|
Organism: Hsapiens, Id Type: entrezgene, Ref Set: entrezgene, Significance Level: Top10, Statistics Test: Hypergeometric, MTC: BH, Minimum: 2 The results for each enriched gene set are listed in this table. For each gene set, the first row lists the gene set name, and corresponding Gene Set ID. The second row lists number of reference genes in the category (C), number of genes in the gene set and also in the category (O), expected number in the category (E), Ratio of enrichment (R), p value from hypergeometric test (rawP), and p value adjusted by the multiple test adjustment (adjP). Finally, genes in the gene set are listed. For each gene, the table lists the user uploaded ID and value (optional), Entrez ID, Ensembl Gene Stable ID, Gene symbol, and description. Ensembl Gene Stable ID and Entrez Gene ID are linked to the Ensembl and Entrez Gene databases, respectively. | |||||
| disease----Hypertension, Pulmonary----DB_ID:PA444555 | |||||
| C=74;O=45;E=0.59;R=76.91;rawP=3.24e-76;adjP=4.06e-73 | |||||
| 384 | NA | 384 | ENSG00000081181 | ARG2 | arginase, type II |
| 3397 | NA | 3397 | ENSG00000125968 | ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
| 659 | NA | 659 | ENSG00000204217 | BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) |
| 1908 | NA | 1908 | ENSG00000124205 | EDN3 | endothelin 3 |
| 1636 | NA | 1636 | ENSG00000159640 | ACE | angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 |
| 4090 | NA | 4090 | ENSG00000113658 | SMAD5 | SMAD family member 5 |
| 8200 | NA | 8200 | ENSG00000125965 | GDF5 | growth differentiation factor 5 |
| 2022 | NA | 2022 | ENSG00000106991 | ENG | endoglin |
| 650 | NA | 650 | ENSG00000125845 | BMP2 | bone morphogenetic protein 2 |
| 5592 | NA | 5592 | ENSG00000185532 | PRKG1 | protein kinase, cGMP-dependent, type I |
| 2658 | NA | 2658 | ENSG00000128802 | GDF2 | growth differentiation factor 2 |
| 1910 | NA | 1910 | ENSG00000136160 | EDNRB | endothelin receptor type B |
| 1889 | NA | 1889 | ENSG00000117298 | ECE1 | endothelin converting enzyme 1 |
| 10911 | NA | 10911 | ENSG00000049247 | UTS2 | urotensin 2 |
| 9475 | NA | 9475 | ENSG00000134318 | ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 |
| 50507 | NA | 50507 | ENSG00000086991 | NOX4 | NADPH oxidase 4 |
| 5159 | NA | 5159 | ENSG00000113721 | PDGFRB | platelet-derived growth factor receptor, beta polypeptide |
| 4846 | NA | 4846 | ENSG00000164867 | NOS3 | nitric oxide synthase 3 (endothelial cell) |
| 7040 | NA | 7040 | ENSG00000105329 | TGFB1 | transforming growth factor, beta 1 |
| 1373 | NA | 1373 | ENSG00000021826 | CPS1 | carbamoyl-phosphate synthase 1, mitochondrial |
| 387 | NA | 387 | ENSG00000067560 | RHOA | ras homolog family member A |
| 4093 | NA | 4093 | ENSG00000120693 | SMAD9 | SMAD family member 9 |
| 5468 | NA | 5468 | ENSG00000132170 | PPARG | peroxisome proliferator-activated receptor gamma |
| 6275 | NA | 6275 | ENSG00000196154 | S100A4 | S100 calcium binding protein A4 |
| 1906 | NA | 1906 | ENSG00000078401 | EDN1 | endothelin 1 |
| 3741 | NA | 3741 | ENSG00000130037 | KCNA5 | potassium voltage-gated channel, shaker-related subfamily, member 5 |
| 857 | NA | 857 | ENSG00000105974 | CAV1 | caveolin 1, caveolae protein, 22kDa |
| 1909 | NA | 1909 | ENSG00000151617 | EDNRA | endothelin receptor type A |
| 51170 | NA | 51170 | ENSG00000198189 | HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 |
| 185 | NA | 185 | ENSG00000144891 | AGTR1 | angiotensin II receptor, type 1 |
| 6532 | NA | 6532 | ENSG00000108576 | SLC6A4 | solute carrier family 6 (neurotransmitter transporter, serotonin), member 4 |
| 3091 | NA | 3091 | ENSG00000100644 | HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) |
| 94 | NA | 94 | ENSG00000139567 | ACVRL1 | activin A receptor type II-like 1 |
| 5740 | NA | 5740 | ENSG00000124212 | PTGIS | prostaglandin I2 (prostacyclin) synthase |
| 3357 | NA | 3357 | ENSG00000135914 | HTR2B | 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled |
| 7225 | NA | 7225 | ENSG00000137672 | TRPC6 | transient receptor potential cation channel, subfamily C, member 6 |
| 4879 | NA | 4879 | ENSG00000120937 | NPPB | natriuretic peptide B |
| 657 | NA | 657 | ENSG00000107779 | BMPR1A | bone morphogenetic protein receptor, type IA |
| 652 | NA | 652 | ENSG00000125378 | BMP4 | bone morphogenetic protein 4 |
| 6093 | NA | 6093 | ENSG00000067900 | ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 |
| 4086 | NA | 4086 | ENSG00000170365 | SMAD1 | SMAD family member 1 |
| 4089 | NA | 4089 | ENSG00000141646 | SMAD4 | SMAD family member 4 |
| 284 | NA | 284 | ENSG00000154188 | ANGPT1 | angiopoietin 1 |
| 658 | NA | 658 | ENSG00000138696 | BMPR1B | bone morphogenetic protein receptor, type IB |
| 7498 | NA | 7498 | ENSG00000158125 | XDH | xanthine dehydrogenase |
| disease----Hepatopulmonary syndrome----DB_ID:PA165108142 | |||||
| C=84;O=40;E=0.66;R=60.22;rawP=8.86e-62;adjP=5.55e-59 | |||||
| 1588 | NA | 1588 | ENSG00000137869 | CYP19A1 | cytochrome P450, family 19, subfamily A, polypeptide 1 |
| 659 | NA | 659 | ENSG00000204217 | BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) |
| 6347 | NA | 6347 | ENSG00000108691 | CCL2 | chemokine (C-C motif) ligand 2 |
| 6462 | NA | 6462 | ENSG00000129214 | SHBG | sex hormone-binding globulin |
| 6648 | NA | 6648 | ENSG00000112096 | SOD2 | superoxide dismutase 2, mitochondrial |
| 5578 | NA | 5578 | ENSG00000154229 | PRKCA | protein kinase C, alpha |
| 3162 | NA | 3162 | ENSG00000100292 | HMOX1 | heme oxygenase (decycling) 1 |
| 3371 | NA | 3371 | ENSG00000041982 | TNC | tenascin C |
| 7057 | NA | 7057 | ENSG00000137801 | THBS1 | thrombospondin 1 |
| 2022 | NA | 2022 | ENSG00000106991 | ENG | endoglin |
| 2658 | NA | 2658 | ENSG00000128802 | GDF2 | growth differentiation factor 2 |
| 1910 | NA | 1910 | ENSG00000136160 | EDNRB | endothelin receptor type B |
| 1889 | NA | 1889 | ENSG00000117298 | ECE1 | endothelin converting enzyme 1 |
