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Organism: Hsapiens, Id Type: entrezgene, Ref Set: entrezgene, Significance Level: Top10, Statistics Test: Hypergeometric, MTC: BH, Minimum: 2 The results for each enriched gene set are listed in this table. For each gene set, the first row lists the gene set name, and corresponding Gene Set ID. The second row lists number of reference genes in the category (C), number of genes in the gene set and also in the category (O), expected number in the category (E), Ratio of enrichment (R), p value from hypergeometric test (rawP), and p value adjusted by the multiple test adjustment (adjP). Finally, genes in the pathway are listed. For each gene, the table lists the user uploaded ID and value (optional), Entrez ID, Ensembl Gene Stable ID, Gene symbol, and description. Ensembl Gene Stable ID and Entrez Gene ID are linked to the Ensembl and Entrez Gene databases, respectively. | |||||
| Pathway Commons pathway----Integrin family cell surface interactions----DB_ID:1499 | |||||
| C=1378;O=114;E=10.90;R=10.46;rawP=3.92e-83;adjP=1.66e-80 | |||||
| 6347 | NA | 6347 | ENSG00000108691 | CCL2 | chemokine (C-C motif) ligand 2 |
| 959 | NA | 959 | ENSG00000102245 | CD40LG | CD40 ligand |
| 3791 | NA | 3791 | ENSG00000128052 | KDR | kinase insert domain receptor (a type III receptor tyrosine kinase) |
| 5037 | NA | 5037 | ENSG00000089220 | PEBP1 | phosphatidylethanolamine binding protein 1 |
| 1950 | NA | 1950 | ENSG00000138798 | EGF | epidermal growth factor |
| 3596 | NA | 3596 | ENSG00000169194 | IL13 | interleukin 13 |
| 6648 | NA | 6648 | ENSG00000112096 | SOD2 | superoxide dismutase 2, mitochondrial |
| 7157 | NA | 7157 | ENSG00000141510 | TP53 | tumor protein p53 |
| 331 | NA | 331 | ENSG00000101966 | XIAP | X-linked inhibitor of apoptosis |
| 4090 | NA | 4090 | ENSG00000113658 | SMAD5 | SMAD family member 5 |
| 2355 | NA | 2355 | ENSG00000075426 | FOSL2 | FOS-like antigen 2 |
| 5578 | NA | 5578 | ENSG00000154229 | PRKCA | protein kinase C, alpha |
| 3162 | NA | 3162 | ENSG00000100292 | HMOX1 | heme oxygenase (decycling) 1 |
| 5156 | NA | 5156 | ENSG00000134853 | PDGFRA | platelet-derived growth factor receptor, alpha polypeptide |
| 5566 | NA | 5566 | ENSG00000072062 | PRKACA | protein kinase, cAMP-dependent, catalytic, alpha |
| 5155 | NA | 5155 | ENSG00000100311 | PDGFB | platelet-derived growth factor beta polypeptide |
| 3371 | NA | 3371 | ENSG00000041982 | TNC | tenascin C |
| 7474 | NA | 7474 | ENSG00000114251 | WNT5A | wingless-type MMTV integration site family, member 5A |
| 2022 | NA | 2022 | ENSG00000106991 | ENG | endoglin |
| 595 | NA | 595 | ENSG00000110092 | CCND1 | cyclin D1 |
| 10746 | NA | 10746 | ENSG00000169967 | MAP3K2 | mitogen-activated protein kinase kinase kinase 2 |
| 7049 | NA | 7049 | ENSG00000069702 | TGFBR3 | transforming growth factor, beta receptor III |
| 114907 | NA | 114907 | ENSG00000156804 | FBXO32 | F-box protein 32 |
| 1499 | NA | 1499 | ENSG00000168036 | CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa |
| 1490 | NA | 1490 | ENSG00000118523 | CTGF | connective tissue growth factor |
| 1027 | NA | 1027 | ENSG00000111276 | CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) |
| 4791 | NA | 4791 | ENSG00000077150 | NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) |
| 841 | NA | 841 | ENSG00000064012 | CASP8 | caspase 8, apoptosis-related cysteine peptidase |
| 1401 | NA | 1401 | ENSG00000132693 | CRP | C-reactive protein, pentraxin-related |
| 5159 | NA | 5159 | ENSG00000113721 | PDGFRB | platelet-derived growth factor receptor, beta polypeptide |
| 718 | NA | 718 | ENSG00000125730 | C3 | complement component 3 |
| 468 | NA | 468 | ENSG00000128272 | ATF4 | activating transcription factor 4 (tax-responsive enhancer element B67) |
| 207 | NA | 207 | ENSG00000142208 | AKT1 | v-akt murine thymoma viral oncogene homolog 1 |
| 4093 | NA | 4093 | ENSG00000120693 | SMAD9 | SMAD family member 9 |
| 5468 | NA | 5468 | ENSG00000132170 | PPARG | peroxisome proliferator-activated receptor gamma |
| 842 | NA | 842 | ENSG00000132906 | CASP9 | caspase 9, apoptosis-related cysteine peptidase |
| 4035 | NA | 4035 | ENSG00000123384 | LRP1 | low density lipoprotein receptor-related protein 1 |
| 4312 | NA | 4312 | ENSG00000196611 | MMP1 | matrix metallopeptidase 1 (interstitial collagenase) |
| 4773 | NA | 4773 | ENSG00000101096 | NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 |
| 857 | NA | 857 | ENSG00000105974 | CAV1 | caveolin 1, caveolae protein, 22kDa |
| 7422 | NA | 7422 | ENSG00000112715 | VEGFA | vascular endothelial growth factor A |
| 4088 | NA | 4088 | ENSG00000166949 | SMAD3 | SMAD family member 3 |
| 1907 | NA | 1907 | ENSG00000127129 | EDN2 | endothelin 2 |
| 5743 | NA | 5743 | ENSG00000073756 | PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
| 4087 | NA | 4087 | ENSG00000175387 | SMAD2 | SMAD family member 2 |
| 4314 | NA | 4314 | ENSG00000149968 | MMP3 | matrix metallopeptidase 3 (stromelysin 1, progelatinase) |
| 6772 | NA | 6772 | ENSG00000115415 | STAT1 | signal transducer and activator of transcription 1, 91kDa |
| 3065 | NA | 3065 | ENSG00000116478 | HDAC1 | histone deacetylase 1 |
| 3082 | NA | 3082 | ENSG00000019991 | HGF | hepatocyte growth factor (hepapoietin A; scatter factor) |
| 22926 | NA | 22926 | ENSG00000118217 | ATF6 | activating transcription factor 6 |
| 7412 | NA | 7412 | ENSG00000162692 | VCAM1 | vascular cell adhesion molecule 1 |
| 5054 | NA | 5054 | ENSG00000106366 | SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 |
| 657 | NA | 657 | ENSG00000107779 | BMPR1A | bone morphogenetic protein receptor, type IA |
| 7054 | NA | 7054 | ENSG00000180176 | TH | tyrosine hydroxylase |
| 6093 | NA | 6093 | ENSG00000067900 | ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 |
| 4086 | NA | 4086 | ENSG00000170365 | SMAD1 | SMAD family member 1 |
| 10891 | NA | 10891 | ENSG00000109819 | PPARGC1A | peroxisome proliferator-activated receptor gamma, coactivator 1 alpha |
| 5594 | NA | 5594 | ENSG00000100030 | MAPK1 | mitogen-activated protein kinase 1 |
| 57154 | NA | 57154 | ENSG00000198742 | SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 |
| 4089 | NA | 4089 | ENSG00000141646 | SMAD4 | SMAD family member 4 |
| 3598 | NA | 3598 | ENSG00000123496 | IL13RA2 | interleukin 13 receptor, alpha 2 |
| 658 | NA | 658 | ENSG00000138696 | BMPR1B | bone morphogenetic protein receptor, type IB |
| 4318 | NA | 4318 | ENSG00000100985 | MMP9 | matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) |
| 7433 | NA | 7433 | ENSG00000114812 | VIPR1 | vasoactive intestinal peptide receptor 1 |
| 659 | NA | 659 | ENSG00000204217 | BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) |
| 2335 | NA | 2335 | ENSG00000115414 | FN1 | fibronectin 1 |
| 4092 | NA | 4092 | ENSG00000101665 | SMAD7 | SMAD family member 7 |
| 3398 | NA | 3398 | ENSG00000115738 | ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein |
| 7046 | NA | 7046 | ENSG00000106799 | TGFBR1 | transforming growth factor, beta receptor 1 |
| 9518 | NA | 9518 | ENSG00000130513 | GDF15 | growth differentiation factor 15 |
| 7048 | NA | 7048 | ENSG00000163513 | TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) |
| 4485 | NA | 4485 | ENSG00000173531 | MST1 | macrophage stimulating 1 (hepatocyte growth factor-like) |
| 6714 | NA | 6714 | ENSG00000197122 | SRC | v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) |
| 3383 | NA | 3383 | ENSG00000090339 | ICAM1 | intercellular adhesion molecule 1 |
| 7057 | NA | 7057 | ENSG00000137801 | THBS1 | thrombospondin 1 |
| 650 | NA | 650 | ENSG00000125845 | BMP2 | bone morphogenetic protein 2 |
| 3662 | NA | 3662 | ENSG00000137265 | IRF4 | interferon regulatory factor 4 |
| 6696 | NA | 6696 | ENSG00000118785 | SPP1 | secreted phosphoprotein 1 |
| 8600 | NA | 8600 | ENSG00000120659 | TNFSF11 | tumor necrosis factor (ligand) superfamily, member 11 |
| 4775 | NA | 4775 | ENSG00000072736 | NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 |
| 7076 | NA | 7076 | ENSG00000102265 | TIMP1 | TIMP metallopeptidase inhibitor 1 |
| 3480 | NA | 3480 | ENSG00000140443 | IGF1R | insulin-like growth factor 1 receptor |
| 57060 | NA | 57060 | ENSG00000090097 | PCBP4 | poly(rC) binding protein 4 |
| 4313 | NA | 4313 | ENSG00000087245 | MMP2 | matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) |
| 5592 | NA | 5592 | ENSG00000185532 | PRKG1 | protein kinase, cGMP-dependent, type I |
| 3913 | NA | 3913 | ENSG00000172037 | LAMB2 | laminin, beta 2 (laminin S) |
| 3952 | NA | 3952 | ENSG00000174697 | LEP | leptin |
| 1910 | NA | 1910 | ENSG00000136160 | EDNRB | endothelin receptor type B |
| 6387 | NA | 6387 | ENSG00000107562 | CXCL12 | chemokine (C-X-C motif) ligand 12 |
| 5292 | NA | 5292 | ENSG00000137193 | PIM1 | pim-1 oncogene |
| 6774 | NA | 6774 | ENSG00000168610 | STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) |
| 5551 | NA | 5551 | ENSG00000180644 | PRF1 | perforin 1 (pore forming protein) |
| 9475 | NA | 9475 | ENSG00000134318 | ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 |
| 1843 | NA | 1843 | ENSG00000120129 | DUSP1 | dual specificity phosphatase 1 |
| 4846 | NA | 4846 | ENSG00000164867 | NOS3 | nitric oxide synthase 3 (endothelial cell) |
| 7040 | NA | 7040 | ENSG00000105329 | TGFB1 | transforming growth factor, beta 1 |
| 7124 | NA | 7124 | ENSG00000232810 | TNF | tumor necrosis factor |
| 993 | NA | 993 | ENSG00000164045 | CDC25A | cell division cycle 25 homolog A (S. pombe) |
| 26585 | NA | 26585 | ENSG00000166923 | GREM1 | gremlin 1 |
| 387 | NA | 387 | ENSG00000067560 | RHOA | ras homolog family member A |
| 5617 | NA | 5617 | ENSG00000172179 | PRL | prolactin |
| 1906 | NA | 1906 | ENSG00000078401 | EDN1 | endothelin 1 |
| 7045 | NA | 7045 | ENSG00000120708 | TGFBI | transforming growth factor, beta-induced, 68kDa |
| 2353 | NA | 2353 | ENSG00000170345 | FOS | FBJ murine osteosarcoma viral oncogene homolog |
| 1956 | NA | 1956 | ENSG00000146648 | EGFR | epidermal growth factor receptor |
| 1051 | NA | 1051 | ENSG00000172216 | CEBPB | CCAAT/enhancer binding protein (C/EBP), beta |
| 185 | NA | 185 | ENSG00000144891 | AGTR1 | angiotensin II receptor, type 1 |
| 3091 | NA | 3091 | ENSG00000100644 | HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) |
| 3569 | NA | 3569 | ENSG00000136244 | IL6 | interleukin 6 (interferon, beta 2) |
| 961 | NA | 961 | ENSG00000196776 | CD47 | CD47 molecule |
| 3099 | NA | 3099 | ENSG00000159399 | HK2 | hexokinase 2 |
| 652 | NA | 652 | ENSG00000125378 | BMP4 | bone morphogenetic protein 4 |
| 2099 | NA | 2099 | ENSG00000091831 | ESR1 | estrogen receptor 1 |
| 4843 | NA | 4843 | ENSG00000007171 | NOS2 | nitric oxide synthase 2, inducible |
| Pathway Commons pathway----Beta1 integrin cell surface interactions----DB_ID:1517 | |||||
| C=1351;O=112;E=10.68;R=10.48;rawP=1.20e-81;adjP=2.54e-79 | |||||
| 6347 | NA | 6347 | ENSG00000108691 | CCL2 | chemokine (C-C motif) ligand 2 |
| 959 | NA | 959 | ENSG00000102245 | CD40LG | CD40 ligand |
| 3791 | NA | 3791 | ENSG00000128052 | KDR | kinase insert domain receptor (a type III receptor tyrosine kinase) |
| 5037 | NA | 5037 | ENSG00000089220 | PEBP1 | phosphatidylethanolamine binding protein 1 |
| 1950 | NA | 1950 | ENSG00000138798 | EGF | epidermal growth factor |
| 3596 | NA | 3596 | ENSG00000169194 | IL13 | interleukin 13 |
| 6648 | NA | 6648 | ENSG00000112096 | SOD2 | superoxide dismutase 2, mitochondrial |
| 7157 | NA | 7157 | ENSG00000141510 | TP53 | tumor protein p53 |
| 331 | NA | 331 | ENSG00000101966 | XIAP | X-linked inhibitor of apoptosis |
| 4090 | NA | 4090 | ENSG00000113658 | SMAD5 | SMAD family member 5 |
| 2355 | NA | 2355 | ENSG00000075426 | FOSL2 | FOS-like antigen 2 |
| 5578 | NA | 5578 | ENSG00000154229 | PRKCA | protein kinase C, alpha |
| 3162 | NA | 3162 | ENSG00000100292 | HMOX1 | heme oxygenase (decycling) 1 |
| 5156 | NA | 5156 | ENSG00000134853 | PDGFRA | platelet-derived growth factor receptor, alpha polypeptide |
