DegronMD

Uniprot ID: P35968

Source protein: Vascular endothelial growth factor receptor 2

Source gene: KDR

Class: CBL_MET

Location: 120:122

E3 ligase: CBL

DEGRON score: 0.5317

ASA_SCORE: 108.7

COIL: 0.946

CONS_SCORE: 0.4781

DSS_SCORE: 0.0252

HELIX: 0.0193

FCONS_SCORE: 1.1164

RIG_SCORE: 0.9178

Degron related mutations and impact score

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.Y115D	TCGA-61-1911	OV	TCGA	DYR	CBL_MET	0.1944
p.Y115D	DO28392	OV	ICGC	DYR	CBL_MET	0.1944
p.Y121C	TCGA-CA-6717	COAD	TCGA	DYR	CBL_MET	0.8198
p.Y121C	DO8264	COAD	ICGC	DYR	CBL_MET	0.8198
p.S112L	TCGA-KK-A59V	PRAD	TCGA	DYR	CBL_MET	0.1111
p.S112L	DO51346	PRAD	ICGC	DYR	CBL_MET	0.1111
p.D131A	DO8264	COAD	ICGC	DYR	CBL_MET	0.0833
p.Q119K	DO229025	LICA	ICGC	DYR	CBL_MET	0.3056
p.A127D	DO229045	LICA	ICGC	DYR	CBL_MET	0.1944

