Pulmonary Arterial Hypertension KnowledgeBase (PAHKB)
PAHKB
Pulmonary Arterial Hypertension KnowledgeBase
Organism: Hsapiens, Id Type: entrezgene, Ref Set: entrezgene, Significance Level: Top10, Statistics Test: Hypergeometric, MTC: BH, Minimum: 2

The results for each enriched gene set are listed in this table. For each gene set, the first row lists the gene set name, and corresponding Gene Set ID. The second row lists number of reference genes in the category (C), number of genes in the gene set and also in the category (O), expected number in the category (E), Ratio of enrichment (R), p value from hypergeometric test (rawP), and p value adjusted by the multiple test adjustment (adjP). Finally, genes in the pathway are listed. For each gene, the table lists the user uploaded ID and value (optional), Entrez ID, Ensembl Gene Stable ID, Gene symbol, and description. Ensembl Gene Stable ID and Entrez Gene ID are linked to the Ensembl and Entrez Gene databases, respectively.
Transcription Target----hsa_TGGAAA_VNFAT_Q4_01----DB_ID:2437
C=1871;O=75;E=14.79;R=5.07;rawP=1.11e-31;adjP=6.01e-29
6347 NA 6347 ENSG00000108691 CCL2 chemokine (C-C motif) ligand 2
81839 NA 81839 ENSG00000173218 VANGL1 vang-like 1 (van gogh, Drosophila)
959 NA 959 ENSG00000102245 CD40LG CD40 ligand
5166 NA 5166 ENSG00000004799 PDK4 pyruvate dehydrogenase kinase, isozyme 4
1950 NA 1950 ENSG00000138798 EGF epidermal growth factor
3596 NA 3596 ENSG00000169194 IL13 interleukin 13
7157 NA 7157 ENSG00000141510 TP53 tumor protein p53
4090 NA 4090 ENSG00000113658 SMAD5 SMAD family member 5
5156 NA 5156 ENSG00000134853 PDGFRA platelet-derived growth factor receptor, alpha polypeptide
5566 NA 5566 ENSG00000072062 PRKACA protein kinase, cAMP-dependent, catalytic, alpha
5155 NA 5155 ENSG00000100311 PDGFB platelet-derived growth factor beta polypeptide
3037 NA 3037 ENSG00000170961 HAS2 hyaluronan synthase 2
4223 NA 4223 ENSG00000106511 MEOX2 mesenchyme homeobox 2
64881 NA 64881 ENSG00000197991 PCDH20 protocadherin 20
7474 NA 7474 ENSG00000114251 WNT5A wingless-type MMTV integration site family, member 5A
5164 NA 5164 ENSG00000005882 PDK2 pyruvate dehydrogenase kinase, isozyme 2
775 NA 775 ENSG00000151067 CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit
1490 NA 1490 ENSG00000118523 CTGF connective tissue growth factor
6863 NA 6863 ENSG00000006128 TAC1 tachykinin, precursor 1
4791 NA 4791 ENSG00000077150 NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
29843 NA 29843 ENSG00000079387 SENP1 SUMO1/sentrin specific peptidase 1
1849 NA 1849 ENSG00000164086 DUSP7 dual specificity phosphatase 7
8743 NA 8743 ENSG00000121858 TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
3741 NA 3741 ENSG00000130037 KCNA5 potassium voltage-gated channel, shaker-related subfamily, member 5
4773 NA 4773 ENSG00000101096 NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
6988 NA 6988 ENSG00000145022 TCTA T-cell leukemia translocation altered
7422 NA 7422 ENSG00000112715 VEGFA vascular endothelial growth factor A
51099 NA 51099 ENSG00000011198 ABHD5 abhydrolase domain containing 5
1909 NA 1909 ENSG00000151617 EDNRA endothelin receptor type A
4088 NA 4088 ENSG00000166949 SMAD3 SMAD family member 3
3627 NA 3627 ENSG00000169245 CXCL10 chemokine (C-X-C motif) ligand 10
4314 NA 4314 ENSG00000149968 MMP3 matrix metallopeptidase 3 (stromelysin 1, progelatinase)
2983 NA 2983 ENSG00000061918 GUCY1B3 guanylate cyclase 1, soluble, beta 3
3082 NA 3082 ENSG00000019991 HGF hepatocyte growth factor (hepapoietin A; scatter factor)
688 NA 688 ENSG00000102554 KLF5 Kruppel-like factor 5 (intestinal)
10891 NA 10891 ENSG00000109819 PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
284 NA 284 ENSG00000154188 ANGPT1 angiopoietin 1
2335 NA 2335 ENSG00000115414 FN1 fibronectin 1
659 NA 659 ENSG00000204217 BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase)
3398 NA 3398 ENSG00000115738 ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
4842 NA 4842 ENSG00000089250 NOS1 nitric oxide synthase 1 (neuronal)
6714 NA 6714 ENSG00000197122 SRC v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
3383 NA 3383 ENSG00000090339 ICAM1 intercellular adhesion molecule 1
650 NA 650 ENSG00000125845 BMP2 bone morphogenetic protein 2
6696 NA 6696 ENSG00000118785 SPP1 secreted phosphoprotein 1
3662 NA 3662 ENSG00000137265 IRF4 interferon regulatory factor 4