| 5566 | NA | 5566 | ENSG00000072062 | PRKACA | protein kinase, cAMP-dependent, catalytic, alpha |
| 5155 | NA | 5155 | ENSG00000100311 | PDGFB | platelet-derived growth factor beta polypeptide |
| 3371 | NA | 3371 | ENSG00000041982 | TNC | tenascin C |
| 7474 | NA | 7474 | ENSG00000114251 | WNT5A | wingless-type MMTV integration site family, member 5A |
| 2022 | NA | 2022 | ENSG00000106991 | ENG | endoglin |
| 595 | NA | 595 | ENSG00000110092 | CCND1 | cyclin D1 |
| 10746 | NA | 10746 | ENSG00000169967 | MAP3K2 | mitogen-activated protein kinase kinase kinase 2 |
| 7049 | NA | 7049 | ENSG00000069702 | TGFBR3 | transforming growth factor, beta receptor III |
| 114907 | NA | 114907 | ENSG00000156804 | FBXO32 | F-box protein 32 |
| 1499 | NA | 1499 | ENSG00000168036 | CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa |
| 1490 | NA | 1490 | ENSG00000118523 | CTGF | connective tissue growth factor |
| 1027 | NA | 1027 | ENSG00000111276 | CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) |
| 4791 | NA | 4791 | ENSG00000077150 | NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) |
| 841 | NA | 841 | ENSG00000064012 | CASP8 | caspase 8, apoptosis-related cysteine peptidase |
| 1401 | NA | 1401 | ENSG00000132693 | CRP | C-reactive protein, pentraxin-related |
| 5159 | NA | 5159 | ENSG00000113721 | PDGFRB | platelet-derived growth factor receptor, beta polypeptide |
| 468 | NA | 468 | ENSG00000128272 | ATF4 | activating transcription factor 4 (tax-responsive enhancer element B67) |
| 207 | NA | 207 | ENSG00000142208 | AKT1 | v-akt murine thymoma viral oncogene homolog 1 |
| 4093 | NA | 4093 | ENSG00000120693 | SMAD9 | SMAD family member 9 |
| 5468 | NA | 5468 | ENSG00000132170 | PPARG | peroxisome proliferator-activated receptor gamma |
| 842 | NA | 842 | ENSG00000132906 | CASP9 | caspase 9, apoptosis-related cysteine peptidase |
| 4035 | NA | 4035 | ENSG00000123384 | LRP1 | low density lipoprotein receptor-related protein 1 |
| 4312 | NA | 4312 | ENSG00000196611 | MMP1 | matrix metallopeptidase 1 (interstitial collagenase) |
| 4773 | NA | 4773 | ENSG00000101096 | NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 |
| 857 | NA | 857 | ENSG00000105974 | CAV1 | caveolin 1, caveolae protein, 22kDa |
| 7422 | NA | 7422 | ENSG00000112715 | VEGFA | vascular endothelial growth factor A |
| 4088 | NA | 4088 | ENSG00000166949 | SMAD3 | SMAD family member 3 |
| 1907 | NA | 1907 | ENSG00000127129 | EDN2 | endothelin 2 |
| 5743 | NA | 5743 | ENSG00000073756 | PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
| 4087 | NA | 4087 | ENSG00000175387 | SMAD2 | SMAD family member 2 |
| 4314 | NA | 4314 | ENSG00000149968 | MMP3 | matrix metallopeptidase 3 (stromelysin 1, progelatinase) |
| 6772 | NA | 6772 | ENSG00000115415 | STAT1 | signal transducer and activator of transcription 1, 91kDa |
| 3065 | NA | 3065 | ENSG00000116478 | HDAC1 | histone deacetylase 1 |
| 3082 | NA | 3082 | ENSG00000019991 | HGF | hepatocyte growth factor (hepapoietin A; scatter factor) |
| 22926 | NA | 22926 | ENSG00000118217 | ATF6 | activating transcription factor 6 |
| 7412 | NA | 7412 | ENSG00000162692 | VCAM1 | vascular cell adhesion molecule 1 |
| 5054 | NA | 5054 | ENSG00000106366 | SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 |
| 657 | NA | 657 | ENSG00000107779 | BMPR1A | bone morphogenetic protein receptor, type IA |
| 7054 | NA | 7054 | ENSG00000180176 | TH | tyrosine hydroxylase |
| 6093 | NA | 6093 | ENSG00000067900 | ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 |
| 4086 | NA | 4086 | ENSG00000170365 | SMAD1 | SMAD family member 1 |
| 10891 | NA | 10891 | ENSG00000109819 | PPARGC1A | peroxisome proliferator-activated receptor gamma, coactivator 1 alpha |
| 5594 | NA | 5594 | ENSG00000100030 | MAPK1 | mitogen-activated protein kinase 1 |
| 57154 | NA | 57154 | ENSG00000198742 | SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 |
| 4089 | NA | 4089 | ENSG00000141646 | SMAD4 | SMAD family member 4 |
| 3598 | NA | 3598 | ENSG00000123496 | IL13RA2 | interleukin 13 receptor, alpha 2 |
| 658 | NA | 658 | ENSG00000138696 | BMPR1B | bone morphogenetic protein receptor, type IB |
| 4318 | NA | 4318 | ENSG00000100985 | MMP9 | matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) |
| 7433 | NA | 7433 | ENSG00000114812 | VIPR1 | vasoactive intestinal peptide receptor 1 |
| 659 | NA | 659 | ENSG00000204217 | BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) |
| 2335 | NA | 2335 | ENSG00000115414 | FN1 | fibronectin 1 |
| 4092 | NA | 4092 | ENSG00000101665 | SMAD7 | SMAD family member 7 |
| 3398 | NA | 3398 | ENSG00000115738 | ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein |
| 7046 | NA | 7046 | ENSG00000106799 | TGFBR1 | transforming growth factor, beta receptor 1 |
| 9518 | NA | 9518 | ENSG00000130513 | GDF15 | growth differentiation factor 15 |
| 7048 | NA | 7048 | ENSG00000163513 | TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) |
| 4485 | NA | 4485 | ENSG00000173531 | MST1 | macrophage stimulating 1 (hepatocyte growth factor-like) |
| 6714 | NA | 6714 | ENSG00000197122 | SRC | v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) |
| 3383 | NA | 3383 | ENSG00000090339 | ICAM1 | intercellular adhesion molecule 1 |
| 7057 | NA | 7057 | ENSG00000137801 | THBS1 | thrombospondin 1 |
| 650 | NA | 650 | ENSG00000125845 | BMP2 | bone morphogenetic protein 2 |
| 3662 | NA | 3662 | ENSG00000137265 | IRF4 | interferon regulatory factor 4 |
| 6696 | NA | 6696 | ENSG00000118785 | SPP1 | secreted phosphoprotein 1 |
| 8600 | NA | 8600 | ENSG00000120659 | TNFSF11 | tumor necrosis factor (ligand) superfamily, member 11 |
| 4775 | NA | 4775 | ENSG00000072736 | NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 |
| 7076 | NA | 7076 | ENSG00000102265 | TIMP1 | TIMP metallopeptidase inhibitor 1 |
| 3480 | NA | 3480 | ENSG00000140443 | IGF1R | insulin-like growth factor 1 receptor |
| 57060 | NA | 57060 | ENSG00000090097 | PCBP4 | poly(rC) binding protein 4 |
| 4313 | NA | 4313 | ENSG00000087245 | MMP2 | matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) |
| 5592 | NA | 5592 | ENSG00000185532 | PRKG1 | protein kinase, cGMP-dependent, type I |
| 3913 | NA | 3913 | ENSG00000172037 | LAMB2 | laminin, beta 2 (laminin S) |
| 3952 | NA | 3952 | ENSG00000174697 | LEP | leptin |
| 1910 | NA | 1910 | ENSG00000136160 | EDNRB | endothelin receptor type B |
| 6387 | NA | 6387 | ENSG00000107562 | CXCL12 | chemokine (C-X-C motif) ligand 12 |
| 5292 | NA | 5292 | ENSG00000137193 | PIM1 | pim-1 oncogene |
| 6774 | NA | 6774 | ENSG00000168610 | STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) |
| 5551 | NA | 5551 | ENSG00000180644 | PRF1 | perforin 1 (pore forming protein) |
| 9475 | NA | 9475 | ENSG00000134318 | ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 |
| 1843 | NA | 1843 | ENSG00000120129 | DUSP1 | dual specificity phosphatase 1 |
| 4846 | NA | 4846 | ENSG00000164867 | NOS3 | nitric oxide synthase 3 (endothelial cell) |
| 7040 | NA | 7040 | ENSG00000105329 | TGFB1 | transforming growth factor, beta 1 |
| 7124 | NA | 7124 | ENSG00000232810 | TNF | tumor necrosis factor |
| 993 | NA | 993 | ENSG00000164045 | CDC25A | cell division cycle 25 homolog A (S. pombe) |
| 26585 | NA | 26585 | ENSG00000166923 | GREM1 | gremlin 1 |
| 387 | NA | 387 | ENSG00000067560 | RHOA | ras homolog family member A |
| 5617 | NA | 5617 | ENSG00000172179 | PRL | prolactin |
| 1906 | NA | 1906 | ENSG00000078401 | EDN1 | endothelin 1 |
| 7045 | NA | 7045 | ENSG00000120708 | TGFBI | transforming growth factor, beta-induced, 68kDa |
| 2353 | NA | 2353 | ENSG00000170345 | FOS | FBJ murine osteosarcoma viral oncogene homolog |
| 1956 | NA | 1956 | ENSG00000146648 | EGFR | epidermal growth factor receptor |
| 1051 | NA | 1051 | ENSG00000172216 | CEBPB | CCAAT/enhancer binding protein (C/EBP), beta |
| 185 | NA | 185 | ENSG00000144891 | AGTR1 | angiotensin II receptor, type 1 |
| 3091 | NA | 3091 | ENSG00000100644 | HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) |
| 3569 | NA | 3569 | ENSG00000136244 | IL6 | interleukin 6 (interferon, beta 2) |
| 3099 | NA | 3099 | ENSG00000159399 | HK2 | hexokinase 2 |
| 652 | NA | 652 | ENSG00000125378 | BMP4 | bone morphogenetic protein 4 |
| 2099 | NA | 2099 | ENSG00000091831 | ESR1 | estrogen receptor 1 |
| 4843 | NA | 4843 | ENSG00000007171 | NOS2 | nitric oxide synthase 2, inducible |
| Pathway Commons pathway----TRAIL signaling pathway----DB_ID:1480 | |||||
| C=1328;O=111;E=10.50;R=10.57;rawP=3.03e-81;adjP=4.27e-79 | |||||
| 6347 | NA | 6347 | ENSG00000108691 | CCL2 | chemokine (C-C motif) ligand 2 |
| 959 | NA | 959 | ENSG00000102245 | CD40LG | CD40 ligand |
| 3791 | NA | 3791 | ENSG00000128052 | KDR | kinase insert domain receptor (a type III receptor tyrosine kinase) |
| 5037 | NA | 5037 | ENSG00000089220 | PEBP1 | phosphatidylethanolamine binding protein 1 |
| 1950 | NA | 1950 | ENSG00000138798 | EGF | epidermal growth factor |
| 3596 | NA | 3596 | ENSG00000169194 | IL13 | interleukin 13 |
| 6648 | NA | 6648 | ENSG00000112096 | SOD2 | superoxide dismutase 2, mitochondrial |
| 7157 | NA | 7157 | ENSG00000141510 | TP53 | tumor protein p53 |
| 331 | NA | 331 | ENSG00000101966 | XIAP | X-linked inhibitor of apoptosis |
| 4090 | NA | 4090 | ENSG00000113658 | SMAD5 | SMAD family member 5 |
| 2355 | NA | 2355 | ENSG00000075426 | FOSL2 | FOS-like antigen 2 |
| 5578 | NA | 5578 | ENSG00000154229 | PRKCA | protein kinase C, alpha |
| 3162 | NA | 3162 | ENSG00000100292 | HMOX1 | heme oxygenase (decycling) 1 |
| 5156 | NA | 5156 | ENSG00000134853 | PDGFRA | platelet-derived growth factor receptor, alpha polypeptide |
| 5566 | NA | 5566 | ENSG00000072062 | PRKACA | protein kinase, cAMP-dependent, catalytic, alpha |
| 5155 | NA | 5155 | ENSG00000100311 | PDGFB | platelet-derived growth factor beta polypeptide |
| 7474 | NA | 7474 | ENSG00000114251 | WNT5A | wingless-type MMTV integration site family, member 5A |
| 5154 | NA | 5154 | ENSG00000197461 | PDGFA | platelet-derived growth factor alpha polypeptide |
| 2022 | NA | 2022 | ENSG00000106991 | ENG | endoglin |
| 595 | NA | 595 | ENSG00000110092 | CCND1 | cyclin D1 |
| 10746 | NA | 10746 | ENSG00000169967 | MAP3K2 | mitogen-activated protein kinase kinase kinase 2 |
| 7049 | NA | 7049 | ENSG00000069702 | TGFBR3 | transforming growth factor, beta receptor III |
| 114907 | NA | 114907 | ENSG00000156804 | FBXO32 | F-box protein 32 |
| 1499 | NA | 1499 | ENSG00000168036 | CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa |
| 1490 | NA | 1490 | ENSG00000118523 | CTGF | connective tissue growth factor |
| 1027 | NA | 1027 | ENSG00000111276 | CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) |
| 4791 | NA | 4791 | ENSG00000077150 | NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) |
| 841 | NA | 841 | ENSG00000064012 | CASP8 | caspase 8, apoptosis-related cysteine peptidase |
| 1401 | NA | 1401 | ENSG00000132693 | CRP | C-reactive protein, pentraxin-related |
| 5159 | NA | 5159 | ENSG00000113721 | PDGFRB | platelet-derived growth factor receptor, beta polypeptide |
| 468 | NA | 468 | ENSG00000128272 | ATF4 | activating transcription factor 4 (tax-responsive enhancer element B67) |
| 207 | NA | 207 | ENSG00000142208 | AKT1 | v-akt murine thymoma viral oncogene homolog 1 |
| 4093 | NA | 4093 | ENSG00000120693 | SMAD9 | SMAD family member 9 |
| 5468 | NA | 5468 | ENSG00000132170 | PPARG | peroxisome proliferator-activated receptor gamma |
| 842 | NA | 842 | ENSG00000132906 | CASP9 | caspase 9, apoptosis-related cysteine peptidase |
| 4035 | NA | 4035 | ENSG00000123384 | LRP1 | low density lipoprotein receptor-related protein 1 |
| 4312 | NA | 4312 | ENSG00000196611 | MMP1 | matrix metallopeptidase 1 (interstitial collagenase) |
| 8743 | NA | 8743 | ENSG00000121858 | TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 |
| 4773 | NA | 4773 | ENSG00000101096 | NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 |
| 857 | NA | 857 | ENSG00000105974 | CAV1 | caveolin 1, caveolae protein, 22kDa |