Drug responses associated with KDR mutations

Sample	Cancer	Mutation (In Degron?)	Dataset	Drug	IC50
SIDM00926	UNCLASSIFIED\|lung_NSCLC_not_specified	p.G1145R (No)	GDSC	Ponatinib	16.0729
SIDM00926	UNCLASSIFIED\|lung_NSCLC_not_specified	p.G1145R (No)	GDSC	Cabozantinib	36.0932
SIDM00926	UNCLASSIFIED\|lung_NSCLC_not_specified	p.G1145R (No)	GDSC	Linifanib	22.6549
SIDM00926	UNCLASSIFIED\|lung_NSCLC_not_specified	p.G1145R (No)	GDSC	Foretinib	2.9466
SIDM00926	UNCLASSIFIED\|lung_NSCLC_not_specified	p.G1145R (No)	GDSC	Tivozanib	3.0227
SIDM00926	UNCLASSIFIED\|lung_NSCLC_not_specified	p.G1145R (No)	GDSC	Brivanib, BMS-540215	565.6622
SIDM00926	UNCLASSIFIED\|lung_NSCLC_not_specified	p.G1145R (No)	GDSC	BIBF-1120	417.0341
SIDM00926	UNCLASSIFIED\|lung_NSCLC_not_specified	p.G1145R (No)	GDSC	Axitinib	62.1618
SIDM00926	UNCLASSIFIED\|lung_NSCLC_not_specified	p.G1145R (No)	GDSC	Motesanib	51.6911
SIDM00747	LUAD\|lung_NSCLC_adenocarcinoma	p.P91fs*3 (No)	GDSC	Ponatinib	11.8907
SIDM00747	LUAD\|lung_NSCLC_adenocarcinoma	p.P91fs*3 (No)	GDSC	Cabozantinib	52.3382
SIDM00747	LUAD\|lung_NSCLC_adenocarcinoma	p.P91fs*3 (No)	GDSC	Linifanib	18.2331
SIDM00747	LUAD\|lung_NSCLC_adenocarcinoma	p.P91fs*3 (No)	GDSC	Foretinib	3.3984
SIDM00747	LUAD\|lung_NSCLC_adenocarcinoma	p.P91fs*3 (No)	GDSC	Tivozanib	2.8506
SIDM00747	LUAD\|lung_NSCLC_adenocarcinoma	p.P91fs*3 (No)	GDSC	Brivanib, BMS-540215	89.6645
SIDM00747	LUAD\|lung_NSCLC_adenocarcinoma	p.P91fs*3 (No)	GDSC	BIBF-1120	10.5909
SIDM00747	LUAD\|lung_NSCLC_adenocarcinoma	p.P91fs*3 (No)	GDSC	Axitinib	37.0818
SIDM00747	LUAD\|lung_NSCLC_adenocarcinoma	p.P91fs*3 (No)	GDSC	Motesanib	38.7849
SIDM00747	LUAD\|lung_NSCLC_adenocarcinoma	p.P91fs*3 (No)	GDSC	Sorafenib	36.405
SIDM00747	LUAD\|lung_NSCLC_adenocarcinoma	p.P91fs*3 (No)	GDSC	Cediranib	171.14
SIDM00747	LUAD\|lung_NSCLC_adenocarcinoma	p.P91fs*3 (No)	GDSC	Foretinib	3.6788
SIDM00719	SCLC\|lung_small_cell_carcinoma	p.E361* (No)	GDSC	Sunitinib	201.0901
SIDM00719	SCLC\|lung_small_cell_carcinoma	p.E361* (No)	GDSC	Sorafenib	67.5275
SIDM00719	SCLC\|lung_small_cell_carcinoma	p.E361* (No)	GDSC	Ponatinib	11.6356
SIDM00719	SCLC\|lung_small_cell_carcinoma	p.E361* (No)	GDSC	Cabozantinib	38.6328
SIDM00719	SCLC\|lung_small_cell_carcinoma	p.E361* (No)	GDSC	Linifanib	24.438
SIDM00719	SCLC\|lung_small_cell_carcinoma	p.E361* (No)	GDSC	Foretinib	24.0044
SIDM00719	SCLC\|lung_small_cell_carcinoma	p.E361* (No)	GDSC	Tivozanib	4.1562
SIDM00719	SCLC\|lung_small_cell_carcinoma	p.E361* (No)	GDSC	Brivanib, BMS-540215	495.8458
SIDM00719	SCLC\|lung_small_cell_carcinoma	p.E361* (No)	GDSC	BIBF-1120	163.7589
SIDM00719	SCLC\|lung_small_cell_carcinoma	p.E361* (No)	GDSC	Axitinib	15.5588
SIDM00719	SCLC\|lung_small_cell_carcinoma	p.E361* (No)	GDSC	Motesanib	67.1185
SIDM00719	SCLC\|lung_small_cell_carcinoma	p.E361* (No)	GDSC	Foretinib	7.2808
SIDM00723	UNCLASSIFIED\|lung_NSCLC_not_specified	p.Q738* (No)	GDSC	Ponatinib	4.7347
SIDM00723	UNCLASSIFIED\|lung_NSCLC_not_specified	p.Q738* (No)	GDSC	Cabozantinib	29.857
SIDM00723	UNCLASSIFIED\|lung_NSCLC_not_specified	p.Q738* (No)	GDSC	Linifanib	18.8773
SIDM00723	UNCLASSIFIED\|lung_NSCLC_not_specified	p.Q738* (No)	GDSC	Foretinib	4.1273
SIDM00723	UNCLASSIFIED\|lung_NSCLC_not_specified	p.Q738* (No)	GDSC	Tivozanib	2.6525
SIDM00723	UNCLASSIFIED\|lung_NSCLC_not_specified	p.Q738* (No)	GDSC	Brivanib, BMS-540215	138.0343
SIDM00723	UNCLASSIFIED\|lung_NSCLC_not_specified	p.Q738* (No)	GDSC	BIBF-1120	16.0042
SIDM00723	UNCLASSIFIED\|lung_NSCLC_not_specified	p.Q738* (No)	GDSC	Axitinib	27.466
SIDM00723	UNCLASSIFIED\|lung_NSCLC_not_specified	p.Q738* (No)	GDSC	Motesanib	19.6715
SIDM01150	LUAD\|lung_NSCLC_adenocarcinoma	p.E730* (No)	GDSC	Ponatinib	1.4735
SIDM01150	LUAD\|lung_NSCLC_adenocarcinoma	p.E730* (No)	GDSC	Cabozantinib	18.5354
SIDM01150	LUAD\|lung_NSCLC_adenocarcinoma	p.E730* (No)	GDSC	Linifanib	13.9573
SIDM01150	LUAD\|lung_NSCLC_adenocarcinoma	p.E730* (No)	GDSC	Foretinib	1.1805
SIDM01150	LUAD\|lung_NSCLC_adenocarcinoma	p.E730* (No)	GDSC	Tivozanib	1.8885
SIDM01150	LUAD\|lung_NSCLC_adenocarcinoma	p.E730* (No)	GDSC	Brivanib, BMS-540215	147.5588
SIDM01150	LUAD\|lung_NSCLC_adenocarcinoma	p.E730* (No)	GDSC	BIBF-1120	210.8736
SIDM01150	LUAD\|lung_NSCLC_adenocarcinoma	p.E730* (No)	GDSC	Axitinib	15.336
SIDM01150	LUAD\|lung_NSCLC_adenocarcinoma	p.E730* (No)	GDSC	Motesanib	15.8628
SIDM00345	UNCLASSIFIED\|lung_NSCLC_large_cell	p.H1004N (No)	GDSC	Ponatinib	0.7662
SIDM00345	UNCLASSIFIED\|lung_NSCLC_large_cell	p.H1004N (No)	GDSC	Cabozantinib	13.3883
SIDM00345	UNCLASSIFIED\|lung_NSCLC_large_cell	p.H1004N (No)	GDSC	Linifanib	15.232
SIDM00345	UNCLASSIFIED\|lung_NSCLC_large_cell	p.H1004N (No)	GDSC	Foretinib	1.169
SIDM00345	UNCLASSIFIED\|lung_NSCLC_large_cell	p.H1004N (No)	GDSC	Tivozanib	0.7104
SIDM00345	UNCLASSIFIED\|lung_NSCLC_large_cell	p.H1004N (No)	GDSC	Brivanib, BMS-540215	97.4062
SIDM00345	UNCLASSIFIED\|lung_NSCLC_large_cell	p.H1004N (No)	GDSC	BIBF-1120	26.2199
SIDM00345	UNCLASSIFIED\|lung_NSCLC_large_cell	p.H1004N (No)	GDSC	Axitinib	14.9862
SIDM00345	UNCLASSIFIED\|lung_NSCLC_large_cell	p.H1004N (No)	GDSC	Motesanib	14.1304
SIDM00345	UNCLASSIFIED\|lung_NSCLC_large_cell	p.H1004N (No)	GDSC	Sorafenib	19.184
SIDM00345	UNCLASSIFIED\|lung_NSCLC_large_cell	p.H1004N (No)	GDSC	Cediranib	9.1918
SIDM00345	UNCLASSIFIED\|lung_NSCLC_large_cell	p.H1004N (No)	GDSC	Foretinib	5.187
SIDM00213	THCA\|thyroid	p.P230L (No)	GDSC	Ponatinib	7.5816
SIDM00213	THCA\|thyroid	p.P230L (No)	GDSC	Cabozantinib	75.1586
SIDM00213	THCA\|thyroid	p.P230L (No)	GDSC	Linifanib	14.9552
SIDM00213	THCA\|thyroid	p.P230L (No)	GDSC	Foretinib	51.0935
SIDM00213	THCA\|thyroid	p.P230L (No)	GDSC	Tivozanib	1.572
SIDM00213	THCA\|thyroid	p.P230L (No)	GDSC	Brivanib, BMS-540215	188.827
SIDM00213	THCA\|thyroid	p.P230L (No)	GDSC	BIBF-1120	296.0943
SIDM00213	THCA\|thyroid	p.P230L (No)	GDSC	Axitinib	19.0517
SIDM00213	THCA\|thyroid	p.P230L (No)	GDSC	Motesanib	8.2212
SIDM00213	THCA\|thyroid	p.P230L (No)	GDSC	Sorafenib	13.542
SIDM00213	THCA\|thyroid	p.P230L (No)	GDSC	Cediranib	9.8013
SIDM00213	THCA\|thyroid	p.P230L (No)	GDSC	Foretinib	4.987
SIDM00189	SKCM\|melanoma	p.E979V (No)	GDSC	Sunitinib	13.01
SIDM00680	COREAD\|large_intestine	p.A10T (No)	GDSC	Ponatinib	2.9188
SIDM00680	COREAD\|large_intestine	p.A10T (No)	GDSC	Cabozantinib	38.5657
SIDM00680	COREAD\|large_intestine	p.A10T (No)	GDSC	Linifanib	24.4282
SIDM00680	COREAD\|large_intestine	p.A10T (No)	GDSC	Foretinib	7.298
SIDM00680	COREAD\|large_intestine	p.A10T (No)	GDSC	Tivozanib	3.3041
SIDM00680	COREAD\|large_intestine	p.A10T (No)	GDSC	Brivanib, BMS-540215	146.1156
SIDM00680	COREAD\|large_intestine	p.A10T (No)	GDSC	BIBF-1120	36.3656
SIDM00680	COREAD\|large_intestine	p.A10T (No)	GDSC	Axitinib	34.4935
SIDM00680	COREAD\|large_intestine	p.A10T (No)	GDSC	Motesanib	28.4604
SIDM00680	COREAD\|large_intestine	p.A10T (No)	GDSC	Sorafenib	29.618
SIDM00680	COREAD\|large_intestine	p.A10T (No)	GDSC	Cediranib	13.981
SIDM00680	COREAD\|large_intestine	p.A10T (No)	GDSC	Foretinib	6.5598
SIDM00749	LUAD\|lung_NSCLC_adenocarcinoma	p.R1126S (No)	GDSC	Ponatinib	8.7734
SIDM00749	LUAD\|lung_NSCLC_adenocarcinoma	p.R1126S (No)	GDSC	Cabozantinib	58.075
SIDM00749	LUAD\|lung_NSCLC_adenocarcinoma	p.R1126S (No)	GDSC	Linifanib	18.1497
SIDM00749	LUAD\|lung_NSCLC_adenocarcinoma	p.R1126S (No)	GDSC	Foretinib	3.4137
SIDM00749	LUAD\|lung_NSCLC_adenocarcinoma	p.R1126S (No)	GDSC	Tivozanib	2.1568
SIDM00749	LUAD\|lung_NSCLC_adenocarcinoma	p.R1126S (No)	GDSC	Brivanib, BMS-540215	182.1331
SIDM00749	LUAD\|lung_NSCLC_adenocarcinoma	p.R1126S (No)	GDSC	BIBF-1120	29.5172
SIDM00749	LUAD\|lung_NSCLC_adenocarcinoma	p.R1126S (No)	GDSC	Axitinib	5.407
SIDM00749	LUAD\|lung_NSCLC_adenocarcinoma	p.R1126S (No)	GDSC	Motesanib	11.8955
SIDM00749	LUAD\|lung_NSCLC_adenocarcinoma	p.R1126S (No)	GDSC	Sorafenib	5.6511
SIDM00749	LUAD\|lung_NSCLC_adenocarcinoma	p.R1126S (No)	GDSC	Cediranib	188.3
SIDM00749	LUAD\|lung_NSCLC_adenocarcinoma	p.R1126S (No)	GDSC	Foretinib	4.4376
SIDM00151	OV\|ovary	p.A853V (No)	GDSC	Axitinib	24.7641
SIDM00151	OV\|ovary	p.A853V (No)	GDSC	Motesanib	51.1276
SIDM00151	OV\|ovary	p.A853V (No)	GDSC	Sorafenib	14.832
SIDM00151	OV\|ovary	p.A853V (No)	GDSC	Cediranib	0.9851
SIDM00151	OV\|ovary	p.A853V (No)	GDSC	Foretinib	0.5798
SIDM00151	OV\|ovary	p.V171L (No)	GDSC	Axitinib	24.7641
SIDM00151	OV\|ovary	p.V171L (No)	GDSC	Motesanib	51.1276
SIDM00151	OV\|ovary	p.V171L (No)	GDSC	Sorafenib	14.832
SIDM00151	OV\|ovary	p.V171L (No)	GDSC	Cediranib	0.9851
SIDM00151	OV\|ovary	p.V171L (No)	GDSC	Foretinib	0.5798
SIDM01139	PAAD\|pancreas	p.V567M (No)	GDSC	Ponatinib	6.7617
SIDM01139	PAAD\|pancreas	p.V567M (No)	GDSC	Cabozantinib	3.7394
SIDM01139	PAAD\|pancreas	p.V567M (No)	GDSC	Linifanib	11.5115
SIDM01139	PAAD\|pancreas	p.V567M (No)	GDSC	Foretinib	0.3556
SIDM01139	PAAD\|pancreas	p.V567M (No)	GDSC	Tivozanib	1.2345
SIDM01139	PAAD\|pancreas	p.V567M (No)	GDSC	Brivanib, BMS-540215	394.7671
SIDM01139	PAAD\|pancreas	p.V567M (No)	GDSC	BIBF-1120	15.639
SIDM01139	PAAD\|pancreas	p.V567M (No)	GDSC	Axitinib	28.5074
SIDM01139	PAAD\|pancreas	p.V567M (No)	GDSC	Motesanib	4.9194
SIDM01139	PAAD\|pancreas	p.V567M (No)	GDSC	Sorafenib	40.342
SIDM01139	PAAD\|pancreas	p.V567M (No)	GDSC	Cediranib	6.2132
SIDM01139	PAAD\|pancreas	p.V567M (No)	GDSC	Foretinib	1.0997
SIDM00683	PRAD\|prostate	p.A1065T (No)	GDSC	Sunitinib	69.7013
SIDM00683	PRAD\|prostate	p.A1065T (No)	GDSC	Sorafenib	18.9467
SIDM00683	PRAD\|prostate	p.A1065T (No)	GDSC	Ponatinib	3.947
SIDM00683	PRAD\|prostate	p.A1065T (No)	GDSC	Cabozantinib	9.9083
SIDM00683	PRAD\|prostate	p.A1065T (No)	GDSC	Linifanib	5.6349
SIDM00683	PRAD\|prostate	p.A1065T (No)	GDSC	Foretinib	5.9943
SIDM00683	PRAD\|prostate	p.A1065T (No)	GDSC	Tivozanib	1.1711
SIDM00683	PRAD\|prostate	p.A1065T (No)	GDSC	Brivanib, BMS-540215	43.4667
SIDM00683	PRAD\|prostate	p.A1065T (No)	GDSC	BIBF-1120	20.0566
SIDM00683	PRAD\|prostate	p.A1065T (No)	GDSC	Axitinib	7.8799
SIDM00683	PRAD\|prostate	p.A1065T (No)	GDSC	Motesanib	30.6555
SIDM00683	PRAD\|prostate	p.A1065T (No)	GDSC	Sorafenib	4.6434
SIDM00683	PRAD\|prostate	p.A1065T (No)	GDSC	Cediranib	8.4465
SIDM00683	PRAD\|prostate	p.A1065T (No)	GDSC	Foretinib	4.473
SIDM00108	SKCM\|melanoma	p.A342V (No)	GDSC	Sunitinib	7.6995
SIDM00108	SKCM\|melanoma	p.A342V (No)	GDSC	Sorafenib	5.6456
SIDM00108	SKCM\|melanoma	p.A342V (No)	GDSC	Ponatinib	6.2969
SIDM00108	SKCM\|melanoma	p.A342V (No)	GDSC	Cabozantinib	12.2021
SIDM00108	SKCM\|melanoma	p.A342V (No)	GDSC	Linifanib	17.4797
SIDM00108	SKCM\|melanoma	p.A342V (No)	GDSC	Foretinib	1.7957
SIDM00108	SKCM\|melanoma	p.A342V (No)	GDSC	Tivozanib	1.4097
SIDM00108	SKCM\|melanoma	p.A342V (No)	GDSC	Brivanib, BMS-540215	360.8232
SIDM00108	SKCM\|melanoma	p.A342V (No)	GDSC	BIBF-1120	23.6128
SIDM00108	SKCM\|melanoma	p.A342V (No)	GDSC	Axitinib	31.6666
SIDM00108	SKCM\|melanoma	p.A342V (No)	GDSC	Motesanib	17.3508
SIDM00108	SKCM\|melanoma	p.A342V (No)	GDSC	Sorafenib	19.257
SIDM00108	SKCM\|melanoma	p.A342V (No)	GDSC	Cediranib	12.764
SIDM00108	SKCM\|melanoma	p.A342V (No)	GDSC	Foretinib	4.0544
SIDM00527	COREAD\|large_intestine	p.R1032Q (No)	GDSC	Sunitinib	59.3868
SIDM00527	COREAD\|large_intestine	p.R1032Q (No)	GDSC	Sorafenib	31.899
SIDM00527	COREAD\|large_intestine	p.R1032Q (No)	GDSC	Ponatinib	6.4962
SIDM00527	COREAD\|large_intestine	p.R1032Q (No)	GDSC	Cabozantinib	18.2032
SIDM00527	COREAD\|large_intestine	p.R1032Q (No)	GDSC	Linifanib	11.9348
SIDM00527	COREAD\|large_intestine	p.R1032Q (No)	GDSC	Foretinib	0.9942
SIDM00527	COREAD\|large_intestine	p.R1032Q (No)	GDSC	Tivozanib	1.473
SIDM00527	COREAD\|large_intestine	p.R1032Q (No)	GDSC	Brivanib, BMS-540215	156.2331
SIDM00527	COREAD\|large_intestine	p.R1032Q (No)	GDSC	BIBF-1120	178.271
SIDM00527	COREAD\|large_intestine	p.R1032Q (No)	GDSC	Axitinib	4.7294
SIDM00527	COREAD\|large_intestine	p.R1032Q (No)	GDSC	Motesanib	5.9664
SIDM00527	COREAD\|large_intestine	p.R1032Q (No)	GDSC	Sorafenib	8.3177
SIDM00527	COREAD\|large_intestine	p.R1032Q (No)	GDSC	Cediranib	6.1462
SIDM01007	ALL\|lymphoblastic_leukemia	p.R962H (No)	GDSC	Sunitinib	2.0565
SIDM01007	ALL\|lymphoblastic_leukemia	p.R962H (No)	GDSC	Sorafenib	4.9994
SIDM01007	ALL\|lymphoblastic_leukemia	p.R962H (No)	GDSC	Ponatinib	0.2735
SIDM01007	ALL\|lymphoblastic_leukemia	p.R962H (No)	GDSC	Cabozantinib	1.7755
SIDM01007	ALL\|lymphoblastic_leukemia	p.R962H (No)	GDSC	Linifanib	4.2428
SIDM01007	ALL\|lymphoblastic_leukemia	p.R962H (No)	GDSC	Foretinib	0.1908
SIDM01007	ALL\|lymphoblastic_leukemia	p.R962H (No)	GDSC	Tivozanib	0.7699
SIDM01007	ALL\|lymphoblastic_leukemia	p.R962H (No)	GDSC	Brivanib, BMS-540215	38.3399
SIDM01007	ALL\|lymphoblastic_leukemia	p.R962H (No)	GDSC	BIBF-1120	1.9963
SIDM01007	ALL\|lymphoblastic_leukemia	p.R962H (No)	GDSC	Axitinib	2.2297
SIDM01007	ALL\|lymphoblastic_leukemia	p.R962H (No)	GDSC	Motesanib	12.841
SIDM01007	ALL\|lymphoblastic_leukemia	p.R962H (No)	GDSC	Sorafenib	3.5437
SIDM01007	ALL\|lymphoblastic_leukemia	p.R962H (No)	GDSC	Cediranib	3.4309
SIDM01007	ALL\|lymphoblastic_leukemia	p.R962H (No)	GDSC	Foretinib	0.4275
SIDM01174	CESC\|cervix	p.G220V (No)	GDSC	Ponatinib	10.0266
SIDM01174	CESC\|cervix	p.G220V (No)	GDSC	Cabozantinib	78.0231
SIDM01174	CESC\|cervix	p.G220V (No)	GDSC	Linifanib	15.9509