8600 NA 8600 ENSG00000120659 TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
3952 NA 3952 ENSG00000174697 LEP leptin
5292 NA 5292 ENSG00000137193 PIM1 pim-1 oncogene
30819 NA 30819 ENSG00000120049 KCNIP2 Kv channel interacting protein 2
5551 NA 5551 ENSG00000180644 PRF1 perforin 1 (pore forming protein)
6774 NA 6774 ENSG00000168610 STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
51144 NA 51144 ENSG00000149084 HSD17B12 hydroxysteroid (17-beta) dehydrogenase 12
3156 NA 3156 ENSG00000113161 HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
7124 NA 7124 ENSG00000232810 TNF tumor necrosis factor
7471 NA 7471 ENSG00000125084 WNT1 wingless-type MMTV integration site family, member 1
26585 NA 26585 ENSG00000166923 GREM1 gremlin 1
387 NA 387 ENSG00000067560 RHOA ras homolog family member A
2104 NA 2104 ENSG00000196482 ESRRG estrogen-related receptor gamma
9068 NA 9068 ENSG00000116194 ANGPTL1 angiopoietin-like 1
23365 NA 23365 ENSG00000196914 ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12
5165 NA 5165 ENSG00000067992 PDK3 pyruvate dehydrogenase kinase, isozyme 3
2353 NA 2353 ENSG00000170345 FOS FBJ murine osteosarcoma viral oncogene homolog
10425 NA 10425 ENSG00000177479 ARIH2 ariadne homolog 2 (Drosophila)
388 NA 388 ENSG00000143878 RHOB ras homolog family member B
8412 NA 8412 ENSG00000137936 BCAR3 breast cancer anti-estrogen resistance 3
2103 NA 2103 ENSG00000119715 ESRRB estrogen-related receptor beta
51554 NA 51554 ENSG00000129048 CCRL1 chemokine (C-C motif) receptor-like 1
3091 NA 3091 ENSG00000100644 HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
3569 NA 3569 ENSG00000136244 IL6 interleukin 6 (interferon, beta 2)
7494 NA 7494 ENSG00000100219 XBP1 X-box binding protein 1
2852 NA 2852 ENSG00000164850 GPER G protein-coupled estrogen receptor 1
652 NA 652 ENSG00000125378 BMP4 bone morphogenetic protein 4
59272 NA 59272 ENSG00000130234 ACE2 angiotensin I converting enzyme (peptidyl-dipeptidase A) 2
2099 NA 2099 ENSG00000091831 ESR1 estrogen receptor 1
Transcription Target----hsa_GGGAGGRR_VMAZ_Q6----DB_ID:2430
C=2250;O=69;E=17.79;R=3.88;rawP=2.12e-22;adjP=5.73e-20
7223 NA 7223 ENSG00000133107 TRPC4 transient receptor potential cation channel, subfamily C, member 4
3397 NA 3397 ENSG00000125968 ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
81839 NA 81839 ENSG00000173218 VANGL1 vang-like 1 (van gogh, Drosophila)
959 NA 959 ENSG00000102245 CD40LG CD40 ligand
3596 NA 3596 ENSG00000169194 IL13 interleukin 13
7157 NA 7157 ENSG00000141510 TP53 tumor protein p53
5460 NA 5460 ENSG00000204531 POU5F1 POU class 5 homeobox 1
5566 NA 5566 ENSG00000072062 PRKACA protein kinase, cAMP-dependent, catalytic, alpha
5155 NA 5155 ENSG00000100311 PDGFB platelet-derived growth factor beta polypeptide
64881 NA 64881 ENSG00000197991 PCDH20 protocadherin 20
7474 NA 7474 ENSG00000114251 WNT5A wingless-type MMTV integration site family, member 5A
595 NA 595 ENSG00000110092 CCND1 cyclin D1
5164 NA 5164 ENSG00000005882 PDK2 pyruvate dehydrogenase kinase, isozyme 2
775 NA 775 ENSG00000151067 CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit
1490 NA 1490 ENSG00000118523 CTGF connective tissue growth factor
4854 NA 4854 ENSG00000074181 NOTCH3 notch 3
6863 NA 6863 ENSG00000006128 TAC1 tachykinin, precursor 1
4791 NA 4791 ENSG00000077150 NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
29843 NA 29843 ENSG00000079387 SENP1 SUMO1/sentrin specific peptidase 1
1072 NA 1072 ENSG00000172757 CFL1 cofilin 1 (non-muscle)
1849 NA 1849 ENSG00000164086 DUSP7 dual specificity phosphatase 7
9166 NA 9166 ENSG00000147654 EBAG9 estrogen receptor binding site associated, antigen, 9
1394 NA 1394 ENSG00000120088 CRHR1 corticotropin releasing hormone receptor 1
5468 NA 5468 ENSG00000132170 PPARG peroxisome proliferator-activated receptor gamma
6275 NA 6275 ENSG00000196154 S100A4 S100 calcium binding protein A4
4035 NA 4035 ENSG00000123384 LRP1 low density lipoprotein receptor-related protein 1
3294 NA 3294 ENSG00000086696 HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2
6988 NA 6988 ENSG00000145022 TCTA T-cell leukemia translocation altered
7422 NA 7422 ENSG00000112715 VEGFA vascular endothelial growth factor A
51170 NA 51170 ENSG00000198189 HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
1907 NA 1907 ENSG00000127129 EDN2 endothelin 2
4134 NA 4134 ENSG00000047849 MAP4 microtubule-associated protein 4