| 7422 | NA | 7422 | ENSG00000112715 | VEGFA | vascular endothelial growth factor A |
| 4088 | NA | 4088 | ENSG00000166949 | SMAD3 | SMAD family member 3 |
| 1907 | NA | 1907 | ENSG00000127129 | EDN2 | endothelin 2 |
| 5743 | NA | 5743 | ENSG00000073756 | PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
| 4087 | NA | 4087 | ENSG00000175387 | SMAD2 | SMAD family member 2 |
| 4314 | NA | 4314 | ENSG00000149968 | MMP3 | matrix metallopeptidase 3 (stromelysin 1, progelatinase) |
| 3984 | NA | 3984 | ENSG00000106683 | LIMK1 | LIM domain kinase 1 |
| 6772 | NA | 6772 | ENSG00000115415 | STAT1 | signal transducer and activator of transcription 1, 91kDa |
| 3065 | NA | 3065 | ENSG00000116478 | HDAC1 | histone deacetylase 1 |
| 3082 | NA | 3082 | ENSG00000019991 | HGF | hepatocyte growth factor (hepapoietin A; scatter factor) |
| 22926 | NA | 22926 | ENSG00000118217 | ATF6 | activating transcription factor 6 |
| 5054 | NA | 5054 | ENSG00000106366 | SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 |
| 657 | NA | 657 | ENSG00000107779 | BMPR1A | bone morphogenetic protein receptor, type IA |
| 7054 | NA | 7054 | ENSG00000180176 | TH | tyrosine hydroxylase |
| 6093 | NA | 6093 | ENSG00000067900 | ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 |
| 4086 | NA | 4086 | ENSG00000170365 | SMAD1 | SMAD family member 1 |
| 10891 | NA | 10891 | ENSG00000109819 | PPARGC1A | peroxisome proliferator-activated receptor gamma, coactivator 1 alpha |
| 5594 | NA | 5594 | ENSG00000100030 | MAPK1 | mitogen-activated protein kinase 1 |
| 57154 | NA | 57154 | ENSG00000198742 | SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 |
| 4089 | NA | 4089 | ENSG00000141646 | SMAD4 | SMAD family member 4 |
| 3598 | NA | 3598 | ENSG00000123496 | IL13RA2 | interleukin 13 receptor, alpha 2 |
| 658 | NA | 658 | ENSG00000138696 | BMPR1B | bone morphogenetic protein receptor, type IB |
| 4318 | NA | 4318 | ENSG00000100985 | MMP9 | matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) |
| 7433 | NA | 7433 | ENSG00000114812 | VIPR1 | vasoactive intestinal peptide receptor 1 |
| 659 | NA | 659 | ENSG00000204217 | BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) |
| 2335 | NA | 2335 | ENSG00000115414 | FN1 | fibronectin 1 |
| 4092 | NA | 4092 | ENSG00000101665 | SMAD7 | SMAD family member 7 |
| 3398 | NA | 3398 | ENSG00000115738 | ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein |
| 7046 | NA | 7046 | ENSG00000106799 | TGFBR1 | transforming growth factor, beta receptor 1 |
| 9518 | NA | 9518 | ENSG00000130513 | GDF15 | growth differentiation factor 15 |
| 7048 | NA | 7048 | ENSG00000163513 | TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) |
| 4485 | NA | 4485 | ENSG00000173531 | MST1 | macrophage stimulating 1 (hepatocyte growth factor-like) |
| 6714 | NA | 6714 | ENSG00000197122 | SRC | v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) |
| 3383 | NA | 3383 | ENSG00000090339 | ICAM1 | intercellular adhesion molecule 1 |
| 650 | NA | 650 | ENSG00000125845 | BMP2 | bone morphogenetic protein 2 |
| 3662 | NA | 3662 | ENSG00000137265 | IRF4 | interferon regulatory factor 4 |
| 6696 | NA | 6696 | ENSG00000118785 | SPP1 | secreted phosphoprotein 1 |
| 8600 | NA | 8600 | ENSG00000120659 | TNFSF11 | tumor necrosis factor (ligand) superfamily, member 11 |
| 4775 | NA | 4775 | ENSG00000072736 | NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 |
| 7076 | NA | 7076 | ENSG00000102265 | TIMP1 | TIMP metallopeptidase inhibitor 1 |
| 3480 | NA | 3480 | ENSG00000140443 | IGF1R | insulin-like growth factor 1 receptor |
| 57060 | NA | 57060 | ENSG00000090097 | PCBP4 | poly(rC) binding protein 4 |
| 4313 | NA | 4313 | ENSG00000087245 | MMP2 | matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) |
| 5592 | NA | 5592 | ENSG00000185532 | PRKG1 | protein kinase, cGMP-dependent, type I |
| 3952 | NA | 3952 | ENSG00000174697 | LEP | leptin |
| 1910 | NA | 1910 | ENSG00000136160 | EDNRB | endothelin receptor type B |
| 6387 | NA | 6387 | ENSG00000107562 | CXCL12 | chemokine (C-X-C motif) ligand 12 |
| 5292 | NA | 5292 | ENSG00000137193 | PIM1 | pim-1 oncogene |
| 6774 | NA | 6774 | ENSG00000168610 | STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) |
| 5551 | NA | 5551 | ENSG00000180644 | PRF1 | perforin 1 (pore forming protein) |
| 9475 | NA | 9475 | ENSG00000134318 | ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 |
| 1843 | NA | 1843 | ENSG00000120129 | DUSP1 | dual specificity phosphatase 1 |
| 4846 | NA | 4846 | ENSG00000164867 | NOS3 | nitric oxide synthase 3 (endothelial cell) |
| 7040 | NA | 7040 | ENSG00000105329 | TGFB1 | transforming growth factor, beta 1 |
| 7124 | NA | 7124 | ENSG00000232810 | TNF | tumor necrosis factor |
| 993 | NA | 993 | ENSG00000164045 | CDC25A | cell division cycle 25 homolog A (S. pombe) |
| 26585 | NA | 26585 | ENSG00000166923 | GREM1 | gremlin 1 |
| 387 | NA | 387 | ENSG00000067560 | RHOA | ras homolog family member A |
| 5617 | NA | 5617 | ENSG00000172179 | PRL | prolactin |
| 1906 | NA | 1906 | ENSG00000078401 | EDN1 | endothelin 1 |
| 2353 | NA | 2353 | ENSG00000170345 | FOS | FBJ murine osteosarcoma viral oncogene homolog |
| 1073 | NA | 1073 | ENSG00000165410 | CFL2 | cofilin 2 (muscle) |
| 1956 | NA | 1956 | ENSG00000146648 | EGFR | epidermal growth factor receptor |
| 1051 | NA | 1051 | ENSG00000172216 | CEBPB | CCAAT/enhancer binding protein (C/EBP), beta |
| 185 | NA | 185 | ENSG00000144891 | AGTR1 | angiotensin II receptor, type 1 |
| 3091 | NA | 3091 | ENSG00000100644 | HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) |
| 3569 | NA | 3569 | ENSG00000136244 | IL6 | interleukin 6 (interferon, beta 2) |
| 3099 | NA | 3099 | ENSG00000159399 | HK2 | hexokinase 2 |
| 652 | NA | 652 | ENSG00000125378 | BMP4 | bone morphogenetic protein 4 |
| 2099 | NA | 2099 | ENSG00000091831 | ESR1 | estrogen receptor 1 |
| 4843 | NA | 4843 | ENSG00000007171 | NOS2 | nitric oxide synthase 2, inducible |
| Pathway Commons pathway----Endothelins----DB_ID:1619 | |||||
| C=1307;O=110;E=10.33;R=10.64;rawP=8.96e-81;adjP=9.48e-79 | |||||
| 6347 | NA | 6347 | ENSG00000108691 | CCL2 | chemokine (C-C motif) ligand 2 |
| 959 | NA | 959 | ENSG00000102245 | CD40LG | CD40 ligand |
| 3791 | NA | 3791 | ENSG00000128052 | KDR | kinase insert domain receptor (a type III receptor tyrosine kinase) |
| 5037 | NA | 5037 | ENSG00000089220 | PEBP1 | phosphatidylethanolamine binding protein 1 |
| 1950 | NA | 1950 | ENSG00000138798 | EGF | epidermal growth factor |
| 3596 | NA | 3596 | ENSG00000169194 | IL13 | interleukin 13 |
| 6648 | NA | 6648 | ENSG00000112096 | SOD2 | superoxide dismutase 2, mitochondrial |
| 7157 | NA | 7157 | ENSG00000141510 | TP53 | tumor protein p53 |
| 331 | NA | 331 | ENSG00000101966 | XIAP | X-linked inhibitor of apoptosis |
| 4090 | NA | 4090 | ENSG00000113658 | SMAD5 | SMAD family member 5 |
| 2355 | NA | 2355 | ENSG00000075426 | FOSL2 | FOS-like antigen 2 |
| 5578 | NA | 5578 | ENSG00000154229 | PRKCA | protein kinase C, alpha |
| 3162 | NA | 3162 | ENSG00000100292 | HMOX1 | heme oxygenase (decycling) 1 |
| 5156 | NA | 5156 | ENSG00000134853 | PDGFRA | platelet-derived growth factor receptor, alpha polypeptide |
| 5566 | NA | 5566 | ENSG00000072062 | PRKACA | protein kinase, cAMP-dependent, catalytic, alpha |
| 5155 | NA | 5155 | ENSG00000100311 | PDGFB | platelet-derived growth factor beta polypeptide |
| 7474 | NA | 7474 | ENSG00000114251 | WNT5A | wingless-type MMTV integration site family, member 5A |
| 2022 | NA | 2022 | ENSG00000106991 | ENG | endoglin |
| 595 | NA | 595 | ENSG00000110092 | CCND1 | cyclin D1 |
| 10746 | NA | 10746 | ENSG00000169967 | MAP3K2 | mitogen-activated protein kinase kinase kinase 2 |
| 7049 | NA | 7049 | ENSG00000069702 | TGFBR3 | transforming growth factor, beta receptor III |
| 114907 | NA | 114907 | ENSG00000156804 | FBXO32 | F-box protein 32 |
| 1499 | NA | 1499 | ENSG00000168036 | CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa |
| 1490 | NA | 1490 | ENSG00000118523 | CTGF | connective tissue growth factor |
| 1027 | NA | 1027 | ENSG00000111276 | CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) |
| 4791 | NA | 4791 | ENSG00000077150 | NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) |
| 841 | NA | 841 | ENSG00000064012 | CASP8 | caspase 8, apoptosis-related cysteine peptidase |
| 1401 | NA | 1401 | ENSG00000132693 | CRP | C-reactive protein, pentraxin-related |
| 5159 | NA | 5159 | ENSG00000113721 | PDGFRB | platelet-derived growth factor receptor, beta polypeptide |
| 468 | NA | 468 | ENSG00000128272 | ATF4 | activating transcription factor 4 (tax-responsive enhancer element B67) |
| 207 | NA | 207 | ENSG00000142208 | AKT1 | v-akt murine thymoma viral oncogene homolog 1 |
| 4093 | NA | 4093 | ENSG00000120693 | SMAD9 | SMAD family member 9 |
| 5468 | NA | 5468 | ENSG00000132170 | PPARG | peroxisome proliferator-activated receptor gamma |
| 842 | NA | 842 | ENSG00000132906 | CASP9 | caspase 9, apoptosis-related cysteine peptidase |
| 4035 | NA | 4035 | ENSG00000123384 | LRP1 | low density lipoprotein receptor-related protein 1 |
| 4312 | NA | 4312 | ENSG00000196611 | MMP1 | matrix metallopeptidase 1 (interstitial collagenase) |
| 4773 | NA | 4773 | ENSG00000101096 | NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 |
| 857 | NA | 857 | ENSG00000105974 | CAV1 | caveolin 1, caveolae protein, 22kDa |
| 7422 | NA | 7422 | ENSG00000112715 | VEGFA | vascular endothelial growth factor A |
| 1909 | NA | 1909 | ENSG00000151617 | EDNRA | endothelin receptor type A |
| 4088 | NA | 4088 | ENSG00000166949 | SMAD3 | SMAD family member 3 |
| 1907 | NA | 1907 | ENSG00000127129 | EDN2 | endothelin 2 |
| 5743 | NA | 5743 | ENSG00000073756 | PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
| 4087 | NA | 4087 | ENSG00000175387 | SMAD2 | SMAD family member 2 |
| 4314 | NA | 4314 | ENSG00000149968 | MMP3 | matrix metallopeptidase 3 (stromelysin 1, progelatinase) |
| 7225 | NA | 7225 | ENSG00000137672 | TRPC6 | transient receptor potential cation channel, subfamily C, member 6 |
| 6772 | NA | 6772 | ENSG00000115415 | STAT1 | signal transducer and activator of transcription 1, 91kDa |
| 3065 | NA | 3065 | ENSG00000116478 | HDAC1 | histone deacetylase 1 |
| 3082 | NA | 3082 | ENSG00000019991 | HGF | hepatocyte growth factor (hepapoietin A; scatter factor) |
| 22926 | NA | 22926 | ENSG00000118217 | ATF6 | activating transcription factor 6 |
| 5054 | NA | 5054 | ENSG00000106366 | SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 |
| 657 | NA | 657 | ENSG00000107779 | BMPR1A | bone morphogenetic protein receptor, type IA |
| 7054 | NA | 7054 | ENSG00000180176 | TH | tyrosine hydroxylase |
| 6093 | NA | 6093 | ENSG00000067900 | ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 |
| 4086 | NA | 4086 | ENSG00000170365 | SMAD1 | SMAD family member 1 |
| 10891 | NA | 10891 | ENSG00000109819 | PPARGC1A | peroxisome proliferator-activated receptor gamma, coactivator 1 alpha |
| 5594 | NA | 5594 | ENSG00000100030 | MAPK1 | mitogen-activated protein kinase 1 |
| 57154 | NA | 57154 | ENSG00000198742 | SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 |
| 4089 | NA | 4089 | ENSG00000141646 | SMAD4 | SMAD family member 4 |
| 3598 | NA | 3598 | ENSG00000123496 | IL13RA2 | interleukin 13 receptor, alpha 2 |
| 658 | NA | 658 | ENSG00000138696 | BMPR1B | bone morphogenetic protein receptor, type IB |
| 4318 | NA | 4318 | ENSG00000100985 | MMP9 | matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) |
| 7433 | NA | 7433 | ENSG00000114812 | VIPR1 | vasoactive intestinal peptide receptor 1 |
| 659 | NA | 659 | ENSG00000204217 | BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) |
| 1908 | NA | 1908 | ENSG00000124205 | EDN3 | endothelin 3 |
| 2335 | NA | 2335 | ENSG00000115414 | FN1 | fibronectin 1 |
| 4092 | NA | 4092 | ENSG00000101665 | SMAD7 | SMAD family member 7 |
| 3398 | NA | 3398 | ENSG00000115738 | ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein |
| 7046 | NA | 7046 | ENSG00000106799 | TGFBR1 | transforming growth factor, beta receptor 1 |
| 9518 | NA | 9518 | ENSG00000130513 | GDF15 | growth differentiation factor 15 |
| 7048 | NA | 7048 | ENSG00000163513 | TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) |
| 4485 | NA | 4485 | ENSG00000173531 | MST1 | macrophage stimulating 1 (hepatocyte growth factor-like) |
| 6714 | NA | 6714 | ENSG00000197122 | SRC | v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) |
| 3383 | NA | 3383 | ENSG00000090339 | ICAM1 | intercellular adhesion molecule 1 |
| 650 | NA | 650 | ENSG00000125845 | BMP2 | bone morphogenetic protein 2 |
| 3662 | NA | 3662 | ENSG00000137265 | IRF4 | interferon regulatory factor 4 |
| 6696 | NA | 6696 | ENSG00000118785 | SPP1 | secreted phosphoprotein 1 |
| 8600 | NA | 8600 | ENSG00000120659 | TNFSF11 | tumor necrosis factor (ligand) superfamily, member 11 |
| 4775 | NA | 4775 | ENSG00000072736 | NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 |
| 7076 | NA | 7076 | ENSG00000102265 | TIMP1 | TIMP metallopeptidase inhibitor 1 |
| 3480 | NA | 3480 | ENSG00000140443 | IGF1R | insulin-like growth factor 1 receptor |
| 57060 | NA | 57060 | ENSG00000090097 | PCBP4 | poly(rC) binding protein 4 |
| 4313 | NA | 4313 | ENSG00000087245 | MMP2 | matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) |
| 5592 | NA | 5592 | ENSG00000185532 | PRKG1 | protein kinase, cGMP-dependent, type I |
| 3952 | NA | 3952 | ENSG00000174697 | LEP | leptin |
| 1910 | NA | 1910 | ENSG00000136160 | EDNRB | endothelin receptor type B |
| 6387 | NA | 6387 | ENSG00000107562 | CXCL12 | chemokine (C-X-C motif) ligand 12 |
| 5292 | NA | 5292 | ENSG00000137193 | PIM1 | pim-1 oncogene |
| 6774 | NA | 6774 | ENSG00000168610 | STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) |
| 5551 | NA | 5551 | ENSG00000180644 | PRF1 | perforin 1 (pore forming protein) |
| 9475 | NA | 9475 | ENSG00000134318 | ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 |
| 1843 | NA | 1843 | ENSG00000120129 | DUSP1 | dual specificity phosphatase 1 |
| 4846 | NA | 4846 | ENSG00000164867 | NOS3 | nitric oxide synthase 3 (endothelial cell) |
| 7040 | NA | 7040 | ENSG00000105329 | TGFB1 | transforming growth factor, beta 1 |
| 7124 | NA | 7124 | ENSG00000232810 | TNF | tumor necrosis factor |
| 993 | NA | 993 | ENSG00000164045 | CDC25A | cell division cycle 25 homolog A (S. pombe) |
| 26585 | NA | 26585 | ENSG00000166923 | GREM1 | gremlin 1 |
| 387 | NA | 387 | ENSG00000067560 | RHOA | ras homolog family member A |
| 5617 | NA | 5617 | ENSG00000172179 | PRL | prolactin |
| 1906 | NA | 1906 | ENSG00000078401 | EDN1 | endothelin 1 |
| 2353 | NA | 2353 | ENSG00000170345 | FOS | FBJ murine osteosarcoma viral oncogene homolog |
| 1956 | NA | 1956 | ENSG00000146648 | EGFR | epidermal growth factor receptor |
| 1051 | NA | 1051 | ENSG00000172216 | CEBPB | CCAAT/enhancer binding protein (C/EBP), beta |
| 185 | NA | 185 | ENSG00000144891 | AGTR1 | angiotensin II receptor, type 1 |
| 3091 | NA | 3091 | ENSG00000100644 | HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) |
| 3569 | NA | 3569 | ENSG00000136244 | IL6 | interleukin 6 (interferon, beta 2) |
| 3099 | NA | 3099 | ENSG00000159399 | HK2 | hexokinase 2 |
| 652 | NA | 652 | ENSG00000125378 | BMP4 | bone morphogenetic protein 4 |
| 2099 | NA | 2099 | ENSG00000091831 | ESR1 | estrogen receptor 1 |
| 4843 | NA | 4843 | ENSG00000007171 | NOS2 | nitric oxide synthase 2, inducible |
| Pathway Commons pathway----Plasma membrane estrogen receptor signaling----DB_ID:1556 | |||||
| C=1301;O=109;E=10.29;R=10.60;rawP=9.04e-80;adjP=7.65e-78 | |||||
| 6347 | NA | 6347 | ENSG00000108691 | CCL2 | chemokine (C-C motif) ligand 2 |
| 959 | NA | 959 | ENSG00000102245 | CD40LG | CD40 ligand |
| 3791 | NA | 3791 | ENSG00000128052 | KDR | kinase insert domain receptor (a type III receptor tyrosine kinase) |
| 5037 | NA | 5037 | ENSG00000089220 | PEBP1 | phosphatidylethanolamine binding protein 1 |
| 1950 | NA | 1950 | ENSG00000138798 | EGF | epidermal growth factor |
| 3596 | NA | 3596 | ENSG00000169194 | IL13 | interleukin 13 |
| 6648 | NA | 6648 | ENSG00000112096 | SOD2 | superoxide dismutase 2, mitochondrial |
| 7157 | NA | 7157 | ENSG00000141510 | TP53 | tumor protein p53 |
| 331 | NA | 331 | ENSG00000101966 | XIAP | X-linked inhibitor of apoptosis |
| 4090 | NA | 4090 | ENSG00000113658 | SMAD5 | SMAD family member 5 |
| 2355 | NA | 2355 | ENSG00000075426 | FOSL2 | FOS-like antigen 2 |
| 5578 | NA | 5578 | ENSG00000154229 | PRKCA | protein kinase C, alpha |
| 3162 | NA | 3162 | ENSG00000100292 | HMOX1 | heme oxygenase (decycling) 1 |
| 5156 | NA | 5156 | ENSG00000134853 | PDGFRA | platelet-derived growth factor receptor, alpha polypeptide |
| 5566 | NA | 5566 | ENSG00000072062 | PRKACA | protein kinase, cAMP-dependent, catalytic, alpha |
| 5155 | NA | 5155 | ENSG00000100311 | PDGFB | platelet-derived growth factor beta polypeptide |
| 7474 | NA | 7474 | ENSG00000114251 | WNT5A | wingless-type MMTV integration site family, member 5A |
| 2022 | NA | 2022 | ENSG00000106991 | ENG | endoglin |
| 595 | NA | 595 | ENSG00000110092 | CCND1 | cyclin D1 |
| 10746 | NA | 10746 | ENSG00000169967 | MAP3K2 | mitogen-activated protein kinase kinase kinase 2 |
| 7049 | NA | 7049 | ENSG00000069702 | TGFBR3 | transforming growth factor, beta receptor III |
| 114907 | NA | 114907 | ENSG00000156804 | FBXO32 | F-box protein 32 |
| 1499 | NA | 1499 | ENSG00000168036 | CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa |
| 1490 | NA | 1490 | ENSG00000118523 | CTGF | connective tissue growth factor |
| 1027 | NA | 1027 | ENSG00000111276 | CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) |
| 4791 | NA | 4791 | ENSG00000077150 | NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) |
| 841 | NA | 841 | ENSG00000064012 | CASP8 | caspase 8, apoptosis-related cysteine peptidase |
| 1401 | NA | 1401 | ENSG00000132693 | CRP | C-reactive protein, pentraxin-related |
| 5159 | NA | 5159 | ENSG00000113721 | PDGFRB | platelet-derived growth factor receptor, beta polypeptide |
| 468 | NA | 468 | ENSG00000128272 | ATF4 | activating transcription factor 4 (tax-responsive enhancer element B67) |
| 207 | NA | 207 | ENSG00000142208 | AKT1 | v-akt murine thymoma viral oncogene homolog 1 |
| 4093 | NA | 4093 | ENSG00000120693 | SMAD9 | SMAD family member 9 |
| 5468 | NA | 5468 | ENSG00000132170 | PPARG | peroxisome proliferator-activated receptor gamma |
| 842 | NA | 842 | ENSG00000132906 | CASP9 | caspase 9, apoptosis-related cysteine peptidase |
| 4035 | NA | 4035 | ENSG00000123384 | LRP1 | low density lipoprotein receptor-related protein 1 |
| 4312 | NA | 4312 | ENSG00000196611 | MMP1 | matrix metallopeptidase 1 (interstitial collagenase) |
| 4773 | NA | 4773 | ENSG00000101096 | NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 |
| 857 | NA | 857 | ENSG00000105974 | CAV1 | caveolin 1, caveolae protein, 22kDa |
| 7422 | NA | 7422 | ENSG00000112715 | VEGFA | vascular endothelial growth factor A |
| 4088 | NA | 4088 | ENSG00000166949 | SMAD3 | SMAD family member 3 |
| 1907 | NA | 1907 | ENSG00000127129 | EDN2 | endothelin 2 |
| 5743 | NA | 5743 | ENSG00000073756 | PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
| 4087 | NA | 4087 | ENSG00000175387 | SMAD2 | SMAD family member 2 |
| 4314 | NA | 4314 | ENSG00000149968 | MMP3 | matrix metallopeptidase 3 (stromelysin 1, progelatinase) |
| 6772 | NA | 6772 | ENSG00000115415 | STAT1 | signal transducer and activator of transcription 1, 91kDa |
| 3065 | NA | 3065 | ENSG00000116478 | HDAC1 | histone deacetylase 1 |
| 3082 | NA | 3082 | ENSG00000019991 | HGF | hepatocyte growth factor (hepapoietin A; scatter factor) |
| 22926 | NA | 22926 | ENSG00000118217 | ATF6 | activating transcription factor 6 |
| 5054 | NA | 5054 | ENSG00000106366 | SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 |
| 657 | NA | 657 | ENSG00000107779 | BMPR1A | bone morphogenetic protein receptor, type IA |
| 7054 | NA | 7054 | ENSG00000180176 | TH | tyrosine hydroxylase |
| 6093 | NA | 6093 | ENSG00000067900 | ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 |
| 4086 | NA | 4086 | ENSG00000170365 | SMAD1 | SMAD family member 1 |
| 10891 | NA | 10891 | ENSG00000109819 | PPARGC1A | peroxisome proliferator-activated receptor gamma, coactivator 1 alpha |
| 5594 | NA | 5594 | ENSG00000100030 | MAPK1 | mitogen-activated protein kinase 1 |
| 57154 | NA | 57154 | ENSG00000198742 | SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 |
| 4089 | NA | 4089 | ENSG00000141646 | SMAD4 | SMAD family member 4 |
| 3598 | NA | 3598 | ENSG00000123496 | IL13RA2 | interleukin 13 receptor, alpha 2 |
| 658 | NA | 658 | ENSG00000138696 | BMPR1B | bone morphogenetic protein receptor, type IB |
| 4318 | NA | 4318 | ENSG00000100985 | MMP9 | matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) |
| 7433 | NA | 7433 | ENSG00000114812 | VIPR1 | vasoactive intestinal peptide receptor 1 |
| 659 | NA | 659 | ENSG00000204217 | BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) |
| 2335 | NA | 2335 | ENSG00000115414 | FN1 | fibronectin 1 |
| 4092 | NA | 4092 | ENSG00000101665 | SMAD7 | SMAD family member 7 |
| 3398 | NA | 3398 | ENSG00000115738 | ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein |
| 7046 | NA | 7046 | ENSG00000106799 | TGFBR1 | transforming growth factor, beta receptor 1 |
| 9518 | NA | 9518 | ENSG00000130513 | GDF15 | growth differentiation factor 15 |
| 7048 | NA | 7048 | ENSG00000163513 | TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) |
| 4485 | NA | 4485 | ENSG00000173531 | MST1 | macrophage stimulating 1 (hepatocyte growth factor-like) |
| 6714 | NA | 6714 | ENSG00000197122 | SRC | v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) |
| 3383 | NA | 3383 | ENSG00000090339 | ICAM1 | intercellular adhesion molecule 1 |
| 650 | NA | 650 | ENSG00000125845 | BMP2 | bone morphogenetic protein 2 |
| 3662 | NA | 3662 | ENSG00000137265 | IRF4 | interferon regulatory factor 4 |
| 6696 | NA | 6696 | ENSG00000118785 | SPP1 | secreted phosphoprotein 1 |
| 8600 | NA | 8600 | ENSG00000120659 | TNFSF11 | tumor necrosis factor (ligand) superfamily, member 11 |
| 4775 | NA | 4775 | ENSG00000072736 | NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 |
| 7076 | NA | 7076 | ENSG00000102265 | TIMP1 | TIMP metallopeptidase inhibitor 1 |
| 3480 | NA | 3480 | ENSG00000140443 | IGF1R | insulin-like growth factor 1 receptor |
| 57060 | NA | 57060 | ENSG00000090097 | PCBP4 | poly(rC) binding protein 4 |
| 4313 | NA | 4313 | ENSG00000087245 | MMP2 | matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) |
| 5592 | NA | 5592 | ENSG00000185532 | PRKG1 | protein kinase, cGMP-dependent, type I |
| 3952 | NA | 3952 | ENSG00000174697 | LEP | leptin |
| 1910 | NA | 1910 | ENSG00000136160 | EDNRB | endothelin receptor type B |
| 6387 | NA | 6387 | ENSG00000107562 | CXCL12 | chemokine (C-X-C motif) ligand 12 |
| 5292 | NA | 5292 | ENSG00000137193 | PIM1 | pim-1 oncogene |
| 6774 | NA | 6774 | ENSG00000168610 | STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) |
| 5551 | NA | 5551 | ENSG00000180644 | PRF1 | perforin 1 (pore forming protein) |
| 9475 | NA | 9475 | ENSG00000134318 | ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 |
| 1843 | NA | 1843 | ENSG00000120129 | DUSP1 | dual specificity phosphatase 1 |
| 4846 | NA | 4846 | ENSG00000164867 | NOS3 | nitric oxide synthase 3 (endothelial cell) |
| 7040 | NA | 7040 | ENSG00000105329 | TGFB1 | transforming growth factor, beta 1 |
| 7124 | NA | 7124 | ENSG00000232810 | TNF | tumor necrosis factor |
| 993 | NA | 993 | ENSG00000164045 | CDC25A | cell division cycle 25 homolog A (S. pombe) |
| 26585 | NA | 26585 | ENSG00000166923 | GREM1 | gremlin 1 |
| 387 | NA | 387 | ENSG00000067560 | RHOA | ras homolog family member A |
| 5617 | NA | 5617 | ENSG00000172179 | PRL | prolactin |
| 1906 | NA | 1906 | ENSG00000078401 | EDN1 | endothelin 1 |
