neale Lab20180649733Brain - Cerebellum: p = 0.00208
Brain - Cerebellar Hemisphere: p = 0.00777
Brain - Caudate (basal ganglia): p = 0.01
20414Frequency of drinking alcoholUK Biobank (UKBB)Neale Lab201801179145Liver: p = 8.53E-4
Esophagus - Mucosa: p = 0.00466
Vagina: p = 0.01
20416Frequency of consuming six or more units of alcoholUK Biobank (UKBB)Neale Lab201801084855Brain - Cerebellar Hemisphere: p = 8.18E-6
Brain - Cerebellum: p = 8.18E-6
Brain - Anterior cingulate cortex (BA24): p = 2.37E-5
20418Impact on normal roles during worst period of anxietyUK Biobank (UKBB)Neale Lab20180365053Small Intestine - Terminal Ileum: p = 0.08
Esophagus - Muscularis: p = 0.08
Kidney - Cortex: p = 0.08
20436Fraction of day affected during worst episode of depressionUK Biobank (UKBB)Neale Lab20180624643Colon - Sigmoid: p = 0.00307
Liver: p = 0.00653
Brain - Cerebellum: p = 0.01
20438Duration of worst depressionUK Biobank (UKBB)Neale Lab20180655463Adrenal Gland: p = 0.00993
Brain - Hippocampus: p = 0.02
Pituitary: p = 0.03
20439Frequency of depressed days during worst episode of depressionUK Biobank (UKBB)Neale Lab20180645243Colon - Sigmoid: p = 0.02
Colon - Transverse: p = 0.02
Brain - Amygdala: p = 0.03
20440Impact on normal roles during worst period of depressionUK Biobank (UKBB)Neale Lab20180664293Colon - Transverse: p = 8.98E-5
Kidney - Cortex: p = 0.00117
Colon - Sigmoid: p = 0.00214
20442Lifetime number of depressed periodsUK Biobank (UKBB)Neale Lab20180536913Heart - Atrial Appendage: p = 6.39E-4
Adrenal Gland: p = 0.01
Brain - Cortex: p = 0.02
20453Ever taken cannabisUK Biobank (UKBB)Neale Lab201801179115Spleen: p = 0.00504
Brain - Substantia nigra: p = 0.01
Uterus: p = 0.01
20454Maximum frequency of taking cannabisUK Biobank (UKBB)Neale Lab20180247983Spleen: p = 0.00577
Whole Blood: p = 0.00577
Brain - Spinal cord (cervical c-1): p = 0.02
20458General happinessUK Biobank (UKBB)Neale Lab201801174425Brain - Amygdala: p = 0.00289
Brain - Caudate (basal ganglia): p = 0.00289
Brain - Hypothalamus: p = 0.00289
20459General happiness with own healthUK Biobank (UKBB)Neale Lab201801177535Spleen: p = 5.0E-4
Brain - Cerebellum: p = 0.00169
Pancreas: p = 0.00342
20460Belief that own life is meaningfulUK Biobank (UKBB)Neale Lab201801153524Pituitary: p = 0.00877
Brain - Cortex: p = 0.01
Brain - Frontal Cortex (BA9): p = 0.01
20462Distress caused by unusual or psychotic experiencesUK Biobank (UKBB)Neale Lab2018056633Adipose - Visceral (Omentum): p = 0.02
Breast - Mammary Tissue: p = 0.02
Colon - Sigmoid: p = 0.02
20467Frequency of unusual or psychotic experiences in past yearUK Biobank (UKBB)Neale Lab2018057952Vagina: p = 0.02
Adipose - Subcutaneous: p = 0.03
Breast - Mammary Tissue: p = 0.03
20479Ever thought that life not worth livingUK Biobank (UKBB)Neale Lab201801172914Brain - Cerebellar Hemisphere: p = 0.00169
Brain - Frontal Cortex (BA9): p = 0.00508
Brain - Cerebellum: p = 0.00513
20482Number of times self-harmedUK Biobank (UKBB)Neale Lab2018050083Brain - Cerebellum: p = 0.00564
Brain - Cerebellar Hemisphere: p = 0.00861
Liver: p = 0.02
20485Ever contemplated self-harmUK Biobank (UKBB)Neale Lab201801176103Pancreas: p = 0.01
Spleen: p = 0.01
Artery - Tibial: p = 0.02
20487Felt hated by family member as a childUK Biobank (UKBB)Neale Lab201801177493Brain - Spinal cord (cervical c-1): p = 0.00654
Heart - Left Ventricle: p = 0.00654
Brain - Nucleus accumbens (basal ganglia): p = 0.01
20488Physically abused by family as a childUK Biobank (UKBB)Neale Lab201801178384Adipose - Subcutaneous: p = 0.02
Adipose - Visceral (Omentum): p = 0.02
Esophagus - Gastroesophageal Junction: p = 0.02
20489Felt loved as a childUK Biobank (UKBB)Neale Lab201801176243Brain - Substantia nigra: p = 3.64E-4
Brain - Spinal cord (cervical c-1): p = 0.00125
Brain - Anterior cingulate cortex (BA24): p = 0.00184
20490Sexually molested as a childUK Biobank (UKBB)Neale Lab201801167733Heart - Atrial Appendage: p = 0.01
Colon - Transverse: p = 0.02
Breast - Mammary Tissue: p = 0.02
20491Someone to take to doctor when needed as a childUK Biobank (UKBB)Neale Lab201801173013Esophagus - Mucosa: p = 0.00454
Adipose - Visceral (Omentum): p = 0.02
Colon - Transverse: p = 0.05
20492Longest period of mania or irritabilityUK Biobank (UKBB)Neale Lab20180277223Pituitary: p = 0.00452
Thyroid: p = 0.00532
Esophagus - Muscularis: p = 0.02
20494Felt irritable or had angry outbursts in past monthUK Biobank (UKBB)Neale Lab20180528163Kidney - Cortex: p = 0.04
Heart - Atrial Appendage: p = 0.04
Whole Blood: p = 0.04
20495Avoided activities or situations because of previous stressful experience in past monthUK Biobank (UKBB)Neale Lab201801178683Small Intestine - Terminal Ileum: p = 0.00118
Colon - Transverse: p = 0.01
Brain - Cerebellum: p = 0.03
20496Felt distant from other people in past monthUK Biobank (UKBB)Neale Lab20180528223Uterus: p = 0.00184
Spleen: p = 0.00952
Heart - Atrial Appendage: p = 0.02
20497Repeated disturbing thoughts of stressful experience in past monthUK Biobank (UKBB)Neale Lab201801179003Brain - Spinal cord (cervical c-1): p = 0.00287
Brain - Anterior cingulate cortex (BA24): p = 0.00306
Brain - Frontal Cortex (BA9): p = 0.00306
20498Felt very upset when reminded of stressful experience in past monthUK Biobank (UKBB)Neale Lab201801178934Esophagus - Gastroesophageal Junction: p = 0.0024
Esophagus - Muscularis: p = 0.0024
Nerve - Tibial: p = 0.0042
20505Recent easy annoyance or irritabilityUK Biobank (UKBB)Neale Lab201801174833Adrenal Gland: p = 0.02
Brain - Nucleus accumbens (basal ganglia): p = 0.03
Skin - Not Sun Exposed (Suprapubic): p = 0.03
20506Recent feelings or nervousness or anxietyUK Biobank (UKBB)Neale Lab201801175945Uterus: p = 9.84E-4
Brain - Hypothalamus: p = 0.02
Brain - Putamen (basal ganglia): p = 0.02
20507Recent feelings of inadequacyUK Biobank (UKBB)Neale Lab201801175023Brain - Amygdala: p = 3.99E-4
Brain - Anterior cingulate cortex (BA24): p = 3.99E-4
Brain - Cortex: p = 3.99E-4
20508Recent trouble concentrating on thingsUK Biobank (UKBB)Neale Lab201801178993Heart - Left Ventricle: p = 0.00943
Skin - Not Sun Exposed (Suprapubic): p = 0.00943
Thyroid: p = 0.01
20509Recent inability to stop or control worryingUK Biobank (UKBB)Neale Lab201801175834Artery - Coronary: p = 0.0092
Artery - Tibial: p = 0.02
Liver: p = 0.02
20510Recent feelings of depressionUK Biobank (UKBB)Neale Lab201801176563Vagina: p = 0.01
Adrenal Gland: p = 0.03
Nerve - Tibial: p = 0.03
20511Recent poor appetite or overeatingUK Biobank (UKBB)Neale Lab201801179074Lung: p = 3.41E-4
Artery - Coronary: p = 5.89E-4
Artery - Tibial: p = 0.00186
20512Recent feelings of forebodingUK Biobank (UKBB)Neale Lab201801174744Brain - Cerebellar Hemisphere: p = 0.00794
Brain - Cerebellum: p = 0.00794
Brain - Frontal Cortex (BA9): p = 0.00794
20513Recent thoughts of suicide or self-harmUK Biobank (UKBB)Neale Lab201801171773Heart - Left Ventricle: p = 0.00678
Spleen: p = 0.00743
Heart - Atrial Appendage: p = 0.02
20514Recent lack of interest or pleasure in doing thingsUK Biobank (UKBB)Neale Lab201801177573Heart - Atrial Appendage: p = 0.01
Small Intestine - Terminal Ileum: p = 0.01
Prostate: p = 0.04
20515Recent trouble relaxingUK Biobank (UKBB)Neale Lab201801177063Brain - Anterior cingulate cortex (BA24): p = 0.00207
Brain - Frontal Cortex (BA9): p = 0.00418
Artery - Tibial: p = 0.00466
20516Recent restlessnessUK Biobank (UKBB)Neale Lab201801177863Skin - Sun Exposed (Lower leg): p = 0.00189
Esophagus - Muscularis: p = 0.00443
Skin - Not Sun Exposed (Suprapubic): p = 0.00571
20517Trouble falling or staying asleep, or sleeping too muchUK Biobank (UKBB)Neale Lab201801178223Brain - Amygdala: p = 7.09E-4
Brain - Hypothalamus: p = 0.00109
Brain - Cortex: p = 0.00164
20518Recent changes in speed/amount of moving or speakingUK Biobank (UKBB)Neale Lab201801178683Colon - Transverse: p = 0.01
Liver: p = 0.02
Pituitary: p = 0.02
20519Recent feelings of tiredness or low energyUK Biobank (UKBB)Neale Lab201801178284Nerve - Tibial: p = 0.00395
Brain - Cerebellum: p = 0.00894
Heart - Atrial Appendage: p = 0.00894
20520Recent worrying too much about different thingsUK Biobank (UKBB)Neale Lab201801175673Ovary: p = 0.01
Heart - Atrial Appendage: p = 0.02
Uterus: p = 0.02
20521Belittlement by partner or ex-partner as an adultUK Biobank (UKBB)Neale Lab201801177413Brain - Cerebellar Hemisphere: p = 7.42E-4
Brain - Cerebellum: p = 0.00179
Brain - Frontal Cortex (BA9): p = 0.00179
20522Been in a confiding relationship as an adultUK Biobank (UKBB)Neale Lab201801150993Pituitary: p = 0.05
Brain - Cerebellum: p = 0.08
Esophagus - Gastroesophageal Junction: p = 0.08
20523Physical violence by partner or ex-partner as an adultUK Biobank (UKBB)Neale Lab201801177463Brain - Cerebellum: p = 3.91E-4
Artery - Tibial: p = 9.9E-4
Brain - Caudate (basal ganglia): p = 9.9E-4
20524Sexual interference by partner or ex-partner without consent as an adultUK Biobank (UKBB)Neale Lab201801177273Brain - Cerebellar Hemisphere: p = 0.02
Thyroid: p = 0.02
Brain - Cerebellum: p = 0.03
20525Able to pay rent/mortgage as an adultUK Biobank (UKBB)Neale Lab201801162963Spleen: p = 0.00129
Brain - Spinal cord (cervical c-1): p = 0.00201
Brain - Caudate (basal ganglia): p = 0.00315
20537Frequency of difficulty controlling worry during worst period of anxietyUK Biobank (UKBB)Neale Lab20180361573Brain - Hypothalamus: p = 0.00175
Brain - Anterior cingulate cortex (BA24): p = 0.00952
Brain - Frontal Cortex (BA9): p = 0.02
20539Frequency of inability to stop worrying during worst period of anxietyUK Biobank (UKBB)Neale Lab20180362373Brain - Spinal cord (cervical c-1): p = 0.00619
Pituitary: p = 0.00813
Whole Blood: p = 0.00813
22599Number of jobs heldUK Biobank (UKBB)Neale Lab20180898663Kidney - Cortex: p = 0.01
Brain - Hippocampus: p = 0.02
Muscle - Skeletal: p = 0.02
5992ECG, phase durationUK Biobank (UKBB)Neale Lab201842709112893Skin - Not Sun Exposed (Suprapubic): p = 3.35E-4
Skin - Sun Exposed (Lower leg): p = 0.00588
Kidney - Cortex: p = 0.00962
6015Chest pain felt during physical activityUK Biobank (UKBB)Neale Lab20185206719443Small Intestine - Terminal Ileum: p = 7.29E-4
Adipose - Visceral (Omentum): p = 0.03
Kidney - Cortex: p = 0.03
6016Chest pain felt outside physical activityUK Biobank (UKBB)Neale Lab20185275416623Uterus: p = 0.01
Heart - Left Ventricle: p = 0.01
Nerve - Tibial: p = 0.03
6017Able to walk or cycle unaided for 10 minutesUK Biobank (UKBB)Neale Lab20181911518353Skin - Sun Exposed (Lower leg): p = 0.00298
Skin - Not Sun Exposed (Suprapubic): p = 0.02
Lung: p = 0.08
6020_1Completion status of test: Fully completedUK Biobank (UKBB)Neale Lab20185021537923Pancreas: p = 0.00122
Muscle - Skeletal: p = 0.00165
Adipose - Subcutaneous: p = 0.01
6020_31Completion status of test: Participant wanted to stop earlyUK Biobank (UKBB)Neale Lab2018528534793Spleen: p = 0.00393
Artery - Aorta: p = 0.00993
Artery - Tibial: p = 0.00993
6020_32Completion status of test: Participant reported chest-pain and/or other discomfortUK Biobank (UKBB)Neale Lab2018206538013Spleen: p = 0.00423
Thyroid: p = 0.01
Heart - Atrial Appendage: p = 0.02
6020_33Completion status of test: Heart rate reached safety levelUK Biobank (UKBB)Neale Lab20182923510843Adrenal Gland: p = 0.00921
Nerve - Tibial: p = 0.02
Adipose - Visceral (Omentum): p = 0.03
6020_34Completion status of test: Incomplete - other reasonUK Biobank (UKBB)Neale Lab2018135538723Pancreas: p = 0.01
Esophagus - Muscularis: p = 0.03
Small Intestine - Terminal Ileum: p = 0.05
6034Target heart rate achievedUK Biobank (UKBB)Neale Lab20185554484443Adipose - Visceral (Omentum): p = 0.02
Heart - Left Ventricle: p = 0.03
Adrenal Gland: p = 0.04
6070_1OCT measured (right): MeasurableUK Biobank (UKBB)Neale Lab20184702575833Kidney - Cortex: p = 0.02
Whole Blood: p = 0.05
Artery - Aorta: p = 0.08
6070_6OCT measured (right): Not performed - equipment failureUK Biobank (UKBB)Neale Lab20185376492323Breast - Mammary Tissue: p = 0.04
Pancreas: p = 0.05
Prostate: p = 0.05
6070_7OCT measured (right): Not performed - other reasonUK Biobank (UKBB)Neale Lab20182207524013Small Intestine - Terminal Ileum: p = 0.00623
Esophagus - Gastroesophageal Junction: p = 0.03
Esophagus - Muscularis: p = 0.03
6072_1OCT measured (left): MeasurableUK Biobank (UKBB)Neale Lab20184672978723Kidney - Cortex: p = 2.0E-5
Liver: p = 0.02
Brain - Cerebellum: p = 0.02
6072_6OCT measured (left): Not performed - equipment failureUK Biobank (UKBB)Neale Lab20185540490613Pancreas: p = 0.05
Pituitary: p = 0.05
Vagina: p = 0.09
6072_7OCT measured (left): Not performed - other reasonUK Biobank (UKBB)Neale Lab20182332522693Liver: p = 8.94E-4
Brain - Cerebellum: p = 0.01
Esophagus - Mucosa: p = 0.03
6138_3Qualifications: O levels/GCSEs or equivalentUK Biobank (UKBB)Neale Lab20181686721888774Brain - Caudate (basal ganglia): p = 8.58E-7
Brain - Putamen (basal ganglia): p = 1.68E-6
Brain - Nucleus accumbens (basal ganglia): p = 3.24E-6
6138_100Qualifications: None of the aboveUK Biobank (UKBB)Neale Lab2018610932964563Brain - Putamen (basal ganglia): p = 4.18E-10
Brain - Hippocampus: p = 9.59E-10
Brain - Frontal Cortex (BA9): p = 2.17E-9
6138_2Qualifications: A levels/AS levels or equivalentUK Biobank (UKBB)Neale Lab2018983042592454Brain - Putamen (basal ganglia): p = 2.48E-11
Brain - Frontal Cortex (BA9): p = 4.87E-11
Brain - Anterior cingulate cortex (BA24): p = 9.48E-11
6138_6Qualifications: Other professional qualifications eg: nursing, teachingUK Biobank (UKBB)Neale Lab20181042412533084Brain - Cortex: p = 3.93E-5
Brain - Amygdala: p = 2.24E-4
Brain - Cerebellar Hemisphere: p = 2.24E-4
6138_5Qualifications: NVQ or HND or HNC or equivalentUK Biobank (UKBB)Neale Lab2018665442910054Brain - Caudate (basal ganglia): p = 0.00196
Brain - Putamen (basal ganglia): p = 0.00844
Brain - Nucleus accumbens (basal ganglia): p = 0.01
6138_4Qualifications: CSEs or equivalentUK Biobank (UKBB)Neale Lab2018466723108774Brain - Amygdala: p = 0.00485
Brain - Anterior cingulate cortex (BA24): p = 0.00485
Brain - Frontal Cortex (BA9): p = 0.00485
6139_100Gas or solid-fuel cooking/heating: None of the aboveUK Biobank (UKBB)Neale Lab2018636532964133Lung: p = 0.00843
Artery - Tibial: p = 0.01
Kidney - Cortex: p = 0.01
6139_1Gas or solid-fuel cooking/heating: A gas hob or gas cookerUK Biobank (UKBB)Neale Lab20182516801083863Brain - Hippocampus: p = 0.00142
Brain - Nucleus accumbens (basal ganglia): p = 0.00276
Colon - Transverse: p = 0.00276
6139_3Gas or solid-fuel cooking/heating: An open solid fuel fire that you use regularly in winter timeUK Biobank (UKBB)Neale Lab2018326623274044Adipose - Subcutaneous: p = 0.00899
Artery - Tibial: p = 0.02
Adipose - Visceral (Omentum): p = 0.03
6139_2Gas or solid-fuel cooking/heating: A gas fire that you use regularly in winter timeUK Biobank (UKBB)Neale Lab20181453152147513Brain - Anterior cingulate cortex (BA24): p = 3.57E-4
Brain - Cortex: p = 0.00224
Brain - Frontal Cortex (BA9): p = 0.00224
6140_1Heating type(s) in home: Gas central heatingUK Biobank (UKBB)Neale Lab201811028396252Small Intestine - Terminal Ileum: p = 0.00527
Lung: p = 0.01
Breast - Mammary Tissue: p = 0.03
6140_100Heating type(s) in home: None of the aboveUK Biobank (UKBB)Neale Lab201822891176193Muscle - Skeletal: p = 0.00933
Testis: p = 0.01
Kidney - Cortex: p = 0.02
6140_3Heating type(s) in home: Oil (kerosene) central heatingUK Biobank (UKBB)Neale Lab201831181167902Brain - Cerebellum: p = 0.01
Brain - Cerebellar Hemisphere: p = 0.02
Brain - Hippocampus: p = 0.02
6140_6Heating type(s) in home: Open fire without central heatingUK Biobank (UKBB)Neale Lab20184591194493Colon - Sigmoid: p = 0.00108
Lung: p = 0.00414
Brain - Nucleus accumbens (basal ganglia): p = 0.01
6140_2Heating type(s) in home: Electric storage heatersUK Biobank (UKBB)Neale Lab201835461163623Whole Blood: p = 0.00488
Thyroid: p = 0.01
Brain - Nucleus accumbens (basal ganglia): p = 0.02
6140_5Heating type(s) in home: Solid fuel central heatingUK Biobank (UKBB)Neale Lab20187461191623Brain - Caudate (basal ganglia): p = 3.39E-4
Brain - Putamen (basal ganglia): p = 9.83E-4
Brain - Hypothalamus: p = 0.00119
6140_4Heating type(s) in home: Portable gas or paraffin heatersUK Biobank (UKBB)Neale Lab20183241195843Artery - Aorta: p = 2.56E-4
Artery - Coronary: p = 0.0031
Artery - Tibial: p = 0.01
6141_1How are people in household related to participant: Husband, wife or partnerUK Biobank (UKBB)Neale Lab2018265738932254Brain - Frontal Cortex (BA9): p = 0.00133
Brain - Caudate (basal ganglia): p = 0.00286
Brain - Cortex: p = 0.00286
6141_8How are people in household related to participant: Other unrelatedUK Biobank (UKBB)Neale Lab201861543528093Colon - Transverse: p = 0.00638
Esophagus - Gastroesophageal Junction: p = 0.04
Pancreas: p = 0.06
6141_2How are people in household related to participant: Son and/or daughter (include step-children)UK Biobank (UKBB)Neale Lab20181210712378923Esophagus - Gastroesophageal Junction: p = 0.01
Brain - Hypothalamus: p = 0.01
Brain - Cortex: p = 0.02
6141_7How are people in household related to participant: Other relatedUK Biobank (UKBB)Neale Lab201819873569763Adrenal Gland: p = 5.72E-4
Artery - Tibial: p = 0.07
Colon - Sigmoid: p = 0.07
6141_4How are people in household related to participant: Mother and/or fatherUK Biobank (UKBB)Neale Lab201863023526613Esophagus - Gastroesophageal Junction: p = 0.02
Kidney - Cortex: p = 0.03
Skin - Not Sun Exposed (Suprapubic): p = 0.04
6141_3How are people in household related to participant: Brother and/or sisterUK Biobank (UKBB)Neale Lab201816513573123Adrenal Gland: p = 0.04
Liver: p = 0.08
Minor Salivary Gland: p = 0.09
6141_6How are people in household related to participant: GrandchildUK Biobank (UKBB)Neale Lab201829073560562Liver: p = 0.00566
Esophagus - Mucosa: p = 0.03
Brain - Spinal cord (cervical c-1): p = 0.05
6141_5How are people in household related to participant: GrandparentUK Biobank (UKBB)Neale Lab20181023588613Skin - Sun Exposed (Lower leg): p = 0.00321
Skin - Not Sun Exposed (Suprapubic): p = 0.01
Colon - Transverse: p = 0.02
6142_2Current employment status: RetiredUK Biobank (UKBB)Neale Lab20181329312270003Muscle - Skeletal: p = 0.00415
Colon - Sigmoid: p = 0.02
Uterus: p = 0.02
6142_1Current employment status: In paid employment or self-employedUK Biobank (UKBB)Neale Lab20182051491547824Brain - Putamen (basal ganglia): p = 0.01
Brain - Caudate (basal ganglia): p = 0.02
Brain - Frontal Cortex (BA9): p = 0.02
6142_5Current employment status: UnemployedUK Biobank (UKBB)Neale Lab201856943542373Adipose - Subcutaneous: p = 0.01
Pituitary: p = 0.02
Adipose - Visceral (Omentum): p = 0.04
6142_4Current employment status: Unable to work because of sickness or disabilityUK Biobank (UKBB)Neale Lab2018137563461754Artery - Aorta: p = 7.18E-7
Artery - Coronary: p = 4.41E-5
Uterus: p = 5.69E-5
6142_3Current employment status: Looking after home and/or familyUK Biobank (UKBB)Neale Lab2018180143419173Brain - Anterior cingulate cortex (BA24): p = 0.00806
Brain - Frontal Cortex (BA9): p = 0.00806
Brain - Spinal cord (cervical c-1): p = 0.00806
6142_6Current employment status: Doing unpaid or voluntary workUK Biobank (UKBB)Neale Lab2018133083466233Brain - Nucleus accumbens (basal ganglia): p = 0.01
Testis: p = 0.01
Brain - Caudate (basal ganglia): p = 0.01
6142_7Current employment status: Full or part-time studentUK Biobank (UKBB)Neale Lab201828183571133Kidney - Cortex: p = 1.67E-4
Brain - Cortex: p = 0.00199
Brain - Cerebellar Hemisphere: p = 0.01
6142_100Current employment status: None of the aboveUK Biobank (UKBB)Neale Lab201817303582013Artery - Aorta: p = 3.25E-5
Artery - Coronary: p = 0.00264
Uterus: p = 0.00421
6143_1Transport type for commuting to job workplace: Car/motor vehicleUK Biobank (UKBB)Neale Lab2018152481383513Brain - Nucleus accumbens (basal ganglia): p = 0.00244
Brain - Cortex: p = 0.0037
Brain - Anterior cingulate cortex (BA24): p = 0.00812
6143_3Transport type for commuting to job workplace: Public transportUK Biobank (UKBB)Neale Lab2018396551511773Brain - Cerebellum: p = 0.00134
Brain - Caudate (basal ganglia): p = 0.00257
Brain - Cerebellar Hemisphere: p = 0.00262
6143_2Transport type for commuting to job workplace: WalkUK Biobank (UKBB)Neale Lab2018302871605453Brain - Cerebellar Hemisphere: p = 7.35E-4
Brain - Cerebellum: p = 0.00116
Brain - Substantia nigra: p = 0.00255
6143_4Transport type for commuting to job workplace: CycleUK Biobank (UKBB)Neale Lab2018148851759474Brain - Hippocampus: p = 8.22E-4
Brain - Amygdala: p = 0.00273
Brain - Caudate (basal ganglia): p = 0.00273
6143_100Transport type for commuting to job workplace: None of the aboveUK Biobank (UKBB)Neale Lab20187891900432Esophagus - Muscularis: p = 0.00603
Skin - Not Sun Exposed (Suprapubic): p = 0.01
Esophagus - Gastroesophageal Junction: p = 0.01
6144_5Never eat eggs, dairy, wheat, sugar: I eat all of the aboveUK Biobank (UKBB)Neale Lab2018278162816154Spleen: p = 4.73E-6
Lung: p = 1.89E-5
Brain - Cerebellum: p = 1.26E-4
6144_3Never eat eggs, dairy, wheat, sugar: Wheat productsUK Biobank (UKBB)Neale Lab201895733502045Spleen: p = 1.61E-8
Lung: p = 1.31E-5
Whole Blood: p = 0.00108
6144_4Never eat eggs, dairy, wheat, sugar: Sugar or foods/drinks containing sugarUK Biobank (UKBB)Neale Lab2018672922924854Brain - Cortex: p = 3.47E-5
Brain - Frontal Cortex (BA9): p = 0.00129
Brain - Anterior cingulate cortex (BA24): p = 0.00315
6144_1Never eat eggs, dairy, wheat, sugar: Eggs or foods containing eggsUK Biobank (UKBB)Neale Lab201893153504623Ovary: p = 0.01
Nerve - Tibial: p = 0.01
Breast - Mammary Tissue: p = 0.03
6144_2Never eat eggs, dairy, wheat, sugar: Dairy productsUK Biobank (UKBB)Neale Lab201879233518543Ovary: p = 0.04
Testis: p = 0.04
Brain - Frontal Cortex (BA9): p = 0.07
6145_1Illness, injury, bereavement, stress in last 2 years: Serious illness, injury or assault to yourselfUK Biobank (UKBB)Neale Lab2018332413255953Minor Salivary Gland: p = 0.00379
Esophagus - Muscularis: p = 0.01
Heart - Atrial Appendage: p = 0.03
6145_100Illness, injury, bereavement, stress in last 2 years: None of the aboveUK Biobank (UKBB)Neale Lab20182018511569853Brain - Substantia nigra: p = 0.00192
Brain - Caudate (basal ganglia): p = 0.00404
Brain - Nucleus accumbens (basal ganglia): p = 0.00404
6145_2Illness, injury, bereavement, stress in last 2 years: Serious illness, injury or assault of a close relativeUK Biobank (UKBB)Neale Lab2018414593173773Colon - Sigmoid: p = 2.52E-4
Uterus: p = 4.29E-4
Artery - Aorta: p = 0.00381
6145_3Illness, injury, bereavement, stress in last 2 years: Death of a close relativeUK Biobank (UKBB)Neale Lab2018753052835313Testis: p = 0.00161
Ovary: p = 0.01
Skin - Sun Exposed (Lower leg): p = 0.02
6145_6Illness, injury, bereavement, stress in last 2 years: Financial difficultiesUK Biobank (UKBB)Neale Lab2018406703181664Brain - Nucleus accumbens (basal ganglia): p = 1.53E-6
Brain - Caudate (basal ganglia): p = 7.03E-6
Brain - Putamen (basal ganglia): p = 1.15E-5
6145_5Illness, injury, bereavement, stress in last 2 years: Marital separation/divorceUK Biobank (UKBB)Neale Lab2018108163480203Colon - Sigmoid: p = 0.00332
Kidney - Cortex: p = 0.03
Muscle - Skeletal: p = 0.03
6145_4Illness, injury, bereavement, stress in last 2 years: Death of a spouse or partnerUK Biobank (UKBB)Neale Lab201855883532483Kidney - Cortex: p = 0.01
Artery - Aorta: p = 0.02
Uterus: p = 0.02
6146_100Attendance/disability/mobility allowance: None of the aboveUK Biobank (UKBB)Neale Lab2018337879207184Lung: p = 0.00286
Brain - Caudate (basal ganglia): p = 0.0029
Artery - Aorta: p = 0.00785
6146_2Attendance/disability/mobility allowance: Disability living allowanceUK Biobank (UKBB)Neale Lab2018156973429004Skin - Not Sun Exposed (Suprapubic): p = 0.00152
Skin - Sun Exposed (Lower leg): p = 0.00152
Colon - Sigmoid: p = 0.00263
6146_1Attendance/disability/mobility allowance: Attendance allowanceUK Biobank (UKBB)Neale Lab201825243560733Brain - Caudate (basal ganglia): p = 0.02
Brain - Putamen (basal ganglia): p = 0.02
Pituitary: p = 0.02
6146_3Attendance/disability/mobility allowance: Blue badgeUK Biobank (UKBB)Neale Lab2018127333458644Brain - Frontal Cortex (BA9): p = 5.56E-4
Heart - Atrial Appendage: p = 0.00398
Brain - Caudate (basal ganglia): p = 0.00547
6147_6Reason for glasses/contact lenses: For a 'lazy' eye or an eye with poor vision since childhood (called 'amblyopia')UK Biobank (UKBB)Neale Lab201829643577133Whole Blood: p = 0.00548
Pancreas: p = 0.0071
Artery - Tibial: p = 0.00761
6147_3Reason for glasses/contact lenses: For just reading/near work as you are getting older (called 'presbyopia')UK Biobank (UKBB)Neale Lab2018314963291813Kidney - Cortex: p = 0.00179
Brain - Caudate (basal ganglia): p = 0.00716
Brain - Putamen (basal ganglia): p = 0.03
6147_2Reason for glasses/contact lenses: For long-sightedness, i.e. for distance and near, but particularly for near tasks like reading (called 'hypermetropia')UK Biobank (UKBB)Neale Lab2018150913455864Uterus: p = 4.69E-4
Artery - Aorta: p = 0.00106
Artery - Coronary: p = 0.00363
6147_1Reason for glasses/contact lenses: For short-sightedness, i.e. only or mainly for distance viewing such as driving, cinema etc (called 'myopia')UK Biobank (UKBB)Neale Lab2018293183313595Brain - Cerebellum: p = 2.44E-4
Brain - Cerebellar Hemisphere: p = 6.24E-4
Brain - Amygdala: p = 0.00208
6147_4Reason for glasses/contact lenses: For 'astigmatism'UK Biobank (UKBB)Neale Lab201897523509253Minor Salivary Gland: p = 0.00943
Prostate: p = 0.02
Brain - Cerebellum: p = 0.03
6147_7Reason for glasses/contact lenses: Other eye conditionUK Biobank (UKBB)Neale Lab201812713594063Muscle - Skeletal: p = 1.46E-4
Artery - Tibial: p = 0.00804
Pancreas: p = 0.02
6147_5Reason for glasses/contact lenses: For a 'squint' or 'turn' in an eye since childhood (called 'strabismus')UK Biobank (UKBB)Neale Lab201815663591113Thyroid: p = 0.00843
Breast - Mammary Tissue: p = 0.00975
Minor Salivary Gland: p = 0.01
6148_100Eye problems/disorders: None of the aboveUK Biobank (UKBB)Neale Lab201891941259494Spleen: p = 1.83E-4
Whole Blood: p = 9.48E-4
Small Intestine - Terminal Ileum: p = 0.00886
6148_6Eye problems/disorders: Other serious eye conditionUK Biobank (UKBB)Neale Lab201865871113033Brain - Cerebellar Hemisphere: p = 0.02
Brain - Cerebellum: p = 0.02
Brain - Spinal cord (cervical c-1): p = 0.02
6148_4Eye problems/disorders: CataractUK Biobank (UKBB)Neale Lab2018111941066963Heart - Atrial Appendage: p = 0.01
Small Intestine - Terminal Ileum: p = 0.02
Colon - Transverse: p = 0.04
6148_1Eye problems/disorders: Diabetes related eye diseaseUK Biobank (UKBB)Neale Lab201822491156415Lung: p = 5.4E-7
Spleen: p = 2.3E-5
Small Intestine - Terminal Ileum: p = 0.00123
6148_5Eye problems/disorders: Macular degenerationUK Biobank (UKBB)Neale Lab201827261151643Liver: p = 1.35E-4
Spleen: p = 7.93E-4
Whole Blood: p = 0.05