| 4791 | NA | 4791 | ENSG00000077150 | NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) |
| 9475 | NA | 9475 | ENSG00000134318 | ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 |
| 50507 | NA | 50507 | ENSG00000086991 | NOX4 | NADPH oxidase 4 |
| 4846 | NA | 4846 | ENSG00000164867 | NOS3 | nitric oxide synthase 3 (endothelial cell) |
| 7166 | NA | 7166 | ENSG00000129167 | TPH1 | tryptophan hydroxylase 1 |
| 6275 | NA | 6275 | ENSG00000196154 | S100A4 | S100 calcium binding protein A4 |
| 1906 | NA | 1906 | ENSG00000078401 | EDN1 | endothelin 1 |
| 3741 | NA | 3741 | ENSG00000130037 | KCNA5 | potassium voltage-gated channel, shaker-related subfamily, member 5 |
| 857 | NA | 857 | ENSG00000105974 | CAV1 | caveolin 1, caveolae protein, 22kDa |
| 2100 | NA | 2100 | ENSG00000140009 | ESR2 | estrogen receptor 2 (ER beta) |
| 1909 | NA | 1909 | ENSG00000151617 | EDNRA | endothelin receptor type A |
| 4088 | NA | 4088 | ENSG00000166949 | SMAD3 | SMAD family member 3 |
| 4087 | NA | 4087 | ENSG00000175387 | SMAD2 | SMAD family member 2 |
| 4314 | NA | 4314 | ENSG00000149968 | MMP3 | matrix metallopeptidase 3 (stromelysin 1, progelatinase) |
| 94 | NA | 94 | ENSG00000139567 | ACVRL1 | activin A receptor type II-like 1 |
| 5740 | NA | 5740 | ENSG00000124212 | PTGIS | prostaglandin I2 (prostacyclin) synthase |
| 3357 | NA | 3357 | ENSG00000135914 | HTR2B | 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled |
| 7225 | NA | 7225 | ENSG00000137672 | TRPC6 | transient receptor potential cation channel, subfamily C, member 6 |
| 7450 | NA | 7450 | ENSG00000110799 | VWF | von Willebrand factor |
| 4879 | NA | 4879 | ENSG00000120937 | NPPB | natriuretic peptide B |
| 5054 | NA | 5054 | ENSG00000106366 | SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 |
| 657 | NA | 657 | ENSG00000107779 | BMPR1A | bone morphogenetic protein receptor, type IA |
| 4089 | NA | 4089 | ENSG00000141646 | SMAD4 | SMAD family member 4 |
| 2006 | NA | 2006 | ENSG00000049540 | ELN | elastin |
| 284 | NA | 284 | ENSG00000154188 | ANGPT1 | angiopoietin 1 |
| 4843 | NA | 4843 | ENSG00000007171 | NOS2 | nitric oxide synthase 2, inducible |
| 7498 | NA | 7498 | ENSG00000158125 | XDH | xanthine dehydrogenase |
| disease----cancer or viral infections----DB_ID:PA128407012 | |||||
| C=951;O=81;E=7.52;R=10.77;rawP=8.68e-59;adjP=3.63e-56 | |||||
| 3292 | NA | 3292 | ENSG00000108786 | HSD17B1 | hydroxysteroid (17-beta) dehydrogenase 1 |
| 1588 | NA | 1588 | ENSG00000137869 | CYP19A1 | cytochrome P450, family 19, subfamily A, polypeptide 1 |
| 3397 | NA | 3397 | ENSG00000125968 | ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
| 3791 | NA | 3791 | ENSG00000128052 | KDR | kinase insert domain receptor (a type III receptor tyrosine kinase) |
| 5037 | NA | 5037 | ENSG00000089220 | PEBP1 | phosphatidylethanolamine binding protein 1 |
| 1950 | NA | 1950 | ENSG00000138798 | EGF | epidermal growth factor |
| 7157 | NA | 7157 | ENSG00000141510 | TP53 | tumor protein p53 |
| 6648 | NA | 6648 | ENSG00000112096 | SOD2 | superoxide dismutase 2, mitochondrial |
| 331 | NA | 331 | ENSG00000101966 | XIAP | X-linked inhibitor of apoptosis |
| 5157 | NA | 5157 | ENSG00000104213 | PDGFRL | platelet-derived growth factor receptor-like |
| 5460 | NA | 5460 | ENSG00000204531 | POU5F1 | POU class 5 homeobox 1 |
| 5155 | NA | 5155 | ENSG00000100311 | PDGFB | platelet-derived growth factor beta polypeptide |
| 5156 | NA | 5156 | ENSG00000134853 | PDGFRA | platelet-derived growth factor receptor, alpha polypeptide |
| 7474 | NA | 7474 | ENSG00000114251 | WNT5A | wingless-type MMTV integration site family, member 5A |
| 5154 | NA | 5154 | ENSG00000197461 | PDGFA | platelet-derived growth factor alpha polypeptide |
| 595 | NA | 595 | ENSG00000110092 | CCND1 | cyclin D1 |
| 494336 | NA | 494336 | NULL | MIR424 | microRNA 424 |
| 1499 | NA | 1499 | ENSG00000168036 | CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa |
| 1027 | NA | 1027 | ENSG00000111276 | CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) |
| 407018 | NA | 407018 | NULL | MIR27A | microRNA 27a |
| 841 | NA | 841 | ENSG00000064012 | CASP8 | caspase 8, apoptosis-related cysteine peptidase |
| 5159 | NA | 5159 | ENSG00000113721 | PDGFRB | platelet-derived growth factor receptor, beta polypeptide |
| 9166 | NA | 9166 | ENSG00000147654 | EBAG9 | estrogen receptor binding site associated, antigen, 9 |
| 1545 | NA | 1545 | ENSG00000138061 | CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
| 406881 | NA | 406881 | NULL | MIRLET7A1 | microRNA let-7a-1 |
| 406952 | NA | 406952 | NULL | MIR17 | microRNA 17 |
| 207 | NA | 207 | ENSG00000142208 | AKT1 | v-akt murine thymoma viral oncogene homolog 1 |
| 6275 | NA | 6275 | ENSG00000196154 | S100A4 | S100 calcium binding protein A4 |
| 3309 | NA | 3309 | ENSG00000044574 | HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) |
| 842 | NA | 842 | ENSG00000132906 | CASP9 | caspase 9, apoptosis-related cysteine peptidase |
| 406991 | NA | 406991 | NULL | MIR21 | microRNA 21 |
| 3294 | NA | 3294 | ENSG00000086696 | HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 |
| 4312 | NA | 4312 | ENSG00000196611 | MMP1 | matrix metallopeptidase 1 (interstitial collagenase) |
| 8743 | NA | 8743 | ENSG00000121858 | TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 |
| 857 | NA | 857 | ENSG00000105974 | CAV1 | caveolin 1, caveolae protein, 22kDa |
| 7422 | NA | 7422 | ENSG00000112715 | VEGFA | vascular endothelial growth factor A |
| 406992 | NA | 406992 | NULL | MIR210 | microRNA 210 |
| 4088 | NA | 4088 | ENSG00000166949 | SMAD3 | SMAD family member 3 |
| 5743 | NA | 5743 | ENSG00000073756 | PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
| 4087 | NA | 4087 | ENSG00000175387 | SMAD2 | SMAD family member 2 |
| 6772 | NA | 6772 | ENSG00000115415 | STAT1 | signal transducer and activator of transcription 1, 91kDa |