| 10399 | NA | 10399 | ENSG00000204628 | GNB2L1 | guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 |
| 2100 | NA | 2100 | ENSG00000140009 | ESR2 | estrogen receptor 2 (ER beta) |
| 2353 | NA | 2353 | ENSG00000170345 | FOS | FBJ murine osteosarcoma viral oncogene homolog |
| 1956 | NA | 1956 | ENSG00000146648 | EGFR | epidermal growth factor receptor |
| 1051 | NA | 1051 | ENSG00000172216 | CEBPB | CCAAT/enhancer binding protein (C/EBP), beta |
| 185 | NA | 185 | ENSG00000144891 | AGTR1 | angiotensin II receptor, type 1 |
| 3091 | NA | 3091 | ENSG00000100644 | HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) |
| 3569 | NA | 3569 | ENSG00000136244 | IL6 | interleukin 6 (interferon, beta 2) |
| 3099 | NA | 3099 | ENSG00000159399 | HK2 | hexokinase 2 |
| 652 | NA | 652 | ENSG00000125378 | BMP4 | bone morphogenetic protein 4 |
| 2099 | NA | 2099 | ENSG00000091831 | ESR1 | estrogen receptor 1 |
| 4843 | NA | 4843 | ENSG00000007171 | NOS2 | nitric oxide synthase 2, inducible |
| Pathway Commons pathway----Alpha9 beta1 integrin signaling events----DB_ID:1578 | |||||
| C=1305;O=109;E=10.32;R=10.56;rawP=1.25e-79;adjP=8.81e-78 | |||||
| 6347 | NA | 6347 | ENSG00000108691 | CCL2 | chemokine (C-C motif) ligand 2 |
| 959 | NA | 959 | ENSG00000102245 | CD40LG | CD40 ligand |
| 3791 | NA | 3791 | ENSG00000128052 | KDR | kinase insert domain receptor (a type III receptor tyrosine kinase) |
| 5037 | NA | 5037 | ENSG00000089220 | PEBP1 | phosphatidylethanolamine binding protein 1 |
| 1950 | NA | 1950 | ENSG00000138798 | EGF | epidermal growth factor |
| 3596 | NA | 3596 | ENSG00000169194 | IL13 | interleukin 13 |
| 6648 | NA | 6648 | ENSG00000112096 | SOD2 | superoxide dismutase 2, mitochondrial |
| 7157 | NA | 7157 | ENSG00000141510 | TP53 | tumor protein p53 |
| 331 | NA | 331 | ENSG00000101966 | XIAP | X-linked inhibitor of apoptosis |
| 4090 | NA | 4090 | ENSG00000113658 | SMAD5 | SMAD family member 5 |
| 2355 | NA | 2355 | ENSG00000075426 | FOSL2 | FOS-like antigen 2 |
| 5578 | NA | 5578 | ENSG00000154229 | PRKCA | protein kinase C, alpha |
| 3162 | NA | 3162 | ENSG00000100292 | HMOX1 | heme oxygenase (decycling) 1 |
| 5156 | NA | 5156 | ENSG00000134853 | PDGFRA | platelet-derived growth factor receptor, alpha polypeptide |
| 5566 | NA | 5566 | ENSG00000072062 | PRKACA | protein kinase, cAMP-dependent, catalytic, alpha |
| 5155 | NA | 5155 | ENSG00000100311 | PDGFB | platelet-derived growth factor beta polypeptide |
| 3371 | NA | 3371 | ENSG00000041982 | TNC | tenascin C |
| 7474 | NA | 7474 | ENSG00000114251 | WNT5A | wingless-type MMTV integration site family, member 5A |
| 2022 | NA | 2022 | ENSG00000106991 | ENG | endoglin |
| 595 | NA | 595 | ENSG00000110092 | CCND1 | cyclin D1 |
| 10746 | NA | 10746 | ENSG00000169967 | MAP3K2 | mitogen-activated protein kinase kinase kinase 2 |
| 7049 | NA | 7049 | ENSG00000069702 | TGFBR3 | transforming growth factor, beta receptor III |
| 114907 | NA | 114907 | ENSG00000156804 | FBXO32 | F-box protein 32 |
| 1499 | NA | 1499 | ENSG00000168036 | CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa |
| 1490 | NA | 1490 | ENSG00000118523 | CTGF | connective tissue growth factor |
| 1027 | NA | 1027 | ENSG00000111276 | CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) |
| 4791 | NA | 4791 | ENSG00000077150 | NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) |
| 841 | NA | 841 | ENSG00000064012 | CASP8 | caspase 8, apoptosis-related cysteine peptidase |
| 1401 | NA | 1401 | ENSG00000132693 | CRP | C-reactive protein, pentraxin-related |
| 5159 | NA | 5159 | ENSG00000113721 | PDGFRB | platelet-derived growth factor receptor, beta polypeptide |
| 468 | NA | 468 | ENSG00000128272 | ATF4 | activating transcription factor 4 (tax-responsive enhancer element B67) |
| 207 | NA | 207 | ENSG00000142208 | AKT1 | v-akt murine thymoma viral oncogene homolog 1 |
| 4093 | NA | 4093 | ENSG00000120693 | SMAD9 | SMAD family member 9 |
| 5468 | NA | 5468 | ENSG00000132170 | PPARG | peroxisome proliferator-activated receptor gamma |
| 842 | NA | 842 | ENSG00000132906 | CASP9 | caspase 9, apoptosis-related cysteine peptidase |
| 4035 | NA | 4035 | ENSG00000123384 | LRP1 | low density lipoprotein receptor-related protein 1 |
| 4312 | NA | 4312 | ENSG00000196611 | MMP1 | matrix metallopeptidase 1 (interstitial collagenase) |
| 4773 | NA | 4773 | ENSG00000101096 | NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 |
| 857 | NA | 857 | ENSG00000105974 | CAV1 | caveolin 1, caveolae protein, 22kDa |
| 7422 | NA | 7422 | ENSG00000112715 | VEGFA | vascular endothelial growth factor A |
| 4088 | NA | 4088 | ENSG00000166949 | SMAD3 | SMAD family member 3 |
| 1907 | NA | 1907 | ENSG00000127129 | EDN2 | endothelin 2 |
| 5743 | NA | 5743 | ENSG00000073756 | PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
| 4087 | NA | 4087 | ENSG00000175387 | SMAD2 | SMAD family member 2 |
| 4314 | NA | 4314 | ENSG00000149968 | MMP3 | matrix metallopeptidase 3 (stromelysin 1, progelatinase) |
| 6772 | NA | 6772 | ENSG00000115415 | STAT1 | signal transducer and activator of transcription 1, 91kDa |
| 3065 | NA | 3065 | ENSG00000116478 | HDAC1 | histone deacetylase 1 |
| 3082 | NA | 3082 | ENSG00000019991 | HGF | hepatocyte growth factor (hepapoietin A; scatter factor) |
| 22926 | NA | 22926 | ENSG00000118217 | ATF6 | activating transcription factor 6 |
| 7412 | NA | 7412 | ENSG00000162692 | VCAM1 | vascular cell adhesion molecule 1 |
| 5054 | NA | 5054 | ENSG00000106366 | SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 |
| 657 | NA | 657 | ENSG00000107779 | BMPR1A | bone morphogenetic protein receptor, type IA |
| 7054 | NA | 7054 | ENSG00000180176 | TH | tyrosine hydroxylase |
| 6093 | NA | 6093 | ENSG00000067900 | ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 |
| 4086 | NA | 4086 | ENSG00000170365 | SMAD1 | SMAD family member 1 |
| 10891 | NA | 10891 | ENSG00000109819 | PPARGC1A | peroxisome proliferator-activated receptor gamma, coactivator 1 alpha |
| 5594 | NA | 5594 | ENSG00000100030 | MAPK1 | mitogen-activated protein kinase 1 |
| 57154 | NA | 57154 | ENSG00000198742 | SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 |
| 4089 | NA | 4089 | ENSG00000141646 | SMAD4 | SMAD family member 4 |
| 3598 | NA | 3598 | ENSG00000123496 | IL13RA2 | interleukin 13 receptor, alpha 2 |
| 658 | NA | 658 | ENSG00000138696 | BMPR1B | bone morphogenetic protein receptor, type IB |
| 4318 | NA | 4318 | ENSG00000100985 | MMP9 | matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) |
| 7433 | NA | 7433 | ENSG00000114812 | VIPR1 | vasoactive intestinal peptide receptor 1 |
| 659 | NA | 659 | ENSG00000204217 | BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) |
| 2335 | NA | 2335 | ENSG00000115414 | FN1 | fibronectin 1 |
| 4092 | NA | 4092 | ENSG00000101665 | SMAD7 | SMAD family member 7 |
| 3398 | NA | 3398 | ENSG00000115738 | ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein |
| 7046 | NA | 7046 | ENSG00000106799 | TGFBR1 | transforming growth factor, beta receptor 1 |
| 9518 | NA | 9518 | ENSG00000130513 | GDF15 | growth differentiation factor 15 |
| 7048 | NA | 7048 | ENSG00000163513 | TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) |
| 4485 | NA | 4485 | ENSG00000173531 | MST1 | macrophage stimulating 1 (hepatocyte growth factor-like) |
| 6714 | NA | 6714 | ENSG00000197122 | SRC | v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) |
| 3383 | NA | 3383 | ENSG00000090339 | ICAM1 | intercellular adhesion molecule 1 |
| 650 | NA | 650 | ENSG00000125845 | BMP2 | bone morphogenetic protein 2 |
| 3662 | NA | 3662 | ENSG00000137265 | IRF4 | interferon regulatory factor 4 |
| 6696 | NA | 6696 | ENSG00000118785 | SPP1 | secreted phosphoprotein 1 |
| 8600 | NA | 8600 | ENSG00000120659 | TNFSF11 | tumor necrosis factor (ligand) superfamily, member 11 |
| 4775 | NA | 4775 | ENSG00000072736 | NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 |
| 7076 | NA | 7076 | ENSG00000102265 | TIMP1 | TIMP metallopeptidase inhibitor 1 |
| 3480 | NA | 3480 | ENSG00000140443 | IGF1R | insulin-like growth factor 1 receptor |
| 57060 | NA | 57060 | ENSG00000090097 | PCBP4 | poly(rC) binding protein 4 |
| 4313 | NA | 4313 | ENSG00000087245 | MMP2 | matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) |
| 5592 | NA | 5592 | ENSG00000185532 | PRKG1 | protein kinase, cGMP-dependent, type I |
| 3952 | NA | 3952 | ENSG00000174697 | LEP | leptin |
| 1910 | NA | 1910 | ENSG00000136160 | EDNRB | endothelin receptor type B |
| 6387 | NA | 6387 | ENSG00000107562 | CXCL12 | chemokine (C-X-C motif) ligand 12 |
| 5292 | NA | 5292 | ENSG00000137193 | PIM1 | pim-1 oncogene |
| 6774 | NA | 6774 | ENSG00000168610 | STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) |
| 5551 | NA | 5551 | ENSG00000180644 | PRF1 | perforin 1 (pore forming protein) |
| 9475 | NA | 9475 | ENSG00000134318 | ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 |
| 1843 | NA | 1843 | ENSG00000120129 | DUSP1 | dual specificity phosphatase 1 |
| 4846 | NA | 4846 | ENSG00000164867 | NOS3 | nitric oxide synthase 3 (endothelial cell) |
| 7040 | NA | 7040 | ENSG00000105329 | TGFB1 | transforming growth factor, beta 1 |
| 7124 | NA | 7124 | ENSG00000232810 | TNF | tumor necrosis factor |
| 993 | NA | 993 | ENSG00000164045 | CDC25A | cell division cycle 25 homolog A (S. pombe) |
| 26585 | NA | 26585 | ENSG00000166923 | GREM1 | gremlin 1 |
| 387 | NA | 387 | ENSG00000067560 | RHOA | ras homolog family member A |
| 5617 | NA | 5617 | ENSG00000172179 | PRL | prolactin |
| 1906 | NA | 1906 | ENSG00000078401 | EDN1 | endothelin 1 |
| 2353 | NA | 2353 | ENSG00000170345 | FOS | FBJ murine osteosarcoma viral oncogene homolog |
| 1956 | NA | 1956 | ENSG00000146648 | EGFR | epidermal growth factor receptor |
| 1051 | NA | 1051 | ENSG00000172216 | CEBPB | CCAAT/enhancer binding protein (C/EBP), beta |
| 185 | NA | 185 | ENSG00000144891 | AGTR1 | angiotensin II receptor, type 1 |
| 3091 | NA | 3091 | ENSG00000100644 | HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) |
| 3569 | NA | 3569 | ENSG00000136244 | IL6 | interleukin 6 (interferon, beta 2) |
| 3099 | NA | 3099 | ENSG00000159399 | HK2 | hexokinase 2 |
| 652 | NA | 652 | ENSG00000125378 | BMP4 | bone morphogenetic protein 4 |
| 2099 | NA | 2099 | ENSG00000091831 | ESR1 | estrogen receptor 1 |
| 4843 | NA | 4843 | ENSG00000007171 | NOS2 | nitric oxide synthase 2, inducible |
| Pathway Commons pathway----Proteoglycan syndecan-mediated signaling events----DB_ID:1637 | |||||
| C=1345;O=110;E=10.63;R=10.34;rawP=1.95e-79;adjP=1.18e-77 | |||||
| 6347 | NA | 6347 | ENSG00000108691 | CCL2 | chemokine (C-C motif) ligand 2 |
| 959 | NA | 959 | ENSG00000102245 | CD40LG | CD40 ligand |
| 3791 | NA | 3791 | ENSG00000128052 | KDR | kinase insert domain receptor (a type III receptor tyrosine kinase) |
| 5037 | NA | 5037 | ENSG00000089220 | PEBP1 | phosphatidylethanolamine binding protein 1 |
| 1950 | NA | 1950 | ENSG00000138798 | EGF | epidermal growth factor |
| 3596 | NA | 3596 | ENSG00000169194 | IL13 | interleukin 13 |
| 6648 | NA | 6648 | ENSG00000112096 | SOD2 | superoxide dismutase 2, mitochondrial |
| 7157 | NA | 7157 | ENSG00000141510 | TP53 | tumor protein p53 |
| 331 | NA | 331 | ENSG00000101966 | XIAP | X-linked inhibitor of apoptosis |
| 4090 | NA | 4090 | ENSG00000113658 | SMAD5 | SMAD family member 5 |
| 2355 | NA | 2355 | ENSG00000075426 | FOSL2 | FOS-like antigen 2 |
| 5578 | NA | 5578 | ENSG00000154229 | PRKCA | protein kinase C, alpha |
| 3162 | NA | 3162 | ENSG00000100292 | HMOX1 | heme oxygenase (decycling) 1 |
| 5156 | NA | 5156 | ENSG00000134853 | PDGFRA | platelet-derived growth factor receptor, alpha polypeptide |
| 5566 | NA | 5566 | ENSG00000072062 | PRKACA | protein kinase, cAMP-dependent, catalytic, alpha |
| 5155 | NA | 5155 | ENSG00000100311 | PDGFB | platelet-derived growth factor beta polypeptide |
| 3371 | NA | 3371 | ENSG00000041982 | TNC | tenascin C |
| 7474 | NA | 7474 | ENSG00000114251 | WNT5A | wingless-type MMTV integration site family, member 5A |