6148_2Eye problems/disorders: GlaucomaUK Biobank (UKBB)Neale Lab201850921127985Adipose - Subcutaneous: p = 2.63E-6
Breast - Mammary Tissue: p = 6.33E-5
Artery - Coronary: p = 1.03E-4
6148_3Eye problems/disorders: Injury or trauma resulting in loss of visionUK Biobank (UKBB)Neale Lab201821511157393Brain - Cerebellum: p = 5.17E-4
Brain - Cerebellar Hemisphere: p = 0.00229
Thyroid: p = 0.00993
6149_100Mouth/teeth dental problems: None of the aboveUK Biobank (UKBB)Neale Lab20182183461414954Spleen: p = 1.21E-6
Whole Blood: p = 1.64E-6
Lung: p = 2.34E-4
6149_6Mouth/teeth dental problems: DenturesUK Biobank (UKBB)Neale Lab2018609772988644Spleen: p = 5.23E-5
Lung: p = 5.98E-4
Colon - Transverse: p = 0.0022
6149_4Mouth/teeth dental problems: Loose teethUK Biobank (UKBB)Neale Lab2018143643454773Brain - Caudate (basal ganglia): p = 0.01
Whole Blood: p = 0.02
Brain - Putamen (basal ganglia): p = 0.03
6149_3Mouth/teeth dental problems: Bleeding gumsUK Biobank (UKBB)Neale Lab2018466943131475Minor Salivary Gland: p = 0.00385
Esophagus - Muscularis: p = 0.00671
Small Intestine - Terminal Ileum: p = 0.00957
6149_1Mouth/teeth dental problems: Mouth ulcersUK Biobank (UKBB)Neale Lab2018368313230104Spleen: p = 1.74E-12
Whole Blood: p = 2.64E-8
Lung: p = 1.39E-6
6149_2Mouth/teeth dental problems: Painful gumsUK Biobank (UKBB)Neale Lab2018101153497263Colon - Sigmoid: p = 0.00268
Uterus: p = 0.00404
Spleen: p = 0.02
6149_5Mouth/teeth dental problems: ToothacheUK Biobank (UKBB)Neale Lab2018144773453643Esophagus - Muscularis: p = 0.00184
Nerve - Tibial: p = 0.00184
Brain - Frontal Cortex (BA9): p = 0.00749
6150_100Vascular/heart problems diagnosed by doctor: None of the aboveUK Biobank (UKBB)Neale Lab20182535651068553Uterus: p = 4.64E-4
Prostate: p = 4.78E-4
Artery - Tibial: p = 0.0029
6150_4Vascular/heart problems diagnosed by doctor: High blood pressureUK Biobank (UKBB)Neale Lab2018971392632813Uterus: p = 1.52E-4
Artery - Tibial: p = 9.21E-4
Heart - Atrial Appendage: p = 0.00561
6150_1Vascular/heart problems diagnosed by doctor: Heart attackUK Biobank (UKBB)Neale Lab201882883521325Artery - Coronary: p = 4.35E-5
Artery - Tibial: p = 1.07E-4
Esophagus - Gastroesophageal Junction: p = 2.54E-4
6150_2Vascular/heart problems diagnosed by doctor: AnginaUK Biobank (UKBB)Neale Lab2018113723490485Lung: p = 1.67E-4
Uterus: p = 3.84E-4
Artery - Coronary: p = 0.002
6150_3Vascular/heart problems diagnosed by doctor: StrokeUK Biobank (UKBB)Neale Lab201855873548333Heart - Atrial Appendage: p = 0.03
Adipose - Subcutaneous: p = 0.04
Liver: p = 0.04
6151_1Fractured bone site(s): AnkleUK Biobank (UKBB)Neale Lab201850683541733Colon - Transverse: p = 4.96E-4
Small Intestine - Terminal Ileum: p = 0.006
Kidney - Cortex: p = 0.01
6151_7Fractured bone site(s): Other bonesUK Biobank (UKBB)Neale Lab2018187873404544Skin - Sun Exposed (Lower leg): p = 0.00649
Stomach: p = 0.02
Skin - Not Sun Exposed (Suprapubic): p = 0.02
6151_2Fractured bone site(s): LegUK Biobank (UKBB)Neale Lab201823113569303Vagina: p = 0.03
Pancreas: p = 0.03
Esophagus - Muscularis: p = 0.05
6151_5Fractured bone site(s): WristUK Biobank (UKBB)Neale Lab201872003520413Artery - Coronary: p = 0.00274
Skin - Not Sun Exposed (Suprapubic): p = 0.00389
Adipose - Subcutaneous: p = 0.00517
6151_6Fractured bone site(s): ArmUK Biobank (UKBB)Neale Lab201836763555653Vagina: p = 0.00329
Minor Salivary Gland: p = 0.0051
Artery - Tibial: p = 0.00777
6151_3Fractured bone site(s): HipUK Biobank (UKBB)Neale Lab20186673585743Nerve - Tibial: p = 0.00745
Spleen: p = 0.02
Artery - Aorta: p = 0.02
6151_4Fractured bone site(s): SpineUK Biobank (UKBB)Neale Lab20188123584293Pancreas: p = 6.8E-4
Whole Blood: p = 0.02
Artery - Aorta: p = 0.06
6152_100Blood clot, DVT, bronchitis, emphysema, asthma, rhinitis, eczema, allergy diagnosed by doctor: None of the aboveUK Biobank (UKBB)Neale Lab20182445221160054Whole Blood: p = 1.47E-9
Spleen: p = 1.08E-7
Lung: p = 1.9E-4
6152_8Blood clot, DVT, bronchitis, emphysema, asthma, rhinitis, eczema, allergy diagnosed by doctor: AsthmaUK Biobank (UKBB)Neale Lab2018416333188944Whole Blood: p = 2.01E-8
Spleen: p = 1.55E-6
Lung: p = 3.17E-4
6152_9Blood clot, DVT, bronchitis, emphysema, asthma, rhinitis, eczema, allergy diagnosed by doctor: Hayfever, allergic rhinitis or eczemaUK Biobank (UKBB)Neale Lab2018834072771204Whole Blood: p = 5.15E-10
Spleen: p = 4.6E-9
Lung: p = 8.46E-5
6152_6Blood clot, DVT, bronchitis, emphysema, asthma, rhinitis, eczema, allergy diagnosed by doctor: Emphysema/chronic bronchitisUK Biobank (UKBB)Neale Lab201861383543893Muscle - Skeletal: p = 0.00438
Whole Blood: p = 0.00813
Spleen: p = 0.00846
6152_7Blood clot, DVT, bronchitis, emphysema, asthma, rhinitis, eczema, allergy diagnosed by doctor: Blood clot in the lungUK Biobank (UKBB)Neale Lab201829843575434Liver: p = 1.73E-6
Stomach: p = 3.56E-5
Uterus: p = 0.00798
6152_5Blood clot, DVT, bronchitis, emphysema, asthma, rhinitis, eczema, allergy diagnosed by doctor: Blood clot in the leg (DVT)UK Biobank (UKBB)Neale Lab201873863531415Stomach: p = 3.85E-5
Liver: p = 4.05E-5
Adipose - Visceral (Omentum): p = 0.00447
6153_1Medication for cholesterol, blood pressure, diabetes, or take exogenous hormones: Cholesterol lowering medicationUK Biobank (UKBB)Neale Lab2018242471689014Liver: p = 6.52E-9
Spleen: p = 0.00297
Lung: p = 0.00534
6153_100Medication for cholesterol, blood pressure, diabetes, or take exogenous hormones: None of the aboveUK Biobank (UKBB)Neale Lab2018133338598104Liver: p = 1.04E-4
Prostate: p = 0.00199
Kidney - Cortex: p = 0.00674
6153_2Medication for cholesterol, blood pressure, diabetes, or take exogenous hormones: Blood pressure medicationUK Biobank (UKBB)Neale Lab2018335191596294Colon - Sigmoid: p = 0.00134
Prostate: p = 0.00141
Kidney - Cortex: p = 0.00341
6153_5Medication for cholesterol, blood pressure, diabetes, or take exogenous hormones: Oral contraceptive pill or minipillUK Biobank (UKBB)Neale Lab201850421881063Whole Blood: p = 0.00107
Spleen: p = 0.00639
Pancreas: p = 0.02
6153_4Medication for cholesterol, blood pressure, diabetes, or take exogenous hormones: Hormone replacement therapyUK Biobank (UKBB)Neale Lab2018143851787633Adrenal Gland: p = 0.00365
Brain - Hippocampus: p = 0.00794
Brain - Cortex: p = 0.02
6153_3Medication for cholesterol, blood pressure, diabetes, or take exogenous hormones: InsulinUK Biobank (UKBB)Neale Lab201814761916725Spleen: p = 2.91E-6
Lung: p = 2.55E-4
Whole Blood: p = 7.86E-4
6154_1Medication for pain relief, constipation, heartburn: AspirinUK Biobank (UKBB)Neale Lab2018502043068805Artery - Tibial: p = 9.97E-4
Uterus: p = 0.00513
Artery - Coronary: p = 0.00637
6154_100Medication for pain relief, constipation, heartburn: None of the aboveUK Biobank (UKBB)Neale Lab20181980431590414Lung: p = 7.0E-4
Brain - Caudate (basal ganglia): p = 0.00629
Spleen: p = 0.00726
6154_3Medication for pain relief, constipation, heartburn: ParacetamolUK Biobank (UKBB)Neale Lab2018779362791484Lung: p = 6.39E-4
Spleen: p = 9.32E-4
Whole Blood: p = 0.00805
6154_2Medication for pain relief, constipation, heartburn: Ibuprofen (e.g. Nurofen)UK Biobank (UKBB)Neale Lab2018530493040354Artery - Aorta: p = 0.04
Artery - Tibial: p = 0.04
Vagina: p = 0.04
6154_4Medication for pain relief, constipation, heartburn: Ranitidine (e.g. Zantac)UK Biobank (UKBB)Neale Lab201868263502583Stomach: p = 0.03
Brain - Spinal cord (cervical c-1): p = 0.09
Minor Salivary Gland: p = 0.09
6154_5Medication for pain relief, constipation, heartburn: Omeprazole (e.g. Zanprol)UK Biobank (UKBB)Neale Lab2018214643356204Kidney - Cortex: p = 0.00101
Pancreas: p = 0.01
Prostate: p = 0.04
6154_6Medication for pain relief, constipation, heartburn: Laxatives (e.g. Dulcolax, Senokot)UK Biobank (UKBB)Neale Lab2018103073467773Colon - Sigmoid: p = 5.17E-4
Lung: p = 0.0073
Pancreas: p = 0.02
6155_2Vitamin and mineral supplements: Vitamin BUK Biobank (UKBB)Neale Lab2018147923444533Muscle - Skeletal: p = 0.04
Breast - Mammary Tissue: p = 0.05
Nerve - Tibial: p = 0.05
6155_100Vitamin and mineral supplements: None of the aboveUK Biobank (UKBB)Neale Lab20182467811124645Brain - Caudate (basal ganglia): p = 1.28E-6
Brain - Anterior cingulate cortex (BA24): p = 3.55E-6
Brain - Frontal Cortex (BA9): p = 5.83E-6
6155_4Vitamin and mineral supplements: Vitamin DUK Biobank (UKBB)Neale Lab2018136873455583Brain - Amygdala: p = 9.95E-4
Brain - Caudate (basal ganglia): p = 0.00519
Brain - Cerebellum: p = 0.01
6155_3Vitamin and mineral supplements: Vitamin CUK Biobank (UKBB)Neale Lab2018309503282954Brain - Cerebellum: p = 0.00306
Spleen: p = 0.00913
Whole Blood: p = 0.01
6155_7Vitamin and mineral supplements: Multivitamins +/- mineralsUK Biobank (UKBB)Neale Lab2018774722817734Brain - Caudate (basal ganglia): p = 1.09E-4
Brain - Cerebellum: p = 1.69E-4
Brain - Anterior cingulate cortex (BA24): p = 2.61E-4
6155_1Vitamin and mineral supplements: Vitamin AUK Biobank (UKBB)Neale Lab201867353525103Colon - Sigmoid: p = 0.03
Adipose - Subcutaneous: p = 0.09
Thyroid: p = 0.09
6155_6Vitamin and mineral supplements: Folic acid or Folate (Vit B9)UK Biobank (UKBB)Neale Lab201876033516423Spleen: p = 8.21E-6
Esophagus - Mucosa: p = 8.17E-5
Adrenal Gland: p = 0.00578
6155_5Vitamin and mineral supplements: Vitamin EUK Biobank (UKBB)Neale Lab2018103563488893Heart - Left Ventricle: p = 0.01
Adipose - Subcutaneous: p = 0.06
Lung: p = 0.06
6156_100Manic/hyper symptoms: None of the aboveUK Biobank (UKBB)Neale Lab20188672153773Kidney - Cortex: p = 0.04
Stomach: p = 0.06
Adipose - Visceral (Omentum): p = 0.08
6156_14Manic/hyper symptoms: I was more creative or had more ideas than usualUK Biobank (UKBB)Neale Lab20182850211993Skin - Sun Exposed (Lower leg): p = 0.00825
Skin - Not Sun Exposed (Suprapubic): p = 0.01
Esophagus - Mucosa: p = 0.02
6156_11Manic/hyper symptoms: I was more active than usualUK Biobank (UKBB)Neale Lab20186030180193Brain - Cerebellum: p = 0.01
Esophagus - Mucosa: p = 0.02
Brain - Anterior cingulate cortex (BA24): p = 0.03
6156_12Manic/hyper symptoms: I was more talkative than usualUK Biobank (UKBB)Neale Lab20185027190223Minor Salivary Gland: p = 0.03
Artery - Coronary: p = 0.05
Esophagus - Mucosa: p = 0.05
6156_15Manic/hyper symptoms: All of the aboveUK Biobank (UKBB)Neale Lab20182431216183Colon - Sigmoid: p = 5.58E-5
Esophagus - Gastroesophageal Junction: p = 5.72E-4
Esophagus - Muscularis: p = 5.72E-4
6156_13Manic/hyper symptoms: I needed less sleep than usualUK Biobank (UKBB)Neale Lab20183259207903Prostate: p = 0.04
Thyroid: p = 0.04
Stomach: p = 0.05
6157_1Why stopped smoking: Illness or ill healthUK Biobank (UKBB)Neale Lab201810637778793Vagina: p = 0.00126
Colon - Transverse: p = 0.00324
Adrenal Gland: p = 0.00578
6157_100Why stopped smoking: None of the aboveUK Biobank (UKBB)Neale Lab201817748707684Ovary: p = 0.01
Artery - Coronary: p = 0.02
Artery - Tibial: p = 0.03
6157_3Why stopped smoking: Health precautionUK Biobank (UKBB)Neale Lab201855663328535Small Intestine - Terminal Ileum: p = 0.00135
Spleen: p = 0.00137
Esophagus - Gastroesophageal Junction: p = 0.004
6157_4Why stopped smoking: Financial reasonsUK Biobank (UKBB)Neale Lab201821653668633Lung: p = 0.00993
Esophagus - Gastroesophageal Junction: p = 0.04
Thyroid: p = 0.17
6157_2Why stopped smoking: Doctor's adviceUK Biobank (UKBB)Neale Lab20186356821603Lung: p = 2.18E-4
Vagina: p = 0.02
Brain - Cortex: p = 0.03
6158_100Why reduced smoking: None of the aboveUK Biobank (UKBB)Neale Lab2018327781663Esophagus - Gastroesophageal Junction: p = 0.04
Esophagus - Muscularis: p = 0.04
Lung: p = 0.04
6158_2Why reduced smoking: Doctor's adviceUK Biobank (UKBB)Neale Lab2018163998042Pancreas: p = 0.00862
Adipose - Subcutaneous: p = 0.03
Muscle - Skeletal: p = 0.04
6158_3Why reduced smoking: Health precautionUK Biobank (UKBB)Neale Lab2018544360003Brain - Hypothalamus: p = 0.02
Brain - Substantia nigra: p = 0.02
Uterus: p = 0.02
6158_1Why reduced smoking: Illness or ill healthUK Biobank (UKBB)Neale Lab2018160498393Colon - Transverse: p = 0.00845
Kidney - Cortex: p = 0.02
Colon - Sigmoid: p = 0.08
6158_4Why reduced smoking: Financial reasonsUK Biobank (UKBB)Neale Lab2018308783563Adrenal Gland: p = 0.00206
Pituitary: p = 0.02
Heart - Left Ventricle: p = 0.02
6159_4Pain type(s) experienced in last month: Back painUK Biobank (UKBB)Neale Lab2018913492690424Brain - Hippocampus: p = 5.36E-6
Brain - Cortex: p = 2.02E-5
Brain - Amygdala: p = 3.82E-5
6159_100Pain type(s) experienced in last month: None of the aboveUK Biobank (UKBB)Neale Lab20181455142148774Brain - Amygdala: p = 3.5E-4
Brain - Cortex: p = 8.74E-4
Brain - Cerebellar Hemisphere: p = 0.00206
6159_3Pain type(s) experienced in last month: Neck or shoulder painUK Biobank (UKBB)Neale Lab2018821202782714Brain - Hippocampus: p = 3.99E-6
Brain - Cortex: p = 8.14E-6
Brain - Amygdala: p = 1.62E-5
6159_5Pain type(s) experienced in last month: Stomach or abdominal painUK Biobank (UKBB)Neale Lab2018303063300854Uterus: p = 3.09E-5
Esophagus - Gastroesophageal Junction: p = 0.00395
Lung: p = 0.00681
6159_7Pain type(s) experienced in last month: Knee painUK Biobank (UKBB)Neale Lab2018766282837634Pancreas: p = 7.13E-4
Artery - Aorta: p = 0.01
Brain - Amygdala: p = 0.02
6159_1Pain type(s) experienced in last month: HeadacheUK Biobank (UKBB)Neale Lab2018716722887194Esophagus - Gastroesophageal Junction: p = 3.1E-4
Artery - Aorta: p = 0.00623
Colon - Sigmoid: p = 0.00623
6159_2Pain type(s) experienced in last month: Facial painUK Biobank (UKBB)Neale Lab201865993537923Liver: p = 6.07E-4
Esophagus - Mucosa: p = 0.00619
Prostate: p = 0.03
6159_6Pain type(s) experienced in last month: Hip painUK Biobank (UKBB)Neale Lab2018405003198915Brain - Caudate (basal ganglia): p = 3.43E-5
Brain - Cerebellar Hemisphere: p = 5.53E-5
Brain - Putamen (basal ganglia): p = 8.81E-5
6159_8Pain type(s) experienced in last month: Pain all over the bodyUK Biobank (UKBB)Neale Lab201855303548613Adrenal Gland: p = 0.00752
Esophagus - Muscularis: p = 0.02
Brain - Frontal Cortex (BA9): p = 0.02
6160_100Leisure/social activities: None of the aboveUK Biobank (UKBB)Neale Lab20181087042513595Brain - Amygdala: p = 7.3E-6
Brain - Putamen (basal ganglia): p = 1.85E-5
Brain - Anterior cingulate cortex (BA24): p = 2.9E-5
6160_2Leisure/social activities: Pub or social clubUK Biobank (UKBB)Neale Lab2018984992615644Brain - Cerebellum: p = 3.57E-5
Brain - Substantia nigra: p = 6.53E-5
Brain - Amygdala: p = 8.54E-5
6160_3Leisure/social activities: Religious groupUK Biobank (UKBB)Neale Lab2018526973073664Brain - Nucleus accumbens (basal ganglia): p = 0.00472
Brain - Caudate (basal ganglia): p = 0.00714
Brain - Frontal Cortex (BA9): p = 0.00714
6160_1Leisure/social activities: Sports club or gymUK Biobank (UKBB)Neale Lab20181084732515905Brain - Amygdala: p = 4.37E-4
Spleen: p = 0.00105
Brain - Caudate (basal ganglia): p = 0.00136
6160_5Leisure/social activities: Other group activityUK Biobank (UKBB)Neale Lab2018801782798854Brain - Putamen (basal ganglia): p = 6.55E-6
Brain - Caudate (basal ganglia): p = 1.1E-5
Brain - Spinal cord (cervical c-1): p = 1.22E-4
6160_4Leisure/social activities: Adult education classUK Biobank (UKBB)Neale Lab2018258423342215Muscle - Skeletal: p = 0.04
Colon - Sigmoid: p = 0.05
Pancreas: p = 0.07
6162_1Types of transport used (excluding work): Car/motor vehicleUK Biobank (UKBB)Neale Lab2018285459738654Brain - Substantia nigra: p = 0.00395
Muscle - Skeletal: p = 0.00558
Brain - Amygdala: p = 0.01
6162_3Types of transport used (excluding work): Public transportUK Biobank (UKBB)Neale Lab20181077272515974Brain - Hippocampus: p = 4.22E-4
Brain - Hypothalamus: p = 4.22E-4
Adrenal Gland: p = 0.00124
6162_2Types of transport used (excluding work): WalkUK Biobank (UKBB)Neale Lab20181769341823904Brain - Hypothalamus: p = 8.43E-4
Muscle - Skeletal: p = 8.43E-4
Brain - Anterior cingulate cortex (BA24): p = 0.00172
6162_4Types of transport used (excluding work): CycleUK Biobank (UKBB)Neale Lab2018260593332655Brain - Cortex: p = 2.14E-4
Brain - Cerebellar Hemisphere: p = 5.1E-4
Brain - Cerebellum: p = 5.1E-4
6162_100Types of transport used (excluding work): None of the aboveUK Biobank (UKBB)Neale Lab20187953585293Artery - Aorta: p = 0.01
Kidney - Cortex: p = 0.01
Skin - Sun Exposed (Lower leg): p = 0.02
6164_1Types of physical activity in last 4 weeks: Walking for pleasure (not as a means of transport)UK Biobank (UKBB)Neale Lab20182585741006894Brain - Cortex: p = 1.59E-5
Brain - Anterior cingulate cortex (BA24): p = 5.25E-5
Brain - Nucleus accumbens (basal ganglia): p = 9.32E-5
6164_100Types of physical activity in last 4 weeks: None of the aboveUK Biobank (UKBB)Neale Lab2018212553380085Brain - Cortex: p = 6.98E-6
Brain - Caudate (basal ganglia): p = 1.88E-5
Brain - Hippocampus: p = 4.85E-5
6164_2Types of physical activity in last 4 weeks: Other exercises (eg: swimming, cycling, keep fit, bowling)UK Biobank (UKBB)Neale Lab20181742421850214Brain - Cortex: p = 6.44E-6
Brain - Amygdala: p = 2.1E-5
Brain - Frontal Cortex (BA9): p = 2.1E-5
6164_5Types of physical activity in last 4 weeks: Heavy DIY (eg: weeding, lawn mowing, carpentry, digging)UK Biobank (UKBB)Neale Lab20181565972026664Brain - Hippocampus: p = 8.26E-5
Brain - Anterior cingulate cortex (BA24): p = 1.58E-4
Brain - Cortex: p = 2.94E-4
6164_4Types of physical activity in last 4 weeks: Light DIY (eg: pruning, watering the lawn)UK Biobank (UKBB)Neale Lab20181866791725845Esophagus - Gastroesophageal Junction: p = 5.43E-6
Esophagus - Muscularis: p = 4.13E-5
Colon - Sigmoid: p = 1.11E-4
6164_3Types of physical activity in last 4 weeks: Strenuous sportsUK Biobank (UKBB)Neale Lab2018372973219665Esophagus - Gastroesophageal Junction: p = 4.59E-5
Uterus: p = 2.64E-4
Esophagus - Muscularis: p = 0.00128
6177_2Medication for cholesterol, blood pressure or diabetes: Blood pressure medicationUK Biobank (UKBB)Neale Lab2018409871243534Prostate: p = 9.59E-6
Uterus: p = 0.00282
Kidney - Cortex: p = 0.00629
6177_100Medication for cholesterol, blood pressure or diabetes: None of the aboveUK Biobank (UKBB)Neale Lab2018110372549684Liver: p = 2.44E-5
Spleen: p = 8.73E-5
Adipose - Subcutaneous: p = 6.74E-4
6177_1Medication for cholesterol, blood pressure or diabetes: Cholesterol lowering medicationUK Biobank (UKBB)Neale Lab2018380571272834Liver: p = 6.03E-11
Spleen: p = 0.00374
Adipose - Subcutaneous: p = 0.00426
6177_3Medication for cholesterol, blood pressure or diabetes: InsulinUK Biobank (UKBB)Neale Lab201822481630925Spleen: p = 9.12E-7
Lung: p = 1.76E-5
Small Intestine - Terminal Ileum: p = 8.62E-5
6179_3Mineral and other dietary supplements: CalciumUK Biobank (UKBB)Neale Lab2018240263359904Spleen: p = 0.0036
Whole Blood: p = 0.01
Esophagus - Mucosa: p = 0.02
6179_100Mineral and other dietary supplements: None of the aboveUK Biobank (UKBB)Neale Lab20182048101552064Thyroid: p = 0.00398
Lung: p = 0.00579
Colon - Transverse: p = 0.01
6179_1Mineral and other dietary supplements: Fish oil (including cod liver oil)UK Biobank (UKBB)Neale Lab20181141312458854Adrenal Gland: p = 0.00326
Liver: p = 0.03
Stomach: p = 0.03
6179_2Mineral and other dietary supplements: GlucosamineUK Biobank (UKBB)Neale Lab2018702182897984Brain - Frontal Cortex (BA9): p = 0.00642
Brain - Cortex: p = 0.01
Heart - Atrial Appendage: p = 0.01
6179_4Mineral and other dietary supplements: ZincUK Biobank (UKBB)Neale Lab2018144023456144Brain - Cerebellar Hemisphere: p = 0.00311
Brain - Cerebellum: p = 0.00691
Brain - Frontal Cortex (BA9): p = 0.00691
6179_5Mineral and other dietary supplements: IronUK Biobank (UKBB)Neale Lab2018106953493213Lung: p = 0.01
Uterus: p = 0.03
Pancreas: p = 0.04
6179_6Mineral and other dietary supplements: SeleniumUK Biobank (UKBB)Neale Lab201885183514983Thyroid: p = 0.00711
Skin - Not Sun Exposed (Suprapubic): p = 0.01
Skin - Sun Exposed (Lower leg): p = 0.03
20001_1060Cancer code, self-reported: non-melanoma skin cancerUK Biobank (UKBB)Neale Lab20185423605993Colon - Sigmoid: p = 0.02
Prostate: p = 0.06
Stomach: p = 0.08
20001_1018Cancer code, self-reported: stomach cancerUK Biobank (UKBB)Neale Lab20181333610083Pituitary: p = 2.65E-5
Breast - Mammary Tissue: p = 0.00229
Ovary: p = 0.03
20001_1059Cancer code, self-reported: malignant melanomaUK Biobank (UKBB)Neale Lab201828983582435Pituitary: p = 1.69E-4
Nerve - Tibial: p = 0.00507
Minor Salivary Gland: p = 0.02
20001_1061Cancer code, self-reported: basal cell carcinomaUK Biobank (UKBB)Neale Lab201834413577005Spleen: p = 0.00101
Small Intestine - Terminal Ileum: p = 0.00168
Lung: p = 0.00636
20001_1035Cancer code, self-reported: bladder cancerUK Biobank (UKBB)Neale Lab20188433602983Esophagus - Mucosa: p = 0.0027
Adrenal Gland: p = 0.02
Ovary: p = 0.04
20001_1052Cancer code, self-reported: hodgkins lymphoma / hodgkins diseaseUK Biobank (UKBB)Neale Lab20183603607813Lung: p = 2.62E-5
Spleen: p = 0.00843
Muscle - Skeletal: p = 0.01
20001_1062Cancer code, self-reported: squamous cell carcinomaUK Biobank (UKBB)Neale Lab20184493606923Brain - Spinal cord (cervical c-1): p = 0.00608
Adrenal Gland: p = 0.00853
Brain - Cerebellar Hemisphere: p = 0.00932
20001_1073Cancer code, self-reported: rodent ulcerUK Biobank (UKBB)Neale Lab20185193606223Esophagus - Mucosa: p = 1.52E-4
Vagina: p = 0.02
Minor Salivary Gland: p = 0.03
20001_1022Cancer code, self-reported: colon cancer/sigmoid cancerUK Biobank (UKBB)Neale Lab201812143599273Breast - Mammary Tissue: p = 0.01
Adipose - Subcutaneous: p = 0.02
Whole Blood: p = 0.03
20001_1003Cancer code, self-reported: skin cancerUK Biobank (UKBB)Neale Lab201811253600163Pituitary: p = 0.00472
Adipose - Visceral (Omentum): p = 0.01
Skin - Sun Exposed (Lower leg): p = 0.01
20001_1001Cancer code, self-reported: lung cancerUK Biobank (UKBB)Neale Lab20182033609382Stomach: p = 0.00404
Kidney - Cortex: p = 0.02
Pancreas: p = 0.02
20001_1019Cancer code, self-reported: small intestine/small bowel cancerUK Biobank (UKBB)Neale Lab20181633609783Brain - Spinal cord (cervical c-1): p = 0.01
Liver: p = 0.03
Ovary: p = 0.03
20001_1053Cancer code, self-reported: non-hodgkins lymphomaUK Biobank (UKBB)Neale Lab20186843604573Small Intestine - Terminal Ileum: p = 3.21E-4
Artery - Tibial: p = 0.01
Lung: p = 0.08
20001_1006Cancer code, self-reported: larynx/throat cancerUK Biobank (UKBB)Neale Lab20182813608603Esophagus - Mucosa: p = 0.00148
Muscle - Skeletal: p = 0.00148
Esophagus - Muscularis: p = 0.00792
20001_1020Cancer code, self-reported: large bowel cancer/colorectal cancerUK Biobank (UKBB)Neale Lab20185103606313Kidney - Cortex: p = 0.00295
Adipose - Visceral (Omentum): p = 0.00658
Skin - Sun Exposed (Lower leg): p = 0.01
20001_1050Cancer code, self-reported: multiple myelomaUK Biobank (UKBB)Neale Lab20181253610163Prostate: p = 0.00862
Adipose - Visceral (Omentum): p = 0.04
Heart - Atrial Appendage: p = 0.06
20001_1048Cancer code, self-reported: leukaemiaUK Biobank (UKBB)Neale Lab20181693609723Adrenal Gland: p = 0.00678
Spleen: p = 0.01
Vagina: p = 0.02
20001_1030Cancer code, self-reported: eye and/or adnexal cancerUK Biobank (UKBB)Neale Lab20181093610323Brain - Cerebellar Hemisphere: p = 0.00603
Brain - Cerebellum: p = 0.01
Colon - Transverse: p = 0.05
20001_1032Cancer code, self-reported: brain cancer / primary malignant brain tumourUK Biobank (UKBB)Neale Lab20181723609693Muscle - Skeletal: p = 0.02
Lung: p = 0.02
Artery - Aorta: p = 0.04
20001_99999Cancer code, self-reported: unclassifiableUK Biobank (UKBB)Neale Lab20184053607363Kidney - Cortex: p = 0.00868
Brain - Cerebellum: p = 0.02
Skin - Sun Exposed (Lower leg): p = 0.03
20001_1034Cancer code, self-reported: kidney/renal cell cancerUK Biobank (UKBB)Neale Lab20184733606683Stomach: p = 7.65E-5
Colon - Sigmoid: p = 4.18E-4
Esophagus - Gastroesophageal Junction: p = 0.00319
20001_1068Cancer code, self-reported: sarcoma/fibrosarcomaUK Biobank (UKBB)Neale Lab20181963609452Stomach: p = 0.00102
Skin - Sun Exposed (Lower leg): p = 0.04
Artery - Tibial: p = 0.07
20001_1017Cancer code, self-reported: oesophageal cancerUK Biobank (UKBB)Neale Lab20181623609793Skin - Not Sun Exposed (Suprapubic): p = 6.07E-4
Skin - Sun Exposed (Lower leg): p = 6.07E-4
Whole Blood: p = 0.0027
20001_1055Cancer code, self-reported: chronic lymphocyticUK Biobank (UKBB)Neale Lab20182373609043Lung: p = 6.3E-5
Spleen: p = 0.0047
Whole Blood: p = 0.03
20001_1065Cancer code, self-reported: thyroid cancerUK Biobank (UKBB)Neale Lab20183393608023Colon - Transverse: p = 0.01
Thyroid: p = 0.04
Artery - Coronary: p = 0.04
20001_1063Cancer code, self-reported: primary bone cancerUK Biobank (UKBB)Neale Lab20181113610303Colon - Transverse: p = 9.19E-4
Uterus: p = 0.02
Small Intestine - Terminal Ileum: p = 0.02
20001_1023Cancer code, self-reported: rectal cancerUK Biobank (UKBB)Neale Lab20182723608692Adrenal Gland: p = 0.03
Small Intestine - Terminal Ileum: p = 0.04
Pancreas: p = 0.05
20001_1011Cancer code, self-reported: tongue cancerUK Biobank (UKBB)Neale Lab20181233610182Muscle - Skeletal: p = 0.03
Artery - Coronary: p = 0.04
Colon - Sigmoid: p = 0.04
20001_1024Cancer code, self-reported: liver/hepatocellular cancerUK Biobank (UKBB)Neale Lab20181383610032Lung: p = 0.00813
Muscle - Skeletal: p = 0.02
Adrenal Gland: p = 0.06
20002_1485Non-cancer illness code, self-reported: irregular heart beatUK Biobank (UKBB)Neale Lab20185653605763Muscle - Skeletal: p = 0.00411
Whole Blood: p = 0.02
Colon - Sigmoid: p = 0.08
20002_1065Non-cancer illness code, self-reported: hypertensionUK Biobank (UKBB)Neale Lab2018935602675813Uterus: p = 4.07E-5
Artery - Tibial: p = 0.00154
Heart - Atrial Appendage: p = 0.00691
20002_1456Non-cancer illness code, self-reported: malabsorption/coeliac diseaseUK Biobank (UKBB)Neale Lab201815873595545Spleen: p = 1.01E-12
Lung: p = 1.35E-7
Whole Blood: p = 1.35E-7
20002_1113Non-cancer illness code, self-reported: emphysema/chronic bronchitisUK Biobank (UKBB)Neale Lab201850313561103Muscle - Skeletal: p = 0.00312
Brain - Nucleus accumbens (basal ganglia): p = 0.00523
Brain - Caudate (basal ganglia): p = 0.01
20002_1452Non-cancer illness code, self-reported: eczema/dermatitisUK Biobank (UKBB)Neale Lab201893213518205Whole Blood: p = 6.61E-7
Lung: p = 4.61E-6
Spleen: p = 4.61E-6
20002_1111Non-cancer illness code, self-reported: asthmaUK Biobank (UKBB)Neale Lab2018419343192074Whole Blood: p = 6.52E-9
Spleen: p = 9.06E-7
Esophagus - Gastroesophageal Junction: p = 2.16E-4
20002_1136Non-cancer illness code, self-reported: liver/biliary/pancreas problemUK Biobank (UKBB)Neale Lab20186353605063Liver: p = 1.76E-4
Lung: p = 0.03
Brain - Hippocampus: p = 0.08
20002_1311Non-cancer illness code, self-reported: spine arthritis/spondylitisUK Biobank (UKBB)Neale Lab201831543579873Kidney - Cortex: p = 0.00696
Brain - Cortex: p = 0.02
Liver: p = 0.02
20002_1226Non-cancer illness code, self-reported: hypothyroidism/myxoedemaUK Biobank (UKBB)Neale Lab2018175743435674Spleen: p = 1.38E-14
Whole Blood: p = 2.0E-12