147381 NA 147381 ENSG00000141668 CBLN2 cerebellin 2 precursor
3065 NA 3065 ENSG00000116478 HDAC1 histone deacetylase 1
6093 NA 6093 ENSG00000067900 ROCK1 Rho-associated, coiled-coil containing protein kinase 1
6331 NA 6331 ENSG00000183873 SCN5A sodium channel, voltage-gated, type V, alpha subunit
659 NA 659 ENSG00000204217 BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase)
1236 NA 1236 ENSG00000126353 CCR7 chemokine (C-C motif) receptor 7
9518 NA 9518 ENSG00000130513 GDF15 growth differentiation factor 15
4842 NA 4842 ENSG00000089250 NOS1 nitric oxide synthase 1 (neuronal)
3337 NA 3337 ENSG00000132002 DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
6714 NA 6714 ENSG00000197122 SRC v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
650 NA 650 ENSG00000125845 BMP2 bone morphogenetic protein 2
3480 NA 3480 ENSG00000140443 IGF1R insulin-like growth factor 1 receptor
57060 NA 57060 ENSG00000090097 PCBP4 poly(rC) binding protein 4
4313 NA 4313 ENSG00000087245 MMP2 matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
135 NA 135 ENSG00000128271 ADORA2A adenosine A2a receptor
5292 NA 5292 ENSG00000137193 PIM1 pim-1 oncogene
259236 NA 259236 ENSG00000181585 TMIE transmembrane inner ear
30819 NA 30819 ENSG00000120049 KCNIP2 Kv channel interacting protein 2
960 NA 960 ENSG00000026508 CD44 CD44 molecule (Indian blood group)
6774 NA 6774 ENSG00000168610 STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
9475 NA 9475 ENSG00000134318 ROCK2 Rho-associated, coiled-coil containing protein kinase 2
187 NA 187 NULL APLNR apelin receptor
7471 NA 7471 ENSG00000125084 WNT1 wingless-type MMTV integration site family, member 1
4851 NA 4851 ENSG00000148400 NOTCH1 notch 1
7923 NA 7923 ENSG00000204228 HSD17B8 hydroxysteroid (17-beta) dehydrogenase 8
387 NA 387 ENSG00000067560 RHOA ras homolog family member A
2104 NA 2104 ENSG00000196482 ESRRG estrogen-related receptor gamma
57626 NA 57626 ENSG00000150361 KLHL1 kelch-like 1 (Drosophila)
6262 NA 6262 ENSG00000198626 RYR2 ryanodine receptor 2 (cardiac)
23365 NA 23365 ENSG00000196914 ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12
2353 NA 2353 ENSG00000170345 FOS FBJ murine osteosarcoma viral oncogene homolog
388 NA 388 ENSG00000143878 RHOB ras homolog family member B
8412 NA 8412 ENSG00000137936 BCAR3 breast cancer anti-estrogen resistance 3
961 NA 961 ENSG00000196776 CD47 CD47 molecule
652 NA 652 ENSG00000125378 BMP4 bone morphogenetic protein 4
2101 NA 2101 ENSG00000173153 ESRRA estrogen-related receptor alpha
2099 NA 2099 ENSG00000091831 ESR1 estrogen receptor 1
Transcription Target----hsa_TATAAA_VTATA_01----DB_ID:2456
C=1276;O=48;E=10.09;R=4.76;rawP=3.95e-19;adjP=7.12e-17
7223 NA 7223 ENSG00000133107 TRPC4 transient receptor potential cation channel, subfamily C, member 4
3397 NA 3397 ENSG00000125968 ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
2335 NA 2335 ENSG00000115414 FN1 fibronectin 1
1636 NA 1636 ENSG00000159640 ACE angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
81839 NA 81839 ENSG00000173218 VANGL1 vang-like 1 (van gogh, Drosophila)
5166 NA 5166 ENSG00000004799 PDK4 pyruvate dehydrogenase kinase, isozyme 4
1950 NA 1950 ENSG00000138798 EGF epidermal growth factor
3596 NA 3596 ENSG00000169194 IL13 interleukin 13
3398 NA 3398 ENSG00000115738 ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
4842 NA 4842 ENSG00000089250 NOS1 nitric oxide synthase 1 (neuronal)
9518 NA 9518 ENSG00000130513 GDF15 growth differentiation factor 15
2355 NA 2355 ENSG00000075426 FOSL2 FOS-like antigen 2
5566 NA 5566 ENSG00000072062 PRKACA protein kinase, cAMP-dependent, catalytic, alpha
5155 NA 5155 ENSG00000100311 PDGFB platelet-derived growth factor beta polypeptide
3383 NA 3383 ENSG00000090339 ICAM1 intercellular adhesion molecule 1
4223 NA 4223 ENSG00000106511 MEOX2 mesenchyme homeobox 2
1490 NA 1490 ENSG00000118523 CTGF connective tissue growth factor
10911 NA 10911 ENSG00000049247 UTS2 urotensin 2
7124 NA 7124 ENSG00000232810 TNF tumor necrosis factor
387 NA 387 ENSG00000067560 RHOA ras homolog family member A
468 NA 468 ENSG00000128272 ATF4 activating transcription factor 4 (tax-responsive enhancer element B67)
4093 NA 4093 ENSG00000120693 SMAD9 SMAD family member 9
5617 NA 5617 ENSG00000172179 PRL prolactin
5468 NA 5468 ENSG00000132170 PPARG peroxisome proliferator-activated receptor gamma