| 3065 | NA | 3065 | ENSG00000116478 | HDAC1 | histone deacetylase 1 |
| 3082 | NA | 3082 | ENSG00000019991 | HGF | hepatocyte growth factor (hepapoietin A; scatter factor) |
| 688 | NA | 688 | ENSG00000102554 | KLF5 | Kruppel-like factor 5 (intestinal) |
| 657 | NA | 657 | ENSG00000107779 | BMPR1A | bone morphogenetic protein receptor, type IA |
| 5594 | NA | 5594 | ENSG00000100030 | MAPK1 | mitogen-activated protein kinase 1 |
| 4089 | NA | 4089 | ENSG00000141646 | SMAD4 | SMAD family member 4 |
| 407009 | NA | 407009 | NULL | MIR224 | microRNA 224 |
| 4318 | NA | 4318 | ENSG00000100985 | MMP9 | matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) |
| 1236 | NA | 1236 | ENSG00000126353 | CCR7 | chemokine (C-C motif) receptor 7 |
| 4092 | NA | 4092 | ENSG00000101665 | SMAD7 | SMAD family member 7 |
| 3398 | NA | 3398 | ENSG00000115738 | ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein |
| 7046 | NA | 7046 | ENSG00000106799 | TGFBR1 | transforming growth factor, beta receptor 1 |
| 9518 | NA | 9518 | ENSG00000130513 | GDF15 | growth differentiation factor 15 |
| 10663 | NA | 10663 | ENSG00000172215 | CXCR6 | chemokine (C-X-C motif) receptor 6 |
| 7048 | NA | 7048 | ENSG00000163513 | TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) |
| 6714 | NA | 6714 | ENSG00000197122 | SRC | v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) |
| 7057 | NA | 7057 | ENSG00000137801 | THBS1 | thrombospondin 1 |
| 3662 | NA | 3662 | ENSG00000137265 | IRF4 | interferon regulatory factor 4 |
| 6696 | NA | 6696 | ENSG00000118785 | SPP1 | secreted phosphoprotein 1 |
| 3480 | NA | 3480 | ENSG00000140443 | IGF1R | insulin-like growth factor 1 receptor |
| 7076 | NA | 7076 | ENSG00000102265 | TIMP1 | TIMP metallopeptidase inhibitor 1 |
| 4313 | NA | 4313 | ENSG00000087245 | MMP2 | matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) |
| 6387 | NA | 6387 | ENSG00000107562 | CXCL12 | chemokine (C-X-C motif) ligand 12 |
| 5292 | NA | 5292 | ENSG00000137193 | PIM1 | pim-1 oncogene |
| 960 | NA | 960 | ENSG00000026508 | CD44 | CD44 molecule (Indian blood group) |
| 6774 | NA | 6774 | ENSG00000168610 | STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) |
| 7040 | NA | 7040 | ENSG00000105329 | TGFB1 | transforming growth factor, beta 1 |
| 7471 | NA | 7471 | ENSG00000125084 | WNT1 | wingless-type MMTV integration site family, member 1 |
| 4851 | NA | 4851 | ENSG00000148400 | NOTCH1 | notch 1 |
| 993 | NA | 993 | ENSG00000164045 | CDC25A | cell division cycle 25 homolog A (S. pombe) |
| 574411 | NA | 574411 | NULL | MIR451A | microRNA 451a |
| 2100 | NA | 2100 | ENSG00000140009 | ESR2 | estrogen receptor 2 (ER beta) |
| 2353 | NA | 2353 | ENSG00000170345 | FOS | FBJ murine osteosarcoma viral oncogene homolog |
| 406937 | NA | 406937 | NULL | MIR145 | microRNA 145 |
| 1956 | NA | 1956 | ENSG00000146648 | EGFR | epidermal growth factor receptor |
| 3091 | NA | 3091 | ENSG00000100644 | HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) |
| 406885 | NA | 406885 | NULL | MIRLET7C | microRNA let-7c |
| 3099 | NA | 3099 | ENSG00000159399 | HK2 | hexokinase 2 |
| 2852 | NA | 2852 | ENSG00000164850 | GPER | G protein-coupled estrogen receptor 1 |
| 2099 | NA | 2099 | ENSG00000091831 | ESR1 | estrogen receptor 1 |
| disease----Vascular Diseases----DB_ID:PA446021 | |||||
| C=357;O=56;E=2.82;R=19.84;rawP=3.09e-55;adjP=9.68e-53 | |||||
| 4318 | NA | 4318 | ENSG00000100985 | MMP9 | matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) |
| 1524 | NA | 1524 | ENSG00000168329 | CX3CR1 | chemokine (C-X3-C motif) receptor 1 |
| 1636 | NA | 1636 | ENSG00000159640 | ACE | angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 |
| 6347 | NA | 6347 | ENSG00000108691 | CCL2 | chemokine (C-C motif) ligand 2 |
| 959 | NA | 959 | ENSG00000102245 | CD40LG | CD40 ligand |
| 3791 | NA | 3791 | ENSG00000128052 | KDR | kinase insert domain receptor (a type III receptor tyrosine kinase) |
| 3552 | NA | 3552 | ENSG00000115008 | IL1A | interleukin 1, alpha |
| 5155 | NA | 5155 | ENSG00000100311 | PDGFB | platelet-derived growth factor beta polypeptide |
| 3162 | NA | 3162 | ENSG00000100292 | HMOX1 | heme oxygenase (decycling) 1 |
| 7048 | NA | 7048 | ENSG00000163513 | TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) |
| 3383 | NA | 3383 | ENSG00000090339 | ICAM1 | intercellular adhesion molecule 1 |
| 7057 | NA | 7057 | ENSG00000137801 | THBS1 | thrombospondin 1 |
| 2022 | NA | 2022 | ENSG00000106991 | ENG | endoglin |
| 240 | NA | 240 | ENSG00000012779 | ALOX5 | arachidonate 5-lipoxygenase |
| 6696 | NA | 6696 | ENSG00000118785 | SPP1 | secreted phosphoprotein 1 |
| 8600 | NA | 8600 | ENSG00000120659 | TNFSF11 | tumor necrosis factor (ligand) superfamily, member 11 |
| 7076 | NA | 7076 | ENSG00000102265 | TIMP1 | TIMP metallopeptidase inhibitor 1 |
| 8742 | NA | 8742 | ENSG00000239697 | TNFSF12 | tumor necrosis factor (ligand) superfamily, member 12 |
| 1361 | NA | 1361 | ENSG00000080618 | CPB2 | carboxypeptidase B2 (plasma) |
| 4313 | NA | 4313 | ENSG00000087245 | MMP2 | matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) |
| 348 | NA | 348 | ENSG00000130203 | APOE | apolipoprotein E |
| 1910 | NA | 1910 | ENSG00000136160 | EDNRB | endothelin receptor type B |
| 3952 | NA | 3952 | ENSG00000174697 | LEP | leptin |
| 6387 | NA | 6387 | ENSG00000107562 | CXCL12 | chemokine (C-X-C motif) ligand 12 |
| 4854 | NA | 4854 | ENSG00000074181 | NOTCH3 | notch 3 |
| 1889 | NA | 1889 | ENSG00000117298 | ECE1 | endothelin converting enzyme 1 |
| 10911 | NA | 10911 | ENSG00000049247 | UTS2 | urotensin 2 |
| 1401 | NA | 1401 | ENSG00000132693 | CRP | C-reactive protein, pentraxin-related |
| 187 | NA | 187 | NULL | APLNR | apelin receptor |
| 4846 | NA | 4846 | ENSG00000164867 | NOS3 | nitric oxide synthase 3 (endothelial cell) |
| 3156 | NA | 3156 | ENSG00000113161 | HMGCR | 3-hydroxy-3-methylglutaryl-CoA reductase |
| 7124 | NA | 7124 | ENSG00000232810 | TNF | tumor necrosis factor |