SIDM01174	CESC\|cervix	p.G220V (No)	GDSC	Foretinib	32.5213
SIDM01174	CESC\|cervix	p.G220V (No)	GDSC	Tivozanib	2.4587
SIDM01174	CESC\|cervix	p.G220V (No)	GDSC	Brivanib, BMS-540215	413.8767
SIDM01174	CESC\|cervix	p.G220V (No)	GDSC	BIBF-1120	220.9022
SIDM01174	CESC\|cervix	p.G220V (No)	GDSC	Motesanib	3.1517
SIDM01174	CESC\|cervix	p.G220V (No)	GDSC	Sorafenib	28.131
SIDM01174	CESC\|cervix	p.G220V (No)	GDSC	Cediranib	42.462
SIDM01174	CESC\|cervix	p.G220V (No)	GDSC	Foretinib	203.12
SIDM01190	BLCA\|bladder	p.G1261D (No)	GDSC	Ponatinib	1.3172
SIDM01190	BLCA\|bladder	p.G1261D (No)	GDSC	Cabozantinib	28.4658
SIDM01190	BLCA\|bladder	p.G1261D (No)	GDSC	Linifanib	18.5661
SIDM01190	BLCA\|bladder	p.G1261D (No)	GDSC	Foretinib	1.3236
SIDM01190	BLCA\|bladder	p.G1261D (No)	GDSC	Tivozanib	2.1029
SIDM01190	BLCA\|bladder	p.G1261D (No)	GDSC	Brivanib, BMS-540215	68.7445
SIDM01190	BLCA\|bladder	p.G1261D (No)	GDSC	BIBF-1120	56.4349
SIDM01190	BLCA\|bladder	p.G1261D (No)	GDSC	Axitinib	14.4478
SIDM01190	BLCA\|bladder	p.G1261D (No)	GDSC	Motesanib	13.9474
SIDM01190	BLCA\|bladder	p.G1261D (No)	GDSC	Sorafenib	47.023
SIDM01190	BLCA\|bladder	p.G1261D (No)	GDSC	Cediranib	8.1532
SIDM01190	BLCA\|bladder	p.G1261D (No)	GDSC	Foretinib	3.385
SIDM00052	ESCA\|oesophagus	p.I1330L (No)	GDSC	Sunitinib	4.4854
SIDM00052	ESCA\|oesophagus	p.I1330L (No)	GDSC	Ponatinib	0.8399
SIDM00052	ESCA\|oesophagus	p.I1330L (No)	GDSC	Cabozantinib	50.8389
SIDM00052	ESCA\|oesophagus	p.I1330L (No)	GDSC	Linifanib	9.4311
SIDM00052	ESCA\|oesophagus	p.I1330L (No)	GDSC	Foretinib	18.4258
SIDM00052	ESCA\|oesophagus	p.I1330L (No)	GDSC	Tivozanib	1.6191
SIDM00052	ESCA\|oesophagus	p.I1330L (No)	GDSC	Brivanib, BMS-540215	40.8773
SIDM00052	ESCA\|oesophagus	p.I1330L (No)	GDSC	BIBF-1120	9.6454
SIDM00052	ESCA\|oesophagus	p.I1330L (No)	GDSC	Axitinib	12.7993
SIDM00052	ESCA\|oesophagus	p.I1330L (No)	GDSC	Motesanib	17.5966
SIDM00214	COREAD\|large_intestine	p.R1118Q (No)	GDSC	Cabozantinib	16.8316
SIDM00214	COREAD\|large_intestine	p.R1118Q (No)	GDSC	Linifanib	18.5488
SIDM00214	COREAD\|large_intestine	p.R1118Q (No)	GDSC	Foretinib	0.6811
SIDM00214	COREAD\|large_intestine	p.R1118Q (No)	GDSC	Tivozanib	1.7027
SIDM00214	COREAD\|large_intestine	p.R1118Q (No)	GDSC	Brivanib, BMS-540215	122.9524
SIDM00214	COREAD\|large_intestine	p.R1118Q (No)	GDSC	BIBF-1120	42.7564
SIDM00214	COREAD\|large_intestine	p.R1118Q (No)	GDSC	Axitinib	13.533
SIDM00214	COREAD\|large_intestine	p.R1118Q (No)	GDSC	Motesanib	41.1438
SIDM00214	COREAD\|large_intestine	p.R1118Q (No)	GDSC	Sorafenib	7.7438
SIDM00214	COREAD\|large_intestine	p.R1118Q (No)	GDSC	Cediranib	9.7097
SIDM00214	COREAD\|large_intestine	p.R1066C (No)	GDSC	Cabozantinib	16.8316
SIDM00214	COREAD\|large_intestine	p.R1066C (No)	GDSC	Linifanib	18.5488
SIDM00214	COREAD\|large_intestine	p.R1066C (No)	GDSC	Foretinib	0.6811
SIDM00214	COREAD\|large_intestine	p.R1066C (No)	GDSC	Tivozanib	1.7027
SIDM00214	COREAD\|large_intestine	p.R1066C (No)	GDSC	Brivanib, BMS-540215	122.9524
SIDM00214	COREAD\|large_intestine	p.R1066C (No)	GDSC	BIBF-1120	42.7564
SIDM00214	COREAD\|large_intestine	p.R1066C (No)	GDSC	Axitinib	13.533
SIDM00214	COREAD\|large_intestine	p.R1066C (No)	GDSC	Motesanib	41.1438
SIDM00214	COREAD\|large_intestine	p.R1066C (No)	GDSC	Sorafenib	7.7438
SIDM00214	COREAD\|large_intestine	p.R1066C (No)	GDSC	Cediranib	9.7097
SIDM00214	COREAD\|large_intestine	p.A532V (No)	GDSC	Cabozantinib	16.8316
SIDM00214	COREAD\|large_intestine	p.A532V (No)	GDSC	Linifanib	18.5488
SIDM00214	COREAD\|large_intestine	p.A532V (No)	GDSC	Foretinib	0.6811
SIDM00214	COREAD\|large_intestine	p.A532V (No)	GDSC	Tivozanib	1.7027
SIDM00214	COREAD\|large_intestine	p.A532V (No)	GDSC	Brivanib, BMS-540215	122.9524
SIDM00214	COREAD\|large_intestine	p.A532V (No)	GDSC	BIBF-1120	42.7564
SIDM00214	COREAD\|large_intestine	p.A532V (No)	GDSC	Axitinib	13.533
SIDM00214	COREAD\|large_intestine	p.A532V (No)	GDSC	Motesanib	41.1438
SIDM00214	COREAD\|large_intestine	p.A532V (No)	GDSC	Sorafenib	7.7438
SIDM00214	COREAD\|large_intestine	p.A532V (No)	GDSC	Cediranib	9.7097
SIDM01088	UNCLASSIFIED\|endometrium	p.D710A (No)	GDSC	Sunitinib	2.3039
SIDM01088	UNCLASSIFIED\|endometrium	p.D710A (No)	GDSC	Sorafenib	7.3363
SIDM01088	UNCLASSIFIED\|endometrium	p.D710A (No)	GDSC	Ponatinib	1.0148
SIDM01088	UNCLASSIFIED\|endometrium	p.D710A (No)	GDSC	Cabozantinib	5.1141
SIDM01088	UNCLASSIFIED\|endometrium	p.D710A (No)	GDSC	Linifanib	11.8922
SIDM01088	UNCLASSIFIED\|endometrium	p.D710A (No)	GDSC	Foretinib	0.3304
SIDM01088	UNCLASSIFIED\|endometrium	p.D710A (No)	GDSC	Tivozanib	1.6115
SIDM01088	UNCLASSIFIED\|endometrium	p.D710A (No)	GDSC	Brivanib, BMS-540215	279.0425
SIDM01088	UNCLASSIFIED\|endometrium	p.D710A (No)	GDSC	BIBF-1120	2.6344
SIDM01088	UNCLASSIFIED\|endometrium	p.D710A (No)	GDSC	Axitinib	4.2957
SIDM01088	UNCLASSIFIED\|endometrium	p.D710A (No)	GDSC	Motesanib	25.2017
SIDM01088	UNCLASSIFIED\|endometrium	p.D710A (No)	GDSC	Sorafenib	7.5102
SIDM01088	UNCLASSIFIED\|endometrium	p.D710A (No)	GDSC	Cediranib	8.3902
SIDM01088	UNCLASSIFIED\|endometrium	p.D710A (No)	GDSC	Foretinib	1.992
SIDM00188	KIRC\|kidney	p.A248G (No)	GDSC	Sunitinib	5.2071
SIDM00188	KIRC\|kidney	p.A248G (No)	GDSC	Sorafenib	57.2003
SIDM00188	KIRC\|kidney	p.A248G (No)	GDSC	Ponatinib	8.8614
SIDM00188	KIRC\|kidney	p.A248G (No)	GDSC	Cabozantinib	8.4821
SIDM00188	KIRC\|kidney	p.A248G (No)	GDSC	Linifanib	12.7898
SIDM00188	KIRC\|kidney	p.A248G (No)	GDSC	Foretinib	0.5757
SIDM00188	KIRC\|kidney	p.A248G (No)	GDSC	Tivozanib	2.2082
SIDM00188	KIRC\|kidney	p.A248G (No)	GDSC	Brivanib, BMS-540215	22.2403
SIDM00188	KIRC\|kidney	p.A248G (No)	GDSC	BIBF-1120	3.8194
SIDM00188	KIRC\|kidney	p.A248G (No)	GDSC	Axitinib	9.4445
SIDM00188	KIRC\|kidney	p.A248G (No)	GDSC	Motesanib	10.4975
SIDM00292	SCLC\|lung_small_cell_carcinoma	p.L1156F (No)	GDSC	Sunitinib	159.8703
SIDM00292	SCLC\|lung_small_cell_carcinoma	p.L1156F (No)	GDSC	Sorafenib	19.7335
SIDM00292	SCLC\|lung_small_cell_carcinoma	p.L1156F (No)	GDSC	Ponatinib	6.0105
SIDM00292	SCLC\|lung_small_cell_carcinoma	p.L1156F (No)	GDSC	Cabozantinib	46.6586
SIDM00292	SCLC\|lung_small_cell_carcinoma	p.L1156F (No)	GDSC	Linifanib	28.1567
SIDM00292	SCLC\|lung_small_cell_carcinoma	p.L1156F (No)	GDSC	Foretinib	1.9059
SIDM00292	SCLC\|lung_small_cell_carcinoma	p.L1156F (No)	GDSC	Tivozanib	0.8688
SIDM00292	SCLC\|lung_small_cell_carcinoma	p.L1156F (No)	GDSC	Brivanib, BMS-540215	221.9895
SIDM00292	SCLC\|lung_small_cell_carcinoma	p.L1156F (No)	GDSC	BIBF-1120	22.4691
SIDM00292	SCLC\|lung_small_cell_carcinoma	p.L1156F (No)	GDSC	Axitinib	43.702
SIDM00292	SCLC\|lung_small_cell_carcinoma	p.L1156F (No)	GDSC	Motesanib	39.1268
SIDM00292	SCLC\|lung_small_cell_carcinoma	p.L1156F (No)	GDSC	Sorafenib	22.728
SIDM00292	SCLC\|lung_small_cell_carcinoma	p.L1156F (No)	GDSC	Cediranib	12.633
SIDM00292	SCLC\|lung_small_cell_carcinoma	p.L1156F (No)	GDSC	Foretinib	12.426
SIDM00482	LCML\|chronic_myeloid_leukaemia	p.K1270Q (No)	GDSC	Sunitinib	15.1007
SIDM00482	LCML\|chronic_myeloid_leukaemia	p.K1270Q (No)	GDSC	Sorafenib	7.8445
SIDM00482	LCML\|chronic_myeloid_leukaemia	p.K1270Q (No)	GDSC	Ponatinib	4.7966
SIDM00482	LCML\|chronic_myeloid_leukaemia	p.K1270Q (No)	GDSC	Cabozantinib	8.4184
SIDM00482	LCML\|chronic_myeloid_leukaemia	p.K1270Q (No)	GDSC	Linifanib	9.7802
SIDM00482	LCML\|chronic_myeloid_leukaemia	p.K1270Q (No)	GDSC	Foretinib	1.1718
SIDM00482	LCML\|chronic_myeloid_leukaemia	p.K1270Q (No)	GDSC	Tivozanib	1.0895
SIDM00482	LCML\|chronic_myeloid_leukaemia	p.K1270Q (No)	GDSC	Brivanib, BMS-540215	8.019
SIDM00482	LCML\|chronic_myeloid_leukaemia	p.K1270Q (No)	GDSC	BIBF-1120	6.7195
SIDM00482	LCML\|chronic_myeloid_leukaemia	p.K1270Q (No)	GDSC	Axitinib	2.999
SIDM00482	LCML\|chronic_myeloid_leukaemia	p.K1270Q (No)	GDSC	Motesanib	24.3704
SIDM00482	LCML\|chronic_myeloid_leukaemia	p.K1270Q (No)	GDSC	Foretinib	1.7865
SIDM01039	UNCLASSIFIED\|urogenital_system_other	p.G424A (No)	GDSC	Sunitinib	2.8272
SIDM01039	UNCLASSIFIED\|urogenital_system_other	p.G424A (No)	GDSC	Sorafenib	6.9852
SIDM01039	UNCLASSIFIED\|urogenital_system_other	p.G424A (No)	GDSC	Ponatinib	5.7115
SIDM01039	UNCLASSIFIED\|urogenital_system_other	p.G424A (No)	GDSC	Cabozantinib	42.8823
SIDM01039	UNCLASSIFIED\|urogenital_system_other	p.G424A (No)	GDSC	Linifanib	11.4189
SIDM01039	UNCLASSIFIED\|urogenital_system_other	p.G424A (No)	GDSC	Foretinib	3.0561
SIDM01039	UNCLASSIFIED\|urogenital_system_other	p.G424A (No)	GDSC	Tivozanib	1.3034
SIDM01039	UNCLASSIFIED\|urogenital_system_other	p.G424A (No)	GDSC	Brivanib, BMS-540215	52.7285
SIDM01039	UNCLASSIFIED\|urogenital_system_other	p.G424A (No)	GDSC	BIBF-1120	38.929
SIDM01039	UNCLASSIFIED\|urogenital_system_other	p.G424A (No)	GDSC	Axitinib	9.7418
SIDM01039	UNCLASSIFIED\|urogenital_system_other	p.G424A (No)	GDSC	Motesanib	18.8844
SIDM00388	UNCLASSIFIED\|B_cell_leukemia	p.G99E (No)	GDSC	Sunitinib	5.8574
SIDM00388	UNCLASSIFIED\|B_cell_leukemia	p.G99E (No)	GDSC	Sorafenib	3.2571
SIDM00388	UNCLASSIFIED\|B_cell_leukemia	p.G99E (No)	GDSC	Ponatinib	0.6349
SIDM00388	UNCLASSIFIED\|B_cell_leukemia	p.G99E (No)	GDSC	Cabozantinib	4.4868
SIDM00388	UNCLASSIFIED\|B_cell_leukemia	p.G99E (No)	GDSC	Linifanib	8.7913
SIDM00388	UNCLASSIFIED\|B_cell_leukemia	p.G99E (No)	GDSC	Foretinib	0.3712
SIDM00388	UNCLASSIFIED\|B_cell_leukemia	p.G99E (No)	GDSC	Tivozanib	1.0062
SIDM00388	UNCLASSIFIED\|B_cell_leukemia	p.G99E (No)	GDSC	Brivanib, BMS-540215	63.0613
SIDM00388	UNCLASSIFIED\|B_cell_leukemia	p.G99E (No)	GDSC	BIBF-1120	22.0568
SIDM00388	UNCLASSIFIED\|B_cell_leukemia	p.G99E (No)	GDSC	Axitinib	5.4185
SIDM00388	UNCLASSIFIED\|B_cell_leukemia	p.G99E (No)	GDSC	Motesanib	21.9259
SIDM00388	UNCLASSIFIED\|B_cell_leukemia	p.G99E (No)	GDSC	Sorafenib	5.6057
SIDM00388	UNCLASSIFIED\|B_cell_leukemia	p.G99E (No)	GDSC	Cediranib	6.792
SIDM00388	UNCLASSIFIED\|B_cell_leukemia	p.G99E (No)	GDSC	Foretinib	4.5486
SIDM00792	SCLC\|lung_small_cell_carcinoma	p.G539R (No)	GDSC	Ponatinib	1.7228
SIDM00792	SCLC\|lung_small_cell_carcinoma	p.G539R (No)	GDSC	Cabozantinib	7.7925
SIDM00792	SCLC\|lung_small_cell_carcinoma	p.G539R (No)	GDSC	Linifanib	7.4125
SIDM00792	SCLC\|lung_small_cell_carcinoma	p.G539R (No)	GDSC	Foretinib	0.6555
SIDM00792	SCLC\|lung_small_cell_carcinoma	p.G539R (No)	GDSC	Tivozanib	1.2145
SIDM00792	SCLC\|lung_small_cell_carcinoma	p.G539R (No)	GDSC	Brivanib, BMS-540215	39.1671
SIDM00792	SCLC\|lung_small_cell_carcinoma	p.G539R (No)	GDSC	BIBF-1120	1.9696
SIDM00792	SCLC\|lung_small_cell_carcinoma	p.G539R (No)	GDSC	Axitinib	11.1658
SIDM00792	SCLC\|lung_small_cell_carcinoma	p.G539R (No)	GDSC	Motesanib	3.2422
SIDM00792	SCLC\|lung_small_cell_carcinoma	p.G539R (No)	GDSC	Sorafenib	8.8626
SIDM00792	SCLC\|lung_small_cell_carcinoma	p.G539R (No)	GDSC	Cediranib	10.243
SIDM00792	SCLC\|lung_small_cell_carcinoma	p.G539R (No)	GDSC	Foretinib	3.7573
SIDM00792	SCLC\|lung_small_cell_carcinoma	p.D58G (No)	GDSC	Ponatinib	1.7228
SIDM00792	SCLC\|lung_small_cell_carcinoma	p.D58G (No)	GDSC	Cabozantinib	7.7925
SIDM00792	SCLC\|lung_small_cell_carcinoma	p.D58G (No)	GDSC	Linifanib	7.4125
SIDM00792	SCLC\|lung_small_cell_carcinoma	p.D58G (No)	GDSC	Foretinib	0.6555
SIDM00792	SCLC\|lung_small_cell_carcinoma	p.D58G (No)	GDSC	Tivozanib	1.2145
SIDM00792	SCLC\|lung_small_cell_carcinoma	p.D58G (No)	GDSC	Brivanib, BMS-540215	39.1671
SIDM00792	SCLC\|lung_small_cell_carcinoma	p.D58G (No)	GDSC	BIBF-1120	1.9696
SIDM00792	SCLC\|lung_small_cell_carcinoma	p.D58G (No)	GDSC	Axitinib	11.1658
SIDM00792	SCLC\|lung_small_cell_carcinoma	p.D58G (No)	GDSC	Motesanib	3.2422
SIDM00792	SCLC\|lung_small_cell_carcinoma	p.D58G (No)	GDSC	Sorafenib	8.8626
SIDM00792	SCLC\|lung_small_cell_carcinoma	p.D58G (No)	GDSC	Cediranib	10.243
SIDM00792	SCLC\|lung_small_cell_carcinoma	p.D58G (No)	GDSC	Foretinib	3.7573
SIDM00792	SCLC\|lung_small_cell_carcinoma	p.D58Y (No)	GDSC	Ponatinib	1.7228
SIDM00792	SCLC\|lung_small_cell_carcinoma	p.D58Y (No)	GDSC	Cabozantinib	7.7925
SIDM00792	SCLC\|lung_small_cell_carcinoma	p.D58Y (No)	GDSC	Linifanib	7.4125
SIDM00792	SCLC\|lung_small_cell_carcinoma	p.D58Y (No)	GDSC	Foretinib	0.6555
SIDM00792	SCLC\|lung_small_cell_carcinoma	p.D58Y (No)	GDSC	Tivozanib	1.2145
SIDM00792	SCLC\|lung_small_cell_carcinoma	p.D58Y (No)	GDSC	Brivanib, BMS-540215	39.1671
SIDM00792	SCLC\|lung_small_cell_carcinoma	p.D58Y (No)	GDSC	BIBF-1120	1.9696
SIDM00792	SCLC\|lung_small_cell_carcinoma	p.D58Y (No)	GDSC	Axitinib	11.1658
SIDM00792	SCLC\|lung_small_cell_carcinoma	p.D58Y (No)	GDSC	Motesanib	3.2422
SIDM00792	SCLC\|lung_small_cell_carcinoma	p.D58Y (No)	GDSC	Sorafenib	8.8626
SIDM00792	SCLC\|lung_small_cell_carcinoma	p.D58Y (No)	GDSC	Cediranib	10.243
SIDM00792	SCLC\|lung_small_cell_carcinoma	p.D58Y (No)	GDSC	Foretinib	3.7573
SIDM00853	UNCLASSIFIED\|soft_tissue_other	p.P230S (No)	GDSC	Ponatinib	0.8922
SIDM00853	UNCLASSIFIED\|soft_tissue_other	p.P230S (No)	GDSC	Cabozantinib	52.6341
SIDM00853	UNCLASSIFIED\|soft_tissue_other	p.P230S (No)	GDSC	Linifanib	12.797
SIDM00853	UNCLASSIFIED\|soft_tissue_other	p.P230S (No)	GDSC	Foretinib	7.9117
SIDM00853	UNCLASSIFIED\|soft_tissue_other	p.P230S (No)	GDSC	Tivozanib	1.735
SIDM00853	UNCLASSIFIED\|soft_tissue_other	p.P230S (No)	GDSC	Brivanib, BMS-540215	49.6068