2104 NA 2104 ENSG00000196482 ESRRG estrogen-related receptor gamma
6275 NA 6275 ENSG00000196154 S100A4 S100 calcium binding protein A4
1906 NA 1906 ENSG00000078401 EDN1 endothelin 1
57626 NA 57626 ENSG00000150361 KLHL1 kelch-like 1 (Drosophila)
9068 NA 9068 ENSG00000116194 ANGPTL1 angiopoietin-like 1
8743 NA 8743 ENSG00000121858 TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
6988 NA 6988 ENSG00000145022 TCTA T-cell leukemia translocation altered
2100 NA 2100 ENSG00000140009 ESR2 estrogen receptor 2 (ER beta)
2353 NA 2353 ENSG00000170345 FOS FBJ murine osteosarcoma viral oncogene homolog
1073 NA 1073 ENSG00000165410 CFL2 cofilin 2 (muscle)
1051 NA 1051 ENSG00000172216 CEBPB CCAAT/enhancer binding protein (C/EBP), beta
4088 NA 4088 ENSG00000166949 SMAD3 SMAD family member 3
185 NA 185 ENSG00000144891 AGTR1 angiotensin II receptor, type 1
4314 NA 4314 ENSG00000149968 MMP3 matrix metallopeptidase 3 (stromelysin 1, progelatinase)
56937 NA 56937 ENSG00000124225 PMEPA1 prostate transmembrane protein, androgen induced 1
7432 NA 7432 ENSG00000146469 VIP vasoactive intestinal peptide
51378 NA 51378 ENSG00000101280 ANGPT4 angiopoietin 4
5054 NA 5054 ENSG00000106366 SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
7412 NA 7412 ENSG00000162692 VCAM1 vascular cell adhesion molecule 1
2852 NA 2852 ENSG00000164850 GPER G protein-coupled estrogen receptor 1
10891 NA 10891 ENSG00000109819 PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
284 NA 284 ENSG00000154188 ANGPT1 angiopoietin 1
4843 NA 4843 ENSG00000007171 NOS2 nitric oxide synthase 2, inducible
658 NA 658 ENSG00000138696 BMPR1B bone morphogenetic protein receptor, type IB
Transcription Target----hsa_TTGTTT_VFOXO4_01----DB_ID:2416
C=2037;O=58;E=16.11;R=3.60;rawP=2.37e-17;adjP=3.21e-15
3351 NA 3351 ENSG00000135312 HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
7010 NA 7010 ENSG00000120156 TEK TEK tyrosine kinase, endothelial
7223 NA 7223 ENSG00000133107 TRPC4 transient receptor potential cation channel, subfamily C, member 4
3397 NA 3397 ENSG00000125968 ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
659 NA 659 ENSG00000204217 BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase)
2335 NA 2335 ENSG00000115414 FN1 fibronectin 1
959 NA 959 ENSG00000102245 CD40LG CD40 ligand
5166 NA 5166 ENSG00000004799 PDK4 pyruvate dehydrogenase kinase, isozyme 4
7157 NA 7157 ENSG00000141510 TP53 tumor protein p53
3398 NA 3398 ENSG00000115738 ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
4090 NA 4090 ENSG00000113658 SMAD5 SMAD family member 5
2355 NA 2355 ENSG00000075426 FOSL2 FOS-like antigen 2
284273 NA 284273 ENSG00000180011 ZADH2 zinc binding alcohol dehydrogenase domain containing 2
5156 NA 5156 ENSG00000134853 PDGFRA platelet-derived growth factor receptor, alpha polypeptide
5155 NA 5155 ENSG00000100311 PDGFB platelet-derived growth factor beta polypeptide
3037 NA 3037 ENSG00000170961 HAS2 hyaluronan synthase 2
4223 NA 4223 ENSG00000106511 MEOX2 mesenchyme homeobox 2
7474 NA 7474 ENSG00000114251 WNT5A wingless-type MMTV integration site family, member 5A
5154 NA 5154 ENSG00000197461 PDGFA platelet-derived growth factor alpha polypeptide
3662 NA 3662 ENSG00000137265 IRF4 interferon regulatory factor 4
5164 NA 5164 ENSG00000005882 PDK2 pyruvate dehydrogenase kinase, isozyme 2
4775 NA 4775 ENSG00000072736 NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
5136 NA 5136 ENSG00000115252 PDE1A phosphodiesterase 1A, calmodulin-dependent
114907 NA 114907 ENSG00000156804 FBXO32 F-box protein 32
3480 NA 3480 ENSG00000140443 IGF1R insulin-like growth factor 1 receptor
1499 NA 1499 ENSG00000168036 CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
1027 NA 1027 ENSG00000111276 CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
6387 NA 6387 ENSG00000107562 CXCL12 chemokine (C-X-C motif) ligand 12
6348 NA 6348 ENSG00000006075 CCL3 chemokine (C-C motif) ligand 3
5292 NA 5292 ENSG00000137193 PIM1 pim-1 oncogene
30819 NA 30819 ENSG00000120049 KCNIP2 Kv channel interacting protein 2
6774 NA 6774 ENSG00000168610 STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
50507 NA 50507 ENSG00000086991 NOX4 NADPH oxidase 4
5159 NA 5159 ENSG00000113721 PDGFRB platelet-derived growth factor receptor, beta polypeptide
1843 NA 1843 ENSG00000120129 DUSP1 dual specificity phosphatase 1
9166 NA 9166 ENSG00000147654 EBAG9 estrogen receptor binding site associated, antigen, 9