| 8862 | NA | 8862 | ENSG00000171388 | APLN | apelin |
| 5468 | NA | 5468 | ENSG00000132170 | PPARG | peroxisome proliferator-activated receptor gamma |
| 4035 | NA | 4035 | ENSG00000123384 | LRP1 | low density lipoprotein receptor-related protein 1 |
| 1906 | NA | 1906 | ENSG00000078401 | EDN1 | endothelin 1 |
| 4312 | NA | 4312 | ENSG00000196611 | MMP1 | matrix metallopeptidase 1 (interstitial collagenase) |
| 7422 | NA | 7422 | ENSG00000112715 | VEGFA | vascular endothelial growth factor A |
| 1909 | NA | 1909 | ENSG00000151617 | EDNRA | endothelin receptor type A |
| 185 | NA | 185 | ENSG00000144891 | AGTR1 | angiotensin II receptor, type 1 |
| 1535 | NA | 1535 | ENSG00000051523 | CYBA | cytochrome b-245, alpha polypeptide |
| 4314 | NA | 4314 | ENSG00000149968 | MMP3 | matrix metallopeptidase 3 (stromelysin 1, progelatinase) |
| 94 | NA | 94 | ENSG00000139567 | ACVRL1 | activin A receptor type II-like 1 |
| 5740 | NA | 5740 | ENSG00000124212 | PTGIS | prostaglandin I2 (prostacyclin) synthase |
| 3569 | NA | 3569 | ENSG00000136244 | IL6 | interleukin 6 (interferon, beta 2) |
| 7450 | NA | 7450 | ENSG00000110799 | VWF | von Willebrand factor |
| 4879 | NA | 4879 | ENSG00000120937 | NPPB | natriuretic peptide B |
| 3082 | NA | 3082 | ENSG00000019991 | HGF | hepatocyte growth factor (hepapoietin A; scatter factor) |
| 7412 | NA | 7412 | ENSG00000162692 | VCAM1 | vascular cell adhesion molecule 1 |
| 5054 | NA | 5054 | ENSG00000106366 | SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 |
| 7292 | NA | 7292 | ENSG00000117586 | TNFSF4 | tumor necrosis factor (ligand) superfamily, member 4 |
| 2982 | NA | 2982 | ENSG00000164116 | GUCY1A3 | guanylate cyclase 1, soluble, alpha 3 |
| 59272 | NA | 59272 | ENSG00000130234 | ACE2 | angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 |
| 4843 | NA | 4843 | ENSG00000007171 | NOS2 | nitric oxide synthase 2, inducible |
| 284 | NA | 284 | ENSG00000154188 | ANGPT1 | angiopoietin 1 |
| 2006 | NA | 2006 | ENSG00000049540 | ELN | elastin |
| disease----Pathologic Processes----DB_ID:PA445265 | |||||
| C=561;O=64;E=4.44;R=14.43;rawP=3.78e-54;adjP=9.47e-52 | |||||
| 3351 | NA | 3351 | ENSG00000135312 | HTR1B | 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled |
| 6347 | NA | 6347 | ENSG00000108691 | CCL2 | chemokine (C-C motif) ligand 2 |
| 3791 | NA | 3791 | ENSG00000128052 | KDR | kinase insert domain receptor (a type III receptor tyrosine kinase) |
| 1950 | NA | 1950 | ENSG00000138798 | EGF | epidermal growth factor |
| 3596 | NA | 3596 | ENSG00000169194 | IL13 | interleukin 13 |
| 7157 | NA | 7157 | ENSG00000141510 | TP53 | tumor protein p53 |
| 6648 | NA | 6648 | ENSG00000112096 | SOD2 | superoxide dismutase 2, mitochondrial |
| 3552 | NA | 3552 | ENSG00000115008 | IL1A | interleukin 1, alpha |
| 5155 | NA | 5155 | ENSG00000100311 | PDGFB | platelet-derived growth factor beta polypeptide |
| 3162 | NA | 3162 | ENSG00000100292 | HMOX1 | heme oxygenase (decycling) 1 |
| 3371 | NA | 3371 | ENSG00000041982 | TNC | tenascin C |
| 2022 | NA | 2022 | ENSG00000106991 | ENG | endoglin |
| 595 | NA | 595 | ENSG00000110092 | CCND1 | cyclin D1 |
| 1490 | NA | 1490 | ENSG00000118523 | CTGF | connective tissue growth factor |
| 3119 | NA | 3119 | ENSG00000179344 | HLA-DQB1 | major histocompatibility complex, class II, DQ beta 1 |
| 8742 | NA | 8742 | ENSG00000239697 | TNFSF12 | tumor necrosis factor (ligand) superfamily, member 12 |
| 1027 | NA | 1027 | ENSG00000111276 | CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) |
| 1401 | NA | 1401 | ENSG00000132693 | CRP | C-reactive protein, pentraxin-related |
| 1545 | NA | 1545 | ENSG00000138061 | CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
| 6275 | NA | 6275 | ENSG00000196154 | S100A4 | S100 calcium binding protein A4 |
| 406991 | NA | 406991 | NULL | MIR21 | microRNA 21 |
| 4312 | NA | 4312 | ENSG00000196611 | MMP1 | matrix metallopeptidase 1 (interstitial collagenase) |
| 7422 | NA | 7422 | ENSG00000112715 | VEGFA | vascular endothelial growth factor A |
| 51099 | NA | 51099 | ENSG00000011198 | ABHD5 | abhydrolase domain containing 5 |
| 5743 | NA | 5743 | ENSG00000073756 | PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
| 4314 | NA | 4314 | ENSG00000149968 | MMP3 | matrix metallopeptidase 3 (stromelysin 1, progelatinase) |
| 4128 | NA | 4128 | ENSG00000189221 | MAOA | monoamine oxidase A |
| 4879 | NA | 4879 | ENSG00000120937 | NPPB | natriuretic peptide B |
| 5054 | NA | 5054 | ENSG00000106366 | SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 |
| 7292 | NA | 7292 | ENSG00000117586 | TNFSF4 | tumor necrosis factor (ligand) superfamily, member 4 |
| 284 | NA | 284 | ENSG00000154188 | ANGPT1 | angiopoietin 1 |
| 4318 | NA | 4318 | ENSG00000100985 | MMP9 | matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) |
| 6331 | NA | 6331 | ENSG00000183873 | SCN5A | sodium channel, voltage-gated, type V, alpha subunit |
| 1636 | NA | 1636 | ENSG00000159640 | ACE | angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 |
| 1236 | NA | 1236 | ENSG00000126353 | CCR7 | chemokine (C-C motif) receptor 7 |
| 1524 | NA | 1524 | ENSG00000168329 | CX3CR1 | chemokine (C-X3-C motif) receptor 1 |
| 7046 | NA | 7046 | ENSG00000106799 | TGFBR1 | transforming growth factor, beta receptor 1 |
| 7048 | NA | 7048 | ENSG00000163513 | TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) |
| 10666 | NA | 10666 | ENSG00000150637 | CD226 | CD226 molecule |
| 3115 | NA | 3115 | ENSG00000223865 | HLA-DPB1 | major histocompatibility complex, class II, DP beta 1 |
| 3383 | NA | 3383 | ENSG00000090339 | ICAM1 | intercellular adhesion molecule 1 |
| 7057 | NA | 7057 | ENSG00000137801 | THBS1 | thrombospondin 1 |
| 3123 | NA | 3123 | ENSG00000196126 | HLA-DRB1 | major histocompatibility complex, class II, DR beta 1 |
| 6696 | NA | 6696 | ENSG00000118785 | SPP1 | secreted phosphoprotein 1 |