| 2022 | NA | 2022 | ENSG00000106991 | ENG | endoglin |
| 595 | NA | 595 | ENSG00000110092 | CCND1 | cyclin D1 |
| 10746 | NA | 10746 | ENSG00000169967 | MAP3K2 | mitogen-activated protein kinase kinase kinase 2 |
| 7049 | NA | 7049 | ENSG00000069702 | TGFBR3 | transforming growth factor, beta receptor III |
| 114907 | NA | 114907 | ENSG00000156804 | FBXO32 | F-box protein 32 |
| 1499 | NA | 1499 | ENSG00000168036 | CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa |
| 1490 | NA | 1490 | ENSG00000118523 | CTGF | connective tissue growth factor |
| 1027 | NA | 1027 | ENSG00000111276 | CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) |
| 4791 | NA | 4791 | ENSG00000077150 | NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) |
| 841 | NA | 841 | ENSG00000064012 | CASP8 | caspase 8, apoptosis-related cysteine peptidase |
| 1401 | NA | 1401 | ENSG00000132693 | CRP | C-reactive protein, pentraxin-related |
| 5159 | NA | 5159 | ENSG00000113721 | PDGFRB | platelet-derived growth factor receptor, beta polypeptide |
| 468 | NA | 468 | ENSG00000128272 | ATF4 | activating transcription factor 4 (tax-responsive enhancer element B67) |
| 207 | NA | 207 | ENSG00000142208 | AKT1 | v-akt murine thymoma viral oncogene homolog 1 |
| 4093 | NA | 4093 | ENSG00000120693 | SMAD9 | SMAD family member 9 |
| 5468 | NA | 5468 | ENSG00000132170 | PPARG | peroxisome proliferator-activated receptor gamma |
| 842 | NA | 842 | ENSG00000132906 | CASP9 | caspase 9, apoptosis-related cysteine peptidase |
| 4035 | NA | 4035 | ENSG00000123384 | LRP1 | low density lipoprotein receptor-related protein 1 |
| 4312 | NA | 4312 | ENSG00000196611 | MMP1 | matrix metallopeptidase 1 (interstitial collagenase) |
| 4773 | NA | 4773 | ENSG00000101096 | NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 |
| 857 | NA | 857 | ENSG00000105974 | CAV1 | caveolin 1, caveolae protein, 22kDa |
| 7422 | NA | 7422 | ENSG00000112715 | VEGFA | vascular endothelial growth factor A |
| 4088 | NA | 4088 | ENSG00000166949 | SMAD3 | SMAD family member 3 |
| 1907 | NA | 1907 | ENSG00000127129 | EDN2 | endothelin 2 |
| 5743 | NA | 5743 | ENSG00000073756 | PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
| 4087 | NA | 4087 | ENSG00000175387 | SMAD2 | SMAD family member 2 |
| 4314 | NA | 4314 | ENSG00000149968 | MMP3 | matrix metallopeptidase 3 (stromelysin 1, progelatinase) |
| 6772 | NA | 6772 | ENSG00000115415 | STAT1 | signal transducer and activator of transcription 1, 91kDa |
| 3065 | NA | 3065 | ENSG00000116478 | HDAC1 | histone deacetylase 1 |
| 3082 | NA | 3082 | ENSG00000019991 | HGF | hepatocyte growth factor (hepapoietin A; scatter factor) |
| 22926 | NA | 22926 | ENSG00000118217 | ATF6 | activating transcription factor 6 |
| 5054 | NA | 5054 | ENSG00000106366 | SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 |
| 657 | NA | 657 | ENSG00000107779 | BMPR1A | bone morphogenetic protein receptor, type IA |
| 7054 | NA | 7054 | ENSG00000180176 | TH | tyrosine hydroxylase |
| 6093 | NA | 6093 | ENSG00000067900 | ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 |
| 4086 | NA | 4086 | ENSG00000170365 | SMAD1 | SMAD family member 1 |
| 10891 | NA | 10891 | ENSG00000109819 | PPARGC1A | peroxisome proliferator-activated receptor gamma, coactivator 1 alpha |
| 5594 | NA | 5594 | ENSG00000100030 | MAPK1 | mitogen-activated protein kinase 1 |
| 57154 | NA | 57154 | ENSG00000198742 | SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 |
| 4089 | NA | 4089 | ENSG00000141646 | SMAD4 | SMAD family member 4 |
| 3598 | NA | 3598 | ENSG00000123496 | IL13RA2 | interleukin 13 receptor, alpha 2 |
| 658 | NA | 658 | ENSG00000138696 | BMPR1B | bone morphogenetic protein receptor, type IB |
| 4318 | NA | 4318 | ENSG00000100985 | MMP9 | matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) |
| 7433 | NA | 7433 | ENSG00000114812 | VIPR1 | vasoactive intestinal peptide receptor 1 |
| 659 | NA | 659 | ENSG00000204217 | BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) |
| 2335 | NA | 2335 | ENSG00000115414 | FN1 | fibronectin 1 |
| 4092 | NA | 4092 | ENSG00000101665 | SMAD7 | SMAD family member 7 |
| 3398 | NA | 3398 | ENSG00000115738 | ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein |
| 7046 | NA | 7046 | ENSG00000106799 | TGFBR1 | transforming growth factor, beta receptor 1 |
| 9518 | NA | 9518 | ENSG00000130513 | GDF15 | growth differentiation factor 15 |
| 7048 | NA | 7048 | ENSG00000163513 | TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) |
| 4485 | NA | 4485 | ENSG00000173531 | MST1 | macrophage stimulating 1 (hepatocyte growth factor-like) |
| 6714 | NA | 6714 | ENSG00000197122 | SRC | v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) |
| 3383 | NA | 3383 | ENSG00000090339 | ICAM1 | intercellular adhesion molecule 1 |
| 7057 | NA | 7057 | ENSG00000137801 | THBS1 | thrombospondin 1 |
| 650 | NA | 650 | ENSG00000125845 | BMP2 | bone morphogenetic protein 2 |
| 3662 | NA | 3662 | ENSG00000137265 | IRF4 | interferon regulatory factor 4 |
| 6696 | NA | 6696 | ENSG00000118785 | SPP1 | secreted phosphoprotein 1 |
| 8600 | NA | 8600 | ENSG00000120659 | TNFSF11 | tumor necrosis factor (ligand) superfamily, member 11 |
| 4775 | NA | 4775 | ENSG00000072736 | NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 |
| 7076 | NA | 7076 | ENSG00000102265 | TIMP1 | TIMP metallopeptidase inhibitor 1 |
| 3480 | NA | 3480 | ENSG00000140443 | IGF1R | insulin-like growth factor 1 receptor |
| 57060 | NA | 57060 | ENSG00000090097 | PCBP4 | poly(rC) binding protein 4 |
| 4313 | NA | 4313 | ENSG00000087245 | MMP2 | matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) |
| 5592 | NA | 5592 | ENSG00000185532 | PRKG1 | protein kinase, cGMP-dependent, type I |
| 3952 | NA | 3952 | ENSG00000174697 | LEP | leptin |
| 1910 | NA | 1910 | ENSG00000136160 | EDNRB | endothelin receptor type B |
| 6387 | NA | 6387 | ENSG00000107562 | CXCL12 | chemokine (C-X-C motif) ligand 12 |
| 5292 | NA | 5292 | ENSG00000137193 | PIM1 | pim-1 oncogene |
| 6774 | NA | 6774 | ENSG00000168610 | STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) |
| 5551 | NA | 5551 | ENSG00000180644 | PRF1 | perforin 1 (pore forming protein) |
| 9475 | NA | 9475 | ENSG00000134318 | ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 |
| 1843 | NA | 1843 | ENSG00000120129 | DUSP1 | dual specificity phosphatase 1 |
| 4846 | NA | 4846 | ENSG00000164867 | NOS3 | nitric oxide synthase 3 (endothelial cell) |
| 7040 | NA | 7040 | ENSG00000105329 | TGFB1 | transforming growth factor, beta 1 |
| 7124 | NA | 7124 | ENSG00000232810 | TNF | tumor necrosis factor |
| 993 | NA | 993 | ENSG00000164045 | CDC25A | cell division cycle 25 homolog A (S. pombe) |
| 26585 | NA | 26585 | ENSG00000166923 | GREM1 | gremlin 1 |
| 387 | NA | 387 | ENSG00000067560 | RHOA | ras homolog family member A |
| 5617 | NA | 5617 | ENSG00000172179 | PRL | prolactin |
| 1906 | NA | 1906 | ENSG00000078401 | EDN1 | endothelin 1 |
| 10399 | NA | 10399 | ENSG00000204628 | GNB2L1 | guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 |
| 2353 | NA | 2353 | ENSG00000170345 | FOS | FBJ murine osteosarcoma viral oncogene homolog |
| 1956 | NA | 1956 | ENSG00000146648 | EGFR | epidermal growth factor receptor |
| 1051 | NA | 1051 | ENSG00000172216 | CEBPB | CCAAT/enhancer binding protein (C/EBP), beta |
| 185 | NA | 185 | ENSG00000144891 | AGTR1 | angiotensin II receptor, type 1 |
| 3091 | NA | 3091 | ENSG00000100644 | HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) |
| 3569 | NA | 3569 | ENSG00000136244 | IL6 | interleukin 6 (interferon, beta 2) |
| 3099 | NA | 3099 | ENSG00000159399 | HK2 | hexokinase 2 |
| 652 | NA | 652 | ENSG00000125378 | BMP4 | bone morphogenetic protein 4 |
| 2099 | NA | 2099 | ENSG00000091831 | ESR1 | estrogen receptor 1 |
| 4843 | NA | 4843 | ENSG00000007171 | NOS2 | nitric oxide synthase 2, inducible |
| Pathway Commons pathway----EGFR-dependent Endothelin signaling events----DB_ID:1603 | |||||
| C=1289;O=108;E=10.19;R=10.60;rawP=5.55e-79;adjP=2.93e-77 | |||||
| 6347 | NA | 6347 | ENSG00000108691 | CCL2 | chemokine (C-C motif) ligand 2 |
| 959 | NA | 959 | ENSG00000102245 | CD40LG | CD40 ligand |
| 3791 | NA | 3791 | ENSG00000128052 | KDR | kinase insert domain receptor (a type III receptor tyrosine kinase) |
| 5037 | NA | 5037 | ENSG00000089220 | PEBP1 | phosphatidylethanolamine binding protein 1 |
| 1950 | NA | 1950 | ENSG00000138798 | EGF | epidermal growth factor |
| 3596 | NA | 3596 | ENSG00000169194 | IL13 | interleukin 13 |
| 6648 | NA | 6648 | ENSG00000112096 | SOD2 | superoxide dismutase 2, mitochondrial |
| 7157 | NA | 7157 | ENSG00000141510 | TP53 | tumor protein p53 |
| 331 | NA | 331 | ENSG00000101966 | XIAP | X-linked inhibitor of apoptosis |
| 4090 | NA | 4090 | ENSG00000113658 | SMAD5 | SMAD family member 5 |
| 2355 | NA | 2355 | ENSG00000075426 | FOSL2 | FOS-like antigen 2 |
| 5578 | NA | 5578 | ENSG00000154229 | PRKCA | protein kinase C, alpha |
| 3162 | NA | 3162 | ENSG00000100292 | HMOX1 | heme oxygenase (decycling) 1 |
| 5156 | NA | 5156 | ENSG00000134853 | PDGFRA | platelet-derived growth factor receptor, alpha polypeptide |
| 5566 | NA | 5566 | ENSG00000072062 | PRKACA | protein kinase, cAMP-dependent, catalytic, alpha |
| 5155 | NA | 5155 | ENSG00000100311 | PDGFB | platelet-derived growth factor beta polypeptide |
| 7474 | NA | 7474 | ENSG00000114251 | WNT5A | wingless-type MMTV integration site family, member 5A |
| 2022 | NA | 2022 | ENSG00000106991 | ENG | endoglin |
| 595 | NA | 595 | ENSG00000110092 | CCND1 | cyclin D1 |
| 10746 | NA | 10746 | ENSG00000169967 | MAP3K2 | mitogen-activated protein kinase kinase kinase 2 |
| 7049 | NA | 7049 | ENSG00000069702 | TGFBR3 | transforming growth factor, beta receptor III |
| 114907 | NA | 114907 | ENSG00000156804 | FBXO32 | F-box protein 32 |
| 1499 | NA | 1499 | ENSG00000168036 | CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa |
| 1490 | NA | 1490 | ENSG00000118523 | CTGF | connective tissue growth factor |
| 1027 | NA | 1027 | ENSG00000111276 | CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) |
| 4791 | NA | 4791 | ENSG00000077150 | NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) |
| 841 | NA | 841 | ENSG00000064012 | CASP8 | caspase 8, apoptosis-related cysteine peptidase |
| 1401 | NA | 1401 | ENSG00000132693 | CRP | C-reactive protein, pentraxin-related |
| 5159 | NA | 5159 | ENSG00000113721 | PDGFRB | platelet-derived growth factor receptor, beta polypeptide |
| 468 | NA | 468 | ENSG00000128272 | ATF4 | activating transcription factor 4 (tax-responsive enhancer element B67) |
| 207 | NA | 207 | ENSG00000142208 | AKT1 | v-akt murine thymoma viral oncogene homolog 1 |
| 4093 | NA | 4093 | ENSG00000120693 | SMAD9 | SMAD family member 9 |
| 5468 | NA | 5468 | ENSG00000132170 | PPARG | peroxisome proliferator-activated receptor gamma |
| 842 | NA | 842 | ENSG00000132906 | CASP9 | caspase 9, apoptosis-related cysteine peptidase |
| 4035 | NA | 4035 | ENSG00000123384 | LRP1 | low density lipoprotein receptor-related protein 1 |
| 4312 | NA | 4312 | ENSG00000196611 | MMP1 | matrix metallopeptidase 1 (interstitial collagenase) |
| 4773 | NA | 4773 | ENSG00000101096 | NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 |
| 857 | NA | 857 | ENSG00000105974 | CAV1 | caveolin 1, caveolae protein, 22kDa |
| 7422 | NA | 7422 | ENSG00000112715 | VEGFA | vascular endothelial growth factor A |
| 1909 | NA | 1909 | ENSG00000151617 | EDNRA | endothelin receptor type A |
| 4088 | NA | 4088 | ENSG00000166949 | SMAD3 | SMAD family member 3 |
| 1907 | NA | 1907 | ENSG00000127129 | EDN2 | endothelin 2 |
| 5743 | NA | 5743 | ENSG00000073756 | PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
| 4087 | NA | 4087 | ENSG00000175387 | SMAD2 | SMAD family member 2 |
| 4314 | NA | 4314 | ENSG00000149968 | MMP3 | matrix metallopeptidase 3 (stromelysin 1, progelatinase) |
| 6772 | NA | 6772 | ENSG00000115415 | STAT1 | signal transducer and activator of transcription 1, 91kDa |