Small Intestine - Terminal Ileum: p = 1.69E-7
20002_1473Non-cancer illness code, self-reported: high cholesterolUK Biobank (UKBB)Neale Lab2018439573171844Liver: p = 2.77E-12
Spleen: p = 0.00108
Adipose - Subcutaneous: p = 0.00243
20002_1223Non-cancer illness code, self-reported: type 2 diabetesUK Biobank (UKBB)Neale Lab201822923588493Breast - Mammary Tissue: p = 0.00177
Esophagus - Gastroesophageal Junction: p = 0.00238
Pancreas: p = 0.00556
20002_1078Non-cancer illness code, self-reported: heart valve problem/heart murmurUK Biobank (UKBB)Neale Lab201824533586883Pancreas: p = 0.02
Skin - Sun Exposed (Lower leg): p = 0.03
Small Intestine - Terminal Ileum: p = 0.05
20002_1075Non-cancer illness code, self-reported: heart attack/myocardial infarctionUK Biobank (UKBB)Neale Lab201882393529025Esophagus - Gastroesophageal Junction: p = 6.92E-6
Esophagus - Muscularis: p = 6.92E-6
Artery - Tibial: p = 7.41E-5
20002_1668Non-cancer illness code, self-reported: allergy to house dust miteUK Biobank (UKBB)Neale Lab20182013609403Adipose - Visceral (Omentum): p = 0.00243
Breast - Mammary Tissue: p = 0.03
Thyroid: p = 0.03
20002_1220Non-cancer illness code, self-reported: diabetesUK Biobank (UKBB)Neale Lab2018141143470274Lung: p = 5.97E-5
Spleen: p = 5.97E-5
Pancreas: p = 6.36E-4
20002_1286Non-cancer illness code, self-reported: depressionUK Biobank (UKBB)Neale Lab2018206483404933Prostate: p = 0.01
Artery - Tibial: p = 0.01
Brain - Anterior cingulate cortex (BA24): p = 0.04
20002_1265Non-cancer illness code, self-reported: migraineUK Biobank (UKBB)Neale Lab2018106473504945Artery - Tibial: p = 4.89E-4
Artery - Aorta: p = 0.00141
Artery - Coronary: p = 0.00163
20002_1561Non-cancer illness code, self-reported: raynaud's phenomenon/diseaseUK Biobank (UKBB)Neale Lab20183753607663Pancreas: p = 3.38E-4
Breast - Mammary Tissue: p = 0.00874
Stomach: p = 0.01
20002_1374Non-cancer illness code, self-reported: allergy/hypersensitivity/anaphylaxisUK Biobank (UKBB)Neale Lab201826223585193Testis: p = 0.00381
Lung: p = 0.00761
Vagina: p = 0.02
20002_1398Non-cancer illness code, self-reported: pneumoniaUK Biobank (UKBB)Neale Lab201851823559592Nerve - Tibial: p = 0.00909
Adipose - Visceral (Omentum): p = 0.01
Adipose - Subcutaneous: p = 0.04
20002_1261Non-cancer illness code, self-reported: multiple sclerosisUK Biobank (UKBB)Neale Lab201813263598155Spleen: p = 9.93E-8
Whole Blood: p = 3.05E-6
Lung: p = 7.75E-6
20002_1466Non-cancer illness code, self-reported: goutUK Biobank (UKBB)Neale Lab201851743559675Liver: p = 0.00149
Kidney - Cortex: p = 0.00153
Spleen: p = 0.00306
20002_1117Non-cancer illness code, self-reported: other respiratory problemsUK Biobank (UKBB)Neale Lab20186283605132Spleen: p = 0.00344
Heart - Atrial Appendage: p = 0.00562
Heart - Left Ventricle: p = 0.01
20002_1465Non-cancer illness code, self-reported: osteoarthritisUK Biobank (UKBB)Neale Lab2018300463310954Artery - Aorta: p = 1.44E-4
Muscle - Skeletal: p = 0.00166
Brain - Cerebellar Hemisphere: p = 0.00178
20002_1074Non-cancer illness code, self-reported: anginaUK Biobank (UKBB)Neale Lab2018113703497715Artery - Coronary: p = 0.00122
Liver: p = 0.00824
Uterus: p = 0.009
20002_1222Non-cancer illness code, self-reported: type 1 diabetesUK Biobank (UKBB)Neale Lab20183183608235Spleen: p = 9.81E-7
Lung: p = 5.35E-6
Whole Blood: p = 2.31E-4
20002_1463Non-cancer illness code, self-reported: ulcerative colitisUK Biobank (UKBB)Neale Lab201819163592255Spleen: p = 1.39E-6
Lung: p = 4.94E-5
Whole Blood: p = 1.01E-4
20002_1387Non-cancer illness code, self-reported: hayfever/allergic rhinitisUK Biobank (UKBB)Neale Lab2018206673404745Whole Blood: p = 1.36E-6
Lung: p = 9.09E-6
Spleen: p = 5.31E-4
20002_1439Non-cancer illness code, self-reported: hiv/aidsUK Biobank (UKBB)Neale Lab20182853608563Breast - Mammary Tissue: p = 3.98E-4
Prostate: p = 0.00943
Esophagus - Gastroesophageal Junction: p = 0.02
20002_1474Non-cancer illness code, self-reported: hiatus herniaUK Biobank (UKBB)Neale Lab201883403528013Spleen: p = 0.00639
Uterus: p = 0.00942
Whole Blood: p = 0.03
20002_1471Non-cancer illness code, self-reported: atrial fibrillationUK Biobank (UKBB)Neale Lab201828283583135Heart - Atrial Appendage: p = 0.00137
Colon - Sigmoid: p = 0.00277
Heart - Left Ventricle: p = 0.00277
20002_1478Non-cancer illness code, self-reported: cervical spondylosisUK Biobank (UKBB)Neale Lab201825103586313Skin - Sun Exposed (Lower leg): p = 8.17E-5
Skin - Not Sun Exposed (Suprapubic): p = 1.79E-4
Vagina: p = 0.03
20002_1453Non-cancer illness code, self-reported: psoriasisUK Biobank (UKBB)Neale Lab201841923569495Lung: p = 3.3E-7
Spleen: p = 3.3E-7
Whole Blood: p = 1.7E-6
20002_1197Non-cancer illness code, self-reported: kidney stone/ureter stone/bladder stoneUK Biobank (UKBB)Neale Lab201828633582784Kidney - Cortex: p = 2.06E-5
Esophagus - Mucosa: p = 0.0015
Artery - Coronary: p = 0.03
20002_1162Non-cancer illness code, self-reported: cholelithiasis/gall stonesUK Biobank (UKBB)Neale Lab201859413552005Liver: p = 1.9E-5
Stomach: p = 0.00612
Esophagus - Mucosa: p = 0.02
20002_1247Non-cancer illness code, self-reported: meningitisUK Biobank (UKBB)Neale Lab201815153596263Minor Salivary Gland: p = 9.48E-4
Adipose - Subcutaneous: p = 0.03
Prostate: p = 0.08
20002_99999Non-cancer illness code, self-reported: unclassifiableUK Biobank (UKBB)Neale Lab2018145973465443Skin - Not Sun Exposed (Suprapubic): p = 0.00134
Skin - Sun Exposed (Lower leg): p = 0.00217
Spleen: p = 0.00217
20002_1470Non-cancer illness code, self-reported: anorexia/bulimia/other eating disorderUK Biobank (UKBB)Neale Lab20182903608513Spleen: p = 0.00308
Stomach: p = 0.00682
Heart - Atrial Appendage: p = 0.02
20002_1093Non-cancer illness code, self-reported: pulmonary embolism +/- dvtUK Biobank (UKBB)Neale Lab201829993581425Liver: p = 3.43E-6
Stomach: p = 9.22E-6
Pancreas: p = 2.56E-4
20002_1382Non-cancer illness code, self-reported: sjogren's syndrome/sicca syndromeUK Biobank (UKBB)Neale Lab20183383608035Spleen: p = 1.49E-6
Lung: p = 3.02E-4
Whole Blood: p = 0.00281
20002_1294Non-cancer illness code, self-reported: back problemUK Biobank (UKBB)Neale Lab201863393548023Brain - Cerebellar Hemisphere: p = 0.01
Brain - Cerebellum: p = 0.01
Minor Salivary Gland: p = 0.02
20002_1094Non-cancer illness code, self-reported: deep venous thrombosis (dvt)UK Biobank (UKBB)Neale Lab201872373539045Liver: p = 6.52E-5
Esophagus - Gastroesophageal Junction: p = 0.00116
Stomach: p = 0.00116
20002_1264Non-cancer illness code, self-reported: epilepsyUK Biobank (UKBB)Neale Lab201830153581263Brain - Anterior cingulate cortex (BA24): p = 0.00352
Brain - Cortex: p = 0.00843
Brain - Frontal Cortex (BA9): p = 0.00843
20002_1599Non-cancer illness code, self-reported: constipationUK Biobank (UKBB)Neale Lab20182863608553Stomach: p = 0.01
Uterus: p = 0.02
Adipose - Visceral (Omentum): p = 0.03
20002_1458Non-cancer illness code, self-reported: diverticular disease/diverticulitisUK Biobank (UKBB)Neale Lab201841243570173Esophagus - Gastroesophageal Junction: p = 2.47E-4
Esophagus - Muscularis: p = 0.00158
Colon - Sigmoid: p = 0.00242
20002_1201Non-cancer illness code, self-reported: bladder problem (not cancer)UK Biobank (UKBB)Neale Lab201821403590013Esophagus - Mucosa: p = 9.94E-5
Minor Salivary Gland: p = 0.00142
Lung: p = 0.00761
20002_1385Non-cancer illness code, self-reported: allergy or anaphylactic reaction to foodUK Biobank (UKBB)Neale Lab201816213595203Skin - Not Sun Exposed (Suprapubic): p = 0.02
Brain - Cortex: p = 0.02
Vagina: p = 0.02
20002_1081Non-cancer illness code, self-reported: strokeUK Biobank (UKBB)Neale Lab201848363563053Pituitary: p = 0.00597
Muscle - Skeletal: p = 0.02
Nerve - Tibial: p = 0.02
20002_1257Non-cancer illness code, self-reported: trapped nerve/compressed nerveUK Biobank (UKBB)Neale Lab201810733600683Small Intestine - Terminal Ileum: p = 0.01
Esophagus - Mucosa: p = 0.01
Vagina: p = 0.05
20002_1460Non-cancer illness code, self-reported: rectal or colon adenoma/polypsUK Biobank (UKBB)Neale Lab201810883600532Skin - Not Sun Exposed (Suprapubic): p = 1.23E-4
Skin - Sun Exposed (Lower leg): p = 4.08E-4
Heart - Atrial Appendage: p = 0.00184
20002_1651Non-cancer illness code, self-reported: fracture lower leg / ankleUK Biobank (UKBB)Neale Lab201814713596703Vagina: p = 0.00688
Brain - Cerebellum: p = 0.01
Brain - Cerebellar Hemisphere: p = 0.02
20002_1500Non-cancer illness code, self-reported: vertigoUK Biobank (UKBB)Neale Lab20184313607103Adrenal Gland: p = 4.73E-4
Nerve - Tibial: p = 0.01
Brain - Spinal cord (cervical c-1): p = 0.04
20002_1416Non-cancer illness code, self-reported: chronic sinusitisUK Biobank (UKBB)Neale Lab201822573588843Pancreas: p = 0.03
Spleen: p = 0.03
Esophagus - Gastroesophageal Junction: p = 0.04
20002_1476Non-cancer illness code, self-reported: sciaticaUK Biobank (UKBB)Neale Lab201834003577413Liver: p = 8.41E-4
Thyroid: p = 0.04
Pituitary: p = 0.07
20002_1154Non-cancer illness code, self-reported: irritable bowel syndromeUK Biobank (UKBB)Neale Lab201885373526044Lung: p = 0.00135
Liver: p = 0.00209
Uterus: p = 0.00278
20002_1312Non-cancer illness code, self-reported: prolapsed disc/slipped discUK Biobank (UKBB)Neale Lab201860063551354Vagina: p = 4.22E-4
Whole Blood: p = 0.00149
Prostate: p = 0.00414
20002_1331Non-cancer illness code, self-reported: pernicious anaemiaUK Biobank (UKBB)Neale Lab201811093600323Uterus: p = 0.00256
Small Intestine - Terminal Ileum: p = 0.00331
Lung: p = 0.00333
20002_1400Non-cancer illness code, self-reported: peptic ulcerUK Biobank (UKBB)Neale Lab20183813607603Testis: p = 6.07E-4
Adipose - Subcutaneous: p = 0.0088
Brain - Cerebellum: p = 0.02
20002_1242Non-cancer illness code, self-reported: eye/eyelid problemUK Biobank (UKBB)Neale Lab201828403583013Nerve - Tibial: p = 0.02
Skin - Sun Exposed (Lower leg): p = 0.03
Whole Blood: p = 0.03
20002_1138Non-cancer illness code, self-reported: gastro-oesophageal reflux (gord) / gastric refluxUK Biobank (UKBB)Neale Lab2018152103459313Stomach: p = 0.00184
Esophagus - Gastroesophageal Junction: p = 0.00356
Lung: p = 0.00356
20002_1313Non-cancer illness code, self-reported: ankylosing spondylitisUK Biobank (UKBB)Neale Lab201810383601035Spleen: p = 1.18E-5
Lung: p = 1.76E-5
Whole Blood: p = 1.76E-5
20002_1377Non-cancer illness code, self-reported: polymyalgia rheumaticaUK Biobank (UKBB)Neale Lab20187533603885Lung: p = 4.41E-8
Spleen: p = 4.02E-6
Whole Blood: p = 2.03E-4
20002_1504Non-cancer illness code, self-reported: anal fissureUK Biobank (UKBB)Neale Lab20181883609533Adrenal Gland: p = 0.00153
Minor Salivary Gland: p = 0.01
Stomach: p = 0.03
20002_1275Non-cancer illness code, self-reported: retinal problemUK Biobank (UKBB)Neale Lab20186313605103Colon - Sigmoid: p = 0.00998
Pituitary: p = 0.02
Heart - Left Ventricle: p = 0.03
20002_1598Non-cancer illness code, self-reported: tonsiltisUK Biobank (UKBB)Neale Lab201825693585723Breast - Mammary Tissue: p = 0.00502
Adipose - Visceral (Omentum): p = 0.01
Thyroid: p = 0.01
20002_1421Non-cancer illness code, self-reported: meniere's diseaseUK Biobank (UKBB)Neale Lab201810313601103Artery - Coronary: p = 0.00164
Thyroid: p = 0.00227
Artery - Aorta: p = 0.01
20002_1165Non-cancer illness code, self-reported: pancreatitisUK Biobank (UKBB)Neale Lab20187773603643Lung: p = 8.61E-4
Vagina: p = 0.00321
Esophagus - Mucosa: p = 0.02
20002_1156Non-cancer illness code, self-reported: infective/viral hepatitisUK Biobank (UKBB)Neale Lab20187683603733Brain - Cerebellum: p = 0.02
Skin - Sun Exposed (Lower leg): p = 0.05
Small Intestine - Terminal Ileum: p = 0.07
20002_1608Non-cancer illness code, self-reported: nephritisUK Biobank (UKBB)Neale Lab20181153610262Breast - Mammary Tissue: p = 2.56E-4
Adipose - Subcutaneous: p = 0.00626
Adipose - Visceral (Omentum): p = 0.01
20002_1461Non-cancer illness code, self-reported: inflammatory bowel diseaseUK Biobank (UKBB)Neale Lab20181503609913Skin - Sun Exposed (Lower leg): p = 9.51E-5
Skin - Not Sun Exposed (Suprapubic): p = 1.72E-4
Brain - Substantia nigra: p = 0.00152
20002_1677Non-cancer illness code, self-reported: scarlet fever / scarlatinaUK Biobank (UKBB)Neale Lab20184353607063Artery - Aorta: p = 0.03
Artery - Tibial: p = 0.03
Esophagus - Mucosa: p = 0.05
20002_1533Non-cancer illness code, self-reported: disc degenerationUK Biobank (UKBB)Neale Lab20186673604742Brain - Cortex: p = 2.12E-4
Ovary: p = 6.18E-4
Brain - Amygdala: p = 0.00169
20002_1462Non-cancer illness code, self-reported: Crohn's diseaseUK Biobank (UKBB)Neale Lab201810963600454Whole Blood: p = 7.95E-5
Spleen: p = 1.68E-4
Skin - Not Sun Exposed (Suprapubic): p = 0.02
20002_1067Non-cancer illness code, self-reported: peripheral vascular diseaseUK Biobank (UKBB)Neale Lab20186643604773Pancreas: p = 0.00222
Esophagus - Gastroesophageal Junction: p = 0.00564
Esophagus - Muscularis: p = 0.00564
20002_1457Non-cancer illness code, self-reported: duodenal ulcerUK Biobank (UKBB)Neale Lab201814993596423Esophagus - Mucosa: p = 4.82E-4
Vagina: p = 0.00115
Stomach: p = 0.02
20002_1494Non-cancer illness code, self-reported: varicose veinsUK Biobank (UKBB)Neale Lab201812993598423Esophagus - Gastroesophageal Junction: p = 6.3E-5
Esophagus - Muscularis: p = 6.3E-5
Colon - Sigmoid: p = 0.0027
20002_1163Non-cancer illness code, self-reported: cholecystitisUK Biobank (UKBB)Neale Lab20183813607603Lung: p = 0.00113
Spleen: p = 0.00634
Liver: p = 0.02
20002_1405Non-cancer illness code, self-reported: other renal/kidney problemUK Biobank (UKBB)Neale Lab201815043596373Stomach: p = 0.00929
Whole Blood: p = 0.00929
Spleen: p = 0.02
20002_1287Non-cancer illness code, self-reported: anxiety/panic attacksUK Biobank (UKBB)Neale Lab201849613561803Adipose - Subcutaneous: p = 0.02
Adipose - Visceral (Omentum): p = 0.03
Brain - Caudate (basal ganglia): p = 0.03
20002_1126Non-cancer illness code, self-reported: spontaneous pneumothorax/recurrent pneumothoraxUK Biobank (UKBB)Neale Lab20188713602702Prostate: p = 0.02
Testis: p = 0.02
Whole Blood: p = 0.02
20002_1135Non-cancer illness code, self-reported: stomach disorderUK Biobank (UKBB)Neale Lab20187793603623Esophagus - Muscularis: p = 0.00426
Minor Salivary Gland: p = 0.00671
Ovary: p = 0.01
20002_1436Non-cancer illness code, self-reported: headaches (not migraine)UK Biobank (UKBB)Neale Lab201830223581193Brain - Cerebellar Hemisphere: p = 0.00841
Brain - Cerebellum: p = 0.00841
Heart - Atrial Appendage: p = 0.00993
20002_1225Non-cancer illness code, self-reported: hyperthyroidism/thyrotoxicosisUK Biobank (UKBB)Neale Lab201827303584115Spleen: p = 2.18E-11
Lung: p = 3.39E-6
Whole Blood: p = 3.21E-5
20002_1309Non-cancer illness code, self-reported: osteoporosisUK Biobank (UKBB)Neale Lab201857363554054Artery - Aorta: p = 0.01
Artery - Tibial: p = 0.01
Thyroid: p = 0.02
20002_1330Non-cancer illness code, self-reported: iron deficiency anaemiaUK Biobank (UKBB)Neale Lab201819883591533Lung: p = 0.00727
Minor Salivary Gland: p = 0.01
Esophagus - Muscularis: p = 0.02
20002_1614Non-cancer illness code, self-reported: stressUK Biobank (UKBB)Neale Lab20184283607132Vagina: p = 0.03
Esophagus - Muscularis: p = 0.06
Brain - Frontal Cortex (BA9): p = 0.07
20002_1623Non-cancer illness code, self-reported: tennis elbow / lateral epicondylitisUK Biobank (UKBB)Neale Lab20181913609503Whole Blood: p = 0.01
Breast - Mammary Tissue: p = 0.03
Thyroid: p = 0.03
20002_1502Non-cancer illness code, self-reported: appendicitisUK Biobank (UKBB)Neale Lab201830583580832Colon - Sigmoid: p = 1.15E-4
Esophagus - Gastroesophageal Junction: p = 0.00562
Esophagus - Muscularis: p = 0.00846
20002_1297Non-cancer illness code, self-reported: muscle/soft tissue problemUK Biobank (UKBB)Neale Lab201828623582792Lung: p = 0.00929
Artery - Aorta: p = 0.03
Liver: p = 0.06
20002_1291Non-cancer illness code, self-reported: mania/bipolar disorder/manic depressionUK Biobank (UKBB)Neale Lab201810083601333Adipose - Visceral (Omentum): p = 0.00559
Adipose - Subcutaneous: p = 0.01
Liver: p = 0.01
20002_1415Non-cancer illness code, self-reported: ear/vestibular disorderUK Biobank (UKBB)Neale Lab201831033580383Nerve - Tibial: p = 0.00349
Brain - Cerebellum: p = 0.00707
Minor Salivary Gland: p = 0.01
20002_1467Non-cancer illness code, self-reported: other joint disorderUK Biobank (UKBB)Neale Lab201822763588653Kidney - Cortex: p = 1.56E-4
Skin - Not Sun Exposed (Suprapubic): p = 0.02
Nerve - Tibial: p = 0.02
20002_1646Non-cancer illness code, self-reported: fracture vertebra / crush fracture / vertebral collapseUK Biobank (UKBB)Neale Lab20182753608663Colon - Transverse: p = 0.00696
Small Intestine - Terminal Ileum: p = 0.04
Heart - Left Ventricle: p = 0.04
20002_1407Non-cancer illness code, self-reported: burnsUK Biobank (UKBB)Neale Lab20183383608033Esophagus - Gastroesophageal Junction: p = 0.01
Skin - Sun Exposed (Lower leg): p = 0.02
Artery - Tibial: p = 0.03
20002_1434Non-cancer illness code, self-reported: other neurological problemUK Biobank (UKBB)Neale Lab201815083596333Heart - Left Ventricle: p = 0.03
Brain - Substantia nigra: p = 0.08
Muscle - Skeletal: p = 0.08
20002_1251Non-cancer illness code, self-reported: spinal cord disorderUK Biobank (UKBB)Neale Lab20183623607793Brain - Caudate (basal ganglia): p = 7.88E-4
Brain - Anterior cingulate cortex (BA24): p = 0.00527
Brain - Amygdala: p = 0.01
20002_1295Non-cancer illness code, self-reported: joint disorderUK Biobank (UKBB)Neale Lab201817433593983Heart - Atrial Appendage: p = 0.00145
Artery - Aorta: p = 0.02
Artery - Tibial: p = 0.02
20002_1545Non-cancer illness code, self-reported: neck problem/injuryUK Biobank (UKBB)Neale Lab20183173608242Stomach: p = 0.00733
Vagina: p = 0.02
Pancreas: p = 0.02
20002_1482Non-cancer illness code, self-reported: chronic fatigue syndromeUK Biobank (UKBB)Neale Lab201816593594823Minor Salivary Gland: p = 0.00143
Stomach: p = 0.02
Thyroid: p = 0.03
20002_1157Non-cancer illness code, self-reported: non-infective hepatitisUK Biobank (UKBB)Neale Lab20183743607672Prostate: p = 8.33E-4
Vagina: p = 0.00377
Esophagus - Mucosa: p = 0.00917
20002_1190Non-cancer illness code, self-reported: peritonitisUK Biobank (UKBB)Neale Lab201812613598802Artery - Coronary: p = 0.02
Adipose - Subcutaneous: p = 0.04
Esophagus - Gastroesophageal Junction: p = 0.06
20002_1538Non-cancer illness code, self-reported: arthritis (nos)UK Biobank (UKBB)Neale Lab201827873583542Heart - Left Ventricle: p = 0.03
Adrenal Gland: p = 0.03
Artery - Coronary: p = 0.03
20002_1274Non-cancer illness code, self-reported: eye infectionUK Biobank (UKBB)Neale Lab20183593607823Whole Blood: p = 7.85E-4
Spleen: p = 0.00507
Lung: p = 0.01
20002_1637Non-cancer illness code, self-reported: fracture wrist / colles fractureUK Biobank (UKBB)Neale Lab20188393603023Heart - Left Ventricle: p = 0.005
Adipose - Subcutaneous: p = 0.02
Minor Salivary Gland: p = 0.02
20002_1513Non-cancer illness code, self-reported: inguinal herniaUK Biobank (UKBB)Neale Lab201814973596443Breast - Mammary Tissue: p = 0.00164
Adipose - Visceral (Omentum): p = 0.00901
Brain - Nucleus accumbens (basal ganglia): p = 0.07
20002_1412Non-cancer illness code, self-reported: bronchitisUK Biobank (UKBB)Neale Lab201826813584603Brain - Amygdala: p = 0.03
Skin - Not Sun Exposed (Suprapubic): p = 0.03
Skin - Sun Exposed (Lower leg): p = 0.03
20002_1381Non-cancer illness code, self-reported: systemic lupus erythematosis/sleUK Biobank (UKBB)Neale Lab20184153607265Spleen: p = 3.13E-7
Lung: p = 1.51E-6
Whole Blood: p = 0.00377
20002_1617Non-cancer illness code, self-reported: osteopeniaUK Biobank (UKBB)Neale Lab20188993602423Lung: p = 0.00845
Adrenal Gland: p = 0.01
Heart - Atrial Appendage: p = 0.03
20002_1408Non-cancer illness code, self-reported: alcohol dependencyUK Biobank (UKBB)Neale Lab20185613605803Lung: p = 0.03
Artery - Coronary: p = 0.03
Brain - Putamen (basal ganglia): p = 0.07
20002_1620Non-cancer illness code, self-reported: bursitisUK Biobank (UKBB)Neale Lab20181053610363Brain - Anterior cingulate cortex (BA24): p = 0.09
Brain - Frontal Cortex (BA9): p = 0.09
Brain - Spinal cord (cervical c-1): p = 0.09
20002_1258Non-cancer illness code, self-reported: chronic/degenerative neurological problemUK Biobank (UKBB)Neale Lab20181243610172Artery - Tibial: p = 0.00184
Artery - Aorta: p = 0.00234
Artery - Coronary: p = 0.00385
20002_1464Non-cancer illness code, self-reported: rheumatoid arthritisUK Biobank (UKBB)Neale Lab201840173571245Spleen: p = 1.45E-9
Lung: p = 3.84E-7
Whole Blood: p = 6.21E-5
20002_1066Non-cancer illness code, self-reported: heart/cardiac problemUK Biobank (UKBB)Neale Lab201811763599652Pancreas: p = 0.00712
Stomach: p = 0.00713
Muscle - Skeletal: p = 0.03
20002_1125Non-cancer illness code, self-reported: pleurisyUK Biobank (UKBB)Neale Lab201812203599213Liver: p = 0.00129
Lung: p = 0.00213
Prostate: p = 0.00446
20002_1459Non-cancer illness code, self-reported: colitis/not crohns or ulcerative colitisUK Biobank (UKBB)Neale Lab20189593601823Lung: p = 3.24E-4
Spleen: p = 6.12E-4
Small Intestine - Terminal Ileum: p = 0.02
20002_1282Non-cancer illness code, self-reported: retinal artery/vein occlusionUK Biobank (UKBB)Neale Lab20181723609693Artery - Tibial: p = 0.00384
Artery - Aorta: p = 0.00959
Artery - Coronary: p = 0.02
20002_1293Non-cancer illness code, self-reported: bone disorderUK Biobank (UKBB)Neale Lab20188273603143Colon - Sigmoid: p = 0.00304
Kidney - Cortex: p = 0.00502
Whole Blood: p = 0.01
20002_1224Non-cancer illness code, self-reported: thyroid problem (not cancer)UK Biobank (UKBB)Neale Lab20189593601823Nerve - Tibial: p = 0.02
Muscle - Skeletal: p = 0.05
Kidney - Cortex: p = 0.07
20002_1563Non-cancer illness code, self-reported: urticariaUK Biobank (UKBB)Neale Lab20182293609123Adipose - Subcutaneous: p = 0.00735
Vagina: p = 0.00735
Whole Blood: p = 0.04
20002_1142Non-cancer illness code, self-reported: gastric/stomach ulcersUK Biobank (UKBB)Neale Lab201825623585793Ovary: p = 0.0027
Brain - Cerebellar Hemisphere: p = 0.01
Brain - Frontal Cortex (BA9): p = 0.01
20002_1406Non-cancer illness code, self-reported: muscle or soft tissue injuriesUK Biobank (UKBB)Neale Lab201826533584883Pancreas: p = 0.03
Testis: p = 0.03
Brain - Caudate (basal ganglia): p = 0.03
20002_1629Non-cancer illness code, self-reported: fracture face / orbit / eye socketUK Biobank (UKBB)Neale Lab20181483609932Whole Blood: p = 0.01
Brain - Anterior cingulate cortex (BA24): p = 0.02
Brain - Frontal Cortex (BA9): p = 0.02
20002_1417Non-cancer illness code, self-reported: nasal polypsUK Biobank (UKBB)Neale Lab201815873595544Spleen: p = 9.41E-5
Colon - Sigmoid: p = 2.84E-4
Lung: p = 3.41E-4
20002_1086Non-cancer illness code, self-reported: subarachnoid haemorrhageUK Biobank (UKBB)Neale Lab20183373608043Esophagus - Mucosa: p = 0.01
Artery - Aorta: p = 0.02
Artery - Tibial: p = 0.02
20002_1277Non-cancer illness code, self-reported: glaucomaUK Biobank (UKBB)Neale Lab201837863573555Artery - Coronary: p = 3.15E-6
Esophagus - Gastroesophageal Junction: p = 5.51E-6
Artery - Tibial: p = 9.51E-6
20002_1077Non-cancer illness code, self-reported: heart arrhythmiaUK Biobank (UKBB)Neale Lab201820133591283Esophagus - Mucosa: p = 1.06E-4
Vagina: p = 6.95E-4
Whole Blood: p = 0.02
20002_1657Non-cancer illness code, self-reported: septicaemia / sepsisUK Biobank (UKBB)Neale Lab20182383609032Vagina: p = 0.02
Testis: p = 0.03
Minor Salivary Gland: p = 0.11
20002_1114Non-cancer illness code, self-reported: bronchiectasisUK Biobank (UKBB)Neale Lab20188763602653Lung: p = 0.00181
Brain - Cerebellar Hemisphere: p = 0.00621
Spleen: p = 0.00739
20002_1289Non-cancer illness code, self-reported: schizophreniaUK Biobank (UKBB)Neale Lab20183913607502Uterus: p = 0.02
Ovary: p = 0.02
Adipose - Visceral (Omentum): p = 0.03
20002_1455Non-cancer illness code, self-reported: chronic skin ulcersUK Biobank (UKBB)Neale Lab20181233610183Colon - Transverse: p = 6.07E-4
Small Intestine - Terminal Ileum: p = 0.0054
Prostate: p = 0.01
20002_1530Non-cancer illness code, self-reported: iritisUK Biobank (UKBB)Neale Lab20181553609863Brain - Anterior cingulate cortex (BA24): p = 0.00361
Brain - Hypothalamus: p = 0.01
Brain - Amygdala: p = 0.02
20002_1139Non-cancer illness code, self-reported: oesophagitis/barretts oesophagusUK Biobank (UKBB)Neale Lab201811443599973Colon - Sigmoid: p = 0.0075
Thyroid: p = 0.03
Brain - Cortex: p = 0.03
20002_1112Non-cancer illness code, self-reported: chronic obstructive airways disease/copdUK Biobank (UKBB)Neale Lab201812853598563Artery - Tibial: p = 5.83E-4
Artery - Aorta: p = 0.03
Artery - Coronary: p = 0.06
20002_1082Non-cancer illness code, self-reported: transient ischaemic attack (tia)UK Biobank (UKBB)Neale Lab201813693597723Liver: p = 0.00359
Thyroid: p = 0.00866
Breast - Mammary Tissue: p = 0.02
20002_1202Non-cancer illness code, self-reported: urinary frequency / incontinenceUK Biobank (UKBB)Neale Lab201812523598893Minor Salivary Gland: p = 0.0075
Lung: p = 0.04
Esophagus - Mucosa: p = 0.07
20002_1255Non-cancer illness code, self-reported: peripheral neuropathyUK Biobank (UKBB)Neale Lab20185203606212Skin - Not Sun Exposed (Suprapubic): p = 3.59E-4
Skin - Sun Exposed (Lower leg): p = 3.59E-4
Esophagus - Mucosa: p = 0.00637
20002_1526Non-cancer illness code, self-reported: polio / poliomyelitisUK Biobank (UKBB)Neale Lab20182563608853Whole Blood: p = 0.02
Thyroid: p = 0.03
Small Intestine - Terminal Ileum: p = 0.09
20002_1134Non-cancer illness code, self-reported: oesophageal disorderUK Biobank (UKBB)Neale Lab20182193609223Nerve - Tibial: p = 0.00255
Adipose - Subcutaneous: p = 0.06
Pituitary: p = 0.08
20002_1371Non-cancer illness code, self-reported: sarcoidosisUK Biobank (UKBB)Neale Lab20187053604365Spleen: p = 5.72E-10
Lung: p = 8.51E-6
Whole Blood: p = 4.51E-4
20002_1626Non-cancer illness code, self-reported: fracture skull / headUK Biobank (UKBB)Neale Lab20182683608733Esophagus - Mucosa: p = 0.00118
Thyroid: p = 0.00125
Brain - Cerebellum: p = 0.00619
20002_1572Non-cancer illness code, self-reported: whooping cough / pertussisUK Biobank (UKBB)Neale Lab20184073607343Brain - Cerebellar Hemisphere: p = 0.00488
Nerve - Tibial: p = 0.00702
Muscle - Skeletal: p = 0.01
20002_1472Non-cancer illness code, self-reported: emphysemaUK Biobank (UKBB)Neale Lab20181503609912Breast - Mammary Tissue: p = 0.00917
Adipose - Visceral (Omentum): p = 0.04
Whole Blood: p = 0.05
20002_1266Non-cancer illness code, self-reported: head injuryUK Biobank (UKBB)Neale Lab201812303599113Spleen: p = 0.02
Whole Blood: p = 0.03
Brain - Cerebellum: p = 0.04
20002_1660Non-cancer illness code, self-reported: rosaceaUK Biobank (UKBB)Neale Lab20185853605562Whole Blood: p = 0.03
Kidney - Cortex: p = 0.05
Lung: p = 0.05
20002_1386Non-cancer illness code, self-reported: allergy or anaphylactic reaction to drugUK Biobank (UKBB)Neale Lab201832553578863Brain - Substantia nigra: p = 4.24E-4
Brain - Putamen (basal ganglia): p = 0.00721