| 3662 | NA | 3662 | ENSG00000137265 | IRF4 | interferon regulatory factor 4 |
| 7076 | NA | 7076 | ENSG00000102265 | TIMP1 | TIMP metallopeptidase inhibitor 1 |
| 4313 | NA | 4313 | ENSG00000087245 | MMP2 | matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) |
| 348 | NA | 348 | ENSG00000130203 | APOE | apolipoprotein E |
| 6387 | NA | 6387 | ENSG00000107562 | CXCL12 | chemokine (C-X-C motif) ligand 12 |
| 960 | NA | 960 | ENSG00000026508 | CD44 | CD44 molecule (Indian blood group) |
| 4846 | NA | 4846 | ENSG00000164867 | NOS3 | nitric oxide synthase 3 (endothelial cell) |
| 7040 | NA | 7040 | ENSG00000105329 | TGFB1 | transforming growth factor, beta 1 |
| 7124 | NA | 7124 | ENSG00000232810 | TNF | tumor necrosis factor |
| 7166 | NA | 7166 | ENSG00000129167 | TPH1 | tryptophan hydroxylase 1 |
| 1906 | NA | 1906 | ENSG00000078401 | EDN1 | endothelin 1 |
| 6262 | NA | 6262 | ENSG00000198626 | RYR2 | ryanodine receptor 2 (cardiac) |
| 84735 | NA | 84735 | ENSG00000150656 | CNDP1 | carnosine dipeptidase 1 (metallopeptidase M20 family) |
| 3554 | NA | 3554 | ENSG00000115594 | IL1R1 | interleukin 1 receptor, type I |
| 185 | NA | 185 | ENSG00000144891 | AGTR1 | angiotensin II receptor, type 1 |
| 5265 | NA | 5265 | ENSG00000197249 | SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 |
| 3091 | NA | 3091 | ENSG00000100644 | HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) |
| 6532 | NA | 6532 | ENSG00000108576 | SLC6A4 | solute carrier family 6 (neurotransmitter transporter, serotonin), member 4 |
| 3569 | NA | 3569 | ENSG00000136244 | IL6 | interleukin 6 (interferon, beta 2) |
| 4843 | NA | 4843 | ENSG00000007171 | NOS2 | nitric oxide synthase 2, inducible |
| disease----Neoplasms----DB_ID:PA445062 | |||||
| C=854;O=73;E=6.75;R=10.81;rawP=6.77e-53;adjP=1.41e-50 | |||||
| 3292 | NA | 3292 | ENSG00000108786 | HSD17B1 | hydroxysteroid (17-beta) dehydrogenase 1 |
| 1588 | NA | 1588 | ENSG00000137869 | CYP19A1 | cytochrome P450, family 19, subfamily A, polypeptide 1 |
| 3397 | NA | 3397 | ENSG00000125968 | ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
| 407019 | NA | 407019 | NULL | MIR27B | microRNA 27b |
| 3791 | NA | 3791 | ENSG00000128052 | KDR | kinase insert domain receptor (a type III receptor tyrosine kinase) |
| 5037 | NA | 5037 | ENSG00000089220 | PEBP1 | phosphatidylethanolamine binding protein 1 |
| 1950 | NA | 1950 | ENSG00000138798 | EGF | epidermal growth factor |
| 7157 | NA | 7157 | ENSG00000141510 | TP53 | tumor protein p53 |
| 6648 | NA | 6648 | ENSG00000112096 | SOD2 | superoxide dismutase 2, mitochondrial |
| 331 | NA | 331 | ENSG00000101966 | XIAP | X-linked inhibitor of apoptosis |
| 5157 | NA | 5157 | ENSG00000104213 | PDGFRL | platelet-derived growth factor receptor-like |
| 5460 | NA | 5460 | ENSG00000204531 | POU5F1 | POU class 5 homeobox 1 |
| 5155 | NA | 5155 | ENSG00000100311 | PDGFB | platelet-derived growth factor beta polypeptide |
| 5156 | NA | 5156 | ENSG00000134853 | PDGFRA | platelet-derived growth factor receptor, alpha polypeptide |
| 3371 | NA | 3371 | ENSG00000041982 | TNC | tenascin C |
| 7474 | NA | 7474 | ENSG00000114251 | WNT5A | wingless-type MMTV integration site family, member 5A |
| 5154 | NA | 5154 | ENSG00000197461 | PDGFA | platelet-derived growth factor alpha polypeptide |
| 595 | NA | 595 | ENSG00000110092 | CCND1 | cyclin D1 |
| 1499 | NA | 1499 | ENSG00000168036 | CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa |
| 1027 | NA | 1027 | ENSG00000111276 | CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) |
| 407018 | NA | 407018 | NULL | MIR27A | microRNA 27a |
| 841 | NA | 841 | ENSG00000064012 | CASP8 | caspase 8, apoptosis-related cysteine peptidase |
| 9166 | NA | 9166 | ENSG00000147654 | EBAG9 | estrogen receptor binding site associated, antigen, 9 |
| 1545 | NA | 1545 | ENSG00000138061 | CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
| 406881 | NA | 406881 | NULL | MIRLET7A1 | microRNA let-7a-1 |
| 406952 | NA | 406952 | NULL | MIR17 | microRNA 17 |
| 207 | NA | 207 | ENSG00000142208 | AKT1 | v-akt murine thymoma viral oncogene homolog 1 |
| 6275 | NA | 6275 | ENSG00000196154 | S100A4 | S100 calcium binding protein A4 |
| 3309 | NA | 3309 | ENSG00000044574 | HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) |
| 406991 | NA | 406991 | NULL | MIR21 | microRNA 21 |
| 3294 | NA | 3294 | ENSG00000086696 | HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 |
| 4312 | NA | 4312 | ENSG00000196611 | MMP1 | matrix metallopeptidase 1 (interstitial collagenase) |
| 8743 | NA | 8743 | ENSG00000121858 | TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 |
| 857 | NA | 857 | ENSG00000105974 | CAV1 | caveolin 1, caveolae protein, 22kDa |
| 7422 | NA | 7422 | ENSG00000112715 | VEGFA | vascular endothelial growth factor A |
| 406992 | NA | 406992 | NULL | MIR210 | microRNA 210 |
| 5743 | NA | 5743 | ENSG00000073756 | PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
| 3082 | NA | 3082 | ENSG00000019991 | HGF | hepatocyte growth factor (hepapoietin A; scatter factor) |
| 688 | NA | 688 | ENSG00000102554 | KLF5 | Kruppel-like factor 5 (intestinal) |
| 4089 | NA | 4089 | ENSG00000141646 | SMAD4 | SMAD family member 4 |
| 407009 | NA | 407009 | NULL | MIR224 | microRNA 224 |
| 6715 | NA | 6715 | ENSG00000145545 | SRD5A1 | steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) |
| 4318 | NA | 4318 | ENSG00000100985 | MMP9 | matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) |
| 1236 | NA | 1236 | ENSG00000126353 | CCR7 | chemokine (C-C motif) receptor 7 |
| 4092 | NA | 4092 | ENSG00000101665 | SMAD7 | SMAD family member 7 |
| 3398 | NA | 3398 | ENSG00000115738 | ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein |
| 7046 | NA | 7046 | ENSG00000106799 | TGFBR1 | transforming growth factor, beta receptor 1 |
| 9518 | NA | 9518 | ENSG00000130513 | GDF15 | growth differentiation factor 15 |