SIDM00853	UNCLASSIFIED\|soft_tissue_other	p.P230S (No)	GDSC	BIBF-1120	9.7502
SIDM00853	UNCLASSIFIED\|soft_tissue_other	p.P230S (No)	GDSC	Axitinib	16.5624
SIDM00853	UNCLASSIFIED\|soft_tissue_other	p.P230S (No)	GDSC	Sorafenib	10.585
SIDM00853	UNCLASSIFIED\|soft_tissue_other	p.P230S (No)	GDSC	Cediranib	8.9193
SIDM00853	UNCLASSIFIED\|soft_tissue_other	p.P230S (No)	GDSC	Foretinib	2.6561
SIDM00333	UCEC\|endometrium	p.A750T (No)	GDSC	Ponatinib	1.1816
SIDM00333	UCEC\|endometrium	p.A750T (No)	GDSC	Cabozantinib	42.0625
SIDM00333	UCEC\|endometrium	p.A750T (No)	GDSC	Linifanib	10.7273
SIDM00333	UCEC\|endometrium	p.A750T (No)	GDSC	Foretinib	2.8306
SIDM00333	UCEC\|endometrium	p.A750T (No)	GDSC	Tivozanib	1.4343
SIDM00333	UCEC\|endometrium	p.A750T (No)	GDSC	Brivanib, BMS-540215	68.9695
SIDM00333	UCEC\|endometrium	p.A750T (No)	GDSC	BIBF-1120	15.4151
SIDM00333	UCEC\|endometrium	p.A750T (No)	GDSC	Axitinib	17.1661
SIDM00333	UCEC\|endometrium	p.A750T (No)	GDSC	Motesanib	2.8772
SIDM00333	UCEC\|endometrium	p.A750T (No)	GDSC	Sorafenib	8.8517
SIDM00333	UCEC\|endometrium	p.A750T (No)	GDSC	Cediranib	5.4692
SIDM00333	UCEC\|endometrium	p.A750T (No)	GDSC	Foretinib	7.9407
SIDM00523	SCLC\|lung_small_cell_carcinoma	p.D558A (No)	GDSC	Ponatinib	3.9322
SIDM00523	SCLC\|lung_small_cell_carcinoma	p.D558A (No)	GDSC	Cabozantinib	100.7682
SIDM00523	SCLC\|lung_small_cell_carcinoma	p.D558A (No)	GDSC	Linifanib	12.8922
SIDM00523	SCLC\|lung_small_cell_carcinoma	p.D558A (No)	GDSC	Foretinib	23.5981
SIDM00523	SCLC\|lung_small_cell_carcinoma	p.D558A (No)	GDSC	Tivozanib	2.5251
SIDM00523	SCLC\|lung_small_cell_carcinoma	p.D558A (No)	GDSC	Brivanib, BMS-540215	58.8655
SIDM00523	SCLC\|lung_small_cell_carcinoma	p.D558A (No)	GDSC	BIBF-1120	21.643
SIDM00523	SCLC\|lung_small_cell_carcinoma	p.D558A (No)	GDSC	Axitinib	33.6251
SIDM00523	SCLC\|lung_small_cell_carcinoma	p.D558A (No)	GDSC	Motesanib	15.0905
SIDM00523	SCLC\|lung_small_cell_carcinoma	p.D558A (No)	GDSC	Sorafenib	4.9166
SIDM00523	SCLC\|lung_small_cell_carcinoma	p.D558A (No)	GDSC	Cediranib	14.216
SIDM00523	SCLC\|lung_small_cell_carcinoma	p.D558A (No)	GDSC	Foretinib	2.6383
SIDM00999	BLCA\|bladder	p.D958Y (No)	GDSC	Ponatinib	1.1381
SIDM00999	BLCA\|bladder	p.D958Y (No)	GDSC	Cabozantinib	36.0491
SIDM00999	BLCA\|bladder	p.D958Y (No)	GDSC	Linifanib	5.7148
SIDM00999	BLCA\|bladder	p.D958Y (No)	GDSC	Foretinib	1.187
SIDM00999	BLCA\|bladder	p.D958Y (No)	GDSC	Tivozanib	0.9461
SIDM00999	BLCA\|bladder	p.D958Y (No)	GDSC	Brivanib, BMS-540215	17.4625
SIDM00999	BLCA\|bladder	p.D958Y (No)	GDSC	BIBF-1120	10.8939
SIDM00999	BLCA\|bladder	p.D958Y (No)	GDSC	Axitinib	2.4148
SIDM00999	BLCA\|bladder	p.D958Y (No)	GDSC	Motesanib	4.9658
SIDM00999	BLCA\|bladder	p.D958Y (No)	GDSC	Sorafenib	8.0689
SIDM00999	BLCA\|bladder	p.D958Y (No)	GDSC	Cediranib	5.4135
SIDM00999	BLCA\|bladder	p.D958Y (No)	GDSC	Foretinib	1.4814
SIDM01101	NB\|neuroblastoma	p.L31P (No)	GDSC	Ponatinib	9.6931
SIDM01101	NB\|neuroblastoma	p.L31P (No)	GDSC	Cabozantinib	75.7912
SIDM01101	NB\|neuroblastoma	p.L31P (No)	GDSC	Linifanib	16.2906
SIDM01101	NB\|neuroblastoma	p.L31P (No)	GDSC	Foretinib	1.0591
SIDM01101	NB\|neuroblastoma	p.L31P (No)	GDSC	Tivozanib	2.2676
SIDM01101	NB\|neuroblastoma	p.L31P (No)	GDSC	Brivanib, BMS-540215	336.4549
SIDM01101	NB\|neuroblastoma	p.L31P (No)	GDSC	BIBF-1120	408.6594
SIDM01101	NB\|neuroblastoma	p.L31P (No)	GDSC	Axitinib	14.8997
SIDM01101	NB\|neuroblastoma	p.L31P (No)	GDSC	Motesanib	17.507
SIDM01101	NB\|neuroblastoma	p.L31P (No)	GDSC	Sorafenib	23.461
SIDM01101	NB\|neuroblastoma	p.L31P (No)	GDSC	Cediranib	19.488
SIDM01101	NB\|neuroblastoma	p.L31P (No)	GDSC	Foretinib	3.9339
SIDM00217	COREAD\|large_intestine	p.A1030V (No)	GDSC	Cabozantinib	12.0756
SIDM00217	COREAD\|large_intestine	p.A1030V (No)	GDSC	Linifanib	18.1376
SIDM00217	COREAD\|large_intestine	p.A1030V (No)	GDSC	Foretinib	1.6723
SIDM00217	COREAD\|large_intestine	p.A1030V (No)	GDSC	Tivozanib	2.681
SIDM00217	COREAD\|large_intestine	p.A1030V (No)	GDSC	Brivanib, BMS-540215	386.8326
SIDM00217	COREAD\|large_intestine	p.A1030V (No)	GDSC	BIBF-1120	16.5032
SIDM00217	COREAD\|large_intestine	p.A772V (No)	GDSC	Cabozantinib	12.0756
SIDM00217	COREAD\|large_intestine	p.A772V (No)	GDSC	Linifanib	18.1376
SIDM00217	COREAD\|large_intestine	p.A772V (No)	GDSC	Foretinib	1.6723
SIDM00217	COREAD\|large_intestine	p.A772V (No)	GDSC	Tivozanib	2.681
SIDM00217	COREAD\|large_intestine	p.A772V (No)	GDSC	Brivanib, BMS-540215	386.8326
SIDM00217	COREAD\|large_intestine	p.A772V (No)	GDSC	BIBF-1120	16.5032
SIDM00217	COREAD\|large_intestine	p.R725H (No)	GDSC	Cabozantinib	12.0756
SIDM00217	COREAD\|large_intestine	p.R725H (No)	GDSC	Linifanib	18.1376
SIDM00217	COREAD\|large_intestine	p.R725H (No)	GDSC	Foretinib	1.6723
SIDM00217	COREAD\|large_intestine	p.R725H (No)	GDSC	Tivozanib	2.681
SIDM00217	COREAD\|large_intestine	p.R725H (No)	GDSC	Brivanib, BMS-540215	386.8326
SIDM00217	COREAD\|large_intestine	p.R725H (No)	GDSC	BIBF-1120	16.5032
SIDM00217	COREAD\|large_intestine	p.A45D (No)	GDSC	Cabozantinib	12.0756
SIDM00217	COREAD\|large_intestine	p.A45D (No)	GDSC	Linifanib	18.1376
SIDM00217	COREAD\|large_intestine	p.A45D (No)	GDSC	Foretinib	1.6723
SIDM00217	COREAD\|large_intestine	p.A45D (No)	GDSC	Tivozanib	2.681
SIDM00217	COREAD\|large_intestine	p.A45D (No)	GDSC	Brivanib, BMS-540215	386.8326
SIDM00217	COREAD\|large_intestine	p.A45D (No)	GDSC	BIBF-1120	16.5032
SIDM00140	SKCM\|melanoma	p.S1037L (No)	GDSC	Ponatinib	5.6195
SIDM00140	SKCM\|melanoma	p.S1037L (No)	GDSC	Linifanib	13.1936
SIDM00140	SKCM\|melanoma	p.S1037L (No)	GDSC	Tivozanib	1.2935
SIDM00140	SKCM\|melanoma	p.S1037L (No)	GDSC	Brivanib, BMS-540215	121.0887
SIDM00140	SKCM\|melanoma	p.S1037L (No)	GDSC	BIBF-1120	5.8392
SIDM00140	SKCM\|melanoma	p.S1037L (No)	GDSC	Axitinib	22.5146
SIDM00140	SKCM\|melanoma	p.S1037L (No)	GDSC	Motesanib	4.4263
SIDM00140	SKCM\|melanoma	p.S1037L (No)	GDSC	Sorafenib	6.2025
SIDM00140	SKCM\|melanoma	p.S1037L (No)	GDSC	Cediranib	5.3822
SIDM00140	SKCM\|melanoma	p.S1037L (No)	GDSC	Foretinib	0.5815
SIDM00948	UNCLASSIFIED\|Burkitt_lymphoma	p.E979G (No)	GDSC	Sunitinib	7.4015
SIDM00948	UNCLASSIFIED\|Burkitt_lymphoma	p.E979G (No)	GDSC	Sorafenib	34.6648
SIDM00948	UNCLASSIFIED\|Burkitt_lymphoma	p.E979G (No)	GDSC	Ponatinib	7.2309
SIDM00948	UNCLASSIFIED\|Burkitt_lymphoma	p.E979G (No)	GDSC	Cabozantinib	72.271
SIDM00948	UNCLASSIFIED\|Burkitt_lymphoma	p.E979G (No)	GDSC	Linifanib	14.4617
SIDM00948	UNCLASSIFIED\|Burkitt_lymphoma	p.E979G (No)	GDSC	Foretinib	1.9945
SIDM00948	UNCLASSIFIED\|Burkitt_lymphoma	p.E979G (No)	GDSC	Tivozanib	1.7457
SIDM00948	UNCLASSIFIED\|Burkitt_lymphoma	p.E979G (No)	GDSC	Brivanib, BMS-540215	81.8243
SIDM00948	UNCLASSIFIED\|Burkitt_lymphoma	p.E979G (No)	GDSC	BIBF-1120	149.2041
SIDM00948	UNCLASSIFIED\|Burkitt_lymphoma	p.E979G (No)	GDSC	Axitinib	10.3096
SIDM00948	UNCLASSIFIED\|Burkitt_lymphoma	p.E979G (No)	GDSC	Motesanib	15.9469
SIDM00948	UNCLASSIFIED\|Burkitt_lymphoma	p.E979G (No)	GDSC	Sorafenib	6.0739
SIDM00948	UNCLASSIFIED\|Burkitt_lymphoma	p.E979G (No)	GDSC	Cediranib	8.2906
SIDM00948	UNCLASSIFIED\|Burkitt_lymphoma	p.E979G (No)	GDSC	Foretinib	1.8461
SIDM01120	UNCLASSIFIED\|lung_NSCLC_carcinoid	p.S310A (No)	GDSC	Sunitinib	96.5078
SIDM01120	UNCLASSIFIED\|lung_NSCLC_carcinoid	p.S310A (No)	GDSC	Sorafenib	10.2261
SIDM01120	UNCLASSIFIED\|lung_NSCLC_carcinoid	p.S310A (No)	GDSC	Ponatinib	10.2267
SIDM01120	UNCLASSIFIED\|lung_NSCLC_carcinoid	p.S310A (No)	GDSC	Cabozantinib	102.8585
SIDM01120	UNCLASSIFIED\|lung_NSCLC_carcinoid	p.S310A (No)	GDSC	Linifanib	20.6363
SIDM01120	UNCLASSIFIED\|lung_NSCLC_carcinoid	p.S310A (No)	GDSC	Foretinib	2.4959
SIDM01120	UNCLASSIFIED\|lung_NSCLC_carcinoid	p.S310A (No)	GDSC	Tivozanib	2.1854
SIDM01120	UNCLASSIFIED\|lung_NSCLC_carcinoid	p.S310A (No)	GDSC	Brivanib, BMS-540215	55.9392
SIDM01120	UNCLASSIFIED\|lung_NSCLC_carcinoid	p.S310A (No)	GDSC	BIBF-1120	8.7862
SIDM01120	UNCLASSIFIED\|lung_NSCLC_carcinoid	p.S310A (No)	GDSC	Axitinib	3.8457
SIDM01120	UNCLASSIFIED\|lung_NSCLC_carcinoid	p.S310A (No)	GDSC	Motesanib	6.7148
SIDM01120	UNCLASSIFIED\|lung_NSCLC_carcinoid	p.S310A (No)	GDSC	Sorafenib	8.8176
SIDM01120	UNCLASSIFIED\|lung_NSCLC_carcinoid	p.S310A (No)	GDSC	Cediranib	13.265
SIDM01120	UNCLASSIFIED\|lung_NSCLC_carcinoid	p.S310A (No)	GDSC	Foretinib	1.636
SIDM00352	UNCLASSIFIED\|ovary	p.G99A (No)	GDSC	Ponatinib	8.745
SIDM00352	UNCLASSIFIED\|ovary	p.G99A (No)	GDSC	Cabozantinib	12.6272
SIDM00352	UNCLASSIFIED\|ovary	p.G99A (No)	GDSC	Linifanib	20.7968
SIDM00352	UNCLASSIFIED\|ovary	p.G99A (No)	GDSC	Foretinib	1.1638
SIDM00352	UNCLASSIFIED\|ovary	p.G99A (No)	GDSC	Tivozanib	2.0955
SIDM00352	UNCLASSIFIED\|ovary	p.G99A (No)	GDSC	Brivanib, BMS-540215	133.1914
SIDM00352	UNCLASSIFIED\|ovary	p.G99A (No)	GDSC	BIBF-1120	15.9989
SIDM00352	UNCLASSIFIED\|ovary	p.G99A (No)	GDSC	Axitinib	19.6861
SIDM00352	UNCLASSIFIED\|ovary	p.G99A (No)	GDSC	Sorafenib	67.14
SIDM00352	UNCLASSIFIED\|ovary	p.G99A (No)	GDSC	Cediranib	5.1561
SIDM00352	UNCLASSIFIED\|ovary	p.G99A (No)	GDSC	Foretinib	7.6524
SIDM01217	ALL\|leukemia	p.T1339I (No)	GDSC	Sunitinib	4.5223
SIDM01217	ALL\|leukemia	p.T1339I (No)	GDSC	Sorafenib	2.2196
SIDM01217	ALL\|leukemia	p.T1339I (No)	GDSC	Ponatinib	0.0022
SIDM01217	ALL\|leukemia	p.T1339I (No)	GDSC	Cabozantinib	0.3281
SIDM01217	ALL\|leukemia	p.T1339I (No)	GDSC	Linifanib	11.3611
SIDM01217	ALL\|leukemia	p.T1339I (No)	GDSC	Foretinib	0.1495
SIDM01217	ALL\|leukemia	p.T1339I (No)	GDSC	Tivozanib	0.0187
SIDM01217	ALL\|leukemia	p.T1339I (No)	GDSC	Brivanib, BMS-540215	12.6222
SIDM01217	ALL\|leukemia	p.T1339I (No)	GDSC	BIBF-1120	0.611
SIDM01217	ALL\|leukemia	p.T1339I (No)	GDSC	Axitinib	0.5387
SIDM01217	ALL\|leukemia	p.T1339I (No)	GDSC	Motesanib	21.6035
SIDM00216	COREAD\|large_intestine	p.S153T (No)	GDSC	Cabozantinib	6.0987
SIDM00216	COREAD\|large_intestine	p.S153T (No)	GDSC	Linifanib	6.5206
SIDM00216	COREAD\|large_intestine	p.S153T (No)	GDSC	Foretinib	0.3489
SIDM00216	COREAD\|large_intestine	p.S153T (No)	GDSC	Tivozanib	0.889
SIDM00216	COREAD\|large_intestine	p.S153T (No)	GDSC	Brivanib, BMS-540215	44.5765
SIDM00216	COREAD\|large_intestine	p.S153T (No)	GDSC	BIBF-1120	5.408
SIDM00216	COREAD\|large_intestine	p.S153T (No)	GDSC	Sorafenib	7.7286
SIDM00216	COREAD\|large_intestine	p.S153T (No)	GDSC	Cediranib	4.8238
SIDM00216	COREAD\|large_intestine	p.S153T (No)	GDSC	Foretinib	0.4705
SIDM00282	COREAD\|large_intestine	p.H1213Q (No)	GDSC	Sunitinib	189.499
SIDM00282	COREAD\|large_intestine	p.H1213Q (No)	GDSC	Sorafenib	61.3342
SIDM00282	COREAD\|large_intestine	p.H1213Q (No)	GDSC	Ponatinib	13.9216
SIDM00282	COREAD\|large_intestine	p.H1213Q (No)	GDSC	Cabozantinib	55.7164
SIDM00282	COREAD\|large_intestine	p.H1213Q (No)	GDSC	Linifanib	26.1518
SIDM00282	COREAD\|large_intestine	p.H1213Q (No)	GDSC	Foretinib	7.5179
SIDM00282	COREAD\|large_intestine	p.H1213Q (No)	GDSC	Tivozanib	2.4116
SIDM00282	COREAD\|large_intestine	p.H1213Q (No)	GDSC	Brivanib, BMS-540215	66.1763
SIDM00282	COREAD\|large_intestine	p.H1213Q (No)	GDSC	BIBF-1120	39.5796
SIDM00282	COREAD\|large_intestine	p.H1213Q (No)	GDSC	Axitinib	50.4847
SIDM00282	COREAD\|large_intestine	p.H1213Q (No)	GDSC	Motesanib	57.5889
SIDM00282	COREAD\|large_intestine	p.H1213Q (No)	GDSC	Sorafenib	7.9982
SIDM00282	COREAD\|large_intestine	p.H1213Q (No)	GDSC	Cediranib	11.404
SIDM00282	COREAD\|large_intestine	p.H1213Q (No)	GDSC	Foretinib	8.0375
SIDM00282	COREAD\|large_intestine	p.I915T (No)	GDSC	Sunitinib	189.499
SIDM00282	COREAD\|large_intestine	p.I915T (No)	GDSC	Sorafenib	61.3342
SIDM00282	COREAD\|large_intestine	p.I915T (No)	GDSC	Ponatinib	13.9216
SIDM00282	COREAD\|large_intestine	p.I915T (No)	GDSC	Cabozantinib	55.7164
SIDM00282	COREAD\|large_intestine	p.I915T (No)	GDSC	Linifanib	26.1518
SIDM00282	COREAD\|large_intestine	p.I915T (No)	GDSC	Foretinib	7.5179
SIDM00282	COREAD\|large_intestine	p.I915T (No)	GDSC	Tivozanib	2.4116
SIDM00282	COREAD\|large_intestine	p.I915T (No)	GDSC	Brivanib, BMS-540215	66.1763
SIDM00282	COREAD\|large_intestine	p.I915T (No)	GDSC	BIBF-1120	39.5796
SIDM00282	COREAD\|large_intestine	p.I915T (No)	GDSC	Axitinib	50.4847
SIDM00282	COREAD\|large_intestine	p.I915T (No)	GDSC	Motesanib	57.5889
SIDM00282	COREAD\|large_intestine	p.I915T (No)	GDSC	Sorafenib	7.9982
SIDM00282	COREAD\|large_intestine	p.I915T (No)	GDSC	Cediranib	11.404
SIDM00282	COREAD\|large_intestine	p.I915T (No)	GDSC	Foretinib	8.0375
SIDM00282	COREAD\|large_intestine	p.G424D (No)	GDSC	Sunitinib	189.499
SIDM00282	COREAD\|large_intestine	p.G424D (No)	GDSC	Sorafenib	61.3342
SIDM00282	COREAD\|large_intestine	p.G424D (No)	GDSC	Ponatinib	13.9216
SIDM00282	COREAD\|large_intestine	p.G424D (No)	GDSC	Cabozantinib	55.7164
SIDM00282	COREAD\|large_intestine	p.G424D (No)	GDSC	Linifanib	26.1518
SIDM00282	COREAD\|large_intestine	p.G424D (No)	GDSC	Foretinib	7.5179
SIDM00282	COREAD\|large_intestine	p.G424D (No)	GDSC	Tivozanib	2.4116
SIDM00282	COREAD\|large_intestine	p.G424D (No)	GDSC	Brivanib, BMS-540215	66.1763
SIDM00282	COREAD\|large_intestine	p.G424D (No)	GDSC	BIBF-1120	39.5796
SIDM00282	COREAD\|large_intestine	p.G424D (No)	GDSC	Axitinib	50.4847
SIDM00282	COREAD\|large_intestine	p.G424D (No)	GDSC	Motesanib	57.5889
SIDM00282	COREAD\|large_intestine	p.G424D (No)	GDSC	Sorafenib	7.9982