Thyroid: p = 0.00838
20002_1542Non-cancer illness code, self-reported: fibromyalgiaUK Biobank (UKBB)Neale Lab20185333606083Brain - Nucleus accumbens (basal ganglia): p = 0.00165
Brain - Cerebellar Hemisphere: p = 0.00429
Brain - Hypothalamus: p = 0.00806
20002_1072Non-cancer illness code, self-reported: essential hypertensionUK Biobank (UKBB)Neale Lab201816583594833Brain - Substantia nigra: p = 0.00392
Heart - Left Ventricle: p = 0.00398
Brain - Hippocampus: p = 0.01
20002_1440Non-cancer illness code, self-reported: tuberculosis (tb)UK Biobank (UKBB)Neale Lab201817683593733Colon - Sigmoid: p = 0.01
Prostate: p = 0.03
Testis: p = 0.04
20002_1479Non-cancer illness code, self-reported: rheumatic feverUK Biobank (UKBB)Neale Lab201810613600803Lung: p = 8.8E-4
Muscle - Skeletal: p = 0.02
Testis: p = 0.02
20002_1639Non-cancer illness code, self-reported: fracture fingerUK Biobank (UKBB)Neale Lab20183983607433Colon - Sigmoid: p = 0.05
Esophagus - Gastroesophageal Junction: p = 0.05
Liver: p = 0.05
20002_1625Non-cancer illness code, self-reported: cellulitisUK Biobank (UKBB)Neale Lab20182323609093Brain - Spinal cord (cervical c-1): p = 0.02
Colon - Sigmoid: p = 0.02
Brain - Putamen (basal ganglia): p = 0.03
20002_1281Non-cancer illness code, self-reported: retinal detachmentUK Biobank (UKBB)Neale Lab201812193599223Artery - Coronary: p = 0.01
Testis: p = 0.02
Artery - Aorta: p = 0.06
20002_1644Non-cancer illness code, self-reported: fracture ribUK Biobank (UKBB)Neale Lab20183683607732Whole Blood: p = 1.2E-4
Brain - Cortex: p = 0.00165
Brain - Anterior cingulate cortex (BA24): p = 0.02
20002_1619Non-cancer illness code, self-reported: tendonitis / tendinitis / tenosynovitisUK Biobank (UKBB)Neale Lab20182163609253Brain - Anterior cingulate cortex (BA24): p = 0.02
Brain - Frontal Cortex (BA9): p = 0.02
Brain - Substantia nigra: p = 0.02
20002_1143Non-cancer illness code, self-reported: gastritis/gastric erosionsUK Biobank (UKBB)Neale Lab20185663605753Liver: p = 0.03
Pancreas: p = 0.05
Whole Blood: p = 0.05
20002_1430Non-cancer illness code, self-reported: hypopituitarismUK Biobank (UKBB)Neale Lab20181333610082Heart - Atrial Appendage: p = 0.00196
Heart - Left Ventricle: p = 0.03
Stomach: p = 0.06
20002_1477Non-cancer illness code, self-reported: psoriatic arthropathyUK Biobank (UKBB)Neale Lab20187123604295Lung: p = 5.25E-8
Spleen: p = 8.15E-8
Whole Blood: p = 1.59E-7
20002_1571Non-cancer illness code, self-reported: chickenpoxUK Biobank (UKBB)Neale Lab201814403597013Whole Blood: p = 4.55E-6
Small Intestine - Terminal Ileum: p = 0.02
Spleen: p = 0.02
20002_1413Non-cancer illness code, self-reported: nasal/sinus disorderUK Biobank (UKBB)Neale Lab201813963597453Brain - Putamen (basal ganglia): p = 0.01
Brain - Amygdala: p = 0.02
Brain - Caudate (basal ganglia): p = 0.02
20002_1079Non-cancer illness code, self-reported: cardiomyopathyUK Biobank (UKBB)Neale Lab20183113608303Prostate: p = 0.00591
Pituitary: p = 0.00796
Liver: p = 0.01
20002_1267Non-cancer illness code, self-reported: spinal injuryUK Biobank (UKBB)Neale Lab20185833605583Stomach: p = 0.00119
Pancreas: p = 0.01
Skin - Not Sun Exposed (Suprapubic): p = 0.02
20002_1288Non-cancer illness code, self-reported: nervous breakdownUK Biobank (UKBB)Neale Lab20185683605733Brain - Hypothalamus: p = 0.00117
Nerve - Tibial: p = 0.00534
Brain - Caudate (basal ganglia): p = 0.00784
20002_1442Non-cancer illness code, self-reported: helicobacter pyloriUK Biobank (UKBB)Neale Lab201810053601363Lung: p = 0.01
Brain - Amygdala: p = 0.02
Brain - Anterior cingulate cortex (BA24): p = 0.02
20002_1137Non-cancer illness code, self-reported: other abdominal problemUK Biobank (UKBB)Neale Lab20184223607192Skin - Not Sun Exposed (Suprapubic): p = 0.00236
Skin - Sun Exposed (Lower leg): p = 0.00236
Kidney - Cortex: p = 0.00462
20002_1327Non-cancer illness code, self-reported: low platelets/platelet disorderUK Biobank (UKBB)Neale Lab20183143608272Kidney - Cortex: p = 0.03
Uterus: p = 0.07
Esophagus - Mucosa: p = 0.08
20002_1158Non-cancer illness code, self-reported: liver failure/cirrhosisUK Biobank (UKBB)Neale Lab20182643608773Prostate: p = 0.00446
Small Intestine - Terminal Ileum: p = 0.04
Esophagus - Mucosa: p = 0.04
20002_1115Non-cancer illness code, self-reported: interstitial lung diseaseUK Biobank (UKBB)Neale Lab20181213610203Colon - Sigmoid: p = 2.32E-4
Esophagus - Muscularis: p = 0.00182
Uterus: p = 0.00308
20002_1652Non-cancer illness code, self-reported: fracture tibiaUK Biobank (UKBB)Neale Lab20184443606973Liver: p = 0.03
Adipose - Visceral (Omentum): p = 0.06
Skin - Not Sun Exposed (Suprapubic): p = 0.06
20002_1570Non-cancer illness code, self-reported: rubella / german measlesUK Biobank (UKBB)Neale Lab20184433606983Liver: p = 0.00328
Spleen: p = 0.02
Testis: p = 0.02
20002_1535Non-cancer illness code, self-reported: scoliosisUK Biobank (UKBB)Neale Lab20182473608943Artery - Aorta: p = 5.72E-4
Prostate: p = 0.00235
Artery - Coronary: p = 0.00398
20002_1250Non-cancer illness code, self-reported: bell's palsy/facial nerve palsyUK Biobank (UKBB)Neale Lab20183583607833Esophagus - Mucosa: p = 0.00639
Adrenal Gland: p = 0.02
Skin - Not Sun Exposed (Suprapubic): p = 0.02
20002_1537Non-cancer illness code, self-reported: joint painUK Biobank (UKBB)Neale Lab201812093599323Vagina: p = 0.00444
Esophagus - Mucosa: p = 0.02
Spleen: p = 0.04
20002_1279Non-cancer illness code, self-reported: eye traumaUK Biobank (UKBB)Neale Lab20185423605993Heart - Left Ventricle: p = 9.75E-5
Colon - Sigmoid: p = 0.00668
Colon - Transverse: p = 0.02
20002_1534Non-cancer illness code, self-reported: back painUK Biobank (UKBB)Neale Lab201819373592042Skin - Not Sun Exposed (Suprapubic): p = 0.00262
Skin - Sun Exposed (Lower leg): p = 0.00423
Vagina: p = 0.03
20002_1585Non-cancer illness code, self-reported: mitral regurgitation / incompetenceUK Biobank (UKBB)Neale Lab20181073610342Vagina: p = 7.62E-4
Ovary: p = 0.00983
Liver: p = 0.02
20002_1384Non-cancer illness code, self-reported: scleroderma/systemic sclerosisUK Biobank (UKBB)Neale Lab20181213610203Colon - Sigmoid: p = 0.00532
Colon - Transverse: p = 0.00532
Uterus: p = 0.02
20002_1373Non-cancer illness code, self-reported: connective tissue disorderUK Biobank (UKBB)Neale Lab20181553609863Colon - Sigmoid: p = 0.00154
Ovary: p = 0.00174
Esophagus - Gastroesophageal Junction: p = 0.02
20002_1155Non-cancer illness code, self-reported: hepatitisUK Biobank (UKBB)Neale Lab20183963607453Kidney - Cortex: p = 0.04
Spleen: p = 0.04
Brain - Anterior cingulate cortex (BA24): p = 0.04
20002_1505Non-cancer illness code, self-reported: haemorrhoids / pilesUK Biobank (UKBB)Neale Lab20189593601823Esophagus - Muscularis: p = 0.00488
Skin - Not Sun Exposed (Suprapubic): p = 0.00978
Skin - Sun Exposed (Lower leg): p = 0.00978
20002_1446Non-cancer illness code, self-reported: anaemiaUK Biobank (UKBB)Neale Lab20186023605393Thyroid: p = 0.00115
Adipose - Subcutaneous: p = 0.01
Lung: p = 0.02
20002_1196Non-cancer illness code, self-reported: urinary tract infection/kidney infectionUK Biobank (UKBB)Neale Lab201816983594433Kidney - Cortex: p = 0.01
Breast - Mammary Tissue: p = 0.02
Adrenal Gland: p = 0.09
20002_1087Non-cancer illness code, self-reported: leg claudication/ intermittent claudicationUK Biobank (UKBB)Neale Lab20182773608643Adipose - Subcutaneous: p = 0.02
Lung: p = 0.02
Kidney - Cortex: p = 0.02
20002_1510Non-cancer illness code, self-reported: dyspepsia / indigestionUK Biobank (UKBB)Neale Lab20184553606863Skin - Sun Exposed (Lower leg): p = 2.37E-4
Skin - Not Sun Exposed (Suprapubic): p = 0.00199
Brain - Cortex: p = 0.02
20002_1262Non-cancer illness code, self-reported: parkinsons diseaseUK Biobank (UKBB)Neale Lab20186523604893Colon - Sigmoid: p = 0.02
Esophagus - Gastroesophageal Junction: p = 0.03
Muscle - Skeletal: p = 0.06
20002_1633Non-cancer illness code, self-reported: fracture upper arm / humerus / elbowUK Biobank (UKBB)Neale Lab20187643603773Colon - Sigmoid: p = 0.01
Stomach: p = 0.01
Spleen: p = 0.06
20002_1656Non-cancer illness code, self-reported: fracture toeUK Biobank (UKBB)Neale Lab20182503608913Stomach: p = 0.03
Esophagus - Gastroesophageal Junction: p = 0.04
Colon - Sigmoid: p = 0.06
20002_1628Non-cancer illness code, self-reported: fracture noseUK Biobank (UKBB)Neale Lab20184943606473Ovary: p = 0.02
Whole Blood: p = 0.02
Minor Salivary Gland: p = 0.03
20002_1123Non-cancer illness code, self-reported: sleep apnoeaUK Biobank (UKBB)Neale Lab201811633599783Adipose - Visceral (Omentum): p = 0.01
Lung: p = 0.02
Ovary: p = 0.09
20002_1508Non-cancer illness code, self-reported: jaundice (unknown cause)UK Biobank (UKBB)Neale Lab20182963608453Ovary: p = 0.00156
Esophagus - Gastroesophageal Junction: p = 0.02
Esophagus - Muscularis: p = 0.02
20002_1540Non-cancer illness code, self-reported: plantar fascitisUK Biobank (UKBB)Neale Lab20181463609953Colon - Transverse: p = 0.02
Thyroid: p = 0.04
Vagina: p = 0.05
20002_1487Non-cancer illness code, self-reported: svt / supraventricular tachycardiaUK Biobank (UKBB)Neale Lab20181893609522Brain - Substantia nigra: p = 0.01
Heart - Atrial Appendage: p = 0.01
Heart - Left Ventricle: p = 0.02
20002_1532Non-cancer illness code, self-reported: disc problemUK Biobank (UKBB)Neale Lab20183293608122Adrenal Gland: p = 0.03
Adipose - Visceral (Omentum): p = 0.04
Liver: p = 0.04
20002_1567Non-cancer illness code, self-reported: infectious mononucleosis / glandular fever / epstein barr virus (ebv)UK Biobank (UKBB)Neale Lab20184643606773Brain - Anterior cingulate cortex (BA24): p = 0.01
Brain - Spinal cord (cervical c-1): p = 0.02
Brain - Cortex: p = 0.03
20002_1610Non-cancer illness code, self-reported: thyroid goitreUK Biobank (UKBB)Neale Lab20183473607943Uterus: p = 0.00806
Adipose - Subcutaneous: p = 0.02
Heart - Left Ventricle: p = 0.02
20002_1249Non-cancer illness code, self-reported: cranial nerve problem/palsyUK Biobank (UKBB)Neale Lab20182323609092Brain - Putamen (basal ganglia): p = 0.03
Pancreas: p = 0.03
Skin - Sun Exposed (Lower leg): p = 0.03
20002_1528Non-cancer illness code, self-reported: macular degenerationUK Biobank (UKBB)Neale Lab20182123609293Skin - Not Sun Exposed (Suprapubic): p = 0.00128
Skin - Sun Exposed (Lower leg): p = 0.00207
Small Intestine - Terminal Ileum: p = 0.01
20002_1200Non-cancer illness code, self-reported: ureteric obstruction/hydronephrosisUK Biobank (UKBB)Neale Lab20182533608883Ovary: p = 0.01
Colon - Transverse: p = 0.02
Skin - Sun Exposed (Lower leg): p = 0.06
20002_1648Non-cancer illness code, self-reported: fracture neck of femur / hipUK Biobank (UKBB)Neale Lab20182463608952Liver: p = 0.0021
Colon - Transverse: p = 0.005
Kidney - Cortex: p = 0.005
20002_1544Non-cancer illness code, self-reported: dupuytren's contractureUK Biobank (UKBB)Neale Lab20182653608763Breast - Mammary Tissue: p = 0.03
Esophagus - Mucosa: p = 0.03
Liver: p = 0.03
20002_1661Non-cancer illness code, self-reported: vitiligoUK Biobank (UKBB)Neale Lab20181053610363Artery - Aorta: p = 0.00766
Artery - Coronary: p = 0.00766
Pancreas: p = 0.00926
20002_1441Non-cancer illness code, self-reported: malariaUK Biobank (UKBB)Neale Lab20184283607132Kidney - Cortex: p = 0.01
Brain - Cerebellar Hemisphere: p = 0.02
Whole Blood: p = 0.02
20002_1238Non-cancer illness code, self-reported: pituitary adenoma/tumourUK Biobank (UKBB)Neale Lab20182373609043Pancreas: p = 0.00562
Heart - Atrial Appendage: p = 0.02
Heart - Left Ventricle: p = 0.02
20002_1511Non-cancer illness code, self-reported: abdominal herniaUK Biobank (UKBB)Neale Lab20182343609072Liver: p = 0.00215
Vagina: p = 0.00215
Esophagus - Mucosa: p = 0.00228
20002_1243Non-cancer illness code, self-reported: psychological/psychiatric problemUK Biobank (UKBB)Neale Lab20183633607783Brain - Substantia nigra: p = 0.02
Thyroid: p = 0.02
Small Intestine - Terminal Ileum: p = 0.03
20002_1372Non-cancer illness code, self-reported: vasculitisUK Biobank (UKBB)Neale Lab20181563609853Colon - Sigmoid: p = 5.76E-5
Colon - Transverse: p = 0.00342
Adipose - Visceral (Omentum): p = 0.01
20002_1420Non-cancer illness code, self-reported: otosclerosisUK Biobank (UKBB)Neale Lab20181893609523Artery - Aorta: p = 0.01
Lung: p = 0.04
Skin - Not Sun Exposed (Suprapubic): p = 0.05
20002_1120Non-cancer illness code, self-reported: asbestosisUK Biobank (UKBB)Neale Lab20181503609913Esophagus - Gastroesophageal Junction: p = 0.0039
Lung: p = 0.00914
Esophagus - Muscularis: p = 0.02
20002_1636Non-cancer illness code, self-reported: fracture ulnaUK Biobank (UKBB)Neale Lab20181183610232Small Intestine - Terminal Ileum: p = 0.05
Brain - Caudate (basal ganglia): p = 0.05
Brain - Frontal Cortex (BA9): p = 0.05
20002_1638Non-cancer illness code, self-reported: fracture handUK Biobank (UKBB)Neale Lab20181913609503Breast - Mammary Tissue: p = 0.00258
Testis: p = 0.02
Lung: p = 0.03
20002_1568Non-cancer illness code, self-reported: measles / morbillivirusUK Biobank (UKBB)Neale Lab201812573598843Pituitary: p = 1.53E-4
Spleen: p = 1.95E-4
Whole Blood: p = 1.95E-4
20002_1523Non-cancer illness code, self-reported: trigemminal neuralgiaUK Biobank (UKBB)Neale Lab20181573609843Esophagus - Mucosa: p = 0.00119
Stomach: p = 0.00226
Vagina: p = 0.0071
20002_1653Non-cancer illness code, self-reported: fracture fibulaUK Biobank (UKBB)Neale Lab20183773607643Liver: p = 0.03
Whole Blood: p = 0.06
Esophagus - Mucosa: p = 0.06
20002_1246Non-cancer illness code, self-reported: encephalitisUK Biobank (UKBB)Neale Lab20182383609032Liver: p = 0.02
Brain - Amygdala: p = 0.03
Muscle - Skeletal: p = 0.03
20002_1634Non-cancer illness code, self-reported: fracture forearm / wristUK Biobank (UKBB)Neale Lab20187783603633Adrenal Gland: p = 1.46E-4
Vagina: p = 0.00484
Esophagus - Mucosa: p = 0.01
20002_1501Non-cancer illness code, self-reported: pyloric stenosisUK Biobank (UKBB)Neale Lab20181053610362Esophagus - Mucosa: p = 0.01
Kidney - Cortex: p = 0.02
Artery - Tibial: p = 0.03
20002_1445Non-cancer illness code, self-reported: clotting disorder/excessive bleedingUK Biobank (UKBB)Neale Lab20183543607874Artery - Aorta: p = 0.00358
Esophagus - Gastroesophageal Junction: p = 0.00358
Esophagus - Muscularis: p = 0.00576
20002_1649Non-cancer illness code, self-reported: fracture shaft of femurUK Biobank (UKBB)Neale Lab20182113609303Skin - Sun Exposed (Lower leg): p = 5.15E-4
Skin - Not Sun Exposed (Suprapubic): p = 8.8E-4
Brain - Hypothalamus: p = 0.00392
20002_1541Non-cancer illness code, self-reported: carpal tunnel syndromeUK Biobank (UKBB)Neale Lab20186053605362Esophagus - Muscularis: p = 0.05
Vagina: p = 0.07
Esophagus - Mucosa: p = 0.12
20002_1548Non-cancer illness code, self-reported: acne/acne vulgarisUK Biobank (UKBB)Neale Lab20182093609323Adipose - Subcutaneous: p = 0.01
Whole Blood: p = 0.01
Stomach: p = 0.02
20002_1428Non-cancer illness code, self-reported: thyroiditisUK Biobank (UKBB)Neale Lab20181803609613Prostate: p = 0.01
Skin - Not Sun Exposed (Suprapubic): p = 0.02
Skin - Sun Exposed (Lower leg): p = 0.02
20002_1194Non-cancer illness code, self-reported: renal failure not requiring dialysisUK Biobank (UKBB)Neale Lab20182953608463Stomach: p = 0.00874
Artery - Aorta: p = 0.04
Nerve - Tibial: p = 0.04
20002_1512Non-cancer illness code, self-reported: umbilical herniaUK Biobank (UKBB)Neale Lab20183283608133Esophagus - Mucosa: p = 4.19E-4
Brain - Cerebellar Hemisphere: p = 0.01
Brain - Cerebellum: p = 0.01
20002_1569Non-cancer illness code, self-reported: mumps / epidemic parotitisUK Biobank (UKBB)Neale Lab20187943603473Muscle - Skeletal: p = 0.00761
Pituitary: p = 0.02
Prostate: p = 0.02
20002_1514Non-cancer illness code, self-reported: cystitisUK Biobank (UKBB)Neale Lab20182993608423Artery - Aorta: p = 0.02
Brain - Cerebellum: p = 0.04
Artery - Coronary: p = 0.07
20002_1308Non-cancer illness code, self-reported: osteomyelitisUK Biobank (UKBB)Neale Lab20185643605773Pancreas: p = 0.02
Heart - Atrial Appendage: p = 0.03
Whole Blood: p = 0.03
20002_1433Non-cancer illness code, self-reported: cerebral palsyUK Biobank (UKBB)Neale Lab20181233610182Skin - Sun Exposed (Lower leg): p = 0.02
Brain - Cerebellar Hemisphere: p = 0.04
Brain - Cerebellum: p = 0.04
20002_1627Non-cancer illness code, self-reported: fracture jawUK Biobank (UKBB)Neale Lab20181653609763Spleen: p = 0.01
Colon - Sigmoid: p = 0.03
Heart - Left Ventricle: p = 0.03
20002_1562Non-cancer illness code, self-reported: food intoleranceUK Biobank (UKBB)Neale Lab20181543609873Muscle - Skeletal: p = 0.00164
Stomach: p = 0.00843
Heart - Atrial Appendage: p = 0.00901
20002_1529Non-cancer illness code, self-reported: dry eyesUK Biobank (UKBB)Neale Lab20185153606263Muscle - Skeletal: p = 0.00502
Pancreas: p = 0.01
Colon - Sigmoid: p = 0.05
20002_1635Non-cancer illness code, self-reported: fracture radiusUK Biobank (UKBB)Neale Lab20181653609763Thyroid: p = 5.33E-4
Nerve - Tibial: p = 0.00651
Minor Salivary Gland: p = 0.02
20002_1076Non-cancer illness code, self-reported: heart failure/pulmonary odemaUK Biobank (UKBB)Neale Lab20182473608943Brain - Substantia nigra: p = 0.00156
Prostate: p = 0.02
Brain - Amygdala: p = 0.04
20002_1683Non-cancer illness code, self-reported: benign neuromaUK Biobank (UKBB)Neale Lab20181203610213Artery - Aorta: p = 0.02
Lung: p = 0.02
Stomach: p = 0.03
20002_1435Non-cancer illness code, self-reported: optic neuritisUK Biobank (UKBB)Neale Lab20181293610123Vagina: p = 0.03
Small Intestine - Terminal Ileum: p = 0.08
Adipose - Subcutaneous: p = 0.08
20002_1632Non-cancer illness code, self-reported: fracture shoulder / scapulaUK Biobank (UKBB)Neale Lab20182053609363Heart - Atrial Appendage: p = 0.00321
Brain - Frontal Cortex (BA9): p = 0.00436
Brain - Anterior cingulate cortex (BA24): p = 0.00674
20002_1229Non-cancer illness code, self-reported: parathyroid gland problem (not cancer)UK Biobank (UKBB)Neale Lab20181253610163Liver: p = 0.0013
Brain - Hippocampus: p = 0.00502
Brain - Substantia nigra: p = 0.01
20002_1454Non-cancer illness code, self-reported: blistering/desquamating skin disorderUK Biobank (UKBB)Neale Lab20185793605623Adrenal Gland: p = 0.04
Esophagus - Gastroesophageal Junction: p = 0.04
Esophagus - Muscularis: p = 0.06
20002_1573Non-cancer illness code, self-reported: shinglesUK Biobank (UKBB)Neale Lab20183273608143Artery - Coronary: p = 0.0016
Artery - Tibial: p = 0.00261
Lung: p = 0.00396
20002_1654Non-cancer illness code, self-reported: fracture footUK Biobank (UKBB)Neale Lab20182403609013Testis: p = 0.00559
Liver: p = 0.01
Esophagus - Muscularis: p = 0.03
20002_1597Non-cancer illness code, self-reported: tinnitus / tiniitisUK Biobank (UKBB)Neale Lab20186203605213Lung: p = 0.00522
Liver: p = 0.01
Skin - Sun Exposed (Lower leg): p = 0.03
20002_1437Non-cancer illness code, self-reported: myasthenia gravisUK Biobank (UKBB)Neale Lab20181053610362Skin - Sun Exposed (Lower leg): p = 0.00337
Nerve - Tibial: p = 0.00443
Skin - Not Sun Exposed (Suprapubic): p = 0.00533
20002_1495Non-cancer illness code, self-reported: lymphoedemaUK Biobank (UKBB)Neale Lab20181803609612Lung: p = 0.00306
Nerve - Tibial: p = 0.02
Esophagus - Gastroesophageal Junction: p = 0.04
20002_1631Non-cancer illness code, self-reported: fracture clavicle / collar boneUK Biobank (UKBB)Neale Lab20184093607323Liver: p = 0.00766
Brain - Frontal Cortex (BA9): p = 0.02
Thyroid: p = 0.02
20002_1469Non-cancer illness code, self-reported: post-traumatic stress disorderUK Biobank (UKBB)Neale Lab20182663608752Nerve - Tibial: p = 0.00281
Skin - Not Sun Exposed (Suprapubic): p = 0.03
Esophagus - Muscularis: p = 0.04
20002_1491Non-cancer illness code, self-reported: brain haemorrhageUK Biobank (UKBB)Neale Lab20181103610313Brain - Substantia nigra: p = 0.03
Skin - Sun Exposed (Lower leg): p = 0.05
Thyroid: p = 0.05
20002_1536Non-cancer illness code, self-reported: spinal stenosisUK Biobank (UKBB)Neale Lab20181103610313Breast - Mammary Tissue: p = 0.00502
Adipose - Subcutaneous: p = 0.00696
Adipose - Visceral (Omentum): p = 0.00696
20002_1254Non-cancer illness code, self-reported: peripheral nerve disorderUK Biobank (UKBB)Neale Lab20182063609353Adipose - Visceral (Omentum): p = 7.58E-5
Breast - Mammary Tissue: p = 6.71E-4
Lung: p = 0.00462
20002_1322Non-cancer illness code, self-reported: myositis/myopathyUK Biobank (UKBB)Neale Lab20181453609963Esophagus - Mucosa: p = 0.04
Thyroid: p = 0.05
Small Intestine - Terminal Ileum: p = 0.07
20002_1240Non-cancer illness code, self-reported: neurological injury/traumaUK Biobank (UKBB)Neale Lab20181043610373Adipose - Visceral (Omentum): p = 0.01
Breast - Mammary Tissue: p = 0.01
Brain - Hippocampus: p = 0.01
20002_1497Non-cancer illness code, self-reported: pneumothoraxUK Biobank (UKBB)Neale Lab20181573609843Skin - Not Sun Exposed (Suprapubic): p = 1.27E-4
Skin - Sun Exposed (Lower leg): p = 6.59E-4
Adipose - Visceral (Omentum): p = 0.00458
20002_1578Non-cancer illness code, self-reported: hepatitis aUK Biobank (UKBB)Neale Lab20181383610032Esophagus - Gastroesophageal Junction: p = 0.00472
Esophagus - Muscularis: p = 0.00472
Heart - Atrial Appendage: p = 0.03
20002_1414Non-cancer illness code, self-reported: throat or larynx disorderUK Biobank (UKBB)Neale Lab20183253608163Vagina: p = 0.00164
Brain - Anterior cingulate cortex (BA24): p = 0.00435
Brain - Frontal Cortex (BA9): p = 0.00435
20002_1394Non-cancer illness code, self-reported: peripheral nerve injuryUK Biobank (UKBB)Neale Lab20182273609143Skin - Not Sun Exposed (Suprapubic): p = 0.00566
Pancreas: p = 0.04
Vagina: p = 0.04
20002_1499Non-cancer illness code, self-reported: labyrinthitisUK Biobank (UKBB)Neale Lab20181883609532Minor Salivary Gland: p = 0.11
Esophagus - Muscularis: p = 0.16
Lung: p = 0.16
20002_1425Non-cancer illness code, self-reported: cerebral aneurysmUK Biobank (UKBB)Neale Lab20182563608853Brain - Cerebellum: p = 0.00862
Pituitary: p = 0.02
Colon - Sigmoid: p = 0.02
20002_1616Non-cancer illness code, self-reported: insomniaUK Biobank (UKBB)Neale Lab20183553607862Brain - Putamen (basal ganglia): p = 0.00489
Colon - Sigmoid: p = 0.0075
Brain - Caudate (basal ganglia): p = 0.01
20002_1080Non-cancer illness code, self-reported: pericardial problemUK Biobank (UKBB)Neale Lab20182023609393Adipose - Subcutaneous: p = 0.00243
Lung: p = 0.00243
Breast - Mammary Tissue: p = 0.03
20002_1549Non-cancer illness code, self-reported: lichen planusUK Biobank (UKBB)Neale Lab20181553609863Spleen: p = 0.00446
Brain - Nucleus accumbens (basal ganglia): p = 0.00691
Brain - Caudate (basal ganglia): p = 0.02
20002_1613Non-cancer illness code, self-reported: blepharitis / eyelid infectionUK Biobank (UKBB)Neale Lab20181233610183Pancreas: p = 0.00626
Whole Blood: p = 0.00822
Adipose - Subcutaneous: p = 0.02
20002_1650Non-cancer illness code, self-reported: fracture patella / kneeUK Biobank (UKBB)Neale Lab20182353609063Brain - Anterior cingulate cortex (BA24): p = 0.03
Brain - Frontal Cortex (BA9): p = 0.03
Brain - Spinal cord (cervical c-1): p = 0.03
20002_1256Non-cancer illness code, self-reported: acute infective polyneuritis/guillain-barre syndromeUK Biobank (UKBB)Neale Lab20181703609712Lung: p = 0.03
Pancreas: p = 0.03
Ovary: p = 0.05
20002_1083Non-cancer illness code, self-reported: subdural haemorrhage/haematomaUK Biobank (UKBB)Neale Lab20181543609873Breast - Mammary Tissue: p = 0.00285
Adipose - Visceral (Omentum): p = 0.00708
Brain - Frontal Cortex (BA9): p = 0.00968
20002_1161Non-cancer illness code, self-reported: gall bladder diseaseUK Biobank (UKBB)Neale Lab20182023609392Small Intestine - Terminal Ileum: p = 0.02
Ovary: p = 0.02
Skin - Sun Exposed (Lower leg): p = 0.02
20002_1191Non-cancer illness code, self-reported: gastrointestinal bleedingUK Biobank (UKBB)Neale Lab20181423609993Adrenal Gland: p = 0.00255
Colon - Transverse: p = 0.00743
Stomach: p = 0.01
20002_1603Non-cancer illness code, self-reported: rectal prolapseUK Biobank (UKBB)Neale Lab20181383610033Brain - Caudate (basal ganglia): p = 0.02
Adipose - Subcutaneous: p = 0.04
Muscle - Skeletal: p = 0.04
20002_1234Non-cancer illness code, self-reported: adrenocortical insufficiency/addison's diseaseUK Biobank (UKBB)Neale Lab20181583609835Lung: p = 3.69E-6
Spleen: p = 3.69E-6
Whole Blood: p = 7.42E-4
20002_1438Non-cancer illness code, self-reported: polycythaemia veraUK Biobank (UKBB)Neale Lab20181593609823Esophagus - Mucosa: p = 5.62E-4
Vagina: p = 0.00324
Muscle - Skeletal: p = 0.00709
20002_1605Non-cancer illness code, self-reported: femoral herniaUK Biobank (UKBB)Neale Lab20181023610393Liver: p = 0.00914
Stomach: p = 0.00984
Artery - Coronary: p = 0.05
20002_1509Non-cancer illness code, self-reported: gastroenteritis/dysentryUK Biobank (UKBB)Neale Lab20181043610373Adipose - Subcutaneous: p = 0.00445
Nerve - Tibial: p = 0.00445
Liver: p = 0.00707
20002_1602Non-cancer illness code, self-reported: bowel / intestinal obstructionUK Biobank (UKBB)Neale Lab20181533609883Heart - Atrial Appendage: p = 0.04
Testis: p = 0.04
Brain - Cerebellar Hemisphere: p = 0.07
20002_1550Non-cancer illness code, self-reported: lichen sclerosisUK Biobank (UKBB)Neale Lab20181233610183Colon - Transverse: p = 0.01
Brain - Substantia nigra: p = 0.03
Brain - Anterior cingulate cortex (BA24): p = 0.03
20002_1276Non-cancer illness code, self-reported: diabetic eye diseaseUK Biobank (UKBB)Neale Lab20186993604423Lung: p = 2.79E-4
Uterus: p = 2.79E-4
Whole Blood: p = 0.02
20002_1427Non-cancer illness code, self-reported: polycystic kidneyUK Biobank (UKBB)Neale Lab20182513608902Liver: p = 0.00932
Esophagus - Muscularis: p = 0.06
Kidney - Cortex: p = 0.06
20002_1575Non-cancer illness code, self-reported: herpes simplexUK Biobank (UKBB)Neale Lab20181543609873Brain - Putamen (basal ganglia): p = 0.00626
Brain - Amygdala: p = 0.01
Brain - Caudate (basal ganglia): p = 0.01
20002_1419Non-cancer illness code, self-reported: vocal cord polypUK Biobank (UKBB)Neale Lab20181543609873Esophagus - Gastroesophageal Junction: p = 0.01
Skin - Sun Exposed (Lower leg): p = 0.03
Vagina: p = 0.03
20002_1525Non-cancer illness code, self-reported: benign / essential tremorUK Biobank (UKBB)Neale Lab20181103610313Prostate: p = 0.00312
Brain - Caudate (basal ganglia): p = 0.02
Brain - Cerebellar Hemisphere: p = 0.02
20002_1647Non-cancer illness code, self-reported: fracture pelvisUK Biobank (UKBB)Neale Lab20181513609903Esophagus - Mucosa: p = 0.00874
Colon - Transverse: p = 0.02
Whole Blood: p = 0.02
20002_1192Non-cancer illness code, self-reported: renal/kidney failureUK Biobank (UKBB)Neale Lab20181713609702Stomach: p = 0.03
Pancreas: p = 0.04
Skin - Not Sun Exposed (Suprapubic): p = 0.04
20002_1290Non-cancer illness code, self-reported: deliberate self-harm/suicide attemptUK Biobank (UKBB)Neale Lab20181873609543Artery - Coronary: p = 0.00282
Artery - Tibial: p = 0.00456
Uterus: p = 0.00952
20002_1655Non-cancer illness code, self-reported: fracture metatarsalUK Biobank (UKBB)Neale Lab20181393610023Brain - Substantia nigra: p = 0.01