| 3065 | NA | 3065 | ENSG00000116478 | HDAC1 | histone deacetylase 1 |
| 3082 | NA | 3082 | ENSG00000019991 | HGF | hepatocyte growth factor (hepapoietin A; scatter factor) |
| 22926 | NA | 22926 | ENSG00000118217 | ATF6 | activating transcription factor 6 |
| 5054 | NA | 5054 | ENSG00000106366 | SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 |
| 657 | NA | 657 | ENSG00000107779 | BMPR1A | bone morphogenetic protein receptor, type IA |
| 7054 | NA | 7054 | ENSG00000180176 | TH | tyrosine hydroxylase |
| 6093 | NA | 6093 | ENSG00000067900 | ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 |
| 4086 | NA | 4086 | ENSG00000170365 | SMAD1 | SMAD family member 1 |
| 10891 | NA | 10891 | ENSG00000109819 | PPARGC1A | peroxisome proliferator-activated receptor gamma, coactivator 1 alpha |
| 5594 | NA | 5594 | ENSG00000100030 | MAPK1 | mitogen-activated protein kinase 1 |
| 57154 | NA | 57154 | ENSG00000198742 | SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 |
| 4089 | NA | 4089 | ENSG00000141646 | SMAD4 | SMAD family member 4 |
| 3598 | NA | 3598 | ENSG00000123496 | IL13RA2 | interleukin 13 receptor, alpha 2 |
| 658 | NA | 658 | ENSG00000138696 | BMPR1B | bone morphogenetic protein receptor, type IB |
| 4318 | NA | 4318 | ENSG00000100985 | MMP9 | matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) |
| 7433 | NA | 7433 | ENSG00000114812 | VIPR1 | vasoactive intestinal peptide receptor 1 |
| 659 | NA | 659 | ENSG00000204217 | BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) |
| 2335 | NA | 2335 | ENSG00000115414 | FN1 | fibronectin 1 |
| 4092 | NA | 4092 | ENSG00000101665 | SMAD7 | SMAD family member 7 |
| 3398 | NA | 3398 | ENSG00000115738 | ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein |
| 7046 | NA | 7046 | ENSG00000106799 | TGFBR1 | transforming growth factor, beta receptor 1 |
| 9518 | NA | 9518 | ENSG00000130513 | GDF15 | growth differentiation factor 15 |
| 7048 | NA | 7048 | ENSG00000163513 | TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) |
| 4485 | NA | 4485 | ENSG00000173531 | MST1 | macrophage stimulating 1 (hepatocyte growth factor-like) |
| 6714 | NA | 6714 | ENSG00000197122 | SRC | v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) |
| 3383 | NA | 3383 | ENSG00000090339 | ICAM1 | intercellular adhesion molecule 1 |
| 650 | NA | 650 | ENSG00000125845 | BMP2 | bone morphogenetic protein 2 |
| 3662 | NA | 3662 | ENSG00000137265 | IRF4 | interferon regulatory factor 4 |
| 6696 | NA | 6696 | ENSG00000118785 | SPP1 | secreted phosphoprotein 1 |
| 8600 | NA | 8600 | ENSG00000120659 | TNFSF11 | tumor necrosis factor (ligand) superfamily, member 11 |
| 4775 | NA | 4775 | ENSG00000072736 | NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 |
| 7076 | NA | 7076 | ENSG00000102265 | TIMP1 | TIMP metallopeptidase inhibitor 1 |
| 3480 | NA | 3480 | ENSG00000140443 | IGF1R | insulin-like growth factor 1 receptor |
| 57060 | NA | 57060 | ENSG00000090097 | PCBP4 | poly(rC) binding protein 4 |
| 4313 | NA | 4313 | ENSG00000087245 | MMP2 | matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) |
| 5592 | NA | 5592 | ENSG00000185532 | PRKG1 | protein kinase, cGMP-dependent, type I |
| 3952 | NA | 3952 | ENSG00000174697 | LEP | leptin |
| 1910 | NA | 1910 | ENSG00000136160 | EDNRB | endothelin receptor type B |
| 6387 | NA | 6387 | ENSG00000107562 | CXCL12 | chemokine (C-X-C motif) ligand 12 |
| 5292 | NA | 5292 | ENSG00000137193 | PIM1 | pim-1 oncogene |
| 6774 | NA | 6774 | ENSG00000168610 | STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) |
| 5551 | NA | 5551 | ENSG00000180644 | PRF1 | perforin 1 (pore forming protein) |
| 9475 | NA | 9475 | ENSG00000134318 | ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 |
| 1843 | NA | 1843 | ENSG00000120129 | DUSP1 | dual specificity phosphatase 1 |
| 4846 | NA | 4846 | ENSG00000164867 | NOS3 | nitric oxide synthase 3 (endothelial cell) |
| 7040 | NA | 7040 | ENSG00000105329 | TGFB1 | transforming growth factor, beta 1 |
| 7124 | NA | 7124 | ENSG00000232810 | TNF | tumor necrosis factor |
| 993 | NA | 993 | ENSG00000164045 | CDC25A | cell division cycle 25 homolog A (S. pombe) |
| 26585 | NA | 26585 | ENSG00000166923 | GREM1 | gremlin 1 |
| 387 | NA | 387 | ENSG00000067560 | RHOA | ras homolog family member A |
| 5617 | NA | 5617 | ENSG00000172179 | PRL | prolactin |
| 1906 | NA | 1906 | ENSG00000078401 | EDN1 | endothelin 1 |
| 2353 | NA | 2353 | ENSG00000170345 | FOS | FBJ murine osteosarcoma viral oncogene homolog |
| 1956 | NA | 1956 | ENSG00000146648 | EGFR | epidermal growth factor receptor |
| 1051 | NA | 1051 | ENSG00000172216 | CEBPB | CCAAT/enhancer binding protein (C/EBP), beta |
| 185 | NA | 185 | ENSG00000144891 | AGTR1 | angiotensin II receptor, type 1 |
| 3091 | NA | 3091 | ENSG00000100644 | HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) |
| 3569 | NA | 3569 | ENSG00000136244 | IL6 | interleukin 6 (interferon, beta 2) |
| 3099 | NA | 3099 | ENSG00000159399 | HK2 | hexokinase 2 |
| 652 | NA | 652 | ENSG00000125378 | BMP4 | bone morphogenetic protein 4 |
| 2099 | NA | 2099 | ENSG00000091831 | ESR1 | estrogen receptor 1 |
| 4843 | NA | 4843 | ENSG00000007171 | NOS2 | nitric oxide synthase 2, inducible |
| Pathway Commons pathway----IGF1 pathway----DB_ID:1482 | |||||
| C=1291;O=108;E=10.21;R=10.58;rawP=6.53e-79;adjP=3.07e-77 | |||||
| 6347 | NA | 6347 | ENSG00000108691 | CCL2 | chemokine (C-C motif) ligand 2 |
| 959 | NA | 959 | ENSG00000102245 | CD40LG | CD40 ligand |
| 3791 | NA | 3791 | ENSG00000128052 | KDR | kinase insert domain receptor (a type III receptor tyrosine kinase) |
| 5037 | NA | 5037 | ENSG00000089220 | PEBP1 | phosphatidylethanolamine binding protein 1 |
| 1950 | NA | 1950 | ENSG00000138798 | EGF | epidermal growth factor |
| 3596 | NA | 3596 | ENSG00000169194 | IL13 | interleukin 13 |
| 6648 | NA | 6648 | ENSG00000112096 | SOD2 | superoxide dismutase 2, mitochondrial |
| 7157 | NA | 7157 | ENSG00000141510 | TP53 | tumor protein p53 |
| 331 | NA | 331 | ENSG00000101966 | XIAP | X-linked inhibitor of apoptosis |
| 4090 | NA | 4090 | ENSG00000113658 | SMAD5 | SMAD family member 5 |
| 2355 | NA | 2355 | ENSG00000075426 | FOSL2 | FOS-like antigen 2 |
| 5578 | NA | 5578 | ENSG00000154229 | PRKCA | protein kinase C, alpha |
| 3162 | NA | 3162 | ENSG00000100292 | HMOX1 | heme oxygenase (decycling) 1 |
| 5156 | NA | 5156 | ENSG00000134853 | PDGFRA | platelet-derived growth factor receptor, alpha polypeptide |
| 5566 | NA | 5566 | ENSG00000072062 | PRKACA | protein kinase, cAMP-dependent, catalytic, alpha |
| 5155 | NA | 5155 | ENSG00000100311 | PDGFB | platelet-derived growth factor beta polypeptide |
| 7474 | NA | 7474 | ENSG00000114251 | WNT5A | wingless-type MMTV integration site family, member 5A |
| 2022 | NA | 2022 | ENSG00000106991 | ENG | endoglin |
| 595 | NA | 595 | ENSG00000110092 | CCND1 | cyclin D1 |
| 10746 | NA | 10746 | ENSG00000169967 | MAP3K2 | mitogen-activated protein kinase kinase kinase 2 |
| 7049 | NA | 7049 | ENSG00000069702 | TGFBR3 | transforming growth factor, beta receptor III |
| 114907 | NA | 114907 | ENSG00000156804 | FBXO32 | F-box protein 32 |
| 1499 | NA | 1499 | ENSG00000168036 | CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa |
| 1490 | NA | 1490 | ENSG00000118523 | CTGF | connective tissue growth factor |
| 1027 | NA | 1027 | ENSG00000111276 | CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) |
| 4791 | NA | 4791 | ENSG00000077150 | NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) |
| 841 | NA | 841 | ENSG00000064012 | CASP8 | caspase 8, apoptosis-related cysteine peptidase |
| 1401 | NA | 1401 | ENSG00000132693 | CRP | C-reactive protein, pentraxin-related |
| 5159 | NA | 5159 | ENSG00000113721 | PDGFRB | platelet-derived growth factor receptor, beta polypeptide |
| 468 | NA | 468 | ENSG00000128272 | ATF4 | activating transcription factor 4 (tax-responsive enhancer element B67) |
| 207 | NA | 207 | ENSG00000142208 | AKT1 | v-akt murine thymoma viral oncogene homolog 1 |
| 4093 | NA | 4093 | ENSG00000120693 | SMAD9 | SMAD family member 9 |
| 5468 | NA | 5468 | ENSG00000132170 | PPARG | peroxisome proliferator-activated receptor gamma |
| 842 | NA | 842 | ENSG00000132906 | CASP9 | caspase 9, apoptosis-related cysteine peptidase |
| 4035 | NA | 4035 | ENSG00000123384 | LRP1 | low density lipoprotein receptor-related protein 1 |
| 4312 | NA | 4312 | ENSG00000196611 | MMP1 | matrix metallopeptidase 1 (interstitial collagenase) |
| 4773 | NA | 4773 | ENSG00000101096 | NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 |
| 857 | NA | 857 | ENSG00000105974 | CAV1 | caveolin 1, caveolae protein, 22kDa |
| 7422 | NA | 7422 | ENSG00000112715 | VEGFA | vascular endothelial growth factor A |
| 4088 | NA | 4088 | ENSG00000166949 | SMAD3 | SMAD family member 3 |
| 1907 | NA | 1907 | ENSG00000127129 | EDN2 | endothelin 2 |
| 5743 | NA | 5743 | ENSG00000073756 | PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
| 4087 | NA | 4087 | ENSG00000175387 | SMAD2 | SMAD family member 2 |
| 4314 | NA | 4314 | ENSG00000149968 | MMP3 | matrix metallopeptidase 3 (stromelysin 1, progelatinase) |
| 6772 | NA | 6772 | ENSG00000115415 | STAT1 | signal transducer and activator of transcription 1, 91kDa |
| 3065 | NA | 3065 | ENSG00000116478 | HDAC1 | histone deacetylase 1 |
| 3082 | NA | 3082 | ENSG00000019991 | HGF | hepatocyte growth factor (hepapoietin A; scatter factor) |
| 22926 | NA | 22926 | ENSG00000118217 | ATF6 | activating transcription factor 6 |
| 5054 | NA | 5054 | ENSG00000106366 | SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 |
| 657 | NA | 657 | ENSG00000107779 | BMPR1A | bone morphogenetic protein receptor, type IA |
| 7054 | NA | 7054 | ENSG00000180176 | TH | tyrosine hydroxylase |
| 6093 | NA | 6093 | ENSG00000067900 | ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 |
| 4086 | NA | 4086 | ENSG00000170365 | SMAD1 | SMAD family member 1 |
| 10891 | NA | 10891 | ENSG00000109819 | PPARGC1A | peroxisome proliferator-activated receptor gamma, coactivator 1 alpha |
| 5594 | NA | 5594 | ENSG00000100030 | MAPK1 | mitogen-activated protein kinase 1 |
| 57154 | NA | 57154 | ENSG00000198742 | SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 |
| 4089 | NA | 4089 | ENSG00000141646 | SMAD4 | SMAD family member 4 |
| 3598 | NA | 3598 | ENSG00000123496 | IL13RA2 | interleukin 13 receptor, alpha 2 |
| 658 | NA | 658 | ENSG00000138696 | BMPR1B | bone morphogenetic protein receptor, type IB |
| 4318 | NA | 4318 | ENSG00000100985 | MMP9 | matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) |
| 7433 | NA | 7433 | ENSG00000114812 | VIPR1 | vasoactive intestinal peptide receptor 1 |
| 659 | NA | 659 | ENSG00000204217 | BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) |
| 2335 | NA | 2335 | ENSG00000115414 | FN1 | fibronectin 1 |
| 4092 | NA | 4092 | ENSG00000101665 | SMAD7 | SMAD family member 7 |
| 3398 | NA | 3398 | ENSG00000115738 | ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein |
| 7046 | NA | 7046 | ENSG00000106799 | TGFBR1 | transforming growth factor, beta receptor 1 |
| 9518 | NA | 9518 | ENSG00000130513 | GDF15 | growth differentiation factor 15 |
| 7048 | NA | 7048 | ENSG00000163513 | TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) |
| 4485 | NA | 4485 | ENSG00000173531 | MST1 | macrophage stimulating 1 (hepatocyte growth factor-like) |
| 6714 | NA | 6714 | ENSG00000197122 | SRC | v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) |
| 3383 | NA | 3383 | ENSG00000090339 | ICAM1 | intercellular adhesion molecule 1 |
| 650 | NA | 650 | ENSG00000125845 | BMP2 | bone morphogenetic protein 2 |
| 3662 | NA | 3662 | ENSG00000137265 | IRF4 | interferon regulatory factor 4 |
| 6696 | NA | 6696 | ENSG00000118785 | SPP1 | secreted phosphoprotein 1 |
| 8600 | NA | 8600 | ENSG00000120659 | TNFSF11 | tumor necrosis factor (ligand) superfamily, member 11 |
| 4775 | NA | 4775 | ENSG00000072736 | NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 |