SIDM00282	COREAD\|large_intestine	p.G424D (No)	GDSC	Cediranib	11.404
SIDM00282	COREAD\|large_intestine	p.G424D (No)	GDSC	Foretinib	8.0375
SIDM00479	ESCA\|oesophagus	p.G539R (No)	GDSC	Ponatinib	10.0449
SIDM00479	ESCA\|oesophagus	p.G539R (No)	GDSC	Cabozantinib	100.1288
SIDM00479	ESCA\|oesophagus	p.G539R (No)	GDSC	Linifanib	17.5004
SIDM00479	ESCA\|oesophagus	p.G539R (No)	GDSC	Foretinib	6.6399
SIDM00479	ESCA\|oesophagus	p.G539R (No)	GDSC	Tivozanib	2.5112
SIDM00479	ESCA\|oesophagus	p.G539R (No)	GDSC	Brivanib, BMS-540215	327.6841
SIDM00479	ESCA\|oesophagus	p.G539R (No)	GDSC	BIBF-1120	3.4766
SIDM00479	ESCA\|oesophagus	p.G539R (No)	GDSC	Axitinib	6.6269
SIDM00479	ESCA\|oesophagus	p.G539R (No)	GDSC	Motesanib	11.2899
SIDM00479	ESCA\|oesophagus	p.G539R (No)	GDSC	Sorafenib	10.44
SIDM00479	ESCA\|oesophagus	p.G539R (No)	GDSC	Cediranib	5.5196
SIDM00479	ESCA\|oesophagus	p.G539R (No)	GDSC	Foretinib	1.9328
SIDM00150	COREAD\|large_intestine	p.S26G (No)	GDSC	Sunitinib	0.4368
SIDM00150	COREAD\|large_intestine	p.S26G (No)	GDSC	Sorafenib	0.9119
SIDM00150	COREAD\|large_intestine	p.S26G (No)	GDSC	Ponatinib	0.1197
SIDM00150	COREAD\|large_intestine	p.S26G (No)	GDSC	Cabozantinib	2.0837
SIDM00150	COREAD\|large_intestine	p.S26G (No)	GDSC	Linifanib	8.0753
SIDM00150	COREAD\|large_intestine	p.S26G (No)	GDSC	Foretinib	0.4609
SIDM00150	COREAD\|large_intestine	p.S26G (No)	GDSC	Tivozanib	0.604
SIDM00150	COREAD\|large_intestine	p.S26G (No)	GDSC	Brivanib, BMS-540215	73.4735
SIDM00150	COREAD\|large_intestine	p.S26G (No)	GDSC	BIBF-1120	2.5739
SIDM00150	COREAD\|large_intestine	p.S26G (No)	GDSC	Axitinib	7.6527
SIDM00150	COREAD\|large_intestine	p.S26G (No)	GDSC	Motesanib	31.6936
SIDM00150	COREAD\|large_intestine	p.S26G (No)	GDSC	Sorafenib	6.2706
SIDM00150	COREAD\|large_intestine	p.S26G (No)	GDSC	Cediranib	9.8117
SIDM00150	COREAD\|large_intestine	p.S26G (No)	GDSC	Foretinib	0.0941
SIDM01084	UNCLASSIFIED\|osteosarcoma	p.G671E (No)	GDSC	Ponatinib	5.8749
SIDM01084	UNCLASSIFIED\|osteosarcoma	p.G671E (No)	GDSC	Cabozantinib	153.8741
SIDM01084	UNCLASSIFIED\|osteosarcoma	p.G671E (No)	GDSC	Linifanib	30.0118
SIDM01084	UNCLASSIFIED\|osteosarcoma	p.G671E (No)	GDSC	Foretinib	153.8741
SIDM01084	UNCLASSIFIED\|osteosarcoma	p.G671E (No)	GDSC	Tivozanib	3.8117
SIDM01084	UNCLASSIFIED\|osteosarcoma	p.G671E (No)	GDSC	Brivanib, BMS-540215	106.3503
SIDM01084	UNCLASSIFIED\|osteosarcoma	p.G671E (No)	GDSC	BIBF-1120	2.6491
SIDM01084	UNCLASSIFIED\|osteosarcoma	p.G671E (No)	GDSC	Axitinib	23.5688
SIDM01084	UNCLASSIFIED\|osteosarcoma	p.G671E (No)	GDSC	Motesanib	49.9606
SIDM01084	UNCLASSIFIED\|osteosarcoma	p.G671E (No)	GDSC	Sorafenib	30.643
SIDM01084	UNCLASSIFIED\|osteosarcoma	p.G671E (No)	GDSC	Cediranib	96.887
SIDM01084	UNCLASSIFIED\|osteosarcoma	p.G671E (No)	GDSC	Foretinib	3.666
SIDM00640	MESO\|mesothelioma	p.S1303N (No)	GDSC	Sunitinib	13.3382
SIDM00640	MESO\|mesothelioma	p.S1303N (No)	GDSC	Sorafenib	19.1682
SIDM00640	MESO\|mesothelioma	p.S1303N (No)	GDSC	Ponatinib	5.1901
SIDM00640	MESO\|mesothelioma	p.S1303N (No)	GDSC	Cabozantinib	43.5058
SIDM00640	MESO\|mesothelioma	p.S1303N (No)	GDSC	Linifanib	5.9476
SIDM00640	MESO\|mesothelioma	p.S1303N (No)	GDSC	Foretinib	4.6612
SIDM00640	MESO\|mesothelioma	p.S1303N (No)	GDSC	Tivozanib	1.2658
SIDM00640	MESO\|mesothelioma	p.S1303N (No)	GDSC	Brivanib, BMS-540215	19.0818
SIDM00640	MESO\|mesothelioma	p.S1303N (No)	GDSC	BIBF-1120	2.603
SIDM00640	MESO\|mesothelioma	p.S1303N (No)	GDSC	Axitinib	7.0831
SIDM00640	MESO\|mesothelioma	p.S1303N (No)	GDSC	Motesanib	20.8095
SIDM00640	MESO\|mesothelioma	p.S1303N (No)	GDSC	Sorafenib	5.569
SIDM00640	MESO\|mesothelioma	p.S1303N (No)	GDSC	Cediranib	11.504
SIDM00640	MESO\|mesothelioma	p.S1303N (No)	GDSC	Foretinib	4.8957
SIDM00715	LUAD\|lung_NSCLC_adenocarcinoma	p.G152V (No)	GDSC	Ponatinib	0.2621
SIDM00715	LUAD\|lung_NSCLC_adenocarcinoma	p.G152V (No)	GDSC	Cabozantinib	14.9572
SIDM00715	LUAD\|lung_NSCLC_adenocarcinoma	p.G152V (No)	GDSC	Linifanib	10.2624
SIDM00715	LUAD\|lung_NSCLC_adenocarcinoma	p.G152V (No)	GDSC	Foretinib	0.7612
SIDM00715	LUAD\|lung_NSCLC_adenocarcinoma	p.G152V (No)	GDSC	Tivozanib	1.3803
SIDM00715	LUAD\|lung_NSCLC_adenocarcinoma	p.G152V (No)	GDSC	Brivanib, BMS-540215	121.4884
SIDM00715	LUAD\|lung_NSCLC_adenocarcinoma	p.G152V (No)	GDSC	BIBF-1120	14.4091
SIDM00715	LUAD\|lung_NSCLC_adenocarcinoma	p.G152V (No)	GDSC	Axitinib	26.8735
SIDM00715	LUAD\|lung_NSCLC_adenocarcinoma	p.G152V (No)	GDSC	Motesanib	7.629
SIDM01183	UNCLASSIFIED\|lung_NSCLC_carcinoid	p.D1064Y (No)	GDSC	Ponatinib	6.5232
SIDM01183	UNCLASSIFIED\|lung_NSCLC_carcinoid	p.D1064Y (No)	GDSC	Cabozantinib	6.5099
SIDM01183	UNCLASSIFIED\|lung_NSCLC_carcinoid	p.D1064Y (No)	GDSC	Linifanib	9.2766
SIDM01183	UNCLASSIFIED\|lung_NSCLC_carcinoid	p.D1064Y (No)	GDSC	Foretinib	0.706
SIDM01183	UNCLASSIFIED\|lung_NSCLC_carcinoid	p.D1064Y (No)	GDSC	Tivozanib	1.133
SIDM01183	UNCLASSIFIED\|lung_NSCLC_carcinoid	p.D1064Y (No)	GDSC	Brivanib, BMS-540215	20.668
SIDM01183	UNCLASSIFIED\|lung_NSCLC_carcinoid	p.D1064Y (No)	GDSC	BIBF-1120	6.0099
SIDM01183	UNCLASSIFIED\|lung_NSCLC_carcinoid	p.D1064Y (No)	GDSC	Axitinib	3.5098
SIDM01183	UNCLASSIFIED\|lung_NSCLC_carcinoid	p.D1064Y (No)	GDSC	Motesanib	3.3372
SIDM01183	UNCLASSIFIED\|lung_NSCLC_carcinoid	p.D1064Y (No)	GDSC	Sorafenib	6.9458
SIDM01183	UNCLASSIFIED\|lung_NSCLC_carcinoid	p.D1064Y (No)	GDSC	Cediranib	6.8927
SIDM01183	UNCLASSIFIED\|lung_NSCLC_carcinoid	p.D1064Y (No)	GDSC	Foretinib	2.3879
SIDM00954	BRCA\|breast	p.R106W (No)	GDSC	Sunitinib	39.9798
SIDM00954	BRCA\|breast	p.R106W (No)	GDSC	Sorafenib	14.6424
SIDM00954	BRCA\|breast	p.R106W (No)	GDSC	Ponatinib	5.6122
SIDM00954	BRCA\|breast	p.R106W (No)	GDSC	Cabozantinib	9.7866
SIDM00954	BRCA\|breast	p.R106W (No)	GDSC	Linifanib	9.8819
SIDM00954	BRCA\|breast	p.R106W (No)	GDSC	Foretinib	1.3792
SIDM00954	BRCA\|breast	p.R106W (No)	GDSC	Tivozanib	1.6792
SIDM00954	BRCA\|breast	p.R106W (No)	GDSC	Brivanib, BMS-540215	108.4196
SIDM00954	BRCA\|breast	p.R106W (No)	GDSC	BIBF-1120	5.8337
SIDM00954	BRCA\|breast	p.R106W (No)	GDSC	Axitinib	28.417
SIDM00954	BRCA\|breast	p.R106W (No)	GDSC	Motesanib	31.2238
SIDM00954	BRCA\|breast	p.R106W (No)	GDSC	Axitinib	8.7656
SIDM00954	BRCA\|breast	p.R106W (No)	GDSC	Sorafenib	16.898
SIDM00954	BRCA\|breast	p.R106W (No)	GDSC	Cediranib	8.2377
SIDM00954	BRCA\|breast	p.R106W (No)	GDSC	Foretinib	0.8825
SIDM00422	UNCLASSIFIED\|Hodgkin_lymphoma	p.V1207E (No)	GDSC	Sunitinib	4.3538
SIDM00422	UNCLASSIFIED\|Hodgkin_lymphoma	p.V1207E (No)	GDSC	Sorafenib	4.3968
SIDM00422	UNCLASSIFIED\|Hodgkin_lymphoma	p.V1207E (No)	GDSC	Ponatinib	2.0749
SIDM00422	UNCLASSIFIED\|Hodgkin_lymphoma	p.V1207E (No)	GDSC	Cabozantinib	11.4291
SIDM00422	UNCLASSIFIED\|Hodgkin_lymphoma	p.V1207E (No)	GDSC	Linifanib	9.6852
SIDM00422	UNCLASSIFIED\|Hodgkin_lymphoma	p.V1207E (No)	GDSC	Foretinib	0.8607
SIDM00422	UNCLASSIFIED\|Hodgkin_lymphoma	p.V1207E (No)	GDSC	Tivozanib	1.2222
SIDM00422	UNCLASSIFIED\|Hodgkin_lymphoma	p.V1207E (No)	GDSC	Brivanib, BMS-540215	25.7971
SIDM00422	UNCLASSIFIED\|Hodgkin_lymphoma	p.V1207E (No)	GDSC	BIBF-1120	21.4575
SIDM00422	UNCLASSIFIED\|Hodgkin_lymphoma	p.V1207E (No)	GDSC	Axitinib	4.3721
SIDM00422	UNCLASSIFIED\|Hodgkin_lymphoma	p.V1207E (No)	GDSC	Motesanib	16.2033
SIDM00422	UNCLASSIFIED\|Hodgkin_lymphoma	p.V1207E (No)	GDSC	Sorafenib	13.447
SIDM00422	UNCLASSIFIED\|Hodgkin_lymphoma	p.V1207E (No)	GDSC	Cediranib	31.636
SIDM00422	UNCLASSIFIED\|Hodgkin_lymphoma	p.V1207E (No)	GDSC	Foretinib	2.3568
SIDM00789	COREAD\|large_intestine	p.S925F (No)	GDSC	Ponatinib	1.6564
SIDM00789	COREAD\|large_intestine	p.S925F (No)	GDSC	Cabozantinib	14.2209
SIDM00789	COREAD\|large_intestine	p.S925F (No)	GDSC	Linifanib	9.391
SIDM00789	COREAD\|large_intestine	p.S925F (No)	GDSC	Foretinib	0.9916
SIDM00789	COREAD\|large_intestine	p.S925F (No)	GDSC	Tivozanib	1.3233
SIDM00789	COREAD\|large_intestine	p.S925F (No)	GDSC	Brivanib, BMS-540215	54.9229
SIDM00789	COREAD\|large_intestine	p.S925F (No)	GDSC	BIBF-1120	90.8873
SIDM00789	COREAD\|large_intestine	p.S925F (No)	GDSC	Axitinib	7.279
SIDM00789	COREAD\|large_intestine	p.S925F (No)	GDSC	Motesanib	12.7822
SIDM00789	COREAD\|large_intestine	p.S925F (No)	GDSC	Sorafenib	10.469
SIDM00789	COREAD\|large_intestine	p.S925F (No)	GDSC	Cediranib	6.0229
SIDM00789	COREAD\|large_intestine	p.S925F (No)	GDSC	Foretinib	2.3277
SIDM00534	COREAD\|large_intestine	p.D1312N (No)	GDSC	Ponatinib	6.8973
SIDM00534	COREAD\|large_intestine	p.D1312N (No)	GDSC	Cabozantinib	34.719
SIDM00534	COREAD\|large_intestine	p.D1312N (No)	GDSC	Linifanib	13.547
SIDM00534	COREAD\|large_intestine	p.D1312N (No)	GDSC	Foretinib	4.5289
SIDM00534	COREAD\|large_intestine	p.D1312N (No)	GDSC	Tivozanib	1.7085
SIDM00534	COREAD\|large_intestine	p.D1312N (No)	GDSC	Brivanib, BMS-540215	95.0311
SIDM00534	COREAD\|large_intestine	p.D1312N (No)	GDSC	BIBF-1120	20.297
SIDM00534	COREAD\|large_intestine	p.D1312N (No)	GDSC	Axitinib	7.3465
SIDM00534	COREAD\|large_intestine	p.D1312N (No)	GDSC	Motesanib	18.0454
SIDM00534	COREAD\|large_intestine	p.S1290N (No)	GDSC	Ponatinib	6.8973
SIDM00534	COREAD\|large_intestine	p.S1290N (No)	GDSC	Cabozantinib	34.719
SIDM00534	COREAD\|large_intestine	p.S1290N (No)	GDSC	Linifanib	13.547
SIDM00534	COREAD\|large_intestine	p.S1290N (No)	GDSC	Foretinib	4.5289
SIDM00534	COREAD\|large_intestine	p.S1290N (No)	GDSC	Tivozanib	1.7085
SIDM00534	COREAD\|large_intestine	p.S1290N (No)	GDSC	Brivanib, BMS-540215	95.0311
SIDM00534	COREAD\|large_intestine	p.S1290N (No)	GDSC	BIBF-1120	20.297
SIDM00534	COREAD\|large_intestine	p.S1290N (No)	GDSC	Axitinib	7.3465
SIDM00534	COREAD\|large_intestine	p.S1290N (No)	GDSC	Motesanib	18.0454
SIDM00534	COREAD\|large_intestine	p.R944Q (No)	GDSC	Ponatinib	6.8973
SIDM00534	COREAD\|large_intestine	p.R944Q (No)	GDSC	Cabozantinib	34.719
SIDM00534	COREAD\|large_intestine	p.R944Q (No)	GDSC	Linifanib	13.547
SIDM00534	COREAD\|large_intestine	p.R944Q (No)	GDSC	Foretinib	4.5289
SIDM00534	COREAD\|large_intestine	p.R944Q (No)	GDSC	Tivozanib	1.7085
SIDM00534	COREAD\|large_intestine	p.R944Q (No)	GDSC	Brivanib, BMS-540215	95.0311
SIDM00534	COREAD\|large_intestine	p.R944Q (No)	GDSC	BIBF-1120	20.297
SIDM00534	COREAD\|large_intestine	p.R944Q (No)	GDSC	Axitinib	7.3465
SIDM00534	COREAD\|large_intestine	p.R944Q (No)	GDSC	Motesanib	18.0454
SIDM01175	UNCLASSIFIED\|fibrosarcoma	p.G942E (No)	GDSC	Sunitinib	336.6649
SIDM01175	UNCLASSIFIED\|fibrosarcoma	p.G942E (No)	GDSC	Sorafenib	168.3325
SIDM01175	UNCLASSIFIED\|fibrosarcoma	p.G942E (No)	GDSC	Ponatinib	17.9617
SIDM01175	UNCLASSIFIED\|fibrosarcoma	p.G942E (No)	GDSC	Cabozantinib	215.4655
SIDM01175	UNCLASSIFIED\|fibrosarcoma	p.G942E (No)	GDSC	Linifanib	41.3801
SIDM01175	UNCLASSIFIED\|fibrosarcoma	p.G942E (No)	GDSC	Foretinib	215.4655
SIDM01175	UNCLASSIFIED\|fibrosarcoma	p.G942E (No)	GDSC	Tivozanib	4.3501
SIDM01175	UNCLASSIFIED\|fibrosarcoma	p.G942E (No)	GDSC	Brivanib, BMS-540215	344.8377
SIDM01175	UNCLASSIFIED\|fibrosarcoma	p.G942E (No)	GDSC	BIBF-1120	35.6694
SIDM01175	UNCLASSIFIED\|fibrosarcoma	p.G942E (No)	GDSC	Axitinib	84.1662
SIDM01175	UNCLASSIFIED\|fibrosarcoma	p.G942E (No)	GDSC	Motesanib	84.1662
SIDM01175	UNCLASSIFIED\|fibrosarcoma	p.G942E (No)	GDSC	Sorafenib	120.66
SIDM01175	UNCLASSIFIED\|fibrosarcoma	p.G942E (No)	GDSC	Cediranib	138.91
SIDM01175	UNCLASSIFIED\|fibrosarcoma	p.G942E (No)	GDSC	Foretinib	6.4082
SIDM01175	UNCLASSIFIED\|fibrosarcoma	p.P839S (No)	GDSC	Sunitinib	336.6649
SIDM01175	UNCLASSIFIED\|fibrosarcoma	p.P839S (No)	GDSC	Sorafenib	168.3325
SIDM01175	UNCLASSIFIED\|fibrosarcoma	p.P839S (No)	GDSC	Ponatinib	17.9617
SIDM01175	UNCLASSIFIED\|fibrosarcoma	p.P839S (No)	GDSC	Cabozantinib	215.4655
SIDM01175	UNCLASSIFIED\|fibrosarcoma	p.P839S (No)	GDSC	Linifanib	41.3801
SIDM01175	UNCLASSIFIED\|fibrosarcoma	p.P839S (No)	GDSC	Foretinib	215.4655
SIDM01175	UNCLASSIFIED\|fibrosarcoma	p.P839S (No)	GDSC	Tivozanib	4.3501
SIDM01175	UNCLASSIFIED\|fibrosarcoma	p.P839S (No)	GDSC	Brivanib, BMS-540215	344.8377
SIDM01175	UNCLASSIFIED\|fibrosarcoma	p.P839S (No)	GDSC	BIBF-1120	35.6694
SIDM01175	UNCLASSIFIED\|fibrosarcoma	p.P839S (No)	GDSC	Axitinib	84.1662
SIDM01175	UNCLASSIFIED\|fibrosarcoma	p.P839S (No)	GDSC	Motesanib	84.1662
SIDM01175	UNCLASSIFIED\|fibrosarcoma	p.P839S (No)	GDSC	Sorafenib	120.66
SIDM01175	UNCLASSIFIED\|fibrosarcoma	p.P839S (No)	GDSC	Cediranib	138.91
SIDM01175	UNCLASSIFIED\|fibrosarcoma	p.P839S (No)	GDSC	Foretinib	6.4082
SIDM00245	SCLC\|lung_small_cell_carcinoma	p.T660P (No)	GDSC	Sunitinib	3.5046
SIDM00245	SCLC\|lung_small_cell_carcinoma	p.T660P (No)	GDSC	Sorafenib	17.0004
SIDM00245	SCLC\|lung_small_cell_carcinoma	p.T660P (No)	GDSC	Ponatinib	1.5918
SIDM00245	SCLC\|lung_small_cell_carcinoma	p.T660P (No)	GDSC	Cabozantinib	16.1575
SIDM00245	SCLC\|lung_small_cell_carcinoma	p.T660P (No)	GDSC	Linifanib	8.498
SIDM00245	SCLC\|lung_small_cell_carcinoma	p.T660P (No)	GDSC	Foretinib	0.5605
SIDM00245	SCLC\|lung_small_cell_carcinoma	p.T660P (No)	GDSC	Tivozanib	1.2581
SIDM00245	SCLC\|lung_small_cell_carcinoma	p.T660P (No)	GDSC	Brivanib, BMS-540215	26.0028
SIDM00245	SCLC\|lung_small_cell_carcinoma	p.T660P (No)	GDSC	BIBF-1120	3.0891
SIDM00245	SCLC\|lung_small_cell_carcinoma	p.T660P (No)	GDSC	Axitinib	7.9138