4846 NA 4846 ENSG00000164867 NOS3 nitric oxide synthase 3 (endothelial cell)
993 NA 993 ENSG00000164045 CDC25A cell division cycle 25 homolog A (S. pombe)
1373 NA 1373 ENSG00000021826 CPS1 carbamoyl-phosphate synthase 1, mitochondrial
2104 NA 2104 ENSG00000196482 ESRRG estrogen-related receptor gamma
134549 NA 134549 ENSG00000164403 SHROOM1 shroom family member 1
2977 NA 2977 ENSG00000152402 GUCY1A2 guanylate cyclase 1, soluble, alpha 2
1073 NA 1073 ENSG00000165410 CFL2 cofilin 2 (muscle)
388 NA 388 ENSG00000143878 RHOB ras homolog family member B
4088 NA 4088 ENSG00000166949 SMAD3 SMAD family member 3
51170 NA 51170 ENSG00000198189 HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
51554 NA 51554 ENSG00000129048 CCRL1 chemokine (C-C motif) receptor-like 1
3091 NA 3091 ENSG00000100644 HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
2643 NA 2643 ENSG00000131979 GCH1 GTP cyclohydrolase 1
7450 NA 7450 ENSG00000110799 VWF von Willebrand factor
22926 NA 22926 ENSG00000118217 ATF6 activating transcription factor 6
688 NA 688 ENSG00000102554 KLF5 Kruppel-like factor 5 (intestinal)
652 NA 652 ENSG00000125378 BMP4 bone morphogenetic protein 4
6093 NA 6093 ENSG00000067900 ROCK1 Rho-associated, coiled-coil containing protein kinase 1
10891 NA 10891 ENSG00000109819 PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
4086 NA 4086 ENSG00000170365 SMAD1 SMAD family member 1
7292 NA 7292 ENSG00000117586 TNFSF4 tumor necrosis factor (ligand) superfamily, member 4
284 NA 284 ENSG00000154188 ANGPT1 angiopoietin 1
Transcription Target----hsa_TTANTCA_UNKNOWN----DB_ID:2372
C=937;O=37;E=7.41;R=4.99;rawP=1.38e-15;adjP=1.49e-13
659 NA 659 ENSG00000204217 BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase)
959 NA 959 ENSG00000102245 CD40LG CD40 ligand
3596 NA 3596 ENSG00000169194 IL13 interleukin 13
6648 NA 6648 ENSG00000112096 SOD2 superoxide dismutase 2, mitochondrial
3337 NA 3337 ENSG00000132002 DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
8996 NA 8996 ENSG00000140939 NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain)
2355 NA 2355 ENSG00000075426 FOSL2 FOS-like antigen 2
10666 NA 10666 ENSG00000150637 CD226 CD226 molecule
5136 NA 5136 ENSG00000115252 PDE1A phosphodiesterase 1A, calmodulin-dependent
7076 NA 7076 ENSG00000102265 TIMP1 TIMP metallopeptidase inhibitor 1
3480 NA 3480 ENSG00000140443 IGF1R insulin-like growth factor 1 receptor
259236 NA 259236 ENSG00000181585 TMIE transmembrane inner ear
6863 NA 6863 ENSG00000006128 TAC1 tachykinin, precursor 1
5292 NA 5292 ENSG00000137193 PIM1 pim-1 oncogene
960 NA 960 ENSG00000026508 CD44 CD44 molecule (Indian blood group)
30819 NA 30819 ENSG00000120049 KCNIP2 Kv channel interacting protein 2
1843 NA 1843 ENSG00000120129 DUSP1 dual specificity phosphatase 1
26585 NA 26585 ENSG00000166923 GREM1 gremlin 1
4851 NA 4851 ENSG00000148400 NOTCH1 notch 1
5617 NA 5617 ENSG00000172179 PRL prolactin
2104 NA 2104 ENSG00000196482 ESRRG estrogen-related receptor gamma
1906 NA 1906 ENSG00000078401 EDN1 endothelin 1
6262 NA 6262 ENSG00000198626 RYR2 ryanodine receptor 2 (cardiac)
7422 NA 7422 ENSG00000112715 VEGFA vascular endothelial growth factor A
1051 NA 1051 ENSG00000172216 CEBPB CCAAT/enhancer binding protein (C/EBP), beta
8412 NA 8412 ENSG00000137936 BCAR3 breast cancer anti-estrogen resistance 3
2103 NA 2103 ENSG00000119715 ESRRB estrogen-related receptor beta
4088 NA 4088 ENSG00000166949 SMAD3 SMAD family member 3
5743 NA 5743 ENSG00000073756 PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
4314 NA 4314 ENSG00000149968 MMP3 matrix metallopeptidase 3 (stromelysin 1, progelatinase)
3984 NA 3984 ENSG00000106683 LIMK1 LIM domain kinase 1
7432 NA 7432 ENSG00000146469 VIP vasoactive intestinal peptide
688 NA 688 ENSG00000102554 KLF5 Kruppel-like factor 5 (intestinal)
3082 NA 3082 ENSG00000019991 HGF hepatocyte growth factor (hepapoietin A; scatter factor)
652 NA 652 ENSG00000125378 BMP4 bone morphogenetic protein 4
4086 NA 4086 ENSG00000170365 SMAD1 SMAD family member 1
7292 NA 7292 ENSG00000117586 TNFSF4 tumor necrosis factor (ligand) superfamily, member 4
Transcription Target----hsa_CAGCTG_VAP4_Q5----DB_ID:2403
C=1502;O=46;E=11.88;R=3.87;rawP=5.12e-15;adjP=4.62e-13
7223 NA 7223 ENSG00000133107 TRPC4 transient receptor potential cation channel, subfamily C, member 4