Brain - Hypothalamus: p = 0.02
Brain - Nucleus accumbens (basal ganglia): p = 0.04
20002_1193Non-cancer illness code, self-reported: renal failure requiring dialysisUK Biobank (UKBB)Neale Lab20181813609603Skin - Not Sun Exposed (Suprapubic): p = 9.07E-11
Skin - Sun Exposed (Lower leg): p = 9.07E-11
Esophagus - Mucosa: p = 4.8E-5
20002_1468Non-cancer illness code, self-reported: diabetic neuropathy/ulcersUK Biobank (UKBB)Neale Lab20181233610183Lung: p = 4.33E-4
Esophagus - Mucosa: p = 0.02
Prostate: p = 0.02
20003_1140868226Treatment/medication code: aspirinUK Biobank (UKBB)Neale Lab2018480813130605Spleen: p = 9.33E-4
Artery - Tibial: p = 0.00379
Adrenal Gland: p = 0.00745
20003_1140879802Treatment/medication code: amlodipineUK Biobank (UKBB)Neale Lab2018145883465535Skin - Sun Exposed (Lower leg): p = 1.42E-4
Vagina: p = 0.00169
Heart - Atrial Appendage: p = 0.00456
20003_1140852948Treatment/medication code: calcium+vitamin d 500units tabletUK Biobank (UKBB)Neale Lab201815783595633Ovary: p = 0.00199
Skin - Sun Exposed (Lower leg): p = 0.01
Skin - Not Sun Exposed (Suprapubic): p = 0.02
20003_2038460150Treatment/medication code: paracetamolUK Biobank (UKBB)Neale Lab2018663472947944Lung: p = 9.37E-4
Uterus: p = 0.00133
Brain - Putamen (basal ganglia): p = 0.00337
20003_1140909786Treatment/medication code: beclometasoneUK Biobank (UKBB)Neale Lab201832993578423Lung: p = 3.26E-4
Esophagus - Mucosa: p = 0.00911
Small Intestine - Terminal Ileum: p = 0.03
20003_1140870788Treatment/medication code: calcium saltsUK Biobank (UKBB)Neale Lab201822083589333Muscle - Skeletal: p = 0.00115
Adrenal Gland: p = 0.00658
Heart - Left Ventricle: p = 0.01
20003_1140923346Treatment/medication code: co-codamolUK Biobank (UKBB)Neale Lab201883843527574Muscle - Skeletal: p = 9.13E-4
Prostate: p = 0.00708
Adipose - Visceral (Omentum): p = 0.00735
20003_1140874852Treatment/medication code: thyroxine sodiumUK Biobank (UKBB)Neale Lab201810123601293Lung: p = 3.25E-4
Artery - Coronary: p = 0.00284
Artery - Aorta: p = 0.00691
20003_1140921828Treatment/medication code: dicloflex 25mg e/c tabletUK Biobank (UKBB)Neale Lab20184303607112Brain - Spinal cord (cervical c-1): p = 0.02
Nerve - Tibial: p = 0.02
Brain - Nucleus accumbens (basal ganglia): p = 0.05
20003_1140861958Treatment/medication code: simvastatinUK Biobank (UKBB)Neale Lab2018409213202204Liver: p = 6.48E-10
Spleen: p = 0.00275
Lung: p = 0.00294
20003_1141145668Treatment/medication code: diovan 40mg capsuleUK Biobank (UKBB)Neale Lab20183613607803Spleen: p = 0.00339
Vagina: p = 0.00792
Prostate: p = 0.01
20003_1140888552Treatment/medication code: enalaprilUK Biobank (UKBB)Neale Lab201828033583383Whole Blood: p = 0.00125
Esophagus - Gastroesophageal Junction: p = 0.01
Liver: p = 0.01
20003_99999Treatment/medication code: Free-text entry, unable to be codedUK Biobank (UKBB)Neale Lab2018122493488923Vagina: p = 0.00549
Small Intestine - Terminal Ileum: p = 0.01
Esophagus - Mucosa: p = 0.02
20003_1141194794Treatment/medication code: bendroflumethiazideUK Biobank (UKBB)Neale Lab2018201963409454Uterus: p = 2.13E-4
Heart - Atrial Appendage: p = 6.04E-4
Prostate: p = 0.00421
20003_1140874744Treatment/medication code: gliclazideUK Biobank (UKBB)Neale Lab201830073581343Artery - Aorta: p = 5.6E-5
Uterus: p = 9.27E-5
Adipose - Subcutaneous: p = 3.46E-4
20003_1140861090Treatment/medication code: adalat 5mg capsuleUK Biobank (UKBB)Neale Lab20188403603012Heart - Left Ventricle: p = 0.00196
Heart - Atrial Appendage: p = 0.00511
Breast - Mammary Tissue: p = 0.04
20003_1140880072Treatment/medication code: gamolenic acidUK Biobank (UKBB)Neale Lab20181113610303Brain - Cerebellum: p = 0.03
Brain - Putamen (basal ganglia): p = 0.03
Brain - Caudate (basal ganglia): p = 0.06
20003_1140862628Treatment/medication code: piriton 4mg tabletUK Biobank (UKBB)Neale Lab20185683605733Skin - Not Sun Exposed (Suprapubic): p = 0.01
Skin - Sun Exposed (Lower leg): p = 0.02
Artery - Coronary: p = 0.05
20003_1140871310Treatment/medication code: ibuprofenUK Biobank (UKBB)Neale Lab2018450053161364Brain - Putamen (basal ganglia): p = 0.00338
Brain - Amygdala: p = 0.00614
Brain - Anterior cingulate cortex (BA24): p = 0.00614
20003_1140909806Treatment/medication code: dosulepinUK Biobank (UKBB)Neale Lab201812863598553Brain - Anterior cingulate cortex (BA24): p = 6.37E-4
Brain - Hippocampus: p = 6.37E-4
Brain - Amygdala: p = 0.00833
20003_1187Treatment/medication code: chondroitin productUK Biobank (UKBB)Neale Lab201846633564783Pancreas: p = 5.72E-4
Esophagus - Mucosa: p = 0.01
Muscle - Skeletal: p = 0.03
20003_1141164828Treatment/medication code: adcal-d3 1.5g/10micrograms chewable tabletUK Biobank (UKBB)Neale Lab201824353587062Small Intestine - Terminal Ileum: p = 0.03
Liver: p = 0.03
Adipose - Subcutaneous: p = 0.06
20003_1140884488Treatment/medication code: diclofenacUK Biobank (UKBB)Neale Lab201875453535963Artery - Coronary: p = 0.01
Brain - Anterior cingulate cortex (BA24): p = 0.01
Brain - Caudate (basal ganglia): p = 0.02
20003_1140870856Treatment/medication code: calcichew 1.25g chewable tabletUK Biobank (UKBB)Neale Lab20187723603693Pancreas: p = 0.02
Uterus: p = 0.02
Stomach: p = 0.06
20003_1193Treatment/medication code: omega-3/fish oil supplementUK Biobank (UKBB)Neale Lab2018136893474523Artery - Tibial: p = 0.00707
Uterus: p = 0.03
Muscle - Skeletal: p = 0.03
20003_1141174520Treatment/medication code: symbicort 100/6 turbohalerUK Biobank (UKBB)Neale Lab201822493588923Whole Blood: p = 0.00115
Lung: p = 0.00209
Spleen: p = 0.00209
20003_1140865396Treatment/medication code: buscopan 10mg tabletUK Biobank (UKBB)Neale Lab20183383608033Skin - Not Sun Exposed (Suprapubic): p = 0.00843
Adipose - Visceral (Omentum): p = 0.03
Uterus: p = 0.03
20003_1140909674Treatment/medication code: cod liver oil capsuleUK Biobank (UKBB)Neale Lab2018210343401073Heart - Atrial Appendage: p = 0.01
Thyroid: p = 0.04
Nerve - Tibial: p = 0.07
20003_1140921600Treatment/medication code: citalopramUK Biobank (UKBB)Neale Lab201861853549563Spleen: p = 8.04E-4
Nerve - Tibial: p = 0.00548
Adipose - Subcutaneous: p = 0.01
20003_1140884600Treatment/medication code: metforminUK Biobank (UKBB)Neale Lab201889683521735Uterus: p = 9.89E-4
Heart - Atrial Appendage: p = 0.00141
Heart - Left Ventricle: p = 0.00141
20003_1140875408Treatment/medication code: allopurinolUK Biobank (UKBB)Neale Lab201841083570335Kidney - Cortex: p = 7.78E-5
Liver: p = 3.41E-4
Skin - Sun Exposed (Lower leg): p = 0.00421
20003_1140871050Treatment/medication code: calcichew d3 tabletUK Biobank (UKBB)Neale Lab201834233577183Spleen: p = 1.55E-4
Whole Blood: p = 0.00506
Lung: p = 0.00915
20003_1141146234Treatment/medication code: atorvastatinUK Biobank (UKBB)Neale Lab2018108053503365Liver: p = 1.34E-7
Adipose - Subcutaneous: p = 0.00102
Spleen: p = 0.00312
20003_1140909702Treatment/medication code: sulfasalazineUK Biobank (UKBB)Neale Lab20187103604315Spleen: p = 5.68E-6
Lung: p = 1.13E-5
Whole Blood: p = 5.65E-5
20003_1140916356Treatment/medication code: losartanUK Biobank (UKBB)Neale Lab201832683578733Muscle - Skeletal: p = 5.6E-4
Lung: p = 0.00342
Spleen: p = 0.00721
20003_1140866738Treatment/medication code: atenololUK Biobank (UKBB)Neale Lab2018139513471904Kidney - Cortex: p = 1.21E-4
Small Intestine - Terminal Ileum: p = 0.00317
Adrenal Gland: p = 0.00421
20003_1140922174Treatment/medication code: alendronate sodiumUK Biobank (UKBB)Neale Lab201841033570384Whole Blood: p = 0.00113
Lung: p = 0.00175
Artery - Coronary: p = 0.00594
20003_2038459704Treatment/medication code: carbamazepineUK Biobank (UKBB)Neale Lab20185513605903Lung: p = 0.01
Esophagus - Gastroesophageal Junction: p = 0.02
Brain - Caudate (basal ganglia): p = 0.02
20003_1140867878Treatment/medication code: sertralineUK Biobank (UKBB)Neale Lab201815313596103Brain - Hypothalamus: p = 0.02
Stomach: p = 0.04
Brain - Nucleus accumbens (basal ganglia): p = 0.06
20003_1140917428Treatment/medication code: angitil sr 90 m/r capsuleUK Biobank (UKBB)Neale Lab20181253610162Thyroid: p = 0.00581
Minor Salivary Gland: p = 0.01
Esophagus - Muscularis: p = 0.02
20003_1140881702Treatment/medication code: adalate 10mg capsuleUK Biobank (UKBB)Neale Lab20182743608673Adrenal Gland: p = 0.00824
Kidney - Cortex: p = 0.03
Ovary: p = 0.03
20003_1140882694Treatment/medication code: betnovate creamUK Biobank (UKBB)Neale Lab201812663598753Kidney - Cortex: p = 0.00843
Whole Blood: p = 0.02
Esophagus - Mucosa: p = 0.04
20003_1141188442Treatment/medication code: glucosamine productUK Biobank (UKBB)Neale Lab2018242133369283Esophagus - Mucosa: p = 0.01
Vagina: p = 0.01
Heart - Atrial Appendage: p = 0.02
20003_1141191044Treatment/medication code: levothyroxine sodiumUK Biobank (UKBB)Neale Lab2018146893464524Spleen: p = 1.43E-11
Whole Blood: p = 1.5E-10
Small Intestine - Terminal Ileum: p = 8.51E-6
20003_1140864752Treatment/medication code: lansoprazoleUK Biobank (UKBB)Neale Lab2018128323483093Artery - Aorta: p = 0.02
Kidney - Cortex: p = 0.02
Skin - Not Sun Exposed (Suprapubic): p = 0.02
20003_1140860696Treatment/medication code: lisinoprilUK Biobank (UKBB)Neale Lab201899713511704Muscle - Skeletal: p = 2.81E-4
Spleen: p = 0.00647
Heart - Atrial Appendage: p = 0.02
20003_1140923350Treatment/medication code: co-dydramolUK Biobank (UKBB)Neale Lab201822603588813Uterus: p = 0.00262
Esophagus - Gastroesophageal Junction: p = 0.00591
Heart - Atrial Appendage: p = 0.02
20003_1140865580Treatment/medication code: asacol 400mg e/c tabletUK Biobank (UKBB)Neale Lab20184863606553Lung: p = 5.37E-4
Colon - Transverse: p = 8.56E-4
Nerve - Tibial: p = 0.00112
20003_1141172918Treatment/medication code: celluvisc 1% single-use eye dropsUK Biobank (UKBB)Neale Lab20182733608683Thyroid: p = 0.01
Adipose - Subcutaneous: p = 0.02
Esophagus - Gastroesophageal Junction: p = 0.02
20003_1140879616Treatment/medication code: amitriptylineUK Biobank (UKBB)Neale Lab201868243543173Minor Salivary Gland: p = 0.02
Brain - Cerebellum: p = 0.02
Lung: p = 0.02
20003_1140863152Treatment/medication code: diazepamUK Biobank (UKBB)Neale Lab20189873601542Pancreas: p = 0.01
Brain - Caudate (basal ganglia): p = 0.04
Ovary: p = 0.04
20003_1140872198Treatment/medication code: sodium valproateUK Biobank (UKBB)Neale Lab20183503607913Colon - Transverse: p = 0.00795
Colon - Sigmoid: p = 0.02
Lung: p = 0.02
20003_1141167594Treatment/medication code: qvar 50 inhalerUK Biobank (UKBB)Neale Lab201813623597793Pancreas: p = 2.65E-4
Minor Salivary Gland: p = 7.85E-4
Esophagus - Mucosa: p = 0.00192
20003_1141146428Treatment/medication code: fexofenadineUK Biobank (UKBB)Neale Lab201811453599963Spleen: p = 1.1E-4
Prostate: p = 0.00732
Brain - Caudate (basal ganglia): p = 0.01
20003_1141156836Treatment/medication code: candesartan cilexetilUK Biobank (UKBB)Neale Lab201838753572663Muscle - Skeletal: p = 3.26E-4
Heart - Atrial Appendage: p = 0.00599
Colon - Sigmoid: p = 0.01
20003_1141180036Treatment/medication code: fybogel orange s/f granulesUK Biobank (UKBB)Neale Lab20187353604063Kidney - Cortex: p = 8.17E-4
Liver: p = 0.00696
Colon - Transverse: p = 0.00796
20003_1140888386Treatment/medication code: iron productUK Biobank (UKBB)Neale Lab201810093601323Artery - Coronary: p = 0.00543
Liver: p = 0.03
Esophagus - Gastroesophageal Junction: p = 0.04
20003_1140862382Treatment/medication code: becotide 50 inhalerUK Biobank (UKBB)Neale Lab201822063589354Lung: p = 4.34E-4
Uterus: p = 5.11E-4
Kidney - Cortex: p = 0.00199
20003_1141151288Treatment/medication code: naramig 2.5mg tabletUK Biobank (UKBB)Neale Lab20182633608782Stomach: p = 0.02
Whole Blood: p = 0.02
Vagina: p = 0.02
20003_1140884654Treatment/medication code: beclomethasoneUK Biobank (UKBB)Neale Lab201814403597013Breast - Mammary Tissue: p = 0.00329
Lung: p = 0.01
Whole Blood: p = 0.02
20003_1141167334Treatment/medication code: colofac-100 tabletUK Biobank (UKBB)Neale Lab20184623606793Liver: p = 0.00696
Esophagus - Gastroesophageal Junction: p = 0.02
Whole Blood: p = 0.03
20003_1140861806Treatment/medication code: aspirin 75mg tabletUK Biobank (UKBB)Neale Lab201821733589682Esophagus - Mucosa: p = 0.01
Vagina: p = 0.03
Artery - Aorta: p = 0.04
20003_1140916682Treatment/medication code: evening primrose oilUK Biobank (UKBB)Neale Lab201857303554113Muscle - Skeletal: p = 0.01
Adipose - Subcutaneous: p = 0.03
Lung: p = 0.07
20003_1140876592Treatment/medication code: multivitamin+mineral preparationsUK Biobank (UKBB)Neale Lab201849973561443Stomach: p = 0.03
Skin - Sun Exposed (Lower leg): p = 0.04
Brain - Cerebellum: p = 0.06
20003_1140874790Treatment/medication code: betamethasoneUK Biobank (UKBB)Neale Lab20185633605782Liver: p = 0.00727
Vagina: p = 0.07
Adrenal Gland: p = 0.08
20003_1140884516Treatment/medication code: thyroxine productUK Biobank (UKBB)Neale Lab201842463568955Spleen: p = 3.13E-7
Whole Blood: p = 4.52E-7
Lung: p = 5.13E-6
20003_1141162824Treatment/medication code: detrusitol 1mg tabletUK Biobank (UKBB)Neale Lab20185513605903Small Intestine - Terminal Ileum: p = 0.00468
Vagina: p = 0.02
Lung: p = 0.02
20003_1140879540Treatment/medication code: fluoxetineUK Biobank (UKBB)Neale Lab201841403570013Nerve - Tibial: p = 0.01
Adrenal Gland: p = 0.04
Lung: p = 0.04
20003_1140869930Treatment/medication code: azathioprineUK Biobank (UKBB)Neale Lab20187723603693Skin - Sun Exposed (Lower leg): p = 3.59E-6
Skin - Not Sun Exposed (Suprapubic): p = 1.17E-5
Colon - Sigmoid: p = 0.02
20003_1140909726Treatment/medication code: vitamin c productUK Biobank (UKBB)Neale Lab201845473565942Adipose - Visceral (Omentum): p = 0.05
Pancreas: p = 0.05
Artery - Coronary: p = 0.07
20003_1140870390Treatment/medication code: ferrous sulphateUK Biobank (UKBB)Neale Lab201817603593815Lung: p = 2.37E-5
Spleen: p = 0.0022
Pancreas: p = 0.0051
20003_1140879778Treatment/medication code: doxazosinUK Biobank (UKBB)Neale Lab201840433570984Colon - Sigmoid: p = 0.00201
Lung: p = 0.00201
Muscle - Skeletal: p = 0.00396
20003_1140878226Treatment/medication code: diprobase creamUK Biobank (UKBB)Neale Lab20185863605552Vagina: p = 0.00637
Skin - Sun Exposed (Lower leg): p = 0.01
Whole Blood: p = 0.03
20003_1140879424Treatment/medication code: alverineUK Biobank (UKBB)Neale Lab20182233609183Artery - Aorta: p = 2.76E-6
Artery - Coronary: p = 2.76E-6
Uterus: p = 3.31E-5
20003_1140910494Treatment/medication code: b12 - hydroxocobalamin prepUK Biobank (UKBB)Neale Lab20182913608503Colon - Sigmoid: p = 0.00113
Ovary: p = 0.00236
Esophagus - Gastroesophageal Junction: p = 0.00454
20003_1140872150Treatment/medication code: clonazepamUK Biobank (UKBB)Neale Lab20182593608823Kidney - Cortex: p = 0.03
Lung: p = 0.03
Prostate: p = 0.04
20003_1140861924Treatment/medication code: bezafibrateUK Biobank (UKBB)Neale Lab20183383608033Liver: p = 0.00321
Brain - Hippocampus: p = 0.01
Brain - Putamen (basal ganglia): p = 0.01
20003_1140862168Treatment/medication code: bricanyl 250mcg inhalerUK Biobank (UKBB)Neale Lab20188223603193Whole Blood: p = 8.22E-5
Skin - Sun Exposed (Lower leg): p = 0.02
Skin - Not Sun Exposed (Suprapubic): p = 0.04
20003_1140860806Treatment/medication code: ramiprilUK Biobank (UKBB)Neale Lab2018168693442725Uterus: p = 5.86E-4
Spleen: p = 0.00125
Prostate: p = 0.00377
20003_1141176832Treatment/medication code: seretide 50 evohalerUK Biobank (UKBB)Neale Lab201842693568725Lung: p = 3.46E-10
Spleen: p = 1.23E-6
Whole Blood: p = 1.94E-5
20003_1203Treatment/medication code: aloe vera productUK Biobank (UKBB)Neale Lab20183623607793Muscle - Skeletal: p = 0.00173
Liver: p = 0.02
Artery - Tibial: p = 0.03
20003_1140867726Treatment/medication code: lofepramineUK Biobank (UKBB)Neale Lab20182823608593Pancreas: p = 0.03
Muscle - Skeletal: p = 0.04
Small Intestine - Terminal Ileum: p = 0.06
20003_1140865634Treatment/medication code: omeprazoleUK Biobank (UKBB)Neale Lab2018211193400224Lung: p = 0.00115
Kidney - Cortex: p = 0.00151
Nerve - Tibial: p = 0.00668
20003_1140888646Treatment/medication code: felodipineUK Biobank (UKBB)Neale Lab201830903580513Stomach: p = 0.04
Lung: p = 0.08
Whole Blood: p = 0.08
20003_1140879406Treatment/medication code: ranitidineUK Biobank (UKBB)Neale Lab201859353552063Adipose - Subcutaneous: p = 0.02
Adipose - Visceral (Omentum): p = 0.05
Artery - Aorta: p = 0.05
20003_1189Treatment/medication code: co-enzyme q10/ubiquinone/bio-quinone/coenzyme q10UK Biobank (UKBB)Neale Lab201812263599153Muscle - Skeletal: p = 0.00308
Artery - Aorta: p = 0.00502
Stomach: p = 0.01
20003_1140910640Treatment/medication code: luteineUK Biobank (UKBB)Neale Lab20182783608633Esophagus - Mucosa: p = 0.00527
Skin - Sun Exposed (Lower leg): p = 0.01
Skin - Not Sun Exposed (Suprapubic): p = 0.03
20003_1141153026Treatment/medication code: lercanidipineUK Biobank (UKBB)Neale Lab20188733602683Prostate: p = 4.93E-4
Artery - Tibial: p = 0.03
Thyroid: p = 0.03
20003_1140888688Treatment/medication code: betahistineUK Biobank (UKBB)Neale Lab201810673600743Colon - Sigmoid: p = 0.00308
Prostate: p = 0.02
Ovary: p = 0.03
20003_1140862236Treatment/medication code: atrovent 20micrograms inhalerUK Biobank (UKBB)Neale Lab20183623607792Brain - Cerebellum: p = 0.02
Thyroid: p = 0.03
Brain - Cerebellar Hemisphere: p = 0.04
20003_1140861998Treatment/medication code: ventolin 100micrograms inhalerUK Biobank (UKBB)Neale Lab2018103803507615Whole Blood: p = 4.06E-8
Spleen: p = 3.39E-6
Lung: p = 1.18E-5
20003_1140862574Treatment/medication code: pulmicort ls 50micrograms inhalerUK Biobank (UKBB)Neale Lab20185513605903Esophagus - Gastroesophageal Junction: p = 0.00175
Esophagus - Muscularis: p = 0.00952
Minor Salivary Gland: p = 0.02
20003_1140864286Treatment/medication code: flixotide 25micrograms inhalerUK Biobank (UKBB)Neale Lab20186073605343Spleen: p = 0.00224
Brain - Spinal cord (cervical c-1): p = 0.00397
Brain - Anterior cingulate cortex (BA24): p = 0.05
20003_1140876076Treatment/medication code: flixonase 50micrograms aqueous nasal sprayUK Biobank (UKBB)Neale Lab201814243597173Liver: p = 9.79E-4
Small Intestine - Terminal Ileum: p = 0.00384
Thyroid: p = 0.04
20003_1140911732Treatment/medication code: garlic productUK Biobank (UKBB)Neale Lab201848693562723Liver: p = 9.28E-4
Spleen: p = 0.00468
Brain - Amygdala: p = 0.03
20003_1140865654Treatment/medication code: codeine phosphate+kaolin 10mg/3g/10ml mixtureUK Biobank (UKBB)Neale Lab20181303610112Heart - Atrial Appendage: p = 8.73E-5
Heart - Left Ventricle: p = 0.00374
Ovary: p = 0.03
20003_1140872200Treatment/medication code: epilim 100mg crushable tabletUK Biobank (UKBB)Neale Lab20186123605293Minor Salivary Gland: p = 0.00494
Heart - Atrial Appendage: p = 0.00691
Brain - Amygdala: p = 0.01
20003_1140881856Treatment/medication code: salbutamolUK Biobank (UKBB)Neale Lab201843053568364Spleen: p = 7.19E-5
Lung: p = 1.24E-4
Small Intestine - Terminal Ileum: p = 0.00588
20003_1141190158Treatment/medication code: cipralex 5mg tabletUK Biobank (UKBB)Neale Lab20183223608193Muscle - Skeletal: p = 0.00482
Brain - Anterior cingulate cortex (BA24): p = 0.05
Brain - Cerebellar Hemisphere: p = 0.05
20003_2038460076Treatment/medication code: phenytoinUK Biobank (UKBB)Neale Lab20183443607972Adipose - Subcutaneous: p = 0.01
Brain - Hippocampus: p = 0.02
Brain - Amygdala: p = 0.03
20003_1140876136Treatment/medication code: beconase 50micrograms nasal sprayUK Biobank (UKBB)Neale Lab201824153587263Colon - Sigmoid: p = 0.02
Small Intestine - Terminal Ileum: p = 0.02
Lung: p = 0.02
20003_1140876404Treatment/medication code: aqueous cream bpUK Biobank (UKBB)Neale Lab20183063608353Liver: p = 0.00164
Kidney - Cortex: p = 0.00901
Brain - Nucleus accumbens (basal ganglia): p = 0.04
20003_1141176570Treatment/medication code: fosamax 5mg tabletUK Biobank (UKBB)Neale Lab20184403607012Artery - Coronary: p = 0.02
Colon - Transverse: p = 0.02
Pancreas: p = 0.05
20003_1140871266Treatment/medication code: arthrotec tabletUK Biobank (UKBB)Neale Lab20185183606233Uterus: p = 0.01
Esophagus - Muscularis: p = 0.02
Skin - Not Sun Exposed (Suprapubic): p = 0.02
20003_1140862476Treatment/medication code: beclazone 50 inhalerUK Biobank (UKBB)Neale Lab201810433600982Vagina: p = 0.01
Whole Blood: p = 0.01
Pancreas: p = 0.10
20003_1141168318Treatment/medication code: clopidogrelUK Biobank (UKBB)Neale Lab201822903588513Brain - Frontal Cortex (BA9): p = 0.00236
Pituitary: p = 0.00488
Brain - Anterior cingulate cortex (BA24): p = 0.0056
20003_1140911754Treatment/medication code: anadin tabletUK Biobank (UKBB)Neale Lab20182683608733Artery - Aorta: p = 0.00349
Liver: p = 0.01
Skin - Sun Exposed (Lower leg): p = 0.02
20003_1140865354Treatment/medication code: gaviscon liquidUK Biobank (UKBB)Neale Lab201818863592553Skin - Not Sun Exposed (Suprapubic): p = 0.00146
Adipose - Visceral (Omentum): p = 0.00236
Esophagus - Gastroesophageal Junction: p = 0.01
20003_1141192740Treatment/medication code: ezetrol 10mg tabletUK Biobank (UKBB)Neale Lab20186653604763Muscle - Skeletal: p = 0.005
Kidney - Cortex: p = 0.03
Pancreas: p = 0.03
20003_1140872228Treatment/medication code: gabapentinUK Biobank (UKBB)Neale Lab201816743594673Testis: p = 0.02
Brain - Amygdala: p = 0.11
Brain - Frontal Cortex (BA9): p = 0.11
20003_1141156846Treatment/medication code: amias 2mg tabletUK Biobank (UKBB)Neale Lab20183883607532Colon - Sigmoid: p = 0.01
Brain - Nucleus accumbens (basal ganglia): p = 0.06
Brain - Substantia nigra: p = 0.06
20003_1140852976Treatment/medication code: multivitaminsUK Biobank (UKBB)Neale Lab2018111483499933Pituitary: p = 0.00183
Prostate: p = 0.00993
Skin - Not Sun Exposed (Suprapubic): p = 0.00993
20003_1140883504Treatment/medication code: cetirizineUK Biobank (UKBB)Neale Lab201840703570713Kidney - Cortex: p = 0.02
Pituitary: p = 0.03
Muscle - Skeletal: p = 0.05
20003_1140882910Treatment/medication code: daktacort creamUK Biobank (UKBB)Neale Lab20182463608953Colon - Transverse: p = 0.01
Esophagus - Gastroesophageal Junction: p = 0.01
Esophagus - Muscularis: p = 0.01
20003_1140862776Treatment/medication code: clarityn 10mg tabletUK Biobank (UKBB)Neale Lab20183283608132Lung: p = 5.32E-4
Spleen: p = 0.04
Adipose - Subcutaneous: p = 0.04
20003_1141192736Treatment/medication code: ezetimibeUK Biobank (UKBB)Neale Lab201821323590095Liver: p = 1.27E-6
Spleen: p = 1.91E-4
Small Intestine - Terminal Ileum: p = 0.00588
20003_1141146188Treatment/medication code: latanoprostUK Biobank (UKBB)Neale Lab20187253604163Heart - Atrial Appendage: p = 0.00534
Brain - Spinal cord (cervical c-1): p = 0.00639
Heart - Left Ventricle: p = 0.03
20003_1140875336Treatment/medication code: nabumetoneUK Biobank (UKBB)Neale Lab20181803609613Lung: p = 1.81E-4
Esophagus - Mucosa: p = 0.00447
Breast - Mammary Tissue: p = 0.03
20003_1140875420Treatment/medication code: baclofenUK Biobank (UKBB)Neale Lab20183963607453Lung: p = 1.9E-5
Adipose - Visceral (Omentum): p = 0.02
Heart - Left Ventricle: p = 0.03
20003_1140874370Treatment/medication code: aciclovirUK Biobank (UKBB)Neale Lab20182863608552Skin - Sun Exposed (Lower leg): p = 0.00705
Heart - Left Ventricle: p = 0.01
Skin - Not Sun Exposed (Suprapubic): p = 0.04
20003_1140888502Treatment/medication code: amiodaroneUK Biobank (UKBB)Neale Lab20183173608242Artery - Aorta: p = 0.02
Skin - Not Sun Exposed (Suprapubic): p = 0.03
Minor Salivary Gland: p = 0.05
20003_1141171948Treatment/medication code: adcal 600mg chewable tabletUK Biobank (UKBB)Neale Lab201810513600903Vagina: p = 0.00374
Whole Blood: p = 0.01
Adrenal Gland: p = 0.03
20003_1140911682Treatment/medication code: selenium ace tabletUK Biobank (UKBB)Neale Lab20185033606382Adrenal Gland: p = 1.86E-5
Kidney - Cortex: p = 8.13E-4
Liver: p = 0.02
20003_1141177526Treatment/medication code: esomeprazoleUK Biobank (UKBB)Neale Lab201812043599373Esophagus - Muscularis: p = 0.00721
Esophagus - Gastroesophageal Junction: p = 0.02
Esophagus - Mucosa: p = 0.02
20003_1141179992Treatment/medication code: dovobet ointmentUK Biobank (UKBB)Neale Lab20184213607205Spleen: p = 6.16E-7
Lung: p = 2.06E-6
Whole Blood: p = 9.82E-6
20003_1140870422Treatment/medication code: folic acid productUK Biobank (UKBB)Neale Lab201830243581175Spleen: p = 1.65E-7
Lung: p = 5.13E-7
Whole Blood: p = 0.00251
20003_1140883066Treatment/medication code: insulin productUK Biobank (UKBB)Neale Lab201835453575965Spleen: p = 1.03E-8
Lung: p = 9.51E-6
Small Intestine - Terminal Ileum: p = 1.34E-4
20003_1140862772Treatment/medication code: loratadineUK Biobank (UKBB)Neale Lab201826243585173Stomach: p = 0.00968
Kidney - Cortex: p = 0.00968
Testis: p = 0.02
20003_1140863182Treatment/medication code: nitrazepamUK Biobank (UKBB)Neale Lab20182263609153Small Intestine - Terminal Ileum: p = 0.00478
Stomach: p = 0.00765
Liver: p = 0.04
20003_1141175690Treatment/medication code: actonel 5mg tabletUK Biobank (UKBB)Neale Lab20183013608403Brain - Cerebellar Hemisphere: p = 0.00288
Brain - Hippocampus: p = 0.00288
Brain - Anterior cingulate cortex (BA24): p = 0.00678
20003_1141150944Treatment/medication code: nasonex 0.05% aqueous nasal sprayUK Biobank (UKBB)Neale Lab201818263593153Esophagus - Gastroesophageal Junction: p = 0.00494
Brain - Frontal Cortex (BA9): p = 0.03
Brain - Hippocampus: p = 0.03
20003_1141192414Treatment/medication code: crestor 10mg tabletUK Biobank (UKBB)Neale Lab20182363609052Skin - Sun Exposed (Lower leg): p = 9.7E-4
Skin - Not Sun Exposed (Suprapubic): p = 0.00124
Vagina: p = 0.03
20003_1140884672Treatment/medication code: fludrocortisoneUK Biobank (UKBB)Neale Lab20181643609775Lung: p = 3.72E-6
Spleen: p = 7.65E-6
Whole Blood: p = 3.78E-5
20003_1140862572Treatment/medication code: budesonideUK Biobank (UKBB)Neale Lab20187613603803Nerve - Tibial: p = 0.02
Esophagus - Muscularis: p = 0.03
Adrenal Gland: p = 0.05
20003_1140870570Treatment/medication code: vitamin b12 preparationUK Biobank (UKBB)Neale Lab201811173600242Adipose - Subcutaneous: p = 0.02
Artery - Coronary: p = 0.02
Testis: p = 0.02
20003_1140882782Treatment/medication code: dermovate creamUK Biobank (UKBB)Neale Lab20185553605863Adipose - Subcutaneous: p = 0.00543
Adipose - Visceral (Omentum): p = 0.00543
Kidney - Cortex: p = 0.02
20003_1140879760Treatment/medication code: bisoprololUK Biobank (UKBB)Neale Lab201853043558373Uterus: p = 5.68E-4
Artery - Aorta: p = 0.00236
Artery - Tibial: p = 0.0056
20003_1140872290Treatment/medication code: lamotrigineUK Biobank (UKBB)Neale Lab20184473606943Heart - Atrial Appendage: p = 0.00102
Heart - Left Ventricle: p = 0.00102
Brain - Cortex: p = 0.00273
20003_1141180212Treatment/medication code: escitalopramUK Biobank (UKBB)Neale Lab20186533604882Colon - Transverse: p = 0.02
Liver: p = 0.03
Adipose - Subcutaneous: p = 0.06
20003_1140873394Treatment/medication code: doxycyclineUK Biobank (UKBB)Neale Lab20183243608173Artery - Coronary: p = 2.47E-4
Uterus: p = 0.00443
Artery - Tibial: p = 0.01
20003_1140925800Treatment/medication code: movicol oral powderUK Biobank (UKBB)Neale Lab201811313600103Liver: p = 0.00672