| 7076 | NA | 7076 | ENSG00000102265 | TIMP1 | TIMP metallopeptidase inhibitor 1 |
| 3480 | NA | 3480 | ENSG00000140443 | IGF1R | insulin-like growth factor 1 receptor |
| 57060 | NA | 57060 | ENSG00000090097 | PCBP4 | poly(rC) binding protein 4 |
| 4313 | NA | 4313 | ENSG00000087245 | MMP2 | matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) |
| 5592 | NA | 5592 | ENSG00000185532 | PRKG1 | protein kinase, cGMP-dependent, type I |
| 3952 | NA | 3952 | ENSG00000174697 | LEP | leptin |
| 1910 | NA | 1910 | ENSG00000136160 | EDNRB | endothelin receptor type B |
| 6387 | NA | 6387 | ENSG00000107562 | CXCL12 | chemokine (C-X-C motif) ligand 12 |
| 5292 | NA | 5292 | ENSG00000137193 | PIM1 | pim-1 oncogene |
| 6774 | NA | 6774 | ENSG00000168610 | STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) |
| 5551 | NA | 5551 | ENSG00000180644 | PRF1 | perforin 1 (pore forming protein) |
| 9475 | NA | 9475 | ENSG00000134318 | ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 |
| 1843 | NA | 1843 | ENSG00000120129 | DUSP1 | dual specificity phosphatase 1 |
| 4846 | NA | 4846 | ENSG00000164867 | NOS3 | nitric oxide synthase 3 (endothelial cell) |
| 7040 | NA | 7040 | ENSG00000105329 | TGFB1 | transforming growth factor, beta 1 |
| 7124 | NA | 7124 | ENSG00000232810 | TNF | tumor necrosis factor |
| 993 | NA | 993 | ENSG00000164045 | CDC25A | cell division cycle 25 homolog A (S. pombe) |
| 26585 | NA | 26585 | ENSG00000166923 | GREM1 | gremlin 1 |
| 387 | NA | 387 | ENSG00000067560 | RHOA | ras homolog family member A |
| 5617 | NA | 5617 | ENSG00000172179 | PRL | prolactin |
| 1906 | NA | 1906 | ENSG00000078401 | EDN1 | endothelin 1 |
| 10399 | NA | 10399 | ENSG00000204628 | GNB2L1 | guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 |
| 2353 | NA | 2353 | ENSG00000170345 | FOS | FBJ murine osteosarcoma viral oncogene homolog |
| 1956 | NA | 1956 | ENSG00000146648 | EGFR | epidermal growth factor receptor |
| 1051 | NA | 1051 | ENSG00000172216 | CEBPB | CCAAT/enhancer binding protein (C/EBP), beta |
| 185 | NA | 185 | ENSG00000144891 | AGTR1 | angiotensin II receptor, type 1 |
| 3091 | NA | 3091 | ENSG00000100644 | HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) |
| 3569 | NA | 3569 | ENSG00000136244 | IL6 | interleukin 6 (interferon, beta 2) |
| 3099 | NA | 3099 | ENSG00000159399 | HK2 | hexokinase 2 |
| 652 | NA | 652 | ENSG00000125378 | BMP4 | bone morphogenetic protein 4 |
| 2099 | NA | 2099 | ENSG00000091831 | ESR1 | estrogen receptor 1 |
| 4843 | NA | 4843 | ENSG00000007171 | NOS2 | nitric oxide synthase 2, inducible |
| Pathway Commons pathway----PDGF receptor signaling network----DB_ID:1497 | |||||
| C=1293;O=108;E=10.22;R=10.56;rawP=7.69e-79;adjP=3.25e-77 | |||||
| 6347 | NA | 6347 | ENSG00000108691 | CCL2 | chemokine (C-C motif) ligand 2 |
| 959 | NA | 959 | ENSG00000102245 | CD40LG | CD40 ligand |
| 3791 | NA | 3791 | ENSG00000128052 | KDR | kinase insert domain receptor (a type III receptor tyrosine kinase) |
| 5037 | NA | 5037 | ENSG00000089220 | PEBP1 | phosphatidylethanolamine binding protein 1 |
| 1950 | NA | 1950 | ENSG00000138798 | EGF | epidermal growth factor |
| 3596 | NA | 3596 | ENSG00000169194 | IL13 | interleukin 13 |
| 6648 | NA | 6648 | ENSG00000112096 | SOD2 | superoxide dismutase 2, mitochondrial |
| 7157 | NA | 7157 | ENSG00000141510 | TP53 | tumor protein p53 |
| 331 | NA | 331 | ENSG00000101966 | XIAP | X-linked inhibitor of apoptosis |
| 4090 | NA | 4090 | ENSG00000113658 | SMAD5 | SMAD family member 5 |
| 2355 | NA | 2355 | ENSG00000075426 | FOSL2 | FOS-like antigen 2 |
| 5578 | NA | 5578 | ENSG00000154229 | PRKCA | protein kinase C, alpha |
| 3162 | NA | 3162 | ENSG00000100292 | HMOX1 | heme oxygenase (decycling) 1 |
| 5156 | NA | 5156 | ENSG00000134853 | PDGFRA | platelet-derived growth factor receptor, alpha polypeptide |
| 5566 | NA | 5566 | ENSG00000072062 | PRKACA | protein kinase, cAMP-dependent, catalytic, alpha |
| 5155 | NA | 5155 | ENSG00000100311 | PDGFB | platelet-derived growth factor beta polypeptide |
| 7474 | NA | 7474 | ENSG00000114251 | WNT5A | wingless-type MMTV integration site family, member 5A |
| 5154 | NA | 5154 | ENSG00000197461 | PDGFA | platelet-derived growth factor alpha polypeptide |
| 2022 | NA | 2022 | ENSG00000106991 | ENG | endoglin |
| 595 | NA | 595 | ENSG00000110092 | CCND1 | cyclin D1 |
| 10746 | NA | 10746 | ENSG00000169967 | MAP3K2 | mitogen-activated protein kinase kinase kinase 2 |
| 7049 | NA | 7049 | ENSG00000069702 | TGFBR3 | transforming growth factor, beta receptor III |
| 114907 | NA | 114907 | ENSG00000156804 | FBXO32 | F-box protein 32 |
| 1499 | NA | 1499 | ENSG00000168036 | CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa |
| 1490 | NA | 1490 | ENSG00000118523 | CTGF | connective tissue growth factor |
| 1027 | NA | 1027 | ENSG00000111276 | CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) |
| 4791 | NA | 4791 | ENSG00000077150 | NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) |
| 841 | NA | 841 | ENSG00000064012 | CASP8 | caspase 8, apoptosis-related cysteine peptidase |
| 1401 | NA | 1401 | ENSG00000132693 | CRP | C-reactive protein, pentraxin-related |
| 5159 | NA | 5159 | ENSG00000113721 | PDGFRB | platelet-derived growth factor receptor, beta polypeptide |
| 468 | NA | 468 | ENSG00000128272 | ATF4 | activating transcription factor 4 (tax-responsive enhancer element B67) |
| 207 | NA | 207 | ENSG00000142208 | AKT1 | v-akt murine thymoma viral oncogene homolog 1 |
| 4093 | NA | 4093 | ENSG00000120693 | SMAD9 | SMAD family member 9 |
| 5468 | NA | 5468 | ENSG00000132170 | PPARG | peroxisome proliferator-activated receptor gamma |
| 842 | NA | 842 | ENSG00000132906 | CASP9 | caspase 9, apoptosis-related cysteine peptidase |
| 4035 | NA | 4035 | ENSG00000123384 | LRP1 | low density lipoprotein receptor-related protein 1 |
| 4312 | NA | 4312 | ENSG00000196611 | MMP1 | matrix metallopeptidase 1 (interstitial collagenase) |
| 4773 | NA | 4773 | ENSG00000101096 | NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 |
| 857 | NA | 857 | ENSG00000105974 | CAV1 | caveolin 1, caveolae protein, 22kDa |
| 7422 | NA | 7422 | ENSG00000112715 | VEGFA | vascular endothelial growth factor A |
| 4088 | NA | 4088 | ENSG00000166949 | SMAD3 | SMAD family member 3 |
| 1907 | NA | 1907 | ENSG00000127129 | EDN2 | endothelin 2 |
| 5743 | NA | 5743 | ENSG00000073756 | PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
| 4087 | NA | 4087 | ENSG00000175387 | SMAD2 | SMAD family member 2 |
| 4314 | NA | 4314 | ENSG00000149968 | MMP3 | matrix metallopeptidase 3 (stromelysin 1, progelatinase) |
| 6772 | NA | 6772 | ENSG00000115415 | STAT1 | signal transducer and activator of transcription 1, 91kDa |
| 3065 | NA | 3065 | ENSG00000116478 | HDAC1 | histone deacetylase 1 |
| 3082 | NA | 3082 | ENSG00000019991 | HGF | hepatocyte growth factor (hepapoietin A; scatter factor) |
| 22926 | NA | 22926 | ENSG00000118217 | ATF6 | activating transcription factor 6 |
| 5054 | NA | 5054 | ENSG00000106366 | SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 |
| 657 | NA | 657 | ENSG00000107779 | BMPR1A | bone morphogenetic protein receptor, type IA |
| 7054 | NA | 7054 | ENSG00000180176 | TH | tyrosine hydroxylase |
| 6093 | NA | 6093 | ENSG00000067900 | ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 |
| 4086 | NA | 4086 | ENSG00000170365 | SMAD1 | SMAD family member 1 |
| 10891 | NA | 10891 | ENSG00000109819 | PPARGC1A | peroxisome proliferator-activated receptor gamma, coactivator 1 alpha |
| 5594 | NA | 5594 | ENSG00000100030 | MAPK1 | mitogen-activated protein kinase 1 |
| 57154 | NA | 57154 | ENSG00000198742 | SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 |
| 4089 | NA | 4089 | ENSG00000141646 | SMAD4 | SMAD family member 4 |
| 3598 | NA | 3598 | ENSG00000123496 | IL13RA2 | interleukin 13 receptor, alpha 2 |
| 658 | NA | 658 | ENSG00000138696 | BMPR1B | bone morphogenetic protein receptor, type IB |
| 4318 | NA | 4318 | ENSG00000100985 | MMP9 | matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) |
| 7433 | NA | 7433 | ENSG00000114812 | VIPR1 | vasoactive intestinal peptide receptor 1 |
| 659 | NA | 659 | ENSG00000204217 | BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) |
| 2335 | NA | 2335 | ENSG00000115414 | FN1 | fibronectin 1 |
| 4092 | NA | 4092 | ENSG00000101665 | SMAD7 | SMAD family member 7 |
| 3398 | NA | 3398 | ENSG00000115738 | ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein |
| 7046 | NA | 7046 | ENSG00000106799 | TGFBR1 | transforming growth factor, beta receptor 1 |
| 9518 | NA | 9518 | ENSG00000130513 | GDF15 | growth differentiation factor 15 |
| 7048 | NA | 7048 | ENSG00000163513 | TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) |
| 4485 | NA | 4485 | ENSG00000173531 | MST1 | macrophage stimulating 1 (hepatocyte growth factor-like) |
| 6714 | NA | 6714 | ENSG00000197122 | SRC | v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) |
| 3383 | NA | 3383 | ENSG00000090339 | ICAM1 | intercellular adhesion molecule 1 |
| 650 | NA | 650 | ENSG00000125845 | BMP2 | bone morphogenetic protein 2 |
| 3662 | NA | 3662 | ENSG00000137265 | IRF4 | interferon regulatory factor 4 |
| 6696 | NA | 6696 | ENSG00000118785 | SPP1 | secreted phosphoprotein 1 |
| 8600 | NA | 8600 | ENSG00000120659 | TNFSF11 | tumor necrosis factor (ligand) superfamily, member 11 |
| 4775 | NA | 4775 | ENSG00000072736 | NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 |
| 7076 | NA | 7076 | ENSG00000102265 | TIMP1 | TIMP metallopeptidase inhibitor 1 |
| 3480 | NA | 3480 | ENSG00000140443 | IGF1R | insulin-like growth factor 1 receptor |
| 57060 | NA | 57060 | ENSG00000090097 | PCBP4 | poly(rC) binding protein 4 |
| 4313 | NA | 4313 | ENSG00000087245 | MMP2 | matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) |
| 5592 | NA | 5592 | ENSG00000185532 | PRKG1 | protein kinase, cGMP-dependent, type I |
| 3952 | NA | 3952 | ENSG00000174697 | LEP | leptin |
| 1910 | NA | 1910 | ENSG00000136160 | EDNRB | endothelin receptor type B |
| 6387 | NA | 6387 | ENSG00000107562 | CXCL12 | chemokine (C-X-C motif) ligand 12 |
| 5292 | NA | 5292 | ENSG00000137193 | PIM1 | pim-1 oncogene |
| 6774 | NA | 6774 | ENSG00000168610 | STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) |
| 5551 | NA | 5551 | ENSG00000180644 | PRF1 | perforin 1 (pore forming protein) |
| 9475 | NA | 9475 | ENSG00000134318 | ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 |
| 1843 | NA | 1843 | ENSG00000120129 | DUSP1 | dual specificity phosphatase 1 |
| 4846 | NA | 4846 | ENSG00000164867 | NOS3 | nitric oxide synthase 3 (endothelial cell) |
| 7040 | NA | 7040 | ENSG00000105329 | TGFB1 | transforming growth factor, beta 1 |
| 7124 | NA | 7124 | ENSG00000232810 | TNF | tumor necrosis factor |
| 993 | NA | 993 | ENSG00000164045 | CDC25A | cell division cycle 25 homolog A (S. pombe) |
| 26585 | NA | 26585 | ENSG00000166923 | GREM1 | gremlin 1 |
| 387 | NA | 387 | ENSG00000067560 | RHOA | ras homolog family member A |
| 5617 | NA | 5617 | ENSG00000172179 | PRL | prolactin |
| 1906 | NA | 1906 | ENSG00000078401 | EDN1 | endothelin 1 |
| 2353 | NA | 2353 | ENSG00000170345 | FOS | FBJ murine osteosarcoma viral oncogene homolog |
| 1956 | NA | 1956 | ENSG00000146648 | EGFR | epidermal growth factor receptor |
| 1051 | NA | 1051 | ENSG00000172216 | CEBPB | CCAAT/enhancer binding protein (C/EBP), beta |
| 185 | NA | 185 | ENSG00000144891 | AGTR1 | angiotensin II receptor, type 1 |
| 3091 | NA | 3091 | ENSG00000100644 | HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) |
| 3569 | NA | 3569 | ENSG00000136244 | IL6 | interleukin 6 (interferon, beta 2) |
| 3099 | NA | 3099 | ENSG00000159399 | HK2 | hexokinase 2 |
| 652 | NA | 652 | ENSG00000125378 | BMP4 | bone morphogenetic protein 4 |
| 2099 | NA | 2099 | ENSG00000091831 | ESR1 | estrogen receptor 1 |
| 4843 | NA | 4843 | ENSG00000007171 | NOS2 | nitric oxide synthase 2, inducible |