6331 NA 6331 ENSG00000183873 SCN5A sodium channel, voltage-gated, type V, alpha subunit
3397 NA 3397 ENSG00000125968 ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
659 NA 659 ENSG00000204217 BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase)
1908 NA 1908 ENSG00000124205 EDN3 endothelin 3
1636 NA 1636 ENSG00000159640 ACE angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
3162 NA 3162 ENSG00000100292 HMOX1 heme oxygenase (decycling) 1
5566 NA 5566 ENSG00000072062 PRKACA protein kinase, cAMP-dependent, catalytic, alpha
7048 NA 7048 ENSG00000163513 TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
5155 NA 5155 ENSG00000100311 PDGFB platelet-derived growth factor beta polypeptide
6714 NA 6714 ENSG00000197122 SRC v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
5164 NA 5164 ENSG00000005882 PDK2 pyruvate dehydrogenase kinase, isozyme 2
5136 NA 5136 ENSG00000115252 PDE1A phosphodiesterase 1A, calmodulin-dependent
3480 NA 3480 ENSG00000140443 IGF1R insulin-like growth factor 1 receptor
57060 NA 57060 ENSG00000090097 PCBP4 poly(rC) binding protein 4
1027 NA 1027 ENSG00000111276 CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
3913 NA 3913 ENSG00000172037 LAMB2 laminin, beta 2 (laminin S)
30819 NA 30819 ENSG00000120049 KCNIP2 Kv channel interacting protein 2
6774 NA 6774 ENSG00000168610 STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
1843 NA 1843 ENSG00000120129 DUSP1 dual specificity phosphatase 1
4851 NA 4851 ENSG00000148400 NOTCH1 notch 1
1373 NA 1373 ENSG00000021826 CPS1 carbamoyl-phosphate synthase 1, mitochondrial
7923 NA 7923 ENSG00000204228 HSD17B8 hydroxysteroid (17-beta) dehydrogenase 8
207 NA 207 ENSG00000142208 AKT1 v-akt murine thymoma viral oncogene homolog 1
8862 NA 8862 ENSG00000171388 APLN apelin
2104 NA 2104 ENSG00000196482 ESRRG estrogen-related receptor gamma
5739 NA 5739 ENSG00000160013 PTGIR prostaglandin I2 (prostacyclin) receptor (IP)
3309 NA 3309 ENSG00000044574 HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
57626 NA 57626 ENSG00000150361 KLHL1 kelch-like 1 (Drosophila)
4035 NA 4035 ENSG00000123384 LRP1 low density lipoprotein receptor-related protein 1
7422 NA 7422 ENSG00000112715 VEGFA vascular endothelial growth factor A
2103 NA 2103 ENSG00000119715 ESRRB estrogen-related receptor beta
3091 NA 3091 ENSG00000100644 HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
7494 NA 7494 ENSG00000100219 XBP1 X-box binding protein 1
961 NA 961 ENSG00000196776 CD47 CD47 molecule
6259 NA 6259 ENSG00000163785 RYK receptor-like tyrosine kinase
23417 NA 23417 ENSG00000103150 MLYCD malonyl-CoA decarboxylase
51378 NA 51378 ENSG00000101280 ANGPT4 angiopoietin 4
5054 NA 5054 ENSG00000106366 SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
688 NA 688 ENSG00000102554 KLF5 Kruppel-like factor 5 (intestinal)
6093 NA 6093 ENSG00000067900 ROCK1 Rho-associated, coiled-coil containing protein kinase 1
7292 NA 7292 ENSG00000117586 TNFSF4 tumor necrosis factor (ligand) superfamily, member 4
2101 NA 2101 ENSG00000173153 ESRRA estrogen-related receptor alpha
2099 NA 2099 ENSG00000091831 ESR1 estrogen receptor 1
2006 NA 2006 ENSG00000049540 ELN elastin
284 NA 284 ENSG00000154188 ANGPT1 angiopoietin 1
Transcription Target----hsa_VCEBPB_02----DB_ID:1922
C=252;O=19;E=1.99;R=9.54;rawP=2.29e-13;adjP=1.55e-11
5468 NA 5468 ENSG00000132170 PPARG peroxisome proliferator-activated receptor gamma
5157 NA 5157 ENSG00000104213 PDGFRL platelet-derived growth factor receptor-like
284273 NA 284273 ENSG00000180011 ZADH2 zinc binding alcohol dehydrogenase domain containing 2
5156 NA 5156 ENSG00000134853 PDGFRA platelet-derived growth factor receptor, alpha polypeptide
5155 NA 5155 ENSG00000100311 PDGFB platelet-derived growth factor beta polypeptide
4223 NA 4223 ENSG00000106511 MEOX2 mesenchyme homeobox 2
388 NA 388 ENSG00000143878 RHOB ras homolog family member B
7474 NA 7474 ENSG00000114251 WNT5A wingless-type MMTV integration site family, member 5A
1907 NA 1907 ENSG00000127129 EDN2 endothelin 2
6532 NA 6532 ENSG00000108576 SLC6A4 solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
1027 NA 1027 ENSG00000111276 CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
3952 NA 3952 ENSG00000174697 LEP leptin
6863 NA 6863 ENSG00000006128 TAC1 tachykinin, precursor 1
6348 NA 6348 ENSG00000006075 CCL3 chemokine (C-C motif) ligand 3
4086 NA 4086 ENSG00000170365 SMAD1 SMAD family member 1