Colon - Sigmoid: p = 0.01
Brain - Anterior cingulate cortex (BA24): p = 0.02
20003_1141188658Treatment/medication code: asacol mr 400mg e/c tabletUK Biobank (UKBB)Neale Lab20181543609873Skin - Sun Exposed (Lower leg): p = 1.03E-4
Spleen: p = 1.24E-4
Skin - Not Sun Exposed (Suprapubic): p = 9.03E-4
20003_1140911730Treatment/medication code: flax oil tabletUK Biobank (UKBB)Neale Lab20185983605433Thyroid: p = 0.00398
Brain - Putamen (basal ganglia): p = 0.00914
Brain - Amygdala: p = 0.02
20003_1141146612Treatment/medication code: calceos chewable tabletUK Biobank (UKBB)Neale Lab20182033609383Esophagus - Gastroesophageal Junction: p = 0.02
Artery - Tibial: p = 0.02
Artery - Aorta: p = 0.07
20003_1140923572Treatment/medication code: adipine mr 10 m/r tabletUK Biobank (UKBB)Neale Lab20181343610073Breast - Mammary Tissue: p = 0.02
Brain - Substantia nigra: p = 0.03
Skin - Not Sun Exposed (Suprapubic): p = 0.04
20003_1141146138Treatment/medication code: lipitor 10mg tabletUK Biobank (UKBB)Neale Lab201825843585574Liver: p = 5.4E-7
Adrenal Gland: p = 0.00199
Prostate: p = 0.01
20003_1140870956Treatment/medication code: alfacalcidolUK Biobank (UKBB)Neale Lab20183073608343Uterus: p = 0.02
Stomach: p = 0.02
Skin - Not Sun Exposed (Suprapubic): p = 0.02
20003_1141192410Treatment/medication code: rosuvastatinUK Biobank (UKBB)Neale Lab201822273589143Liver: p = 0.00151
Testis: p = 0.03
Lung: p = 0.04
20003_1141157486Treatment/medication code: salbutamol productUK Biobank (UKBB)Neale Lab20185663605753Prostate: p = 0.00764
Esophagus - Muscularis: p = 0.01
Skin - Sun Exposed (Lower leg): p = 0.01
20003_1140879404Treatment/medication code: docusate sodiumUK Biobank (UKBB)Neale Lab20182943608472Heart - Atrial Appendage: p = 0.00392
Brain - Cerebellar Hemisphere: p = 0.0096
Heart - Left Ventricle: p = 0.0096
20003_1140879430Treatment/medication code: domperidoneUK Biobank (UKBB)Neale Lab20187223604192Esophagus - Gastroesophageal Junction: p = 0.02
Ovary: p = 0.02
Adipose - Visceral (Omentum): p = 0.03
20003_1140874420Treatment/medication code: quinineUK Biobank (UKBB)Neale Lab201824293587124Skin - Sun Exposed (Lower leg): p = 7.12E-4
Skin - Not Sun Exposed (Suprapubic): p = 0.00153
Pituitary: p = 0.00786
20003_1140875990Treatment/medication code: hypromelloseUK Biobank (UKBB)Neale Lab20186143605273Adipose - Subcutaneous: p = 9.99E-4
Stomach: p = 0.00265
Breast - Mammary Tissue: p = 0.00603
20003_1140866280Treatment/medication code: bumetanideUK Biobank (UKBB)Neale Lab20183003608413Lung: p = 0.01
Brain - Spinal cord (cervical c-1): p = 0.04
Heart - Left Ventricle: p = 0.06
20003_1140882236Treatment/medication code: seroxat 20mg tabletUK Biobank (UKBB)Neale Lab20184993606422Skin - Not Sun Exposed (Suprapubic): p = 0.00426
Skin - Sun Exposed (Lower leg): p = 0.00671
Brain - Caudate (basal ganglia): p = 0.02
20003_1140910548Treatment/medication code: iron sulphateUK Biobank (UKBB)Neale Lab20181703609713Brain - Nucleus accumbens (basal ganglia): p = 0.00426
Brain - Putamen (basal ganglia): p = 0.00426
Esophagus - Muscularis: p = 0.00426
20003_1140861088Treatment/medication code: nifedipineUK Biobank (UKBB)Neale Lab20188023603393Brain - Caudate (basal ganglia): p = 0.02
Vagina: p = 0.03
Brain - Spinal cord (cervical c-1): p = 0.04
20003_1140884444Treatment/medication code: codeineUK Biobank (UKBB)Neale Lab201818703592713Prostate: p = 0.01
Whole Blood: p = 0.02
Uterus: p = 0.02
20003_1140882800Treatment/medication code: eumovate creamUK Biobank (UKBB)Neale Lab20183963607453Artery - Coronary: p = 0.01
Brain - Nucleus accumbens (basal ganglia): p = 0.02
Prostate: p = 0.02
20003_1140864734Treatment/medication code: combivent inhalerUK Biobank (UKBB)Neale Lab20181593609822Skin - Sun Exposed (Lower leg): p = 2.8E-4
Skin - Not Sun Exposed (Suprapubic): p = 8.64E-4
Whole Blood: p = 0.02
20003_1140861276Treatment/medication code: lacidipineUK Biobank (UKBB)Neale Lab20183903607512Adipose - Visceral (Omentum): p = 0.02
Breast - Mammary Tissue: p = 0.02
Brain - Cerebellum: p = 0.04
20003_1140861954Treatment/medication code: fenofibrateUK Biobank (UKBB)Neale Lab20184883606534Nerve - Tibial: p = 0.00115
Liver: p = 0.02
Spleen: p = 0.03
20003_1140879464Treatment/medication code: loperamideUK Biobank (UKBB)Neale Lab201812033599383Colon - Sigmoid: p = 0.00128
Prostate: p = 0.00634
Pancreas: p = 0.02
20003_1140879658Treatment/medication code: chlorpromazineUK Biobank (UKBB)Neale Lab20181173610243Artery - Tibial: p = 0.02
Brain - Hypothalamus: p = 0.04
Artery - Aorta: p = 0.05
20003_1140923276Treatment/medication code: co-amilozideUK Biobank (UKBB)Neale Lab20182143609273Liver: p = 0.00984
Minor Salivary Gland: p = 0.05
Brain - Cerebellar Hemisphere: p = 0.08
20003_1140865426Treatment/medication code: cimetidineUK Biobank (UKBB)Neale Lab20182933608483Artery - Coronary: p = 0.03
Pituitary: p = 0.05
Adipose - Subcutaneous: p = 0.08
20003_1140867490Treatment/medication code: lithium productUK Biobank (UKBB)Neale Lab20183503607912Skin - Not Sun Exposed (Suprapubic): p = 0.0039
Skin - Sun Exposed (Lower leg): p = 0.00914
Brain - Spinal cord (cervical c-1): p = 0.02
20003_1140884700Treatment/medication code: trimovate ointmentUK Biobank (UKBB)Neale Lab20182383609032Artery - Coronary: p = 0.04
Adipose - Subcutaneous: p = 0.05
Colon - Sigmoid: p = 0.08
20003_1140923336Treatment/medication code: co-tenidoneUK Biobank (UKBB)Neale Lab20185323606093Breast - Mammary Tissue: p = 0.00115
Heart - Left Ventricle: p = 0.02
Pancreas: p = 0.03
20003_1141195232Treatment/medication code: budesonide+formoterolUK Biobank (UKBB)Neale Lab20182573608842Artery - Coronary: p = 0.00312
Colon - Sigmoid: p = 0.04
Adrenal Gland: p = 0.04
20003_1140863144Treatment/medication code: zopicloneUK Biobank (UKBB)Neale Lab201812653598762Heart - Atrial Appendage: p = 0.00228
Brain - Cerebellar Hemisphere: p = 0.00984
Skin - Not Sun Exposed (Suprapubic): p = 0.00984
20003_1140865382Treatment/medication code: merbentyl 10mg tabletUK Biobank (UKBB)Neale Lab20181153610263Stomach: p = 0.00447
Heart - Atrial Appendage: p = 0.00447
Breast - Mammary Tissue: p = 0.01
20003_1140865350Treatment/medication code: fybogel mebeverine sachetUK Biobank (UKBB)Neale Lab20185243606173Adipose - Visceral (Omentum): p = 0.00144
Adipose - Subcutaneous: p = 0.00885
Lung: p = 0.00885
20003_1140868772Treatment/medication code: didronel 200mg tabletUK Biobank (UKBB)Neale Lab20181283610133Pituitary: p = 0.01
Spleen: p = 0.03
Vagina: p = 0.03
20003_1140888098Treatment/medication code: fluticasoneUK Biobank (UKBB)Neale Lab201815783595633Brain - Substantia nigra: p = 0.00102
Brain - Hippocampus: p = 0.00247
Brain - Hypothalamus: p = 0.00424
20003_1140888648Treatment/medication code: pravastatinUK Biobank (UKBB)Neale Lab201817263594153Artery - Tibial: p = 8.25E-4
Artery - Coronary: p = 0.00371
Nerve - Tibial: p = 0.00494
20003_1140916288Treatment/medication code: efexor 37.5mg tabletUK Biobank (UKBB)Neale Lab20181903609513Brain - Spinal cord (cervical c-1): p = 0.00447
Small Intestine - Terminal Ileum: p = 0.02
Prostate: p = 0.02
20003_1140926922Treatment/medication code: antihistamine 60mg tabletUK Biobank (UKBB)Neale Lab20182583608833Kidney - Cortex: p = 0.00696
Brain - Cerebellar Hemisphere: p = 0.01
Brain - Cerebellum: p = 0.01
20003_1141168554Treatment/medication code: migraleve tabletUK Biobank (UKBB)Neale Lab20184853606562Heart - Left Ventricle: p = 0.01
Heart - Atrial Appendage: p = 0.02
Adrenal Gland: p = 0.02
20003_1141180148Treatment/medication code: arcoxia 60mg tabletUK Biobank (UKBB)Neale Lab20181323610092Spleen: p = 0.00127
Brain - Cerebellar Hemisphere: p = 0.00553
Adrenal Gland: p = 0.00553
20003_1140866078Treatment/medication code: indapamideUK Biobank (UKBB)Neale Lab201811523599893Whole Blood: p = 0.00193
Thyroid: p = 0.00744
Lung: p = 0.01
20003_1141146198Treatment/medication code: xalatan 0.005% eye dropsUK Biobank (UKBB)Neale Lab201810343601073Pituitary: p = 0.06
Whole Blood: p = 0.06
Colon - Sigmoid: p = 0.08
20003_1197Treatment/medication code: evening primrose oil productUK Biobank (UKBB)Neale Lab20188143603272Artery - Tibial: p = 2.6E-4
Artery - Coronary: p = 0.00231
Adipose - Visceral (Omentum): p = 0.00379
20003_1201Treatment/medication code: st john's wort/hypericum [ctsu]UK Biobank (UKBB)Neale Lab20186673604743Adrenal Gland: p = 0.00696
Skin - Sun Exposed (Lower leg): p = 0.00907
Skin - Not Sun Exposed (Suprapubic): p = 0.02
20003_1140872072Treatment/medication code: tegretol 100mg tabletUK Biobank (UKBB)Neale Lab20188133603282Brain - Cerebellar Hemisphere: p = 0.03
Brain - Cerebellum: p = 0.03
Lung: p = 0.05
20003_1140882776Treatment/medication code: fucibet creamUK Biobank (UKBB)Neale Lab20182073609342Liver: p = 0.01
Nerve - Tibial: p = 0.01
Minor Salivary Gland: p = 0.02
20003_1140874138Treatment/medication code: ciprofloxacinUK Biobank (UKBB)Neale Lab20181413610003Pituitary: p = 0.00586
Lung: p = 0.02
Colon - Transverse: p = 0.04
20003_2038459814Treatment/medication code: digoxinUK Biobank (UKBB)Neale Lab20189213602203Lung: p = 0.00385
Heart - Atrial Appendage: p = 0.02
Muscle - Skeletal: p = 0.03
20003_1140871462Treatment/medication code: naproxenUK Biobank (UKBB)Neale Lab201823383588033Brain - Caudate (basal ganglia): p = 4.02E-4
Brain - Nucleus accumbens (basal ganglia): p = 0.0011
Nerve - Tibial: p = 0.00178
20003_1140879620Treatment/medication code: clomipramineUK Biobank (UKBB)Neale Lab20182423608993Skin - Not Sun Exposed (Suprapubic): p = 0.00326
Minor Salivary Gland: p = 0.02
Skin - Sun Exposed (Lower leg): p = 0.02
20003_1140888560Treatment/medication code: perindoprilUK Biobank (UKBB)Neale Lab201851573559843Lung: p = 0.00436
Uterus: p = 0.01
Spleen: p = 0.01
20003_1141151946Treatment/medication code: cipramil 10mg tabletUK Biobank (UKBB)Neale Lab20181243610172Brain - Caudate (basal ganglia): p = 0.01
Brain - Nucleus accumbens (basal ganglia): p = 0.01
Brain - Putamen (basal ganglia): p = 0.01
20003_1141179914Treatment/medication code: bimatoprostUK Biobank (UKBB)Neale Lab20182203609212Pancreas: p = 0.00229
Nerve - Tibial: p = 0.00913
Prostate: p = 0.02
20003_1140883568Treatment/medication code: oxybutyninUK Biobank (UKBB)Neale Lab20188273603143Muscle - Skeletal: p = 0.00155
Adipose - Visceral (Omentum): p = 0.02
Esophagus - Gastroesophageal Junction: p = 0.02
20003_1141153242Treatment/medication code: balsalazide disodiumUK Biobank (UKBB)Neale Lab20181043610373Pituitary: p = 0.02
Skin - Sun Exposed (Lower leg): p = 0.03
Esophagus - Mucosa: p = 0.05
20003_1140863202Treatment/medication code: temazepamUK Biobank (UKBB)Neale Lab20187593603822Brain - Caudate (basal ganglia): p = 0.10
Lung: p = 0.13
Brain - Cerebellar Hemisphere: p = 0.18
20003_1140871024Treatment/medication code: vitamin b compound tabletUK Biobank (UKBB)Neale Lab201826193585222Pancreas: p = 0.02
Pituitary: p = 0.02
Liver: p = 0.03
20003_1141200564Treatment/medication code: duloxetineUK Biobank (UKBB)Neale Lab20183283608132Brain - Caudate (basal ganglia): p = 7.29E-4
Brain - Nucleus accumbens (basal ganglia): p = 0.00126
Brain - Putamen (basal ganglia): p = 0.00213
20003_1140874126Treatment/medication code: nitrofurantoinUK Biobank (UKBB)Neale Lab20182243609172Kidney - Cortex: p = 0.00689
Pituitary: p = 0.03
Nerve - Tibial: p = 0.03
20003_1141184726Treatment/medication code: xalacom 0.005%/0.5% eye dropsUK Biobank (UKBB)Neale Lab20182103609313Skin - Not Sun Exposed (Suprapubic): p = 6.39E-4
Skin - Sun Exposed (Lower leg): p = 6.39E-4
Adrenal Gland: p = 0.00126
20003_1140879842Treatment/medication code: propranololUK Biobank (UKBB)Neale Lab201824053587363Brain - Nucleus accumbens (basal ganglia): p = 6.35E-4
Brain - Caudate (basal ganglia): p = 0.00158
Brain - Hypothalamus: p = 0.00158
20003_1140883548Treatment/medication code: ipratropiumUK Biobank (UKBB)Neale Lab20184763606653Colon - Transverse: p = 0.02
Stomach: p = 0.02
Skin - Not Sun Exposed (Suprapubic): p = 0.05
20003_1140910832Treatment/medication code: sodium warfarinUK Biobank (UKBB)Neale Lab20183143608273Liver: p = 0.05
Artery - Aorta: p = 0.07
Colon - Transverse: p = 0.08
20003_1141150624Treatment/medication code: zomig 2.5mg tabletUK Biobank (UKBB)Neale Lab20183493607923Breast - Mammary Tissue: p = 0.03
Vagina: p = 0.04
Stomach: p = 0.07
20003_1199Treatment/medication code: food supplement/plant/herbal extractUK Biobank (UKBB)Neale Lab201813263598153Thyroid: p = 0.02
Heart - Atrial Appendage: p = 0.04
Prostate: p = 0.05
20003_1140884412Treatment/medication code: sumatriptanUK Biobank (UKBB)Neale Lab20189863601553Uterus: p = 0.00174
Heart - Atrial Appendage: p = 0.01
Brain - Hypothalamus: p = 0.02
20003_1140861138Treatment/medication code: adizem-60 m/r tabletUK Biobank (UKBB)Neale Lab20183223608193Colon - Transverse: p = 0.00108
Stomach: p = 0.00294
Adrenal Gland: p = 0.00414
20003_1140911658Treatment/medication code: imigran 50mg tabletUK Biobank (UKBB)Neale Lab20185903605513Esophagus - Mucosa: p = 9.31E-4
Pancreas: p = 0.00488
Artery - Tibial: p = 0.00929
20003_1141185326Treatment/medication code: travatan 40micrograms/ml eye dropsUK Biobank (UKBB)Neale Lab20182513608903Brain - Spinal cord (cervical c-1): p = 0.00691
Skin - Not Sun Exposed (Suprapubic): p = 0.02
Brain - Substantia nigra: p = 0.06
20003_1140879428Treatment/medication code: mebeverineUK Biobank (UKBB)Neale Lab201817983593433Adrenal Gland: p = 0.00417
Adipose - Visceral (Omentum): p = 0.02
Adipose - Subcutaneous: p = 0.04
20003_1141169520Treatment/medication code: cosopt 2%/0.5% eye dropsUK Biobank (UKBB)Neale Lab20183273608143Uterus: p = 0.009
Adrenal Gland: p = 0.05
Thyroid: p = 0.05
20003_1141176668Treatment/medication code: celebrex 100mg capsuleUK Biobank (UKBB)Neale Lab20182873608542Vagina: p = 0.0026
Esophagus - Mucosa: p = 0.00637
Colon - Transverse: p = 0.03
20003_1140865416Treatment/medication code: colpermin 0.2ml m/r gel e/c capsuleUK Biobank (UKBB)Neale Lab20183293608122Kidney - Cortex: p = 7.0E-4
Small Intestine - Terminal Ileum: p = 0.00505
Muscle - Skeletal: p = 0.01
20003_1141177532Treatment/medication code: nexium 20mg tabletUK Biobank (UKBB)Neale Lab20186413605002Prostate: p = 0.00349
Colon - Transverse: p = 0.00804
Vagina: p = 0.00806
20003_1140865578Treatment/medication code: mesalazineUK Biobank (UKBB)Neale Lab20185103606313Colon - Transverse: p = 2.37E-4
Kidney - Cortex: p = 0.00199
Uterus: p = 0.00199
20003_1140916282Treatment/medication code: venlafaxineUK Biobank (UKBB)Neale Lab201815333596083Breast - Mammary Tissue: p = 0.00626
Uterus: p = 0.01
Artery - Coronary: p = 0.02
20003_1141157418Treatment/medication code: budesonide productUK Biobank (UKBB)Neale Lab20181043610373Lung: p = 0.00862
Whole Blood: p = 0.05
Brain - Cerebellar Hemisphere: p = 0.08
20003_1141157294Treatment/medication code: hydrocortisone productUK Biobank (UKBB)Neale Lab20182573608843Skin - Sun Exposed (Lower leg): p = 0.00502
Skin - Not Sun Exposed (Suprapubic): p = 0.02
Testis: p = 0.03
20003_1140923348Treatment/medication code: co-proxamolUK Biobank (UKBB)Neale Lab20182903608513Brain - Cortex: p = 0.04
Esophagus - Mucosa: p = 0.04
Colon - Transverse: p = 0.04
20003_1140888538Treatment/medication code: zinc productUK Biobank (UKBB)Neale Lab201824203587213Adipose - Visceral (Omentum): p = 0.03
Ovary: p = 0.05
Artery - Tibial: p = 0.06
20003_1140862380Treatment/medication code: becloforte 250micrograms inhalerUK Biobank (UKBB)Neale Lab20181973609443Thyroid: p = 0.00462
Pituitary: p = 0.04
Brain - Cerebellum: p = 0.06
20003_1140884464Treatment/medication code: dihydrocodeineUK Biobank (UKBB)Neale Lab201812903598512Pancreas: p = 0.02
Artery - Aorta: p = 0.03
Spleen: p = 0.05
20003_1140888172Treatment/medication code: mometasoneUK Biobank (UKBB)Neale Lab20187093604322Muscle - Skeletal: p = 0.01
Brain - Cortex: p = 0.03
Brain - Frontal Cortex (BA9): p = 0.03
20003_1141152590Treatment/medication code: glimepirideUK Biobank (UKBB)Neale Lab20183193608223Vagina: p = 0.01
Esophagus - Mucosa: p = 0.03
Adrenal Gland: p = 0.04
20003_1140882618Treatment/medication code: diprosalic ointmentUK Biobank (UKBB)Neale Lab20181593609823Brain - Spinal cord (cervical c-1): p = 0.00153
Pancreas: p = 0.0039
Heart - Left Ventricle: p = 0.02
20003_1140888266Treatment/medication code: warfarinUK Biobank (UKBB)Neale Lab201836513574904Heart - Atrial Appendage: p = 3.04E-4
Colon - Sigmoid: p = 0.00226
Muscle - Skeletal: p = 0.00725
20003_1141178052Treatment/medication code: zapain capletUK Biobank (UKBB)Neale Lab20181333610083Skin - Not Sun Exposed (Suprapubic): p = 0.01
Colon - Sigmoid: p = 0.03
Esophagus - Gastroesophageal Junction: p = 0.03
20003_1140873966Treatment/medication code: trimethoprimUK Biobank (UKBB)Neale Lab20183753607663Skin - Not Sun Exposed (Suprapubic): p = 0.01
Skin - Sun Exposed (Lower leg): p = 0.01
Uterus: p = 0.02
20003_1140878304Treatment/medication code: e45 creamUK Biobank (UKBB)Neale Lab20182463608952Esophagus - Gastroesophageal Junction: p = 0.00881
Adipose - Subcutaneous: p = 0.05
Brain - Substantia nigra: p = 0.10
20003_1195Treatment/medication code: vitamin c productUK Biobank (UKBB)Neale Lab20189723601693Colon - Sigmoid: p = 0.00239
Prostate: p = 0.02
Vagina: p = 0.03
20003_1141180342Treatment/medication code: beclometasone dipropionate+salbutamolUK Biobank (UKBB)Neale Lab20182313609103Esophagus - Mucosa: p = 0.01
Spleen: p = 0.03
Brain - Amygdala: p = 0.05
20003_1140911734Treatment/medication code: ginkgo forte tabletUK Biobank (UKBB)Neale Lab201820733590683Colon - Transverse: p = 9.35E-4
Kidney - Cortex: p = 0.00241
Liver: p = 0.00577
20003_1141171496Treatment/medication code: trospiumUK Biobank (UKBB)Neale Lab20181823609592Adipose - Subcutaneous: p = 0.00254
Artery - Aorta: p = 0.01
Thyroid: p = 0.03
20003_1140871542Treatment/medication code: mefenamic acidUK Biobank (UKBB)Neale Lab20183883607533Small Intestine - Terminal Ileum: p = 0.00412
Esophagus - Muscularis: p = 0.03
Whole Blood: p = 0.03
20003_1140870862Treatment/medication code: calcichew forte 2.5g chewable tabletUK Biobank (UKBB)Neale Lab20183573607842Thyroid: p = 0.01
Brain - Spinal cord (cervical c-1): p = 0.03
Skin - Not Sun Exposed (Suprapubic): p = 0.03
20003_1140888570Treatment/medication code: flecainideUK Biobank (UKBB)Neale Lab20186043605373Vagina: p = 0.01
Whole Blood: p = 0.01
Esophagus - Mucosa: p = 0.02
20003_1140927086Treatment/medication code: arthrotec 50 tabletUK Biobank (UKBB)Neale Lab20183083608332Brain - Cortex: p = 0.01
Brain - Frontal Cortex (BA9): p = 0.03
Nerve - Tibial: p = 0.03
20003_1141152998Treatment/medication code: irbesartanUK Biobank (UKBB)Neale Lab201825743585673Kidney - Cortex: p = 0.00604
Small Intestine - Terminal Ileum: p = 0.03
Liver: p = 0.03
20003_1140875486Treatment/medication code: colchicineUK Biobank (UKBB)Neale Lab20181903609513Uterus: p = 0.01
Liver: p = 0.02
Brain - Amygdala: p = 0.03
20003_1140879634Treatment/medication code: trazodoneUK Biobank (UKBB)Neale Lab20185193606223Muscle - Skeletal: p = 0.00656
Brain - Cerebellar Hemisphere: p = 0.03
Whole Blood: p = 0.04
20003_1141153006Treatment/medication code: aprovel 75mg tabletUK Biobank (UKBB)Neale Lab20183113608303Skin - Not Sun Exposed (Suprapubic): p = 0.01
Brain - Spinal cord (cervical c-1): p = 0.02
Skin - Sun Exposed (Lower leg): p = 0.02
20003_1140873548Treatment/medication code: oxytetracyclineUK Biobank (UKBB)Neale Lab201810753600665Lung: p = 6.3E-5
Whole Blood: p = 0.0027
Spleen: p = 0.00656
20003_1140926606Treatment/medication code: salbutamol 100micrograms spacehalerUK Biobank (UKBB)Neale Lab201822673588743Lung: p = 0.0027
Colon - Transverse: p = 0.04
Whole Blood: p = 0.04
20003_1140923402Treatment/medication code: co-amilofruseUK Biobank (UKBB)Neale Lab20183573607842Pituitary: p = 0.06
Colon - Transverse: p = 0.07
Esophagus - Mucosa: p = 0.09
20003_1140909954Treatment/medication code: acyclovirUK Biobank (UKBB)Neale Lab20181163610253Brain - Amygdala: p = 2.79E-4
Brain - Caudate (basal ganglia): p = 2.79E-4
Brain - Putamen (basal ganglia): p = 2.79E-4
20003_1141176662Treatment/medication code: celecoxibUK Biobank (UKBB)Neale Lab20183863607553Skin - Not Sun Exposed (Suprapubic): p = 0.00574
Spleen: p = 0.01
Whole Blood: p = 0.03
20003_1141180226Treatment/medication code: amoxicillinUK Biobank (UKBB)Neale Lab20182933608483Stomach: p = 0.02
Brain - Substantia nigra: p = 0.02
Brain - Cerebellum: p = 0.05
20003_1140867888Treatment/medication code: paroxetineUK Biobank (UKBB)Neale Lab201812043599373Colon - Sigmoid: p = 0.04
Pituitary: p = 0.05
Brain - Caudate (basal ganglia): p = 0.11
20003_1140881446Treatment/medication code: proctosedyl ointmentUK Biobank (UKBB)Neale Lab20181663609753Muscle - Skeletal: p = 0.00671
Esophagus - Muscularis: p = 0.03
Heart - Atrial Appendage: p = 0.04
20003_1140873480Treatment/medication code: minocyclineUK Biobank (UKBB)Neale Lab20181613609803Small Intestine - Terminal Ileum: p = 0.00238
Heart - Atrial Appendage: p = 0.02
Vagina: p = 0.07
20003_1141176288Treatment/medication code: azopt 10mg/ml eye dropsUK Biobank (UKBB)Neale Lab20181603609813Pituitary: p = 0.00282
Artery - Aorta: p = 0.00446
Artery - Tibial: p = 0.05
20003_1141180936Treatment/medication code: calcium carbonate+colecalciferol 1.25g/5micrograms tabletUK Biobank (UKBB)Neale Lab20181593609823Prostate: p = 0.03
Whole Blood: p = 0.08
Lung: p = 0.09
20003_1141194224Treatment/medication code: allergy relief antihistamine 4mg tabletUK Biobank (UKBB)Neale Lab20181503609913Adrenal Gland: p = 0.01
Adipose - Visceral (Omentum): p = 0.02
Adipose - Subcutaneous: p = 0.02
20003_1141152732Treatment/medication code: mirtazapineUK Biobank (UKBB)Neale Lab20189833601583Thyroid: p = 0.00578
Artery - Aorta: p = 0.01
Liver: p = 0.03
20003_1141182632Treatment/medication code: spiriva 18micrograms inhalation capsuleUK Biobank (UKBB)Neale Lab20185393606023Pancreas: p = 0.01
Brain - Spinal cord (cervical c-1): p = 0.02
Nerve - Tibial: p = 0.02
20003_1140867504Treatment/medication code: priadel 200mg m/r tabletUK Biobank (UKBB)Neale Lab20182483608933Vagina: p = 0.00264
Nerve - Tibial: p = 0.0042
Prostate: p = 0.01
20003_1140877892Treatment/medication code: voltarol emulgelUK Biobank (UKBB)Neale Lab20182233609183Adrenal Gland: p = 0.00374
Brain - Cerebellar Hemisphere: p = 0.07
Stomach: p = 0.10
20003_1141167932Treatment/medication code: rizatriptanUK Biobank (UKBB)Neale Lab20182923608493Uterus: p = 0.00169
Kidney - Cortex: p = 0.00293
Colon - Transverse: p = 0.00726
20003_1140926780Treatment/medication code: adizem-xl plus m/r capsuleUK Biobank (UKBB)Neale Lab20182613608803Skin - Sun Exposed (Lower leg): p = 0.00362
Kidney - Cortex: p = 0.00488
Thyroid: p = 0.00488
20003_1140872112Treatment/medication code: epanutin 25mg capsuleUK Biobank (UKBB)Neale Lab20182693608723Brain - Anterior cingulate cortex (BA24): p = 0.02
Brain - Cerebellar Hemisphere: p = 0.03
Brain - Cerebellum: p = 0.03
20003_1141146508Treatment/medication code: nasacort 55micrograms aqueous nasal sprayUK Biobank (UKBB)Neale Lab20181763609653Prostate: p = 0.02
Kidney - Cortex: p = 0.08
Pancreas: p = 0.08
20003_1140871732Treatment/medication code: buprenorphineUK Biobank (UKBB)Neale Lab20182403609013Prostate: p = 0.02
Artery - Coronary: p = 0.03
Esophagus - Gastroesophageal Junction: p = 0.06
20003_1140870954Treatment/medication code: vitamin d productUK Biobank (UKBB)Neale Lab201810143601273Small Intestine - Terminal Ileum: p = 0.00102
Kidney - Cortex: p = 0.00291
Artery - Tibial: p = 0.00472
20003_1140874014Treatment/medication code: metronidazoleUK Biobank (UKBB)Neale Lab20181383610033Kidney - Cortex: p = 0.02
Nerve - Tibial: p = 0.02
Skin - Sun Exposed (Lower leg): p = 0.02
20003_1140874930Treatment/medication code: prednisoloneUK Biobank (UKBB)Neale Lab201821033590384Lung: p = 3.56E-7
Spleen: p = 1.91E-4
Whole Blood: p = 0.00183
20003_1140911640Treatment/medication code: lecithin productUK Biobank (UKBB)Neale Lab20182133609283Heart - Left Ventricle: p = 6.71E-4
Vagina: p = 0.00308
Heart - Atrial Appendage: p = 0.00462
20003_1140883524Treatment/medication code: cinnarizineUK Biobank (UKBB)Neale Lab20181933609482Pituitary: p = 0.00929
Brain - Hypothalamus: p = 0.06
Artery - Aorta: p = 0.07
20003_1141168684Treatment/medication code: xenical 120mg capsuleUK Biobank (UKBB)Neale Lab20183243608173Skin - Not Sun Exposed (Suprapubic): p = 0.02
Pituitary: p = 0.09
Ovary: p = 0.14
20003_1140874866Treatment/medication code: carbimazoleUK Biobank (UKBB)Neale Lab20182893608525Lung: p = 4.67E-6
Spleen: p = 5.4E-5
Small Intestine - Terminal Ileum: p = 2.52E-4
20003_1140865564Treatment/medication code: imodium 2mg capsuleUK Biobank (UKBB)Neale Lab20181993609423Pituitary: p = 0.02
Skin - Not Sun Exposed (Suprapubic): p = 0.02
Skin - Sun Exposed (Lower leg): p = 0.02
20003_1141166294Treatment/medication code: leflunomideUK Biobank (UKBB)Neale Lab20181623609793Lung: p = 4.34E-4
Small Intestine - Terminal Ileum: p = 0.02
Brain - Amygdala: p = 0.07
20003_1141176732Treatment/medication code: carbomersUK Biobank (UKBB)Neale Lab20182743608673Esophagus - Muscularis: p = 0.00678
Esophagus - Gastroesophageal Junction: p = 0.06
Heart - Atrial Appendage: p = 0.11
20003_1140909368Treatment/medication code: carvedilolUK Biobank (UKBB)Neale Lab20182483608933Thyroid: p = 0.00599
Colon - Transverse: p = 0.04
Heart - Atrial Appendage: p = 0.04
20003_1141168680Treatment/medication code: orlistatUK Biobank (UKBB)Neale Lab20184143607273Skin - Not Sun Exposed (Suprapubic): p = 0.00482
Skin - Sun Exposed (Lower leg): p = 0.00745
Artery - Tibial: p = 0.01
20003_1140873608Treatment/medication code: erythromycinUK Biobank (UKBB)Neale Lab20182843608573Nerve - Tibial: p = 0.02
Ovary: p = 0.04
Spleen: p = 0.04
20003_1140911736Treatment/medication code: ginseng productUK Biobank (UKBB)Neale Lab20185413606003Pituitary: p = 0.03
Brain - Substantia nigra: p = 0.04
Brain - Anterior cingulate cortex (BA24): p = 0.06
20003_1141200384Treatment/medication code: vesicare 5mg tabletUK Biobank (UKBB)Neale Lab20183553607863Kidney - Cortex: p = 0.00862
Small Intestine - Terminal Ileum: p = 0.02
Brain - Substantia nigra: p = 0.03
20003_1140861166Treatment/medication code: dilzem sr 60mg long acting m/r capsuleUK Biobank (UKBB)Neale Lab20181663609753Brain - Caudate (basal ganglia): p = 0.00513
Stomach: p = 0.02
Ovary: p = 0.02
20003_1140865800Treatment/medication code: lactulose productUK Biobank (UKBB)Neale Lab20189543601873Testis: p = 0.02
Skin - Sun Exposed (Lower leg): p = 0.03
Adrenal Gland: p = 0.04
20003_1140881882Treatment/medication code: timoptol 0.25% eye dropsUK Biobank (UKBB)Neale Lab20182293609122Breast - Mammary Tissue: p = 0.01
Whole Blood: p = 0.01
Adipose - Visceral (Omentum): p = 0.04
20003_1140928916Treatment/medication code: olanzapineUK Biobank (UKBB)Neale Lab20184053607363Spleen: p = 9.78E-4
Lung: p = 0.00404
Adipose - Subcutaneous: p = 0.02