| 7048 | NA | 7048 | ENSG00000163513 | TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) |
| 6714 | NA | 6714 | ENSG00000197122 | SRC | v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) |
| 55107 | NA | 55107 | ENSG00000131620 | ANO1 | anoctamin 1, calcium activated chloride channel |
| 60500 | NA | 60500 | NULL | BRCA3 | breast cancer 3 |
| 7057 | NA | 7057 | ENSG00000137801 | THBS1 | thrombospondin 1 |
| 3662 | NA | 3662 | ENSG00000137265 | IRF4 | interferon regulatory factor 4 |
| 6696 | NA | 6696 | ENSG00000118785 | SPP1 | secreted phosphoprotein 1 |
| 3480 | NA | 3480 | ENSG00000140443 | IGF1R | insulin-like growth factor 1 receptor |
| 7076 | NA | 7076 | ENSG00000102265 | TIMP1 | TIMP metallopeptidase inhibitor 1 |
| 4313 | NA | 4313 | ENSG00000087245 | MMP2 | matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) |
| 6387 | NA | 6387 | ENSG00000107562 | CXCL12 | chemokine (C-X-C motif) ligand 12 |
| 5292 | NA | 5292 | ENSG00000137193 | PIM1 | pim-1 oncogene |
| 960 | NA | 960 | ENSG00000026508 | CD44 | CD44 molecule (Indian blood group) |
| 6774 | NA | 6774 | ENSG00000168610 | STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) |
| 7471 | NA | 7471 | ENSG00000125084 | WNT1 | wingless-type MMTV integration site family, member 1 |
| 4851 | NA | 4851 | ENSG00000148400 | NOTCH1 | notch 1 |
| 574411 | NA | 574411 | NULL | MIR451A | microRNA 451a |
| 2100 | NA | 2100 | ENSG00000140009 | ESR2 | estrogen receptor 2 (ER beta) |
| 406937 | NA | 406937 | NULL | MIR145 | microRNA 145 |
| 1956 | NA | 1956 | ENSG00000146648 | EGFR | epidermal growth factor receptor |
| 406885 | NA | 406885 | NULL | MIRLET7C | microRNA let-7c |
| 3091 | NA | 3091 | ENSG00000100644 | HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) |
| 3099 | NA | 3099 | ENSG00000159399 | HK2 | hexokinase 2 |
| 2852 | NA | 2852 | ENSG00000164850 | GPER | G protein-coupled estrogen receptor 1 |
| 2099 | NA | 2099 | ENSG00000091831 | ESR1 | estrogen receptor 1 |
| disease----Inflammation----DB_ID:PA444620 | |||||
| C=435;O=54;E=3.44;R=15.70;rawP=1.30e-47;adjP=2.33e-45 | |||||
| 4318 | NA | 4318 | ENSG00000100985 | MMP9 | matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) |
| 1524 | NA | 1524 | ENSG00000168329 | CX3CR1 | chemokine (C-X3-C motif) receptor 1 |
| 6347 | NA | 6347 | ENSG00000108691 | CCL2 | chemokine (C-C motif) ligand 2 |
| 959 | NA | 959 | ENSG00000102245 | CD40LG | CD40 ligand |
| 3596 | NA | 3596 | ENSG00000169194 | IL13 | interleukin 13 |
| 9518 | NA | 9518 | ENSG00000130513 | GDF15 | growth differentiation factor 15 |
| 10663 | NA | 10663 | ENSG00000172215 | CXCR6 | chemokine (C-X-C motif) receptor 6 |
| 3552 | NA | 3552 | ENSG00000115008 | IL1A | interleukin 1, alpha |
| 3162 | NA | 3162 | ENSG00000100292 | HMOX1 | heme oxygenase (decycling) 1 |
| 3371 | NA | 3371 | ENSG00000041982 | TNC | tenascin C |
| 3383 | NA | 3383 | ENSG00000090339 | ICAM1 | intercellular adhesion molecule 1 |
| 240 | NA | 240 | ENSG00000012779 | ALOX5 | arachidonate 5-lipoxygenase |
| 6696 | NA | 6696 | ENSG00000118785 | SPP1 | secreted phosphoprotein 1 |
| 8600 | NA | 8600 | ENSG00000120659 | TNFSF11 | tumor necrosis factor (ligand) superfamily, member 11 |
| 1230 | NA | 1230 | ENSG00000163823 | CCR1 | chemokine (C-C motif) receptor 1 |
| 7076 | NA | 7076 | ENSG00000102265 | TIMP1 | TIMP metallopeptidase inhibitor 1 |
| 8742 | NA | 8742 | ENSG00000239697 | TNFSF12 | tumor necrosis factor (ligand) superfamily, member 12 |
| 1361 | NA | 1361 | ENSG00000080618 | CPB2 | carboxypeptidase B2 (plasma) |
| 4313 | NA | 4313 | ENSG00000087245 | MMP2 | matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) |
| 135 | NA | 135 | ENSG00000128271 | ADORA2A | adenosine A2a receptor |
| 3952 | NA | 3952 | ENSG00000174697 | LEP | leptin |
| 9034 | NA | 9034 | ENSG00000121797 | CCRL2 | chemokine (C-C motif) receptor-like 2 |
| 6387 | NA | 6387 | ENSG00000107562 | CXCL12 | chemokine (C-X-C motif) ligand 12 |
| 6863 | NA | 6863 | ENSG00000006128 | TAC1 | tachykinin, precursor 1 |
| 6348 | NA | 6348 | ENSG00000006075 | CCL3 | chemokine (C-C motif) ligand 3 |
| 6774 | NA | 6774 | ENSG00000168610 | STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) |
| 1401 | NA | 1401 | ENSG00000132693 | CRP | C-reactive protein, pentraxin-related |
| 1843 | NA | 1843 | ENSG00000120129 | DUSP1 | dual specificity phosphatase 1 |
| 4846 | NA | 4846 | ENSG00000164867 | NOS3 | nitric oxide synthase 3 (endothelial cell) |
| 7124 | NA | 7124 | ENSG00000232810 | TNF | tumor necrosis factor |
| 7040 | NA | 7040 | ENSG00000105329 | TGFB1 | transforming growth factor, beta 1 |
| 718 | NA | 718 | ENSG00000125730 | C3 | complement component 3 |
| 5468 | NA | 5468 | ENSG00000132170 | PPARG | peroxisome proliferator-activated receptor gamma |
| 1906 | NA | 1906 | ENSG00000078401 | EDN1 | endothelin 1 |
| 4312 | NA | 4312 | ENSG00000196611 | MMP1 | matrix metallopeptidase 1 (interstitial collagenase) |
| 7422 | NA | 7422 | ENSG00000112715 | VEGFA | vascular endothelial growth factor A |
| 3554 | NA | 3554 | ENSG00000115594 | IL1R1 | interleukin 1 receptor, type I |
| 1051 | NA | 1051 | ENSG00000172216 | CEBPB | CCAAT/enhancer binding protein (C/EBP), beta |
| 5743 | NA | 5743 | ENSG00000073756 | PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
| 1907 | NA | 1907 | ENSG00000127129 | EDN2 | endothelin 2 |
| 3627 | NA | 3627 | ENSG00000169245 | CXCL10 | chemokine (C-X-C motif) ligand 10 |
| 5265 | NA | 5265 | ENSG00000197249 | SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 |
| 4314 | NA | 4314 | ENSG00000149968 | MMP3 | matrix metallopeptidase 3 (stromelysin 1, progelatinase) |
| 3091 | NA | 3091 | ENSG00000100644 | HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) |
| 3569 | NA | 3569 | ENSG00000136244 | IL6 | interleukin 6 (interferon, beta 2) |
| 961 | NA | 961 | ENSG00000196776 | CD47 | CD47 molecule |
| 6772 | NA | 6772 | ENSG00000115415 | STAT1 | signal transducer and activator of transcription 1, 91kDa |