2099 NA 2099 ENSG00000091831 ESR1 estrogen receptor 1
6774 NA 6774 ENSG00000168610 STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
284 NA 284 ENSG00000154188 ANGPT1 angiopoietin 1
1843 NA 1843 ENSG00000120129 DUSP1 dual specificity phosphatase 1
Transcription Target----hsa_GGGCGGR_VSP1_Q6----DB_ID:2452
C=2891;O=63;E=22.86;R=2.76;rawP=2.10e-13;adjP=1.55e-11
7223 NA 7223 ENSG00000133107 TRPC4 transient receptor potential cation channel, subfamily C, member 4
659 NA 659 ENSG00000204217 BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase)
1908 NA 1908 ENSG00000124205 EDN3 endothelin 3
5166 NA 5166 ENSG00000004799 PDK4 pyruvate dehydrogenase kinase, isozyme 4
7157 NA 7157 ENSG00000141510 TP53 tumor protein p53
331 NA 331 ENSG00000101966 XIAP X-linked inhibitor of apoptosis
57142 NA 57142 ENSG00000115310 RTN4 reticulon 4
51478 NA 51478 ENSG00000132196 HSD17B7 hydroxysteroid (17-beta) dehydrogenase 7
5460 NA 5460 ENSG00000204531 POU5F1 POU class 5 homeobox 1
284273 NA 284273 ENSG00000180011 ZADH2 zinc binding alcohol dehydrogenase domain containing 2
5566 NA 5566 ENSG00000072062 PRKACA protein kinase, cAMP-dependent, catalytic, alpha
4485 NA 4485 ENSG00000173531 MST1 macrophage stimulating 1 (hepatocyte growth factor-like)
5155 NA 5155 ENSG00000100311 PDGFB platelet-derived growth factor beta polypeptide
3037 NA 3037 ENSG00000170961 HAS2 hyaluronan synthase 2
10956 NA 10956 ENSG00000135506 OS9 osteosarcoma amplified 9, endoplasmic reticulum lectin
7474 NA 7474 ENSG00000114251 WNT5A wingless-type MMTV integration site family, member 5A
650 NA 650 ENSG00000125845 BMP2 bone morphogenetic protein 2
3480 NA 3480 ENSG00000140443 IGF1R insulin-like growth factor 1 receptor
7076 NA 7076 ENSG00000102265 TIMP1 TIMP metallopeptidase inhibitor 1
57060 NA 57060 ENSG00000090097 PCBP4 poly(rC) binding protein 4
386724 NA 386724 ENSG00000176020 AMIGO3 adhesion molecule with Ig-like domain 3
51517 NA 51517 ENSG00000213672 NCKIPSD NCK interacting protein with SH3 domain
1027 NA 1027 ENSG00000111276 CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
348 NA 348 ENSG00000130203 APOE apolipoprotein E
3952 NA 3952 ENSG00000174697 LEP leptin
5292 NA 5292 ENSG00000137193 PIM1 pim-1 oncogene
4791 NA 4791 ENSG00000077150 NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
30819 NA 30819 ENSG00000120049 KCNIP2 Kv channel interacting protein 2
846 NA 846 ENSG00000036828 CASR calcium-sensing receptor
29843 NA 29843 ENSG00000079387 SENP1 SUMO1/sentrin specific peptidase 1
1072 NA 1072 ENSG00000172757 CFL1 cofilin 1 (non-muscle)
1849 NA 1849 ENSG00000164086 DUSP7 dual specificity phosphatase 7
1843 NA 1843 ENSG00000120129 DUSP1 dual specificity phosphatase 1
9166 NA 9166 ENSG00000147654 EBAG9 estrogen receptor binding site associated, antigen, 9
7040 NA 7040 ENSG00000105329 TGFB1 transforming growth factor, beta 1
7124 NA 7124 ENSG00000232810 TNF tumor necrosis factor
7471 NA 7471 ENSG00000125084 WNT1 wingless-type MMTV integration site family, member 1
4851 NA 4851 ENSG00000148400 NOTCH1 notch 1
1394 NA 1394 ENSG00000120088 CRHR1 corticotropin releasing hormone receptor 1
993 NA 993 ENSG00000164045 CDC25A cell division cycle 25 homolog A (S. pombe)
387 NA 387 ENSG00000067560 RHOA ras homolog family member A
8862 NA 8862 ENSG00000171388 APLN apelin
3309 NA 3309 ENSG00000044574 HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
4035 NA 4035 ENSG00000123384 LRP1 low density lipoprotein receptor-related protein 1
826 NA 826 ENSG00000126247 CAPNS1 calpain, small subunit 1
6988 NA 6988 ENSG00000145022 TCTA T-cell leukemia translocation altered
7422 NA 7422 ENSG00000112715 VEGFA vascular endothelial growth factor A
3953 NA 3953 ENSG00000116678 LEPR leptin receptor
1073 NA 1073 ENSG00000165410 CFL2 cofilin 2 (muscle)
1051 NA 1051 ENSG00000172216 CEBPB CCAAT/enhancer binding protein (C/EBP), beta
4088 NA 4088 ENSG00000166949 SMAD3 SMAD family member 3
1907 NA 1907 ENSG00000127129 EDN2 endothelin 2
4087 NA 4087 ENSG00000175387 SMAD2 SMAD family member 2
10059 NA 10059 ENSG00000087470 DNM1L dynamin 1-like
56937 NA 56937 ENSG00000124225 PMEPA1 prostate transmembrane protein, androgen induced 1
2983 NA 2983 ENSG00000061918 GUCY1B3 guanylate cyclase 1, soluble, beta 3
4134 NA 4134 ENSG00000047849 MAP4 microtubule-associated protein 4
4128 NA 4128 ENSG00000189221 MAOA monoamine oxidase A
3065 NA 3065 ENSG00000116478 HDAC1 histone deacetylase 1