SIDM00245	SCLC\|lung_small_cell_carcinoma	p.T660P (No)	GDSC	Motesanib	12.8484
SIDM00245	SCLC\|lung_small_cell_carcinoma	p.T660P (No)	GDSC	Sorafenib	5.503
SIDM00245	SCLC\|lung_small_cell_carcinoma	p.T660P (No)	GDSC	Cediranib	5.8685
SIDM00245	SCLC\|lung_small_cell_carcinoma	p.T660P (No)	GDSC	Foretinib	3.1113
SIDM01220	GBM\|glioma	p.L707I (No)	GDSC	Ponatinib	0.5541
SIDM01220	GBM\|glioma	p.L707I (No)	GDSC	Cabozantinib	14.0564
SIDM01220	GBM\|glioma	p.L707I (No)	GDSC	Linifanib	11.3852
SIDM01220	GBM\|glioma	p.L707I (No)	GDSC	Foretinib	1.7942
SIDM01220	GBM\|glioma	p.L707I (No)	GDSC	Tivozanib	1.4303
SIDM01220	GBM\|glioma	p.L707I (No)	GDSC	Brivanib, BMS-540215	72.3833
SIDM01220	GBM\|glioma	p.L707I (No)	GDSC	BIBF-1120	72.1527
SIDM01220	GBM\|glioma	p.L707I (No)	GDSC	Axitinib	3.8696
SIDM01220	GBM\|glioma	p.L707I (No)	GDSC	Motesanib	14.2845
SIDM00735	SCLC\|lung_small_cell_carcinoma	p.K939R (No)	GDSC	Ponatinib	5.945
SIDM00735	SCLC\|lung_small_cell_carcinoma	p.K939R (No)	GDSC	Cabozantinib	55.1183
SIDM00735	SCLC\|lung_small_cell_carcinoma	p.K939R (No)	GDSC	Linifanib	11.8852
SIDM00735	SCLC\|lung_small_cell_carcinoma	p.K939R (No)	GDSC	Foretinib	2.3243
SIDM00735	SCLC\|lung_small_cell_carcinoma	p.K939R (No)	GDSC	Tivozanib	1.487
SIDM00735	SCLC\|lung_small_cell_carcinoma	p.K939R (No)	GDSC	Brivanib, BMS-540215	72.109
SIDM00735	SCLC\|lung_small_cell_carcinoma	p.K939R (No)	GDSC	BIBF-1120	18.5397
SIDM00735	SCLC\|lung_small_cell_carcinoma	p.K939R (No)	GDSC	Axitinib	5.4859
SIDM00735	SCLC\|lung_small_cell_carcinoma	p.K939R (No)	GDSC	Motesanib	15.2917
SIDM00735	SCLC\|lung_small_cell_carcinoma	p.K939R (No)	GDSC	Foretinib	4.8586
SIDM00545	SKCM\|melanoma	p.S1281F (No)	GDSC	Ponatinib	12.0185
SIDM00545	SKCM\|melanoma	p.S1281F (No)	GDSC	Cabozantinib	107.4008
SIDM00545	SKCM\|melanoma	p.S1281F (No)	GDSC	Linifanib	18.6537
SIDM00545	SKCM\|melanoma	p.S1281F (No)	GDSC	Foretinib	5.4278
SIDM00545	SKCM\|melanoma	p.S1281F (No)	GDSC	Tivozanib	2.2473
SIDM00545	SKCM\|melanoma	p.S1281F (No)	GDSC	Brivanib, BMS-540215	290.7788
SIDM00545	SKCM\|melanoma	p.S1281F (No)	GDSC	BIBF-1120	25.7926
SIDM00545	SKCM\|melanoma	p.S1281F (No)	GDSC	Axitinib	39.1958
SIDM00545	SKCM\|melanoma	p.S1281F (No)	GDSC	Motesanib	13.0462
SIDM00545	SKCM\|melanoma	p.S1281F (No)	GDSC	Sorafenib	22.398
SIDM00545	SKCM\|melanoma	p.S1281F (No)	GDSC	Cediranib	9.5587
SIDM00545	SKCM\|melanoma	p.S1281F (No)	GDSC	Foretinib	4.0516
SIDM00120	PRAD\|prostate	p.C466F (No)	GDSC	Ponatinib	0.6979
SIDM00120	PRAD\|prostate	p.C466F (No)	GDSC	Cabozantinib	63.4851
SIDM00120	PRAD\|prostate	p.C466F (No)	GDSC	Linifanib	15.3008
SIDM00120	PRAD\|prostate	p.C466F (No)	GDSC	Foretinib	1.5628
SIDM00120	PRAD\|prostate	p.C466F (No)	GDSC	Tivozanib	2.0611
SIDM00120	PRAD\|prostate	p.C466F (No)	GDSC	Brivanib, BMS-540215	61.713
SIDM00120	PRAD\|prostate	p.C466F (No)	GDSC	BIBF-1120	38.9053
SIDM00120	PRAD\|prostate	p.C466F (No)	GDSC	Axitinib	2.2993
SIDM00120	PRAD\|prostate	p.C466F (No)	GDSC	Motesanib	0.5405
SIDM00120	PRAD\|prostate	p.C466F (No)	GDSC	Sorafenib	65.631
SIDM00120	PRAD\|prostate	p.C466F (No)	GDSC	Cediranib	86.136
SIDM00120	PRAD\|prostate	p.C466F (No)	GDSC	Foretinib	14.952
SIDM00114	MESO\|mesothelioma	p.P992S (No)	GDSC	Ponatinib	15.1296
SIDM00114	MESO\|mesothelioma	p.P992S (No)	GDSC	Cabozantinib	144.2481
SIDM00114	MESO\|mesothelioma	p.P992S (No)	GDSC	Linifanib	14.9174
SIDM00114	MESO\|mesothelioma	p.P992S (No)	GDSC	Foretinib	121.8592
SIDM00114	MESO\|mesothelioma	p.P992S (No)	GDSC	Tivozanib	2.653
SIDM00114	MESO\|mesothelioma	p.P992S (No)	GDSC	Brivanib, BMS-540215	391.7555
SIDM00114	MESO\|mesothelioma	p.P992S (No)	GDSC	BIBF-1120	110.2938
SIDM00114	MESO\|mesothelioma	p.P992S (No)	GDSC	Axitinib	58.0569
SIDM00114	MESO\|mesothelioma	p.P992S (No)	GDSC	Motesanib	58.0907
SIDM00114	MESO\|mesothelioma	p.P992S (No)	GDSC	Sorafenib	68.959
SIDM00114	MESO\|mesothelioma	p.P992S (No)	GDSC	Cediranib	28.532
SIDM00114	MESO\|mesothelioma	p.P992S (No)	GDSC	Foretinib	29.013
SIDM00114	MESO\|mesothelioma	p.N721K (No)	GDSC	Ponatinib	15.1296
SIDM00114	MESO\|mesothelioma	p.N721K (No)	GDSC	Cabozantinib	144.2481
SIDM00114	MESO\|mesothelioma	p.N721K (No)	GDSC	Linifanib	14.9174
SIDM00114	MESO\|mesothelioma	p.N721K (No)	GDSC	Foretinib	121.8592
SIDM00114	MESO\|mesothelioma	p.N721K (No)	GDSC	Tivozanib	2.653
SIDM00114	MESO\|mesothelioma	p.N721K (No)	GDSC	Brivanib, BMS-540215	391.7555
SIDM00114	MESO\|mesothelioma	p.N721K (No)	GDSC	BIBF-1120	110.2938
SIDM00114	MESO\|mesothelioma	p.N721K (No)	GDSC	Axitinib	58.0569
SIDM00114	MESO\|mesothelioma	p.N721K (No)	GDSC	Motesanib	58.0907
SIDM00114	MESO\|mesothelioma	p.N721K (No)	GDSC	Sorafenib	68.959
SIDM00114	MESO\|mesothelioma	p.N721K (No)	GDSC	Cediranib	28.532
SIDM00114	MESO\|mesothelioma	p.N721K (No)	GDSC	Foretinib	29.013
SIDM00949	UNCLASSIFIED\|lymphoid_neoplasm_other	p.G255R (No)	GDSC	Sunitinib	1.9017
SIDM00949	UNCLASSIFIED\|lymphoid_neoplasm_other	p.G255R (No)	GDSC	Sorafenib	2.3762
SIDM00949	UNCLASSIFIED\|lymphoid_neoplasm_other	p.G255R (No)	GDSC	Ponatinib	1.4001
SIDM00949	UNCLASSIFIED\|lymphoid_neoplasm_other	p.G255R (No)	GDSC	Cabozantinib	21.9398
SIDM00949	UNCLASSIFIED\|lymphoid_neoplasm_other	p.G255R (No)	GDSC	Linifanib	6.6504
SIDM00949	UNCLASSIFIED\|lymphoid_neoplasm_other	p.G255R (No)	GDSC	Foretinib	1.2469
SIDM00949	UNCLASSIFIED\|lymphoid_neoplasm_other	p.G255R (No)	GDSC	Tivozanib	0.5962
SIDM00949	UNCLASSIFIED\|lymphoid_neoplasm_other	p.G255R (No)	GDSC	Brivanib, BMS-540215	47.8914
SIDM00949	UNCLASSIFIED\|lymphoid_neoplasm_other	p.G255R (No)	GDSC	BIBF-1120	23.6798
SIDM00949	UNCLASSIFIED\|lymphoid_neoplasm_other	p.G255R (No)	GDSC	Axitinib	2.5424
SIDM00949	UNCLASSIFIED\|lymphoid_neoplasm_other	p.G255R (No)	GDSC	Motesanib	3.4761
SIDM00949	UNCLASSIFIED\|lymphoid_neoplasm_other	p.G255R (No)	GDSC	Sorafenib	4.0768
SIDM00949	UNCLASSIFIED\|lymphoid_neoplasm_other	p.G255R (No)	GDSC	Cediranib	2.119
SIDM00949	UNCLASSIFIED\|lymphoid_neoplasm_other	p.G255R (No)	GDSC	Foretinib	0.2497
SIDM00144	UNCLASSIFIED\|lung_NSCLC_large_cell	p.G1304C (No)	GDSC	Ponatinib	0.8208
SIDM00144	UNCLASSIFIED\|lung_NSCLC_large_cell	p.G1304C (No)	GDSC	Cabozantinib	44.1996
SIDM00144	UNCLASSIFIED\|lung_NSCLC_large_cell	p.G1304C (No)	GDSC	Linifanib	10.1372
SIDM00144	UNCLASSIFIED\|lung_NSCLC_large_cell	p.G1304C (No)	GDSC	Foretinib	2.7056
SIDM00144	UNCLASSIFIED\|lung_NSCLC_large_cell	p.G1304C (No)	GDSC	Tivozanib	1.3669
SIDM00144	UNCLASSIFIED\|lung_NSCLC_large_cell	p.G1304C (No)	GDSC	Brivanib, BMS-540215	84.5607
SIDM00144	UNCLASSIFIED\|lung_NSCLC_large_cell	p.G1304C (No)	GDSC	BIBF-1120	17.5181
SIDM00144	UNCLASSIFIED\|lung_NSCLC_large_cell	p.G1304C (No)	GDSC	Axitinib	3.3474
SIDM00144	UNCLASSIFIED\|lung_NSCLC_large_cell	p.G1304C (No)	GDSC	Motesanib	21.1764
SIDM00225	SKCM\|melanoma	p.M191I (No)	GDSC	Sunitinib	4.5073
SIDM00225	SKCM\|melanoma	p.M191I (No)	GDSC	Sorafenib	6.5871
SIDM00225	SKCM\|melanoma	p.M191I (No)	GDSC	Ponatinib	0.7424
SIDM00225	SKCM\|melanoma	p.M191I (No)	GDSC	Cabozantinib	23.0587
SIDM00225	SKCM\|melanoma	p.M191I (No)	GDSC	Linifanib	6.1171
SIDM00225	SKCM\|melanoma	p.M191I (No)	GDSC	Foretinib	0.4757
SIDM00225	SKCM\|melanoma	p.M191I (No)	GDSC	Tivozanib	2.2074
SIDM00225	SKCM\|melanoma	p.M191I (No)	GDSC	Brivanib, BMS-540215	114.9605
SIDM00225	SKCM\|melanoma	p.M191I (No)	GDSC	BIBF-1120	12.7982
SIDM00225	SKCM\|melanoma	p.M191I (No)	GDSC	Axitinib	15.7432
SIDM00225	SKCM\|melanoma	p.M191I (No)	GDSC	Motesanib	27.8266
SIDM00225	SKCM\|melanoma	p.M191I (No)	GDSC	Sorafenib	43.153
SIDM00225	SKCM\|melanoma	p.M191I (No)	GDSC	Cediranib	5.1844
SIDM00225	SKCM\|melanoma	p.M191I (No)	GDSC	Foretinib	3.7209
SIDM00451	ALL\|lymphoblastic_T_cell_leukaemia	p.R791Q (No)	GDSC	Sunitinib	2.8236
SIDM00451	ALL\|lymphoblastic_T_cell_leukaemia	p.R791Q (No)	GDSC	Sorafenib	5.9691
SIDM00451	ALL\|lymphoblastic_T_cell_leukaemia	p.R791Q (No)	GDSC	Ponatinib	0.1731
SIDM00451	ALL\|lymphoblastic_T_cell_leukaemia	p.R791Q (No)	GDSC	Cabozantinib	4.5922
SIDM00451	ALL\|lymphoblastic_T_cell_leukaemia	p.R791Q (No)	GDSC	Linifanib	9.659
SIDM00451	ALL\|lymphoblastic_T_cell_leukaemia	p.R791Q (No)	GDSC	Foretinib	0.3978
SIDM00451	ALL\|lymphoblastic_T_cell_leukaemia	p.R791Q (No)	GDSC	Tivozanib	0.679
SIDM00451	ALL\|lymphoblastic_T_cell_leukaemia	p.R791Q (No)	GDSC	Brivanib, BMS-540215	36.5429
SIDM00451	ALL\|lymphoblastic_T_cell_leukaemia	p.R791Q (No)	GDSC	BIBF-1120	1.6019
SIDM00451	ALL\|lymphoblastic_T_cell_leukaemia	p.R791Q (No)	GDSC	Axitinib	5.7949
SIDM00451	ALL\|lymphoblastic_T_cell_leukaemia	p.R791Q (No)	GDSC	Motesanib	10.1078
SIDM00451	ALL\|lymphoblastic_T_cell_leukaemia	p.R791Q (No)	GDSC	Sorafenib	2.3029
SIDM00451	ALL\|lymphoblastic_T_cell_leukaemia	p.R791Q (No)	GDSC	Cediranib	6.4664
SIDM00451	ALL\|lymphoblastic_T_cell_leukaemia	p.R791Q (No)	GDSC	Foretinib	0.6028
SIDM00726	LUAD\|lung_NSCLC_adenocarcinoma	p.S1266L (No)	GDSC	Ponatinib	0.9495
SIDM00726	LUAD\|lung_NSCLC_adenocarcinoma	p.S1266L (No)	GDSC	Cabozantinib	4.5532
SIDM00726	LUAD\|lung_NSCLC_adenocarcinoma	p.S1266L (No)	GDSC	Linifanib	10.0417
SIDM00726	LUAD\|lung_NSCLC_adenocarcinoma	p.S1266L (No)	GDSC	Foretinib	1.2213
SIDM00726	LUAD\|lung_NSCLC_adenocarcinoma	p.S1266L (No)	GDSC	Tivozanib	2.2374
SIDM00726	LUAD\|lung_NSCLC_adenocarcinoma	p.S1266L (No)	GDSC	Brivanib, BMS-540215	172.8152
SIDM00726	LUAD\|lung_NSCLC_adenocarcinoma	p.S1266L (No)	GDSC	BIBF-1120	12.2604
SIDM00726	LUAD\|lung_NSCLC_adenocarcinoma	p.S1266L (No)	GDSC	Axitinib	38.0394
SIDM00726	LUAD\|lung_NSCLC_adenocarcinoma	p.S1266L (No)	GDSC	Motesanib	34.3232
SIDM00726	LUAD\|lung_NSCLC_adenocarcinoma	p.S1266L (No)	GDSC	Sorafenib	176.57
SIDM00726	LUAD\|lung_NSCLC_adenocarcinoma	p.S1266L (No)	GDSC	Cediranib	93.26
SIDM00726	LUAD\|lung_NSCLC_adenocarcinoma	p.S1266L (No)	GDSC	Foretinib	95.098
SIDM00080	SKCM\|melanoma	p.S633F (No)	GDSC	Ponatinib	7.2627
SIDM00080	SKCM\|melanoma	p.S633F (No)	GDSC	Cabozantinib	17.7799
SIDM00080	SKCM\|melanoma	p.S633F (No)	GDSC	Linifanib	26.4944
SIDM00080	SKCM\|melanoma	p.S633F (No)	GDSC	Foretinib	1.7688
SIDM00080	SKCM\|melanoma	p.S633F (No)	GDSC	Tivozanib	4.029
SIDM00080	SKCM\|melanoma	p.S633F (No)	GDSC	Brivanib, BMS-540215	190.4419
SIDM00080	SKCM\|melanoma	p.S633F (No)	GDSC	BIBF-1120	17.7702
SIDM00080	SKCM\|melanoma	p.S633F (No)	GDSC	Axitinib	5.259
SIDM00080	SKCM\|melanoma	p.S633F (No)	GDSC	Motesanib	14.2751
SIDM00218	THCA\|thyroid	p.D173Y (No)	GDSC	Ponatinib	0.7801
SIDM00218	THCA\|thyroid	p.D173Y (No)	GDSC	Cabozantinib	42.429
SIDM00218	THCA\|thyroid	p.D173Y (No)	GDSC	Linifanib	22.5105
SIDM00218	THCA\|thyroid	p.D173Y (No)	GDSC	Foretinib	2.0655
SIDM00218	THCA\|thyroid	p.D173Y (No)	GDSC	Tivozanib	1.9378
SIDM00218	THCA\|thyroid	p.D173Y (No)	GDSC	Brivanib, BMS-540215	415.2646
SIDM00218	THCA\|thyroid	p.D173Y (No)	GDSC	BIBF-1120	62.4198
SIDM00218	THCA\|thyroid	p.D173Y (No)	GDSC	Axitinib	6.1561
SIDM00218	THCA\|thyroid	p.D173Y (No)	GDSC	Motesanib	6.275
SIDM00218	THCA\|thyroid	p.D173Y (No)	GDSC	Sorafenib	1743.4
SIDM00218	THCA\|thyroid	p.D173Y (No)	GDSC	Cediranib	135.55
SIDM00218	THCA\|thyroid	p.D173Y (No)	GDSC	Foretinib	11.667
SIDM00580	LAML\|acute_myeloid_leukaemia	p.F1212C (No)	GDSC	Sunitinib	3.5803
SIDM00580	LAML\|acute_myeloid_leukaemia	p.F1212C (No)	GDSC	Sorafenib	14.1514
SIDM00580	LAML\|acute_myeloid_leukaemia	p.F1212C (No)	GDSC	Ponatinib	1.2453
SIDM00580	LAML\|acute_myeloid_leukaemia	p.F1212C (No)	GDSC	Cabozantinib	3.5647
SIDM00580	LAML\|acute_myeloid_leukaemia	p.F1212C (No)	GDSC	Linifanib	1.0581
SIDM00580	LAML\|acute_myeloid_leukaemia	p.F1212C (No)	GDSC	Foretinib	0.3025
SIDM00580	LAML\|acute_myeloid_leukaemia	p.F1212C (No)	GDSC	Tivozanib	1.8749
SIDM00580	LAML\|acute_myeloid_leukaemia	p.F1212C (No)	GDSC	Brivanib, BMS-540215	38.1602
SIDM00580	LAML\|acute_myeloid_leukaemia	p.F1212C (No)	GDSC	BIBF-1120	14.3756
SIDM00580	LAML\|acute_myeloid_leukaemia	p.F1212C (No)	GDSC	Axitinib	4.2422
SIDM00580	LAML\|acute_myeloid_leukaemia	p.F1212C (No)	GDSC	Motesanib	40.399
SIDM00580	LAML\|acute_myeloid_leukaemia	p.F1212C (No)	GDSC	Sorafenib	8.8965
SIDM00580	LAML\|acute_myeloid_leukaemia	p.F1212C (No)	GDSC	Cediranib	5.7332
SIDM00580	LAML\|acute_myeloid_leukaemia	p.F1212C (No)	GDSC	Foretinib	1.5694
SIDM00306	UNCLASSIFIED\|lung_NSCLC_large_cell	p.T1339I (No)	GDSC	Sunitinib	15.0793
SIDM00306	UNCLASSIFIED\|lung_NSCLC_large_cell	p.T1339I (No)	GDSC	Ponatinib	1.0928
SIDM00306	UNCLASSIFIED\|lung_NSCLC_large_cell	p.T1339I (No)	GDSC	Cabozantinib	53.0498
SIDM00306	UNCLASSIFIED\|lung_NSCLC_large_cell	p.T1339I (No)	GDSC	Linifanib	16.1099
SIDM00306	UNCLASSIFIED\|lung_NSCLC_large_cell	p.T1339I (No)	GDSC	Foretinib	4.2194
SIDM00306	UNCLASSIFIED\|lung_NSCLC_large_cell	p.T1339I (No)	GDSC	Tivozanib	1.9725
SIDM00306	UNCLASSIFIED\|lung_NSCLC_large_cell	p.T1339I (No)	GDSC	Brivanib, BMS-540215	79.1743
SIDM00306	UNCLASSIFIED\|lung_NSCLC_large_cell	p.T1339I (No)	GDSC	BIBF-1120	15.5854
SIDM00306	UNCLASSIFIED\|lung_NSCLC_large_cell	p.T1339I (No)	GDSC	Axitinib	10.1635
SIDM00306	UNCLASSIFIED\|lung_NSCLC_large_cell	p.T1339I (No)	GDSC	Motesanib	23.4403
SIDM00306	UNCLASSIFIED\|lung_NSCLC_large_cell	p.T1339I (No)	GDSC	Sorafenib	14.032
SIDM00306	UNCLASSIFIED\|lung_NSCLC_large_cell	p.T1339I (No)	GDSC	Cediranib	26.777
SIDM00306	UNCLASSIFIED\|lung_NSCLC_large_cell	p.T1339I (No)	GDSC	Foretinib	13.168