20003_1141150620Treatment/medication code: zolmitriptanUK Biobank (UKBB)Neale Lab20183453607963Brain - Cortex: p = 0.00397
Brain - Hippocampus: p = 0.00881
Brain - Spinal cord (cervical c-1): p = 0.01
20003_1140909578Treatment/medication code: losec 10mg capsuleUK Biobank (UKBB)Neale Lab20182723608693Breast - Mammary Tissue: p = 0.02
Esophagus - Muscularis: p = 0.03
Vagina: p = 0.04
20003_1140875840Treatment/medication code: timolol 0.25% eye dropsUK Biobank (UKBB)Neale Lab20182703608713Breast - Mammary Tissue: p = 4.72E-4
Nerve - Tibial: p = 0.01
Adipose - Visceral (Omentum): p = 0.02
20003_1140878036Treatment/medication code: diclofenac sodium+misoprostolUK Biobank (UKBB)Neale Lab20182513608902Thyroid: p = 0.02
Esophagus - Gastroesophageal Junction: p = 0.02
Small Intestine - Terminal Ileum: p = 0.06
20003_1140909936Treatment/medication code: indometacinUK Biobank (UKBB)Neale Lab20182493608923Lung: p = 0.02
Small Intestine - Terminal Ileum: p = 0.03
Thyroid: p = 0.03
20003_1140880086Treatment/medication code: calcipotriolUK Biobank (UKBB)Neale Lab20182193609225Lung: p = 8.01E-7
Spleen: p = 4.45E-6
Whole Blood: p = 4.47E-4
20003_1140866800Treatment/medication code: half-inderal la 80mg m/r capsuleUK Biobank (UKBB)Neale Lab20181483609933Testis: p = 0.01
Brain - Amygdala: p = 0.02
Brain - Anterior cingulate cortex (BA24): p = 0.02
20003_1140884308Treatment/medication code: hydroxychloroquineUK Biobank (UKBB)Neale Lab20185173606243Lung: p = 0.0014
Spleen: p = 0.0014
Whole Blood: p = 0.00274
20003_1141171932Treatment/medication code: levetiracetamUK Biobank (UKBB)Neale Lab20181683609733Colon - Transverse: p = 0.02
Brain - Cerebellum: p = 0.06
Testis: p = 0.08
20003_1141187230Treatment/medication code: care cetirizine hayfever relief 10mg tabletUK Biobank (UKBB)Neale Lab20181053610363Brain - Spinal cord (cervical c-1): p = 0.006
Small Intestine - Terminal Ileum: p = 0.00853
Brain - Substantia nigra: p = 0.02
20003_1140888594Treatment/medication code: fluvastatinUK Biobank (UKBB)Neale Lab20181743609672Skin - Sun Exposed (Lower leg): p = 0.00435
Skin - Not Sun Exposed (Suprapubic): p = 0.02
Minor Salivary Gland: p = 0.03
20003_1141179920Treatment/medication code: lumigan 0.3mg/ml eye dropsUK Biobank (UKBB)Neale Lab20182483608932Pancreas: p = 0.02
Skin - Sun Exposed (Lower leg): p = 0.02
Spleen: p = 0.07
20003_1140917034Treatment/medication code: airomir 100micrograms cfc-free inhalerUK Biobank (UKBB)Neale Lab20181653609763Skin - Not Sun Exposed (Suprapubic): p = 0.00543
Skin - Sun Exposed (Lower leg): p = 0.00543
Artery - Coronary: p = 0.00968
20003_1140888512Treatment/medication code: amilorideUK Biobank (UKBB)Neale Lab20181263610153Liver: p = 0.00355
Esophagus - Gastroesophageal Junction: p = 0.00592
Esophagus - Muscularis: p = 0.00592
20003_1140865716Treatment/medication code: sennaUK Biobank (UKBB)Neale Lab20186983604433Breast - Mammary Tissue: p = 0.04
Brain - Hypothalamus: p = 0.04
Brain - Spinal cord (cervical c-1): p = 0.04
20003_1141200322Treatment/medication code: solifenacinUK Biobank (UKBB)Neale Lab20185713605703Brain - Hypothalamus: p = 0.01
Brain - Spinal cord (cervical c-1): p = 0.02
Stomach: p = 0.04
20003_1140879494Treatment/medication code: metoclopramideUK Biobank (UKBB)Neale Lab20184413607003Ovary: p = 0.00151
Brain - Cerebellar Hemisphere: p = 0.00532
Brain - Cerebellum: p = 0.00532
20003_1140879628Treatment/medication code: dothiepinUK Biobank (UKBB)Neale Lab20181483609933Esophagus - Mucosa: p = 0.01
Vagina: p = 0.03
Lung: p = 0.04
20003_1141180392Treatment/medication code: cefalexinUK Biobank (UKBB)Neale Lab20182073609342Kidney - Cortex: p = 6.42E-4
Thyroid: p = 6.42E-4
Skin - Sun Exposed (Lower leg): p = 0.00795
20003_1140875392Treatment/medication code: plaquenil 200mg tabletUK Biobank (UKBB)Neale Lab20181643609773Vagina: p = 0.00118
Pancreas: p = 0.02
Uterus: p = 0.04
20003_1141172924Treatment/medication code: desloratadineUK Biobank (UKBB)Neale Lab20184793606623Artery - Aorta: p = 0.00413
Liver: p = 0.00413
Artery - Coronary: p = 0.00641
20003_1140866026Treatment/medication code: creon e/c granules in capsuleUK Biobank (UKBB)Neale Lab20182043609373Esophagus - Muscularis: p = 0.03
Heart - Atrial Appendage: p = 0.03
Minor Salivary Gland: p = 0.03
20003_1140871472Treatment/medication code: naprosyn 250mg tabletUK Biobank (UKBB)Neale Lab20182423608992Stomach: p = 0.03
Brain - Substantia nigra: p = 0.11
Muscle - Skeletal: p = 0.11
20003_1141184748Treatment/medication code: levocetirizineUK Biobank (UKBB)Neale Lab20182313609102Colon - Transverse: p = 0.00639
Brain - Frontal Cortex (BA9): p = 0.03
Brain - Anterior cingulate cortex (BA24): p = 0.04
20003_1141164060Treatment/medication code: pramipexoleUK Biobank (UKBB)Neale Lab20181803609612Breast - Mammary Tissue: p = 0.04
Artery - Coronary: p = 0.04
Liver: p = 0.08
20003_1141157458Treatment/medication code: hypromellose productUK Biobank (UKBB)Neale Lab20182103609313Liver: p = 0.02
Skin - Not Sun Exposed (Suprapubic): p = 0.02
Breast - Mammary Tissue: p = 0.04
20003_1140909708Treatment/medication code: furosemideUK Biobank (UKBB)Neale Lab201827143584273Whole Blood: p = 5.24E-4
Adipose - Subcutaneous: p = 0.00311
Artery - Coronary: p = 0.05
20003_1140867876Treatment/medication code: prozac 20mg capsuleUK Biobank (UKBB)Neale Lab20184913606502Esophagus - Mucosa: p = 0.02
Brain - Hypothalamus: p = 0.04
Skin - Not Sun Exposed (Suprapubic): p = 0.04
20003_1141172492Treatment/medication code: micardis 20mg tabletUK Biobank (UKBB)Neale Lab20181093610322Brain - Substantia nigra: p = 0.00308
Artery - Tibial: p = 0.00795
Muscle - Skeletal: p = 0.01
20003_1140865786Treatment/medication code: bisacodylUK Biobank (UKBB)Neale Lab20181403610013Brain - Spinal cord (cervical c-1): p = 0.00934
Esophagus - Gastroesophageal Junction: p = 0.00934
Adrenal Gland: p = 0.02
20003_1140909766Treatment/medication code: multivitamins capsuleUK Biobank (UKBB)Neale Lab20182883608533Liver: p = 0.00136
Brain - Cerebellar Hemisphere: p = 0.00527
Brain - Cerebellum: p = 0.01
20003_1141145812Treatment/medication code: minerals - magnesiumUK Biobank (UKBB)Neale Lab20187743603673Colon - Transverse: p = 7.88E-4
Spleen: p = 0.01
Thyroid: p = 0.02
20003_1140866804Treatment/medication code: inderal 10mg tabletUK Biobank (UKBB)Neale Lab20181053610362Brain - Substantia nigra: p = 0.01
Adipose - Visceral (Omentum): p = 0.02
Brain - Hippocampus: p = 0.04
20003_1140909788Treatment/medication code: sodium cromoglicateUK Biobank (UKBB)Neale Lab20183103608313Breast - Mammary Tissue: p = 0.03
Whole Blood: p = 0.03
Liver: p = 0.05
20003_1140874686Treatment/medication code: glucophage 500mg tabletUK Biobank (UKBB)Neale Lab20183283608133Esophagus - Mucosa: p = 0.00634
Vagina: p = 0.00634
Brain - Hypothalamus: p = 0.01
20003_1140928004Treatment/medication code: zimovane ls 3.75mg tabletUK Biobank (UKBB)Neale Lab20181333610083Colon - Transverse: p = 0.00216
Ovary: p = 0.01
Vagina: p = 0.02
20003_1140883468Treatment/medication code: clonidineUK Biobank (UKBB)Neale Lab20184633606783Brain - Cortex: p = 0.02
Thyroid: p = 0.03
Uterus: p = 0.03
20003_1141172928Treatment/medication code: neoclarityn 5mg tabletUK Biobank (UKBB)Neale Lab20184343607073Small Intestine - Terminal Ileum: p = 0.00957
Esophagus - Gastroesophageal Junction: p = 0.03
Pancreas: p = 0.04
20003_1140864184Treatment/medication code: dovonex 50micrograms/g creamUK Biobank (UKBB)Neale Lab20182223609195Lung: p = 6.52E-5
Spleen: p = 3.98E-4
Whole Blood: p = 0.0021
20003_1140909790Treatment/medication code: chlorphenamineUK Biobank (UKBB)Neale Lab20182173609243Pancreas: p = 0.00846
Kidney - Cortex: p = 0.01
Artery - Tibial: p = 0.03
20003_1140858452Treatment/medication code: hepacon b12 1mg/1ml injectionUK Biobank (UKBB)Neale Lab20181613609802Lung: p = 0.04
Brain - Cerebellum: p = 0.06
Colon - Transverse: p = 0.06
20003_1141174032Treatment/medication code: doublebase gelUK Biobank (UKBB)Neale Lab20181873609543Pancreas: p = 0.03
Thyroid: p = 0.03
Esophagus - Mucosa: p = 0.04
20003_1140877826Treatment/medication code: sodium bicarbonateUK Biobank (UKBB)Neale Lab20181073610343Brain - Cortex: p = 0.00232
Brain - Anterior cingulate cortex (BA24): p = 0.00377
Brain - Frontal Cortex (BA9): p = 0.00936
20003_1141192916Treatment/medication code: rino clenil 50micrograms nasal sprayUK Biobank (UKBB)Neale Lab20186983604433Brain - Caudate (basal ganglia): p = 0.01
Brain - Cerebellar Hemisphere: p = 0.01
Brain - Putamen (basal ganglia): p = 0.01
20003_1141200108Treatment/medication code: cymalon cranberry 1.5g/5ml liquidUK Biobank (UKBB)Neale Lab20181313610102Adipose - Subcutaneous: p = 0.02
Adipose - Visceral (Omentum): p = 0.03
Brain - Spinal cord (cervical c-1): p = 0.03
20003_1140879644Treatment/medication code: amantadineUK Biobank (UKBB)Neale Lab20181133610283Brain - Caudate (basal ganglia): p = 0.03
Brain - Amygdala: p = 0.04
Kidney - Cortex: p = 0.04
20003_1140888092Treatment/medication code: elocon creamUK Biobank (UKBB)Neale Lab20182403609013Heart - Atrial Appendage: p = 0.02
Esophagus - Mucosa: p = 0.03
Testis: p = 0.04
20003_1140877630Treatment/medication code: calcium+ergocalciferol tabletUK Biobank (UKBB)Neale Lab20181593609823Pituitary: p = 0.01
Minor Salivary Gland: p = 0.03
Brain - Spinal cord (cervical c-1): p = 0.04
20003_1140862944Treatment/medication code: carbocisteineUK Biobank (UKBB)Neale Lab20181933609483Heart - Atrial Appendage: p = 9.48E-4
Small Intestine - Terminal Ileum: p = 0.03
Esophagus - Muscularis: p = 0.04
20003_1140883748Treatment/medication code: selenium productUK Biobank (UKBB)Neale Lab201811303600112Liver: p = 0.01
Muscle - Skeletal: p = 0.03
Esophagus - Mucosa: p = 0.05
20003_1140862266Treatment/medication code: phyllocontin continus 225mg m/r tabletUK Biobank (UKBB)Neale Lab20181423609992Skin - Sun Exposed (Lower leg): p = 0.03
Colon - Transverse: p = 0.07
Pancreas: p = 0.08
20003_1140872036Treatment/medication code: paramax tabletUK Biobank (UKBB)Neale Lab20181293610123Liver: p = 0.04
Spleen: p = 0.04
Vagina: p = 0.04
20003_1140879806Treatment/medication code: diltiazemUK Biobank (UKBB)Neale Lab20187383604033Esophagus - Gastroesophageal Junction: p = 0.00406
Esophagus - Muscularis: p = 0.00874
Uterus: p = 0.00874
20003_1141168590Treatment/medication code: pariet 10mg e/c tabletUK Biobank (UKBB)Neale Lab20182393609023Adipose - Subcutaneous: p = 0.01
Liver: p = 0.01
Skin - Sun Exposed (Lower leg): p = 0.03
20003_1140927328Treatment/medication code: terbinafineUK Biobank (UKBB)Neale Lab20187003604412Muscle - Skeletal: p = 0.0055
Minor Salivary Gland: p = 0.02
Stomach: p = 0.03
20003_1140882626Treatment/medication code: betnesol 0.1% eye/ear/nose dropsUK Biobank (UKBB)Neale Lab20181223610192Stomach: p = 0.00968
Artery - Tibial: p = 0.02
Colon - Transverse: p = 0.03
20003_1141185316Treatment/medication code: travoprostUK Biobank (UKBB)Neale Lab20181413610003Testis: p = 0.00199
Skin - Not Sun Exposed (Suprapubic): p = 0.00285
Skin - Sun Exposed (Lower leg): p = 0.00713
20003_1141176670Treatment/medication code: celebrex 200mg capsuleUK Biobank (UKBB)Neale Lab20181403610013Brain - Putamen (basal ganglia): p = 6.57E-4
Brain - Substantia nigra: p = 0.0019
Brain - Cerebellum: p = 0.00313
20003_1141169844Treatment/medication code: dexamethasone+hypromellose 0.1%/0.5% eye dropsUK Biobank (UKBB)Neale Lab20181503609913Stomach: p = 0.04
Liver: p = 0.07
Pituitary: p = 0.08
20003_1140862086Treatment/medication code: salamol 100micrograms inhalerUK Biobank (UKBB)Neale Lab201811123600293Brain - Frontal Cortex (BA9): p = 0.00165
Thyroid: p = 0.00236
Brain - Caudate (basal ganglia): p = 0.00267
20003_1141194386Treatment/medication code: telfast 30 tabletUK Biobank (UKBB)Neale Lab20182673608742Muscle - Skeletal: p = 1.11E-4
Adrenal Gland: p = 0.00935
Vagina: p = 0.00935
20003_1140926732Treatment/medication code: meloxicamUK Biobank (UKBB)Neale Lab201810383601033Testis: p = 0.01
Brain - Cerebellar Hemisphere: p = 0.02
Brain - Spinal cord (cervical c-1): p = 0.02
20003_1141200004Treatment/medication code: pregabalinUK Biobank (UKBB)Neale Lab20187603603813Artery - Coronary: p = 0.00157
Skin - Sun Exposed (Lower leg): p = 0.00922
Minor Salivary Gland: p = 0.03
20003_1140864992Treatment/medication code: tramadolUK Biobank (UKBB)Neale Lab201840113571303Skin - Sun Exposed (Lower leg): p = 0.00845
Skin - Not Sun Exposed (Suprapubic): p = 0.02
Spleen: p = 0.03
20003_1140873474Treatment/medication code: lymecyclineUK Biobank (UKBB)Neale Lab20181833609583Breast - Mammary Tissue: p = 0.04
Heart - Atrial Appendage: p = 0.04
Adrenal Gland: p = 0.04
20003_1140883664Treatment/medication code: pizotifenUK Biobank (UKBB)Neale Lab20185653605763Artery - Tibial: p = 0.00488
Esophagus - Muscularis: p = 0.00488
Kidney - Cortex: p = 0.03
20003_1140882498Treatment/medication code: penicillinUK Biobank (UKBB)Neale Lab20182183609232Adipose - Visceral (Omentum): p = 0.00294
Breast - Mammary Tissue: p = 0.04
Adipose - Subcutaneous: p = 0.05
20003_1141193346Treatment/medication code: olmetec 10mg tabletUK Biobank (UKBB)Neale Lab20182153609263Colon - Sigmoid: p = 0.00849
Brain - Hippocampus: p = 0.02
Vagina: p = 0.02
20003_1140874896Treatment/medication code: hydrocortisoneUK Biobank (UKBB)Neale Lab20186663604753Whole Blood: p = 0.00301
Spleen: p = 0.01
Vagina: p = 0.01
20003_1140879854Treatment/medication code: sotalolUK Biobank (UKBB)Neale Lab20185813605603Uterus: p = 0.00609
Colon - Sigmoid: p = 0.04
Skin - Not Sun Exposed (Suprapubic): p = 0.04
20003_1140860750Treatment/medication code: captoprilUK Biobank (UKBB)Neale Lab20181653609763Brain - Cerebellar Hemisphere: p = 0.05
Whole Blood: p = 0.05
Small Intestine - Terminal Ileum: p = 0.05
20003_1141182628Treatment/medication code: tiotropiumUK Biobank (UKBB)Neale Lab20189223602193Pancreas: p = 0.01
Uterus: p = 0.02
Stomach: p = 0.03
20003_1141166006Treatment/medication code: telmisartanUK Biobank (UKBB)Neale Lab20185823605593Nerve - Tibial: p = 0.02
Lung: p = 0.07
Spleen: p = 0.07
20003_1140873450Treatment/medication code: tetracyclineUK Biobank (UKBB)Neale Lab20181053610363Adrenal Gland: p = 0.02
Small Intestine - Terminal Ileum: p = 0.03
Lung: p = 0.05
20003_1140923688Treatment/medication code: zoton 15mg capsuleUK Biobank (UKBB)Neale Lab20182643608772Brain - Caudate (basal ganglia): p = 0.08
Pituitary: p = 0.11
Colon - Transverse: p = 0.14
20003_1141176284Treatment/medication code: brinzolamideUK Biobank (UKBB)Neale Lab20181353610063Liver: p = 0.00784
Colon - Transverse: p = 0.04
Brain - Anterior cingulate cortex (BA24): p = 0.05
20003_1140928274Treatment/medication code: ropiniroleUK Biobank (UKBB)Neale Lab20182653608763Small Intestine - Terminal Ileum: p = 0.02
Lung: p = 0.03
Pituitary: p = 0.03
20003_1140851088Treatment/medication code: senokot 7.5mg tabletUK Biobank (UKBB)Neale Lab20181743609672Heart - Atrial Appendage: p = 0.00929
Small Intestine - Terminal Ileum: p = 0.02
Pituitary: p = 0.04
20003_1141188146Treatment/medication code: simvador 10mg tabletUK Biobank (UKBB)Neale Lab20185173606243Vagina: p = 0.00843
Artery - Aorta: p = 0.02
Colon - Sigmoid: p = 0.02
20003_1141193282Treatment/medication code: olmesartanUK Biobank (UKBB)Neale Lab20184543606873Uterus: p = 0.00674
Breast - Mammary Tissue: p = 0.03
Adrenal Gland: p = 0.03
20003_2038460068Treatment/medication code: phenobarbitoneUK Biobank (UKBB)Neale Lab20181053610363Heart - Atrial Appendage: p = 0.02
Heart - Left Ventricle: p = 0.03
Adrenal Gland: p = 0.12
20003_1141171152Treatment/medication code: cardicor 1.25mg tabletUK Biobank (UKBB)Neale Lab20183413608003Brain - Anterior cingulate cortex (BA24): p = 0.00183
Uterus: p = 0.00566
Brain - Amygdala: p = 0.00993
20003_1141146606Treatment/medication code: calcium carbonate+cholecalciferol 1.25g/200iu tabletUK Biobank (UKBB)Neale Lab20185573605843Liver: p = 0.01
Pituitary: p = 0.08
Thyroid: p = 0.08
20003_1141152848Treatment/medication code: quetiapineUK Biobank (UKBB)Neale Lab20182273609143Ovary: p = 0.00516
Adipose - Subcutaneous: p = 0.03
Adipose - Visceral (Omentum): p = 0.04
20003_1140881472Treatment/medication code: lacri-lube eye ointmentUK Biobank (UKBB)Neale Lab20185113606303Liver: p = 0.02
Ovary: p = 0.03
Breast - Mammary Tissue: p = 0.04
20003_1141168584Treatment/medication code: rabeprazole sodiumUK Biobank (UKBB)Neale Lab20186673604743Brain - Amygdala: p = 0.00578
Brain - Cerebellar Hemisphere: p = 0.00578
Brain - Cortex: p = 0.01
20003_1140860834Treatment/medication code: glyceryl trinitrateUK Biobank (UKBB)Neale Lab201811113600303Brain - Cortex: p = 0.0075
Brain - Spinal cord (cervical c-1): p = 0.0075
Brain - Substantia nigra: p = 0.0075
20003_1141180150Treatment/medication code: arcoxia 90mg tabletUK Biobank (UKBB)Neale Lab20181023610393Artery - Coronary: p = 0.00236
Esophagus - Muscularis: p = 0.02
Artery - Aorta: p = 0.05
20003_1140868170Treatment/medication code: prochlorperazineUK Biobank (UKBB)Neale Lab20185213606203Adrenal Gland: p = 0.00543
Brain - Caudate (basal ganglia): p = 0.04
Brain - Spinal cord (cervical c-1): p = 0.04
20003_1140883476Treatment/medication code: procyclidineUK Biobank (UKBB)Neale Lab20181543609873Artery - Aorta: p = 0.04
Brain - Anterior cingulate cortex (BA24): p = 0.05
Thyroid: p = 0.05
20003_1141187776Treatment/medication code: nurofen 200mg tabletUK Biobank (UKBB)Neale Lab20182173609243Adrenal Gland: p = 7.38E-4
Heart - Left Ventricle: p = 0.01
Brain - Spinal cord (cervical c-1): p = 0.01
20003_1140865588Treatment/medication code: pentasa sr 250mg m/r tabletUK Biobank (UKBB)Neale Lab20182493608923Vagina: p = 0.01
Skin - Not Sun Exposed (Suprapubic): p = 0.03
Colon - Transverse: p = 0.03
20003_1140866466Treatment/medication code: securon 40mg tabletUK Biobank (UKBB)Neale Lab20181083610333Muscle - Skeletal: p = 0.04
Pancreas: p = 0.07
Spleen: p = 0.11
20003_1140922714Treatment/medication code: dorzolamideUK Biobank (UKBB)Neale Lab20181023610393Muscle - Skeletal: p = 0.00543
Whole Blood: p = 0.00968
Esophagus - Gastroesophageal Junction: p = 0.04
20003_1140865336Treatment/medication code: spasmonal 60mg capsuleUK Biobank (UKBB)Neale Lab20182633608783Brain - Spinal cord (cervical c-1): p = 0.00135
Brain - Caudate (basal ganglia): p = 0.00255
Brain - Cerebellar Hemisphere: p = 0.00255
20003_1140861120Treatment/medication code: coracten sr 10mg m/r capsuleUK Biobank (UKBB)Neale Lab20183163608253Brain - Caudate (basal ganglia): p = 0.04
Brain - Nucleus accumbens (basal ganglia): p = 0.04
Prostate: p = 0.04
20003_1140871168Treatment/medication code: voltarol 25mg e/c tabletUK Biobank (UKBB)Neale Lab20184063607353Whole Blood: p = 0.00566
Skin - Sun Exposed (Lower leg): p = 0.01
Brain - Nucleus accumbens (basal ganglia): p = 0.03
20003_1140879866Treatment/medication code: timololUK Biobank (UKBB)Neale Lab20182793608623Heart - Left Ventricle: p = 9.97E-4
Heart - Atrial Appendage: p = 0.01
Liver: p = 0.03
20003_1141173348Treatment/medication code: hydroxocobalaminUK Biobank (UKBB)Neale Lab20183123608293Stomach: p = 0.00255
Uterus: p = 0.00409
Liver: p = 0.02
20003_1141166086Treatment/medication code: rennie duo oral suspensionUK Biobank (UKBB)Neale Lab20181243610173Adrenal Gland: p = 0.0069
Adipose - Visceral (Omentum): p = 0.01
Breast - Mammary Tissue: p = 0.01
20003_1140867444Treatment/medication code: risperidoneUK Biobank (UKBB)Neale Lab20181973609443Breast - Mammary Tissue: p = 0.00167
Minor Salivary Gland: p = 0.01
Vagina: p = 0.03
20003_1140888556Treatment/medication code: fosinoprilUK Biobank (UKBB)Neale Lab20181863609553Colon - Sigmoid: p = 0.02
Thyroid: p = 0.02
Skin - Not Sun Exposed (Suprapubic): p = 0.02
20003_1140862148Treatment/medication code: serevent 25mcg inhalerUK Biobank (UKBB)Neale Lab20189963601453Liver: p = 0.03
Esophagus - Mucosa: p = 0.04
Artery - Tibial: p = 0.10
20003_1140872492Treatment/medication code: nicotine productUK Biobank (UKBB)Neale Lab20181443609973Vagina: p = 0.02
Whole Blood: p = 0.04
Prostate: p = 0.09
20003_1140871188Treatment/medication code: etodolacUK Biobank (UKBB)Neale Lab20182773608643Skin - Not Sun Exposed (Suprapubic): p = 5.44E-6
Skin - Sun Exposed (Lower leg): p = 5.44E-6
Adipose - Subcutaneous: p = 0.02
20003_1140872694Treatment/medication code: flucloxacillinUK Biobank (UKBB)Neale Lab20181263610153Pancreas: p = 0.01
Adipose - Subcutaneous: p = 0.01
Colon - Transverse: p = 0.03
20003_1140888758Treatment/medication code: penicillin vUK Biobank (UKBB)Neale Lab20181813609603Adrenal Gland: p = 0.00124
Esophagus - Mucosa: p = 0.0081
Colon - Sigmoid: p = 0.00912
20003_1140927730Treatment/medication code: epaderm ointmentUK Biobank (UKBB)Neale Lab20182223609193Adrenal Gland: p = 0.0071
Artery - Aorta: p = 0.00843
Artery - Coronary: p = 0.01
20003_1141150750Treatment/medication code: brimonidine tartrateUK Biobank (UKBB)Neale Lab20181033610383Brain - Amygdala: p = 1.18E-4
Brain - Anterior cingulate cortex (BA24): p = 1.18E-4
Brain - Frontal Cortex (BA9): p = 1.18E-4
20003_1140860802Treatment/medication code: coversyl 2mg tabletUK Biobank (UKBB)Neale Lab20181323610093Skin - Not Sun Exposed (Suprapubic): p = 0.00115
Skin - Sun Exposed (Lower leg): p = 0.00115
Colon - Transverse: p = 0.02
20003_1141151016Treatment/medication code: losartan potassium+hydrochlorothiazide 50mg/12.5mg tabletUK Biobank (UKBB)Neale Lab20183003608412Whole Blood: p = 0.01
Adipose - Visceral (Omentum): p = 0.02
Stomach: p = 0.07
20003_1141200708Treatment/medication code: strontium productUK Biobank (UKBB)Neale Lab20181213610203Lung: p = 0.05
Ovary: p = 0.10
Whole Blood: p = 0.13
20003_1140882728Treatment/medication code: otomize ear sprayUK Biobank (UKBB)Neale Lab20181843609573Kidney - Cortex: p = 0.00361
Nerve - Tibial: p = 0.01
Pancreas: p = 0.01
20003_1141145660Treatment/medication code: valsartanUK Biobank (UKBB)Neale Lab201817073594343Kidney - Cortex: p = 0.03
Colon - Sigmoid: p = 0.04
Adrenal Gland: p = 0.08
20003_1141167940Treatment/medication code: maxalt 5mg tabletUK Biobank (UKBB)Neale Lab20182013609402Brain - Cortex: p = 0.00901
Brain - Frontal Cortex (BA9): p = 0.02
Brain - Spinal cord (cervical c-1): p = 0.02
20003_1141168322Treatment/medication code: plavix 75mg tabletUK Biobank (UKBB)Neale Lab20181823609592Minor Salivary Gland: p = 0.00234
Stomach: p = 0.00621
Colon - Transverse: p = 0.13
20003_1140910698Treatment/medication code: oil of peppermintUK Biobank (UKBB)Neale Lab20181283610133Pituitary: p = 0.03
Ovary: p = 0.11
Thyroid: p = 0.11
20003_1140862770Treatment/medication code: zirtek 10mg tabletUK Biobank (UKBB)Neale Lab20181023610393Skin - Not Sun Exposed (Suprapubic): p = 0.01
Skin - Sun Exposed (Lower leg): p = 0.01
Nerve - Tibial: p = 0.02
20003_1140880956Treatment/medication code: fentanylUK Biobank (UKBB)Neale Lab20181063610353Brain - Nucleus accumbens (basal ganglia): p = 0.00719
Brain - Caudate (basal ganglia): p = 0.02
Brain - Putamen (basal ganglia): p = 0.02
20003_1141145638Treatment/medication code: nasobec aqueous 50micrograms nasal sprayUK Biobank (UKBB)Neale Lab20181553609862Esophagus - Mucosa: p = 0.00184
Minor Salivary Gland: p = 0.00494
Brain - Cerebellum: p = 0.01
20003_1140871692Treatment/medication code: morphineUK Biobank (UKBB)Neale Lab20182133609283Colon - Sigmoid: p = 0.00288
Esophagus - Gastroesophageal Junction: p = 0.00545
Pancreas: p = 0.00545
20003_1140870306Treatment/medication code: iron+folic acidUK Biobank (UKBB)Neale Lab20181843609573Adrenal Gland: p = 0.04
Esophagus - Mucosa: p = 0.05
Small Intestine - Terminal Ileum: p = 0.07
20003_1141180314Treatment/medication code: ibandronic acidUK Biobank (UKBB)Neale Lab20183323608092Brain - Spinal cord (cervical c-1): p = 0.01
Brain - Substantia nigra: p = 0.01
Lung: p = 0.02
20003_1141174508Treatment/medication code: reductil 10mg capsuleUK Biobank (UKBB)Neale Lab20181163610253Esophagus - Mucosa: p = 0.00696
Vagina: p = 0.00696
Skin - Not Sun Exposed (Suprapubic): p = 0.00974
20003_1140862952Treatment/medication code: mucodyne 375mg capsuleUK Biobank (UKBB)Neale Lab20181343610072Adrenal Gland: p = 0.03
Muscle - Skeletal: p = 0.04
Vagina: p = 0.05
20003_1141191748Treatment/medication code: respiratory mometasoneUK Biobank (UKBB)Neale Lab20182163609252Brain - Caudate (basal ganglia): p = 0.00603
Brain - Substantia nigra: p = 0.00603
Esophagus - Mucosa: p = 0.01
20003_1140871666Treatment/medication code: piroxicamUK Biobank (UKBB)Neale Lab20181393610023Whole Blood: p = 5.41E-4
Heart - Left Ventricle: p = 0.01
Small Intestine - Terminal Ileum: p = 0.02
20003_1141162764Treatment/medication code: tolterodine l-tartrateUK Biobank (UKBB)Neale Lab20187203604212Minor Salivary Gland: p = 0.01
Breast - Mammary Tissue: p = 0.02
Thyroid: p = 0.04
20003_1140865670Treatment/medication code: salazopyrin 500mg tabletUK Biobank (UKBB)Neale Lab20182333609083Lung: p = 0.00255
Small Intestine - Terminal Ileum: p = 0.02
Colon - Transverse: p = 0.02
20003_1140869848Treatment/medication code: methotrexateUK Biobank (UKBB)Neale Lab201819183592235Spleen: p = 1.34E-9
Lung: p = 5.57E-7
Whole Blood: p = 3.62E-4
20003_1141189094Treatment/medication code: avandamet 1mg / 500mg tabletUK Biobank (UKBB)Neale Lab20181393610023Spleen: p = 0.00398
Artery - Aorta: p = 0.00567
Artery - Coronary: p = 0.00707
20003_1141199858Treatment/medication code: cardioplen xl 5mg m/r tabletUK Biobank (UKBB)Neale Lab20182133609283Adipose - Subcutaneous: p = 8.47E-4
Spleen: p = 0.00696
Colon - Sigmoid: p = 0.01
20003_1140862144Treatment/medication code: salmeterolUK Biobank (UKBB)Neale Lab20189793601623Lung: p = 2.83E-4
Prostate: p = 0.02
Esophagus - Gastroesophageal Junction: p = 0.02
20003_1140871052Treatment/medication code: calcium carbonate+cholecalciferol 1.25g/5micrograms tabletUK Biobank (UKBB)Neale Lab20181523609893Liver: p = 0.01
Spleen: p = 0.04
Artery - Tibial: p = 0.07
20003_1140867818Treatment/medication code: nortriptylineUK Biobank (UKBB)Neale Lab20182243609173Adrenal Gland: p = 8.75E-4
Stomach: p = 0.00232
Colon - Transverse: p = 0.03
20003_1141179974Treatment/medication code: cozaar 25mg tabletUK Biobank (UKBB)Neale Lab20184143607272Artery - Aorta: p = 0.00982
Esophagus - Gastroesophageal Junction: p = 0.01
Artery - Coronary: p = 0.02
20003_1140867998Treatment/medication code: motilium 10mg tabletUK Biobank (UKBB)Neale Lab20181263610152Colon - Sigmoid: p = 0.0034
Skin - Sun Exposed (Lower leg): p = 0.04
Prostate: p = 0.08
20003_1140863302Treatment/medication code: lorazepamUK Biobank (UKBB)Neale Lab20181383610033Brain - Cortex: p = 0.02
Brain - Hippocampus: p = 0.02
Artery - Aorta: p = 0.02
20003_1141157252Treatment/medication code: glyceryl trinitrate productUK Biobank (UKBB)Neale Lab20183383608033Vagina: p = 2.98E-5
Small Intestine - Terminal Ileum: p = 0.00964
Esophagus - Gastroesophageal Junction: p = 0.02
20003_1141164276Treatment/medication code: nebivololUK Biobank (UKBB)Neale Lab20183003608413Uterus: p = 0.00115
Artery - Tibial: p = 0.00502
Colon - Sigmoid: p = 0.00623