| 5054 | NA | 5054 | ENSG00000106366 | SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 |
| 7412 | NA | 7412 | ENSG00000162692 | VCAM1 | vascular cell adhesion molecule 1 |
| 7292 | NA | 7292 | ENSG00000117586 | TNFSF4 | tumor necrosis factor (ligand) superfamily, member 4 |
| 2150 | NA | 2150 | ENSG00000164251 | F2RL1 | coagulation factor II (thrombin) receptor-like 1 |
| 4843 | NA | 4843 | ENSG00000007171 | NOS2 | nitric oxide synthase 2, inducible |
| 284 | NA | 284 | ENSG00000154188 | ANGPT1 | angiopoietin 1 |
| 3598 | NA | 3598 | ENSG00000123496 | IL13RA2 | interleukin 13 receptor, alpha 2 |
| disease----Cardiovascular Diseases----DB_ID:PA443635 | |||||
| C=425;O=53;E=3.36;R=15.77;rawP=7.79e-47;adjP=1.22e-44 | |||||
| 4318 | NA | 4318 | ENSG00000100985 | MMP9 | matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) |
| 6331 | NA | 6331 | ENSG00000183873 | SCN5A | sodium channel, voltage-gated, type V, alpha subunit |
| 1524 | NA | 1524 | ENSG00000168329 | CX3CR1 | chemokine (C-X3-C motif) receptor 1 |
| 1636 | NA | 1636 | ENSG00000159640 | ACE | angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 |
| 6347 | NA | 6347 | ENSG00000108691 | CCL2 | chemokine (C-C motif) ligand 2 |
| 959 | NA | 959 | ENSG00000102245 | CD40LG | CD40 ligand |
| 3552 | NA | 3552 | ENSG00000115008 | IL1A | interleukin 1, alpha |
| 3162 | NA | 3162 | ENSG00000100292 | HMOX1 | heme oxygenase (decycling) 1 |
| 7048 | NA | 7048 | ENSG00000163513 | TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) |
| 3383 | NA | 3383 | ENSG00000090339 | ICAM1 | intercellular adhesion molecule 1 |
| 7057 | NA | 7057 | ENSG00000137801 | THBS1 | thrombospondin 1 |
| 2022 | NA | 2022 | ENSG00000106991 | ENG | endoglin |
| 240 | NA | 240 | ENSG00000012779 | ALOX5 | arachidonate 5-lipoxygenase |
| 7076 | NA | 7076 | ENSG00000102265 | TIMP1 | TIMP metallopeptidase inhibitor 1 |
| 775 | NA | 775 | ENSG00000151067 | CACNA1C | calcium channel, voltage-dependent, L type, alpha 1C subunit |
| 8742 | NA | 8742 | ENSG00000239697 | TNFSF12 | tumor necrosis factor (ligand) superfamily, member 12 |
| 1361 | NA | 1361 | ENSG00000080618 | CPB2 | carboxypeptidase B2 (plasma) |
| 4313 | NA | 4313 | ENSG00000087245 | MMP2 | matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) |
| 348 | NA | 348 | ENSG00000130203 | APOE | apolipoprotein E |
| 1910 | NA | 1910 | ENSG00000136160 | EDNRB | endothelin receptor type B |
| 3952 | NA | 3952 | ENSG00000174697 | LEP | leptin |
| 6387 | NA | 6387 | ENSG00000107562 | CXCL12 | chemokine (C-X-C motif) ligand 12 |
| 4854 | NA | 4854 | ENSG00000074181 | NOTCH3 | notch 3 |
| 1889 | NA | 1889 | ENSG00000117298 | ECE1 | endothelin converting enzyme 1 |
| 10911 | NA | 10911 | ENSG00000049247 | UTS2 | urotensin 2 |
| 1401 | NA | 1401 | ENSG00000132693 | CRP | C-reactive protein, pentraxin-related |
| 187 | NA | 187 | NULL | APLNR | apelin receptor |
| 4846 | NA | 4846 | ENSG00000164867 | NOS3 | nitric oxide synthase 3 (endothelial cell) |
| 3156 | NA | 3156 | ENSG00000113161 | HMGCR | 3-hydroxy-3-methylglutaryl-CoA reductase |
| 7124 | NA | 7124 | ENSG00000232810 | TNF | tumor necrosis factor |
| 8862 | NA | 8862 | ENSG00000171388 | APLN | apelin |
| 5468 | NA | 5468 | ENSG00000132170 | PPARG | peroxisome proliferator-activated receptor gamma |
| 1906 | NA | 1906 | ENSG00000078401 | EDN1 | endothelin 1 |
| 4312 | NA | 4312 | ENSG00000196611 | MMP1 | matrix metallopeptidase 1 (interstitial collagenase) |
| 6262 | NA | 6262 | ENSG00000198626 | RYR2 | ryanodine receptor 2 (cardiac) |
| 7422 | NA | 7422 | ENSG00000112715 | VEGFA | vascular endothelial growth factor A |
| 1909 | NA | 1909 | ENSG00000151617 | EDNRA | endothelin receptor type A |
| 185 | NA | 185 | ENSG00000144891 | AGTR1 | angiotensin II receptor, type 1 |
| 4314 | NA | 4314 | ENSG00000149968 | MMP3 | matrix metallopeptidase 3 (stromelysin 1, progelatinase) |
| 1535 | NA | 1535 | ENSG00000051523 | CYBA | cytochrome b-245, alpha polypeptide |
| 94 | NA | 94 | ENSG00000139567 | ACVRL1 | activin A receptor type II-like 1 |
| 5740 | NA | 5740 | ENSG00000124212 | PTGIS | prostaglandin I2 (prostacyclin) synthase |
| 3984 | NA | 3984 | ENSG00000106683 | LIMK1 | LIM domain kinase 1 |
| 3569 | NA | 3569 | ENSG00000136244 | IL6 | interleukin 6 (interferon, beta 2) |
| 7450 | NA | 7450 | ENSG00000110799 | VWF | von Willebrand factor |
| 4879 | NA | 4879 | ENSG00000120937 | NPPB | natriuretic peptide B |
| 3082 | NA | 3082 | ENSG00000019991 | HGF | hepatocyte growth factor (hepapoietin A; scatter factor) |
| 7412 | NA | 7412 | ENSG00000162692 | VCAM1 | vascular cell adhesion molecule 1 |
| 5054 | NA | 5054 | ENSG00000106366 | SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 |
| 7292 | NA | 7292 | ENSG00000117586 | TNFSF4 | tumor necrosis factor (ligand) superfamily, member 4 |
| 59272 | NA | 59272 | ENSG00000130234 | ACE2 | angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 |
| 284 | NA | 284 | ENSG00000154188 | ANGPT1 | angiopoietin 1 |
| 2006 | NA | 2006 | ENSG00000049540 | ELN | elastin |
| disease----Hypertension----DB_ID:PA444552 | |||||
| C=227;O=43;E=1.79;R=23.96;rawP=3.63e-46;adjP=5.05e-44 | |||||
| 659 | NA | 659 | ENSG00000204217 | BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) |
| 1908 | NA | 1908 | ENSG00000124205 | EDN3 | endothelin 3 |
| 1636 | NA | 1636 | ENSG00000159640 | ACE | angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 |
| 3162 | NA | 3162 | ENSG00000100292 | HMOX1 | heme oxygenase (decycling) 1 |
| 2022 | NA | 2022 | ENSG00000106991 | ENG | endoglin |
| 7076 | NA | 7076 | ENSG00000102265 | TIMP1 | TIMP metallopeptidase inhibitor 1 |
| 1490 | NA | 1490 | ENSG00000118523 | CTGF | connective tissue growth factor |
| 5592 | NA | 5592 | ENSG00000185532 | PRKG1 | protein kinase, cGMP-dependent, type I |
| 348 | NA | 348 | ENSG00000130203 | APOE | apolipoprotein E |
| 1910 | NA | 1910 | ENSG00000136160 | EDNRB | endothelin receptor type B |