SIDM00490	GBM\|glioma	p.V1041L (No)	GDSC	Sunitinib	126.1618
SIDM00490	GBM\|glioma	p.V1041L (No)	GDSC	Sorafenib	7.3666
SIDM00490	GBM\|glioma	p.V1041L (No)	GDSC	Ponatinib	1.0396
SIDM00490	GBM\|glioma	p.V1041L (No)	GDSC	Cabozantinib	5.6926
SIDM00490	GBM\|glioma	p.V1041L (No)	GDSC	Linifanib	7.1256
SIDM00490	GBM\|glioma	p.V1041L (No)	GDSC	Foretinib	1.0657
SIDM00490	GBM\|glioma	p.V1041L (No)	GDSC	Tivozanib	1.5312
SIDM00490	GBM\|glioma	p.V1041L (No)	GDSC	Brivanib, BMS-540215	59.0675
SIDM00490	GBM\|glioma	p.V1041L (No)	GDSC	BIBF-1120	108.8012
SIDM00490	GBM\|glioma	p.V1041L (No)	GDSC	Axitinib	5.6293
SIDM00490	GBM\|glioma	p.V1041L (No)	GDSC	Motesanib	27.0296
SIDM00490	GBM\|glioma	p.V1041L (No)	GDSC	Sorafenib	29.602
SIDM00490	GBM\|glioma	p.V1041L (No)	GDSC	Cediranib	9.6316
SIDM00490	GBM\|glioma	p.V1041L (No)	GDSC	Foretinib	1.6438
SIDM00611	KIRC\|kidney	p.S1037L (No)	GDSC	Ponatinib	8.3321
SIDM00611	KIRC\|kidney	p.S1037L (No)	GDSC	Cabozantinib	30.1187
SIDM00611	KIRC\|kidney	p.S1037L (No)	GDSC	Linifanib	11.7738
SIDM00611	KIRC\|kidney	p.S1037L (No)	GDSC	Foretinib	1.5715
SIDM00611	KIRC\|kidney	p.S1037L (No)	GDSC	Tivozanib	2.1142
SIDM00611	KIRC\|kidney	p.S1037L (No)	GDSC	Brivanib, BMS-540215	42.1606
SIDM00611	KIRC\|kidney	p.S1037L (No)	GDSC	BIBF-1120	10.8231
SIDM00611	KIRC\|kidney	p.S1037L (No)	GDSC	Axitinib	9.3735
SIDM00611	KIRC\|kidney	p.S1037L (No)	GDSC	Motesanib	32.8628
SIDM00611	KIRC\|kidney	p.S1037L (No)	GDSC	Sorafenib	76.851
SIDM00611	KIRC\|kidney	p.S1037L (No)	GDSC	Cediranib	2.4313
SIDM00611	KIRC\|kidney	p.S1037L (No)	GDSC	Foretinib	11.908
SIDM01259	ALL\|lymphoblastic_leukemia	p.V1177L (No)	GDSC	Sunitinib	15.4202
SIDM01259	ALL\|lymphoblastic_leukemia	p.V1177L (No)	GDSC	Sorafenib	57.7181
SIDM01259	ALL\|lymphoblastic_leukemia	p.V1177L (No)	GDSC	Ponatinib	1.9397
SIDM01259	ALL\|lymphoblastic_leukemia	p.V1177L (No)	GDSC	Cabozantinib	19.1626
SIDM01259	ALL\|lymphoblastic_leukemia	p.V1177L (No)	GDSC	Linifanib	20.6562
SIDM01259	ALL\|lymphoblastic_leukemia	p.V1177L (No)	GDSC	Foretinib	0.5741
SIDM01259	ALL\|lymphoblastic_leukemia	p.V1177L (No)	GDSC	Tivozanib	2.1578
SIDM01259	ALL\|lymphoblastic_leukemia	p.V1177L (No)	GDSC	Brivanib, BMS-540215	28.3853
SIDM01259	ALL\|lymphoblastic_leukemia	p.V1177L (No)	GDSC	BIBF-1120	25.5856
SIDM01259	ALL\|lymphoblastic_leukemia	p.V1177L (No)	GDSC	Axitinib	4.0786
SIDM01259	ALL\|lymphoblastic_leukemia	p.V1177L (No)	GDSC	Motesanib	40.0823
SIDM01259	ALL\|lymphoblastic_leukemia	p.V1177L (No)	GDSC	Sorafenib	7.1912
SIDM01259	ALL\|lymphoblastic_leukemia	p.V1177L (No)	GDSC	Cediranib	2.0788
SIDM01259	ALL\|lymphoblastic_leukemia	p.V1177L (No)	GDSC	Foretinib	1.8666
SIDM01259	ALL\|lymphoblastic_leukemia	p.G174V (No)	GDSC	Sunitinib	15.4202
SIDM01259	ALL\|lymphoblastic_leukemia	p.G174V (No)	GDSC	Sorafenib	57.7181
SIDM01259	ALL\|lymphoblastic_leukemia	p.G174V (No)	GDSC	Ponatinib	1.9397
SIDM01259	ALL\|lymphoblastic_leukemia	p.G174V (No)	GDSC	Cabozantinib	19.1626
SIDM01259	ALL\|lymphoblastic_leukemia	p.G174V (No)	GDSC	Linifanib	20.6562
SIDM01259	ALL\|lymphoblastic_leukemia	p.G174V (No)	GDSC	Foretinib	0.5741
SIDM01259	ALL\|lymphoblastic_leukemia	p.G174V (No)	GDSC	Tivozanib	2.1578
SIDM01259	ALL\|lymphoblastic_leukemia	p.G174V (No)	GDSC	Brivanib, BMS-540215	28.3853
SIDM01259	ALL\|lymphoblastic_leukemia	p.G174V (No)	GDSC	BIBF-1120	25.5856
SIDM01259	ALL\|lymphoblastic_leukemia	p.G174V (No)	GDSC	Axitinib	4.0786
SIDM01259	ALL\|lymphoblastic_leukemia	p.G174V (No)	GDSC	Motesanib	40.0823
SIDM01259	ALL\|lymphoblastic_leukemia	p.G174V (No)	GDSC	Sorafenib	7.1912
SIDM01259	ALL\|lymphoblastic_leukemia	p.G174V (No)	GDSC	Cediranib	2.0788
SIDM01259	ALL\|lymphoblastic_leukemia	p.G174V (No)	GDSC	Foretinib	1.8666
SIDM00537	COREAD\|large_intestine	p.L415V (No)	GDSC	Ponatinib	1.9526
SIDM00537	COREAD\|large_intestine	p.L415V (No)	GDSC	Cabozantinib	8.3183
SIDM00537	COREAD\|large_intestine	p.L415V (No)	GDSC	Linifanib	0.9776
SIDM00537	COREAD\|large_intestine	p.L415V (No)	GDSC	Foretinib	1.1726
SIDM00537	COREAD\|large_intestine	p.L415V (No)	GDSC	Tivozanib	1.2326
SIDM00537	COREAD\|large_intestine	p.L415V (No)	GDSC	Brivanib, BMS-540215	108.0195
SIDM00537	COREAD\|large_intestine	p.L415V (No)	GDSC	BIBF-1120	12.4791
SIDM00537	COREAD\|large_intestine	p.L415V (No)	GDSC	Axitinib	4.497
SIDM00537	COREAD\|large_intestine	p.L415V (No)	GDSC	Motesanib	9.6673
SIDM00537	COREAD\|large_intestine	p.L415V (No)	GDSC	Sorafenib	6.3081
SIDM00537	COREAD\|large_intestine	p.L415V (No)	GDSC	Cediranib	6.2083
SIDM00537	COREAD\|large_intestine	p.L415V (No)	GDSC	Foretinib	1.3073
SIDM00374	DLBC\|B_cell_lymphoma	p.P64L (No)	GDSC	Sunitinib	11.0351
SIDM00374	DLBC\|B_cell_lymphoma	p.P64L (No)	GDSC	Sorafenib	8.4394
SIDM00374	DLBC\|B_cell_lymphoma	p.P64L (No)	GDSC	Ponatinib	0.6336
SIDM00374	DLBC\|B_cell_lymphoma	p.P64L (No)	GDSC	Cabozantinib	9.9816
SIDM00374	DLBC\|B_cell_lymphoma	p.P64L (No)	GDSC	Linifanib	0.289
SIDM00374	DLBC\|B_cell_lymphoma	p.P64L (No)	GDSC	Foretinib	0.5928
SIDM00374	DLBC\|B_cell_lymphoma	p.P64L (No)	GDSC	Tivozanib	0.9947
SIDM00374	DLBC\|B_cell_lymphoma	p.P64L (No)	GDSC	Brivanib, BMS-540215	94.7947
SIDM00374	DLBC\|B_cell_lymphoma	p.P64L (No)	GDSC	BIBF-1120	49.7188
SIDM00374	DLBC\|B_cell_lymphoma	p.P64L (No)	GDSC	Axitinib	20.0647
SIDM00374	DLBC\|B_cell_lymphoma	p.P64L (No)	GDSC	Motesanib	27.4647
SIDM00374	DLBC\|B_cell_lymphoma	p.P64L (No)	GDSC	Sorafenib	4.9857
SIDM00374	DLBC\|B_cell_lymphoma	p.P64L (No)	GDSC	Cediranib	12.852
SIDM00374	DLBC\|B_cell_lymphoma	p.P64L (No)	GDSC	Foretinib	2.043
SIDM00653	SCLC\|lung_small_cell_carcinoma	p.D392N (No)	GDSC	Sunitinib	67.5213
SIDM00653	SCLC\|lung_small_cell_carcinoma	p.D392N (No)	GDSC	Sorafenib	73.9548
SIDM00653	SCLC\|lung_small_cell_carcinoma	p.D392N (No)	GDSC	Ponatinib	11.0034
SIDM00653	SCLC\|lung_small_cell_carcinoma	p.D392N (No)	GDSC	Cabozantinib	41.8362
SIDM00653	SCLC\|lung_small_cell_carcinoma	p.D392N (No)	GDSC	Linifanib	14.5522
SIDM00653	SCLC\|lung_small_cell_carcinoma	p.D392N (No)	GDSC	Foretinib	1.9663
SIDM00653	SCLC\|lung_small_cell_carcinoma	p.D392N (No)	GDSC	Tivozanib	1.7912
SIDM00653	SCLC\|lung_small_cell_carcinoma	p.D392N (No)	GDSC	Brivanib, BMS-540215	91.5106
SIDM00653	SCLC\|lung_small_cell_carcinoma	p.D392N (No)	GDSC	BIBF-1120	28.9637
SIDM00653	SCLC\|lung_small_cell_carcinoma	p.D392N (No)	GDSC	Axitinib	37.3897
SIDM00653	SCLC\|lung_small_cell_carcinoma	p.D392N (No)	GDSC	Motesanib	15.5156
SIDM00653	SCLC\|lung_small_cell_carcinoma	p.D392N (No)	GDSC	Sorafenib	14.353
SIDM00653	SCLC\|lung_small_cell_carcinoma	p.D392N (No)	GDSC	Cediranib	50.947
SIDM00653	SCLC\|lung_small_cell_carcinoma	p.D392N (No)	GDSC	Foretinib	9.8277
SIDM00562	BRCA\|breast	p.G494E (No)	GDSC	Sunitinib	27.0556
SIDM00562	BRCA\|breast	p.G494E (No)	GDSC	Sorafenib	3.7949
SIDM00562	BRCA\|breast	p.G494E (No)	GDSC	Ponatinib	4.2843
SIDM00562	BRCA\|breast	p.G494E (No)	GDSC	Cabozantinib	31.0827
SIDM00562	BRCA\|breast	p.G494E (No)	GDSC	Linifanib	16.66
SIDM00562	BRCA\|breast	p.G494E (No)	GDSC	Foretinib	4.5059
SIDM00562	BRCA\|breast	p.G494E (No)	GDSC	Tivozanib	2.1452
SIDM00562	BRCA\|breast	p.G494E (No)	GDSC	Brivanib, BMS-540215	18.1438
SIDM00562	BRCA\|breast	p.G494E (No)	GDSC	BIBF-1120	6.7933
SIDM00562	BRCA\|breast	p.G494E (No)	GDSC	Axitinib	12.8183
SIDM00562	BRCA\|breast	p.G494E (No)	GDSC	Motesanib	33.3661
SIDM00562	BRCA\|breast	p.G494E (No)	GDSC	Axitinib	10.074
SIDM00562	BRCA\|breast	p.G494E (No)	GDSC	Sorafenib	3.3717
SIDM00562	BRCA\|breast	p.G494E (No)	GDSC	Cediranib	36.443
SIDM00562	BRCA\|breast	p.G494E (No)	GDSC	Foretinib	3.0689
SIDM00416	DLBC\|B_cell_lymphoma	p.K630T (No)	GDSC	Sorafenib	5.3544
SIDM00416	DLBC\|B_cell_lymphoma	p.K630T (No)	GDSC	Ponatinib	0.1539
SIDM00416	DLBC\|B_cell_lymphoma	p.K630T (No)	GDSC	Cabozantinib	7.319
SIDM00416	DLBC\|B_cell_lymphoma	p.K630T (No)	GDSC	Linifanib	15.6177
SIDM00416	DLBC\|B_cell_lymphoma	p.K630T (No)	GDSC	Foretinib	0.3701
SIDM00416	DLBC\|B_cell_lymphoma	p.K630T (No)	GDSC	Tivozanib	1.0384
SIDM00416	DLBC\|B_cell_lymphoma	p.K630T (No)	GDSC	Brivanib, BMS-540215	7.9866
SIDM00416	DLBC\|B_cell_lymphoma	p.K630T (No)	GDSC	BIBF-1120	5.1981
SIDM00416	DLBC\|B_cell_lymphoma	p.K630T (No)	GDSC	Axitinib	6.6141
SIDM00416	DLBC\|B_cell_lymphoma	p.K630T (No)	GDSC	Motesanib	30.7019
SIDM00416	DLBC\|B_cell_lymphoma	p.K630T (No)	GDSC	Sorafenib	6.4979
SIDM00416	DLBC\|B_cell_lymphoma	p.K630T (No)	GDSC	Cediranib	4.6927
SIDM00416	DLBC\|B_cell_lymphoma	p.K630T (No)	GDSC	Foretinib	0.704
SIDM01219	UNCLASSIFIED\|lung_NSCLC_large_cell	p.R791Q (No)	GDSC	Ponatinib	0.6427
SIDM01219	UNCLASSIFIED\|lung_NSCLC_large_cell	p.R791Q (No)	GDSC	Cabozantinib	24.5766
SIDM01219	UNCLASSIFIED\|lung_NSCLC_large_cell	p.R791Q (No)	GDSC	Linifanib	11.3834
SIDM01219	UNCLASSIFIED\|lung_NSCLC_large_cell	p.R791Q (No)	GDSC	Foretinib	0.9473
SIDM01219	UNCLASSIFIED\|lung_NSCLC_large_cell	p.R791Q (No)	GDSC	Tivozanib	1.8289
SIDM01219	UNCLASSIFIED\|lung_NSCLC_large_cell	p.R791Q (No)	GDSC	Brivanib, BMS-540215	52.9136
SIDM01219	UNCLASSIFIED\|lung_NSCLC_large_cell	p.R791Q (No)	GDSC	BIBF-1120	35.941
SIDM01219	UNCLASSIFIED\|lung_NSCLC_large_cell	p.R791Q (No)	GDSC	Axitinib	27.0347
SIDM01219	UNCLASSIFIED\|lung_NSCLC_large_cell	p.R791Q (No)	GDSC	Motesanib	2.6626
SIDM01219	UNCLASSIFIED\|lung_NSCLC_large_cell	p.R791Q (No)	GDSC	Sorafenib	22.114
SIDM01219	UNCLASSIFIED\|lung_NSCLC_large_cell	p.R791Q (No)	GDSC	Cediranib	11.978
SIDM01219	UNCLASSIFIED\|lung_NSCLC_large_cell	p.R791Q (No)	GDSC	Foretinib	3.9586
SIDM01219	UNCLASSIFIED\|lung_NSCLC_large_cell	p.G255R (No)	GDSC	Ponatinib	0.6427
SIDM01219	UNCLASSIFIED\|lung_NSCLC_large_cell	p.G255R (No)	GDSC	Cabozantinib	24.5766
SIDM01219	UNCLASSIFIED\|lung_NSCLC_large_cell	p.G255R (No)	GDSC	Linifanib	11.3834
SIDM01219	UNCLASSIFIED\|lung_NSCLC_large_cell	p.G255R (No)	GDSC	Foretinib	0.9473
SIDM01219	UNCLASSIFIED\|lung_NSCLC_large_cell	p.G255R (No)	GDSC	Tivozanib	1.8289
SIDM01219	UNCLASSIFIED\|lung_NSCLC_large_cell	p.G255R (No)	GDSC	Brivanib, BMS-540215	52.9136
SIDM01219	UNCLASSIFIED\|lung_NSCLC_large_cell	p.G255R (No)	GDSC	BIBF-1120	35.941
SIDM01219	UNCLASSIFIED\|lung_NSCLC_large_cell	p.G255R (No)	GDSC	Axitinib	27.0347
SIDM01219	UNCLASSIFIED\|lung_NSCLC_large_cell	p.G255R (No)	GDSC	Motesanib	2.6626
SIDM01219	UNCLASSIFIED\|lung_NSCLC_large_cell	p.G255R (No)	GDSC	Sorafenib	22.114
SIDM01219	UNCLASSIFIED\|lung_NSCLC_large_cell	p.G255R (No)	GDSC	Cediranib	11.978
SIDM01219	UNCLASSIFIED\|lung_NSCLC_large_cell	p.G255R (No)	GDSC	Foretinib	3.9586
SIDM00193	COREAD\|large_intestine	p.R1232Q (No)	GDSC	Cabozantinib	133.9123
SIDM00193	COREAD\|large_intestine	p.R1232Q (No)	GDSC	Linifanib	15.5526
SIDM00193	COREAD\|large_intestine	p.R1232Q (No)	GDSC	Foretinib	7.8838
SIDM00193	COREAD\|large_intestine	p.R1232Q (No)	GDSC	Tivozanib	1.8904
SIDM00193	COREAD\|large_intestine	p.R1232Q (No)	GDSC	Brivanib, BMS-540215	511.1612
SIDM00193	COREAD\|large_intestine	p.R1232Q (No)	GDSC	BIBF-1120	524.2554
SIDM00193	COREAD\|large_intestine	p.R1232Q (No)	GDSC	Axitinib	12.6981
SIDM00193	COREAD\|large_intestine	p.R1232Q (No)	GDSC	Motesanib	50.1977
SIDM00193	COREAD\|large_intestine	p.E705D (No)	GDSC	Cabozantinib	133.9123
SIDM00193	COREAD\|large_intestine	p.E705D (No)	GDSC	Linifanib	15.5526
SIDM00193	COREAD\|large_intestine	p.E705D (No)	GDSC	Foretinib	7.8838
SIDM00193	COREAD\|large_intestine	p.E705D (No)	GDSC	Tivozanib	1.8904
SIDM00193	COREAD\|large_intestine	p.E705D (No)	GDSC	Brivanib, BMS-540215	511.1612
SIDM00193	COREAD\|large_intestine	p.E705D (No)	GDSC	BIBF-1120	524.2554
SIDM00193	COREAD\|large_intestine	p.E705D (No)	GDSC	Axitinib	12.6981
SIDM00193	COREAD\|large_intestine	p.E705D (No)	GDSC	Motesanib	50.1977
SIDM00118	COREAD\|large_intestine	p.Q37H (No)	GDSC	Sorafenib	2.2419
SIDM00118	COREAD\|large_intestine	p.Q37H (No)	GDSC	Ponatinib	6.496
SIDM00118	COREAD\|large_intestine	p.Q37H (No)	GDSC	Cabozantinib	28.7329
SIDM00118	COREAD\|large_intestine	p.Q37H (No)	GDSC	Linifanib	12.9878
SIDM00118	COREAD\|large_intestine	p.Q37H (No)	GDSC	Foretinib	3.6532
SIDM00118	COREAD\|large_intestine	p.Q37H (No)	GDSC	Tivozanib	1.6445
SIDM00118	COREAD\|large_intestine	p.Q37H (No)	GDSC	Brivanib, BMS-540215	110.6657
SIDM00118	COREAD\|large_intestine	p.Q37H (No)	GDSC	BIBF-1120	53.3315
SIDM00118	COREAD\|large_intestine	p.Q37H (No)	GDSC	Axitinib	18.812
SIDM00118	COREAD\|large_intestine	p.Q37H (No)	GDSC	Motesanib	6.3211
SIDM00118	COREAD\|large_intestine	p.Q37H (No)	GDSC	Sorafenib	7.5049
SIDM00118	COREAD\|large_intestine	p.Q37H (No)	GDSC	Cediranib	5.8015
SIDM00118	COREAD\|large_intestine	p.Q37H (No)	GDSC	Foretinib	4.088
SIDM00086	KIRC\|kidney	p.L625S (No)	GDSC	Sunitinib	6.1015
SIDM00086	KIRC\|kidney	p.L625S (No)	GDSC	Sorafenib	47.6718
SIDM00086	KIRC\|kidney	p.L625S (No)	GDSC	Ponatinib	4.5028
SIDM00086	KIRC\|kidney	p.L625S (No)	GDSC	Cabozantinib	6.1357
SIDM00086	KIRC\|kidney	p.L625S (No)	GDSC	Linifanib	17.0511
SIDM00086	KIRC\|kidney	p.L625S (No)	GDSC	Foretinib	0.4155
SIDM00086	KIRC\|kidney	p.L625S (No)	GDSC	Tivozanib	3.0378
SIDM00086	KIRC\|kidney	p.L625S (No)	GDSC	Brivanib, BMS-540215	284.6675
SIDM00086	KIRC\|kidney	p.L625S (No)	GDSC	BIBF-1120	20.1618
SIDM00086	KIRC\|kidney	p.L625S (No)	GDSC	Axitinib	10.2451
SIDM00086	KIRC\|kidney	p.L625S (No)	GDSC	Motesanib	19.4607