688 NA 688 ENSG00000102554 KLF5 Kruppel-like factor 5 (intestinal)
652 NA 652 ENSG00000125378 BMP4 bone morphogenetic protein 4
2006 NA 2006 ENSG00000049540 ELN elastin
284 NA 284 ENSG00000154188 ANGPT1 angiopoietin 1
Transcription Target----hsa_WGGAATGY_VTEF1_Q6----DB_ID:2458
C=370;O=22;E=2.93;R=7.52;rawP=3.60e-13;adjP=2.16e-11
7223 NA 7223 ENSG00000133107 TRPC4 transient receptor potential cation channel, subfamily C, member 4
26585 NA 26585 ENSG00000166923 GREM1 gremlin 1
468 NA 468 ENSG00000128272 ATF4 activating transcription factor 4 (tax-responsive enhancer element B67)
659 NA 659 ENSG00000204217 BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase)
27302 NA 27302 ENSG00000163217 BMP10 bone morphogenetic protein 10
1906 NA 1906 ENSG00000078401 EDN1 endothelin 1
3398 NA 3398 ENSG00000115738 ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
857 NA 857 ENSG00000105974 CAV1 caveolin 1, caveolae protein, 22kDa
5156 NA 5156 ENSG00000134853 PDGFRA platelet-derived growth factor receptor, alpha polypeptide
1073 NA 1073 ENSG00000165410 CFL2 cofilin 2 (muscle)
5154 NA 5154 ENSG00000197461 PDGFA platelet-derived growth factor alpha polypeptide
4088 NA 4088 ENSG00000166949 SMAD3 SMAD family member 3
5136 NA 5136 ENSG00000115252 PDE1A phosphodiesterase 1A, calmodulin-dependent
1490 NA 1490 ENSG00000118523 CTGF connective tissue growth factor
348 NA 348 ENSG00000130203 APOE apolipoprotein E
3913 NA 3913 ENSG00000172037 LAMB2 laminin, beta 2 (laminin S)
652 NA 652 ENSG00000125378 BMP4 bone morphogenetic protein 4
4791 NA 4791 ENSG00000077150 NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
2099 NA 2099 ENSG00000091831 ESR1 estrogen receptor 1
284 NA 284 ENSG00000154188 ANGPT1 angiopoietin 1
9475 NA 9475 ENSG00000134318 ROCK2 Rho-associated, coiled-coil containing protein kinase 2
1849 NA 1849 ENSG00000164086 DUSP7 dual specificity phosphatase 7
Transcription Target----hsa_RTAAACA_VFREAC2_01----DB_ID:2417
C=907;O=33;E=7.17;R=4.60;rawP=4.90e-13;adjP=2.65e-11
7010 NA 7010 ENSG00000120156 TEK TEK tyrosine kinase, endothelial
7223 NA 7223 ENSG00000133107 TRPC4 transient receptor potential cation channel, subfamily C, member 4
26585 NA 26585 ENSG00000166923 GREM1 gremlin 1
4093 NA 4093 ENSG00000120693 SMAD9 SMAD family member 9
2104 NA 2104 ENSG00000196482 ESRRG estrogen-related receptor gamma
27302 NA 27302 ENSG00000163217 BMP10 bone morphogenetic protein 10
5166 NA 5166 ENSG00000004799 PDK4 pyruvate dehydrogenase kinase, isozyme 4
1906 NA 1906 ENSG00000078401 EDN1 endothelin 1
57626 NA 57626 ENSG00000150361 KLHL1 kelch-like 1 (Drosophila)
134549 NA 134549 ENSG00000164403 SHROOM1 shroom family member 1
4035 NA 4035 ENSG00000123384 LRP1 low density lipoprotein receptor-related protein 1
3398 NA 3398 ENSG00000115738 ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
4090 NA 4090 ENSG00000113658 SMAD5 SMAD family member 5
2355 NA 2355 ENSG00000075426 FOSL2 FOS-like antigen 2
2353 NA 2353 ENSG00000170345 FOS FBJ murine osteosarcoma viral oncogene homolog
5566 NA 5566 ENSG00000072062 PRKACA protein kinase, cAMP-dependent, catalytic, alpha
5155 NA 5155 ENSG00000100311 PDGFB platelet-derived growth factor beta polypeptide
1073 NA 1073 ENSG00000165410 CFL2 cofilin 2 (muscle)
595 NA 595 ENSG00000110092 CCND1 cyclin D1
51170 NA 51170 ENSG00000198189 HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
650 NA 650 ENSG00000125845 BMP2 bone morphogenetic protein 2
3662 NA 3662 ENSG00000137265 IRF4 interferon regulatory factor 4
5136 NA 5136 ENSG00000115252 PDE1A phosphodiesterase 1A, calmodulin-dependent
4775 NA 4775 ENSG00000072736 NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
1490 NA 1490 ENSG00000118523 CTGF connective tissue growth factor
3480 NA 3480 ENSG00000140443 IGF1R insulin-like growth factor 1 receptor
5740 NA 5740 ENSG00000124212 PTGIS prostaglandin I2 (prostacyclin) synthase
1027 NA 1027 ENSG00000111276 CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
652 NA 652 ENSG00000125378 BMP4 bone morphogenetic protein 4
4086 NA 4086 ENSG00000170365 SMAD1 SMAD family member 1
10891 NA 10891 ENSG00000109819 PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
1843 NA 1843 ENSG00000120129 DUSP1 dual specificity phosphatase 1
1491 NA 1491 ENSG00000116761 CTH cystathionase (cystathionine gamma-lyase)


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