20003_1140865010Treatment/medication code: viscotears liquid eye gelUK Biobank (UKBB)Neale Lab20188413603003Vagina: p = 0.02
Colon - Sigmoid: p = 0.04
Ovary: p = 0.04
20003_1141172838Treatment/medication code: depakote 250mg e/c tabletUK Biobank (UKBB)Neale Lab20181083610333Prostate: p = 0.01
Spleen: p = 0.01
Small Intestine - Terminal Ileum: p = 0.02
20003_1141188594Treatment/medication code: humira 40mg injection solution 0.8ml prefilled syringeUK Biobank (UKBB)Neale Lab20181043610373Esophagus - Mucosa: p = 0.01
Prostate: p = 0.07
Vagina: p = 0.07
20003_1141164086Treatment/medication code: salmeterol+fluticasone propionateUK Biobank (UKBB)Neale Lab20186563604853Minor Salivary Gland: p = 0.00216
Brain - Nucleus accumbens (basal ganglia): p = 0.07
Stomach: p = 0.07
20003_1140879762Treatment/medication code: celiprololUK Biobank (UKBB)Neale Lab20181013610402Liver: p = 0.01
Esophagus - Mucosa: p = 0.02
Thyroid: p = 0.02
20003_1141180662Treatment/medication code: zirtek allergy 10mg tabletUK Biobank (UKBB)Neale Lab20181103610312Esophagus - Gastroesophageal Junction: p = 0.00523
Skin - Not Sun Exposed (Suprapubic): p = 0.00523
Skin - Sun Exposed (Lower leg): p = 0.01
20003_1140879630Treatment/medication code: imipramineUK Biobank (UKBB)Neale Lab20182023609393Artery - Coronary: p = 1.26E-4
Lung: p = 2.28E-4
Artery - Aorta: p = 0.00822
20003_1141157494Treatment/medication code: ispaghula husk productUK Biobank (UKBB)Neale Lab20181263610152Adrenal Gland: p = 0.03
Heart - Atrial Appendage: p = 0.04
Spleen: p = 0.10
20003_1140866116Treatment/medication code: frusemideUK Biobank (UKBB)Neale Lab20186243605173Adipose - Visceral (Omentum): p = 0.00543
Esophagus - Mucosa: p = 0.00725
Prostate: p = 0.01
20003_1140864070Treatment/medication code: kapake tabletUK Biobank (UKBB)Neale Lab20181043610373Colon - Transverse: p = 1.42E-5
Brain - Cortex: p = 5.28E-4
Brain - Anterior cingulate cortex (BA24): p = 0.00242
20003_1140871336Treatment/medication code: indomethacinUK Biobank (UKBB)Neale Lab20182413609003Lung: p = 2.38E-4
Spleen: p = 0.00929
Whole Blood: p = 0.05
20003_1140882272Treatment/medication code: oramorph 10mg/5ml oral solutionUK Biobank (UKBB)Neale Lab20181143610273Brain - Amygdala: p = 0.00527
Kidney - Cortex: p = 0.00527
Brain - Cerebellum: p = 0.00824
20003_1140866236Treatment/medication code: spironolactoneUK Biobank (UKBB)Neale Lab20186623604793Brain - Anterior cingulate cortex (BA24): p = 0.02
Brain - Frontal Cortex (BA9): p = 0.04
Brain - Hippocampus: p = 0.04
20003_1140927320Treatment/medication code: dermol 500 lotionUK Biobank (UKBB)Neale Lab20181163610253Esophagus - Gastroesophageal Junction: p = 0.08
Nerve - Tibial: p = 0.11
Pancreas: p = 0.11
20003_1141200072Treatment/medication code: lyrica 25mg capsuleUK Biobank (UKBB)Neale Lab20181163610253Kidney - Cortex: p = 3.24E-4
Brain - Spinal cord (cervical c-1): p = 0.00974
Stomach: p = 0.01
20003_1141200768Treatment/medication code: protelos 2g sachetsUK Biobank (UKBB)Neale Lab20181043610373Colon - Transverse: p = 0.00153
Colon - Sigmoid: p = 0.00372
Brain - Amygdala: p = 0.02
20003_1140883656Treatment/medication code: hydroxyzineUK Biobank (UKBB)Neale Lab20181243610173Heart - Atrial Appendage: p = 0.03
Liver: p = 0.03
Prostate: p = 0.04
20003_1140861128Treatment/medication code: tildiem 60mg m/r tabletUK Biobank (UKBB)Neale Lab20186973604443Brain - Nucleus accumbens (basal ganglia): p = 0.02
Esophagus - Gastroesophageal Junction: p = 0.03
Esophagus - Muscularis: p = 0.03
20003_1141171336Treatment/medication code: eprosartanUK Biobank (UKBB)Neale Lab20182293609122Colon - Sigmoid: p = 0.03
Esophagus - Muscularis: p = 0.06
Whole Blood: p = 0.06
20003_1140888510Treatment/medication code: verapamilUK Biobank (UKBB)Neale Lab20186273605142Uterus: p = 0.00111
Artery - Aorta: p = 0.02
Heart - Left Ventricle: p = 0.02
20003_1140879798Treatment/medication code: terazosinUK Biobank (UKBB)Neale Lab20181273610143Colon - Transverse: p = 2.25E-5
Whole Blood: p = 1.01E-4
Esophagus - Mucosa: p = 7.19E-4
20003_1141157126Treatment/medication code: montelukast productUK Biobank (UKBB)Neale Lab20186723604693Brain - Spinal cord (cervical c-1): p = 0.00321
Lung: p = 0.00381
Brain - Hypothalamus: p = 0.02
20003_1140913292Treatment/medication code: synalar 1:10 creamUK Biobank (UKBB)Neale Lab20181013610402Artery - Tibial: p = 0.02
Nerve - Tibial: p = 0.04
Brain - Spinal cord (cervical c-1): p = 0.06
20003_1140923670Treatment/medication code: gtn - glyceryl trinitrateUK Biobank (UKBB)Neale Lab20186213605202Esophagus - Mucosa: p = 0.00917
Pituitary: p = 0.01
Adipose - Visceral (Omentum): p = 0.02
20003_1140884696Treatment/medication code: clobetasoneUK Biobank (UKBB)Neale Lab20181163610253Small Intestine - Terminal Ileum: p = 0.00588
Brain - Anterior cingulate cortex (BA24): p = 0.01
Brain - Cortex: p = 0.01
20003_1141151284Treatment/medication code: naratriptanUK Biobank (UKBB)Neale Lab20182743608673Liver: p = 7.23E-4
Small Intestine - Terminal Ileum: p = 0.00119
Uterus: p = 0.01
20003_1140879818Treatment/medication code: metoprololUK Biobank (UKBB)Neale Lab20186873604543Spleen: p = 0.00193
Brain - Spinal cord (cervical c-1): p = 0.01
Brain - Substantia nigra: p = 0.01
20003_1141157132Treatment/medication code: singulair 10mg tabletUK Biobank (UKBB)Neale Lab20182763608653Pancreas: p = 0.01
Liver: p = 0.02
Esophagus - Gastroesophageal Junction: p = 0.04
20003_1140873476Treatment/medication code: tetralysal 300 capsuleUK Biobank (UKBB)Neale Lab20181463609953Lung: p = 2.29E-4
Uterus: p = 0.01
Artery - Aorta: p = 0.02
20003_1140916980Treatment/medication code: zantac 75 tabletUK Biobank (UKBB)Neale Lab20182013609403Skin - Not Sun Exposed (Suprapubic): p = 0.04
Skin - Sun Exposed (Lower leg): p = 0.04
Esophagus - Mucosa: p = 0.08
20003_1140868426Treatment/medication code: triamcinoloneUK Biobank (UKBB)Neale Lab20181453609963Esophagus - Muscularis: p = 0.00543
Esophagus - Gastroesophageal Junction: p = 0.00723
Uterus: p = 0.01
20003_1140862060Treatment/medication code: ventolin 2mg tabletUK Biobank (UKBB)Neale Lab20181463609953Colon - Sigmoid: p = 4.41E-4
Small Intestine - Terminal Ileum: p = 0.00685
Esophagus - Gastroesophageal Junction: p = 0.0081
20003_1140881474Treatment/medication code: normacol granulesUK Biobank (UKBB)Neale Lab20181653609763Lung: p = 0.003
Thyroid: p = 0.01
Artery - Tibial: p = 0.04
20003_1140861202Treatment/medication code: istin 5mg tabletUK Biobank (UKBB)Neale Lab20181203610213Brain - Cerebellar Hemisphere: p = 0.00182
Brain - Cerebellum: p = 0.00182
Nerve - Tibial: p = 0.00414
20003_1140860904Treatment/medication code: trandolaprilUK Biobank (UKBB)Neale Lab20182143609272Skin - Sun Exposed (Lower leg): p = 8.66E-4
Skin - Not Sun Exposed (Suprapubic): p = 0.00377
Brain - Cortex: p = 0.02
20003_1140871112Treatment/medication code: vitamin e productUK Biobank (UKBB)Neale Lab201813643597772Kidney - Cortex: p = 0.00688
Uterus: p = 0.00688
Nerve - Tibial: p = 0.00713
20003_1140883968Treatment/medication code: carmelloseUK Biobank (UKBB)Neale Lab20181563609852Brain - Hypothalamus: p = 0.01
Skin - Not Sun Exposed (Suprapubic): p = 0.01
Spleen: p = 0.02
20003_1140878186Treatment/medication code: liquifilm tears 1.4% eye dropsUK Biobank (UKBB)Neale Lab20181523609892Adrenal Gland: p = 0.05
Vagina: p = 0.06
Spleen: p = 0.06
20003_1140852756Treatment/medication code: vitamin aUK Biobank (UKBB)Neale Lab20181373610042Nerve - Tibial: p = 0.02
Minor Salivary Gland: p = 0.02
Pituitary: p = 0.02
20003_1140909482Treatment/medication code: opticrom allergy eye dropsUK Biobank (UKBB)Neale Lab20182383609032Lung: p = 7.65E-5
Brain - Cortex: p = 0.00765
Brain - Frontal Cortex (BA9): p = 0.04
20003_1140860954Treatment/medication code: isosorbide mononitrateUK Biobank (UKBB)Neale Lab201811893599523Heart - Atrial Appendage: p = 0.00328
Heart - Left Ventricle: p = 0.0081
Brain - Cortex: p = 0.01
20003_1140888390Treatment/medication code: ferrous salt productUK Biobank (UKBB)Neale Lab20181253610163Whole Blood: p = 0.0021
Minor Salivary Gland: p = 0.00536
Prostate: p = 0.00536
20003_1141168122Treatment/medication code: solpadol capsuleUK Biobank (UKBB)Neale Lab20182133609283Thyroid: p = 0.00407
Skin - Not Sun Exposed (Suprapubic): p = 0.00669
Lung: p = 0.02
20003_1141180140Treatment/medication code: etoricoxibUK Biobank (UKBB)Neale Lab20183223608193Nerve - Tibial: p = 0.01
Vagina: p = 0.02
Brain - Substantia nigra: p = 0.02
20003_1141167708Treatment/medication code: beclomist 50micrograms nasal sprayUK Biobank (UKBB)Neale Lab20181213610202Spleen: p = 0.00824
Kidney - Cortex: p = 0.00968
Adipose - Subcutaneous: p = 0.08
20003_1140878324Treatment/medication code: oilatum creamUK Biobank (UKBB)Neale Lab20181563609853Spleen: p = 3.56E-5
Minor Salivary Gland: p = 0.00675
Small Intestine - Terminal Ileum: p = 0.00988
20003_1140865016Treatment/medication code: zolpidemUK Biobank (UKBB)Neale Lab20182683608733Kidney - Cortex: p = 0.02
Vagina: p = 0.03
Breast - Mammary Tissue: p = 0.04
20003_1140876146Treatment/medication code: rhinocort 50micrograms nasal sprayUK Biobank (UKBB)Neale Lab20181603609813Skin - Not Sun Exposed (Suprapubic): p = 2.7E-5
Skin - Sun Exposed (Lower leg): p = 2.7E-5
Breast - Mammary Tissue: p = 2.96E-4
20003_1140909872Treatment/medication code: vitamin b1 preparationUK Biobank (UKBB)Neale Lab20181563609853Kidney - Cortex: p = 0.01
Skin - Not Sun Exposed (Suprapubic): p = 0.02
Skin - Sun Exposed (Lower leg): p = 0.02
20003_1140923484Treatment/medication code: topiramateUK Biobank (UKBB)Neale Lab20182093609322Whole Blood: p = 0.00559
Vagina: p = 0.01
Brain - Anterior cingulate cortex (BA24): p = 0.01
20003_1140864950Treatment/medication code: bisoprolol fumarate+hydrochlorothiazide 10mg/6.25mg tabletUK Biobank (UKBB)Neale Lab20182343609072Breast - Mammary Tissue: p = 0.00576
Adipose - Subcutaneous: p = 0.02
Brain - Frontal Cortex (BA9): p = 0.02
20003_1141195044Treatment/medication code: hydroxycarbamideUK Biobank (UKBB)Neale Lab20181613609803Uterus: p = 0.02
Esophagus - Mucosa: p = 0.04
Nerve - Tibial: p = 0.07
20003_1140864952Treatment/medication code: lisinopril+hydrochlorothiazide 10mg/12.5mg tabletUK Biobank (UKBB)Neale Lab20181253610163Skin - Sun Exposed (Lower leg): p = 5.23E-4
Adipose - Visceral (Omentum): p = 0.00145
Brain - Amygdala: p = 0.00299
20003_1141173328Treatment/medication code: ursodeoxycholic acidUK Biobank (UKBB)Neale Lab20181283610133Artery - Aorta: p = 0.01
Brain - Anterior cingulate cortex (BA24): p = 0.01
Colon - Transverse: p = 0.01
20003_1140868064Treatment/medication code: serc-8 tabletUK Biobank (UKBB)Neale Lab20181103610313Esophagus - Mucosa: p = 3.0E-4
Vagina: p = 0.01
Adipose - Visceral (Omentum): p = 0.08
20003_1140882394Treatment/medication code: paracetamol + codeineUK Biobank (UKBB)Neale Lab20183083608333Brain - Hypothalamus: p = 0.0069
Brain - Amygdala: p = 0.02
Artery - Coronary: p = 0.03
20003_1141157178Treatment/medication code: senna productUK Biobank (UKBB)Neale Lab20181343610073Pituitary: p = 0.00265
Thyroid: p = 0.00308
Esophagus - Mucosa: p = 0.00593
20003_1140911638Treatment/medication code: kelp+garlic productUK Biobank (UKBB)Neale Lab20182003609413Whole Blood: p = 0.00732
Brain - Anterior cingulate cortex (BA24): p = 0.05
Colon - Sigmoid: p = 0.06
20003_1140910498Treatment/medication code: flu - influenza vaccineUK Biobank (UKBB)Neale Lab20181423609993Brain - Anterior cingulate cortex (BA24): p = 0.01
Brain - Cortex: p = 0.01
Brain - Frontal Cortex (BA9): p = 0.01
20003_1140870488Treatment/medication code: forceval capsuleUK Biobank (UKBB)Neale Lab20181043610373Stomach: p = 0.00534
Kidney - Cortex: p = 0.01
Skin - Not Sun Exposed (Suprapubic): p = 0.03
20003_1140865872Treatment/medication code: magnesium citrateUK Biobank (UKBB)Neale Lab20181373610043Nerve - Tibial: p = 0.01
Artery - Coronary: p = 0.04
Stomach: p = 0.06
20003_1141171940Treatment/medication code: keppra 250mg tabletUK Biobank (UKBB)Neale Lab20181173610243Liver: p = 4.34E-4
Skin - Sun Exposed (Lower leg): p = 0.01
Pituitary: p = 0.02
20003_1140910766Treatment/medication code: nicorandilUK Biobank (UKBB)Neale Lab201811523599893Thyroid: p = 0.0077
Artery - Coronary: p = 0.01
Adrenal Gland: p = 0.02
20003_1141168752Treatment/medication code: peptac liquidUK Biobank (UKBB)Neale Lab20183523607893Colon - Transverse: p = 7.0E-5
Esophagus - Muscularis: p = 0.00199
Artery - Tibial: p = 0.00727
20003_1140879792Treatment/medication code: terbutalineUK Biobank (UKBB)Neale Lab20185723605692Liver: p = 0.09
Artery - Aorta: p = 0.14
Ovary: p = 0.15
20003_1141175684Treatment/medication code: risedronate sodiumUK Biobank (UKBB)Neale Lab20187183604233Brain - Substantia nigra: p = 0.00586
Brain - Frontal Cortex (BA9): p = 0.01
Brain - Hypothalamus: p = 0.01
20003_1140865752Treatment/medication code: ispaghula huskUK Biobank (UKBB)Neale Lab20183273608143Skin - Not Sun Exposed (Suprapubic): p = 0.00843
Skin - Sun Exposed (Lower leg): p = 0.00843
Whole Blood: p = 0.01
20003_1140871196Treatment/medication code: lodine 200mg tabletUK Biobank (UKBB)Neale Lab20181643609772Pancreas: p = 0.00691
Small Intestine - Terminal Ileum: p = 0.02
Colon - Transverse: p = 0.05
20003_1140861778Treatment/medication code: dipyridamoleUK Biobank (UKBB)Neale Lab20186663604753Pancreas: p = 0.03
Lung: p = 0.04
Pituitary: p = 0.04
20003_1140851812Treatment/medication code: gtn 400micrograms sprayUK Biobank (UKBB)Neale Lab20188493602923Heart - Atrial Appendage: p = 6.26E-4
Muscle - Skeletal: p = 6.26E-4
Vagina: p = 0.00321
20003_1140872338Treatment/medication code: madopar 62.5 capsuleUK Biobank (UKBB)Neale Lab20181123610293Brain - Cerebellum: p = 7.26E-4
Brain - Substantia nigra: p = 0.00538
Brain - Caudate (basal ganglia): p = 0.01
20003_1140868172Treatment/medication code: stemetil 5mg tabletUK Biobank (UKBB)Neale Lab20182313609103Prostate: p = 8.22E-4
Colon - Sigmoid: p = 0.02
Artery - Aorta: p = 0.02
20003_1141157402Treatment/medication code: prednisolone productUK Biobank (UKBB)Neale Lab20181393610023Minor Salivary Gland: p = 0.00639
Liver: p = 0.03
Pancreas: p = 0.04
20003_1140868080Treatment/medication code: cyclizineUK Biobank (UKBB)Neale Lab20181363610052Uterus: p = 0.01
Kidney - Cortex: p = 0.02
Colon - Sigmoid: p = 0.04
20003_1140888366Treatment/medication code: thiamine preparationUK Biobank (UKBB)Neale Lab20185493605923Esophagus - Gastroesophageal Junction: p = 2.08E-7
Esophagus - Muscularis: p = 2.37E-6
Artery - Tibial: p = 2.69E-6
20003_1141179764Treatment/medication code: tenofovirUK Biobank (UKBB)Neale Lab20181043610373Esophagus - Gastroesophageal Junction: p = 0.01
Esophagus - Muscularis: p = 0.03
Lung: p = 0.05
20003_1140881320Treatment/medication code: magnesium carbonateUK Biobank (UKBB)Neale Lab20181293610123Brain - Caudate (basal ganglia): p = 4.93E-4
Brain - Putamen (basal ganglia): p = 0.00143
Brain - Amygdala: p = 0.00385
20003_1140868364Treatment/medication code: prednisoneUK Biobank (UKBB)Neale Lab20182283609133Ovary: p = 9.95E-4
Pituitary: p = 0.00519
Whole Blood: p = 0.00592
20003_1140879392Treatment/medication code: manevac granulesUK Biobank (UKBB)Neale Lab20181313610103Esophagus - Muscularis: p = 0.00377
Esophagus - Gastroesophageal Junction: p = 0.00592
Colon - Sigmoid: p = 0.00911
20003_1141181868Treatment/medication code: omacor 1g capsuleUK Biobank (UKBB)Neale Lab20184603606813Whole Blood: p = 0.01
Adipose - Subcutaneous: p = 0.01
Liver: p = 0.01
20003_1140862526Treatment/medication code: sodium cromoglycateUK Biobank (UKBB)Neale Lab20181143610273Brain - Nucleus accumbens (basal ganglia): p = 0.07
Ovary: p = 0.07
Whole Blood: p = 0.07
20003_1140871506Treatment/medication code: ketoprofenUK Biobank (UKBB)Neale Lab20181223610192Small Intestine - Terminal Ileum: p = 0.04
Minor Salivary Gland: p = 0.06
Ovary: p = 0.06
20003_1140909874Treatment/medication code: vitamin b6 preparationUK Biobank (UKBB)Neale Lab20184403607013Whole Blood: p = 0.04
Nerve - Tibial: p = 0.09
Testis: p = 0.10
20003_1140928284Treatment/medication code: moxonidineUK Biobank (UKBB)Neale Lab20183113608302Pancreas: p = 0.01
Whole Blood: p = 0.03
Adipose - Subcutaneous: p = 0.05
20003_1141190160Treatment/medication code: vascalpha 5mg m/r tabletUK Biobank (UKBB)Neale Lab20181213610203Brain - Hypothalamus: p = 8.66E-4
Ovary: p = 0.00592
Colon - Transverse: p = 0.01
20003_1140861936Treatment/medication code: questran 4g/sachet powderUK Biobank (UKBB)Neale Lab20181173610242Brain - Anterior cingulate cortex (BA24): p = 0.00155
Brain - Hippocampus: p = 0.00414
Brain - Amygdala: p = 0.01
20003_1140925978Treatment/medication code: mycophenolateUK Biobank (UKBB)Neale Lab20181613609802Artery - Coronary: p = 0.02
Skin - Not Sun Exposed (Suprapubic): p = 0.04
Thyroid: p = 0.04
20003_1141195224Treatment/medication code: formoterolUK Biobank (UKBB)Neale Lab20181063610353Artery - Aorta: p = 0.01
Kidney - Cortex: p = 0.02
Adipose - Subcutaneous: p = 0.03
20003_1140875632Treatment/medication code: movelat gelUK Biobank (UKBB)Neale Lab20181303610113Esophagus - Mucosa: p = 1.82E-4
Small Intestine - Terminal Ileum: p = 0.02
Colon - Transverse: p = 0.02
20003_1140871688Treatment/medication code: solpadol capletUK Biobank (UKBB)Neale Lab20183003608413Esophagus - Mucosa: p = 5.17E-4
Vagina: p = 0.00229
Adrenal Gland: p = 0.02
20003_1141172698Treatment/medication code: monomax xl 60mg m/r tabletUK Biobank (UKBB)Neale Lab20181103610313Kidney - Cortex: p = 0.03
Whole Blood: p = 0.04
Heart - Left Ventricle: p = 0.06
20003_1140871680Treatment/medication code: tylex capsuleUK Biobank (UKBB)Neale Lab20181753609663Adipose - Visceral (Omentum): p = 0.02
Pancreas: p = 0.02
Spleen: p = 0.03
20003_1140865414Treatment/medication code: peppermint oil productUK Biobank (UKBB)Neale Lab20181893609523Nerve - Tibial: p = 8.53E-4
Brain - Spinal cord (cervical c-1): p = 0.00562
Brain - Hippocampus: p = 0.02
20003_1141177600Treatment/medication code: rosiglitazoneUK Biobank (UKBB)Neale Lab20185313606103Spleen: p = 0.00394
Artery - Tibial: p = 0.00855
Lung: p = 0.009
20003_1140856342Treatment/medication code: syndol tabletUK Biobank (UKBB)Neale Lab20182893608523Esophagus - Muscularis: p = 0.00312
Esophagus - Gastroesophageal Junction: p = 0.0074
Prostate: p = 0.0074
20003_1140865668Treatment/medication code: sulphasalazineUK Biobank (UKBB)Neale Lab20181973609443Lung: p = 9.75E-4
Stomach: p = 0.00114
Ovary: p = 0.02
20003_1141153032Treatment/medication code: zanidip 10mg tabletUK Biobank (UKBB)Neale Lab20181723609693Pancreas: p = 0.00488
Esophagus - Muscularis: p = 0.06
Heart - Atrial Appendage: p = 0.06
20003_1140865394Treatment/medication code: hyoscine butylbromideUK Biobank (UKBB)Neale Lab20181033610382Skin - Not Sun Exposed (Suprapubic): p = 0.00298
Skin - Sun Exposed (Lower leg): p = 0.00298
Vagina: p = 0.01
20003_1140888362Treatment/medication code: pyridoxine preparationUK Biobank (UKBB)Neale Lab20181183610232Colon - Sigmoid: p = 0.01
Thyroid: p = 0.01
Uterus: p = 0.02
20003_1140865000Treatment/medication code: zydol 50mg capsuleUK Biobank (UKBB)Neale Lab20181133610282Whole Blood: p = 4.04E-4
Esophagus - Muscularis: p = 0.00761
Colon - Sigmoid: p = 0.02
20003_1140860728Treatment/medication code: quinaprilUK Biobank (UKBB)Neale Lab20181603609813Vagina: p = 3.25E-5
Breast - Mammary Tissue: p = 0.01
Adipose - Visceral (Omentum): p = 0.02
20003_1141189090Treatment/medication code: rosiglitazone 1mg / metformin 500mg tabletUK Biobank (UKBB)Neale Lab20181523609892Artery - Aorta: p = 0.00617
Heart - Atrial Appendage: p = 0.03
Muscle - Skeletal: p = 0.06
20003_1140861780Treatment/medication code: persantin 25mg tabletUK Biobank (UKBB)Neale Lab20182153609263Heart - Atrial Appendage: p = 0.03
Adrenal Gland: p = 0.05
Vagina: p = 0.05
20003_1141164872Treatment/medication code: sinemet-62.5 tabletUK Biobank (UKBB)Neale Lab20181213610203Adipose - Visceral (Omentum): p = 0.00222
Esophagus - Gastroesophageal Junction: p = 0.01
Adipose - Subcutaneous: p = 0.02
20003_1141190960Treatment/medication code: tramacet 325mg/37.5mg tabletUK Biobank (UKBB)Neale Lab20181243610173Artery - Coronary: p = 0.02
Prostate: p = 0.02
Artery - Aorta: p = 0.02
20003_1140911642Treatment/medication code: tacrolimusUK Biobank (UKBB)Neale Lab20181803609612Thyroid: p = 0.04
Artery - Tibial: p = 0.07
Lung: p = 0.07
20003_1141157264Treatment/medication code: salmeterol productUK Biobank (UKBB)Neale Lab20182243609172Skin - Not Sun Exposed (Suprapubic): p = 0.00151
Skin - Sun Exposed (Lower leg): p = 0.00151
Breast - Mammary Tissue: p = 0.00904
20003_1140888762Treatment/medication code: ismn - isosorbide mononitrateUK Biobank (UKBB)Neale Lab20182053609363Brain - Frontal Cortex (BA9): p = 0.01
Small Intestine - Terminal Ileum: p = 0.03
Colon - Transverse: p = 0.03
20003_1141145630Treatment/medication code: nitromin 400micrograms cfc-free sprayUK Biobank (UKBB)Neale Lab20181053610362Colon - Transverse: p = 0.00671
Kidney - Cortex: p = 0.01
Muscle - Skeletal: p = 0.01
20003_1141171646Treatment/medication code: pioglitazoneUK Biobank (UKBB)Neale Lab20187443603973Skin - Sun Exposed (Lower leg): p = 0.01
Skin - Not Sun Exposed (Suprapubic): p = 0.02
Esophagus - Mucosa: p = 0.03
20003_1140862438Treatment/medication code: uniphyllin continus 200mg m/r tabletUK Biobank (UKBB)Neale Lab20181863609553Adrenal Gland: p = 0.00543
Kidney - Cortex: p = 0.01
Brain - Spinal cord (cervical c-1): p = 0.03
20003_1141171038Treatment/medication code: oxycodone hydrochlorideUK Biobank (UKBB)Neale Lab20181023610393Skin - Sun Exposed (Lower leg): p = 0.0045
Artery - Coronary: p = 0.00914
Heart - Atrial Appendage: p = 0.04
20003_1140911698Treatment/medication code: slozem 120mg m/r capsuleUK Biobank (UKBB)Neale Lab20181453609963Colon - Sigmoid: p = 0.00594
Skin - Sun Exposed (Lower leg): p = 0.00843
Esophagus - Muscularis: p = 0.02
20003_1140878172Treatment/medication code: tears naturale eye dropsUK Biobank (UKBB)Neale Lab20181143610273Artery - Tibial: p = 0.01
Artery - Coronary: p = 0.03
Adrenal Gland: p = 0.04
20003_1140860976Treatment/medication code: imdur 60mg duruleUK Biobank (UKBB)Neale Lab20181493609922Whole Blood: p = 0.00765
Esophagus - Mucosa: p = 0.04
Colon - Transverse: p = 0.05
20003_1141168108Treatment/medication code: isotard 25xl m/r tabletUK Biobank (UKBB)Neale Lab20181563609853Small Intestine - Terminal Ileum: p = 0.00161
Kidney - Cortex: p = 0.00901
Artery - Tibial: p = 0.04
20003_1140860840Treatment/medication code: nitrolingual 400micrograms sprayUK Biobank (UKBB)Neale Lab20183803607613Heart - Atrial Appendage: p = 0.01
Heart - Left Ventricle: p = 0.04
Vagina: p = 0.04
20003_1140910512Treatment/medication code: ismo - isosorbide mononitrateUK Biobank (UKBB)Neale Lab20181263610152Heart - Left Ventricle: p = 0.05
Ovary: p = 0.05
Pituitary: p = 0.05
20024_3211Job code - deduced: NursesUK Biobank (UKBB)Neale Lab201857293353Muscle - Skeletal: p = 0.01
Artery - Tibial: p = 0.06
Colon - Sigmoid: p = 0.06
20024_1121Job code - deduced: Production, works and maintenance managersUK Biobank (UKBB)Neale Lab201825196562Skin - Not Sun Exposed (Suprapubic): p = 0.00116
Skin - Sun Exposed (Lower leg): p = 0.00509
Brain - Frontal Cortex (BA9): p = 0.03
20024_1132Job code - deduced: Marketing and sales managersUK Biobank (UKBB)Neale Lab201820397043Spleen: p = 2.36E-4
Brain - Cortex: p = 0.00844
Skin - Not Sun Exposed (Suprapubic): p = 0.00974
20024_1136Job code - deduced: Information and communication technology managersUK Biobank (UKBB)Neale Lab201811597923Brain - Amygdala: p = 0.00126
Brain - Frontal Cortex (BA9): p = 0.00126
Brain - Hippocampus: p = 0.00126
20024_1163Job code - deduced: Retail and wholesale managersUK Biobank (UKBB)Neale Lab201823996683Muscle - Skeletal: p = 0.00707
Artery - Coronary: p = 0.02
Prostate: p = 0.02
20024_1239Job code - deduced: Managers and proprietors in other services n.e.c.UK Biobank (UKBB)Neale Lab201812897793Pancreas: p = 0.00874
Artery - Tibial: p = 0.02
Whole Blood: p = 0.02
20024_2211Job code - deduced: Medical practitionersUK Biobank (UKBB)Neale Lab201811797903Esophagus - Gastroesophageal Junction: p = 0.03
Heart - Atrial Appendage: p = 0.03
Spleen: p = 0.04
20024_2315Job code - deduced: Primary and nursery education teaching professionalsUK Biobank (UKBB)Neale Lab201820597022Esophagus - Mucosa: p = 0.00135
Brain - Spinal cord (cervical c-1): p = 0.04
Liver: p = 0.04
20024_3119Job code - deduced: Science and engineering technicians n.e.c.UK Biobank (UKBB)Neale Lab201811497933Kidney - Cortex: p = 1.82E-4
Brain - Cerebellar Hemisphere: p = 0.00103
Testis: p = 0.00153
20024_3232Job code - deduced: Housing and welfare officersUK Biobank (UKBB)Neale Lab201825496533Esophagus - Gastroesophageal Junction: p = 0.00107
Esophagus - Muscularis: p = 0.0029
Artery - Tibial: p = 0.01
20024_3563Job code - deduced: Vocational and industrial trainers and instructorsUK Biobank (UKBB)Neale Lab201813097772Artery - Tibial: p = 0.01
Liver: p = 0.04
Colon - Transverse: p = 0.06
20024_4112Job code - deduced: Civil Service administrative officers and assistantsUK Biobank (UKBB)Neale Lab201824096673Nerve - Tibial: p = 0.00215
Heart - Left Ventricle: p = 0.02
Spleen: p = 0.05
20024_4113Job code - deduced: Local government clerical officers and assistantsUK Biobank (UKBB)Neale Lab201811697912Kidney - Cortex: p = 0.01
Whole Blood: p = 0.02
Colon - Sigmoid: p = 0.04
20024_4122Job code - deduced: Accounts and wages clerks, book-keepers, other financial clerksUK Biobank (UKBB)Neale Lab201812597823Esophagus - Mucosa: p = 0.00181
Ovary: p = 0.00592
Liver: p = 0.01
20024_4150Job code - deduced: General office assistants/clerksUK Biobank (UKBB)Neale Lab201831295953Pituitary: p = 0.04
Skin - Not Sun Exposed (Suprapubic): p = 0.04
Skin - Sun Exposed (Lower leg): p = 0.04
20024_6115Job code - deduced: Care assistants and home carersUK Biobank (UKBB)Neale Lab201827696312Colon - Sigmoid: p = 0.01
Adipose - Subcutaneous: p = 0.02
Adipose - Visceral (Omentum): p = 0.02
20024_7111Job code - deduced: Sales and retail assistantsUK Biobank (UKBB)Neale Lab201810398043Spleen: p = 0.009
Ovary: p = 0.03
Artery - Tibial: p = 0.06
20079_6Day-of-week questionnaire completion requested: SaturdayUK Biobank (UKBB)Neale Lab20188844425832Breast - Mammary Tissue: p = 0.00907
Minor Salivary Gland: p = 0.00907
Whole Blood: p = 0.02
20079_1Day-of-week questionnaire completion requested: MondayUK Biobank (UKBB)Neale Lab20188041433862Esophagus - Muscularis: p = 0.00196
Stomach: p = 0.01
Esophagus - Gastroesophageal Junction: p = 0.03
20079_2Day-of-week questionnaire completion requested: TuesdayUK Biobank (UKBB)Neale Lab20188286431413Brain - Frontal Cortex (BA9): p = 0.0069
Adipose - Subcutaneous: p = 0.01
Whole Blood: p = 0.02
20079_3Day-of-week questionnaire completion requested: WednesdayUK Biobank (UKBB)Neale Lab20188603428243Small Intestine - Terminal Ileum: p = 0.02
Adipose - Visceral (Omentum): p = 0.02
Lung: p = 0.02
20079_4Day-of-week questionnaire completion requested