All proteins holding degron of DYR

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
O00139	Kinesin-like protein KIF2A	CBL_MET	209:211	DYR	CBL	0.9462	More...
O00571	ATP-dependent RNA helicase DDX3X	CBL_MET	601:603	DYR	CBL	0.9982	More...
O00629	Importin subunit alpha-3	CBL_MET	65:67	DYR	CBL	0.7682	More...
O14646	Chromodomain-helicase-DNA-binding protein 1	CBL_MET	1657:1659	DYR	CBL	0.9833	More...
O15020	Spectrin beta chain, non-erythrocytic 2	CBL_MET	2288:2290	DYR	CBL	0.6427	More...
O15047	Histone-lysine N-methyltransferase SETD1A	CBL_MET	424:426	DYR	CBL	0.8226	More...
O15523	ATP-dependent RNA helicase DDX3Y	CBL_MET	599:601	DYR	CBL	0.9998	More...
O15553	Pyrin	CBL_MET	723:725	DYR	CBL	0.8162	More...
O43676	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3	CBL_MET	18:20	DYR	CBL	0.9451	More...
O60264	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5	CBL_MET	140:142	DYR	CBL	0.9955	More...
O60264	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5	CBL_MET	718:720	DYR	CBL	0.8031	More...
O75334	Liprin-alpha-2	CBL_MET	568:570	DYR	CBL	0.5843	More...
O75376	Nuclear receptor corepressor 1	CBL_MET	42:44	DYR	CBL	0.7623	More...
O75420	GRB10-interacting GYF protein 1	CBL_MET	38:40	DYR	CBL	0.6199	More...
O75879	Glutamyl-tRNA	CBL_MET	334:336	DYR	CBL	0.9961	More...
O75925	E3 SUMO-protein ligase PIAS1	CBL_MET	526:528	DYR	CBL	0.814	More...
O95271	Poly [ADP-ribose] polymerase tankyrase-1	CBL_MET	651:653	DYR	CBL	0.5061	More...
O95359	Transforming acidic coiled-coil-containing protein 2	CBL_MET	2518:2520	DYR	CBL	0.9518	More...
O95948	One cut domain family member 2	CBL_MET	118:120	DYR	CBL	0.8889	More...
P00736	Complement C1r subcomponent	CBL_MET	545:547	DYR	CBL	0.6636	More...
P04264	Keratin, type II cytoskeletal 1	CBL_MET	265:267	DYR	CBL	0.8471	More...
P08581	Hepatocyte growth factor receptor	CBL_MET	1002:1004	DYR	CBL	0.9838	More...
P0C1Z6	TCF3 fusion partner	CBL_MET	130:132	DYR	CBL	0.6994	More...
P10515	Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial	CBL_MET	305:307	DYR	CBL	0.8796	More...
P13942	Collagen alpha-2	CBL_MET	353:355	DYR	CBL	0.5731	More...
P20810	Calpastatin	CBL_MET	480:482	DYR	CBL	0.9683	More...
P23588	Eukaryotic translation initiation factor 4B	CBL_MET	290:292	DYR	CBL	0.9781	More...
P24666	Low molecular weight phosphotyrosine protein phosphatase	CBL_MET	57:59	DYR	CBL	0.5377	More...
P25440	Bromodomain-containing protein 2	CBL_MET	407:409	DYR	CBL	0.9586	More...
P26842	CD27 antigen	CBL_MET	250:252	DYR	CBL	0.6901	More...
P28370	Probable global transcription activator SNF2L1	CBL_MET	143:145	DYR	CBL	0.74	More...
P30305	M-phase inducer phosphatase 2	CBL_MET	541:543	DYR	CBL	0.9803	More...
P35968	Vascular endothelial growth factor receptor 2	CBL_MET	120:122	DYR	CBL	0.5317	More...
P40145	Adenylate cyclase type 8	CBL_MET	1148:1150	DYR	CBL	0.7268	More...
P40424	Pre-B-cell leukemia transcription factor 1	CBL_MET	149:151	DYR	CBL	0.8542	More...
P40425	Pre-B-cell leukemia transcription factor 2	CBL_MET	160:162	DYR	CBL	0.8868	More...
P41587	Vasoactive intestinal polypeptide receptor 2	CBL_MET	402:404	DYR	CBL	0.6233	More...
P49736	DNA replication licensing factor MCM2	CBL_MET	80:82	DYR	CBL	0.9704	More...
P49760	Dual specificity protein kinase CLK2	CBL_MET	94:96	DYR	CBL	0.9942	More...
P51805	Plexin-A3	CBL_MET	1298:1300	DYR	CBL	0.9239	More...
P51825	AF4/FMR2 family member 1	CBL_MET	316:318	DYR	CBL	0.9069	More...
P51854	Transketolase-like protein 1	CBL_MET	282:284	DYR	CBL	0.9474	More...
P52756	RNA-binding protein 5	CBL_MET	53:55	DYR	CBL	0.9985	More...
P52756	RNA-binding protein 5	CBL_MET	86:88	DYR	CBL	0.9953	More...
P54760	Ephrin type-B receptor 4	CBL_MET	836:838	DYR	CBL	0.633	More...
P54762	Ephrin type-B receptor 1	CBL_MET	840:842	DYR	CBL	0.7094	More...
P56715	Oxygen-regulated protein 1	CBL_MET	1593:1595	DYR	CBL	0.9936	More...
P62333	26S proteasome regulatory subunit 10B	CBL_MET	11:13	DYR	CBL	0.5589	More...
P78332	RNA-binding protein 6	CBL_MET	84:86	DYR	CBL	0.8516	More...
P78332	RNA-binding protein 6	CBL_MET	134:136	DYR	CBL	0.9878	More...
P78332	RNA-binding protein 6	CBL_MET	144:146	DYR	CBL	0.9933	More...
P78332	RNA-binding protein 6	CBL_MET	400:402	DYR	CBL	0.994	More...
P78332	RNA-binding protein 6	CBL_MET	444:446	DYR	CBL	0.9571	More...
P78559	Microtubule-associated protein 1A	CBL_MET	1908:1910	DYR	CBL	0.7957	More...
P84103	Serine/arginine-rich splicing factor 3	CBL_MET	103:105	DYR	CBL	0.9202	More...
P98175	RNA-binding protein 10	CBL_MET	35:37	DYR	CBL	0.8937	More...
P98175	RNA-binding protein 10	CBL_MET	40:42	DYR	CBL	0.9885	More...
P98175	RNA-binding protein 10	CBL_MET	101:103	DYR	CBL	0.9929	More...
P98175	RNA-binding protein 10	CBL_MET	106:108	DYR	CBL	0.9935	More...
Q01668	Voltage-dependent L-type calcium channel subunit alpha-1D	CBL_MET	807:809	DYR	CBL	0.9538	More...
Q01804	OTU domain-containing protein 4	CBL_MET	360:362	DYR	CBL	0.9712	More...
Q01973	Inactive tyrosine-protein kinase transmembrane receptor ROR1	CBL_MET	320:322	DYR	CBL	0.9644	More...
Q04912	Macrophage-stimulating protein receptor	CBL_MET	292:294	DYR	CBL	0.9076	More...
Q04912	Macrophage-stimulating protein receptor	CBL_MET	1016:1018	DYR	CBL	0.9418	More...
Q07954	Prolow-density lipoprotein receptor-related protein 1	CBL_MET	2242:2244	DYR	CBL	0.5092	More...
Q08211	ATP-dependent RNA helicase A	CBL_MET	1233:1235	DYR	CBL	0.9757	More...
Q08378	Golgin subfamily A member 3	CBL_MET	248:250	DYR	CBL	0.9928	More...
Q08380	Galectin-3-binding protein	CBL_MET	452:454	DYR	CBL	0.7593	More...
Q12802	A-kinase anchor protein 13	CBL_MET	823:825	DYR	CBL	0.8159	More...
Q13595	Transformer-2 protein homolog alpha	CBL_MET	253:255	DYR	CBL	0.53	More...
Q13796	Protein Shroom2	CBL_MET	1018:1020	DYR	CBL	0.987	More...
Q14004	Cyclin-dependent kinase 13	CBL_MET	1276:1278	DYR	CBL	0.9353	More...
Q14247	Src substrate cortactin	CBL_MET	452:454	DYR	CBL	0.9377	More...
Q14257	Reticulocalbin-2	CBL_MET	214:216	DYR	CBL	0.5984	More...
Q14722	Voltage-gated potassium channel subunit beta-1	CBL_MET	416:418	DYR	CBL	0.9463	More...
Q14966	Zinc finger protein 638	CBL_MET	1482:1484	DYR	CBL	0.9903	More...
Q15003	Condensin complex subunit 2	CBL_MET	269:271	DYR	CBL	0.6611	More...
Q15464	SH2 domain-containing adapter protein B	CBL_MET	26:28	DYR	CBL	0.5914	More...
Q15746	Myosin light chain kinase, smooth muscle	CBL_MET	1448:1450	DYR	CBL	0.6844	More...
Q16625	Occludin	CBL_MET	466:468	DYR	CBL	0.9972	More...
Q2LD37	Transmembrane protein KIAA1109	CBL_MET	3517:3519	DYR	CBL	0.7981	More...
Q2TAL6	Brorin	CBL_MET	149:151	DYR	CBL	0.987	More...
Q5T011	KICSTOR complex protein SZT2	CBL_MET	759:761	DYR	CBL	0.8358	More...
Q5T200	Zinc finger CCCH domain-containing protein 13	CBL_MET	506:508	DYR	CBL	0.9991	More...
Q5T5U3	Rho GTPase-activating protein 21	CBL_MET	888:890	DYR	CBL	0.9971	More...
Q5VT52	Regulation of nuclear pre-mRNA domain-containing protein 2	CBL_MET	832:834	DYR	CBL	0.992	More...
Q5VUA4	Zinc finger protein 318	CBL_MET	223:225	DYR	CBL	0.5829	More...
Q5VUB5	Protein FAM171A1	CBL_MET	484:486	DYR	CBL	0.9956	More...
Q5VV43	Dyslexia-associated protein KIAA0319	CBL_MET	159:161	DYR	CBL	0.8877	More...
Q6IQ20	N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D	CBL_MET	47:49	DYR	CBL	0.988	More...
Q6IS24	Polypeptide N-acetylgalactosaminyltransferase 17	CBL_MET	136:138	DYR	CBL	0.6035	More...
Q6UB99	Ankyrin repeat domain-containing protein 11	CBL_MET	864:866	DYR	CBL	0.5334	More...
Q6UB99	Ankyrin repeat domain-containing protein 11	CBL_MET	899:901	DYR	CBL	0.7809	More...
Q6ZS17	Rho family-interacting cell polarization regulator 1	CBL_MET	807:809	DYR	CBL	0.861	More...
Q7Z2W4	Zinc finger CCCH-type antiviral protein 1	CBL_MET	409:411	DYR	CBL	0.5401	More...
Q7Z4T9	Cilia- and flagella-associated protein 91	CBL_MET	194:196	DYR	CBL	0.6194	More...
Q7Z698	Sprouty-related, EVH1 domain-containing protein 2	CBL_MET	230:232	DYR	CBL	0.9995	More...
Q7Z699	Sprouty-related, EVH1 domain-containing protein 1	CBL_MET	260:262	DYR	CBL	0.8061	More...
Q86UL8	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2	CBL_MET	1113:1115	DYR	CBL	0.5682	More...
Q86UW6	NEDD4-binding protein 2	CBL_MET	1621:1623	DYR	CBL	0.9143	More...
Q86WI1	Fibrocystin-L	CBL_MET	3717:3719	DYR	CBL	0.5999	More...
Q86YV5	Inactive tyrosine-protein kinase PRAG1	CBL_MET	1281:1283	DYR	CBL	0.8047	More...
Q8IV36	Protein HID1	CBL_MET	275:277	DYR	CBL	0.7188	More...
Q8IXQ5	Kelch-like protein 7	CBL_MET	292:294	DYR	CBL	0.6031	More...
Q8IYB7	DIS3-like exonuclease 2	CBL_MET	5:7	DYR	CBL	0.7018	More...
Q8NDX1	PH and SEC7 domain-containing protein 4	CBL_MET	4:6	DYR	CBL	0.9301	More...
Q8NEY8	Periphilin-1	CBL_MET	57:59	DYR	CBL	0.9982	More...
Q8NFW5	Diencephalon/mesencephalon homeobox protein 1	CBL_MET	36:38	DYR	CBL	0.9784	More...
Q8TCS8	Polyribonucleotide nucleotidyltransferase 1, mitochondrial	CBL_MET	101:103	DYR	CBL	0.6954	More...
Q8TDC0	Myozenin-3	CBL_MET	190:192	DYR	CBL	0.7683	More...
Q8TDJ6	DmX-like protein 2	CBL_MET	2716:2718	DYR	CBL	0.8574	More...
Q8TEB1	DDB1- and CUL4-associated factor 11	CBL_MET	406:408	DYR	CBL	0.9704	More...
Q8TF46	DIS3-like exonuclease 1	CBL_MET	371:373	DYR	CBL	0.9736	More...
Q8WVM8	Sec1 family domain-containing protein 1	CBL_MET	565:567	DYR	CBL	0.9885	More...
Q92620	Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16	CBL_MET	498:500	DYR	CBL	0.9106	More...
Q92804	TATA-binding protein-associated factor 2N	CBL_MET	582:584	DYR	CBL	0.8251	More...
Q92835	Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1	CBL_MET	1160:1162	DYR	CBL	0.9908	More...
Q92896	Golgi apparatus protein 1	CBL_MET	230:232	DYR	CBL	0.9413	More...
Q92896	Golgi apparatus protein 1	CBL_MET	931:933	DYR	CBL	0.8383	More...
Q96AH0	SOSS complex subunit B2	CBL_MET	118:120	DYR	CBL	0.6249	More...
Q96G01	Protein bicaudal D homolog 1	CBL_MET	299:301	DYR	CBL	0.9969	More...
Q96J84	Kin of IRRE-like protein 1	CBL_MET	624:626	DYR	CBL	0.925	More...
Q96JC1	Vam6/Vps39-like protein	CBL_MET	390:392	DYR	CBL	0.5993	More...
Q96JE7	Protein transport protein Sec16B	CBL_MET	150:152	DYR	CBL	0.7792	More...
Q96JE9	Microtubule-associated protein 6	CBL_MET	124:126	DYR	CBL	0.9892	More...
Q96K21	Abscission/NoCut checkpoint regulator	CBL_MET	348:350	DYR	CBL	0.5257	More...
Q96NW4	Ankyrin repeat domain-containing protein 27	CBL_MET	666:668	DYR	CBL	0.9069	More...
Q96PK6	RNA-binding protein 14	CBL_MET	613:615	DYR	CBL	0.9916	More...
Q96PK6	RNA-binding protein 14	CBL_MET	634:636	DYR	CBL	0.9946	More...
Q96S66	Chloride channel CLIC-like protein 1	CBL_MET	386:388	DYR	CBL	0.9205	More...
Q96T37	RNA-binding protein 15	CBL_MET	304:306	DYR	CBL	0.9655	More...
Q99595	Mitochondrial import inner membrane translocase subunit Tim17-A	CBL_MET	166:168	DYR	CBL	0.9893	More...
Q99795	Cell surface A33 antigen	CBL_MET	300:302	DYR	CBL	0.8146	More...
Q99932	Sperm-associated antigen 8	CBL_MET	385:387	DYR	CBL	0.5131	More...
Q9BQS8	FYVE and coiled-coil domain-containing protein 1	CBL_MET	1271:1273	DYR	CBL	0.5789	More...
Q9BSE2	Transmembrane protein 79	CBL_MET	387:389	DYR	CBL	0.6448	More...
Q9BTA9	WW domain-containing adapter protein with coiled-coil	CBL_MET	186:188	DYR	CBL	0.7509	More...
Q9BTA9	WW domain-containing adapter protein with coiled-coil	CBL_MET	231:233	DYR	CBL	0.7463	More...
Q9BZC7	ATP-binding cassette sub-family A member 2	CBL_MET	1395:1397	DYR	CBL	0.9909	More...
Q9BZJ0	Crooked neck-like protein 1	CBL_MET	272:274	DYR	CBL	0.6918	More...
Q9H078	Caseinolytic peptidase B protein homolog	CBL_MET	278:280	DYR	CBL	0.5353	More...
Q9H0G5	Nuclear speckle splicing regulatory protein 1	CBL_MET	336:338	DYR	CBL	0.6151	More...
Q9H116	GDNF-inducible zinc finger protein 1	CBL_MET	257:259	DYR	CBL	0.6224	More...
Q9H270	Vacuolar protein sorting-associated protein 11 homolog	CBL_MET	570:572	DYR	CBL	0.99	More...
Q9H7E9	UPF0488 protein C8orf33	CBL_MET	165:167	DYR	CBL	0.8994	More...
Q9HAD4	WD repeat-containing protein 41	CBL_MET	54:56	DYR	CBL	0.8451	More...
Q9HAU0	Pleckstrin homology domain-containing family A member 5	CBL_MET	803:805	DYR	CBL	0.9956	More...
Q9HAZ1	Dual specificity protein kinase CLK4	CBL_MET	66:68	DYR	CBL	0.8055	More...
Q9HCM1	Retroelement silencing factor 1	CBL_MET	210:212	DYR	CBL	0.9737	More...
Q9HCQ5	Polypeptide N-acetylgalactosaminyltransferase 9	CBL_MET	135:137	DYR	CBL	0.9537	More...
Q9HD67	Unconventional myosin-X	CBL_MET	1120:1122	DYR	CBL	0.6143	More...
Q9NQV6	PR domain zinc finger protein 10	CBL_MET	913:915	DYR	CBL	0.9044	More...
Q9NRA8	Eukaryotic translation initiation factor 4E transporter	CBL_MET	782:784	DYR	CBL	0.8248	More...
Q9NSI6	Bromodomain and WD repeat-containing protein 1	CBL_MET	563:565	DYR	CBL	0.9622	More...
Q9NVM9	Integrator complex subunit 13	CBL_MET	412:414	DYR	CBL	0.9056	More...
Q9NWK9	Box C/D snoRNA protein 1	CBL_MET	277:279	DYR	CBL	0.8233	More...
Q9NYF0	Dapper homolog 1	CBL_MET	675:677	DYR	CBL	0.996	More...
Q9NYF8	Bcl-2-associated transcription factor 1	CBL_MET	56:58	DYR	CBL	0.7315	More...
Q9NYF8	Bcl-2-associated transcription factor 1	CBL_MET	60:62	DYR	CBL	0.9219	More...
Q9NYF8	Bcl-2-associated transcription factor 1	CBL_MET	407:409	DYR	CBL	0.8675	More...
Q9NZP8	Complement C1r subcomponent-like protein	CBL_MET	327:329	DYR	CBL	0.7258	More...
Q9P0K7	Ankycorbin	CBL_MET	661:663	DYR	CBL	0.6245	More...
Q9P1A6	Disks large-associated protein 2	CBL_MET	831:833	DYR	CBL	0.927	More...
Q9P2B4	CTTNBP2 N-terminal-like protein	CBL_MET	532:534	DYR	CBL	0.9696	More...
Q9P2N4	A disintegrin and metalloproteinase with thrombospondin motifs 9	CBL_MET	1313:1315	DYR	CBL	0.9337	More...
Q9UER7	Death domain-associated protein 6	CBL_MET	343:345	DYR	CBL	0.6964	More...
Q9UEW8	STE20/SPS1-related proline-alanine-rich protein kinase	CBL_MET	443:445	DYR	CBL	0.6777	More...
Q9UIW2	Plexin-A1	CBL_MET	441:443	DYR	CBL	0.9623	More...
Q9UIW2	Plexin-A1	CBL_MET	1323:1325	DYR	CBL	0.8813	More...
Q9UJM3	ERBB receptor feedback inhibitor 1	CBL_MET	297:299	DYR	CBL	0.9805	More...
Q9ULE0	Protein WWC3	CBL_MET	1035:1037	DYR	CBL	0.5665	More...
Q9UPN3	Microtubule-actin cross-linking factor 1, isoforms 1/2/3/4/5	CBL_MET	878:880	DYR	CBL	0.7589	More...
Q9UPR5	Sodium/calcium exchanger 2	CBL_MET	430:432	DYR	CBL	0.624	More...
Q9UQ26	Regulating synaptic membrane exocytosis protein 2	CBL_MET	986:988	DYR	CBL	0.5284	More...
Q9UQQ2	SH2B adapter protein 3	CBL_MET	88:90	DYR	CBL	0.9861	More...
Q9Y2I7	1-phosphatidylinositol 3-phosphate 5-kinase	CBL_MET	1154:1156	DYR	CBL	0.9899	More...
Q9Y4F3	Meiosis regulator and mRNA stability factor 1	CBL_MET	799:801	DYR	CBL	0.8743	More...
Q9Y4X5	E3 ubiquitin-protein ligase ARIH1	CBL_MET	98:100	DYR	CBL	0.6904	More...
Q9Y6N7	Roundabout homolog 1	CBL_MET	1125:1127	DYR	CBL	0.919	More...
Q9Y6W3	Calpain-7	CBL_MET	764:766	DYR	CBL	0.8602	More...
O60330	Protocadherin gamma-A12	CBL_MET	890:892	DYR	CBL	0.5991	More...
P42696	RNA-binding protein 34	CBL_MET	32:34	DYR	CBL	0.8024	More...
Q2MJR0	Sprouty-related, EVH1 domain-containing protein 3	CBL_MET	222:224	DYR	CBL	0.9902	More...
Q2T9L4	Inhibitory synaptic factor 1	CBL_MET	138:140	DYR	CBL	0.7706	More...
Q53G44	Interferon-induced protein 44-like	CBL_MET	187:189	DYR	CBL	0.5931	More...
Q5SRI9	Glycoprotein endo-alpha-1,2-mannosidase	CBL_MET	426:428	DYR	CBL	0.9969	More...
Q66K14	TBC1 domain family member 9B	CBL_MET	997:999	DYR	CBL	0.9546	More...
Q6V1P9	Protocadherin-23	CBL_MET	1364:1366	DYR	CBL	0.9843	More...
Q96A35	39S ribosomal protein L24, mitochondrial	CBL_MET	103:105	DYR	CBL	0.8186	More...
Q9BRU2	Transcription elongation factor A protein-like 7	CBL_MET	53:55	DYR	CBL	0.8569	More...
Q9C0D7	Probable ribonuclease ZC3H12C	CBL_MET	616:618	DYR	CBL	0.8826	More...
Q9HCL0	Protocadherin-18	CBL_MET	942:944	DYR	CBL	0.8495	More...
Q9NW75	G patch domain-containing protein 2	CBL_MET	102:104	DYR	CBL	0.9895	More...
Q9UN70	Protocadherin gamma-C3	CBL_MET	892:894	DYR	CBL	0.7341	More...
Q9Y2H8	Zinc finger protein 510	CBL_MET	119:121	DYR	CBL	0.7189	More...
Q9Y5F7	Protocadherin gamma-C4	CBL_MET	207:209	DYR	CBL	0.7942	More...
Q9Y5F7	Protocadherin gamma-C4	CBL_MET	896:898	DYR	CBL	0.9198	More...
Q9Y5F8	Protocadherin gamma-B7	CBL_MET	887:889	DYR	CBL	0.6353	More...
Q9Y5F9	Protocadherin gamma-B6	CBL_MET	888:890	DYR	CBL	0.6971	More...
Q9Y5G0	Protocadherin gamma-B5	CBL_MET	881:883	DYR	CBL	0.7195	More...
Q9Y5G1	Protocadherin gamma-B3	CBL_MET	887:889	DYR	CBL	0.9024	More...
Q9Y5G2	Protocadherin gamma-B2	CBL_MET	889:891	DYR	CBL	0.8238	More...
Q9Y5G3	Protocadherin gamma-B1	CBL_MET	885:887	DYR	CBL	0.8647	More...
Q9Y5G4	Protocadherin gamma-A9	CBL_MET	890:892	DYR	CBL	0.8201	More...
Q9Y5G5	Protocadherin gamma-A8	CBL_MET	890:892	DYR	CBL	0.8995	More...
Q9Y5G9	Protocadherin gamma-A4	CBL_MET	920:922	DYR	CBL	0.9131	More...
Q9Y5H0	Protocadherin gamma-A3	CBL_MET	890:892	DYR	CBL	0.7424	More...
Q9Y5H1	Protocadherin gamma-A2	CBL_MET	890:892	DYR	CBL	0.8649	More...
Q9Y5H2	Protocadherin gamma-A11	CBL_MET	893:895	DYR	CBL	0.9276	More...
Q9Y5H4	Protocadherin gamma-A1	CBL_MET	889:891	DYR	CBL	0.69	More...
A2AJT9	BCLAF1 and THRAP3 family member 3	CBL_MET	280:282	DYR	CBL	0.8797	More...
A6NCL1	Geminin coiled-coil domain-containing protein 1	CBL_MET	244:246	DYR	CBL	0.9961	More...
O75526	RNA-binding motif protein, X-linked-like-2	CBL_MET	224:226	DYR	CBL	0.9863	More...
Q2TAA8	Translin-associated factor X-interacting protein 1	CBL_MET	27:29	DYR	CBL	0.7834	More...
Q5THK1	Protein PRR14L	CBL_MET	604:606	DYR	CBL	0.9146	More...
Q5VZ52	MORN repeat-containing protein 5	CBL_MET	137:139	DYR	CBL	0.9741	More...
Q8N944	APC membrane recruitment protein 3	CBL_MET	128:130	DYR	CBL	0.9544	More...
Q8WX39	Epididymal-specific lipocalin-9	CBL_MET	115:117	DYR	CBL	0.862	More...
Q96M34	Testis-specific expressed protein 55	CBL_MET	387:389	DYR	CBL	0.8215	More...
Q96M89	Coiled-coil domain-containing protein 138	CBL_MET	113:115	DYR	CBL	0.9465	More...
Q96RT6	cTAGE family member 2	CBL_MET	571:573	DYR	CBL	0.8733	More...
Q9BRR8	G patch domain-containing protein 1	CBL_MET	370:372	DYR	CBL	0.9884	More...
Q9H6Y2	WD repeat-containing protein 55	CBL_MET	334:336	DYR	CBL	0.7633	More...
Q9Y5G7	Protocadherin gamma-A6	CBL_MET	890:892	DYR	CBL	0.8811	More...
A1A4G5	Leukemia NUP98 fusion partner 1	CBL_MET	84:86	DYR	CBL	0.8519	More...
A6NKL6	Transmembrane protein 200C	CBL_MET	477:479	DYR	CBL	0.9502	More...
P0C7V6	Putative transcription factor SPT20 homolog-like 2	CBL_MET	148:150	DYR	CBL	0.5386	More...
Q3ZLR7	Transcription factor SPT20 homolog-like 1	CBL_MET	148:150	DYR	CBL	0.5131	More...
Q8N7X1	RNA-binding motif protein, X-linked-like-3	CBL_MET	271:273	DYR	CBL	0.9985	More...
F2Z3F1	Uncharacterized protein C5orf67	CBL_MET	42:44	DYR	CBL	0.5833	More...
Q8IXP5	Uncharacterized protein C11orf53	CBL_MET	67:69	DYR	CBL	0.9873	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons

Degron: DYR

Degron related mutations and impact score

Drug responses associated with KDR mutations

All proteins holding degron of DYR