| 3952 | NA | 3952 | ENSG00000174697 | LEP | leptin |
| 4854 | NA | 4854 | ENSG00000074181 | NOTCH3 | notch 3 |
| 1889 | NA | 1889 | ENSG00000117298 | ECE1 | endothelin converting enzyme 1 |
| 10911 | NA | 10911 | ENSG00000049247 | UTS2 | urotensin 2 |
| 846 | NA | 846 | ENSG00000036828 | CASR | calcium-sensing receptor |
| 1401 | NA | 1401 | ENSG00000132693 | CRP | C-reactive protein, pentraxin-related |
| 9475 | NA | 9475 | ENSG00000134318 | ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 |
| 187 | NA | 187 | NULL | APLNR | apelin receptor |
| 4846 | NA | 4846 | ENSG00000164867 | NOS3 | nitric oxide synthase 3 (endothelial cell) |
| 7040 | NA | 7040 | ENSG00000105329 | TGFB1 | transforming growth factor, beta 1 |
| 8862 | NA | 8862 | ENSG00000171388 | APLN | apelin |
| 5468 | NA | 5468 | ENSG00000132170 | PPARG | peroxisome proliferator-activated receptor gamma |
| 1906 | NA | 1906 | ENSG00000078401 | EDN1 | endothelin 1 |
| 3741 | NA | 3741 | ENSG00000130037 | KCNA5 | potassium voltage-gated channel, shaker-related subfamily, member 5 |
| 1909 | NA | 1909 | ENSG00000151617 | EDNRA | endothelin receptor type A |
| 1907 | NA | 1907 | ENSG00000127129 | EDN2 | endothelin 2 |
| 185 | NA | 185 | ENSG00000144891 | AGTR1 | angiotensin II receptor, type 1 |
| 1535 | NA | 1535 | ENSG00000051523 | CYBA | cytochrome b-245, alpha polypeptide |
| 4314 | NA | 4314 | ENSG00000149968 | MMP3 | matrix metallopeptidase 3 (stromelysin 1, progelatinase) |
| 94 | NA | 94 | ENSG00000139567 | ACVRL1 | activin A receptor type II-like 1 |
| 5740 | NA | 5740 | ENSG00000124212 | PTGIS | prostaglandin I2 (prostacyclin) synthase |
| 3569 | NA | 3569 | ENSG00000136244 | IL6 | interleukin 6 (interferon, beta 2) |
| 7225 | NA | 7225 | ENSG00000137672 | TRPC6 | transient receptor potential cation channel, subfamily C, member 6 |
| 4879 | NA | 4879 | ENSG00000120937 | NPPB | natriuretic peptide B |
| 5054 | NA | 5054 | ENSG00000106366 | SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 |
| 7054 | NA | 7054 | ENSG00000180176 | TH | tyrosine hydroxylase |
| 6093 | NA | 6093 | ENSG00000067900 | ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 |
| 2837 | NA | 2837 | ENSG00000181408 | UTS2R | urotensin 2 receptor |
| 10891 | NA | 10891 | ENSG00000109819 | PPARGC1A | peroxisome proliferator-activated receptor gamma, coactivator 1 alpha |
| 2982 | NA | 2982 | ENSG00000164116 | GUCY1A3 | guanylate cyclase 1, soluble, alpha 3 |
| 7222 | NA | 7222 | ENSG00000138741 | TRPC3 | transient receptor potential cation channel, subfamily C, member 3 |
| 59272 | NA | 59272 | ENSG00000130234 | ACE2 | angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 |
| 2006 | NA | 2006 | ENSG00000049540 | ELN | elastin |
| disease----Bone Neoplasms----DB_ID:PA443538 | |||||
| C=136;O=36;E=1.08;R=33.48;rawP=1.68e-44;adjP=2.11e-42 | |||||
| 4318 | NA | 4318 | ENSG00000100985 | MMP9 | matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) |
| 659 | NA | 659 | ENSG00000204217 | BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) |
| 6347 | NA | 6347 | ENSG00000108691 | CCL2 | chemokine (C-C motif) ligand 2 |
| 27302 | NA | 27302 | ENSG00000163217 | BMP10 | bone morphogenetic protein 10 |
| 5037 | NA | 5037 | ENSG00000089220 | PEBP1 | phosphatidylethanolamine binding protein 1 |
| 7157 | NA | 7157 | ENSG00000141510 | TP53 | tumor protein p53 |
| 7046 | NA | 7046 | ENSG00000106799 | TGFBR1 | transforming growth factor, beta receptor 1 |
| 9518 | NA | 9518 | ENSG00000130513 | GDF15 | growth differentiation factor 15 |
| 4090 | NA | 4090 | ENSG00000113658 | SMAD5 | SMAD family member 5 |
| 10663 | NA | 10663 | ENSG00000172215 | CXCR6 | chemokine (C-X-C motif) receptor 6 |
| 5156 | NA | 5156 | ENSG00000134853 | PDGFRA | platelet-derived growth factor receptor, alpha polypeptide |
| 3037 | NA | 3037 | ENSG00000170961 | HAS2 | hyaluronan synthase 2 |
| 7474 | NA | 7474 | ENSG00000114251 | WNT5A | wingless-type MMTV integration site family, member 5A |
| 650 | NA | 650 | ENSG00000125845 | BMP2 | bone morphogenetic protein 2 |
| 595 | NA | 595 | ENSG00000110092 | CCND1 | cyclin D1 |
| 6696 | NA | 6696 | ENSG00000118785 | SPP1 | secreted phosphoprotein 1 |
| 8600 | NA | 8600 | ENSG00000120659 | TNFSF11 | tumor necrosis factor (ligand) superfamily, member 11 |
| 3480 | NA | 3480 | ENSG00000140443 | IGF1R | insulin-like growth factor 1 receptor |
| 1490 | NA | 1490 | ENSG00000118523 | CTGF | connective tissue growth factor |
| 4313 | NA | 4313 | ENSG00000087245 | MMP2 | matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) |
| 51517 | NA | 51517 | ENSG00000213672 | NCKIPSD | NCK interacting protein with SH3 domain |
| 2658 | NA | 2658 | ENSG00000128802 | GDF2 | growth differentiation factor 2 |
| 6387 | NA | 6387 | ENSG00000107562 | CXCL12 | chemokine (C-X-C motif) ligand 12 |
| 6774 | NA | 6774 | ENSG00000168610 | STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) |
| 26585 | NA | 26585 | ENSG00000166923 | GREM1 | gremlin 1 |
| 4093 | NA | 4093 | ENSG00000120693 | SMAD9 | SMAD family member 9 |
| 207 | NA | 207 | ENSG00000142208 | AKT1 | v-akt murine thymoma viral oncogene homolog 1 |
| 4312 | NA | 4312 | ENSG00000196611 | MMP1 | matrix metallopeptidase 1 (interstitial collagenase) |
| 7422 | NA | 7422 | ENSG00000112715 | VEGFA | vascular endothelial growth factor A |
| 4087 | NA | 4087 | ENSG00000175387 | SMAD2 | SMAD family member 2 |
| 3091 | NA | 3091 | ENSG00000100644 | HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) |
| 652 | NA | 652 | ENSG00000125378 | BMP4 | bone morphogenetic protein 4 |
| 657 | NA | 657 | ENSG00000107779 | BMPR1A | bone morphogenetic protein receptor, type IA |
| 4086 | NA | 4086 | ENSG00000170365 | SMAD1 | SMAD family member 1 |
| 4089 | NA | 4089 | ENSG00000141646 | SMAD4 | SMAD family member 4 |
| 658 | NA | 658 | ENSG00000138696 | BMPR1B | bone morphogenetic protein receptor, type IB |